High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 518 | 503 | | 15648 | 56021 | 320.9 | 59.50 | 142.33 | 181.99 | 244 | 279 | 299 | 315 | 329 | 341 | 354 | 368 | 389 | 0.0239 | 1341 | 0.987 | 126.85 | 36.01 | 1 | 0.0202 | 316 | 0.0015 | 21.65 | 6.855 | 0.2488 | 106538.0 | 36300000 | 12600000000 | 4480000000000 | 0.4413 | 0.2040 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0079 | 0.0003 | 0.0295 | 0.0078 | 0.0562 | 0.0157 | 0.0615 | 0.0104 | 0.0915 | 0.0162 | 0.7503 | 0.9496 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0023 | 0.0003 | 0.0109 | 0.0075 | 0.0242 | 0.0143 | 0.0210 | 0.0081 | 0.0316 | 0.0119 | 0.9098 | 0.9580 | 0.0090 | 0.0536 | 0.0157 | 0.0179 | 0.0336 | 0.1429 | 0.0745 | 0.2143 | 0.1272 | 0.1429 | 0.1557 | 0.1607 | 0.1429 | 0.1071 | 0.1597 | 0.0357 | 0.2818 | 0.1250 | 0.0008 | 0.0025 | 0.0050 | 0.0158 | 0.0410 | 0.0684 | 0.0815 | 0.0977 | 0.6873 | 8 | 10 | 12 | 18 | 51 | 108 | 178 | 269 | 424 | 0.1076 | 16.66 | 4.969 | 0.5393 | 53375.8 | 26600000 | 15300000000 | 9680000000000 | 0.3694 | 0.2725 | 0.0166 | 0.0013 | 0.1012 | 0.0060 | 0.2168 | 0.0361 | 0.1910 | 0.0912 | 0.1770 | 0.1724 | 0.1403 | 0.2115 | 0.0824 | 0.1547 | 0.0457 | 0.1475 | 0.0291 | 0.1792 | 0.0006 | 0.0002 | 0.0006 | 0.0006 | 0.0027 | 0.0015 | 0.0085 | 0.0065 | 0.0354 | 0.0299 | 0.0682 | 0.0565 | 0.0555 | 0.0459 | 0.0719 | 0.0641 | 0.7567 | 0.7947 | 0.0005 | 0.0005 | 0.0022 | 0.0022 | 0.0040 | 0.0048 | 0.0126 | 0.0154 | 0.0463 | 0.0551 | 0.0837 | 0.0934 | 0.0695 | 0.0743 | 0.0862 | 0.0911 | 0.6950 | 0.6633 | 0.0005 | 0.0017 | 0.0041 | 0.0114 | 0.0416 | 0.0737 | 0.0613 | 0.0797 | 0.7260 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 969 | 728 | | 16378 | 49009 | 195.5 | 37.68 | 203.96 | 331.62 | 151 | 169 | 180 | 189 | 198 | 206 | 215 | 226 | 241 | 0.0278 | 1362 | 1.188 | 93.09 | 34.48 | 1 | 0.0143 | 235 | 0.0032 | 12.80 | 6.161 | 0.3225 | 39638.5 | 8270000 | 1770000000 | 387000000000 | 0.4222 | 0.2262 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0000 | 0.0129 | 0.0003 | 0.0346 | 0.0080 | 0.0661 | 0.0181 | 0.0824 | 0.0160 | 0.1152 | 0.0268 | 0.6836 | 0.9309 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0036 | 0.0001 | 0.0120 | 0.0068 | 0.0260 | 0.0139 | 0.0283 | 0.0069 | 0.0418 | 0.0107 | 0.8870 | 0.9616 | 0.0089 | 0.0576 | 0.0166 | 0.0995 | 0.0426 | 0.1047 | 0.0736 | 0.1780 | 0.1192 | 0.1937 | 0.1473 | 0.1675 | 0.1256 | 0.0733 | 0.1456 | 0.0890 | 0.3206 | 0.0366 | 0.0012 | 0.0027 | 0.0072 | 0.0202 | 0.0501 | 0.0834 | 0.0821 | 0.1197 | 0.6333 | 7 | 8 | 10 | 12 | 17 | 54 | 192 | 390 | 701 | 0.1432 | 35.53 | 4.788 | 0.5519 | 151568.0 | 149000000 | 169000000000 | 211000000000000 | 0.4292 | 0.2197 | 0.0529 | 0.0035 | 0.2034 | 0.0131 | 0.2775 | 0.1127 | 0.1544 | 0.1604 | 0.1262 | 0.2014 | 0.0909 | 0.1979 | 0.0516 | 0.1081 | 0.0322 | 0.1003 | 0.0110 | 0.1027 | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.0010 | 0.0003 | 0.0081 | 0.0057 | 0.0395 | 0.0371 | 0.0691 | 0.0641 | 0.0487 | 0.0414 | 0.0700 | 0.0648 | 0.7633 | 0.7864 | 0.0004 | 0.0003 | 0.0011 | 0.0011 | 0.0028 | 0.0036 | 0.0129 | 0.0138 | 0.0452 | 0.0466 | 0.0753 | 0.0825 | 0.0565 | 0.0561 | 0.0729 | 0.0789 | 0.7329 | 0.7170 | 0.0001 | 0.0013 | 0.0022 | 0.0102 | 0.0423 | 0.0730 | 0.0512 | 0.0723 | 0.7473 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 234 | 799 | | 13982 | 47347 | 267.6 | 72.72 | 111.48 | 151.15 | 180 | 206 | 227 | 244 | 261 | 277 | 298 | 324 | 366 | 0.0290 | 1375 | 0.637 | 134.38 | 29.41 | 4 | 0.0255 | 356 | 0.0013 | 25.91 | 6.963 | 0.2170 | 76872.3 | 23600000 | 7750000000 | 2700000000000 | 0.4326 | 0.2214 | 0.0001 | 0.0000 | 0.0013 | 0.0001 | 0.0055 | 0.0004 | 0.0221 | 0.0029 | 0.0806 | 0.0231 | 0.1501 | 0.0550 | 0.1533 | 0.0526 | 0.1827 | 0.0775 | 0.4043 | 0.7885 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0002 | 0.0076 | 0.0010 | 0.0363 | 0.0137 | 0.0660 | 0.0277 | 0.0623 | 0.0230 | 0.0865 | 0.0394 | 0.7392 | 0.8952 | 0.0052 | 0.0034 | 0.0097 | 0.0101 | 0.0207 | 0.0151 | 0.0446 | 0.0772 | 0.1034 | 0.1394 | 0.1383 | 0.2065 | 0.0906 | 0.0999 | 0.1317 | 0.1360 | 0.4557 | 0.3123 | 0.0005 | 0.0028 | 0.0097 | 0.0328 | 0.0738 | 0.1215 | 0.0977 | 0.1158 | 0.5454 | 7 | 9 | 11 | 16 | 39 | 79 | 133 | 204 | 314 | 0.0819 | 10.81 | 4.504 | 0.5328 | 35272.3 | 16700000 | 10300000000 | 7940000000000 | 0.3283 | 0.3071 | 0.0637 | 0.0018 | 0.1924 | 0.0219 | 0.2593 | 0.1299 | 0.1590 | 0.1336 | 0.1409 | 0.1843 | 0.0919 | 0.1786 | 0.0492 | 0.1220 | 0.0306 | 0.1122 | 0.0130 | 0.1156 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0005 | 0.0071 | 0.0063 | 0.0513 | 0.0394 | 0.0875 | 0.0698 | 0.0707 | 0.0553 | 0.1096 | 0.0865 | 0.6726 | 0.7417 | 0.0003 | 0.0002 | 0.0010 | 0.0011 | 0.0030 | 0.0057 | 0.0155 | 0.0207 | 0.0717 | 0.0816 | 0.1258 | 0.1367 | 0.0873 | 0.0954 | 0.1313 | 0.1337 | 0.5642 | 0.5249 | 0.0001 | 0.0005 | 0.0021 | 0.0105 | 0.0627 | 0.1064 | 0.0809 | 0.1220 | 0.6149 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 903 | 431 | | 54613 | 82874 | 84.8 | 46.65 | 114.00 | 205.41 | 23 | 28 | 54 | 73 | 87 | 99 | 112 | 126 | 146 | 0.0303 | 2514 | 0.607 | 231.82 | 52.47 | 24 | 0.0118 | 645 | 0.0046 | 13.65 | 6.351 | 0.3627 | 9367.0 | 1190000 | 165000000 | 24700000000 | 0.5125 | 0.1476 | 0.0017 | 0.0007 | 0.0076 | 0.0010 | 0.0380 | 0.0040 | 0.0801 | 0.0150 | 0.1435 | 0.0575 | 0.1828 | 0.1084 | 0.1675 | 0.1062 | 0.1626 | 0.1362 | 0.2163 | 0.5709 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0002 | 0.0055 | 0.0015 | 0.0213 | 0.0119 | 0.0388 | 0.0234 | 0.0374 | 0.0198 | 0.0551 | 0.0316 | 0.8399 | 0.9117 | 0.0006 | 0.0018 | 0.0028 | 0.0048 | 0.0065 | 0.0130 | 0.0229 | 0.0391 | 0.0576 | 0.0808 | 0.0882 | 0.1189 | 0.0857 | 0.0985 | 0.1117 | 0.1228 | 0.6241 | 0.5203 | 0.0004 | 0.0014 | 0.0040 | 0.0124 | 0.0339 | 0.0605 | 0.0589 | 0.0824 | 0.7461 | 10 | 12 | 13 | 15 | 18 | 26 | 61 | 174 | 383 | 0.2390 | 19.16 | 3.787 | 0.6638 | 55186.4 | 40400000 | 36400000000 | 37700000000000 | 0.4605 | 0.1949 | 0.1576 | 0.0035 | 0.3814 | 0.0611 | 0.3071 | 0.3277 | 0.0839 | 0.2234 | 0.0408 | 0.1726 | 0.0158 | 0.1086 | 0.0071 | 0.0487 | 0.0039 | 0.0298 | 0.0026 | 0.0245 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0013 | 0.0008 | 0.0117 | 0.0106 | 0.0652 | 0.0602 | 0.1027 | 0.0939 | 0.0640 | 0.0575 | 0.0983 | 0.0881 | 0.6561 | 0.6885 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0020 | 0.0025 | 0.0164 | 0.0184 | 0.0742 | 0.0778 | 0.1173 | 0.1225 | 0.0764 | 0.0817 | 0.1085 | 0.1098 | 0.6044 | 0.5860 | 0.0001 | 0.0002 | 0.0017 | 0.0132 | 0.0722 | 0.1105 | 0.0693 | 0.1056 | 0.6272 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 803 | 843 | | 8078 | 37469 | 422.2 | 79.09 | 159.69 | 223.20 | 327 | 354 | 375 | 397 | 417 | 437 | 459 | 489 | 531 | 0.0317 | 1189 | 1.189 | 110.68 | 36.67 | 1 | 0.0326 | 263 | 0.0007 | 56.32 | 7.529 | 0.1530 | 184520.0 | 83400000 | 38900000000 | 18700000000000 | 0.4100 | 0.2411 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0026 | 0.0001 | 0.0130 | 0.0004 | 0.0471 | 0.0139 | 0.1043 | 0.0293 | 0.1147 | 0.0226 | 0.1480 | 0.0455 | 0.5695 | 0.8882 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0050 | 0.0000 | 0.0239 | 0.0107 | 0.0515 | 0.0209 | 0.0493 | 0.0112 | 0.0688 | 0.0227 | 0.8000 | 0.9344 | 0.0074 | 0.0206 | 0.0033 | 0.0155 | 0.0294 | 0.0722 | 0.0711 | 0.1598 | 0.1266 | 0.2268 | 0.1585 | 0.1701 | 0.1152 | 0.1495 | 0.1479 | 0.0979 | 0.3407 | 0.0876 | 0.0005 | 0.0054 | 0.0099 | 0.0311 | 0.0677 | 0.1022 | 0.1066 | 0.1196 | 0.5569 | 8 | 12 | 18 | 34 | 59 | 102 | 172 | 277 | 460 | 0.0551 | 26.43 | 5.339 | 0.4890 | 75319.8 | 53300000 | 47300000000 | 49000000000000 | 0.3610 | 0.2741 | 0.0647 | 0.0026 | 0.2087 | 0.0190 | 0.2734 | 0.1221 | 0.1568 | 0.1521 | 0.1237 | 0.2054 | 0.0877 | 0.1850 | 0.0465 | 0.1224 | 0.0270 | 0.0989 | 0.0115 | 0.0926 | 0.0006 | 0.0004 | 0.0007 | 0.0010 | 0.0031 | 0.0025 | 0.0146 | 0.0116 | 0.0594 | 0.0555 | 0.0986 | 0.0841 | 0.0693 | 0.0619 | 0.0969 | 0.0912 | 0.6568 | 0.6917 | 0.0009 | 0.0003 | 0.0015 | 0.0012 | 0.0039 | 0.0068 | 0.0169 | 0.0173 | 0.0767 | 0.0907 | 0.1116 | 0.1149 | 0.0824 | 0.0817 | 0.1129 | 0.1235 | 0.5932 | 0.5636 | 0.0006 | 0.0018 | 0.0039 | 0.0139 | 0.0709 | 0.1068 | 0.0718 | 0.1079 | 0.6224 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 842 | 577 | | 8312 | 37624 | 297.8 | 91.57 | 178.27 | 259.96 | 160 | 206 | 245 | 278 | 307 | 333 | 362 | 387 | 411 | 0.0319 | 1200 | 0.839 | 102.04 | 23.02 | 1 | 0.0298 | 248 | 0.0012 | 10.68 | 6.901 | 0.3043 | 97039.9 | 33700000 | 12200000000 | 4600000000000 | 0.3862 | 0.2351 | 0.0012 | 0.0000 | 0.0021 | 0.0005 | 0.0039 | 0.0017 | 0.0170 | 0.0054 | 0.0499 | 0.0240 | 0.0762 | 0.0398 | 0.0810 | 0.0408 | 0.1043 | 0.0580 | 0.6643 | 0.8299 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0003 | 0.0001 | 0.0033 | 0.0020 | 0.0152 | 0.0128 | 0.0244 | 0.0202 | 0.0207 | 0.0155 | 0.0268 | 0.0229 | 0.9088 | 0.9263 | 0.0015 | 0.0106 | 0.0030 | 0.0151 | 0.0049 | 0.0408 | 0.0118 | 0.0711 | 0.0323 | 0.0968 | 0.0433 | 0.1452 | 0.0429 | 0.0953 | 0.0771 | 0.1589 | 0.7831 | 0.3661 | 0.0009 | 0.0016 | 0.0029 | 0.0068 | 0.0201 | 0.0316 | 0.0289 | 0.0382 | 0.8689 | 8 | 10 | 12 | 16 | 37 | 86 | 182 | 353 | 594 | 0.1248 | 17.36 | 4.816 | 0.6022 | 99357.5 | 73300000 | 62400000000 | 58600000000000 | 0.4227 | 0.2238 | 0.0264 | 0.0016 | 0.1059 | 0.0050 | 0.1959 | 0.0402 | 0.1696 | 0.0969 | 0.1979 | 0.1765 | 0.1462 | 0.2004 | 0.0726 | 0.1356 | 0.0497 | 0.1265 | 0.0358 | 0.2174 | 0.0000 | 0.0002 | 0.0005 | 0.0004 | 0.0018 | 0.0011 | 0.0067 | 0.0062 | 0.0389 | 0.0323 | 0.0555 | 0.0517 | 0.0427 | 0.0407 | 0.0604 | 0.0544 | 0.7937 | 0.8129 | 0.0002 | 0.0007 | 0.0011 | 0.0010 | 0.0034 | 0.0033 | 0.0119 | 0.0117 | 0.0387 | 0.0431 | 0.0656 | 0.0654 | 0.0477 | 0.0528 | 0.0658 | 0.0696 | 0.7657 | 0.7523 | 0.0000 | 0.0006 | 0.0016 | 0.0095 | 0.0399 | 0.0611 | 0.0434 | 0.0640 | 0.7799 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1199 | 269 | | 6858 | 34380 | 182.5 | 52.85 | 124.86 | 199.10 | 122 | 141 | 154 | 165 | 177 | 190 | 204 | 222 | 256 | 0.0332 | 1142 | 0.787 | 31.00 | 8.06 | 3 | 0.0117 | 80 | 0.0011 | 37.84 | 7.176 | 0.1947 | 36107.4 | 7670000 | 1740000000 | 418000000000 | 0.4164 | 0.2188 | 0.0008 | 0.0000 | 0.0016 | 0.0003 | 0.0074 | 0.0003 | 0.0251 | 0.0031 | 0.0740 | 0.0238 | 0.1294 | 0.0417 | 0.1524 | 0.0466 | 0.1762 | 0.0732 | 0.4332 | 0.8108 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0034 | 0.0000 | 0.0103 | 0.0012 | 0.0321 | 0.0128 | 0.0530 | 0.0208 | 0.0614 | 0.0187 | 0.0821 | 0.0317 | 0.7569 | 0.9147 | 0.0035 | 0.0089 | 0.0090 | 0.0089 | 0.0097 | 0.0222 | 0.0520 | 0.0532 | 0.0929 | 0.1064 | 0.1283 | 0.1241 | 0.0999 | 0.1004 | 0.1200 | 0.1241 | 0.4847 | 0.4520 | 0.0016 | 0.0038 | 0.0074 | 0.0272 | 0.0579 | 0.0886 | 0.0908 | 0.1164 | 0.6063 | 17 | 21 | 25 | 29 | 35 | 48 | 91 | 194 | 364 | 0.0577 | 29.38 | 4.737 | 0.5383 | 55230.0 | 41200000 | 40500000000 | 47700000000000 | 0.3925 | 0.2378 | 0.1380 | 0.0050 | 0.3601 | 0.0465 | 0.2981 | 0.2724 | 0.1080 | 0.2297 | 0.0587 | 0.1914 | 0.0244 | 0.1219 | 0.0089 | 0.0649 | 0.0028 | 0.0419 | 0.0011 | 0.0263 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0019 | 0.0020 | 0.0186 | 0.0147 | 0.0758 | 0.0670 | 0.1162 | 0.0990 | 0.0798 | 0.0694 | 0.1195 | 0.1071 | 0.5878 | 0.6402 | 0.0002 | 0.0003 | 0.0007 | 0.0022 | 0.0033 | 0.0056 | 0.0256 | 0.0302 | 0.0905 | 0.0964 | 0.1439 | 0.1483 | 0.0934 | 0.1014 | 0.1314 | 0.1378 | 0.5108 | 0.4778 | 0.0002 | 0.0007 | 0.0022 | 0.0238 | 0.0786 | 0.1331 | 0.0854 | 0.1281 | 0.5480 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 334 | 363 | | 15302 | 41714 | 244.9 | 60.87 | 131.95 | 179.42 | 171 | 196 | 213 | 227 | 242 | 257 | 273 | 292 | 320 | 0.0338 | 1411 | 0.710 | 67.01 | 10.63 | 1 | 0.0092 | 141 | 0.0009 | 32.33 | 7.369 | 0.2155 | 63663.8 | 17500000 | 5040000000 | 1520000000000 | 0.3811 | 0.2520 | 0.0003 | 0.0001 | 0.0018 | 0.0001 | 0.0054 | 0.0012 | 0.0129 | 0.0025 | 0.0443 | 0.0131 | 0.0775 | 0.0277 | 0.0883 | 0.0259 | 0.1303 | 0.0318 | 0.6391 | 0.8975 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0005 | 0.0043 | 0.0006 | 0.0157 | 0.0082 | 0.0271 | 0.0149 | 0.0311 | 0.0107 | 0.0502 | 0.0147 | 0.8688 | 0.9504 | 0.0040 | 0.0021 | 0.0074 | 0.0094 | 0.0148 | 0.0178 | 0.0415 | 0.0545 | 0.0820 | 0.1027 | 0.1180 | 0.1394 | 0.0981 | 0.1038 | 0.1164 | 0.1153 | 0.5177 | 0.4549 | 0.0010 | 0.0043 | 0.0084 | 0.0193 | 0.0357 | 0.0673 | 0.0704 | 0.0887 | 0.7048 | 13 | 17 | 21 | 29 | 47 | 80 | 136 | 229 | 381 | 0.0427 | 30.07 | 5.192 | 0.5095 | 49598.6 | 28100000 | 20000000000 | 16800000000000 | 0.3211 | 0.3337 | 0.0612 | 0.0021 | 0.1948 | 0.0183 | 0.2759 | 0.1123 | 0.1692 | 0.1501 | 0.1266 | 0.2025 | 0.0897 | 0.1912 | 0.0381 | 0.1170 | 0.0295 | 0.0975 | 0.0151 | 0.1089 | 0.0001 | 0.0001 | 0.0003 | 0.0005 | 0.0017 | 0.0013 | 0.0140 | 0.0104 | 0.0568 | 0.0497 | 0.0959 | 0.0827 | 0.0647 | 0.0548 | 0.0965 | 0.0855 | 0.6699 | 0.7149 | 0.0002 | 0.0004 | 0.0005 | 0.0012 | 0.0029 | 0.0045 | 0.0170 | 0.0211 | 0.0778 | 0.0843 | 0.1185 | 0.1332 | 0.0800 | 0.0874 | 0.1208 | 0.1226 | 0.5822 | 0.5453 | 0.0002 | 0.0013 | 0.0024 | 0.0139 | 0.0650 | 0.1091 | 0.0726 | 0.1074 | 0.6281 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 241 | 848 | | 10173 | 33400 | 558.7 | 106.36 | 141.20 | 210.07 | 440 | 469 | 494 | 517 | 539 | 564 | 595 | 638 | 721 | 0.0340 | 1136 | 1.181 | 125.88 | 48.08 | 1 | 0.0321 | 327 | 0.0010 | 33.71 | 7.169 | 0.1994 | 323447.0 | 194000000 | 121000000000 | 78500000000000 | 0.3999 | 0.2475 | 0.0004 | 0.0002 | 0.0009 | 0.0001 | 0.0027 | 0.0002 | 0.0123 | 0.0021 | 0.0344 | 0.0148 | 0.0701 | 0.0282 | 0.0822 | 0.0219 | 0.1201 | 0.0283 | 0.6769 | 0.9042 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0077 | 0.0002 | 0.0193 | 0.0092 | 0.0401 | 0.0151 | 0.0464 | 0.0088 | 0.0651 | 0.0146 | 0.8195 | 0.9521 | 0.0060 | 0.0020 | 0.0079 | 0.0101 | 0.0113 | 0.0061 | 0.0344 | 0.0869 | 0.0656 | 0.1212 | 0.0947 | 0.2222 | 0.0742 | 0.1253 | 0.0947 | 0.1616 | 0.6113 | 0.2646 | 0.0019 | 0.0063 | 0.0137 | 0.0288 | 0.0574 | 0.1020 | 0.0876 | 0.1004 | 0.6019 | 7 | 9 | 12 | 16 | 31 | 71 | 144 | 264 | 446 | 0.0759 | 52.63 | 5.308 | 0.4892 | 64064.9 | 41000000 | 31800000000 | 28400000000000 | 0.3985 | 0.2299 | 0.1332 | 0.0028 | 0.3108 | 0.0481 | 0.2982 | 0.2452 | 0.1039 | 0.2139 | 0.0716 | 0.1845 | 0.0484 | 0.1328 | 0.0222 | 0.0737 | 0.0081 | 0.0576 | 0.0035 | 0.0413 | 0.0002 | 0.0002 | 0.0008 | 0.0002 | 0.0013 | 0.0007 | 0.0107 | 0.0085 | 0.0677 | 0.0583 | 0.1067 | 0.0940 | 0.0684 | 0.0620 | 0.1038 | 0.0989 | 0.6404 | 0.6771 | 0.0001 | 0.0001 | 0.0004 | 0.0005 | 0.0018 | 0.0038 | 0.0161 | 0.0195 | 0.0838 | 0.0907 | 0.1222 | 0.1354 | 0.0813 | 0.0869 | 0.1259 | 0.1305 | 0.5681 | 0.5326 | 0.0003 | 0.0006 | 0.0013 | 0.0134 | 0.0759 | 0.1150 | 0.0717 | 0.1123 | 0.6096 | ||
| MCF 10A | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 593 | 809 | | 9054 | 36760 | 386.6 | 78.38 | 181.80 | 168.48 | 283 | 319 | 345 | 368 | 389 | 408 | 428 | 453 | 485 | 0.0343 | 1261 | 1.172 | 117.32 | 46.07 | 2 | 0.0357 | 323 | 0.0013 | 28.99 | 6.930 | 0.2068 | 155613.0 | 64900000 | 28000000000 | 12400000000000 | 0.4514 | 0.1993 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0031 | 0.0000 | 0.0122 | 0.0006 | 0.0609 | 0.0126 | 0.1366 | 0.0323 | 0.1416 | 0.0335 | 0.1674 | 0.0533 | 0.4776 | 0.8677 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0025 | 0.0000 | 0.0256 | 0.0110 | 0.0577 | 0.0252 | 0.0556 | 0.0184 | 0.0717 | 0.0277 | 0.7858 | 0.9178 | 0.0076 | 0.0205 | 0.0124 | 0.1231 | 0.0275 | 0.0923 | 0.0927 | 0.1282 | 0.1683 | 0.1692 | 0.1999 | 0.1538 | 0.1484 | 0.0974 | 0.1374 | 0.1077 | 0.2060 | 0.1077 | 0.0006 | 0.0009 | 0.0039 | 0.0214 | 0.0744 | 0.1309 | 0.1084 | 0.1493 | 0.5102 | 20 | 40 | 70 | 101 | 134 | 175 | 226 | 293 | 410 | 0.0090 | 24.30 | 6.122 | 0.3733 | 61436.3 | 29700000 | 18600000000 | 14600000000000 | 0.4309 | 0.1918 | 0.0224 | 0.0007 | 0.1034 | 0.0058 | 0.2259 | 0.0487 | 0.1796 | 0.0900 | 0.1556 | 0.1611 | 0.1385 | 0.1955 | 0.0838 | 0.1496 | 0.0540 | 0.1427 | 0.0368 | 0.2058 | 0.0002 | 0.0003 | 0.0014 | 0.0006 | 0.0040 | 0.0027 | 0.0165 | 0.0104 | 0.0562 | 0.0443 | 0.1108 | 0.0905 | 0.0855 | 0.0719 | 0.1171 | 0.1021 | 0.6083 | 0.6773 | 0.0012 | 0.0016 | 0.0027 | 0.0043 | 0.0087 | 0.0124 | 0.0274 | 0.0393 | 0.0838 | 0.0961 | 0.1402 | 0.1499 | 0.1102 | 0.1133 | 0.1381 | 0.1378 | 0.4877 | 0.4453 | 0.0006 | 0.0015 | 0.0052 | 0.0174 | 0.0731 | 0.1259 | 0.1003 | 0.1286 | 0.5475 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 224 | 664 | | 23929 | 53243 | 235.7 | 71.53 | 198.53 | 308.24 | 140 | 172 | 197 | 217 | 235 | 254 | 274 | 298 | 328 | 0.0344 | 1829 | 0.641 | 165.59 | 39.45 | 7 | 0.0212 | 508 | 0.0005 | 51.67 | 7.813 | 0.1685 | 60653.4 | 16700000 | 4890000000 | 1500000000000 | 0.4168 | 0.2169 | 0.0013 | 0.0002 | 0.0025 | 0.0005 | 0.0085 | 0.0016 | 0.0313 | 0.0057 | 0.0797 | 0.0252 | 0.1433 | 0.0530 | 0.1429 | 0.0600 | 0.1764 | 0.0821 | 0.4142 | 0.7718 | 0.0006 | 0.0002 | 0.0010 | 0.0003 | 0.0020 | 0.0007 | 0.0074 | 0.0028 | 0.0227 | 0.0123 | 0.0429 | 0.0258 | 0.0415 | 0.0237 | 0.0600 | 0.0321 | 0.8218 | 0.9020 | 0.0018 | 0.0071 | 0.0045 | 0.0102 | 0.0154 | 0.0252 | 0.0432 | 0.0885 | 0.0873 | 0.1322 | 0.1280 | 0.1588 | 0.1107 | 0.1225 | 0.1340 | 0.1433 | 0.4752 | 0.3123 | 0.0008 | 0.0021 | 0.0061 | 0.0159 | 0.0445 | 0.0832 | 0.0794 | 0.1112 | 0.6569 | 15 | 19 | 23 | 31 | 50 | 98 | 191 | 331 | 581 | 0.0417 | 56.38 | 5.497 | 0.4839 | 134424.0 | 143000000 | 193000000000 | 306000000000000 | 0.3773 | 0.2809 | 0.0950 | 0.0031 | 0.2742 | 0.0340 | 0.2930 | 0.1903 | 0.1326 | 0.1923 | 0.0925 | 0.1954 | 0.0613 | 0.1542 | 0.0320 | 0.0969 | 0.0146 | 0.0718 | 0.0047 | 0.0620 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0028 | 0.0019 | 0.0151 | 0.0118 | 0.0675 | 0.0598 | 0.1124 | 0.0965 | 0.0779 | 0.0655 | 0.1108 | 0.0997 | 0.6126 | 0.6642 | 0.0005 | 0.0011 | 0.0017 | 0.0024 | 0.0055 | 0.0069 | 0.0244 | 0.0283 | 0.0804 | 0.0894 | 0.1332 | 0.1361 | 0.0938 | 0.0992 | 0.1210 | 0.1267 | 0.5395 | 0.5097 | 0.0004 | 0.0016 | 0.0031 | 0.0214 | 0.0760 | 0.1177 | 0.0887 | 0.1187 | 0.5725 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 503 | 432 | | 11808 | 33332 | 318.9 | 77.36 | 142.89 | 210.03 | 224 | 252 | 274 | 294 | 313 | 332 | 354 | 382 | 421 | 0.0347 | 1158 | 1.075 | 96.88 | 32.00 | 1 | 0.0204 | 241 | 0.0011 | 35.28 | 7.136 | 0.2018 | 107664.0 | 38400000 | 14400000000 | 5670000000000 | 0.4385 | 0.2096 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0068 | 0.0004 | 0.0240 | 0.0021 | 0.0823 | 0.0190 | 0.1435 | 0.0483 | 0.1432 | 0.0507 | 0.1608 | 0.0696 | 0.4388 | 0.8100 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0071 | 0.0012 | 0.0317 | 0.0115 | 0.0656 | 0.0250 | 0.0600 | 0.0226 | 0.0788 | 0.0331 | 0.7553 | 0.9064 | 0.0047 | 0.0040 | 0.0064 | 0.0162 | 0.0180 | 0.0324 | 0.0588 | 0.1309 | 0.1171 | 0.1646 | 0.1656 | 0.2146 | 0.1257 | 0.1242 | 0.1416 | 0.1026 | 0.3621 | 0.2105 | 0.0020 | 0.0023 | 0.0069 | 0.0236 | 0.0705 | 0.1235 | 0.0941 | 0.1163 | 0.5608 | 6 | 7 | 9 | 11 | 20 | 67 | 166 | 292 | 458 | 0.1413 | 28.98 | 4.701 | 0.5652 | 64528.1 | 40100000 | 31100000000 | 29500000000000 | 0.4198 | 0.2297 | 0.0409 | 0.0008 | 0.1490 | 0.0130 | 0.2877 | 0.0770 | 0.1876 | 0.1317 | 0.1496 | 0.1991 | 0.0863 | 0.2098 | 0.0489 | 0.1278 | 0.0334 | 0.1018 | 0.0167 | 0.1390 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0007 | 0.0046 | 0.0041 | 0.0332 | 0.0264 | 0.0586 | 0.0502 | 0.0443 | 0.0368 | 0.0677 | 0.0562 | 0.7904 | 0.8252 | 0.0000 | 0.0002 | 0.0003 | 0.0008 | 0.0015 | 0.0014 | 0.0069 | 0.0086 | 0.0446 | 0.0485 | 0.0792 | 0.0935 | 0.0610 | 0.0660 | 0.0897 | 0.0966 | 0.7168 | 0.6842 | 0.0000 | 0.0006 | 0.0008 | 0.0069 | 0.0372 | 0.0677 | 0.0539 | 0.0771 | 0.7557 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 162 | 234 | | 7241 | 33553 | 311.8 | 96.47 | 118.63 | 162.69 | 187 | 201 | 237 | 287 | 318 | 345 | 372 | 400 | 436 | 0.0350 | 1175 | 0.651 | 97.19 | 15.30 | 2 | 0.0305 | 221 | 0.0011 | 37.81 | 7.274 | 0.2128 | 106500.0 | 39100000 | 15200000000 | 6200000000000 | 0.4774 | 0.1776 | 0.0004 | 0.0012 | 0.0025 | 0.0024 | 0.0078 | 0.0057 | 0.0252 | 0.0134 | 0.0900 | 0.0431 | 0.1460 | 0.0745 | 0.1488 | 0.0709 | 0.1729 | 0.1150 | 0.4064 | 0.6737 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0012 | 0.0045 | 0.0020 | 0.0085 | 0.0163 | 0.0263 | 0.0285 | 0.0387 | 0.0281 | 0.0343 | 0.0386 | 0.0461 | 0.8853 | 0.8385 | 0.0024 | 0.0155 | 0.0043 | 0.0127 | 0.0119 | 0.0325 | 0.0396 | 0.0876 | 0.0835 | 0.1441 | 0.1098 | 0.1935 | 0.1150 | 0.1483 | 0.1394 | 0.1384 | 0.4940 | 0.2274 | 0.0000 | 0.0011 | 0.0029 | 0.0135 | 0.0296 | 0.0630 | 0.0643 | 0.0849 | 0.7407 | 9 | 11 | 14 | 19 | 34 | 73 | 138 | 222 | 342 | 0.1019 | 11.63 | 4.467 | 0.5909 | 40541.7 | 20200000 | 12600000000 | 9300000000000 | 0.3536 | 0.3217 | 0.0195 | 0.0035 | 0.1006 | 0.0081 | 0.1840 | 0.0477 | 0.1733 | 0.1043 | 0.1800 | 0.1722 | 0.1418 | 0.1779 | 0.1082 | 0.1344 | 0.0594 | 0.1368 | 0.0332 | 0.2151 | 0.0001 | 0.0006 | 0.0006 | 0.0005 | 0.0020 | 0.0011 | 0.0085 | 0.0076 | 0.0341 | 0.0295 | 0.0563 | 0.0485 | 0.0428 | 0.0362 | 0.0619 | 0.0541 | 0.7937 | 0.8219 | 0.0001 | 0.0002 | 0.0013 | 0.0015 | 0.0028 | 0.0035 | 0.0110 | 0.0135 | 0.0448 | 0.0478 | 0.0745 | 0.0869 | 0.0567 | 0.0645 | 0.0842 | 0.0980 | 0.7246 | 0.6843 | 0.0002 | 0.0009 | 0.0028 | 0.0099 | 0.0385 | 0.0629 | 0.0519 | 0.0705 | 0.7623 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 619 | 317 | | 7410 | 29983 | 364.7 | 86.29 | 152.06 | 265.97 | 260 | 289 | 313 | 336 | 358 | 380 | 405 | 434 | 477 | 0.0351 | 1051 | 1.206 | 108.37 | 43.84 | 1 | 0.0379 | 281 | 0.0006 | 87.06 | 7.645 | 0.1436 | 140416.0 | 57000000 | 24300000000 | 10900000000000 | 0.4464 | 0.2073 | 0.0005 | 0.0000 | 0.0018 | 0.0001 | 0.0086 | 0.0001 | 0.0271 | 0.0018 | 0.0873 | 0.0187 | 0.1534 | 0.0482 | 0.1532 | 0.0439 | 0.1846 | 0.0654 | 0.3836 | 0.8218 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0001 | 0.0081 | 0.0003 | 0.0365 | 0.0110 | 0.0711 | 0.0286 | 0.0684 | 0.0204 | 0.0949 | 0.0311 | 0.7198 | 0.9085 | 0.0050 | 0.0092 | 0.0093 | 0.0297 | 0.0328 | 0.0343 | 0.0734 | 0.0847 | 0.1290 | 0.1533 | 0.1917 | 0.2197 | 0.1226 | 0.1327 | 0.1347 | 0.1373 | 0.3015 | 0.1991 | 0.0006 | 0.0026 | 0.0110 | 0.0266 | 0.0747 | 0.1389 | 0.1155 | 0.1259 | 0.5043 | 7 | 9 | 11 | 13 | 20 | 43 | 110 | 258 | 517 | 0.1512 | 39.36 | 4.482 | 0.5817 | 93855.6 | 84800000 | 94200000000 | 120000000000000 | 0.4152 | 0.1980 | 0.0734 | 0.0021 | 0.2052 | 0.0259 | 0.2539 | 0.1687 | 0.1640 | 0.1542 | 0.1373 | 0.1932 | 0.0879 | 0.1763 | 0.0480 | 0.1107 | 0.0165 | 0.0824 | 0.0137 | 0.0866 | 0.0000 | 0.0002 | 0.0007 | 0.0005 | 0.0021 | 0.0003 | 0.0100 | 0.0059 | 0.0491 | 0.0469 | 0.0856 | 0.0756 | 0.0537 | 0.0477 | 0.0753 | 0.0702 | 0.7236 | 0.7526 | 0.0003 | 0.0001 | 0.0018 | 0.0006 | 0.0017 | 0.0025 | 0.0090 | 0.0096 | 0.0589 | 0.0634 | 0.0991 | 0.1035 | 0.0632 | 0.0706 | 0.0877 | 0.0978 | 0.6783 | 0.6519 | 0.0001 | 0.0011 | 0.0020 | 0.0119 | 0.0542 | 0.0904 | 0.0605 | 0.0819 | 0.6977 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 608 | 285 | | 12711 | 40214 | 295.5 | 67.78 | 143.73 | 163.15 | 209 | 239 | 260 | 277 | 293 | 309 | 328 | 350 | 384 | 0.0353 | 1418 | 1.016 | 119.62 | 46.69 | 2 | 0.0271 | 344 | 0.0013 | 26.32 | 6.921 | 0.2277 | 91894.8 | 30000000 | 10200000000 | 3620000000000 | 0.4370 | 0.2187 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0043 | 0.0006 | 0.0194 | 0.0020 | 0.0643 | 0.0160 | 0.1388 | 0.0422 | 0.1306 | 0.0429 | 0.1606 | 0.0610 | 0.4809 | 0.8354 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0053 | 0.0011 | 0.0274 | 0.0105 | 0.0590 | 0.0245 | 0.0510 | 0.0194 | 0.0701 | 0.0291 | 0.7861 | 0.9154 | 0.0071 | 0.0128 | 0.0075 | 0.0192 | 0.0179 | 0.0417 | 0.0613 | 0.1330 | 0.1289 | 0.1875 | 0.1811 | 0.2051 | 0.1097 | 0.0865 | 0.1506 | 0.1330 | 0.3358 | 0.1811 | 0.0008 | 0.0024 | 0.0064 | 0.0265 | 0.0750 | 0.1260 | 0.1010 | 0.1299 | 0.5321 | 11 | 17 | 28 | 49 | 80 | 122 | 178 | 254 | 371 | 0.0435 | 17.85 | 5.232 | 0.4864 | 47276.4 | 22300000 | 13100000000 | 8910000000000 | 0.4347 | 0.1843 | 0.0559 | 0.0013 | 0.1725 | 0.0173 | 0.2681 | 0.1183 | 0.1475 | 0.1465 | 0.1431 | 0.1771 | 0.0944 | 0.1809 | 0.0533 | 0.1241 | 0.0376 | 0.1058 | 0.0276 | 0.1288 | 0.0001 | 0.0001 | 0.0004 | 0.0006 | 0.0019 | 0.0015 | 0.0116 | 0.0097 | 0.0649 | 0.0509 | 0.1109 | 0.0898 | 0.0752 | 0.0672 | 0.1098 | 0.0956 | 0.6253 | 0.6846 | 0.0006 | 0.0007 | 0.0011 | 0.0013 | 0.0036 | 0.0075 | 0.0213 | 0.0276 | 0.0840 | 0.0988 | 0.1417 | 0.1531 | 0.0910 | 0.0952 | 0.1254 | 0.1330 | 0.5313 | 0.4828 | 0.0003 | 0.0013 | 0.0032 | 0.0164 | 0.0787 | 0.1225 | 0.0861 | 0.1208 | 0.5707 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 776 | 533 | | 11980 | 33861 | 383.5 | 82.50 | 120.63 | 176.56 | 283 | 310 | 334 | 355 | 376 | 398 | 421 | 451 | 496 | 0.0356 | 1205 | 1.136 | 140.66 | 55.15 | 1 | 0.0313 | 375 | 0.0009 | 37.01 | 7.234 | 0.1929 | 153867.0 | 64500000 | 28200000000 | 12800000000000 | 0.4493 | 0.2003 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0182 | 0.0008 | 0.0630 | 0.0134 | 0.1320 | 0.0320 | 0.1379 | 0.0333 | 0.1599 | 0.0519 | 0.4853 | 0.8686 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0010 | 0.0000 | 0.0076 | 0.0001 | 0.0277 | 0.0090 | 0.0540 | 0.0170 | 0.0581 | 0.0126 | 0.0745 | 0.0212 | 0.7764 | 0.9401 | 0.0019 | 0.0113 | 0.0047 | 0.0244 | 0.0159 | 0.0357 | 0.0637 | 0.1429 | 0.1404 | 0.1560 | 0.1807 | 0.2237 | 0.1147 | 0.0977 | 0.1470 | 0.1278 | 0.3310 | 0.1805 | 0.0004 | 0.0018 | 0.0069 | 0.0208 | 0.0738 | 0.1090 | 0.1005 | 0.1337 | 0.5532 | 7 | 8 | 10 | 13 | 28 | 71 | 135 | 223 | 358 | 0.1025 | 9.69 | 4.335 | 0.5557 | 45723.5 | 25300000 | 17600000000 | 14200000000000 | 0.3892 | 0.2409 | 0.0580 | 0.0013 | 0.2129 | 0.0223 | 0.2772 | 0.1129 | 0.1731 | 0.1468 | 0.1215 | 0.2079 | 0.0876 | 0.1983 | 0.0398 | 0.1203 | 0.0207 | 0.0982 | 0.0093 | 0.0921 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0008 | 0.0004 | 0.0071 | 0.0056 | 0.0520 | 0.0410 | 0.0868 | 0.0707 | 0.0678 | 0.0584 | 0.0917 | 0.0804 | 0.6937 | 0.7434 | 0.0005 | 0.0002 | 0.0012 | 0.0009 | 0.0018 | 0.0021 | 0.0154 | 0.0152 | 0.0663 | 0.0760 | 0.1097 | 0.1251 | 0.0819 | 0.0859 | 0.1104 | 0.1159 | 0.6128 | 0.5786 | 0.0001 | 0.0003 | 0.0013 | 0.0107 | 0.0581 | 0.1011 | 0.0739 | 0.1012 | 0.6533 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 517 | 209 | | 10942 | 35449 | 447.3 | 110.82 | 142.08 | 205.96 | 312 | 350 | 381 | 410 | 439 | 469 | 501 | 538 | 598 | 0.0363 | 1286 | 0.903 | 94.01 | 21.02 | 3 | 0.0206 | 225 | 0.0006 | 67.31 | 7.714 | 0.1503 | 212393.0 | 107000000 | 56200000000 | 31100000000000 | 0.4346 | 0.2214 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0003 | 0.0220 | 0.0020 | 0.0807 | 0.0222 | 0.1586 | 0.0494 | 0.1521 | 0.0568 | 0.1699 | 0.0831 | 0.4104 | 0.7861 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0069 | 0.0010 | 0.0331 | 0.0142 | 0.0664 | 0.0263 | 0.0584 | 0.0248 | 0.0766 | 0.0387 | 0.7570 | 0.8948 | 0.0022 | 0.0069 | 0.0081 | 0.0139 | 0.0103 | 0.0416 | 0.0550 | 0.1150 | 0.1279 | 0.1967 | 0.1699 | 0.1884 | 0.1225 | 0.1177 | 0.1516 | 0.1399 | 0.3524 | 0.1801 | 0.0008 | 0.0008 | 0.0065 | 0.0223 | 0.0687 | 0.1106 | 0.0929 | 0.1244 | 0.5730 | 7 | 10 | 12 | 15 | 24 | 71 | 163 | 276 | 443 | 0.1042 | 31.77 | 4.906 | 0.5483 | 62607.4 | 38100000 | 28100000000 | 23900000000000 | 0.4712 | 0.1726 | 0.0362 | 0.0022 | 0.1614 | 0.0112 | 0.2304 | 0.0744 | 0.1585 | 0.1487 | 0.1473 | 0.1922 | 0.1121 | 0.1786 | 0.0662 | 0.1198 | 0.0498 | 0.1135 | 0.0382 | 0.1594 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0067 | 0.0061 | 0.0345 | 0.0311 | 0.0658 | 0.0530 | 0.0462 | 0.0389 | 0.0718 | 0.0600 | 0.7738 | 0.8102 | 0.0000 | 0.0005 | 0.0006 | 0.0007 | 0.0010 | 0.0021 | 0.0102 | 0.0107 | 0.0492 | 0.0560 | 0.0855 | 0.0946 | 0.0637 | 0.0738 | 0.0966 | 0.1019 | 0.6933 | 0.6595 | 0.0002 | 0.0003 | 0.0018 | 0.0074 | 0.0431 | 0.0740 | 0.0560 | 0.0876 | 0.7297 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 700 | | 12030 | 35050 | 359.5 | 76.99 | 172.29 | 212.34 | 266 | 289 | 311 | 331 | 350 | 372 | 398 | 428 | 469 | 0.0370 | 1298 | 1.080 | 120.07 | 37.70 | 1 | 0.0246 | 296 | 0.0007 | 42.37 | 7.437 | 0.1770 | 135186.0 | 53100000 | 21700000000 | 9200000000000 | 0.4257 | 0.2254 | 0.0007 | 0.0000 | 0.0024 | 0.0001 | 0.0047 | 0.0001 | 0.0166 | 0.0019 | 0.0578 | 0.0130 | 0.1117 | 0.0286 | 0.1278 | 0.0293 | 0.1729 | 0.0489 | 0.5054 | 0.8782 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0021 | 0.0000 | 0.0074 | 0.0004 | 0.0263 | 0.0079 | 0.0509 | 0.0166 | 0.0541 | 0.0114 | 0.0771 | 0.0203 | 0.7814 | 0.9434 | 0.0031 | 0.0144 | 0.0096 | 0.0431 | 0.0206 | 0.0431 | 0.0477 | 0.1150 | 0.0984 | 0.1889 | 0.1164 | 0.1725 | 0.1067 | 0.1376 | 0.1474 | 0.1212 | 0.4501 | 0.1643 | 0.0022 | 0.0027 | 0.0087 | 0.0265 | 0.0634 | 0.0961 | 0.0890 | 0.1053 | 0.6061 | 8 | 10 | 16 | 35 | 74 | 134 | 219 | 336 | 490 | 0.0515 | 30.59 | 5.525 | 0.4509 | 74768.6 | 43400000 | 30000000000 | 23500000000000 | 0.4088 | 0.2228 | 0.0812 | 0.0029 | 0.2274 | 0.0275 | 0.2491 | 0.1801 | 0.1201 | 0.1627 | 0.1228 | 0.1764 | 0.0750 | 0.1525 | 0.0533 | 0.1018 | 0.0392 | 0.0801 | 0.0320 | 0.1161 | 0.0001 | 0.0001 | 0.0002 | 0.0004 | 0.0010 | 0.0009 | 0.0095 | 0.0074 | 0.0610 | 0.0504 | 0.1018 | 0.0884 | 0.0671 | 0.0617 | 0.1083 | 0.0895 | 0.6509 | 0.7012 | 0.0002 | 0.0002 | 0.0005 | 0.0005 | 0.0022 | 0.0037 | 0.0162 | 0.0203 | 0.0769 | 0.0888 | 0.1277 | 0.1338 | 0.0832 | 0.0898 | 0.1251 | 0.1318 | 0.5682 | 0.5312 | 0.0003 | 0.0002 | 0.0015 | 0.0144 | 0.0678 | 0.1109 | 0.0804 | 0.1157 | 0.6087 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 854 | 405 | | 7527 | 31665 | 388.4 | 72.66 | 93.45 | 141.02 | 301 | 326 | 347 | 364 | 382 | 400 | 421 | 447 | 487 | 0.0374 | 1185 | 1.088 | 108.58 | 28.32 | 1 | 0.0323 | 243 | 0.0008 | 48.68 | 7.360 | 0.1631 | 156148.0 | 64900000 | 27900000000 | 12400000000000 | 0.4021 | 0.2480 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0046 | 0.0001 | 0.0110 | 0.0014 | 0.0414 | 0.0136 | 0.1010 | 0.0353 | 0.0993 | 0.0248 | 0.1508 | 0.0388 | 0.5912 | 0.8859 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0001 | 0.0052 | 0.0005 | 0.0195 | 0.0099 | 0.0510 | 0.0234 | 0.0462 | 0.0107 | 0.0737 | 0.0159 | 0.8031 | 0.9394 | 0.0056 | 0.0138 | 0.0130 | 0.0826 | 0.0241 | 0.0872 | 0.0519 | 0.1193 | 0.1270 | 0.1560 | 0.1724 | 0.2294 | 0.1233 | 0.0917 | 0.1483 | 0.0734 | 0.3346 | 0.1468 | 0.0008 | 0.0025 | 0.0065 | 0.0239 | 0.0686 | 0.1113 | 0.0975 | 0.1231 | 0.5659 | 6 | 8 | 11 | 21 | 39 | 63 | 99 | 156 | 250 | 0.0635 | 9.53 | 4.513 | 0.5426 | 28619.4 | 17100000 | 15800000000 | 18600000000000 | 0.4450 | 0.1844 | 0.0328 | 0.0005 | 0.1395 | 0.0088 | 0.2204 | 0.0603 | 0.1624 | 0.1175 | 0.1549 | 0.1747 | 0.1262 | 0.2022 | 0.0836 | 0.1486 | 0.0471 | 0.1229 | 0.0331 | 0.1645 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0022 | 0.0027 | 0.0119 | 0.0124 | 0.0537 | 0.0399 | 0.0815 | 0.0673 | 0.0674 | 0.0542 | 0.0954 | 0.0807 | 0.6869 | 0.7423 | 0.0007 | 0.0007 | 0.0017 | 0.0008 | 0.0046 | 0.0050 | 0.0176 | 0.0205 | 0.0658 | 0.0826 | 0.1195 | 0.1283 | 0.0762 | 0.0818 | 0.1160 | 0.1209 | 0.5979 | 0.5594 | 0.0003 | 0.0015 | 0.0051 | 0.0174 | 0.0607 | 0.0986 | 0.0754 | 0.1077 | 0.6333 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 382 | 242 | | 12664 | 34586 | 373.4 | 98.30 | 213.98 | 284.63 | 263 | 291 | 313 | 335 | 358 | 382 | 408 | 446 | 511 | 0.0376 | 1299 | 0.766 | 102.08 | 31.62 | 1 | 0.0237 | 300 | 0.0005 | 74.63 | 7.800 | 0.1485 | 149085.0 | 63700000 | 29200000000 | 14200000000000 | 0.4340 | 0.2186 | 0.0003 | 0.0001 | 0.0035 | 0.0000 | 0.0057 | 0.0011 | 0.0212 | 0.0027 | 0.0752 | 0.0188 | 0.1495 | 0.0375 | 0.1557 | 0.0407 | 0.1833 | 0.0594 | 0.4057 | 0.8397 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0071 | 0.0004 | 0.0383 | 0.0102 | 0.0764 | 0.0200 | 0.0727 | 0.0183 | 0.1055 | 0.0299 | 0.6974 | 0.9212 | 0.0052 | 0.0055 | 0.0048 | 0.0036 | 0.0180 | 0.0155 | 0.0557 | 0.0675 | 0.0894 | 0.1150 | 0.1198 | 0.1359 | 0.0802 | 0.1004 | 0.1066 | 0.1305 | 0.5202 | 0.4261 | 0.0011 | 0.0038 | 0.0108 | 0.0345 | 0.0819 | 0.1264 | 0.0936 | 0.1140 | 0.5339 | 10 | 14 | 21 | 42 | 78 | 144 | 249 | 393 | 629 | 0.0536 | 36.30 | 5.670 | 0.4778 | 126798.0 | 105000000 | 105000000000 | 118000000000000 | 0.3874 | 0.2464 | 0.0531 | 0.0011 | 0.1879 | 0.0093 | 0.2767 | 0.0927 | 0.1677 | 0.1537 | 0.1237 | 0.2297 | 0.0869 | 0.1936 | 0.0497 | 0.1194 | 0.0326 | 0.0973 | 0.0216 | 0.1031 | 0.0002 | 0.0002 | 0.0003 | 0.0005 | 0.0015 | 0.0010 | 0.0112 | 0.0071 | 0.0544 | 0.0452 | 0.0794 | 0.0732 | 0.0619 | 0.0524 | 0.0887 | 0.0799 | 0.7024 | 0.7405 | 0.0007 | 0.0001 | 0.0007 | 0.0009 | 0.0015 | 0.0024 | 0.0132 | 0.0185 | 0.0721 | 0.0749 | 0.1034 | 0.1143 | 0.0693 | 0.0766 | 0.1068 | 0.1115 | 0.6324 | 0.6008 | 0.0003 | 0.0004 | 0.0017 | 0.0125 | 0.0632 | 0.0921 | 0.0646 | 0.0980 | 0.6673 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 141 | 279 | | 6550 | 28560 | 325.2 | 76.94 | 118.00 | 205.38 | 229 | 259 | 281 | 299 | 318 | 339 | 361 | 391 | 431 | 0.0380 | 1086 | 1.019 | 88.10 | 26.68 | 3 | 0.0337 | 221 | 0.0007 | 63.80 | 7.487 | 0.1467 | 111704.0 | 40400000 | 15300000000 | 6070000000000 | 0.4422 | 0.2121 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0067 | 0.0012 | 0.0248 | 0.0030 | 0.0781 | 0.0206 | 0.1554 | 0.0495 | 0.1682 | 0.0513 | 0.1992 | 0.0834 | 0.3659 | 0.7909 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0003 | 0.0069 | 0.0006 | 0.0339 | 0.0127 | 0.0714 | 0.0286 | 0.0678 | 0.0219 | 0.0992 | 0.0413 | 0.7200 | 0.8945 | 0.0053 | 0.0096 | 0.0114 | 0.0288 | 0.0220 | 0.0745 | 0.0676 | 0.0962 | 0.1277 | 0.1923 | 0.1634 | 0.1635 | 0.1087 | 0.1130 | 0.1664 | 0.1394 | 0.3275 | 0.1827 | 0.0010 | 0.0043 | 0.0085 | 0.0299 | 0.0768 | 0.1404 | 0.1063 | 0.1358 | 0.4970 | 7 | 9 | 10 | 12 | 16 | 29 | 83 | 200 | 398 | 0.1579 | 24.15 | 4.168 | 0.5959 | 56105.0 | 38900000 | 32800000000 | 31500000000000 | 0.4719 | 0.1982 | 0.0778 | 0.0031 | 0.2645 | 0.0291 | 0.3497 | 0.1507 | 0.1482 | 0.1884 | 0.0819 | 0.2342 | 0.0426 | 0.1740 | 0.0180 | 0.0983 | 0.0098 | 0.0746 | 0.0074 | 0.0478 | 0.0000 | 0.0001 | 0.0004 | 0.0002 | 0.0004 | 0.0003 | 0.0067 | 0.0067 | 0.0467 | 0.0397 | 0.0880 | 0.0720 | 0.0536 | 0.0512 | 0.0899 | 0.0787 | 0.7143 | 0.7511 | 0.0001 | 0.0003 | 0.0004 | 0.0012 | 0.0016 | 0.0016 | 0.0092 | 0.0145 | 0.0557 | 0.0597 | 0.1096 | 0.1123 | 0.0663 | 0.0794 | 0.1060 | 0.1115 | 0.6510 | 0.6194 | 0.0000 | 0.0001 | 0.0019 | 0.0094 | 0.0525 | 0.0917 | 0.0654 | 0.0947 | 0.6842 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 949 | 842 | | 9889 | 31538 | 604.3 | 116.89 | 203.51 | 321.81 | 475 | 511 | 538 | 562 | 585 | 611 | 645 | 691 | 761 | 0.0383 | 1208 | 0.571 | 106.00 | 25.06 | 1 | 0.0342 | 338 | 0.0006 | 73.38 | 7.682 | 0.1588 | 378894.0 | 247000000 | 168000000000 | 119000000000000 | 0.4171 | 0.2369 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0004 | 0.0074 | 0.0013 | 0.0446 | 0.0124 | 0.0828 | 0.0265 | 0.0975 | 0.0233 | 0.1253 | 0.0331 | 0.6398 | 0.9031 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0005 | 0.0001 | 0.0032 | 0.0003 | 0.0237 | 0.0085 | 0.0410 | 0.0170 | 0.0490 | 0.0098 | 0.0664 | 0.0157 | 0.8162 | 0.9485 | 0.0014 | 0.0049 | 0.0084 | 0.0172 | 0.0274 | 0.0197 | 0.0556 | 0.1032 | 0.0985 | 0.1106 | 0.1343 | 0.1548 | 0.1069 | 0.1253 | 0.1153 | 0.1327 | 0.4522 | 0.3317 | 0.0012 | 0.0036 | 0.0092 | 0.0412 | 0.0736 | 0.1091 | 0.0992 | 0.1165 | 0.5465 | 8 | 9 | 12 | 17 | 48 | 103 | 192 | 355 | 647 | 0.1118 | 47.39 | 5.112 | 0.5378 | 144975.0 | 152000000 | 200000000000 | 309000000000000 | 0.3985 | 0.2132 | 0.0695 | 0.0027 | 0.2144 | 0.0263 | 0.2470 | 0.1596 | 0.1348 | 0.1210 | 0.1242 | 0.1636 | 0.0801 | 0.1770 | 0.0595 | 0.1103 | 0.0374 | 0.0928 | 0.0331 | 0.1466 | 0.0000 | 0.0001 | 0.0006 | 0.0005 | 0.0010 | 0.0014 | 0.0081 | 0.0074 | 0.0606 | 0.0447 | 0.0939 | 0.0785 | 0.0610 | 0.0514 | 0.0947 | 0.0842 | 0.6801 | 0.7319 | 0.0001 | 0.0003 | 0.0006 | 0.0005 | 0.0012 | 0.0012 | 0.0163 | 0.0192 | 0.0766 | 0.0837 | 0.1158 | 0.1356 | 0.0765 | 0.0760 | 0.1122 | 0.1199 | 0.6007 | 0.5636 | 0.0002 | 0.0005 | 0.0013 | 0.0122 | 0.0687 | 0.1051 | 0.0681 | 0.1068 | 0.6370 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 767 | 375 | | 10994 | 36702 | 317.2 | 66.33 | 88.78 | 117.60 | 238 | 259 | 276 | 292 | 309 | 327 | 346 | 373 | 410 | 0.0385 | 1412 | 0.777 | 113.02 | 23.02 | 1 | 0.0226 | 249 | 0.0006 | 70.27 | 7.726 | 0.1479 | 104984.0 | 36300000 | 13000000000 | 4880000000000 | 0.4228 | 0.2250 | 0.0003 | 0.0000 | 0.0008 | 0.0001 | 0.0038 | 0.0001 | 0.0125 | 0.0008 | 0.0612 | 0.0134 | 0.1259 | 0.0305 | 0.1295 | 0.0324 | 0.1666 | 0.0567 | 0.4994 | 0.8660 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0062 | 0.0003 | 0.0265 | 0.0088 | 0.0510 | 0.0177 | 0.0541 | 0.0124 | 0.0766 | 0.0239 | 0.7828 | 0.9370 | 0.0031 | 0.0102 | 0.0078 | 0.0225 | 0.0225 | 0.0758 | 0.0628 | 0.1250 | 0.1313 | 0.1557 | 0.1763 | 0.1475 | 0.1104 | 0.1025 | 0.1423 | 0.1270 | 0.3433 | 0.2336 | 0.0010 | 0.0030 | 0.0062 | 0.0294 | 0.0726 | 0.1184 | 0.1031 | 0.1345 | 0.5318 | 10 | 12 | 14 | 19 | 32 | 55 | 97 | 156 | 255 | 0.0788 | 13.52 | 4.639 | 0.5538 | 21712.5 | 8010000 | 3800000000 | 2180000000000 | 0.4103 | 0.2154 | 0.0637 | 0.0009 | 0.2390 | 0.0098 | 0.3525 | 0.1068 | 0.1643 | 0.1924 | 0.0959 | 0.2534 | 0.0480 | 0.2004 | 0.0216 | 0.1040 | 0.0113 | 0.0742 | 0.0037 | 0.0580 | 0.0002 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0012 | 0.0109 | 0.0097 | 0.0639 | 0.0507 | 0.0964 | 0.0843 | 0.0715 | 0.0616 | 0.1087 | 0.0931 | 0.6473 | 0.6989 | 0.0002 | 0.0004 | 0.0011 | 0.0016 | 0.0034 | 0.0043 | 0.0175 | 0.0189 | 0.0814 | 0.0927 | 0.1222 | 0.1338 | 0.0853 | 0.0887 | 0.1273 | 0.1253 | 0.5616 | 0.5343 | 0.0001 | 0.0004 | 0.0016 | 0.0110 | 0.0724 | 0.1147 | 0.0774 | 0.1169 | 0.6055 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1048 | 708 | | 5142 | 24738 | 301.9 | 68.07 | 109.84 | 172.01 | 222 | 242 | 260 | 277 | 294 | 311 | 331 | 357 | 392 | 0.0388 | 959 | 0.968 | 116.28 | 25.18 | 1 | 0.0492 | 253 | 0.0006 | 71.96 | 7.550 | 0.1408 | 95756.4 | 31900000 | 11200000000 | 4100000000000 | 0.4570 | 0.1935 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0047 | 0.0000 | 0.0216 | 0.0019 | 0.0748 | 0.0214 | 0.1430 | 0.0387 | 0.1596 | 0.0406 | 0.1790 | 0.0601 | 0.4156 | 0.8373 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0082 | 0.0000 | 0.0378 | 0.0149 | 0.0692 | 0.0253 | 0.0736 | 0.0188 | 0.0862 | 0.0339 | 0.7226 | 0.9070 | 0.0043 | 0.0069 | 0.0096 | 0.0069 | 0.0246 | 0.0138 | 0.0769 | 0.0897 | 0.1143 | 0.1655 | 0.1357 | 0.1483 | 0.1026 | 0.1621 | 0.1303 | 0.1345 | 0.4017 | 0.2724 | 0.0009 | 0.0009 | 0.0082 | 0.0359 | 0.0848 | 0.1107 | 0.1086 | 0.1302 | 0.5199 | 8 | 9 | 10 | 12 | 15 | 23 | 92 | 222 | 376 | 0.2071 | 21.28 | 4.079 | 0.6284 | 41652.0 | 21000000 | 12200000000 | 7930000000000 | 0.5079 | 0.1266 | 0.0955 | 0.0067 | 0.2888 | 0.0516 | 0.2966 | 0.2331 | 0.1382 | 0.1992 | 0.0843 | 0.1815 | 0.0618 | 0.1415 | 0.0247 | 0.0705 | 0.0079 | 0.0494 | 0.0022 | 0.0666 | 0.0000 | 0.0001 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0081 | 0.0081 | 0.0426 | 0.0385 | 0.0742 | 0.0621 | 0.0481 | 0.0470 | 0.0763 | 0.0643 | 0.7492 | 0.7792 | 0.0003 | 0.0005 | 0.0011 | 0.0016 | 0.0032 | 0.0042 | 0.0113 | 0.0130 | 0.0493 | 0.0504 | 0.0852 | 0.0895 | 0.0569 | 0.0606 | 0.0833 | 0.0935 | 0.7095 | 0.6868 | 0.0003 | 0.0007 | 0.0018 | 0.0119 | 0.0426 | 0.0802 | 0.0555 | 0.0798 | 0.7272 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 800 | 501 | | 13792 | 38751 | 266.6 | 61.19 | 169.99 | 277.73 | 192 | 219 | 237 | 253 | 267 | 281 | 297 | 317 | 345 | 0.0391 | 1515 | 0.913 | 98.60 | 27.17 | 6 | 0.0188 | 259 | 0.0012 | 28.43 | 7.043 | 0.2221 | 74836.6 | 21900000 | 6660000000 | 2090000000000 | 0.4163 | 0.2227 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0034 | 0.0004 | 0.0145 | 0.0030 | 0.0508 | 0.0123 | 0.1000 | 0.0294 | 0.1083 | 0.0291 | 0.1428 | 0.0414 | 0.5789 | 0.8845 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0002 | 0.0051 | 0.0012 | 0.0181 | 0.0073 | 0.0381 | 0.0171 | 0.0415 | 0.0105 | 0.0570 | 0.0160 | 0.8387 | 0.9478 | 0.0032 | 0.0074 | 0.0083 | 0.0315 | 0.0221 | 0.0612 | 0.0437 | 0.1169 | 0.1095 | 0.1818 | 0.1536 | 0.1892 | 0.1312 | 0.1373 | 0.1276 | 0.1150 | 0.4009 | 0.1596 | 0.0001 | 0.0023 | 0.0069 | 0.0225 | 0.0520 | 0.0995 | 0.0920 | 0.1141 | 0.6107 | 11 | 14 | 16 | 21 | 32 | 62 | 139 | 285 | 553 | 0.1524 | 25.56 | 4.437 | 0.6078 | 106029.0 | 97600000 | 110000000000 | 141000000000000 | 0.3354 | 0.3305 | 0.0662 | 0.0027 | 0.2254 | 0.0240 | 0.2667 | 0.1419 | 0.1607 | 0.1818 | 0.1295 | 0.1818 | 0.0830 | 0.1829 | 0.0379 | 0.1071 | 0.0230 | 0.0916 | 0.0077 | 0.0861 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0035 | 0.0021 | 0.0193 | 0.0153 | 0.0582 | 0.0549 | 0.0728 | 0.0726 | 0.0478 | 0.0442 | 0.0766 | 0.0719 | 0.7205 | 0.7381 | 0.0006 | 0.0007 | 0.0019 | 0.0018 | 0.0059 | 0.0059 | 0.0221 | 0.0258 | 0.0548 | 0.0602 | 0.0841 | 0.0861 | 0.0579 | 0.0644 | 0.0867 | 0.0924 | 0.6859 | 0.6628 | 0.0003 | 0.0015 | 0.0047 | 0.0221 | 0.0559 | 0.0766 | 0.0542 | 0.0790 | 0.7058 |