High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 814 | | 2851 | 8407 | 391.9 | 153.08 | 40.60 | 64.74 | 211 | 237 | 264 | 302 | 359 | 440 | 510 | 564 | 609 | 0.0793 | 667 | 0.638 | 88.07 | 16.49 | 5 | 0.0831 | 237 | 0.0014 | 33.60 | 6.853 | 0.2650 | 176986.0 | 88700000 | 47600000000 | 26700000000000 | 0.3694 | 0.2467 | 0.0017 | 0.0000 | 0.0000 | 0.0018 | 0.0198 | 0.0037 | 0.0594 | 0.0117 | 0.2228 | 0.0608 | 0.2475 | 0.1148 | 0.1320 | 0.0853 | 0.1254 | 0.1160 | 0.1914 | 0.6059 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0025 | 0.0004 | 0.0061 | 0.0056 | 0.0386 | 0.0265 | 0.0570 | 0.0521 | 0.0404 | 0.0348 | 0.0545 | 0.0465 | 0.8009 | 0.8341 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0019 | 0.0059 | 0.0049 | 0.0208 | 0.0507 | 0.0639 | 0.0789 | 0.0906 | 0.0478 | 0.0743 | 0.0741 | 0.1055 | 0.7417 | 0.6360 | 0.0000 | 0.0000 | 0.0000 | 0.0054 | 0.0430 | 0.0675 | 0.0453 | 0.0606 | 0.7782 | 8 | 10 | 11 | 13 | 15 | 18 | 24 | 42 | 117 | 0.0814 | 2.85 | 3.639 | 0.6573 | 5839.4 | 1330000 | 353000000 | 100000000000 | 0.5410 | 0.1261 | 0.0144 | 0.0101 | 0.0804 | 0.0340 | 0.1835 | 0.0451 | 0.1773 | 0.0975 | 0.1567 | 0.1408 | 0.1649 | 0.1638 | 0.1113 | 0.1408 | 0.0804 | 0.1435 | 0.0309 | 0.2245 | 0.0015 | 0.0040 | 0.0060 | 0.0136 | 0.0144 | 0.0100 | 0.0194 | 0.0244 | 0.0557 | 0.0505 | 0.0815 | 0.0765 | 0.0532 | 0.0589 | 0.0820 | 0.0885 | 0.6864 | 0.6735 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0033 | 0.0050 | 0.0196 | 0.0177 | 0.0629 | 0.0703 | 0.0812 | 0.0809 | 0.0583 | 0.0596 | 0.0799 | 0.0852 | 0.6935 | 0.6806 | 0.0034 | 0.0040 | 0.0017 | 0.0166 | 0.0625 | 0.0763 | 0.0539 | 0.0878 | 0.6936 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 811 | 224 | | 3862 | 6781 | 328.4 | 152.30 | 138.02 | 238.95 | 140 | 175 | 209 | 260 | 309 | 370 | 436 | 481 | 535 | 0.0967 | 656 | 1.166 | 181.47 | 58.73 | 2 | 0.1144 | 442 | 0.0022 | 6.00 | 6.354 | 0.3863 | 131046.0 | 59300000 | 29000000000 | 15000000000000 | 0.3371 | 0.2738 | 0.0023 | 0.0005 | 0.0000 | 0.0011 | 0.0046 | 0.0043 | 0.0230 | 0.0097 | 0.0908 | 0.0500 | 0.1517 | 0.0844 | 0.1287 | 0.0580 | 0.1356 | 0.0876 | 0.4632 | 0.7045 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0048 | 0.0007 | 0.0205 | 0.0209 | 0.0301 | 0.0301 | 0.0261 | 0.0195 | 0.0305 | 0.0280 | 0.8872 | 0.9005 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0007 | 0.0052 | 0.0091 | 0.0207 | 0.0252 | 0.0342 | 0.0379 | 0.0726 | 0.0344 | 0.0654 | 0.0456 | 0.0840 | 0.8471 | 0.7168 | 0.0000 | 0.0000 | 0.0022 | 0.0039 | 0.0257 | 0.0363 | 0.0262 | 0.0312 | 0.8745 | 11 | 14 | 19 | 24 | 34 | 55 | 99 | 200 | 413 | 0.0754 | 21.49 | 4.311 | 0.6192 | 76139.6 | 68600000 | 77600000000 | 100000000000000 | 0.5118 | 0.1375 | 0.0101 | 0.0061 | 0.0553 | 0.0073 | 0.1508 | 0.0340 | 0.1508 | 0.0643 | 0.2462 | 0.1541 | 0.1683 | 0.2184 | 0.0955 | 0.1311 | 0.0628 | 0.1226 | 0.0603 | 0.2621 | 0.0000 | 0.0014 | 0.0021 | 0.0023 | 0.0057 | 0.0027 | 0.0114 | 0.0099 | 0.0532 | 0.0537 | 0.0749 | 0.0722 | 0.0583 | 0.0550 | 0.0800 | 0.0753 | 0.7145 | 0.7276 | 0.0000 | 0.0000 | 0.0039 | 0.0022 | 0.0039 | 0.0036 | 0.0123 | 0.0129 | 0.0578 | 0.0646 | 0.0884 | 0.0940 | 0.0676 | 0.0560 | 0.0799 | 0.0933 | 0.6862 | 0.6734 | 0.0006 | 0.0029 | 0.0053 | 0.0117 | 0.0516 | 0.0844 | 0.0668 | 0.0850 | 0.6917 | ||
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 264 | | 5714 | 20546 | 463.9 | 85.65 | 198.91 | 273.07 | 350 | 385 | 413 | 441 | 466 | 489 | 515 | 542 | 578 | 0.0555 | 1140 | 1.175 | 43.60 | 17.69 | 1 | 0.0201 | 115 | 0.0019 | 18.72 | 6.494 | 0.2565 | 222566.0 | 110000000 | 55900000000 | 29000000000000 | 0.4221 | 0.2293 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0015 | 0.0000 | 0.0127 | 0.0002 | 0.0579 | 0.0130 | 0.1134 | 0.0244 | 0.1170 | 0.0200 | 0.1731 | 0.0342 | 0.5233 | 0.9083 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0012 | 0.0000 | 0.0052 | 0.0002 | 0.0208 | 0.0122 | 0.0470 | 0.0219 | 0.0414 | 0.0133 | 0.0718 | 0.0193 | 0.8118 | 0.9331 | 0.0079 | 0.1000 | 0.0068 | 0.2500 | 0.0294 | 0.0750 | 0.0791 | 0.2000 | 0.1672 | 0.2250 | 0.2045 | 0.1000 | 0.1593 | 0.0500 | 0.1390 | 0.0000 | 0.2068 | 0.0000 | 0.0010 | 0.0021 | 0.0058 | 0.0158 | 0.0586 | 0.1059 | 0.0991 | 0.1464 | 0.5653 | 11 | 13 | 16 | 27 | 66 | 139 | 232 | 357 | 585 | 0.0741 | 43.15 | 5.361 | 0.5048 | 114131.0 | 92700000 | 90900000000 | 100000000000000 | 0.4547 | 0.1787 | 0.0206 | 0.0015 | 0.0989 | 0.0062 | 0.1742 | 0.0387 | 0.1784 | 0.0968 | 0.1954 | 0.1780 | 0.1632 | 0.1878 | 0.0692 | 0.1270 | 0.0643 | 0.1385 | 0.0358 | 0.2256 | 0.0000 | 0.0002 | 0.0004 | 0.0001 | 0.0016 | 0.0013 | 0.0107 | 0.0056 | 0.0397 | 0.0367 | 0.0708 | 0.0642 | 0.0517 | 0.0460 | 0.0770 | 0.0672 | 0.7482 | 0.7786 | 0.0000 | 0.0006 | 0.0017 | 0.0009 | 0.0036 | 0.0038 | 0.0119 | 0.0147 | 0.0501 | 0.0553 | 0.0831 | 0.0909 | 0.0729 | 0.0815 | 0.0904 | 0.0975 | 0.6863 | 0.6548 | 0.0004 | 0.0006 | 0.0018 | 0.0106 | 0.0445 | 0.0816 | 0.0606 | 0.0805 | 0.7194 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 550 | 347 | | 2625 | 7570 | 364.6 | 100.61 | 57.27 | 93.59 | 229 | 271 | 313 | 338 | 359 | 381 | 405 | 462 | 513 | 0.0856 | 648 | 0.595 | 111.40 | 19.31 | 7 | 0.1051 | 276 | 0.0012 | 33.64 | 6.958 | 0.2138 | 143052.0 | 59700000 | 26200000000 | 12000000000000 | 0.3697 | 0.2506 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0023 | 0.0162 | 0.0079 | 0.0855 | 0.0410 | 0.1179 | 0.0843 | 0.0929 | 0.0531 | 0.0899 | 0.0754 | 0.5969 | 0.7346 | 0.0000 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0035 | 0.0016 | 0.0333 | 0.0276 | 0.0455 | 0.0470 | 0.0414 | 0.0272 | 0.0510 | 0.0404 | 0.8253 | 0.8549 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0000 | 0.0216 | 0.0225 | 0.0396 | 0.0722 | 0.1367 | 0.1075 | 0.2086 | 0.0690 | 0.1223 | 0.1043 | 0.1295 | 0.6244 | 0.3309 | 0.0000 | 0.0008 | 0.0048 | 0.0191 | 0.0590 | 0.0901 | 0.0726 | 0.0989 | 0.6547 | 8 | 10 | 12 | 14 | 18 | 23 | 38 | 87 | 161 | 0.1461 | 5.86 | 3.394 | 0.7357 | 12038.0 | 4300000 | 1950000000 | 1010000000000 | 0.6794 | 0.0692 | 0.0238 | 0.0092 | 0.0506 | 0.0184 | 0.1131 | 0.0407 | 0.1310 | 0.0512 | 0.2292 | 0.1168 | 0.2083 | 0.1444 | 0.1280 | 0.1470 | 0.0893 | 0.1745 | 0.0268 | 0.2979 | 0.0019 | 0.0025 | 0.0014 | 0.0038 | 0.0068 | 0.0059 | 0.0106 | 0.0106 | 0.0323 | 0.0317 | 0.0651 | 0.0571 | 0.0458 | 0.0440 | 0.0719 | 0.0693 | 0.7641 | 0.7751 | 0.0006 | 0.0000 | 0.0012 | 0.0006 | 0.0035 | 0.0075 | 0.0098 | 0.0106 | 0.0368 | 0.0399 | 0.0725 | 0.0761 | 0.0478 | 0.0586 | 0.0725 | 0.0773 | 0.7553 | 0.7294 | 0.0005 | 0.0011 | 0.0053 | 0.0090 | 0.0329 | 0.0638 | 0.0515 | 0.0733 | 0.7625 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1240 | 782 | | 5520 | 5479 | 133.2 | 23.75 | 110.66 | 100.88 | 104 | 113 | 119 | 126 | 132 | 138 | 144 | 152 | 163 | 0.1374 | 753 | 0.999 | 91.29 | 24.70 | 1 | 0.0397 | 219 | 0.0031 | 14.38 | 6.066 | 0.2851 | 18294.8 | 2590000 | 379000000 | 57200000000 | 0.4125 | 0.2388 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0002 | 0.0212 | 0.0007 | 0.0442 | 0.0156 | 0.0934 | 0.0282 | 0.1204 | 0.0252 | 0.1646 | 0.0404 | 0.5507 | 0.8897 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0012 | 0.0000 | 0.0083 | 0.0002 | 0.0228 | 0.0129 | 0.0452 | 0.0203 | 0.0504 | 0.0132 | 0.0765 | 0.0234 | 0.7949 | 0.9300 | 0.0226 | 0.0169 | 0.0155 | 0.0763 | 0.0523 | 0.1102 | 0.1088 | 0.1102 | 0.1638 | 0.1525 | 0.1723 | 0.2034 | 0.1201 | 0.1356 | 0.1554 | 0.0847 | 0.1893 | 0.1102 | 0.0033 | 0.0089 | 0.0118 | 0.0380 | 0.0687 | 0.1048 | 0.1063 | 0.1384 | 0.5197 | 27 | 36 | 47 | 60 | 75 | 95 | 123 | 168 | 249 | 0.0062 | 29.53 | 5.971 | 0.3642 | 22419.6 | 6640000 | 2430000000 | 1010000000000 | 0.6287 | 0.0903 | 0.0259 | 0.0043 | 0.1147 | 0.0103 | 0.2160 | 0.0511 | 0.1732 | 0.0983 | 0.1395 | 0.1836 | 0.1192 | 0.1825 | 0.0934 | 0.1477 | 0.0742 | 0.1266 | 0.0439 | 0.1955 | 0.0017 | 0.0020 | 0.0034 | 0.0039 | 0.0089 | 0.0098 | 0.0326 | 0.0219 | 0.0852 | 0.0732 | 0.1360 | 0.1023 | 0.1004 | 0.0859 | 0.1513 | 0.1366 | 0.4805 | 0.5644 | 0.0020 | 0.0025 | 0.0095 | 0.0033 | 0.0102 | 0.0172 | 0.0428 | 0.0582 | 0.1292 | 0.1534 | 0.1747 | 0.1838 | 0.1237 | 0.1017 | 0.1475 | 0.1403 | 0.3603 | 0.3396 | 0.0016 | 0.0064 | 0.0155 | 0.0321 | 0.1095 | 0.1474 | 0.1239 | 0.1394 | 0.4241 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 584 | 956 | | 603 | 2463 | 406.2 | 49.35 | 106.45 | 171.74 | 341 | 360 | 374 | 391 | 405 | 421 | 434 | 449 | 475 | 0.1397 | 344 | 0.741 | 102.83 | 29.41 | 1 | 0.4809 | 290 | 0.0035 | 18.91 | 5.793 | 0.2498 | 167409.0 | 70000000 | 29700000000 | 12800000000000 | 0.3625 | 0.2807 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0037 | 0.0017 | 0.0608 | 0.0415 | 0.0958 | 0.0630 | 0.0608 | 0.0315 | 0.1105 | 0.0481 | 0.6648 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0034 | 0.0017 | 0.0444 | 0.0415 | 0.0650 | 0.0630 | 0.0342 | 0.0315 | 0.0581 | 0.0481 | 0.7932 | 0.8143 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0952 | 0.0000 | 0.1190 | 0.0000 | 0.1905 | 0.0000 | 0.2381 | 0.0000 | 0.1429 | 0.0000 | 0.1190 | 0.0000 | 0.0952 | 0.0000 | 0.0000 | 0.0000 | 0.0101 | 0.0269 | 0.0842 | 0.1010 | 0.1010 | 0.1279 | 0.5488 | 8 | 10 | 11 | 13 | 15 | 30 | 107 | 188 | 310 | 0.1805 | 23.87 | 3.814 | 0.6487 | 40814.5 | 22400000 | 14400000000 | 10100000000000 | 0.5211 | 0.1245 | 0.0866 | 0.0122 | 0.0551 | 0.0528 | 0.1417 | 0.1098 | 0.2205 | 0.1138 | 0.1575 | 0.1301 | 0.1890 | 0.1707 | 0.0787 | 0.1220 | 0.0236 | 0.1260 | 0.0472 | 0.1626 | 0.0012 | 0.0000 | 0.0000 | 0.0047 | 0.0025 | 0.0070 | 0.0149 | 0.0117 | 0.0532 | 0.0493 | 0.0916 | 0.0880 | 0.0668 | 0.0563 | 0.0693 | 0.0599 | 0.7005 | 0.7230 | 0.0015 | 0.0017 | 0.0000 | 0.0033 | 0.0132 | 0.0132 | 0.0264 | 0.0281 | 0.0543 | 0.0677 | 0.1189 | 0.1254 | 0.0764 | 0.0858 | 0.0837 | 0.1073 | 0.6256 | 0.5677 | 0.0000 | 0.0013 | 0.0040 | 0.0148 | 0.0617 | 0.1074 | 0.0671 | 0.0832 | 0.6604 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 701 | 856 | | 7996 | 17307 | 193.6 | 58.72 | 164.59 | 174.51 | 125 | 142 | 158 | 171 | 186 | 201 | 219 | 242 | 276 | 0.0699 | 1209 | 0.390 | 189.19 | 52.01 | 6 | 0.0969 | 775 | 0.0004 | 115.49 | 7.998 | 0.1188 | 40941.8 | 9380000 | 2310000000 | 607000000000 | 0.4229 | 0.2241 | 0.0005 | 0.0000 | 0.0018 | 0.0002 | 0.0094 | 0.0009 | 0.0411 | 0.0074 | 0.1168 | 0.0344 | 0.1900 | 0.0791 | 0.1790 | 0.0803 | 0.1954 | 0.1104 | 0.2659 | 0.6873 | 0.0003 | 0.0000 | 0.0010 | 0.0001 | 0.0019 | 0.0003 | 0.0127 | 0.0035 | 0.0368 | 0.0179 | 0.0736 | 0.0397 | 0.0694 | 0.0336 | 0.0989 | 0.0501 | 0.7053 | 0.8549 | 0.0011 | 0.0022 | 0.0058 | 0.0101 | 0.0132 | 0.0348 | 0.0529 | 0.0886 | 0.1242 | 0.1502 | 0.1564 | 0.1973 | 0.1036 | 0.1424 | 0.1416 | 0.1323 | 0.4012 | 0.2422 | 0.0011 | 0.0014 | 0.0067 | 0.0338 | 0.0799 | 0.1053 | 0.1028 | 0.1274 | 0.5416 | 12 | 17 | 27 | 57 | 103 | 156 | 220 | 301 | 416 | 0.0341 | 36.46 | 5.746 | 0.4218 | 57539.3 | 27000000 | 15300000000 | 10100000000000 | 0.6571 | 0.0586 | 0.0542 | 0.0031 | 0.1783 | 0.0167 | 0.2744 | 0.0940 | 0.1826 | 0.1421 | 0.1310 | 0.1851 | 0.0908 | 0.1972 | 0.0521 | 0.1171 | 0.0258 | 0.1158 | 0.0107 | 0.1290 | 0.0001 | 0.0001 | 0.0009 | 0.0003 | 0.0035 | 0.0017 | 0.0141 | 0.0100 | 0.0637 | 0.0508 | 0.1127 | 0.0947 | 0.0879 | 0.0669 | 0.1267 | 0.1070 | 0.5903 | 0.6684 | 0.0002 | 0.0012 | 0.0024 | 0.0030 | 0.0050 | 0.0089 | 0.0260 | 0.0344 | 0.0869 | 0.1000 | 0.1472 | 0.1606 | 0.1046 | 0.1172 | 0.1475 | 0.1538 | 0.4802 | 0.4209 | 0.0006 | 0.0016 | 0.0037 | 0.0192 | 0.0754 | 0.1313 | 0.0961 | 0.1295 | 0.5426 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 561 | 247 | | 4445 | 15033 | 466.1 | 65.09 | 63.62 | 138.06 | 379 | 413 | 433 | 450 | 466 | 481 | 499 | 521 | 551 | 0.0559 | 840 | 1.186 | 46.40 | 17.49 | 1 | 0.0270 | 120 | 0.0015 | 34.76 | 6.820 | 0.2169 | 221513.0 | 107000000 | 52800000000 | 26400000000000 | 0.4116 | 0.2311 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0035 | 0.0002 | 0.0355 | 0.0137 | 0.0646 | 0.0248 | 0.0635 | 0.0142 | 0.0910 | 0.0205 | 0.7407 | 0.9266 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0002 | 0.0221 | 0.0137 | 0.0368 | 0.0248 | 0.0314 | 0.0142 | 0.0456 | 0.0187 | 0.8620 | 0.9284 | 0.0110 | 1.0000 | 0.0192 | 0.0000 | 0.0219 | 0.0000 | 0.0959 | 0.0000 | 0.1479 | 0.0000 | 0.1726 | 0.0000 | 0.1397 | 0.0000 | 0.1288 | 0.0000 | 0.2630 | 0.0000 | 0.0004 | 0.0036 | 0.0085 | 0.0278 | 0.0732 | 0.0996 | 0.0961 | 0.1302 | 0.5606 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 57 | 200 | 0.2619 | 11.61 | 3.053 | 0.7574 | 23105.5 | 14100000 | 11000000000 | 10100000000000 | 0.4691 | 0.1844 | 0.0363 | 0.0081 | 0.0726 | 0.0208 | 0.0726 | 0.0728 | 0.1501 | 0.0786 | 0.1622 | 0.1110 | 0.1671 | 0.1260 | 0.1574 | 0.1191 | 0.1090 | 0.1445 | 0.0726 | 0.3191 | 0.0003 | 0.0012 | 0.0013 | 0.0030 | 0.0023 | 0.0044 | 0.0077 | 0.0094 | 0.0229 | 0.0195 | 0.0265 | 0.0301 | 0.0245 | 0.0248 | 0.0368 | 0.0387 | 0.8777 | 0.8689 | 0.0011 | 0.0000 | 0.0011 | 0.0004 | 0.0022 | 0.0024 | 0.0108 | 0.0091 | 0.0238 | 0.0234 | 0.0309 | 0.0313 | 0.0313 | 0.0317 | 0.0395 | 0.0527 | 0.8593 | 0.8490 | 0.0003 | 0.0007 | 0.0048 | 0.0104 | 0.0214 | 0.0308 | 0.0235 | 0.0443 | 0.8637 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 736 | 857 | | 16963 | 12738 | 140.2 | 47.70 | 284.47 | 272.42 | 86 | 103 | 115 | 125 | 135 | 146 | 159 | 175 | 199 | 0.1170 | 1490 | 0.454 | 104.36 | 26.02 | 3 | 0.0222 | 376 | 0.0013 | 28.58 | 7.013 | 0.2392 | 21921.8 | 3810000 | 736000000 | 159000000000 | 0.5138 | 0.1429 | 0.0011 | 0.0001 | 0.0046 | 0.0004 | 0.0190 | 0.0015 | 0.0417 | 0.0061 | 0.1096 | 0.0343 | 0.1753 | 0.0705 | 0.1648 | 0.0732 | 0.1725 | 0.1036 | 0.3113 | 0.7103 | 0.0003 | 0.0000 | 0.0016 | 0.0003 | 0.0030 | 0.0006 | 0.0086 | 0.0019 | 0.0379 | 0.0187 | 0.0685 | 0.0336 | 0.0683 | 0.0292 | 0.0917 | 0.0481 | 0.7201 | 0.8674 | 0.0029 | 0.0048 | 0.0072 | 0.0161 | 0.0144 | 0.0353 | 0.0503 | 0.0744 | 0.1120 | 0.1435 | 0.1511 | 0.1879 | 0.1142 | 0.0969 | 0.1336 | 0.1381 | 0.4144 | 0.3030 | 0.0010 | 0.0034 | 0.0085 | 0.0267 | 0.0777 | 0.1103 | 0.0988 | 0.1250 | 0.5485 | 17 | 30 | 70 | 134 | 213 | 299 | 394 | 506 | 659 | 0.0090 | 99.68 | 6.927 | 0.2797 | 155129.0 | 112000000 | 97700000000 | 101000000000000 | 0.5569 | 0.1416 | 0.0517 | 0.0052 | 0.1626 | 0.0189 | 0.2432 | 0.1060 | 0.1736 | 0.1157 | 0.1416 | 0.1826 | 0.1121 | 0.2064 | 0.0622 | 0.1365 | 0.0296 | 0.1148 | 0.0234 | 0.1139 | 0.0003 | 0.0000 | 0.0024 | 0.0010 | 0.0037 | 0.0030 | 0.0161 | 0.0098 | 0.0690 | 0.0611 | 0.1238 | 0.1119 | 0.0809 | 0.0760 | 0.1129 | 0.1040 | 0.5907 | 0.6331 | 0.0007 | 0.0011 | 0.0042 | 0.0032 | 0.0077 | 0.0122 | 0.0247 | 0.0416 | 0.0967 | 0.1108 | 0.1543 | 0.1728 | 0.1062 | 0.1147 | 0.1406 | 0.1433 | 0.4650 | 0.4004 | 0.0008 | 0.0013 | 0.0077 | 0.0199 | 0.0782 | 0.1419 | 0.0914 | 0.1252 | 0.5336 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1093 | 541 | | 6510 | 19083 | 329.3 | 67.71 | 96.25 | 108.79 | 246 | 270 | 288 | 306 | 322 | 340 | 362 | 390 | 424 | 0.0512 | 978 | 1.154 | 97.62 | 37.11 | 1 | 0.0393 | 256 | 0.0013 | 28.44 | 6.892 | 0.2102 | 112993.0 | 40300000 | 14900000000 | 5720000000000 | 0.4415 | 0.2097 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0043 | 0.0003 | 0.0149 | 0.0014 | 0.0652 | 0.0158 | 0.1269 | 0.0341 | 0.1409 | 0.0340 | 0.1777 | 0.0597 | 0.4684 | 0.8547 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0018 | 0.0000 | 0.0065 | 0.0002 | 0.0277 | 0.0116 | 0.0554 | 0.0212 | 0.0606 | 0.0158 | 0.0862 | 0.0306 | 0.7611 | 0.9207 | 0.0042 | 0.0157 | 0.0067 | 0.0000 | 0.0177 | 0.0627 | 0.0725 | 0.1412 | 0.1197 | 0.1961 | 0.1594 | 0.1843 | 0.1197 | 0.1451 | 0.1476 | 0.1451 | 0.3524 | 0.1098 | 0.0013 | 0.0033 | 0.0086 | 0.0309 | 0.0800 | 0.1165 | 0.1009 | 0.1201 | 0.5385 | 7 | 9 | 12 | 27 | 55 | 86 | 127 | 179 | 256 | 0.0642 | 12.35 | 5.075 | 0.5282 | 21099.1 | 6350000 | 2360000000 | 1030000000000 | 0.4788 | 0.1572 | 0.0140 | 0.0020 | 0.0726 | 0.0070 | 0.1767 | 0.0276 | 0.1707 | 0.0700 | 0.1712 | 0.1521 | 0.1612 | 0.1785 | 0.0996 | 0.1459 | 0.0776 | 0.1537 | 0.0566 | 0.2631 | 0.0004 | 0.0001 | 0.0007 | 0.0005 | 0.0036 | 0.0013 | 0.0080 | 0.0073 | 0.0353 | 0.0283 | 0.0641 | 0.0499 | 0.0529 | 0.0434 | 0.0741 | 0.0687 | 0.7611 | 0.8004 | 0.0005 | 0.0002 | 0.0015 | 0.0007 | 0.0028 | 0.0046 | 0.0118 | 0.0137 | 0.0486 | 0.0587 | 0.0819 | 0.0869 | 0.0679 | 0.0845 | 0.1039 | 0.1128 | 0.6810 | 0.6378 | 0.0004 | 0.0006 | 0.0017 | 0.0103 | 0.0404 | 0.0685 | 0.0604 | 0.0855 | 0.7323 | ||
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1182 | 506 | | 5215 | 17071 | 251.9 | 54.05 | 103.06 | 163.53 | 180 | 201 | 217 | 233 | 250 | 266 | 282 | 302 | 327 | 0.0592 | 1011 | 1.075 | 113.14 | 33.02 | 1 | 0.0516 | 269 | 0.0008 | 48.54 | 7.272 | 0.1797 | 66392.4 | 18200000 | 5190000000 | 1520000000000 | 0.4330 | 0.2117 | 0.0006 | 0.0000 | 0.0022 | 0.0000 | 0.0048 | 0.0000 | 0.0275 | 0.0022 | 0.0797 | 0.0138 | 0.1232 | 0.0367 | 0.1331 | 0.0359 | 0.1574 | 0.0648 | 0.4715 | 0.8468 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0010 | 0.0000 | 0.0077 | 0.0012 | 0.0289 | 0.0106 | 0.0534 | 0.0245 | 0.0530 | 0.0168 | 0.0732 | 0.0315 | 0.7817 | 0.9154 | 0.0029 | 0.0373 | 0.0097 | 0.0683 | 0.0165 | 0.0683 | 0.0584 | 0.1739 | 0.1051 | 0.2050 | 0.1907 | 0.1801 | 0.1430 | 0.1180 | 0.1459 | 0.0745 | 0.3278 | 0.0745 | 0.0004 | 0.0027 | 0.0059 | 0.0212 | 0.0550 | 0.1037 | 0.0923 | 0.1127 | 0.6060 | 8 | 10 | 12 | 14 | 19 | 40 | 88 | 178 | 323 | 0.1315 | 17.54 | 4.370 | 0.5904 | 37361.8 | 20200000 | 13400000000 | 10300000000000 | 0.5718 | 0.1052 | 0.0904 | 0.0025 | 0.2461 | 0.0286 | 0.3176 | 0.1880 | 0.1451 | 0.1835 | 0.0925 | 0.1830 | 0.0641 | 0.1810 | 0.0273 | 0.0847 | 0.0137 | 0.0762 | 0.0032 | 0.0727 | 0.0004 | 0.0000 | 0.0008 | 0.0005 | 0.0013 | 0.0015 | 0.0144 | 0.0131 | 0.0649 | 0.0555 | 0.1011 | 0.0975 | 0.0663 | 0.0604 | 0.0930 | 0.0903 | 0.6578 | 0.6812 | 0.0005 | 0.0005 | 0.0016 | 0.0020 | 0.0060 | 0.0048 | 0.0196 | 0.0218 | 0.0670 | 0.0698 | 0.1097 | 0.1043 | 0.0649 | 0.0698 | 0.0947 | 0.0959 | 0.6360 | 0.6311 | 0.0004 | 0.0010 | 0.0042 | 0.0151 | 0.0692 | 0.1025 | 0.0681 | 0.0903 | 0.6491 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1239 | 302 | | 2914 | 11468 | 89.0 | 23.47 | 185.84 | 181.95 | 62 | 70 | 76 | 82 | 86 | 92 | 98 | 105 | 117 | 0.0557 | 639 | 1.081 | 95.21 | 32.02 | 1 | 0.0824 | 240 | 0.0040 | 15.08 | 5.828 | 0.3126 | 8469.4 | 866721 | 96000000 | 11600000000 | 0.4610 | 0.1943 | 0.0023 | 0.0000 | 0.0046 | 0.0011 | 0.0200 | 0.0027 | 0.0372 | 0.0057 | 0.0910 | 0.0289 | 0.1390 | 0.0427 | 0.1653 | 0.0632 | 0.2105 | 0.0967 | 0.3301 | 0.7589 | 0.0009 | 0.0000 | 0.0013 | 0.0004 | 0.0071 | 0.0000 | 0.0106 | 0.0014 | 0.0468 | 0.0195 | 0.0693 | 0.0287 | 0.0803 | 0.0337 | 0.1112 | 0.0553 | 0.6727 | 0.8611 | 0.0173 | 0.0000 | 0.0135 | 0.0406 | 0.0308 | 0.0508 | 0.0963 | 0.1015 | 0.1638 | 0.1929 | 0.1503 | 0.1675 | 0.1233 | 0.1168 | 0.1561 | 0.1269 | 0.2486 | 0.2030 | 0.0007 | 0.0045 | 0.0164 | 0.0425 | 0.0970 | 0.1231 | 0.1351 | 0.1552 | 0.4254 | 18 | 23 | 38 | 72 | 122 | 186 | 260 | 345 | 454 | 0.0125 | 51.50 | 6.479 | 0.3282 | 67639.0 | 31600000 | 17100000000 | 10300000000000 | 0.5344 | 0.1560 | 0.0634 | 0.0020 | 0.2146 | 0.0083 | 0.2992 | 0.1102 | 0.1675 | 0.1972 | 0.0951 | 0.2102 | 0.0764 | 0.1783 | 0.0472 | 0.1063 | 0.0187 | 0.0960 | 0.0179 | 0.0917 | 0.0002 | 0.0000 | 0.0004 | 0.0007 | 0.0031 | 0.0017 | 0.0183 | 0.0137 | 0.0645 | 0.0576 | 0.1169 | 0.1040 | 0.0833 | 0.0705 | 0.1163 | 0.1042 | 0.5970 | 0.6476 | 0.0010 | 0.0015 | 0.0027 | 0.0029 | 0.0067 | 0.0102 | 0.0284 | 0.0344 | 0.0832 | 0.0857 | 0.1256 | 0.1409 | 0.0964 | 0.1038 | 0.1348 | 0.1269 | 0.5211 | 0.4937 | 0.0009 | 0.0022 | 0.0037 | 0.0224 | 0.0757 | 0.1246 | 0.0944 | 0.1173 | 0.5588 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 849 | 648 | | 5112 | 6565 | 125.8 | 31.35 | 178.35 | 174.51 | 89 | 99 | 108 | 116 | 122 | 129 | 138 | 149 | 167 | 0.1097 | 720 | 1.162 | 109.62 | 38.12 | 1 | 0.0534 | 273 | 0.0023 | 21.62 | 6.373 | 0.2588 | 16819.2 | 2390000 | 363000000 | 58800000000 | 0.4232 | 0.2346 | 0.0006 | 0.0000 | 0.0042 | 0.0000 | 0.0130 | 0.0002 | 0.0250 | 0.0036 | 0.0815 | 0.0212 | 0.1644 | 0.0559 | 0.1624 | 0.0520 | 0.1722 | 0.0780 | 0.3765 | 0.7890 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0012 | 0.0000 | 0.0055 | 0.0006 | 0.0352 | 0.0126 | 0.0852 | 0.0358 | 0.0745 | 0.0194 | 0.0985 | 0.0372 | 0.6986 | 0.8945 | 0.0022 | 0.0030 | 0.0087 | 0.0208 | 0.0282 | 0.0653 | 0.1062 | 0.1187 | 0.1593 | 0.1988 | 0.1907 | 0.1691 | 0.1192 | 0.1128 | 0.1148 | 0.0950 | 0.2709 | 0.2166 | 0.0022 | 0.0052 | 0.0108 | 0.0388 | 0.1086 | 0.1483 | 0.1198 | 0.1362 | 0.4302 | 16 | 28 | 49 | 82 | 120 | 170 | 233 | 311 | 426 | 0.0054 | 96.61 | 6.816 | 0.3013 | 62256.2 | 29200000 | 16400000000 | 10300000000000 | 0.4788 | 0.1616 | 0.0394 | 0.0012 | 0.1386 | 0.0088 | 0.2664 | 0.0649 | 0.1673 | 0.1257 | 0.1589 | 0.1784 | 0.1147 | 0.2041 | 0.0514 | 0.1509 | 0.0346 | 0.1222 | 0.0287 | 0.1439 | 0.0000 | 0.0003 | 0.0007 | 0.0000 | 0.0023 | 0.0011 | 0.0171 | 0.0077 | 0.0635 | 0.0541 | 0.1070 | 0.0913 | 0.0846 | 0.0677 | 0.1084 | 0.1006 | 0.6164 | 0.6772 | 0.0009 | 0.0000 | 0.0023 | 0.0028 | 0.0070 | 0.0083 | 0.0232 | 0.0319 | 0.0859 | 0.0979 | 0.1226 | 0.1364 | 0.0878 | 0.0974 | 0.1333 | 0.1320 | 0.5369 | 0.4934 | 0.0008 | 0.0008 | 0.0055 | 0.0169 | 0.0777 | 0.1131 | 0.0868 | 0.1190 | 0.5795 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 742 | 248 | | 1325 | 5484 | 955.8 | 428.77 | 8.01 | 2.97 | 481 | 526 | 610 | 705 | 833 | 1020 | 1224 | 1418 | 1627 | 0.0857 | 470 | 0.902 | 36.72 | 12.08 | 1 | 0.0823 | 109 | 0.0016 | 81.60 | 6.699 | 0.1744 | 1100000.0 | 1440000000 | 2060000000000 | 3.12E+15 | 0.3703 | 0.2538 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0110 | 0.0015 | 0.1801 | 0.0682 | 0.2904 | 0.1091 | 0.1360 | 0.0636 | 0.1324 | 0.1197 | 0.2500 | 0.6348 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0360 | 0.0308 | 0.0596 | 0.0473 | 0.0263 | 0.0226 | 0.0526 | 0.0473 | 0.8241 | 0.8520 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0022 | 0.0128 | 0.0511 | 0.0511 | 0.0644 | 0.0831 | 0.0378 | 0.0511 | 0.0578 | 0.0895 | 0.7867 | 0.7093 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0417 | 0.0609 | 0.0330 | 0.0557 | 0.8070 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 12 | 0.0134 | 9.32 | 4.700 | 0.3378 | 73.0 | 745.296 | 8414.3 | 103808 | 0.4557 | 0.1834 | 0.0246 | 0.0007 | 0.0780 | 0.0051 | 0.1560 | 0.0156 | 0.2275 | 0.0356 | 0.2236 | 0.0749 | 0.1629 | 0.1318 | 0.0948 | 0.2083 | 0.0289 | 0.2962 | 0.0039 | 0.2318 | 0.0045 | 0.0000 | 0.0206 | 0.0000 | 0.0448 | 0.0044 | 0.0775 | 0.0143 | 0.1104 | 0.0457 | 0.1205 | 0.0733 | 0.1415 | 0.1199 | 0.1700 | 0.2262 | 0.3102 | 0.5161 | 0.0910 | 0.1312 | 0.0842 | 0.1131 | 0.0910 | 0.1508 | 0.1045 | 0.1146 | 0.1270 | 0.1071 | 0.1222 | 0.1056 | 0.1283 | 0.1071 | 0.1236 | 0.0920 | 0.1283 | 0.0784 | 0.0246 | 0.0667 | 0.0896 | 0.1051 | 0.0958 | 0.1127 | 0.1221 | 0.1629 | 0.2206 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 750 | 676 | | 11146 | 21855 | 106.6 | 28.30 | 189.51 | 171.91 | 74 | 83 | 90 | 97 | 103 | 110 | 118 | 128 | 143 | 0.0573 | 1252 | 0.886 | 106.10 | 29.53 | 1 | 0.0241 | 269 | 0.0014 | 32.07 | 6.896 | 0.2173 | 12166.0 | 1490000 | 200000000 | 29600000000 | 0.4458 | 0.2114 | 0.0009 | 0.0000 | 0.0026 | 0.0003 | 0.0096 | 0.0013 | 0.0300 | 0.0038 | 0.0861 | 0.0213 | 0.1508 | 0.0508 | 0.1608 | 0.0587 | 0.1819 | 0.0839 | 0.3773 | 0.7799 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0039 | 0.0003 | 0.0101 | 0.0021 | 0.0393 | 0.0133 | 0.0634 | 0.0258 | 0.0685 | 0.0231 | 0.0980 | 0.0366 | 0.7155 | 0.8988 | 0.0018 | 0.0088 | 0.0088 | 0.0164 | 0.0226 | 0.0582 | 0.0647 | 0.1239 | 0.1317 | 0.2010 | 0.1714 | 0.1795 | 0.1183 | 0.1163 | 0.1423 | 0.1277 | 0.3383 | 0.1681 | 0.0014 | 0.0032 | 0.0116 | 0.0332 | 0.0812 | 0.1162 | 0.1018 | 0.1287 | 0.5226 | 16 | 35 | 67 | 103 | 142 | 190 | 249 | 320 | 433 | 0.0120 | 37.39 | 6.296 | 0.3650 | 65463.6 | 30100000 | 16600000000 | 10400000000000 | 0.5497 | 0.1277 | 0.0358 | 0.0017 | 0.1299 | 0.0109 | 0.2197 | 0.0768 | 0.1613 | 0.1097 | 0.1616 | 0.1610 | 0.1328 | 0.1855 | 0.0738 | 0.1385 | 0.0543 | 0.1308 | 0.0308 | 0.1851 | 0.0000 | 0.0000 | 0.0012 | 0.0012 | 0.0025 | 0.0022 | 0.0135 | 0.0090 | 0.0598 | 0.0462 | 0.1069 | 0.0836 | 0.0781 | 0.0656 | 0.1195 | 0.1003 | 0.6185 | 0.6919 | 0.0006 | 0.0002 | 0.0018 | 0.0023 | 0.0045 | 0.0088 | 0.0267 | 0.0326 | 0.0915 | 0.1031 | 0.1477 | 0.1742 | 0.1100 | 0.1208 | 0.1446 | 0.1560 | 0.4726 | 0.4020 | 0.0002 | 0.0008 | 0.0031 | 0.0184 | 0.0746 | 0.1276 | 0.0976 | 0.1359 | 0.5419 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1215 | 337 | | 5299 | 15208 | 314.6 | 49.18 | 289.78 | 445.68 | 258 | 273 | 285 | 295 | 306 | 318 | 334 | 356 | 383 | 0.0592 | 900 | 0.916 | 116.83 | 42.76 | 1 | 0.0670 | 355 | 0.0017 | 23.16 | 6.655 | 0.2317 | 101403.0 | 33500000 | 11400000000 | 3950000000000 | 0.3986 | 0.2511 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0000 | 0.0093 | 0.0002 | 0.0305 | 0.0140 | 0.0753 | 0.0305 | 0.0827 | 0.0190 | 0.1286 | 0.0295 | 0.6705 | 0.9068 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0000 | 0.0158 | 0.0117 | 0.0404 | 0.0247 | 0.0404 | 0.0102 | 0.0640 | 0.0160 | 0.8348 | 0.9373 | 0.0063 | 0.0000 | 0.0158 | 0.0000 | 0.0412 | 0.0000 | 0.0824 | 0.0000 | 0.1173 | 0.0000 | 0.1347 | 0.0000 | 0.1094 | 0.0000 | 0.1410 | 0.0000 | 0.3518 | 0.0000 | 0.0022 | 0.0083 | 0.0188 | 0.0419 | 0.0777 | 0.1104 | 0.0877 | 0.1144 | 0.5386 | 14 | 17 | 20 | 24 | 37 | 96 | 310 | 568 | 955 | 0.0512 | 92.27 | 5.412 | 0.4889 | 282587.0 | 374000000 | 589000000000 | 1.04E+15 | 0.4260 | 0.2078 | 0.0678 | 0.0021 | 0.2554 | 0.0310 | 0.2713 | 0.1590 | 0.1515 | 0.1654 | 0.1154 | 0.1977 | 0.0736 | 0.1668 | 0.0375 | 0.0880 | 0.0202 | 0.0992 | 0.0072 | 0.0908 | 0.0000 | 0.0000 | 0.0002 | 0.0006 | 0.0006 | 0.0002 | 0.0058 | 0.0039 | 0.0392 | 0.0362 | 0.0676 | 0.0614 | 0.0464 | 0.0369 | 0.0642 | 0.0614 | 0.7760 | 0.7994 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0016 | 0.0038 | 0.0107 | 0.0111 | 0.0513 | 0.0494 | 0.0801 | 0.0970 | 0.0632 | 0.0688 | 0.0880 | 0.0932 | 0.7051 | 0.6762 | 0.0000 | 0.0000 | 0.0009 | 0.0068 | 0.0458 | 0.0717 | 0.0503 | 0.0824 | 0.7421 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1074 | 767 | | 4851 | 8558 | 206.5 | 55.00 | 108.27 | 109.37 | 139 | 160 | 174 | 187 | 202 | 217 | 232 | 251 | 282 | 0.1187 | 1016 | 0.484 | 105.59 | 20.81 | 4 | 0.0662 | 321 | 0.0008 | 57.36 | 7.309 | 0.1587 | 45680.7 | 10800000 | 2680000000 | 703000000000 | 0.4637 | 0.1868 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0086 | 0.0009 | 0.0413 | 0.0069 | 0.0994 | 0.0313 | 0.1640 | 0.0778 | 0.1659 | 0.0680 | 0.1872 | 0.1041 | 0.3321 | 0.7110 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0019 | 0.0006 | 0.0119 | 0.0039 | 0.0380 | 0.0199 | 0.0697 | 0.0448 | 0.0629 | 0.0307 | 0.0941 | 0.0474 | 0.7209 | 0.8527 | 0.0078 | 0.0123 | 0.0059 | 0.0123 | 0.0157 | 0.0567 | 0.0793 | 0.0961 | 0.1360 | 0.1995 | 0.1634 | 0.1847 | 0.1164 | 0.1059 | 0.1585 | 0.1256 | 0.3170 | 0.2069 | 0.0000 | 0.0013 | 0.0048 | 0.0255 | 0.0867 | 0.1175 | 0.1122 | 0.1373 | 0.5147 | 12 | 18 | 29 | 47 | 69 | 99 | 134 | 187 | 268 | 0.0244 | 13.32 | 5.257 | 0.4878 | 23683.4 | 7140000 | 2580000000 | 1050000000000 | 0.5580 | 0.1201 | 0.0405 | 0.0014 | 0.1364 | 0.0151 | 0.1957 | 0.0713 | 0.2286 | 0.1138 | 0.1722 | 0.1731 | 0.1091 | 0.2097 | 0.0640 | 0.1398 | 0.0301 | 0.1316 | 0.0235 | 0.1444 | 0.0008 | 0.0007 | 0.0029 | 0.0009 | 0.0080 | 0.0059 | 0.0252 | 0.0204 | 0.0707 | 0.0557 | 0.1162 | 0.1042 | 0.0849 | 0.0847 | 0.1154 | 0.1074 | 0.5760 | 0.6202 | 0.0007 | 0.0027 | 0.0045 | 0.0063 | 0.0142 | 0.0144 | 0.0359 | 0.0395 | 0.0864 | 0.0997 | 0.1253 | 0.1307 | 0.1029 | 0.1150 | 0.1377 | 0.1370 | 0.4923 | 0.4546 | 0.0019 | 0.0031 | 0.0084 | 0.0273 | 0.0769 | 0.1256 | 0.0924 | 0.1293 | 0.5352 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 912 | 233 | | 5870 | 24688 | 277.0 | 63.32 | 98.44 | 168.31 | 201 | 221 | 239 | 254 | 270 | 286 | 305 | 329 | 365 | 0.0475 | 1173 | 1.191 | 103.82 | 38.01 | 1 | 0.0428 | 251 | 0.0007 | 63.63 | 7.502 | 0.1601 | 80724.4 | 24700000 | 7930000000 | 2660000000000 | 0.4510 | 0.1942 | 0.0003 | 0.0002 | 0.0008 | 0.0000 | 0.0031 | 0.0002 | 0.0165 | 0.0020 | 0.0684 | 0.0184 | 0.1377 | 0.0460 | 0.1419 | 0.0408 | 0.1640 | 0.0561 | 0.4673 | 0.8362 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0009 | 0.0293 | 0.0110 | 0.0611 | 0.0250 | 0.0609 | 0.0155 | 0.0819 | 0.0242 | 0.7602 | 0.9234 | 0.0009 | 0.0028 | 0.0090 | 0.0056 | 0.0126 | 0.0306 | 0.0531 | 0.1142 | 0.1178 | 0.1783 | 0.1610 | 0.2256 | 0.1088 | 0.1226 | 0.1403 | 0.1448 | 0.3966 | 0.1755 | 0.0004 | 0.0041 | 0.0137 | 0.0375 | 0.0742 | 0.1187 | 0.0968 | 0.1246 | 0.5300 | 8 | 9 | 11 | 13 | 16 | 27 | 65 | 158 | 326 | 0.1748 | 15.56 | 4.062 | 0.6361 | 38015.9 | 21300000 | 14100000000 | 10500000000000 | 0.4506 | 0.1916 | 0.0704 | 0.0013 | 0.2291 | 0.0191 | 0.3221 | 0.1226 | 0.1709 | 0.2079 | 0.1033 | 0.2447 | 0.0648 | 0.1724 | 0.0207 | 0.1000 | 0.0122 | 0.0771 | 0.0066 | 0.0550 | 0.0003 | 0.0000 | 0.0009 | 0.0005 | 0.0010 | 0.0014 | 0.0081 | 0.0111 | 0.0458 | 0.0427 | 0.0835 | 0.0736 | 0.0487 | 0.0501 | 0.0777 | 0.0719 | 0.7339 | 0.7487 | 0.0002 | 0.0004 | 0.0005 | 0.0002 | 0.0019 | 0.0032 | 0.0112 | 0.0119 | 0.0561 | 0.0571 | 0.0878 | 0.0924 | 0.0591 | 0.0641 | 0.0930 | 0.0948 | 0.6903 | 0.6760 | 0.0002 | 0.0000 | 0.0017 | 0.0096 | 0.0502 | 0.0854 | 0.0527 | 0.0840 | 0.7161 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 948 | 93 | | 6191 | 5411 | 97.2 | 28.78 | 176.56 | 250.57 | 65 | 74 | 81 | 88 | 94 | 101 | 108 | 118 | 134 | 0.1785 | 966 | 0.915 | 160.59 | 50.92 | 3 | 0.0728 | 451 | 0.0012 | 44.43 | 7.019 | 0.1810 | 10281.0 | 1180000 | 147000000 | 20000000000 | 0.4296 | 0.2140 | 0.0006 | 0.0000 | 0.0021 | 0.0000 | 0.0200 | 0.0011 | 0.0445 | 0.0080 | 0.1179 | 0.0337 | 0.1765 | 0.0649 | 0.1815 | 0.0792 | 0.1824 | 0.1193 | 0.2744 | 0.6938 | 0.0004 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0003 | 0.0120 | 0.0043 | 0.0482 | 0.0193 | 0.0816 | 0.0358 | 0.0819 | 0.0379 | 0.1103 | 0.0573 | 0.6632 | 0.8451 | 0.0046 | 0.0144 | 0.0144 | 0.0341 | 0.0311 | 0.0485 | 0.0971 | 0.0987 | 0.1115 | 0.1813 | 0.1624 | 0.1418 | 0.1252 | 0.0987 | 0.1373 | 0.1275 | 0.3164 | 0.2549 | 0.0028 | 0.0059 | 0.0121 | 0.0385 | 0.0905 | 0.1273 | 0.1099 | 0.1328 | 0.4802 | 19 | 24 | 31 | 44 | 66 | 104 | 177 | 282 | 478 | 0.0405 | 26.68 | 4.951 | 0.5100 | 93949.7 | 80000000 | 85800000000 | 105000000000000 | 0.6057 | 0.0948 | 0.1074 | 0.0033 | 0.2729 | 0.0546 | 0.2550 | 0.2116 | 0.1208 | 0.1860 | 0.1230 | 0.1815 | 0.0582 | 0.1503 | 0.0425 | 0.0846 | 0.0201 | 0.0579 | 0.0000 | 0.0702 | 0.0005 | 0.0005 | 0.0043 | 0.0019 | 0.0086 | 0.0075 | 0.0311 | 0.0230 | 0.1063 | 0.0962 | 0.1283 | 0.1304 | 0.1063 | 0.0863 | 0.1546 | 0.1487 | 0.4600 | 0.5056 | 0.0007 | 0.0016 | 0.0071 | 0.0049 | 0.0127 | 0.0138 | 0.0438 | 0.0454 | 0.1243 | 0.1410 | 0.1653 | 0.1896 | 0.1165 | 0.1135 | 0.1645 | 0.1564 | 0.3651 | 0.3339 | 0.0018 | 0.0037 | 0.0098 | 0.0331 | 0.1227 | 0.1466 | 0.1110 | 0.1724 | 0.3988 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 994 | 366 | | 5578 | 9502 | 439.0 | 109.23 | 7.27 | 7.81 | 292 | 342 | 380 | 410 | 440 | 471 | 499 | 532 | 577 | 0.0764 | 726 | 0.939 | 87.10 | 28.18 | 1 | 0.0446 | 249 | 0.0007 | 54.37 | 7.463 | 0.1610 | 204683.0 | 101000000 | 51800000000 | 27900000000000 | 0.4190 | 0.2212 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0035 | 0.0004 | 0.0227 | 0.0026 | 0.0796 | 0.0200 | 0.1332 | 0.0381 | 0.1486 | 0.0495 | 0.1674 | 0.0707 | 0.4438 | 0.8187 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0004 | 0.0055 | 0.0021 | 0.0249 | 0.0145 | 0.0386 | 0.0203 | 0.0420 | 0.0202 | 0.0598 | 0.0259 | 0.8277 | 0.9167 | 0.0025 | 0.0150 | 0.0083 | 0.0300 | 0.0108 | 0.0936 | 0.0717 | 0.1685 | 0.1350 | 0.1648 | 0.1983 | 0.1985 | 0.1250 | 0.0749 | 0.1433 | 0.0599 | 0.3050 | 0.1948 | 0.0011 | 0.0014 | 0.0018 | 0.0164 | 0.0513 | 0.0969 | 0.0840 | 0.1033 | 0.6439 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.3430 | 0.51 | 1.198 | 0.7294 | 113.9 | 6884.51 | 785459 | 106000000 | 0.5832 | 0.1225 | 0.0192 | 0.0019 | 0.0770 | 0.0156 | 0.1579 | 0.0462 | 0.2263 | 0.1039 | 0.2280 | 0.1979 | 0.1695 | 0.2473 | 0.0885 | 0.2176 | 0.0290 | 0.1308 | 0.0047 | 0.0389 | 0.0061 | 0.0001 | 0.0245 | 0.0052 | 0.0678 | 0.0214 | 0.1121 | 0.0524 | 0.1595 | 0.1246 | 0.1671 | 0.1799 | 0.1649 | 0.2137 | 0.1572 | 0.2103 | 0.1408 | 0.1925 | 0.1745 | 0.1950 | 0.1707 | 0.1376 | 0.1329 | 0.1217 | 0.1097 | 0.1088 | 0.0929 | 0.0945 | 0.0843 | 0.0801 | 0.0659 | 0.0748 | 0.0751 | 0.0786 | 0.0940 | 0.1088 | 0.0231 | 0.0695 | 0.1299 | 0.1560 | 0.1619 | 0.1493 | 0.1157 | 0.0965 | 0.0981 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 620 | 230 | | 4285 | 3286 | 144.3 | 36.47 | 138.38 | 91.26 | 103 | 114 | 122 | 130 | 138 | 148 | 158 | 173 | 194 | 0.1869 | 614 | 1.042 | 86.49 | 33.29 | 1 | 0.0567 | 243 | 0.0019 | 26.80 | 6.577 | 0.2264 | 22156.9 | 3620000 | 632000000 | 117000000000 | 0.4068 | 0.2461 | 0.0008 | 0.0000 | 0.0024 | 0.0000 | 0.0068 | 0.0008 | 0.0409 | 0.0036 | 0.0895 | 0.0250 | 0.1604 | 0.0595 | 0.1805 | 0.0680 | 0.1781 | 0.0883 | 0.3406 | 0.7550 | 0.0003 | 0.0000 | 0.0015 | 0.0000 | 0.0033 | 0.0007 | 0.0152 | 0.0019 | 0.0396 | 0.0150 | 0.0677 | 0.0307 | 0.0793 | 0.0309 | 0.0999 | 0.0421 | 0.6933 | 0.8786 | 0.0023 | 0.0063 | 0.0058 | 0.0284 | 0.0232 | 0.0473 | 0.0719 | 0.1356 | 0.1241 | 0.1703 | 0.1694 | 0.2177 | 0.1230 | 0.1041 | 0.1381 | 0.1104 | 0.3422 | 0.1798 | 0.0011 | 0.0074 | 0.0079 | 0.0370 | 0.0894 | 0.1174 | 0.1259 | 0.1364 | 0.4775 | 49 | 67 | 82 | 100 | 117 | 136 | 159 | 195 | 252 | 0.0034 | 28.02 | 6.143 | 0.3124 | 27476.4 | 7420000 | 2560000000 | 1060000000000 | 0.5807 | 0.0980 | 0.0129 | 0.0006 | 0.0526 | 0.0104 | 0.1671 | 0.0245 | 0.1542 | 0.0736 | 0.1916 | 0.1373 | 0.1729 | 0.1674 | 0.1320 | 0.1582 | 0.0713 | 0.1398 | 0.0456 | 0.2882 | 0.0006 | 0.0000 | 0.0034 | 0.0030 | 0.0130 | 0.0039 | 0.0419 | 0.0226 | 0.1058 | 0.0826 | 0.1533 | 0.1274 | 0.1250 | 0.1044 | 0.1408 | 0.1261 | 0.4163 | 0.5298 | 0.0066 | 0.0075 | 0.0055 | 0.0105 | 0.0362 | 0.0359 | 0.0768 | 0.0734 | 0.1480 | 0.1722 | 0.1612 | 0.1722 | 0.1261 | 0.1257 | 0.1469 | 0.1437 | 0.2928 | 0.2590 | 0.0023 | 0.0046 | 0.0201 | 0.0610 | 0.1251 | 0.1807 | 0.1127 | 0.1490 | 0.3444 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 558 | 297 | | 5154 | 21541 | 500.5 | 100.92 | 62.27 | 98.68 | 379 | 413 | 441 | 465 | 489 | 516 | 545 | 583 | 643 | 0.0452 | 974 | 1.154 | 82.42 | 31.26 | 1 | 0.0415 | 214 | 0.0008 | 54.34 | 7.369 | 0.1710 | 260702.0 | 141000000 | 79400000000 | 46200000000000 | 0.4202 | 0.2271 | 0.0003 | 0.0000 | 0.0009 | 0.0000 | 0.0017 | 0.0002 | 0.0098 | 0.0012 | 0.0500 | 0.0161 | 0.1015 | 0.0368 | 0.0980 | 0.0279 | 0.1322 | 0.0328 | 0.6056 | 0.8850 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0006 | 0.0245 | 0.0117 | 0.0493 | 0.0242 | 0.0433 | 0.0125 | 0.0646 | 0.0189 | 0.8118 | 0.9320 | 0.0012 | 0.0000 | 0.0048 | 0.0048 | 0.0119 | 0.0193 | 0.0523 | 0.1063 | 0.1010 | 0.1401 | 0.1354 | 0.2415 | 0.0926 | 0.0918 | 0.1330 | 0.1594 | 0.4679 | 0.2367 | 0.0004 | 0.0034 | 0.0068 | 0.0256 | 0.0631 | 0.1062 | 0.0981 | 0.1207 | 0.5755 | 7 | 8 | 9 | 11 | 13 | 22 | 54 | 107 | 186 | 0.1524 | 8.90 | 3.882 | 0.6556 | 13615.0 | 4670000 | 2040000000 | 1060000000000 | 0.5472 | 0.1233 | 0.0212 | 0.0048 | 0.0778 | 0.0100 | 0.2184 | 0.0291 | 0.2431 | 0.0917 | 0.2007 | 0.1943 | 0.1344 | 0.2273 | 0.0654 | 0.1586 | 0.0309 | 0.1369 | 0.0080 | 0.1473 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0018 | 0.0020 | 0.0078 | 0.0083 | 0.0383 | 0.0319 | 0.0619 | 0.0584 | 0.0403 | 0.0398 | 0.0605 | 0.0521 | 0.7895 | 0.8065 | 0.0000 | 0.0004 | 0.0009 | 0.0014 | 0.0032 | 0.0038 | 0.0112 | 0.0113 | 0.0443 | 0.0457 | 0.0656 | 0.0707 | 0.0474 | 0.0532 | 0.0740 | 0.0811 | 0.7534 | 0.7324 | 0.0003 | 0.0000 | 0.0021 | 0.0080 | 0.0402 | 0.0651 | 0.0435 | 0.0623 | 0.7784 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 705 | 883 | | 6676 | 9244 | 499.2 | 67.15 | 152.67 | 174.40 | 413 | 445 | 465 | 483 | 499 | 516 | 533 | 554 | 585 | 0.0900 | 832 | 1.232 | 101.42 | 42.43 | 1 | 0.0400 | 267 | 0.0009 | 54.50 | 7.284 | 0.1641 | 253716.0 | 131000000 | 68900000000 | 36800000000000 | 0.4286 | 0.2213 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0060 | 0.0000 | 0.0214 | 0.0109 | 0.0488 | 0.0210 | 0.0590 | 0.0100 | 0.0846 | 0.0168 | 0.7780 | 0.9412 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0000 | 0.0136 | 0.0106 | 0.0283 | 0.0205 | 0.0247 | 0.0094 | 0.0369 | 0.0151 | 0.8931 | 0.9443 | 0.0165 | 0.0000 | 0.0412 | 0.0000 | 0.0576 | 0.0000 | 0.0864 | 0.0000 | 0.1358 | 0.0000 | 0.1296 | 0.0000 | 0.1276 | 0.0000 | 0.1379 | 0.0000 | 0.2675 | 0.0000 | 0.0018 | 0.0036 | 0.0083 | 0.0283 | 0.0676 | 0.1221 | 0.1140 | 0.1355 | 0.5189 | 19 | 26 | 37 | 53 | 74 | 110 | 169 | 273 | 415 | 0.0207 | 24.07 | 5.517 | 0.4810 | 53719.9 | 26700000 | 15900000000 | 10600000000000 | 0.4686 | 0.1593 | 0.0797 | 0.0005 | 0.2210 | 0.0235 | 0.2295 | 0.1208 | 0.1292 | 0.1504 | 0.1075 | 0.1711 | 0.0821 | 0.1602 | 0.0483 | 0.1022 | 0.0628 | 0.1203 | 0.0399 | 0.1509 | 0.0003 | 0.0002 | 0.0015 | 0.0005 | 0.0038 | 0.0027 | 0.0145 | 0.0131 | 0.0737 | 0.0515 | 0.1088 | 0.1038 | 0.0748 | 0.0620 | 0.1129 | 0.1048 | 0.6098 | 0.6614 | 0.0000 | 0.0000 | 0.0008 | 0.0035 | 0.0050 | 0.0039 | 0.0218 | 0.0226 | 0.0916 | 0.0960 | 0.1439 | 0.1633 | 0.0871 | 0.0886 | 0.1226 | 0.1363 | 0.5273 | 0.4859 | 0.0003 | 0.0003 | 0.0037 | 0.0141 | 0.0844 | 0.1335 | 0.0820 | 0.1187 | 0.5629 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 296 | 572 | | 8086 | 26684 | 302.2 | 79.97 | 205.86 | 280.95 | 205 | 239 | 262 | 283 | 304 | 326 | 349 | 373 | 401 | 0.0475 | 1267 | 0.665 | 59.68 | 11.31 | 3 | 0.0177 | 143 | 0.0008 | 40.70 | 7.343 | 0.1978 | 97719.6 | 33200000 | 11800000000 | 4310000000000 | 0.3795 | 0.2472 | 0.0011 | 0.0000 | 0.0016 | 0.0000 | 0.0074 | 0.0003 | 0.0207 | 0.0023 | 0.0767 | 0.0172 | 0.1294 | 0.0437 | 0.1280 | 0.0397 | 0.1701 | 0.0578 | 0.4650 | 0.8391 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0016 | 0.0000 | 0.0058 | 0.0012 | 0.0212 | 0.0116 | 0.0426 | 0.0234 | 0.0420 | 0.0137 | 0.0672 | 0.0206 | 0.8188 | 0.9295 | 0.0020 | 0.0068 | 0.0051 | 0.0228 | 0.0164 | 0.0387 | 0.0475 | 0.1048 | 0.0915 | 0.2096 | 0.1539 | 0.1891 | 0.1099 | 0.1071 | 0.1595 | 0.1344 | 0.4141 | 0.1868 | 0.0002 | 0.0041 | 0.0090 | 0.0124 | 0.0506 | 0.0812 | 0.0669 | 0.0846 | 0.6910 | 12 | 15 | 18 | 23 | 51 | 133 | 250 | 395 | 618 | 0.1321 | 29.66 | 4.846 | 0.5609 | 121307.0 | 98300000 | 95600000000 | 106000000000000 | 0.3068 | 0.3447 | 0.0442 | 0.0016 | 0.1546 | 0.0133 | 0.2155 | 0.0891 | 0.1482 | 0.1397 | 0.1751 | 0.1708 | 0.1401 | 0.1937 | 0.0636 | 0.1158 | 0.0442 | 0.1223 | 0.0145 | 0.1536 | 0.0006 | 0.0000 | 0.0012 | 0.0004 | 0.0031 | 0.0022 | 0.0115 | 0.0116 | 0.0386 | 0.0343 | 0.0571 | 0.0510 | 0.0451 | 0.0319 | 0.0658 | 0.0520 | 0.7769 | 0.8165 | 0.0007 | 0.0010 | 0.0026 | 0.0022 | 0.0043 | 0.0052 | 0.0155 | 0.0182 | 0.0500 | 0.0581 | 0.0812 | 0.0876 | 0.0644 | 0.0690 | 0.0894 | 0.1000 | 0.6918 | 0.6586 | 0.0002 | 0.0011 | 0.0040 | 0.0169 | 0.0395 | 0.0700 | 0.0579 | 0.0782 | 0.7322 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 699 | 471 | | 4304 | 9250 | 675.2 | 100.28 | 112.63 | 227.13 | 526 | 609 | 656 | 678 | 694 | 707 | 722 | 740 | 781 | 0.0782 | 723 | 1.058 | 105.04 | 31.11 | 1 | 0.0602 | 259 | 0.0017 | 29.52 | 6.816 | 0.2429 | 465980.0 | 327000000 | 234000000000 | 169000000000000 | 0.4313 | 0.2103 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0028 | 0.0000 | 0.0204 | 0.0139 | 0.0353 | 0.0238 | 0.0311 | 0.0120 | 0.0487 | 0.0205 | 0.8609 | 0.9297 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0149 | 0.0139 | 0.0259 | 0.0238 | 0.0191 | 0.0120 | 0.0254 | 0.0205 | 0.9130 | 0.9297 | 0.0082 | 0.0000 | 0.0163 | 0.0000 | 0.0245 | 0.0000 | 0.0367 | 0.0000 | 0.0816 | 0.0000 | 0.0857 | 0.0000 | 0.0816 | 0.0000 | 0.1143 | 0.0000 | 0.5510 | 0.0000 | 0.0004 | 0.0015 | 0.0038 | 0.0128 | 0.0342 | 0.0556 | 0.0680 | 0.0992 | 0.7244 | 8 | 10 | 12 | 14 | 17 | 26 | 59 | 148 | 341 | 0.1976 | 21.25 | 3.579 | 0.6813 | 64269.9 | 61100000 | 74500000000 | 106000000000000 | 0.4869 | 0.1485 | 0.0430 | 0.0000 | 0.1471 | 0.0171 | 0.1991 | 0.0910 | 0.1222 | 0.1229 | 0.1357 | 0.1456 | 0.1154 | 0.1581 | 0.1086 | 0.1229 | 0.0633 | 0.1024 | 0.0656 | 0.2400 | 0.0000 | 0.0000 | 0.0008 | 0.0004 | 0.0013 | 0.0011 | 0.0109 | 0.0094 | 0.0419 | 0.0410 | 0.0747 | 0.0556 | 0.0516 | 0.0402 | 0.0763 | 0.0676 | 0.7425 | 0.7847 | 0.0000 | 0.0006 | 0.0010 | 0.0022 | 0.0031 | 0.0028 | 0.0175 | 0.0185 | 0.0577 | 0.0612 | 0.0911 | 0.1021 | 0.0695 | 0.0606 | 0.0901 | 0.0948 | 0.6699 | 0.6571 | 0.0000 | 0.0009 | 0.0032 | 0.0125 | 0.0529 | 0.0779 | 0.0682 | 0.0904 | 0.6939 |