High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 308 | 884 | | 5050 | 10182 | 749.7 | 126.97 | 42.65 | 71.54 | 594 | 652 | 686 | 713 | 737 | 762 | 805 | 871 | 942 | 0.0693 | 706 | 1.198 | 99.81 | 37.54 | 1 | 0.0493 | 249 | 0.0009 | 44.07 | 7.331 | 0.2040 | 578151.0 | 458000000 | 371000000000 | 308000000000000 | 0.4226 | 0.2196 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0068 | 0.0006 | 0.0285 | 0.0120 | 0.0415 | 0.0212 | 0.0388 | 0.0132 | 0.0616 | 0.0186 | 0.8190 | 0.9345 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0020 | 0.0006 | 0.0159 | 0.0120 | 0.0237 | 0.0212 | 0.0190 | 0.0116 | 0.0326 | 0.0178 | 0.9061 | 0.9369 | 0.0036 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0000 | 0.0169 | 1.0000 | 0.0495 | 0.0000 | 0.0579 | 0.0000 | 0.0760 | 0.0000 | 0.0893 | 0.0000 | 0.7045 | 0.0000 | 0.0027 | 0.0054 | 0.0125 | 0.0152 | 0.0411 | 0.0438 | 0.0585 | 0.0688 | 0.7520 | 6 | 8 | 9 | 11 | 13 | 19 | 36 | 60 | 109 | 0.1640 | 2.95 | 2.935 | 0.7102 | 6935.9 | 2170000 | 941000000 | 501000000000 | 0.4404 | 0.1899 | 0.0194 | 0.0075 | 0.0535 | 0.0125 | 0.1069 | 0.0337 | 0.1470 | 0.0580 | 0.1701 | 0.1079 | 0.1750 | 0.1341 | 0.1665 | 0.1248 | 0.1130 | 0.1622 | 0.0486 | 0.3593 | 0.0013 | 0.0014 | 0.0041 | 0.0022 | 0.0048 | 0.0064 | 0.0153 | 0.0160 | 0.0396 | 0.0329 | 0.0616 | 0.0440 | 0.0517 | 0.0442 | 0.0727 | 0.0650 | 0.7490 | 0.7879 | 0.0017 | 0.0020 | 0.0043 | 0.0035 | 0.0108 | 0.0055 | 0.0208 | 0.0179 | 0.0554 | 0.0546 | 0.0705 | 0.0789 | 0.0575 | 0.0645 | 0.0809 | 0.0904 | 0.6981 | 0.6827 | 0.0015 | 0.0037 | 0.0104 | 0.0186 | 0.0443 | 0.0707 | 0.0592 | 0.0878 | 0.7039 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 305 | | 577 | 1224 | 107.4 | 19.71 | 5.63 | 1.94 | 82 | 89 | 96 | 101 | 108 | 113 | 118 | 125 | 133 | 0.2230 | 273 | 1.197 | 35.36 | 14.21 | 1 | 0.1664 | 96 | 0.0277 | 1.58 | 3.824 | 0.5880 | 11913.2 | 1360000 | 161000000 | 19400000000 | 0.3940 | 0.2372 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0051 | 0.0000 | 0.0304 | 0.0018 | 0.0658 | 0.0406 | 0.1392 | 0.0689 | 0.1342 | 0.0548 | 0.1519 | 0.0707 | 0.4709 | 0.7633 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0000 | 0.0000 | 0.0143 | 0.0017 | 0.0369 | 0.0399 | 0.0656 | 0.0624 | 0.0615 | 0.0295 | 0.0820 | 0.0503 | 0.7377 | 0.8163 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0968 | 0.6364 | 0.1290 | 0.1818 | 0.2796 | 0.0909 | 0.1075 | 0.0909 | 0.1398 | 0.0000 | 0.2473 | 0.0000 | 0.0034 | 0.0068 | 0.0169 | 0.0203 | 0.0811 | 0.0980 | 0.0743 | 0.0845 | 0.6149 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0263 | 7.62 | 3.939 | 0.3680 | 35.5 | 244.168 | 1810.28 | 14316.1 | 0.5714 | 0.1153 | 0.0047 | 0.0000 | 0.0712 | 0.0040 | 0.1377 | 0.0160 | 0.2389 | 0.0419 | 0.2358 | 0.1028 | 0.2294 | 0.1766 | 0.0585 | 0.2535 | 0.0190 | 0.2685 | 0.0047 | 0.1367 | 0.0000 | 0.0000 | 0.0154 | 0.0019 | 0.0475 | 0.0065 | 0.1342 | 0.0260 | 0.1853 | 0.0854 | 0.2601 | 0.1365 | 0.1936 | 0.2201 | 0.1211 | 0.2934 | 0.0428 | 0.2303 | 0.3190 | 0.5467 | 0.3667 | 0.3333 | 0.1571 | 0.1067 | 0.1238 | 0.0133 | 0.0286 | 0.0000 | 0.0048 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0280 | 0.1226 | 0.1559 | 0.1961 | 0.2259 | 0.1471 | 0.0753 | 0.0350 | 0.0140 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 576 | 951 | | 438 | 2028 | 54.0 | 7.53 | 156.62 | 225.49 | 45 | 48 | 49 | 51 | 54 | 55 | 57 | 60 | 63 | 0.1686 | 342 | 0.895 | 78.01 | 22.20 | 1 | 0.4566 | 200 | 0.0096 | 10.55 | 4.855 | 0.3142 | 2971.3 | 166797 | 9560000 | 559000000 | 0.3875 | 0.2379 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0023 | 0.0262 | 0.0092 | 0.0945 | 0.0624 | 0.1260 | 0.0901 | 0.1811 | 0.0693 | 0.2520 | 0.1085 | 0.3123 | 0.6582 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0023 | 0.0193 | 0.0091 | 0.0578 | 0.0594 | 0.0988 | 0.0868 | 0.1012 | 0.0548 | 0.1518 | 0.0868 | 0.5639 | 0.7009 | 0.1765 | 0.0000 | 0.1765 | 0.2000 | 0.0588 | 0.2000 | 0.1765 | 0.6000 | 0.1176 | 0.0000 | 0.0294 | 0.0000 | 0.1765 | 0.0000 | 0.0882 | 0.0000 | 0.0000 | 0.0000 | 0.0136 | 0.0318 | 0.0227 | 0.0773 | 0.1364 | 0.1364 | 0.1500 | 0.2091 | 0.2227 | 17 | 21 | 28 | 41 | 64 | 99 | 142 | 241 | 425 | 0.0260 | 58.20 | 5.100 | 0.4350 | 75349.7 | 58100000 | 55000000000 | 57800000000000 | 0.4831 | 0.1439 | 0.1056 | 0.0000 | 0.2609 | 0.0221 | 0.2050 | 0.1838 | 0.0870 | 0.1569 | 0.1242 | 0.1936 | 0.0870 | 0.1201 | 0.0683 | 0.0760 | 0.0435 | 0.1176 | 0.0186 | 0.1299 | 0.0030 | 0.0000 | 0.0030 | 0.0036 | 0.0151 | 0.0059 | 0.0256 | 0.0119 | 0.0935 | 0.0973 | 0.1704 | 0.1269 | 0.0905 | 0.0973 | 0.1297 | 0.1329 | 0.4691 | 0.5243 | 0.0020 | 0.0000 | 0.0060 | 0.0069 | 0.0159 | 0.0207 | 0.0239 | 0.0345 | 0.1076 | 0.1310 | 0.1853 | 0.1816 | 0.1036 | 0.0989 | 0.1474 | 0.1402 | 0.4084 | 0.3862 | 0.0000 | 0.0035 | 0.0159 | 0.0265 | 0.1044 | 0.1805 | 0.0973 | 0.1274 | 0.4442 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 273 | 873 | | 959 | 20054 | 113.6 | 15.41 | 28.35 | 38.32 | 95 | 99 | 103 | 107 | 113 | 117 | 121 | 127 | 135 | 0.0524 | 1050 | 1.034 | 39.40 | 13.04 | 0 | 0.1064 | 102 | 0.0763 | 0.50 | 2.832 | 0.7708 | 13136.1 | 1550000 | 186000000 | 22800000000 | 0.4056 | 0.2400 | 0.0012 | 0.0000 | 0.0036 | 0.0010 | 0.0083 | 0.0031 | 0.0154 | 0.0073 | 0.0473 | 0.0241 | 0.0746 | 0.0640 | 0.0734 | 0.0325 | 0.1006 | 0.0598 | 0.6757 | 0.8080 | 0.0011 | 0.0000 | 0.0032 | 0.0010 | 0.0076 | 0.0031 | 0.0108 | 0.0073 | 0.0314 | 0.0229 | 0.0541 | 0.0615 | 0.0400 | 0.0250 | 0.0639 | 0.0532 | 0.7879 | 0.8259 | 0.0000 | 0.0000 | 0.0127 | 0.1667 | 0.0506 | 0.0000 | 0.1013 | 0.5000 | 0.1266 | 0.3333 | 0.1392 | 0.0000 | 0.1266 | 0.0000 | 0.1266 | 0.0000 | 0.3165 | 0.0000 | 0.0022 | 0.0043 | 0.0152 | 0.0260 | 0.0390 | 0.0758 | 0.0736 | 0.1017 | 0.6623 | 11 | 13 | 15 | 17 | 20 | 22 | 26 | 31 | 40 | 0.3245 | 0.91 | 1.880 | 0.8551 | 2272.4 | 507754 | 174000000 | 71000000000 | 0.5696 | 0.1296 | 0.0433 | 0.0176 | 0.0600 | 0.0218 | 0.0785 | 0.0264 | 0.1039 | 0.0386 | 0.1265 | 0.0642 | 0.1678 | 0.0809 | 0.1887 | 0.1079 | 0.1421 | 0.1846 | 0.0893 | 0.4581 | 0.0240 | 0.0144 | 0.0282 | 0.0178 | 0.0330 | 0.0204 | 0.0353 | 0.0280 | 0.0502 | 0.0467 | 0.0618 | 0.0603 | 0.0746 | 0.0721 | 0.1061 | 0.1150 | 0.5867 | 0.6253 | 0.0284 | 0.0348 | 0.0315 | 0.0221 | 0.0495 | 0.0172 | 0.0486 | 0.0255 | 0.0769 | 0.0594 | 0.0874 | 0.0790 | 0.0867 | 0.0795 | 0.1126 | 0.1286 | 0.4784 | 0.5540 | 0.0222 | 0.0261 | 0.0286 | 0.0380 | 0.0551 | 0.0752 | 0.0968 | 0.1505 | 0.5076 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 779 | 772 | | 630 | 2293 | 62.2 | 11.79 | 6.82 | 2.35 | 48 | 51 | 54 | 57 | 61 | 65 | 69 | 73 | 77 | 0.1522 | 349 | 0.662 | 34.06 | 7.21 | 2 | 0.1444 | 91 | 0.0668 | 0.76 | 2.979 | 0.7113 | 4008.3 | 267309 | 18400000 | 1310000000 | 0.4337 | 0.1967 | 0.0000 | 0.0000 | 0.0115 | 0.0000 | 0.0253 | 0.0016 | 0.0484 | 0.0081 | 0.1106 | 0.0520 | 0.1521 | 0.0846 | 0.1728 | 0.0618 | 0.2166 | 0.1317 | 0.2627 | 0.6602 | 0.0000 | 0.0000 | 0.0038 | 0.0000 | 0.0075 | 0.0016 | 0.0226 | 0.0048 | 0.0658 | 0.0476 | 0.0921 | 0.0778 | 0.0714 | 0.0429 | 0.1372 | 0.0984 | 0.5996 | 0.7270 | 0.0102 | 0.1333 | 0.0408 | 0.0000 | 0.0612 | 0.1333 | 0.1633 | 0.4000 | 0.1837 | 0.0000 | 0.2245 | 0.2667 | 0.1224 | 0.0000 | 0.1020 | 0.0000 | 0.0918 | 0.0667 | 0.0000 | 0.0000 | 0.0065 | 0.0647 | 0.0971 | 0.1100 | 0.1197 | 0.1553 | 0.4466 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 10 | 0.0239 | 6.69 | 4.216 | 0.3943 | 52.0 | 441.077 | 4128.92 | 42300.9 | 0.5603 | 0.1272 | 0.0098 | 0.0035 | 0.0446 | 0.0081 | 0.1223 | 0.0190 | 0.1982 | 0.0432 | 0.2580 | 0.0876 | 0.1839 | 0.1643 | 0.1205 | 0.2190 | 0.0509 | 0.2824 | 0.0116 | 0.1729 | 0.0044 | 0.0000 | 0.0196 | 0.0010 | 0.0418 | 0.0068 | 0.0982 | 0.0209 | 0.1483 | 0.0507 | 0.1781 | 0.0989 | 0.1749 | 0.1495 | 0.1477 | 0.2567 | 0.1869 | 0.4155 | 0.1638 | 0.1855 | 0.1048 | 0.0943 | 0.1114 | 0.1006 | 0.1048 | 0.1132 | 0.1201 | 0.1226 | 0.1004 | 0.1164 | 0.1048 | 0.1069 | 0.0873 | 0.0943 | 0.1026 | 0.0660 | 0.0254 | 0.0806 | 0.1569 | 0.1490 | 0.1350 | 0.1060 | 0.1060 | 0.0947 | 0.1464 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1140 | 800 | | 415 | 10014 | 37.5 | 8.37 | 298.79 | 356.44 | 26 | 30 | 32 | 35 | 37 | 40 | 42 | 45 | 48 | 0.0520 | 521 | 0.700 | 202.20 | 35.61 | 2 | 1.1663 | 484 | 0.0170 | 4.33 | 4.301 | 0.4484 | 1479.7 | 60857.1 | 2600000 | 115000000 | 0.3546 | 0.2708 | 0.0000 | 0.0000 | 0.0083 | 0.0000 | 0.0373 | 0.0025 | 0.1037 | 0.0176 | 0.2241 | 0.0529 | 0.2033 | 0.0856 | 0.1867 | 0.1058 | 0.1743 | 0.1738 | 0.0622 | 0.5617 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0127 | 0.0025 | 0.0538 | 0.0173 | 0.0854 | 0.0519 | 0.0918 | 0.0765 | 0.1076 | 0.0914 | 0.1424 | 0.1136 | 0.5032 | 0.6469 | 0.0533 | 0.2500 | 0.0800 | 0.0000 | 0.0533 | 0.0000 | 0.2000 | 0.3750 | 0.1600 | 0.2500 | 0.1467 | 0.1250 | 0.2133 | 0.0000 | 0.0533 | 0.0000 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0291 | 0.0825 | 0.1311 | 0.1602 | 0.1408 | 0.1748 | 0.2816 | 16 | 19 | 26 | 56 | 134 | 250 | 397 | 574 | 843 | 0.0362 | 50.93 | 5.899 | 0.4283 | 216312.0 | 203000000 | 220000000000 | 261000000000000 | 0.5151 | 0.1616 | 0.0713 | 0.0006 | 0.1940 | 0.0107 | 0.2691 | 0.1146 | 0.2078 | 0.1740 | 0.1352 | 0.1960 | 0.0701 | 0.1829 | 0.0250 | 0.1140 | 0.0163 | 0.1146 | 0.0113 | 0.0926 | 0.0002 | 0.0000 | 0.0002 | 0.0009 | 0.0022 | 0.0018 | 0.0115 | 0.0112 | 0.0583 | 0.0497 | 0.0937 | 0.0790 | 0.0718 | 0.0645 | 0.0976 | 0.0919 | 0.6644 | 0.7012 | 0.0003 | 0.0007 | 0.0018 | 0.0045 | 0.0055 | 0.0111 | 0.0210 | 0.0236 | 0.0735 | 0.0748 | 0.1104 | 0.1219 | 0.0921 | 0.0890 | 0.1052 | 0.1126 | 0.5902 | 0.5618 | 0.0003 | 0.0005 | 0.0027 | 0.0156 | 0.0648 | 0.1058 | 0.0826 | 0.1017 | 0.6260 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 209 | 861 | | 543 | 4357 | 152.9 | 32.22 | 90.49 | 146.81 | 112 | 125 | 134 | 144 | 152 | 161 | 170 | 181 | 194 | 0.0925 | 403 | 1.074 | 82.81 | 25.61 | 1 | 0.3665 | 199 | 0.0040 | 21.07 | 5.680 | 0.2454 | 24410.0 | 4050000 | 697000000 | 124000000000 | 0.4295 | 0.2088 | 0.0000 | 0.0000 | 0.0029 | 0.0000 | 0.0029 | 0.0000 | 0.0632 | 0.0078 | 0.1523 | 0.0447 | 0.1638 | 0.0953 | 0.1868 | 0.0700 | 0.1782 | 0.1498 | 0.2500 | 0.6323 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0000 | 0.0000 | 0.0156 | 0.0075 | 0.0690 | 0.0413 | 0.0980 | 0.0732 | 0.0802 | 0.0450 | 0.1114 | 0.0994 | 0.6236 | 0.7336 | 0.0198 | 0.0000 | 0.0099 | 0.0000 | 0.0891 | 0.1053 | 0.1089 | 0.3684 | 0.1782 | 0.3684 | 0.1188 | 0.0526 | 0.1584 | 0.1053 | 0.1386 | 0.0000 | 0.1782 | 0.0000 | 0.0000 | 0.0075 | 0.0491 | 0.0340 | 0.1132 | 0.1208 | 0.1094 | 0.1245 | 0.4415 | 6 | 7 | 9 | 10 | 12 | 26 | 64 | 155 | 335 | 0.1505 | 5.85 | 3.608 | 0.6197 | 29737.3 | 12900000 | 6260000000 | 3270000000000 | 0.5075 | 0.1310 | 0.0714 | 0.0045 | 0.1939 | 0.0201 | 0.2041 | 0.0447 | 0.2857 | 0.1029 | 0.1276 | 0.2282 | 0.0867 | 0.2371 | 0.0255 | 0.1365 | 0.0051 | 0.1275 | 0.0000 | 0.0984 | 0.0016 | 0.0014 | 0.0008 | 0.0000 | 0.0016 | 0.0007 | 0.0195 | 0.0114 | 0.0568 | 0.0549 | 0.0860 | 0.0834 | 0.0543 | 0.0499 | 0.0933 | 0.0848 | 0.6861 | 0.7135 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0031 | 0.0145 | 0.0157 | 0.0685 | 0.0680 | 0.0858 | 0.0931 | 0.0559 | 0.0596 | 0.1022 | 0.1004 | 0.6702 | 0.6600 | 0.0009 | 0.0000 | 0.0027 | 0.0089 | 0.0608 | 0.0956 | 0.0536 | 0.0903 | 0.6872 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 56 | 911 | | 384 | 7332 | 60.6 | 12.76 | 165.06 | 118.18 | 45 | 50 | 53 | 57 | 60 | 63 | 67 | 71 | 76 | 0.0614 | 450 | 0.519 | 130.54 | 26.91 | 0 | 1.0260 | 394 | 0.0099 | 9.19 | 4.826 | 0.3167 | 3828.9 | 252540 | 17400000 | 1250000000 | 0.4554 | 0.1729 | 0.0036 | 0.0000 | 0.0109 | 0.0028 | 0.0182 | 0.0055 | 0.0691 | 0.0194 | 0.1309 | 0.0720 | 0.1709 | 0.1219 | 0.1782 | 0.0914 | 0.2000 | 0.1607 | 0.2182 | 0.5263 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0093 | 0.0027 | 0.0247 | 0.0107 | 0.0957 | 0.0587 | 0.1235 | 0.1147 | 0.1173 | 0.0667 | 0.1420 | 0.1333 | 0.4877 | 0.6107 | 0.1020 | 0.0000 | 0.0612 | 0.1429 | 0.1224 | 0.0714 | 0.1020 | 0.3571 | 0.1633 | 0.2857 | 0.1837 | 0.0714 | 0.1633 | 0.0714 | 0.0612 | 0.0000 | 0.0408 | 0.0000 | 0.0053 | 0.0000 | 0.0106 | 0.0638 | 0.1596 | 0.1702 | 0.1596 | 0.1915 | 0.2394 | 18 | 37 | 71 | 117 | 158 | 195 | 232 | 274 | 329 | 0.0075 | 22.50 | 6.081 | 0.3343 | 41207.1 | 12200000 | 3970000000 | 1400000000000 | 0.4642 | 0.1955 | 0.0148 | 0.0016 | 0.1134 | 0.0089 | 0.1997 | 0.0335 | 0.1935 | 0.0895 | 0.1671 | 0.1734 | 0.1507 | 0.1952 | 0.0870 | 0.1593 | 0.0583 | 0.1613 | 0.0155 | 0.1774 | 0.0000 | 0.0000 | 0.0005 | 0.0013 | 0.0024 | 0.0011 | 0.0128 | 0.0077 | 0.0443 | 0.0302 | 0.0775 | 0.0562 | 0.0828 | 0.0523 | 0.1239 | 0.0826 | 0.6558 | 0.7687 | 0.0003 | 0.0023 | 0.0052 | 0.0099 | 0.0108 | 0.0185 | 0.0241 | 0.0468 | 0.0927 | 0.1342 | 0.1524 | 0.1640 | 0.1405 | 0.1486 | 0.1552 | 0.1721 | 0.4188 | 0.3036 | 0.0011 | 0.0025 | 0.0040 | 0.0178 | 0.0627 | 0.1136 | 0.1110 | 0.1627 | 0.5246 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1215 | 861 | | 3007 | 9908 | 716.7 | 136.15 | 119.32 | 267.01 | 537 | 590 | 633 | 674 | 713 | 750 | 795 | 845 | 901 | 0.0779 | 772 | 1.131 | 79.76 | 31.58 | 2 | 0.0725 | 218 | 0.0010 | 52.74 | 7.117 | 0.1610 | 532255.0 | 408000000 | 323000000000 | 262000000000000 | 0.4330 | 0.2090 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0007 | 0.0651 | 0.0200 | 0.1481 | 0.0312 | 0.1456 | 0.0346 | 0.1792 | 0.0481 | 0.4484 | 0.8654 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0007 | 0.0316 | 0.0198 | 0.0643 | 0.0271 | 0.0583 | 0.0218 | 0.0671 | 0.0305 | 0.7723 | 0.9001 | 0.0040 | 0.0588 | 0.0059 | 0.0588 | 0.0198 | 0.0882 | 0.0931 | 0.3529 | 0.1802 | 0.2941 | 0.1842 | 0.0588 | 0.0911 | 0.0294 | 0.1564 | 0.0588 | 0.2653 | 0.0000 | 0.0000 | 0.0007 | 0.0041 | 0.0244 | 0.0807 | 0.1404 | 0.1065 | 0.1303 | 0.5129 | 7 | 9 | 10 | 11 | 13 | 16 | 31 | 132 | 393 | 0.2663 | 40.82 | 3.458 | 0.6732 | 85524.5 | 93100000 | 121000000000 | 174000000000000 | 0.6043 | 0.0864 | 0.1806 | 0.0164 | 0.2843 | 0.1228 | 0.2274 | 0.2439 | 0.1237 | 0.1735 | 0.1304 | 0.1571 | 0.0201 | 0.1489 | 0.0201 | 0.0687 | 0.0134 | 0.0491 | 0.0000 | 0.0196 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0059 | 0.0680 | 0.0675 | 0.1151 | 0.0990 | 0.0657 | 0.0671 | 0.1024 | 0.0998 | 0.6425 | 0.6607 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0115 | 0.0085 | 0.0781 | 0.0846 | 0.1289 | 0.1455 | 0.0849 | 0.0795 | 0.1226 | 0.1286 | 0.5734 | 0.5516 | 0.0000 | 0.0000 | 0.0010 | 0.0097 | 0.0711 | 0.1178 | 0.0808 | 0.1168 | 0.6027 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 84 | 350 | | 635 | 11961 | 63.2 | 10.04 | 161.70 | 197.63 | 50 | 54 | 57 | 61 | 63 | 66 | 68 | 71 | 76 | 0.0579 | 693 | 0.875 | 142.76 | 45.97 | 2 | 0.6299 | 400 | 0.0068 | 11.22 | 5.192 | 0.3174 | 4092.7 | 271580 | 18400000 | 1280000000 | 0.4246 | 0.2192 | 0.0020 | 0.0000 | 0.0061 | 0.0016 | 0.0242 | 0.0048 | 0.0364 | 0.0111 | 0.0667 | 0.0430 | 0.1091 | 0.0685 | 0.1172 | 0.0525 | 0.1960 | 0.0812 | 0.4424 | 0.7373 | 0.0018 | 0.0000 | 0.0053 | 0.0016 | 0.0124 | 0.0047 | 0.0284 | 0.0110 | 0.0443 | 0.0379 | 0.0585 | 0.0694 | 0.0709 | 0.0394 | 0.0816 | 0.0599 | 0.6968 | 0.7760 | 0.0580 | 0.3333 | 0.0870 | 0.0000 | 0.1594 | 0.3333 | 0.0725 | 0.3333 | 0.1739 | 0.0000 | 0.0870 | 0.0000 | 0.0580 | 0.0000 | 0.1014 | 0.0000 | 0.2029 | 0.0000 | 0.0060 | 0.0030 | 0.0328 | 0.0448 | 0.0836 | 0.1045 | 0.1104 | 0.1761 | 0.4388 | 14 | 18 | 22 | 31 | 58 | 116 | 205 | 315 | 458 | 0.0352 | 28.43 | 5.403 | 0.4619 | 65200.6 | 35400000 | 22500000000 | 16100000000000 | 0.5927 | 0.1032 | 0.1018 | 0.0034 | 0.2284 | 0.0353 | 0.3243 | 0.1826 | 0.1467 | 0.1894 | 0.1089 | 0.2031 | 0.0462 | 0.1570 | 0.0249 | 0.0990 | 0.0130 | 0.0728 | 0.0059 | 0.0575 | 0.0002 | 0.0000 | 0.0009 | 0.0004 | 0.0020 | 0.0022 | 0.0142 | 0.0124 | 0.0583 | 0.0519 | 0.0965 | 0.0944 | 0.0720 | 0.0609 | 0.0991 | 0.0924 | 0.6569 | 0.6855 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0029 | 0.0060 | 0.0195 | 0.0279 | 0.0776 | 0.0835 | 0.1193 | 0.1370 | 0.0921 | 0.0943 | 0.1271 | 0.1346 | 0.5598 | 0.5161 | 0.0002 | 0.0002 | 0.0027 | 0.0176 | 0.0677 | 0.1015 | 0.0832 | 0.1135 | 0.6134 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 727 | | 435 | 10158 | 216.6 | 37.95 | 134.54 | 228.49 | 169 | 184 | 193 | 205 | 215 | 223 | 235 | 249 | 268 | 0.0475 | 483 | 1.039 | 156.49 | 50.48 | 1 | 0.9218 | 401 | 0.0052 | 14.90 | 5.415 | 0.3014 | 48369.5 | 11100000 | 2630000000 | 636000000000 | 0.4349 | 0.2080 | 0.0000 | 0.0000 | 0.0096 | 0.0000 | 0.0096 | 0.0000 | 0.0382 | 0.0047 | 0.1019 | 0.0606 | 0.1656 | 0.0629 | 0.1624 | 0.0606 | 0.1943 | 0.0956 | 0.3185 | 0.7156 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0186 | 0.0023 | 0.0849 | 0.0621 | 0.1088 | 0.0552 | 0.0928 | 0.0437 | 0.1432 | 0.0759 | 0.5517 | 0.7609 | 0.0000 | 0.1667 | 0.0000 | 0.0000 | 0.0635 | 0.1667 | 0.1905 | 0.3333 | 0.1429 | 0.3333 | 0.2540 | 0.0000 | 0.1270 | 0.0000 | 0.0635 | 0.0000 | 0.1587 | 0.0000 | 0.0000 | 0.0095 | 0.0237 | 0.0616 | 0.1754 | 0.1469 | 0.1280 | 0.1801 | 0.2749 | 5 | 7 | 8 | 9 | 11 | 16 | 98 | 264 | 495 | 0.1308 | 20.25 | 3.815 | 0.5357 | 70302.5 | 49000000 | 40900000000 | 40000000000000 | 0.5326 | 0.1283 | 0.0600 | 0.0028 | 0.2086 | 0.0308 | 0.2229 | 0.1413 | 0.2086 | 0.1636 | 0.1400 | 0.2070 | 0.0686 | 0.1930 | 0.0514 | 0.1035 | 0.0371 | 0.0867 | 0.0029 | 0.0713 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0047 | 0.0269 | 0.0233 | 0.0561 | 0.0472 | 0.0326 | 0.0315 | 0.0668 | 0.0585 | 0.8136 | 0.8348 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0011 | 0.0020 | 0.0049 | 0.0053 | 0.0377 | 0.0422 | 0.0681 | 0.0763 | 0.0518 | 0.0666 | 0.0883 | 0.0849 | 0.7477 | 0.7223 | 0.0000 | 0.0000 | 0.0011 | 0.0029 | 0.0350 | 0.0622 | 0.0404 | 0.0733 | 0.7851 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 695 | 131 | | 413 | 5107 | 82.1 | 20.31 | 279.73 | 253.72 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 98 | 113 | 0.0832 | 425 | 0.434 | 131.03 | 25.55 | 1 | 1.0266 | 424 | 0.0060 | 18.02 | 5.295 | 0.2565 | 7150.1 | 660661 | 64600000 | 6650000000 | 0.4371 | 0.1916 | 0.0042 | 0.0027 | 0.0042 | 0.0000 | 0.0333 | 0.0027 | 0.0667 | 0.0239 | 0.2042 | 0.0557 | 0.1708 | 0.1326 | 0.1708 | 0.0849 | 0.1667 | 0.1618 | 0.1792 | 0.5358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0219 | 0.0121 | 0.0909 | 0.0388 | 0.1285 | 0.1068 | 0.1003 | 0.0485 | 0.1317 | 0.0801 | 0.5235 | 0.7136 | 0.0127 | 0.0000 | 0.0506 | 0.0571 | 0.0253 | 0.0286 | 0.1266 | 0.3143 | 0.2025 | 0.1429 | 0.1772 | 0.2571 | 0.1392 | 0.2000 | 0.1266 | 0.0000 | 0.1392 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0914 | 0.1452 | 0.1935 | 0.1774 | 0.1452 | 0.2366 | 25 | 49 | 96 | 153 | 212 | 275 | 354 | 477 | 655 | 0.0063 | 78.62 | 6.665 | 0.3190 | 142608.0 | 95700000 | 75600000000 | 66600000000000 | 0.5065 | 0.1700 | 0.0221 | 0.0019 | 0.0858 | 0.0044 | 0.1495 | 0.0386 | 0.1507 | 0.0880 | 0.1667 | 0.1381 | 0.1507 | 0.1837 | 0.1164 | 0.1343 | 0.0931 | 0.1279 | 0.0650 | 0.2831 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0010 | 0.0179 | 0.0102 | 0.0595 | 0.0459 | 0.0965 | 0.0856 | 0.0892 | 0.0652 | 0.1071 | 0.0883 | 0.6244 | 0.7037 | 0.0018 | 0.0007 | 0.0031 | 0.0044 | 0.0067 | 0.0095 | 0.0329 | 0.0352 | 0.0940 | 0.1232 | 0.1416 | 0.1576 | 0.1159 | 0.1188 | 0.1495 | 0.1503 | 0.4545 | 0.4003 | 0.0010 | 0.0015 | 0.0050 | 0.0223 | 0.0819 | 0.1166 | 0.1052 | 0.1454 | 0.5211 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1211 | 385 | | 718 | 1212 | 13.2 | 2.76 | 5.21 | 2.35 | 10 | 11 | 12 | 12 | 13 | 14 | 15 | 16 | 17 | 0.2682 | 325 | 1.148 | 21.38 | 7.81 | 0 | 0.0822 | 59 | 0.0132 | 6.44 | 4.544 | 0.3693 | 180.9 | 2583.19 | 38202.1 | 582955 | 0.4010 | 0.2283 | 0.0000 | 0.0000 | 0.0157 | 0.0000 | 0.0449 | 0.0029 | 0.0966 | 0.0057 | 0.1483 | 0.0474 | 0.2000 | 0.0417 | 0.2337 | 0.0560 | 0.1775 | 0.1365 | 0.0831 | 0.7098 | 0.0000 | 0.0000 | 0.0034 | 0.0000 | 0.0168 | 0.0014 | 0.0387 | 0.0056 | 0.0505 | 0.0435 | 0.0640 | 0.0379 | 0.0993 | 0.0323 | 0.1465 | 0.0660 | 0.5808 | 0.8132 | 0.0604 | 0.3125 | 0.0537 | 0.0625 | 0.1141 | 0.2500 | 0.1342 | 0.3125 | 0.2550 | 0.0625 | 0.2081 | 0.0000 | 0.0738 | 0.0000 | 0.0738 | 0.0000 | 0.0268 | 0.0000 | 0.0097 | 0.0243 | 0.0511 | 0.0560 | 0.0779 | 0.1046 | 0.1192 | 0.2628 | 0.2944 | 2 | 3 | 3 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0284 | 12.09 | 3.933 | 0.3051 | 32.7 | 230.466 | 1783.27 | 14976.5 | 0.4758 | 0.1575 | 0.1219 | 0.0058 | 0.3000 | 0.0437 | 0.3188 | 0.1152 | 0.1688 | 0.2274 | 0.0719 | 0.2332 | 0.0188 | 0.1997 | 0.0000 | 0.1268 | 0.0000 | 0.0423 | 0.0000 | 0.0058 | 0.0000 | 0.0000 | 0.0159 | 0.0000 | 0.0684 | 0.0056 | 0.1233 | 0.0519 | 0.2320 | 0.0935 | 0.2527 | 0.1213 | 0.2002 | 0.2241 | 0.0867 | 0.2676 | 0.0208 | 0.2361 | 0.0281 | 0.0685 | 0.1563 | 0.1980 | 0.2184 | 0.2843 | 0.2926 | 0.2513 | 0.2084 | 0.1396 | 0.0782 | 0.0457 | 0.0160 | 0.0102 | 0.0020 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0160 | 0.0688 | 0.1290 | 0.2359 | 0.2531 | 0.2015 | 0.0835 | 0.0123 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1152 | 223 | | 1691 | 12352 | 99.2 | 17.11 | 46.92 | 69.30 | 79 | 84 | 88 | 92 | 96 | 101 | 107 | 114 | 124 | 0.0508 | 627 | 1.190 | 91.98 | 34.23 | 1 | 0.1366 | 231 | 0.0065 | 7.72 | 5.324 | 0.3702 | 10134.8 | 1070000 | 116000000 | 12900000000 | 0.3875 | 0.2575 | 0.0008 | 0.0000 | 0.0040 | 0.0000 | 0.0127 | 0.0000 | 0.0343 | 0.0024 | 0.0741 | 0.0253 | 0.1076 | 0.0519 | 0.1139 | 0.0404 | 0.1777 | 0.0821 | 0.4749 | 0.7978 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0047 | 0.0000 | 0.0206 | 0.0018 | 0.0419 | 0.0231 | 0.0599 | 0.0420 | 0.0573 | 0.0213 | 0.0879 | 0.0390 | 0.7264 | 0.8729 | 0.0121 | 0.1176 | 0.0040 | 0.1765 | 0.0526 | 0.2353 | 0.0931 | 0.2941 | 0.1336 | 0.1176 | 0.1903 | 0.0588 | 0.1579 | 0.0000 | 0.1741 | 0.0000 | 0.1822 | 0.0000 | 0.0039 | 0.0065 | 0.0310 | 0.0233 | 0.0802 | 0.1125 | 0.1035 | 0.1475 | 0.4916 | 7 | 10 | 13 | 17 | 23 | 32 | 44 | 64 | 112 | 0.0318 | 9.40 | 4.580 | 0.5581 | 7003.8 | 2350000 | 1290000000 | 919000000000 | 0.6011 | 0.1309 | 0.0239 | 0.0061 | 0.0710 | 0.0163 | 0.1253 | 0.0476 | 0.1857 | 0.0850 | 0.1744 | 0.1282 | 0.1459 | 0.1473 | 0.1187 | 0.1486 | 0.1054 | 0.1514 | 0.0497 | 0.2694 | 0.0028 | 0.0028 | 0.0058 | 0.0052 | 0.0106 | 0.0099 | 0.0311 | 0.0268 | 0.0659 | 0.0579 | 0.0954 | 0.0806 | 0.0809 | 0.0798 | 0.1143 | 0.1059 | 0.5934 | 0.6311 | 0.0056 | 0.0063 | 0.0141 | 0.0117 | 0.0159 | 0.0184 | 0.0286 | 0.0284 | 0.0766 | 0.0755 | 0.1048 | 0.1172 | 0.0886 | 0.0893 | 0.1172 | 0.1247 | 0.5485 | 0.5286 | 0.0026 | 0.0105 | 0.0228 | 0.0324 | 0.0762 | 0.0964 | 0.0836 | 0.1155 | 0.5599 | ||
| SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1207 | 207 | | 6980 | 19624 | 335.7 | 74.32 | 299.24 | 411.18 | 218 | 282 | 315 | 337 | 355 | 370 | 382 | 395 | 412 | 0.0495 | 972 | 0.878 | 105.01 | 22.67 | 2 | 0.0338 | 236 | 0.0016 | 18.87 | 6.802 | 0.2595 | 118201.0 | 43000000 | 16000000000 | 6030000000000 | 0.3992 | 0.2312 | 0.0008 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0000 | 0.0151 | 0.0005 | 0.0362 | 0.0109 | 0.0496 | 0.0198 | 0.0603 | 0.0114 | 0.1042 | 0.0181 | 0.7262 | 0.9392 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0005 | 0.0117 | 0.0106 | 0.0200 | 0.0197 | 0.0164 | 0.0105 | 0.0219 | 0.0154 | 0.9264 | 0.9434 | 0.0234 | 0.1429 | 0.0263 | 0.0000 | 0.0536 | 0.4286 | 0.0623 | 0.2857 | 0.0837 | 0.1429 | 0.1003 | 0.0000 | 0.1120 | 0.0000 | 0.1324 | 0.0000 | 0.4060 | 0.0000 | 0.0007 | 0.0016 | 0.0028 | 0.0094 | 0.0211 | 0.0392 | 0.0446 | 0.0634 | 0.8170 | 12 | 16 | 20 | 28 | 78 | 180 | 350 | 599 | 943 | 0.0721 | 64.70 | 5.520 | 0.4930 | 258610.0 | 294000000 | 385000000000 | 559000000000000 | 0.4020 | 0.2305 | 0.0543 | 0.0023 | 0.2124 | 0.0098 | 0.3077 | 0.0976 | 0.1647 | 0.1574 | 0.1179 | 0.2237 | 0.0828 | 0.2003 | 0.0326 | 0.1140 | 0.0217 | 0.0910 | 0.0059 | 0.1039 | 0.0003 | 0.0000 | 0.0001 | 0.0001 | 0.0013 | 0.0004 | 0.0073 | 0.0059 | 0.0473 | 0.0415 | 0.0872 | 0.0708 | 0.0574 | 0.0514 | 0.0844 | 0.0737 | 0.7147 | 0.7561 | 0.0003 | 0.0002 | 0.0014 | 0.0008 | 0.0026 | 0.0025 | 0.0115 | 0.0140 | 0.0574 | 0.0661 | 0.1058 | 0.1190 | 0.0739 | 0.0814 | 0.1015 | 0.1092 | 0.6456 | 0.6068 | 0.0002 | 0.0005 | 0.0011 | 0.0070 | 0.0580 | 0.0920 | 0.0640 | 0.0926 | 0.6846 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 125 | 813 | | 4044 | 8852 | 602.6 | 91.52 | 41.19 | 63.75 | 467 | 546 | 581 | 603 | 621 | 637 | 653 | 670 | 697 | 0.0916 | 811 | 0.861 | 103.18 | 25.63 | 4 | 0.0601 | 243 | 0.0019 | 32.85 | 6.649 | 0.2422 | 371488.0 | 233000000 | 149000000000 | 95900000000000 | 0.4344 | 0.2018 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0008 | 0.0262 | 0.0168 | 0.0455 | 0.0300 | 0.0385 | 0.0173 | 0.0691 | 0.0297 | 0.8172 | 0.9055 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0008 | 0.0201 | 0.0167 | 0.0321 | 0.0289 | 0.0201 | 0.0157 | 0.0338 | 0.0282 | 0.8928 | 0.9097 | 0.0279 | 0.0000 | 0.0391 | 0.0000 | 0.0615 | 0.1429 | 0.1006 | 0.2857 | 0.1006 | 0.2857 | 0.1564 | 0.2857 | 0.1229 | 0.0000 | 0.0950 | 0.0000 | 0.2961 | 0.0000 | 0.0008 | 0.0021 | 0.0062 | 0.0181 | 0.0402 | 0.0743 | 0.0812 | 0.0952 | 0.6820 | 9 | 11 | 14 | 16 | 19 | 24 | 32 | 45 | 88 | 0.0559 | 3.74 | 3.856 | 0.6364 | 5760.6 | 1520000 | 505000000 | 191000000000 | 0.4879 | 0.1680 | 0.0222 | 0.0179 | 0.0677 | 0.0335 | 0.0812 | 0.0288 | 0.1141 | 0.0594 | 0.1460 | 0.0957 | 0.1470 | 0.0868 | 0.1692 | 0.1094 | 0.1335 | 0.1627 | 0.1190 | 0.4059 | 0.0058 | 0.0099 | 0.0173 | 0.0192 | 0.0142 | 0.0128 | 0.0242 | 0.0271 | 0.0468 | 0.0434 | 0.0560 | 0.0449 | 0.0629 | 0.0545 | 0.0844 | 0.0813 | 0.6884 | 0.7067 | 0.0032 | 0.0069 | 0.0153 | 0.0122 | 0.0159 | 0.0130 | 0.0312 | 0.0298 | 0.0503 | 0.0519 | 0.0751 | 0.0833 | 0.0649 | 0.0596 | 0.0808 | 0.0795 | 0.6635 | 0.6639 | 0.0049 | 0.0113 | 0.0157 | 0.0300 | 0.0458 | 0.0679 | 0.0684 | 0.0915 | 0.6644 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 644 | 509 | | 752 | 2601 | 109.3 | 22.70 | 27.66 | 36.83 | 79 | 89 | 97 | 104 | 110 | 117 | 123 | 130 | 139 | 0.1303 | 339 | 0.980 | 171.76 | 54.15 | 1 | 0.6197 | 466 | 0.0023 | 47.96 | 6.181 | 0.1607 | 12466.6 | 1470000 | 179000000 | 22400000000 | 0.3827 | 0.2423 | 0.0000 | 0.0000 | 0.0043 | 0.0000 | 0.0151 | 0.0000 | 0.0538 | 0.0042 | 0.1075 | 0.0379 | 0.1613 | 0.0618 | 0.1527 | 0.0520 | 0.2022 | 0.0758 | 0.3032 | 0.7683 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0114 | 0.0041 | 0.0507 | 0.0346 | 0.0654 | 0.0553 | 0.0670 | 0.0346 | 0.1029 | 0.0581 | 0.7010 | 0.8133 | 0.0204 | 0.0000 | 0.0272 | 0.0909 | 0.0612 | 0.3636 | 0.0952 | 0.2727 | 0.1837 | 0.0909 | 0.1361 | 0.1818 | 0.1633 | 0.0000 | 0.1769 | 0.0000 | 0.1361 | 0.0000 | 0.0000 | 0.0025 | 0.0101 | 0.0404 | 0.0783 | 0.1364 | 0.1364 | 0.1338 | 0.4621 | 13 | 14 | 15 | 16 | 17 | 18 | 21 | 29 | 50 | 0.5312 | 1.01 | 1.471 | 0.9002 | 2121.0 | 439440 | 138000000 | 49900000000 | 0.6286 | 0.0988 | 0.0545 | 0.0328 | 0.0955 | 0.0864 | 0.2136 | 0.1351 | 0.2136 | 0.1033 | 0.1727 | 0.1360 | 0.1091 | 0.1360 | 0.0909 | 0.1241 | 0.0364 | 0.1311 | 0.0136 | 0.1152 | 0.0104 | 0.0219 | 0.0104 | 0.0629 | 0.0207 | 0.0950 | 0.0370 | 0.0673 | 0.1111 | 0.0994 | 0.1156 | 0.0892 | 0.1319 | 0.1001 | 0.1452 | 0.1235 | 0.4178 | 0.3406 | 0.0000 | 0.0000 | 0.0022 | 0.0249 | 0.0198 | 0.0305 | 0.0440 | 0.0693 | 0.1604 | 0.1662 | 0.1758 | 0.1801 | 0.1297 | 0.1468 | 0.1714 | 0.1634 | 0.2967 | 0.2188 | 0.0036 | 0.0073 | 0.0146 | 0.0419 | 0.1421 | 0.1512 | 0.1275 | 0.1658 | 0.3461 |
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 726 | 600 | | 3242 | 14311 | 499.5 | 83.43 | 217.74 | 192.04 | 394 | 426 | 450 | 470 | 493 | 518 | 547 | 576 | 612 | 0.0641 | 917 | 0.675 | 101.83 | 25.18 | 1 | 0.0999 | 324 | 0.0014 | 30.06 | 6.786 | 0.2232 | 256441.0 | 135000000 | 73000000000 | 40400000000000 | 0.4615 | 0.1909 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0029 | 0.0003 | 0.0094 | 0.0019 | 0.0476 | 0.0128 | 0.1034 | 0.0350 | 0.0932 | 0.0172 | 0.1211 | 0.0428 | 0.6215 | 0.8900 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0031 | 0.0015 | 0.0241 | 0.0115 | 0.0544 | 0.0319 | 0.0457 | 0.0124 | 0.0582 | 0.0254 | 0.8139 | 0.9170 | 0.0069 | 0.2000 | 0.0185 | 0.2000 | 0.0254 | 0.1333 | 0.0762 | 0.2667 | 0.1224 | 0.0667 | 0.2517 | 0.1333 | 0.1201 | 0.0000 | 0.1386 | 0.0000 | 0.2402 | 0.0000 | 0.0026 | 0.0013 | 0.0110 | 0.0272 | 0.0725 | 0.1146 | 0.0881 | 0.1075 | 0.5751 | 27 | 59 | 91 | 117 | 149 | 197 | 277 | 373 | 502 | 0.0056 | 39.72 | 6.385 | 0.3525 | 84287.2 | 43400000 | 26300000000 | 17700000000000 | 0.5008 | 0.1648 | 0.0367 | 0.0032 | 0.1371 | 0.0092 | 0.2234 | 0.0566 | 0.1856 | 0.1095 | 0.1607 | 0.1802 | 0.1201 | 0.1909 | 0.0615 | 0.1404 | 0.0434 | 0.1268 | 0.0316 | 0.1831 | 0.0010 | 0.0008 | 0.0021 | 0.0015 | 0.0046 | 0.0040 | 0.0193 | 0.0143 | 0.0618 | 0.0534 | 0.0900 | 0.0837 | 0.0683 | 0.0638 | 0.1015 | 0.0908 | 0.6515 | 0.6878 | 0.0004 | 0.0008 | 0.0007 | 0.0042 | 0.0048 | 0.0124 | 0.0253 | 0.0287 | 0.0830 | 0.0944 | 0.1247 | 0.1404 | 0.1000 | 0.1138 | 0.1419 | 0.1548 | 0.5192 | 0.4506 | 0.0006 | 0.0023 | 0.0015 | 0.0250 | 0.0581 | 0.1139 | 0.0806 | 0.1154 | 0.6027 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 656 | 535 | | 6091 | 20546 | 242.4 | 44.53 | 137.26 | 192.39 | 187 | 203 | 216 | 228 | 239 | 251 | 264 | 280 | 303 | 0.0476 | 979 | 1.098 | 86.73 | 30.00 | 1 | 0.0368 | 224 | 0.0009 | 51.40 | 7.200 | 0.1626 | 60738.6 | 15700000 | 4190000000 | 1150000000000 | 0.4279 | 0.2267 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0016 | 0.0000 | 0.0124 | 0.0005 | 0.0636 | 0.0142 | 0.1292 | 0.0326 | 0.1368 | 0.0323 | 0.1768 | 0.0541 | 0.4789 | 0.8663 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0008 | 0.0000 | 0.0040 | 0.0002 | 0.0280 | 0.0117 | 0.0548 | 0.0216 | 0.0579 | 0.0143 | 0.0777 | 0.0241 | 0.7764 | 0.9281 | 0.0078 | 0.0464 | 0.0056 | 0.0265 | 0.0468 | 0.1126 | 0.1158 | 0.2649 | 0.1815 | 0.2119 | 0.2305 | 0.1854 | 0.1236 | 0.0795 | 0.1336 | 0.0530 | 0.1548 | 0.0199 | 0.0003 | 0.0010 | 0.0075 | 0.0369 | 0.0799 | 0.1438 | 0.1237 | 0.1565 | 0.4503 | 10 | 11 | 13 | 16 | 25 | 62 | 149 | 281 | 445 | 0.1040 | 21.77 | 4.771 | 0.5558 | 55854.0 | 29600000 | 17800000000 | 11700000000000 | 0.5221 | 0.1170 | 0.0474 | 0.0028 | 0.1966 | 0.0109 | 0.3034 | 0.1095 | 0.1798 | 0.1664 | 0.1433 | 0.2227 | 0.0870 | 0.1986 | 0.0267 | 0.1227 | 0.0128 | 0.0858 | 0.0030 | 0.0806 | 0.0003 | 0.0003 | 0.0009 | 0.0003 | 0.0017 | 0.0020 | 0.0094 | 0.0084 | 0.0422 | 0.0385 | 0.0682 | 0.0630 | 0.0444 | 0.0432 | 0.0669 | 0.0635 | 0.7660 | 0.7808 | 0.0002 | 0.0002 | 0.0002 | 0.0009 | 0.0014 | 0.0024 | 0.0088 | 0.0122 | 0.0505 | 0.0500 | 0.0741 | 0.0794 | 0.0549 | 0.0568 | 0.0763 | 0.0835 | 0.7338 | 0.7146 | 0.0005 | 0.0006 | 0.0024 | 0.0080 | 0.0436 | 0.0706 | 0.0510 | 0.0733 | 0.7499 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1257 | 588 | | 6871 | 2051 | 137.3 | 25.65 | 90.04 | 55.86 | 104 | 115 | 123 | 130 | 137 | 144 | 150 | 159 | 170 | 0.3667 | 752 | 0.924 | 92.78 | 24.76 | 1 | 0.0342 | 235 | 0.0024 | 19.20 | 6.305 | 0.2542 | 19504.3 | 2860000 | 432000000 | 67100000000 | 0.4703 | 0.1831 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0058 | 0.0004 | 0.0210 | 0.0004 | 0.0599 | 0.0142 | 0.1283 | 0.0298 | 0.1440 | 0.0322 | 0.2039 | 0.0594 | 0.4358 | 0.8634 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0004 | 0.0066 | 0.0001 | 0.0250 | 0.0117 | 0.0591 | 0.0222 | 0.0521 | 0.0126 | 0.0901 | 0.0273 | 0.7638 | 0.9256 | 0.0138 | 0.0690 | 0.0324 | 0.0621 | 0.0482 | 0.1724 | 0.1455 | 0.2621 | 0.1888 | 0.1862 | 0.1642 | 0.1517 | 0.1445 | 0.0759 | 0.1259 | 0.0207 | 0.1367 | 0.0000 | 0.0006 | 0.0048 | 0.0097 | 0.0311 | 0.0829 | 0.1268 | 0.1317 | 0.1622 | 0.4503 | 25 | 40 | 54 | 69 | 83 | 97 | 113 | 133 | 160 | 0.0056 | 13.56 | 5.596 | 0.3618 | 11225.5 | 1750000 | 329000000 | 72100000000 | 0.5016 | 0.1610 | 0.0194 | 0.0010 | 0.1282 | 0.0104 | 0.2039 | 0.0604 | 0.1942 | 0.1093 | 0.1515 | 0.1894 | 0.1612 | 0.2362 | 0.0971 | 0.1592 | 0.0291 | 0.1228 | 0.0155 | 0.1113 | 0.0008 | 0.0007 | 0.0067 | 0.0028 | 0.0193 | 0.0104 | 0.0469 | 0.0291 | 0.1182 | 0.0992 | 0.1869 | 0.1881 | 0.1090 | 0.1013 | 0.1534 | 0.1367 | 0.3588 | 0.4316 | 0.0074 | 0.0125 | 0.0251 | 0.0250 | 0.0457 | 0.0813 | 0.0959 | 0.1479 | 0.1504 | 0.1583 | 0.2021 | 0.1813 | 0.1239 | 0.1458 | 0.1431 | 0.1333 | 0.2065 | 0.1146 | 0.0022 | 0.0108 | 0.0390 | 0.0683 | 0.1354 | 0.1788 | 0.1365 | 0.1560 | 0.2730 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1271 | 351 | | 4157 | 9898 | 475.9 | 89.44 | 163.26 | 251.77 | 360 | 394 | 423 | 449 | 475 | 498 | 524 | 554 | 594 | 0.0813 | 805 | 1.028 | 152.20 | 40.79 | 2 | 0.0871 | 362 | 0.0008 | 73.60 | 7.318 | 0.1483 | 234454.0 | 119000000 | 62600000000 | 33700000000000 | 0.4174 | 0.2233 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0017 | 0.0000 | 0.0196 | 0.0010 | 0.0716 | 0.0187 | 0.1191 | 0.0382 | 0.1160 | 0.0296 | 0.1725 | 0.0500 | 0.4981 | 0.8625 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0069 | 0.0007 | 0.0343 | 0.0162 | 0.0480 | 0.0300 | 0.0474 | 0.0157 | 0.0809 | 0.0288 | 0.7811 | 0.9086 | 0.0000 | 0.0390 | 0.0204 | 0.0260 | 0.0471 | 0.1429 | 0.0973 | 0.2597 | 0.1476 | 0.2338 | 0.2057 | 0.1558 | 0.1350 | 0.0779 | 0.1162 | 0.0519 | 0.2308 | 0.0130 | 0.0010 | 0.0010 | 0.0048 | 0.0299 | 0.0676 | 0.1356 | 0.1236 | 0.1472 | 0.4894 | 7 | 10 | 13 | 22 | 39 | 75 | 136 | 293 | 547 | 0.0676 | 32.18 | 4.895 | 0.5343 | 90034.8 | 69000000 | 62100000000 | 62700000000000 | 0.5861 | 0.0893 | 0.0409 | 0.0025 | 0.1595 | 0.0187 | 0.2704 | 0.0934 | 0.2179 | 0.1214 | 0.1595 | 0.1766 | 0.0914 | 0.2054 | 0.0311 | 0.1350 | 0.0214 | 0.1180 | 0.0078 | 0.1290 | 0.0003 | 0.0003 | 0.0013 | 0.0017 | 0.0043 | 0.0049 | 0.0140 | 0.0129 | 0.0478 | 0.0466 | 0.0870 | 0.0765 | 0.0558 | 0.0552 | 0.0797 | 0.0797 | 0.7096 | 0.7222 | 0.0004 | 0.0000 | 0.0016 | 0.0017 | 0.0028 | 0.0043 | 0.0172 | 0.0170 | 0.0537 | 0.0679 | 0.1034 | 0.0909 | 0.0577 | 0.0635 | 0.0885 | 0.0905 | 0.6747 | 0.6642 | 0.0000 | 0.0026 | 0.0026 | 0.0125 | 0.0521 | 0.0922 | 0.0558 | 0.0845 | 0.6978 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 718 | 209 | | 6919 | 20153 | 439.9 | 83.94 | 59.12 | 60.79 | 328 | 364 | 393 | 418 | 442 | 465 | 486 | 511 | 544 | 0.0555 | 1118 | 1.097 | 116.93 | 36.89 | 1 | 0.0405 | 280 | 0.0010 | 31.34 | 7.121 | 0.1942 | 200514.0 | 94500000 | 45900000000 | 23000000000000 | 0.3868 | 0.2525 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0000 | 0.0112 | 0.0015 | 0.0437 | 0.0118 | 0.0766 | 0.0244 | 0.0951 | 0.0209 | 0.1280 | 0.0268 | 0.6427 | 0.9146 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0013 | 0.0171 | 0.0100 | 0.0281 | 0.0194 | 0.0344 | 0.0128 | 0.0426 | 0.0172 | 0.8730 | 0.9393 | 0.0040 | 0.0086 | 0.0081 | 0.0000 | 0.0424 | 0.0259 | 0.0727 | 0.2586 | 0.1354 | 0.0862 | 0.1687 | 0.1810 | 0.1343 | 0.1293 | 0.1384 | 0.0431 | 0.2960 | 0.2672 | 0.0003 | 0.0014 | 0.0020 | 0.0108 | 0.0519 | 0.0935 | 0.0896 | 0.1278 | 0.6227 | 8 | 10 | 14 | 25 | 40 | 57 | 76 | 99 | 135 | 0.0457 | 4.18 | 4.483 | 0.5799 | 7190.4 | 1330000 | 338000000 | 109000000000 | 0.4299 | 0.1814 | 0.0071 | 0.0015 | 0.0560 | 0.0042 | 0.1504 | 0.0171 | 0.2041 | 0.0543 | 0.2237 | 0.1277 | 0.1653 | 0.2005 | 0.1077 | 0.1668 | 0.0611 | 0.1704 | 0.0247 | 0.2575 | 0.0002 | 0.0001 | 0.0009 | 0.0008 | 0.0023 | 0.0018 | 0.0122 | 0.0087 | 0.0364 | 0.0271 | 0.0609 | 0.0475 | 0.0552 | 0.0389 | 0.0755 | 0.0611 | 0.7565 | 0.8141 | 0.0011 | 0.0011 | 0.0026 | 0.0037 | 0.0041 | 0.0073 | 0.0192 | 0.0257 | 0.0575 | 0.0690 | 0.0847 | 0.1021 | 0.0802 | 0.0802 | 0.1038 | 0.1182 | 0.6468 | 0.5927 | 0.0005 | 0.0010 | 0.0038 | 0.0132 | 0.0444 | 0.0754 | 0.0604 | 0.0891 | 0.7123 | ||
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1163 | 914 | | 2848 | 4080 | 128.2 | 26.29 | 72.09 | 52.48 | 98 | 106 | 112 | 118 | 124 | 131 | 140 | 151 | 166 | 0.1199 | 489 | 1.053 | 105.55 | 34.18 | 1 | 0.0952 | 271 | 0.0016 | 34.35 | 6.710 | 0.2008 | 17134.3 | 2390000 | 346000000 | 52000000000 | 0.4596 | 0.1985 | 0.0005 | 0.0000 | 0.0026 | 0.0000 | 0.0083 | 0.0011 | 0.0365 | 0.0033 | 0.0813 | 0.0228 | 0.1370 | 0.0538 | 0.1370 | 0.0435 | 0.1917 | 0.0748 | 0.4052 | 0.8007 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0021 | 0.0004 | 0.0153 | 0.0004 | 0.0425 | 0.0148 | 0.0689 | 0.0445 | 0.0669 | 0.0169 | 0.1102 | 0.0342 | 0.6929 | 0.8889 | 0.0060 | 0.0252 | 0.0099 | 0.0672 | 0.0298 | 0.0756 | 0.0736 | 0.2521 | 0.1650 | 0.2017 | 0.2107 | 0.1513 | 0.1233 | 0.0924 | 0.1551 | 0.1008 | 0.2266 | 0.0336 | 0.0031 | 0.0039 | 0.0164 | 0.0374 | 0.0997 | 0.1394 | 0.1012 | 0.1355 | 0.4634 | 25 | 34 | 43 | 51 | 59 | 69 | 81 | 99 | 131 | 0.0231 | 3.25 | 4.328 | 0.5781 | 7950.5 | 1300000 | 290000000 | 79400000000 | 0.5593 | 0.1262 | 0.0086 | 0.0015 | 0.0574 | 0.0068 | 0.1463 | 0.0181 | 0.1663 | 0.0556 | 0.1740 | 0.1171 | 0.1463 | 0.1679 | 0.1205 | 0.1445 | 0.1052 | 0.1723 | 0.0755 | 0.3163 | 0.0019 | 0.0011 | 0.0057 | 0.0032 | 0.0127 | 0.0081 | 0.0340 | 0.0218 | 0.0816 | 0.0567 | 0.1108 | 0.0820 | 0.1066 | 0.0753 | 0.1472 | 0.1137 | 0.4995 | 0.6383 | 0.0028 | 0.0063 | 0.0084 | 0.0063 | 0.0307 | 0.0378 | 0.0568 | 0.0908 | 0.1331 | 0.1311 | 0.1695 | 0.1702 | 0.1089 | 0.1059 | 0.1406 | 0.1248 | 0.3492 | 0.3266 | 0.0071 | 0.0065 | 0.0162 | 0.0518 | 0.0945 | 0.1579 | 0.1204 | 0.1379 | 0.4078 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 387 | 777 | | 3566 | 6931 | 639.4 | 107.04 | 10.06 | 4.66 | 486 | 547 | 588 | 620 | 651 | 674 | 700 | 732 | 773 | 0.0884 | 613 | 1.124 | 98.72 | 31.38 | 1 | 0.0670 | 239 | 0.0010 | 36.61 | 7.121 | 0.1989 | 420338.0 | 283000000 | 195000000000 | 137000000000000 | 0.3984 | 0.2382 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0000 | 0.0083 | 0.0003 | 0.0320 | 0.0164 | 0.0531 | 0.0288 | 0.0531 | 0.0164 | 0.0753 | 0.0257 | 0.7708 | 0.9124 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0003 | 0.0186 | 0.0158 | 0.0258 | 0.0270 | 0.0225 | 0.0141 | 0.0287 | 0.0217 | 0.9000 | 0.9211 | 0.0000 | 0.0000 | 0.0149 | 0.1667 | 0.0446 | 0.0833 | 0.0718 | 0.2500 | 0.0767 | 0.2500 | 0.1287 | 0.2500 | 0.0965 | 0.0000 | 0.1658 | 0.0000 | 0.4010 | 0.0000 | 0.0010 | 0.0005 | 0.0021 | 0.0124 | 0.0361 | 0.0465 | 0.0589 | 0.0780 | 0.7646 | 5 | 7 | 7 | 8 | 9 | 10 | 12 | 13 | 16 | 0.4127 | 0.30 | 1.079 | 0.7896 | 122.9 | 1790.87 | 30353.2 | 582290 | 0.5361 | 0.1291 | 0.0335 | 0.0045 | 0.0959 | 0.0139 | 0.1633 | 0.0252 | 0.2000 | 0.0536 | 0.2138 | 0.0902 | 0.1661 | 0.1532 | 0.0951 | 0.2086 | 0.0264 | 0.2648 | 0.0059 | 0.1859 | 0.0097 | 0.0003 | 0.0311 | 0.0027 | 0.0593 | 0.0058 | 0.0757 | 0.0236 | 0.0929 | 0.0587 | 0.1048 | 0.1040 | 0.1018 | 0.1321 | 0.1193 | 0.1860 | 0.4054 | 0.4869 | 0.0652 | 0.0615 | 0.0666 | 0.0608 | 0.0576 | 0.0615 | 0.0566 | 0.0660 | 0.0756 | 0.0801 | 0.0809 | 0.1008 | 0.0856 | 0.1127 | 0.1365 | 0.1579 | 0.3754 | 0.2987 | 0.0501 | 0.0714 | 0.0772 | 0.0740 | 0.0778 | 0.0730 | 0.0804 | 0.1126 | 0.3836 |