High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1130 | 460 | | 653 | 578 | 83.3 | 9.22 | 65.56 | 101.38 | 71 | 74 | 78 | 80 | 83 | 86 | 89 | 92 | 95 | 0.3910 | 226 | 0.478 | 77.79 | 11.31 | 1 | 0.3155 | 206 | 0.1159 | 0.55 | 2.394 | 0.7678 | 7017.7 | 598559 | 51600000 | 4510000000 | 0.4222 | 0.2132 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0065 | 0.0015 | 0.0455 | 0.0352 | 0.0698 | 0.0674 | 0.0779 | 0.0260 | 0.1347 | 0.0475 | 0.6623 | 0.8224 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0047 | 0.0015 | 0.0376 | 0.0352 | 0.0610 | 0.0674 | 0.0297 | 0.0260 | 0.0563 | 0.0475 | 0.8075 | 0.8224 | 0.1304 | 0.0000 | 0.3478 | 0.0000 | 0.2174 | 0.0000 | 0.1304 | 0.0000 | 0.0870 | 0.0000 | 0.0435 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0151 | 0.0211 | 0.0452 | 0.0994 | 0.0964 | 0.1325 | 0.1687 | 0.4187 | 7 | 10 | 13 | 18 | 24 | 35 | 52 | 90 | 200 | 0.0809 | 31.27 | 3.431 | 0.5091 | 14559.2 | 5410000 | 2520000000 | 1320000000000 | 0.5610 | 0.0846 | 0.2727 | 0.0094 | 0.5000 | 0.0377 | 0.2273 | 0.4151 | 0.0000 | 0.3396 | 0.0000 | 0.1038 | 0.0000 | 0.0849 | 0.0000 | 0.0094 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0405 | 0.0091 | 0.0173 | 0.0274 | 0.0347 | 0.0365 | 0.2023 | 0.1507 | 0.3410 | 0.3196 | 0.1676 | 0.1553 | 0.1850 | 0.1918 | 0.0116 | 0.1050 | 0.0155 | 0.0177 | 0.0233 | 0.0265 | 0.0698 | 0.0885 | 0.0853 | 0.0619 | 0.2636 | 0.3894 | 0.3488 | 0.3009 | 0.1860 | 0.1150 | 0.0078 | 0.0000 | 0.0000 | 0.0000 | 0.0134 | 0.0201 | 0.0336 | 0.0336 | 0.2282 | 0.3758 | 0.2013 | 0.0940 | 0.0000 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 902 | 486 | | 1571 | 8752 | 79.8 | 18.38 | 25.85 | 63.61 | 59 | 62 | 66 | 70 | 75 | 84 | 92 | 99 | 106 | 0.0978 | 856 | 0.759 | 104.01 | 24.21 | 3 | 0.1827 | 287 | 0.0137 | 2.82 | 4.627 | 0.5218 | 6709.4 | 592170 | 54600000 | 5230000000 | 0.4037 | 0.2309 | 0.0050 | 0.0000 | 0.0099 | 0.0000 | 0.0236 | 0.0000 | 0.0459 | 0.0067 | 0.0980 | 0.0299 | 0.1613 | 0.0552 | 0.1365 | 0.0579 | 0.1675 | 0.0685 | 0.3524 | 0.7818 | 0.0033 | 0.0000 | 0.0033 | 0.0000 | 0.0117 | 0.0000 | 0.0208 | 0.0045 | 0.0400 | 0.0248 | 0.0650 | 0.0446 | 0.0550 | 0.0299 | 0.0708 | 0.0350 | 0.7300 | 0.8611 | 0.0000 | 0.0299 | 0.0000 | 0.0746 | 0.0203 | 0.0597 | 0.0330 | 0.1642 | 0.0787 | 0.1045 | 0.1320 | 0.1493 | 0.1142 | 0.0746 | 0.1345 | 0.1194 | 0.4873 | 0.2239 | 0.0000 | 0.0057 | 0.0057 | 0.0213 | 0.0355 | 0.0682 | 0.0540 | 0.0753 | 0.7344 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 12 | 53 | 0.2949 | 7.14 | 2.200 | 0.6924 | 4714.0 | 1480000 | 590000000 | 281000000000 | 0.4076 | 0.1755 | 0.0603 | 0.0111 | 0.2915 | 0.0379 | 0.4824 | 0.1737 | 0.1407 | 0.2517 | 0.0101 | 0.2539 | 0.0101 | 0.1403 | 0.0050 | 0.0802 | 0.0000 | 0.0379 | 0.0000 | 0.0134 | 0.0008 | 0.0035 | 0.0041 | 0.0077 | 0.0154 | 0.0153 | 0.0170 | 0.0251 | 0.0519 | 0.0537 | 0.0787 | 0.0760 | 0.0463 | 0.0530 | 0.0779 | 0.0746 | 0.7078 | 0.6911 | 0.0019 | 0.0030 | 0.0039 | 0.0020 | 0.0048 | 0.0030 | 0.0087 | 0.0071 | 0.0571 | 0.0569 | 0.0871 | 0.0944 | 0.0600 | 0.0650 | 0.0794 | 0.0792 | 0.6970 | 0.6893 | 0.0018 | 0.0090 | 0.0045 | 0.0170 | 0.0502 | 0.0806 | 0.0556 | 0.0762 | 0.7052 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 688 | 724 | | 382 | 3170 | 111.2 | 49.61 | 43.27 | 125.08 | 45 | 55 | 71 | 91 | 111 | 133 | 151 | 163 | 177 | 0.1344 | 426 | 0.422 | 253.34 | 46.17 | 1 | 2.3037 | 880 | 0.0037 | 31.49 | 5.680 | 0.1888 | 14813.4 | 2190000 | 345000000 | 56300000000 | 0.2747 | 0.3491 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0057 | 0.2262 | 0.0345 | 0.3929 | 0.1379 | 0.2857 | 0.2184 | 0.0357 | 0.1494 | 0.0595 | 0.2184 | 0.0000 | 0.2356 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0085 | 0.0072 | 0.0681 | 0.0578 | 0.0851 | 0.0866 | 0.0511 | 0.0433 | 0.0681 | 0.0650 | 0.7191 | 0.7401 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0194 | 0.0927 | 0.1553 | 0.1192 | 0.1165 | 0.0397 | 0.0971 | 0.1060 | 0.1165 | 0.6424 | 0.4854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0733 | 0.1257 | 0.0314 | 0.0733 | 0.6963 | 7 | 8 | 9 | 10 | 10 | 11 | 12 | 15 | 33 | 0.6117 | 5.34 | 1.436 | 0.8850 | 17511.8 | 11000000 | 7740000000 | 5940000000000 | 0.6927 | 0.0495 | 0.0357 | 0.0000 | 0.1429 | 0.0385 | 0.2857 | 0.0641 | 0.2143 | 0.1538 | 0.1786 | 0.2436 | 0.1429 | 0.1923 | 0.0000 | 0.1154 | 0.0000 | 0.1538 | 0.0000 | 0.0385 | 0.0032 | 0.0000 | 0.0064 | 0.0085 | 0.0064 | 0.0141 | 0.0129 | 0.0226 | 0.0386 | 0.0621 | 0.0611 | 0.0424 | 0.0675 | 0.0621 | 0.0868 | 0.1017 | 0.7170 | 0.6864 | 0.0000 | 0.0000 | 0.0000 | 0.0036 | 0.0035 | 0.0000 | 0.0106 | 0.0181 | 0.0565 | 0.0471 | 0.0636 | 0.0870 | 0.0777 | 0.0725 | 0.0777 | 0.0725 | 0.7102 | 0.6993 | 0.0000 | 0.0000 | 0.0068 | 0.0102 | 0.0476 | 0.0612 | 0.0714 | 0.0884 | 0.7143 | ||
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 164 | 879 | | 4050 | 8872 | 419.4 | 110.73 | 86.10 | 234.18 | 295 | 334 | 362 | 385 | 409 | 439 | 474 | 515 | 570 | 0.0979 | 869 | 0.960 | 155.00 | 54.01 | 3 | 0.1049 | 425 | 0.0007 | 76.29 | 7.489 | 0.1602 | 188142.0 | 89200000 | 44400000000 | 23100000000000 | 0.4137 | 0.2255 | 0.0004 | 0.0000 | 0.0017 | 0.0000 | 0.0052 | 0.0000 | 0.0231 | 0.0043 | 0.0718 | 0.0210 | 0.1144 | 0.0459 | 0.1271 | 0.0397 | 0.1462 | 0.0559 | 0.5100 | 0.8333 | 0.0003 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0071 | 0.0013 | 0.0298 | 0.0149 | 0.0481 | 0.0238 | 0.0528 | 0.0149 | 0.0708 | 0.0245 | 0.7886 | 0.9206 | 0.0011 | 0.0000 | 0.0043 | 0.0099 | 0.0130 | 0.0099 | 0.0444 | 0.0759 | 0.0704 | 0.1452 | 0.1083 | 0.1716 | 0.0986 | 0.1089 | 0.1073 | 0.1584 | 0.5525 | 0.3201 | 0.0016 | 0.0032 | 0.0111 | 0.0185 | 0.0506 | 0.0749 | 0.0611 | 0.0870 | 0.6921 | 11 | 12 | 14 | 15 | 16 | 17 | 20 | 35 | 226 | 0.4982 | 14.49 | 2.220 | 0.8059 | 62249.3 | 81200000 | 135000000000 | 258000000000000 | 0.6303 | 0.0763 | 0.2131 | 0.0132 | 0.4262 | 0.1376 | 0.2295 | 0.3995 | 0.0546 | 0.1508 | 0.0546 | 0.1164 | 0.0219 | 0.1085 | 0.0000 | 0.0423 | 0.0000 | 0.0265 | 0.0000 | 0.0053 | 0.0007 | 0.0006 | 0.0055 | 0.0019 | 0.0097 | 0.0070 | 0.0194 | 0.0171 | 0.0947 | 0.0912 | 0.1418 | 0.1476 | 0.0705 | 0.0646 | 0.0961 | 0.0956 | 0.5615 | 0.5744 | 0.0008 | 0.0008 | 0.0032 | 0.0042 | 0.0071 | 0.0100 | 0.0301 | 0.0308 | 0.1013 | 0.1032 | 0.1362 | 0.1424 | 0.0831 | 0.0849 | 0.1077 | 0.1091 | 0.5305 | 0.5146 | 0.0022 | 0.0037 | 0.0066 | 0.0176 | 0.1051 | 0.1412 | 0.0713 | 0.1037 | 0.5485 |
| Hs 578T | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 79 | 365 | | 355 | 368 | 98.5 | 34.30 | 743.33 | 441.89 | 53 | 66 | 81 | 90 | 95 | 105 | 117 | 132 | 143 | 0.3995 | 147 | 1.183 | 36.12 | 15.52 | 1 | 0.2817 | 100 | 0.0040 | 43.26 | 5.614 | 0.2000 | 10879.1 | 1310000 | 169000000 | 22900000000 | 0.3710 | 0.2410 | 0.0000 | 0.0000 | 0.0265 | 0.0000 | 0.1060 | 0.0041 | 0.0927 | 0.0122 | 0.1258 | 0.1306 | 0.2053 | 0.1796 | 0.1589 | 0.1469 | 0.1126 | 0.1429 | 0.1722 | 0.3837 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0159 | 0.0067 | 0.0556 | 0.0669 | 0.1032 | 0.0635 | 0.0635 | 0.0535 | 0.1111 | 0.0702 | 0.6468 | 0.7391 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0297 | 0.1111 | 0.0792 | 0.2037 | 0.1386 | 0.2037 | 0.2673 | 0.2037 | 0.1287 | 0.1296 | 0.1287 | 0.1111 | 0.2277 | 0.0370 | 0.0000 | 0.0060 | 0.0060 | 0.0539 | 0.1257 | 0.1796 | 0.0958 | 0.1796 | 0.3533 | 167 | 338 | 432 | 575 | 717 | 837 | 975 | 1120 | 1332 | 0.0029 | 177.01 | 5.867 | 0.1008 | 747281.0 | 884000000 | 1170000000000 | 1.66E+15 | 0.3788 | 0.2356 | 0.0116 | 0.0127 | 0.1744 | 0.0570 | 0.2209 | 0.0633 | 0.2326 | 0.1266 | 0.1512 | 0.2089 | 0.1279 | 0.1835 | 0.0814 | 0.1835 | 0.0000 | 0.0886 | 0.0000 | 0.0759 | 0.0000 | 0.0040 | 0.0230 | 0.0199 | 0.0230 | 0.0199 | 0.0829 | 0.0598 | 0.1429 | 0.1474 | 0.1060 | 0.1235 | 0.1567 | 0.1474 | 0.1751 | 0.1633 | 0.2903 | 0.3147 | 0.0000 | 0.0000 | 0.0076 | 0.0108 | 0.0458 | 0.0323 | 0.0458 | 0.0860 | 0.2061 | 0.2688 | 0.1756 | 0.2151 | 0.1374 | 0.1720 | 0.2443 | 0.1828 | 0.1374 | 0.0323 | 0.0058 | 0.0173 | 0.0405 | 0.0578 | 0.1214 | 0.1445 | 0.1792 | 0.1850 | 0.2486 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1156 | 346 | | 318 | 920 | 14.3 | 4.68 | 5.30 | 2.36 | 9 | 10 | 12 | 13 | 14 | 14 | 16 | 17 | 21 | 0.2957 | 272 | 1.375 | 23.54 | 9.49 | 0 | 0.1855 | 59 | 0.0096 | 15.54 | 4.861 | 0.2753 | 224.9 | 3921.78 | 75133.4 | 1570000 | 0.3709 | 0.2571 | 0.0068 | 0.0000 | 0.0608 | 0.0000 | 0.0541 | 0.0000 | 0.1689 | 0.0498 | 0.2365 | 0.0805 | 0.1419 | 0.0958 | 0.1824 | 0.1149 | 0.1149 | 0.2835 | 0.0338 | 0.3755 | 0.0000 | 0.0000 | 0.0177 | 0.0000 | 0.0044 | 0.0000 | 0.0354 | 0.0301 | 0.1150 | 0.0569 | 0.0885 | 0.0535 | 0.1726 | 0.0635 | 0.1770 | 0.1639 | 0.3894 | 0.6321 | 0.0128 | 0.0789 | 0.0513 | 0.0526 | 0.0641 | 0.0263 | 0.0641 | 0.0526 | 0.1154 | 0.1842 | 0.1667 | 0.0789 | 0.1667 | 0.1579 | 0.1795 | 0.1842 | 0.1795 | 0.1842 | 0.0000 | 0.0248 | 0.0745 | 0.1056 | 0.1242 | 0.1242 | 0.1553 | 0.1553 | 0.2360 | 3 | 3 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0283 | 11.90 | 3.904 | 0.3091 | 33.7 | 240.012 | 1881.41 | 15989.2 | 0.5312 | 0.1181 | 0.1609 | 0.0033 | 0.2913 | 0.0384 | 0.3000 | 0.0801 | 0.1913 | 0.1436 | 0.0522 | 0.2053 | 0.0043 | 0.2354 | 0.0000 | 0.1803 | 0.0000 | 0.0835 | 0.0000 | 0.0301 | 0.0000 | 0.0000 | 0.0124 | 0.0000 | 0.0495 | 0.0132 | 0.1533 | 0.0444 | 0.2059 | 0.1187 | 0.2384 | 0.1007 | 0.2043 | 0.1775 | 0.1130 | 0.2818 | 0.0232 | 0.2638 | 0.0240 | 0.1277 | 0.0962 | 0.2681 | 0.2308 | 0.2766 | 0.2837 | 0.2383 | 0.2139 | 0.0766 | 0.1106 | 0.0128 | 0.0313 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0124 | 0.0496 | 0.1597 | 0.2031 | 0.2357 | 0.2031 | 0.1132 | 0.0233 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1211 | 385 | | 718 | 1212 | 13.2 | 2.76 | 5.21 | 2.35 | 10 | 11 | 12 | 12 | 13 | 14 | 15 | 16 | 17 | 0.2682 | 325 | 1.148 | 21.38 | 7.81 | 0 | 0.0822 | 59 | 0.0132 | 6.44 | 4.544 | 0.3693 | 180.9 | 2583.19 | 38202.1 | 582955 | 0.4010 | 0.2283 | 0.0000 | 0.0000 | 0.0157 | 0.0000 | 0.0449 | 0.0029 | 0.0966 | 0.0057 | 0.1483 | 0.0474 | 0.2000 | 0.0417 | 0.2337 | 0.0560 | 0.1775 | 0.1365 | 0.0831 | 0.7098 | 0.0000 | 0.0000 | 0.0034 | 0.0000 | 0.0168 | 0.0014 | 0.0387 | 0.0056 | 0.0505 | 0.0435 | 0.0640 | 0.0379 | 0.0993 | 0.0323 | 0.1465 | 0.0660 | 0.5808 | 0.8132 | 0.0604 | 0.3125 | 0.0537 | 0.0625 | 0.1141 | 0.2500 | 0.1342 | 0.3125 | 0.2550 | 0.0625 | 0.2081 | 0.0000 | 0.0738 | 0.0000 | 0.0738 | 0.0000 | 0.0268 | 0.0000 | 0.0097 | 0.0243 | 0.0511 | 0.0560 | 0.0779 | 0.1046 | 0.1192 | 0.2628 | 0.2944 | 2 | 3 | 3 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0284 | 12.09 | 3.933 | 0.3051 | 32.7 | 230.466 | 1783.27 | 14976.5 | 0.4758 | 0.1575 | 0.1219 | 0.0058 | 0.3000 | 0.0437 | 0.3188 | 0.1152 | 0.1688 | 0.2274 | 0.0719 | 0.2332 | 0.0188 | 0.1997 | 0.0000 | 0.1268 | 0.0000 | 0.0423 | 0.0000 | 0.0058 | 0.0000 | 0.0000 | 0.0159 | 0.0000 | 0.0684 | 0.0056 | 0.1233 | 0.0519 | 0.2320 | 0.0935 | 0.2527 | 0.1213 | 0.2002 | 0.2241 | 0.0867 | 0.2676 | 0.0208 | 0.2361 | 0.0281 | 0.0685 | 0.1563 | 0.1980 | 0.2184 | 0.2843 | 0.2926 | 0.2513 | 0.2084 | 0.1396 | 0.0782 | 0.0457 | 0.0160 | 0.0102 | 0.0020 | 0.0025 | 0.0000 | 0.0000 | 0.0000 | 0.0160 | 0.0688 | 0.1290 | 0.2359 | 0.2531 | 0.2015 | 0.0835 | 0.0123 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1179 | 272 | | 484 | 417 | 15.1 | 6.24 | 5.44 | 2.42 | 10 | 11 | 12 | 12 | 13 | 15 | 16 | 18 | 23 | 0.4964 | 207 | 0.834 | 37.74 | 12.04 | 0 | 0.2397 | 116 | 0.0096 | 14.01 | 4.972 | 0.3037 | 265.5 | 5621.95 | 142364 | 4170000 | 0.3690 | 0.2458 | 0.0041 | 0.0000 | 0.0207 | 0.0000 | 0.0664 | 0.0000 | 0.1660 | 0.0426 | 0.1618 | 0.0727 | 0.1826 | 0.1053 | 0.1826 | 0.1328 | 0.1369 | 0.1529 | 0.0788 | 0.4937 | 0.0000 | 0.0000 | 0.0146 | 0.0000 | 0.0292 | 0.0000 | 0.0437 | 0.0325 | 0.0787 | 0.0433 | 0.1108 | 0.0584 | 0.1224 | 0.0714 | 0.1866 | 0.0952 | 0.4140 | 0.6991 | 0.0392 | 0.0000 | 0.0392 | 0.0476 | 0.0686 | 0.0635 | 0.0490 | 0.0794 | 0.0784 | 0.1429 | 0.1961 | 0.1111 | 0.0980 | 0.1111 | 0.1275 | 0.1111 | 0.3039 | 0.3333 | 0.0051 | 0.0256 | 0.0718 | 0.0821 | 0.1026 | 0.1333 | 0.1385 | 0.1179 | 0.3231 | 3 | 3 | 4 | 5 | 5 | 7 | 7 | 7 | 9 | 0.0300 | 14.00 | 3.917 | 0.2952 | 35.4 | 257.772 | 2032.6 | 17052.4 | 0.3900 | 0.1941 | 0.1136 | 0.0290 | 0.2652 | 0.0773 | 0.2803 | 0.2174 | 0.1667 | 0.2560 | 0.0909 | 0.2029 | 0.0530 | 0.1353 | 0.0303 | 0.0628 | 0.0000 | 0.0145 | 0.0000 | 0.0048 | 0.0032 | 0.0000 | 0.0194 | 0.0079 | 0.0809 | 0.0159 | 0.1748 | 0.0714 | 0.2201 | 0.1720 | 0.2071 | 0.1746 | 0.1909 | 0.2302 | 0.0906 | 0.2169 | 0.0129 | 0.1111 | 0.0734 | 0.0760 | 0.1751 | 0.2047 | 0.3277 | 0.3392 | 0.2260 | 0.2222 | 0.1186 | 0.0877 | 0.0395 | 0.0292 | 0.0395 | 0.0409 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0072 | 0.0433 | 0.1300 | 0.2202 | 0.2238 | 0.1805 | 0.1336 | 0.0542 | 0.0072 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 665 | 315 | | 3881 | 7921 | 606.2 | 94.41 | 68.43 | 170.19 | 472 | 541 | 568 | 588 | 606 | 629 | 660 | 694 | 726 | 0.0917 | 726 | 0.976 | 112.07 | 42.38 | 2 | 0.0825 | 320 | 0.0014 | 32.18 | 6.910 | 0.2353 | 376420.0 | 239000000 | 154000000000 | 101000000000000 | 0.4392 | 0.1933 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0005 | 0.0345 | 0.0169 | 0.0495 | 0.0301 | 0.0505 | 0.0161 | 0.0697 | 0.0270 | 0.7890 | 0.9095 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0005 | 0.0212 | 0.0169 | 0.0256 | 0.0301 | 0.0206 | 0.0161 | 0.0317 | 0.0270 | 0.8986 | 0.9095 | 0.0054 | 0.0000 | 0.0161 | 0.0000 | 0.0215 | 0.0000 | 0.0538 | 0.0000 | 0.1048 | 0.0000 | 0.1532 | 0.0000 | 0.1183 | 0.0000 | 0.1263 | 0.0000 | 0.4005 | 0.0000 | 0.0031 | 0.0031 | 0.0097 | 0.0219 | 0.0429 | 0.0566 | 0.0536 | 0.0929 | 0.7163 | 5 | 6 | 7 | 9 | 10 | 11 | 14 | 30 | 209 | 0.1903 | 6.63 | 2.602 | 0.6219 | 33642.3 | 23500000 | 18600000000 | 16100000000000 | 0.5469 | 0.1234 | 0.0143 | 0.0118 | 0.2071 | 0.0059 | 0.2500 | 0.0710 | 0.2357 | 0.1154 | 0.2571 | 0.2308 | 0.0286 | 0.2337 | 0.0071 | 0.1834 | 0.0000 | 0.1065 | 0.0000 | 0.0414 | 0.0000 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0050 | 0.0119 | 0.0114 | 0.0500 | 0.0456 | 0.0738 | 0.0777 | 0.0484 | 0.0428 | 0.0745 | 0.0720 | 0.7407 | 0.7418 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0009 | 0.0089 | 0.0132 | 0.0526 | 0.0545 | 0.0847 | 0.0771 | 0.0455 | 0.0526 | 0.0794 | 0.0808 | 0.7279 | 0.7209 | 0.0000 | 0.0000 | 0.0017 | 0.0093 | 0.0499 | 0.0854 | 0.0448 | 0.0761 | 0.7327 | ||
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 706 | 476 | | 728 | 1022 | 96.1 | 32.97 | 217.29 | 252.33 | 64 | 70 | 76 | 81 | 87 | 93 | 104 | 119 | 143 | 0.2652 | 271 | 0.410 | 145.45 | 41.40 | 1 | 0.7843 | 571 | 0.0039 | 22.73 | 5.781 | 0.2516 | 10321.1 | 1250000 | 169000000 | 25300000000 | 0.4351 | 0.2119 | 0.0000 | 0.0000 | 0.0173 | 0.0066 | 0.0202 | 0.0099 | 0.0980 | 0.0066 | 0.2161 | 0.0724 | 0.2017 | 0.0938 | 0.2017 | 0.0674 | 0.1441 | 0.1628 | 0.1009 | 0.5806 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0296 | 0.0029 | 0.1006 | 0.0471 | 0.1381 | 0.0799 | 0.1282 | 0.0428 | 0.1440 | 0.1084 | 0.4576 | 0.7190 | 0.0000 | 0.0215 | 0.0000 | 0.0000 | 0.0375 | 0.0000 | 0.0625 | 0.0753 | 0.1438 | 0.1183 | 0.1563 | 0.1720 | 0.1063 | 0.2151 | 0.1438 | 0.1398 | 0.3500 | 0.2581 | 0.0037 | 0.0000 | 0.0112 | 0.0669 | 0.1227 | 0.1450 | 0.0558 | 0.1004 | 0.4944 | 18 | 22 | 28 | 45 | 88 | 168 | 297 | 431 | 602 | 0.0497 | 49.53 | 4.975 | 0.4355 | 110822.0 | 73200000 | 55400000000 | 45800000000000 | 0.5813 | 0.0827 | 0.1029 | 0.0000 | 0.2500 | 0.0581 | 0.3971 | 0.1806 | 0.1324 | 0.2581 | 0.0735 | 0.2387 | 0.0147 | 0.1355 | 0.0294 | 0.0774 | 0.0000 | 0.0387 | 0.0000 | 0.0129 | 0.0000 | 0.0000 | 0.0050 | 0.0022 | 0.0074 | 0.0022 | 0.0074 | 0.0285 | 0.0695 | 0.0724 | 0.1390 | 0.1162 | 0.0893 | 0.0943 | 0.1216 | 0.1250 | 0.5608 | 0.5592 | 0.0000 | 0.0000 | 0.0000 | 0.0033 | 0.0090 | 0.0000 | 0.0090 | 0.0233 | 0.0746 | 0.0731 | 0.1731 | 0.1728 | 0.0836 | 0.1163 | 0.1313 | 0.1262 | 0.5194 | 0.4851 | 0.0000 | 0.0000 | 0.0028 | 0.0110 | 0.0579 | 0.1818 | 0.0661 | 0.1350 | 0.5455 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 568 | 142 | | 3390 | 3676 | 488.2 | 76.89 | 55.99 | 95.47 | 384 | 420 | 448 | 473 | 493 | 513 | 533 | 556 | 587 | 0.1317 | 484 | 0.859 | 109.18 | 23.32 | 5 | 0.0752 | 255 | 0.0012 | 41.51 | 6.959 | 0.2091 | 244289.0 | 125000000 | 65200000000 | 34600000000000 | 0.4456 | 0.2022 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0133 | 0.0009 | 0.0451 | 0.0139 | 0.0863 | 0.0237 | 0.0833 | 0.0160 | 0.1064 | 0.0261 | 0.6638 | 0.9194 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0050 | 0.0009 | 0.0220 | 0.0139 | 0.0441 | 0.0237 | 0.0414 | 0.0154 | 0.0588 | 0.0231 | 0.8284 | 0.9230 | 0.0028 | 0.0000 | 0.0113 | 1.0000 | 0.0395 | 0.0000 | 0.1073 | 0.0000 | 0.1638 | 0.0000 | 0.2147 | 0.0000 | 0.1243 | 0.0000 | 0.1356 | 0.0000 | 0.2006 | 0.0000 | 0.0006 | 0.0017 | 0.0045 | 0.0195 | 0.0658 | 0.1155 | 0.1016 | 0.1267 | 0.5642 | 9 | 11 | 12 | 14 | 17 | 20 | 25 | 75 | 169 | 0.1554 | 6.68 | 3.147 | 0.7267 | 12247.2 | 4240000 | 1770000000 | 834000000000 | 0.4752 | 0.1492 | 0.0192 | 0.0284 | 0.0769 | 0.0355 | 0.1731 | 0.1277 | 0.3462 | 0.1489 | 0.1346 | 0.1915 | 0.1346 | 0.1773 | 0.1154 | 0.1206 | 0.0000 | 0.0709 | 0.0000 | 0.0993 | 0.0000 | 0.0046 | 0.0025 | 0.0058 | 0.0012 | 0.0116 | 0.0037 | 0.0127 | 0.0160 | 0.0197 | 0.0197 | 0.0313 | 0.0271 | 0.0174 | 0.0406 | 0.0440 | 0.8892 | 0.8530 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0028 | 0.0039 | 0.0083 | 0.0211 | 0.0221 | 0.0316 | 0.0456 | 0.0395 | 0.0415 | 0.0684 | 0.0692 | 0.8329 | 0.8105 | 0.0000 | 0.0000 | 0.0013 | 0.0038 | 0.0189 | 0.0215 | 0.0278 | 0.0556 | 0.8712 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 524 | 141 | | 4317 | 6246 | 463.8 | 114.50 | 71.69 | 106.41 | 339 | 369 | 392 | 415 | 440 | 467 | 500 | 549 | 629 | 0.1005 | 628 | 1.211 | 95.02 | 37.48 | 1 | 0.0563 | 243 | 0.0011 | 40.02 | 7.058 | 0.1884 | 228193.0 | 119000000 | 66600000000 | 39500000000000 | 0.3905 | 0.2504 | 0.0000 | 0.0000 | 0.0012 | 0.0005 | 0.0054 | 0.0005 | 0.0173 | 0.0033 | 0.0695 | 0.0228 | 0.1245 | 0.0415 | 0.1318 | 0.0400 | 0.1690 | 0.0488 | 0.4814 | 0.8426 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0026 | 0.0000 | 0.0076 | 0.0009 | 0.0334 | 0.0140 | 0.0577 | 0.0244 | 0.0633 | 0.0147 | 0.0882 | 0.0216 | 0.7466 | 0.9244 | 0.0037 | 0.0000 | 0.0049 | 0.0057 | 0.0099 | 0.0345 | 0.0469 | 0.0690 | 0.0877 | 0.1293 | 0.1395 | 0.1264 | 0.1025 | 0.1264 | 0.1173 | 0.1494 | 0.4877 | 0.3592 | 0.0006 | 0.0051 | 0.0130 | 0.0395 | 0.0745 | 0.1072 | 0.0874 | 0.0987 | 0.5742 | 7 | 10 | 12 | 15 | 21 | 31 | 56 | 127 | 227 | 0.0902 | 12.13 | 4.224 | 0.6055 | 16459.4 | 5640000 | 2380000000 | 1160000000000 | 0.4828 | 0.1513 | 0.0532 | 0.0047 | 0.1894 | 0.0235 | 0.2990 | 0.0691 | 0.2359 | 0.1821 | 0.1196 | 0.2323 | 0.0698 | 0.2276 | 0.0266 | 0.1366 | 0.0000 | 0.0754 | 0.0066 | 0.0487 | 0.0000 | 0.0014 | 0.0000 | 0.0014 | 0.0022 | 0.0039 | 0.0129 | 0.0082 | 0.0533 | 0.0488 | 0.0787 | 0.0768 | 0.0566 | 0.0497 | 0.0981 | 0.0888 | 0.6983 | 0.7209 | 0.0000 | 0.0000 | 0.0013 | 0.0021 | 0.0058 | 0.0077 | 0.0154 | 0.0112 | 0.0624 | 0.0732 | 0.0977 | 0.0962 | 0.0585 | 0.0635 | 0.1145 | 0.1123 | 0.6444 | 0.6339 | 0.0000 | 0.0018 | 0.0035 | 0.0183 | 0.0589 | 0.0796 | 0.0654 | 0.0961 | 0.6765 | ||
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 895 | 609 | | 4883 | 16388 | 528.4 | 82.82 | 129.28 | 239.46 | 424 | 462 | 486 | 505 | 525 | 545 | 568 | 595 | 639 | 0.0616 | 1009 | 0.725 | 104.48 | 25.55 | 1 | 0.0555 | 271 | 0.0023 | 18.30 | 6.393 | 0.2729 | 286071.0 | 158000000 | 89700000000 | 51900000000000 | 0.4173 | 0.2298 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0000 | 0.0054 | 0.0004 | 0.0293 | 0.0147 | 0.0673 | 0.0263 | 0.0671 | 0.0165 | 0.1041 | 0.0296 | 0.7248 | 0.9125 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0004 | 0.0181 | 0.0138 | 0.0331 | 0.0232 | 0.0342 | 0.0135 | 0.0512 | 0.0220 | 0.8611 | 0.9271 | 0.0036 | 0.0000 | 0.0018 | 0.0000 | 0.0309 | 0.0882 | 0.0436 | 0.2353 | 0.1291 | 0.2941 | 0.1673 | 0.0882 | 0.0800 | 0.1765 | 0.1436 | 0.0882 | 0.4000 | 0.0294 | 0.0013 | 0.0051 | 0.0131 | 0.0300 | 0.0656 | 0.1016 | 0.0863 | 0.1121 | 0.5849 | 7 | 9 | 10 | 11 | 13 | 18 | 55 | 222 | 459 | 0.2514 | 33.66 | 3.796 | 0.6421 | 74049.5 | 59100000 | 55800000000 | 58800000000000 | 0.5654 | 0.1070 | 0.1457 | 0.0103 | 0.2870 | 0.0432 | 0.3576 | 0.2613 | 0.1369 | 0.2469 | 0.0397 | 0.2171 | 0.0221 | 0.1235 | 0.0110 | 0.0463 | 0.0000 | 0.0267 | 0.0000 | 0.0247 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0009 | 0.0004 | 0.0085 | 0.0063 | 0.0461 | 0.0469 | 0.0811 | 0.0735 | 0.0507 | 0.0480 | 0.0726 | 0.0676 | 0.7401 | 0.7571 | 0.0000 | 0.0003 | 0.0005 | 0.0000 | 0.0013 | 0.0030 | 0.0108 | 0.0120 | 0.0569 | 0.0569 | 0.0857 | 0.0867 | 0.0607 | 0.0684 | 0.0810 | 0.0878 | 0.7031 | 0.6848 | 0.0000 | 0.0000 | 0.0005 | 0.0097 | 0.0508 | 0.0832 | 0.0557 | 0.0735 | 0.7266 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 644 | 300 | | 381 | 806 | 12.1 | 3.51 | 5.40 | 1.98 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 17 | 0.3623 | 292 | 0.804 | 32.02 | 8.25 | 0 | 0.2283 | 87 | 0.0100 | 11.54 | 4.797 | 0.2819 | 158.7 | 2234.75 | 33514.1 | 530731 | 0.4187 | 0.2080 | 0.0000 | 0.0000 | 0.0459 | 0.0000 | 0.1429 | 0.0033 | 0.1837 | 0.0262 | 0.2143 | 0.1082 | 0.2245 | 0.1934 | 0.1071 | 0.1836 | 0.0663 | 0.2787 | 0.0153 | 0.2066 | 0.0000 | 0.0000 | 0.0179 | 0.0000 | 0.0286 | 0.0000 | 0.0536 | 0.0143 | 0.0929 | 0.0602 | 0.1071 | 0.0659 | 0.1464 | 0.1347 | 0.1929 | 0.2063 | 0.3607 | 0.5186 | 0.0238 | 0.0682 | 0.1310 | 0.2045 | 0.1310 | 0.1136 | 0.2262 | 0.1591 | 0.1667 | 0.1364 | 0.1548 | 0.2273 | 0.0595 | 0.0455 | 0.0833 | 0.0455 | 0.0238 | 0.0000 | 0.0094 | 0.0330 | 0.0377 | 0.0566 | 0.1226 | 0.1509 | 0.1462 | 0.2217 | 0.2217 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0262 | 8.53 | 4.026 | 0.3635 | 33.1 | 222.937 | 1630.58 | 12844 | 0.5218 | 0.1301 | 0.0340 | 0.0037 | 0.1671 | 0.0201 | 0.2125 | 0.0713 | 0.2351 | 0.1755 | 0.2153 | 0.2194 | 0.0963 | 0.2102 | 0.0397 | 0.1481 | 0.0000 | 0.1097 | 0.0000 | 0.0420 | 0.0014 | 0.0013 | 0.0029 | 0.0000 | 0.0203 | 0.0053 | 0.0695 | 0.0420 | 0.1462 | 0.1183 | 0.1650 | 0.1367 | 0.1838 | 0.1380 | 0.2489 | 0.2076 | 0.1621 | 0.3509 | 0.0355 | 0.1308 | 0.1450 | 0.2664 | 0.2367 | 0.2617 | 0.2426 | 0.1215 | 0.1538 | 0.1308 | 0.0947 | 0.0607 | 0.0562 | 0.0187 | 0.0266 | 0.0000 | 0.0089 | 0.0093 | 0.0018 | 0.0235 | 0.0868 | 0.1374 | 0.1953 | 0.2441 | 0.2080 | 0.0759 | 0.0271 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1131 | 915 | | 2089 | 9754 | 430.7 | 88.27 | 4.29 | 2.29 | 312 | 347 | 379 | 402 | 426 | 453 | 480 | 511 | 554 | 0.0779 | 760 | 1.256 | 68.26 | 30.41 | 1 | 0.0881 | 184 | 0.0020 | 13.39 | 6.433 | 0.2835 | 193252.0 | 90100000 | 43400000000 | 21600000000000 | 0.4117 | 0.2216 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0069 | 0.0010 | 0.0138 | 0.0020 | 0.0535 | 0.0221 | 0.0680 | 0.0432 | 0.0688 | 0.0285 | 0.1016 | 0.0569 | 0.6845 | 0.8464 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0053 | 0.0005 | 0.0065 | 0.0005 | 0.0213 | 0.0187 | 0.0296 | 0.0360 | 0.0260 | 0.0149 | 0.0391 | 0.0316 | 0.8704 | 0.8979 | 0.0000 | 0.0417 | 0.0026 | 0.1042 | 0.0236 | 0.1042 | 0.0289 | 0.1458 | 0.0735 | 0.2083 | 0.0997 | 0.0833 | 0.0919 | 0.1458 | 0.1102 | 0.1250 | 0.5696 | 0.0417 | 0.0020 | 0.0000 | 0.0059 | 0.0129 | 0.0287 | 0.0416 | 0.0505 | 0.0921 | 0.7663 | 2 | 2 | 3 | 3 | 4 | 5 | 5 | 6 | 7 | 0.1846 | 0.51 | 1.036 | 0.4874 | 23.6 | 149.049 | 1043.77 | 7945.36 | 0.5246 | 0.1474 | 0.1109 | 0.0066 | 0.1934 | 0.0403 | 0.2941 | 0.1203 | 0.2455 | 0.1990 | 0.0984 | 0.2637 | 0.0452 | 0.2180 | 0.0124 | 0.1183 | 0.0000 | 0.0305 | 0.0000 | 0.0032 | 0.0060 | 0.0000 | 0.0262 | 0.0025 | 0.0778 | 0.0134 | 0.1544 | 0.0375 | 0.2136 | 0.0942 | 0.2173 | 0.1639 | 0.1817 | 0.2530 | 0.0965 | 0.2739 | 0.0264 | 0.1617 | 0.0166 | 0.0996 | 0.0561 | 0.2292 | 0.1352 | 0.2826 | 0.2123 | 0.2167 | 0.2213 | 0.1091 | 0.1892 | 0.0477 | 0.1151 | 0.0125 | 0.0451 | 0.0027 | 0.0090 | 0.0000 | 0.0060 | 0.0262 | 0.0778 | 0.1544 | 0.2136 | 0.2173 | 0.1817 | 0.0965 | 0.0264 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1200 | 960 | | 312 | 3292 | 82.5 | 11.29 | 23.21 | 72.43 | 68 | 73 | 76 | 79 | 82 | 86 | 89 | 93 | 97 | 0.1206 | 397 | 1.136 | 33.29 | 11.66 | 2 | 0.2724 | 85 | 0.0754 | 0.90 | 2.811 | 0.6827 | 6932.2 | 592793 | 51500000 | 4550000000 | 0.3990 | 0.2389 | 0.0037 | 0.0000 | 0.0000 | 0.0032 | 0.0112 | 0.0000 | 0.0485 | 0.0096 | 0.0672 | 0.0737 | 0.1194 | 0.0833 | 0.0933 | 0.0481 | 0.1604 | 0.0705 | 0.4963 | 0.7115 | 0.0034 | 0.0000 | 0.0000 | 0.0032 | 0.0069 | 0.0000 | 0.0206 | 0.0096 | 0.0481 | 0.0737 | 0.0997 | 0.0833 | 0.0378 | 0.0481 | 0.0722 | 0.0705 | 0.7113 | 0.7115 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.2174 | 0.0000 | 0.2609 | 0.0000 | 0.0870 | 0.0000 | 0.1304 | 0.0000 | 0.0435 | 0.0000 | 0.0000 | 0.0000 | 0.0435 | 0.0000 | 0.0120 | 0.0180 | 0.0299 | 0.0539 | 0.0898 | 0.2275 | 0.0958 | 0.1078 | 0.3653 | 5 | 6 | 8 | 8 | 9 | 10 | 11 | 12 | 16 | 0.2788 | 2.99 | 1.539 | 0.6666 | 5783.0 | 2740000 | 1470000000 | 851000000000 | 0.3576 | 0.2571 | 0.1333 | 0.2774 | 0.2167 | 0.1473 | 0.3500 | 0.1130 | 0.1833 | 0.1541 | 0.0833 | 0.1336 | 0.0333 | 0.1199 | 0.0000 | 0.0411 | 0.0000 | 0.0103 | 0.0000 | 0.0034 | 0.0217 | 0.1656 | 0.0072 | 0.0879 | 0.0109 | 0.0573 | 0.0217 | 0.0613 | 0.0435 | 0.0327 | 0.0942 | 0.0675 | 0.0471 | 0.0409 | 0.0870 | 0.0695 | 0.6667 | 0.4172 | 0.0000 | 0.0000 | 0.0093 | 0.0000 | 0.0046 | 0.0000 | 0.0139 | 0.0203 | 0.0509 | 0.0711 | 0.1111 | 0.0863 | 0.0556 | 0.0761 | 0.0787 | 0.0863 | 0.6759 | 0.6599 | 0.0042 | 0.0042 | 0.0211 | 0.0253 | 0.0506 | 0.0717 | 0.0717 | 0.0928 | 0.6582 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1120 | 374 | | 1013 | 7639 | 932.9 | 280.82 | 18.77 | 68.99 | 520 | 632 | 745 | 866 | 972 | 1068 | 1154 | 1217 | 1274 | 0.0730 | 558 | 0.951 | 63.01 | 16.64 | 2 | 0.1382 | 140 | 0.0016 | 66.58 | 6.568 | 0.1620 | 949022.0 | 1030000000 | 1160000000000 | 1.34E+15 | 0.2997 | 0.3332 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0013 | 0.0141 | 0.0025 | 0.1155 | 0.0401 | 0.2197 | 0.0877 | 0.1380 | 0.0401 | 0.1662 | 0.0677 | 0.3437 | 0.7607 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0000 | 0.0368 | 0.0311 | 0.0637 | 0.0681 | 0.0326 | 0.0219 | 0.0425 | 0.0381 | 0.8201 | 0.8408 | 0.0000 | 0.0000 | 0.0000 | 0.0145 | 0.0000 | 0.0000 | 0.0171 | 0.0580 | 0.0484 | 0.1449 | 0.0883 | 0.1014 | 0.0570 | 0.1014 | 0.0712 | 0.2029 | 0.7179 | 0.3768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0427 | 0.0816 | 0.0278 | 0.0594 | 0.7885 | 4 | 5 | 6 | 6 | 8 | 8 | 9 | 11 | 13 | 0.1323 | 2.99 | 1.460 | 0.4553 | 5111.7 | 3110000 | 2280000000 | 1870000000000 | 0.4103 | 0.1711 | 0.2687 | 0.1623 | 0.2463 | 0.1455 | 0.2015 | 0.1545 | 0.2612 | 0.1636 | 0.0224 | 0.1325 | 0.0000 | 0.1273 | 0.0000 | 0.0688 | 0.0000 | 0.0416 | 0.0000 | 0.0039 | 0.0357 | 0.1050 | 0.0187 | 0.0915 | 0.0221 | 0.0882 | 0.0306 | 0.0747 | 0.0629 | 0.0571 | 0.0510 | 0.0756 | 0.0952 | 0.0655 | 0.0799 | 0.0756 | 0.6037 | 0.3669 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0066 | 0.0000 | 0.0176 | 0.0143 | 0.0683 | 0.0903 | 0.1101 | 0.1021 | 0.0551 | 0.0570 | 0.0991 | 0.1069 | 0.6410 | 0.6295 | 0.0100 | 0.0060 | 0.0040 | 0.0260 | 0.0680 | 0.0820 | 0.0740 | 0.0900 | 0.6400 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1243 | 854 | | 722 | 7966 | 63.7 | 17.26 | 99.18 | 192.37 | 47 | 51 | 53 | 56 | 60 | 63 | 68 | 74 | 85 | 0.0734 | 585 | 0.421 | 183.11 | 37.80 | 0 | 0.8726 | 630 | 0.0093 | 10.56 | 5.018 | 0.3434 | 4360.7 | 324711 | 26600000 | 2420000000 | 0.4665 | 0.1732 | 0.0048 | 0.0000 | 0.0238 | 0.0000 | 0.0499 | 0.0060 | 0.0950 | 0.0255 | 0.1354 | 0.0510 | 0.1853 | 0.0990 | 0.1663 | 0.1049 | 0.1663 | 0.1094 | 0.1734 | 0.6042 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0128 | 0.0028 | 0.0475 | 0.0097 | 0.0786 | 0.0444 | 0.1408 | 0.0819 | 0.1261 | 0.0611 | 0.1481 | 0.0833 | 0.4388 | 0.7167 | 0.0000 | 0.0000 | 0.0317 | 0.0377 | 0.0159 | 0.0755 | 0.0952 | 0.0755 | 0.1825 | 0.3019 | 0.1825 | 0.1321 | 0.1508 | 0.0566 | 0.1508 | 0.2075 | 0.1905 | 0.1132 | 0.0036 | 0.0180 | 0.0288 | 0.0791 | 0.1259 | 0.1691 | 0.1295 | 0.1511 | 0.2950 | 10 | 12 | 14 | 15 | 17 | 19 | 31 | 113 | 371 | 0.1151 | 73.14 | 4.084 | 0.5429 | 46837.2 | 32700000 | 27500000000 | 26300000000000 | 0.6007 | 0.1115 | 0.2664 | 0.0211 | 0.4953 | 0.1607 | 0.2103 | 0.5011 | 0.0280 | 0.1882 | 0.0000 | 0.0782 | 0.0000 | 0.0338 | 0.0000 | 0.0127 | 0.0000 | 0.0042 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0022 | 0.0015 | 0.0056 | 0.0036 | 0.0185 | 0.0247 | 0.0888 | 0.0781 | 0.1355 | 0.1183 | 0.0748 | 0.0848 | 0.1231 | 0.1177 | 0.5509 | 0.5707 | 0.0006 | 0.0007 | 0.0013 | 0.0041 | 0.0083 | 0.0082 | 0.0230 | 0.0211 | 0.0856 | 0.0958 | 0.1540 | 0.1501 | 0.0818 | 0.0795 | 0.1176 | 0.1291 | 0.5278 | 0.5115 | 0.0012 | 0.0024 | 0.0054 | 0.0198 | 0.0929 | 0.1360 | 0.0827 | 0.1210 | 0.5386 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1235 | 928 | | 3908 | 866 | 131.6 | 35.52 | 83.99 | 75.24 | 92 | 104 | 113 | 120 | 128 | 134 | 143 | 154 | 171 | 0.5855 | 507 | 1.261 | 98.62 | 31.32 | 1 | 0.0581 | 227 | 0.0023 | 24.71 | 6.369 | 0.2431 | 18576.3 | 2850000 | 480000000 | 90700000000 | 0.4962 | 0.1800 | 0.0025 | 0.0000 | 0.0025 | 0.0003 | 0.0091 | 0.0020 | 0.0313 | 0.0045 | 0.0844 | 0.0247 | 0.1671 | 0.0656 | 0.1560 | 0.0617 | 0.1844 | 0.1041 | 0.3627 | 0.7372 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0016 | 0.0107 | 0.0024 | 0.0488 | 0.0200 | 0.0837 | 0.0431 | 0.0755 | 0.0318 | 0.1153 | 0.0568 | 0.6620 | 0.8442 | 0.0109 | 0.0207 | 0.0125 | 0.0290 | 0.0498 | 0.0290 | 0.0888 | 0.1079 | 0.1495 | 0.1992 | 0.1947 | 0.1826 | 0.1137 | 0.0747 | 0.1340 | 0.1452 | 0.2461 | 0.2116 | 0.0012 | 0.0075 | 0.0184 | 0.0519 | 0.1308 | 0.1360 | 0.1314 | 0.1527 | 0.3700 | 16 | 24 | 36 | 50 | 62 | 79 | 105 | 130 | 176 | 0.0070 | 32.32 | 5.471 | 0.3545 | 12708.8 | 3020000 | 1050000000 | 473000000000 | 0.5943 | 0.0759 | 0.0880 | 0.0099 | 0.2240 | 0.0627 | 0.2160 | 0.0924 | 0.2480 | 0.1881 | 0.1600 | 0.2277 | 0.0560 | 0.2376 | 0.0080 | 0.0792 | 0.0000 | 0.0528 | 0.0000 | 0.0495 | 0.0150 | 0.0019 | 0.0200 | 0.0174 | 0.0324 | 0.0174 | 0.0549 | 0.0581 | 0.2893 | 0.2364 | 0.3566 | 0.3682 | 0.1322 | 0.1492 | 0.0574 | 0.0717 | 0.0424 | 0.0795 | 0.0072 | 0.0047 | 0.0217 | 0.0235 | 0.0580 | 0.0798 | 0.1051 | 0.1221 | 0.2754 | 0.2864 | 0.3370 | 0.3146 | 0.1123 | 0.0986 | 0.0507 | 0.0376 | 0.0326 | 0.0329 | 0.0151 | 0.0151 | 0.0272 | 0.1057 | 0.2779 | 0.3595 | 0.1178 | 0.0453 | 0.0363 | ||
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 95 | 131 | | 989 | 1640 | 89.4 | 13.84 | 29.47 | 62.84 | 71 | 77 | 82 | 85 | 89 | 93 | 96 | 101 | 107 | 0.2116 | 347 | 0.177 | 169.76 | 32.53 | 2 | 0.8817 | 872 | 0.0651 | 1.08 | 3.063 | 0.6829 | 8181.5 | 766522 | 73500000 | 7210000000 | 0.3997 | 0.2450 | 0.0013 | 0.0000 | 0.0025 | 0.0000 | 0.0063 | 0.0000 | 0.0304 | 0.0061 | 0.0608 | 0.0348 | 0.0989 | 0.0583 | 0.1343 | 0.0409 | 0.1926 | 0.0502 | 0.4728 | 0.8096 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0022 | 0.0000 | 0.0169 | 0.0051 | 0.0371 | 0.0293 | 0.0573 | 0.0526 | 0.0629 | 0.0303 | 0.0843 | 0.0415 | 0.7371 | 0.8413 | 0.0594 | 0.0000 | 0.1089 | 0.3333 | 0.1188 | 0.2500 | 0.1485 | 0.2500 | 0.1485 | 0.0833 | 0.1782 | 0.0833 | 0.0594 | 0.0000 | 0.0792 | 0.0000 | 0.0990 | 0.0000 | 0.0019 | 0.0077 | 0.0232 | 0.0522 | 0.0754 | 0.1006 | 0.1528 | 0.2147 | 0.3714 | 8 | 10 | 12 | 13 | 15 | 17 | 20 | 26 | 43 | 0.3370 | 1.57 | 1.900 | 0.7940 | 4815.1 | 2160000 | 1340000000 | 961000000000 | 0.6590 | 0.0663 | 0.0476 | 0.0571 | 0.1429 | 0.0571 | 0.1905 | 0.0813 | 0.2434 | 0.1099 | 0.2487 | 0.1429 | 0.0794 | 0.1868 | 0.0476 | 0.1890 | 0.0000 | 0.1341 | 0.0000 | 0.0418 | 0.0128 | 0.0413 | 0.0434 | 0.0366 | 0.0561 | 0.0461 | 0.0918 | 0.0636 | 0.1429 | 0.0986 | 0.1709 | 0.1574 | 0.1301 | 0.1558 | 0.1071 | 0.1558 | 0.2449 | 0.2448 | 0.0246 | 0.0057 | 0.0148 | 0.0230 | 0.0296 | 0.0345 | 0.0788 | 0.0575 | 0.1478 | 0.1609 | 0.1773 | 0.2126 | 0.1281 | 0.1149 | 0.1232 | 0.1437 | 0.2759 | 0.2471 | 0.0223 | 0.0335 | 0.0520 | 0.0632 | 0.1561 | 0.1710 | 0.1227 | 0.1190 | 0.2602 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 533 | 682 | | 7313 | 29998 | 383.9 | 96.67 | 156.93 | 277.72 | 269 | 302 | 327 | 350 | 372 | 397 | 429 | 467 | 513 | 0.0399 | 1198 | 1.208 | 132.80 | 56.82 | 1 | 0.0483 | 353 | 0.0008 | 42.70 | 7.362 | 0.1796 | 156719.0 | 67700000 | 30900000000 | 14700000000000 | 0.4294 | 0.2186 | 0.0000 | 0.0002 | 0.0019 | 0.0000 | 0.0056 | 0.0006 | 0.0223 | 0.0032 | 0.0776 | 0.0240 | 0.1395 | 0.0531 | 0.1380 | 0.0451 | 0.1584 | 0.0649 | 0.4567 | 0.8089 | 0.0000 | 0.0001 | 0.0011 | 0.0000 | 0.0023 | 0.0003 | 0.0074 | 0.0016 | 0.0342 | 0.0155 | 0.0598 | 0.0314 | 0.0600 | 0.0208 | 0.0798 | 0.0327 | 0.7556 | 0.8977 | 0.0032 | 0.0056 | 0.0051 | 0.0093 | 0.0051 | 0.0075 | 0.0329 | 0.0746 | 0.0981 | 0.1362 | 0.1253 | 0.2034 | 0.1101 | 0.1063 | 0.1380 | 0.1716 | 0.4823 | 0.2854 | 0.0003 | 0.0015 | 0.0075 | 0.0301 | 0.0733 | 0.1004 | 0.0869 | 0.1025 | 0.5975 | 8 | 9 | 11 | 12 | 15 | 25 | 92 | 285 | 569 | 0.2355 | 33.94 | 3.958 | 0.6313 | 101753.0 | 91200000 | 98600000000 | 124000000000000 | 0.4779 | 0.1557 | 0.1073 | 0.0081 | 0.3320 | 0.0585 | 0.3330 | 0.2590 | 0.1394 | 0.2001 | 0.0471 | 0.2020 | 0.0301 | 0.1388 | 0.0090 | 0.0741 | 0.0020 | 0.0371 | 0.0000 | 0.0223 | 0.0002 | 0.0004 | 0.0006 | 0.0011 | 0.0008 | 0.0010 | 0.0076 | 0.0093 | 0.0425 | 0.0390 | 0.0726 | 0.0654 | 0.0486 | 0.0443 | 0.0803 | 0.0682 | 0.7467 | 0.7711 | 0.0001 | 0.0001 | 0.0004 | 0.0000 | 0.0019 | 0.0013 | 0.0107 | 0.0116 | 0.0477 | 0.0518 | 0.0894 | 0.1012 | 0.0658 | 0.0667 | 0.0972 | 0.1078 | 0.6868 | 0.6595 | 0.0000 | 0.0005 | 0.0009 | 0.0099 | 0.0457 | 0.0788 | 0.0566 | 0.0902 | 0.7173 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 705 | 656 | | 2086 | 7084 | 755.3 | 409.67 | 4.68 | 2.47 | 169 | 264 | 426 | 649 | 862 | 982 | 1060 | 1141 | 1240 | 0.0841 | 596 | 0.902 | 85.38 | 22.85 | 2 | 0.1112 | 232 | 0.0008 | 88.53 | 7.287 | 0.1150 | 738249.0 | 798000000 | 907000000000 | 1.07E+15 | 0.3090 | 0.2823 | 0.0000 | 0.0000 | 0.0167 | 0.0013 | 0.0167 | 0.0013 | 0.0733 | 0.0088 | 0.3067 | 0.1107 | 0.2867 | 0.1723 | 0.1300 | 0.1233 | 0.1300 | 0.1849 | 0.0400 | 0.3975 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0264 | 0.0280 | 0.0380 | 0.0350 | 0.0233 | 0.0224 | 0.0396 | 0.0378 | 0.8712 | 0.8768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0016 | 0.0030 | 0.0174 | 0.0324 | 0.0757 | 0.0576 | 0.1372 | 0.0536 | 0.0931 | 0.0890 | 0.1483 | 0.7634 | 0.5268 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0328 | 0.0345 | 0.0276 | 0.0405 | 0.8638 | 2 | 3 | 3 | 4 | 4 | 5 | 6 | 7 | 8 | 0.0353 | 0.22 | 0.723 | 0.2177 | 28.0 | 197.373 | 1573.42 | 13861.8 | 0.4480 | 0.1854 | 0.0919 | 0.0083 | 0.1989 | 0.0206 | 0.2527 | 0.0511 | 0.2301 | 0.0975 | 0.1382 | 0.1832 | 0.0656 | 0.2464 | 0.0204 | 0.2343 | 0.0022 | 0.1254 | 0.0000 | 0.0331 | 0.0082 | 0.0009 | 0.0316 | 0.0026 | 0.0687 | 0.0139 | 0.0919 | 0.0357 | 0.1178 | 0.0764 | 0.1357 | 0.1283 | 0.1428 | 0.1664 | 0.1753 | 0.2158 | 0.2280 | 0.3601 | 0.0631 | 0.0852 | 0.0954 | 0.1085 | 0.0927 | 0.1085 | 0.0907 | 0.1143 | 0.1286 | 0.1214 | 0.1226 | 0.1375 | 0.1302 | 0.1336 | 0.1434 | 0.0943 | 0.1334 | 0.0968 | 0.0278 | 0.0633 | 0.1001 | 0.0986 | 0.1143 | 0.1134 | 0.1331 | 0.1597 | 0.1898 | ||
| BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 355 | 746 | | 5178 | 14618 | 327.7 | 65.14 | 129.72 | 168.91 | 250 | 272 | 289 | 304 | 321 | 339 | 359 | 383 | 416 | 0.0483 | 706 | 1.223 | 132.20 | 48.33 | 1 | 0.0624 | 323 | 0.0006 | 79.47 | 7.577 | 0.1347 | 111643.0 | 39500000 | 14500000000 | 5500000000000 | 0.4016 | 0.2477 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0000 | 0.0124 | 0.0010 | 0.0615 | 0.0141 | 0.1154 | 0.0278 | 0.1391 | 0.0377 | 0.1708 | 0.0498 | 0.4976 | 0.8695 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0009 | 0.0000 | 0.0048 | 0.0006 | 0.0275 | 0.0103 | 0.0562 | 0.0177 | 0.0558 | 0.0168 | 0.0767 | 0.0242 | 0.7779 | 0.9305 | 0.0000 | 0.0057 | 0.0082 | 0.0341 | 0.0411 | 0.0625 | 0.0799 | 0.1591 | 0.1246 | 0.1932 | 0.1669 | 0.1648 | 0.1269 | 0.1193 | 0.1504 | 0.1307 | 0.3020 | 0.1307 | 0.0025 | 0.0038 | 0.0046 | 0.0302 | 0.0772 | 0.1234 | 0.1083 | 0.1318 | 0.5183 | 11 | 13 | 15 | 20 | 32 | 75 | 158 | 264 | 389 | 0.0486 | 32.17 | 5.262 | 0.4801 | 45355.6 | 21000000 | 11400000000 | 6870000000000 | 0.5030 | 0.1599 | 0.1206 | 0.0006 | 0.3330 | 0.0356 | 0.3146 | 0.2808 | 0.1079 | 0.2475 | 0.0769 | 0.1991 | 0.0321 | 0.1068 | 0.0115 | 0.0595 | 0.0023 | 0.0473 | 0.0011 | 0.0228 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0117 | 0.0095 | 0.0635 | 0.0521 | 0.0928 | 0.0937 | 0.0628 | 0.0577 | 0.1074 | 0.0968 | 0.6595 | 0.6891 | 0.0007 | 0.0007 | 0.0007 | 0.0015 | 0.0029 | 0.0020 | 0.0167 | 0.0162 | 0.0625 | 0.0729 | 0.1186 | 0.1226 | 0.0783 | 0.0896 | 0.1208 | 0.1300 | 0.5988 | 0.5646 | 0.0000 | 0.0002 | 0.0037 | 0.0165 | 0.0591 | 0.1021 | 0.0779 | 0.1118 | 0.6285 |