High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 923 | 749 | | 18485 | 19144 | 337.4 | 48.91 | 148.53 | 162.19 | 268 | 300 | 318 | 331 | 344 | 355 | 367 | 380 | 396 | 0.0705 | 1349 | 1.142 | 100.72 | 39.20 | 2 | 0.0147 | 271 | 0.0025 | 9.90 | 6.327 | 0.3429 | 116234.0 | 40800000 | 14500000000 | 5230000000000 | 0.4218 | 0.2181 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0027 | 0.0001 | 0.0083 | 0.0008 | 0.0174 | 0.0071 | 0.0285 | 0.0145 | 0.0316 | 0.0074 | 0.0551 | 0.0119 | 0.8546 | 0.9581 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0001 | 0.0022 | 0.0008 | 0.0085 | 0.0071 | 0.0136 | 0.0145 | 0.0122 | 0.0074 | 0.0186 | 0.0119 | 0.9443 | 0.9581 | 0.0326 | 0.0000 | 0.0692 | 0.0000 | 0.0794 | 0.0000 | 0.1090 | 0.0000 | 0.1517 | 0.0000 | 0.1415 | 0.0000 | 0.1395 | 0.0000 | 0.1446 | 0.0000 | 0.1324 | 0.0000 | 0.0028 | 0.0050 | 0.0091 | 0.0138 | 0.0293 | 0.0412 | 0.0457 | 0.0737 | 0.7793 | 23 | 31 | 42 | 57 | 77 | 109 | 167 | 256 | 387 | 0.0183 | 13.36 | 5.441 | 0.5104 | 48364.8 | 22700000 | 12800000000 | 8140000000000 | 0.3890 | 0.2609 | 0.0233 | 0.0013 | 0.0952 | 0.0085 | 0.1700 | 0.0530 | 0.1578 | 0.1011 | 0.1966 | 0.1512 | 0.1445 | 0.1702 | 0.0908 | 0.1386 | 0.0714 | 0.1404 | 0.0504 | 0.2358 | 0.0001 | 0.0003 | 0.0008 | 0.0009 | 0.0026 | 0.0044 | 0.0128 | 0.0124 | 0.0492 | 0.0417 | 0.0708 | 0.0661 | 0.0547 | 0.0448 | 0.0827 | 0.0706 | 0.7262 | 0.7587 | 0.0007 | 0.0006 | 0.0009 | 0.0017 | 0.0035 | 0.0058 | 0.0196 | 0.0235 | 0.0581 | 0.0707 | 0.0989 | 0.0946 | 0.0629 | 0.0773 | 0.0941 | 0.1006 | 0.6612 | 0.6252 | 0.0000 | 0.0010 | 0.0043 | 0.0159 | 0.0522 | 0.0864 | 0.0570 | 0.0870 | 0.6963 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 937 | 792 | | 9123 | 21746 | 335.0 | 60.34 | 75.58 | 106.02 | 251 | 283 | 304 | 322 | 338 | 352 | 368 | 385 | 407 | 0.0469 | 1020 | 1.203 | 88.96 | 31.32 | 2 | 0.0240 | 219 | 0.0031 | 5.79 | 6.087 | 0.3990 | 115860.0 | 41200000 | 15100000000 | 5640000000000 | 0.3775 | 0.2592 | 0.0006 | 0.0000 | 0.0019 | 0.0001 | 0.0030 | 0.0007 | 0.0099 | 0.0012 | 0.0231 | 0.0099 | 0.0367 | 0.0248 | 0.0410 | 0.0160 | 0.0611 | 0.0234 | 0.8226 | 0.9239 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0010 | 0.0003 | 0.0037 | 0.0008 | 0.0116 | 0.0086 | 0.0156 | 0.0195 | 0.0156 | 0.0089 | 0.0230 | 0.0132 | 0.9290 | 0.9487 | 0.0127 | 0.0397 | 0.0136 | 0.0397 | 0.0363 | 0.1429 | 0.0417 | 0.1190 | 0.0644 | 0.1587 | 0.0816 | 0.1905 | 0.0743 | 0.0635 | 0.0988 | 0.0952 | 0.5766 | 0.1508 | 0.0021 | 0.0040 | 0.0109 | 0.0129 | 0.0253 | 0.0322 | 0.0430 | 0.0670 | 0.8026 | 6 | 7 | 9 | 13 | 26 | 46 | 79 | 134 | 219 | 0.0597 | 7.19 | 4.039 | 0.5263 | 16952.4 | 5760000 | 2510000000 | 1300000000000 | 0.3182 | 0.3239 | 0.0564 | 0.0038 | 0.1472 | 0.0263 | 0.2620 | 0.0928 | 0.1675 | 0.1276 | 0.1368 | 0.1702 | 0.0969 | 0.1688 | 0.0595 | 0.1401 | 0.0485 | 0.1159 | 0.0252 | 0.1545 | 0.0001 | 0.0005 | 0.0012 | 0.0006 | 0.0032 | 0.0031 | 0.0151 | 0.0112 | 0.0474 | 0.0451 | 0.0827 | 0.0582 | 0.0582 | 0.0542 | 0.0838 | 0.0756 | 0.7083 | 0.7517 | 0.0012 | 0.0002 | 0.0012 | 0.0019 | 0.0027 | 0.0043 | 0.0211 | 0.0249 | 0.0642 | 0.0784 | 0.1127 | 0.1071 | 0.0701 | 0.0779 | 0.0991 | 0.1155 | 0.6278 | 0.5898 | 0.0006 | 0.0010 | 0.0024 | 0.0164 | 0.0621 | 0.0942 | 0.0691 | 0.0956 | 0.6587 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 309 | 287 | | 6693 | 13038 | 535.8 | 126.02 | 220.15 | 377.39 | 361 | 403 | 454 | 495 | 535 | 584 | 628 | 661 | 696 | 0.0639 | 833 | 0.910 | 75.03 | 22.56 | 1 | 0.0288 | 193 | 0.0006 | 30.06 | 7.569 | 0.2086 | 303013.0 | 179000000 | 110000000000 | 69800000000000 | 0.3886 | 0.2484 | 0.0015 | 0.0000 | 0.0045 | 0.0003 | 0.0063 | 0.0009 | 0.0218 | 0.0046 | 0.0499 | 0.0146 | 0.0646 | 0.0195 | 0.0738 | 0.0255 | 0.0999 | 0.0304 | 0.6777 | 0.9041 | 0.0002 | 0.0000 | 0.0006 | 0.0002 | 0.0000 | 0.0006 | 0.0040 | 0.0031 | 0.0151 | 0.0121 | 0.0173 | 0.0144 | 0.0213 | 0.0153 | 0.0279 | 0.0185 | 0.9136 | 0.9358 | 0.0000 | 0.0057 | 0.0066 | 0.0230 | 0.0119 | 0.0575 | 0.0328 | 0.0862 | 0.0519 | 0.1552 | 0.0781 | 0.1092 | 0.0972 | 0.1322 | 0.1151 | 0.1379 | 0.6064 | 0.2931 | 0.0003 | 0.0012 | 0.0018 | 0.0075 | 0.0221 | 0.0392 | 0.0374 | 0.0502 | 0.8404 | 9 | 11 | 13 | 16 | 29 | 82 | 190 | 352 | 702 | 0.1372 | 64.08 | 4.831 | 0.5651 | 190878.0 | 238000000 | 347000000000 | 556000000000000 | 0.2850 | 0.3373 | 0.0407 | 0.0012 | 0.1423 | 0.0098 | 0.1842 | 0.0952 | 0.1160 | 0.1173 | 0.1651 | 0.1419 | 0.1471 | 0.1751 | 0.0969 | 0.1204 | 0.0682 | 0.1106 | 0.0395 | 0.2285 | 0.0000 | 0.0000 | 0.0010 | 0.0002 | 0.0030 | 0.0007 | 0.0114 | 0.0099 | 0.0445 | 0.0399 | 0.0736 | 0.0527 | 0.0521 | 0.0432 | 0.0692 | 0.0647 | 0.7453 | 0.7886 | 0.0012 | 0.0003 | 0.0000 | 0.0010 | 0.0028 | 0.0059 | 0.0177 | 0.0200 | 0.0570 | 0.0596 | 0.0906 | 0.0950 | 0.0548 | 0.0665 | 0.0878 | 0.0871 | 0.6880 | 0.6646 | 0.0006 | 0.0008 | 0.0019 | 0.0171 | 0.0521 | 0.0803 | 0.0576 | 0.0745 | 0.7151 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 305 | 753 | | 14531 | 31502 | 446.4 | 61.03 | 117.13 | 162.48 | 365 | 402 | 424 | 439 | 452 | 464 | 476 | 491 | 515 | 0.0488 | 1538 | 0.844 | 110.02 | 27.80 | 4 | 0.0189 | 274 | 0.0017 | 18.96 | 6.823 | 0.2707 | 202963.0 | 93800000 | 44000000000 | 21000000000000 | 0.4307 | 0.2135 | 0.0003 | 0.0001 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0036 | 0.0001 | 0.0149 | 0.0077 | 0.0284 | 0.0166 | 0.0253 | 0.0080 | 0.0383 | 0.0128 | 0.8882 | 0.9547 | 0.0001 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0001 | 0.0098 | 0.0077 | 0.0186 | 0.0166 | 0.0149 | 0.0080 | 0.0188 | 0.0117 | 0.9360 | 0.9558 | 0.0148 | 1.0000 | 0.0239 | 0.0000 | 0.0091 | 0.0000 | 0.0262 | 0.0000 | 0.0809 | 0.0000 | 0.0945 | 0.0000 | 0.0809 | 0.0000 | 0.1173 | 0.0000 | 0.5524 | 0.0000 | 0.0022 | 0.0070 | 0.0123 | 0.0187 | 0.0346 | 0.0523 | 0.0642 | 0.0921 | 0.7167 | 13 | 16 | 21 | 33 | 52 | 79 | 118 | 180 | 305 | 0.0400 | 19.55 | 4.937 | 0.5597 | 40119.5 | 22800000 | 16800000000 | 14600000000000 | 0.4801 | 0.1897 | 0.0180 | 0.0019 | 0.0684 | 0.0102 | 0.1417 | 0.0304 | 0.1389 | 0.0605 | 0.1660 | 0.1385 | 0.1648 | 0.1775 | 0.1107 | 0.1263 | 0.1041 | 0.1394 | 0.0873 | 0.3154 | 0.0012 | 0.0003 | 0.0022 | 0.0020 | 0.0034 | 0.0030 | 0.0115 | 0.0124 | 0.0463 | 0.0387 | 0.0745 | 0.0614 | 0.0495 | 0.0472 | 0.0766 | 0.0656 | 0.7348 | 0.7694 | 0.0005 | 0.0007 | 0.0024 | 0.0020 | 0.0066 | 0.0068 | 0.0187 | 0.0217 | 0.0585 | 0.0622 | 0.0953 | 0.1084 | 0.0633 | 0.0699 | 0.0954 | 0.0979 | 0.6595 | 0.6304 | 0.0004 | 0.0017 | 0.0044 | 0.0151 | 0.0498 | 0.0888 | 0.0599 | 0.0831 | 0.6968 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 708 | 397 | | 15447 | 27394 | 562.4 | 113.78 | 118.30 | 212.73 | 394 | 458 | 507 | 542 | 576 | 606 | 636 | 667 | 703 | 0.0495 | 1356 | 0.896 | 108.19 | 30.00 | 3 | 0.0188 | 291 | 0.0006 | 29.72 | 7.605 | 0.2191 | 329218.0 | 199000000 | 124000000000 | 78600000000000 | 0.3988 | 0.2308 | 0.0014 | 0.0000 | 0.0019 | 0.0001 | 0.0040 | 0.0004 | 0.0105 | 0.0011 | 0.0269 | 0.0087 | 0.0473 | 0.0169 | 0.0485 | 0.0102 | 0.0672 | 0.0157 | 0.7922 | 0.9469 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0001 | 0.0023 | 0.0010 | 0.0107 | 0.0080 | 0.0188 | 0.0166 | 0.0160 | 0.0091 | 0.0204 | 0.0143 | 0.9310 | 0.9510 | 0.0029 | 0.0000 | 0.0095 | 0.0179 | 0.0147 | 0.0536 | 0.0297 | 0.1607 | 0.0612 | 0.1250 | 0.0718 | 0.1071 | 0.0872 | 0.2500 | 0.1213 | 0.1071 | 0.6015 | 0.1786 | 0.0008 | 0.0010 | 0.0032 | 0.0069 | 0.0226 | 0.0401 | 0.0411 | 0.0534 | 0.8309 | 7 | 9 | 10 | 11 | 12 | 15 | 40 | 206 | 467 | 0.3132 | 20.18 | 3.462 | 0.7115 | 59247.2 | 38200000 | 27600000000 | 21600000000000 | 0.5023 | 0.1444 | 0.0436 | 0.0036 | 0.1336 | 0.0128 | 0.2377 | 0.1026 | 0.1744 | 0.1354 | 0.1547 | 0.1810 | 0.1069 | 0.1882 | 0.0675 | 0.1055 | 0.0520 | 0.1119 | 0.0295 | 0.1589 | 0.0000 | 0.0003 | 0.0003 | 0.0004 | 0.0010 | 0.0004 | 0.0058 | 0.0038 | 0.0203 | 0.0189 | 0.0418 | 0.0353 | 0.0301 | 0.0220 | 0.0517 | 0.0418 | 0.8491 | 0.8771 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0058 | 0.0079 | 0.0263 | 0.0302 | 0.0558 | 0.0631 | 0.0452 | 0.0492 | 0.0622 | 0.0705 | 0.8037 | 0.7782 | 0.0000 | 0.0000 | 0.0006 | 0.0049 | 0.0263 | 0.0486 | 0.0405 | 0.0571 | 0.8221 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 900 | 171 | | 3930 | 11298 | 497.7 | 103.96 | 94.40 | 173.19 | 316 | 409 | 476 | 500 | 521 | 540 | 560 | 583 | 613 | 0.0641 | 724 | 0.847 | 112.54 | 33.02 | 4 | 0.0832 | 327 | 0.0011 | 32.58 | 7.096 | 0.2211 | 258499.0 | 139000000 | 76000000000 | 42400000000000 | 0.3874 | 0.2511 | 0.0008 | 0.0003 | 0.0015 | 0.0000 | 0.0057 | 0.0000 | 0.0069 | 0.0008 | 0.0413 | 0.0186 | 0.0462 | 0.0251 | 0.0569 | 0.0178 | 0.0810 | 0.0276 | 0.7597 | 0.9099 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0008 | 0.0197 | 0.0186 | 0.0188 | 0.0251 | 0.0172 | 0.0178 | 0.0260 | 0.0276 | 0.9179 | 0.9099 | 0.0052 | 0.0000 | 0.0140 | 0.0000 | 0.0315 | 0.0000 | 0.0542 | 0.0000 | 0.0717 | 0.0000 | 0.0944 | 0.0000 | 0.1119 | 0.0000 | 0.1556 | 0.0000 | 0.4615 | 0.0000 | 0.0012 | 0.0042 | 0.0037 | 0.0108 | 0.0279 | 0.0396 | 0.0500 | 0.0629 | 0.7997 | 6 | 7 | 9 | 10 | 14 | 24 | 52 | 125 | 339 | 0.1266 | 21.37 | 4.235 | 0.6154 | 38902.8 | 22700000 | 15400000000 | 11500000000000 | 0.5106 | 0.1373 | 0.0416 | 0.0018 | 0.1323 | 0.0210 | 0.2420 | 0.0602 | 0.1739 | 0.1267 | 0.1815 | 0.2124 | 0.1361 | 0.2042 | 0.0586 | 0.1258 | 0.0265 | 0.1167 | 0.0076 | 0.1313 | 0.0000 | 0.0003 | 0.0003 | 0.0009 | 0.0031 | 0.0015 | 0.0097 | 0.0106 | 0.0497 | 0.0439 | 0.0660 | 0.0569 | 0.0453 | 0.0375 | 0.0729 | 0.0623 | 0.7530 | 0.7860 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0013 | 0.0018 | 0.0139 | 0.0172 | 0.0499 | 0.0548 | 0.0820 | 0.0743 | 0.0465 | 0.0535 | 0.0714 | 0.0729 | 0.7342 | 0.7254 | 0.0008 | 0.0000 | 0.0015 | 0.0131 | 0.0528 | 0.0670 | 0.0466 | 0.0751 | 0.7432 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1189 | 733 | | 6368 | 8540 | 460.5 | 95.33 | 276.86 | 365.75 | 341 | 370 | 398 | 426 | 449 | 474 | 509 | 550 | 597 | 0.0848 | 724 | 0.776 | 177.72 | 41.62 | 1 | 0.0785 | 500 | 0.0009 | 23.98 | 7.222 | 0.2306 | 221183.0 | 111000000 | 57400000000 | 30900000000000 | 0.4039 | 0.2350 | 0.0005 | 0.0000 | 0.0020 | 0.0003 | 0.0059 | 0.0005 | 0.0136 | 0.0018 | 0.0358 | 0.0143 | 0.0491 | 0.0278 | 0.0573 | 0.0203 | 0.0893 | 0.0345 | 0.7465 | 0.9005 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0021 | 0.0000 | 0.0072 | 0.0005 | 0.0145 | 0.0099 | 0.0191 | 0.0206 | 0.0217 | 0.0093 | 0.0320 | 0.0179 | 0.9023 | 0.9419 | 0.0074 | 0.0186 | 0.0017 | 0.0372 | 0.0124 | 0.0558 | 0.0314 | 0.0884 | 0.0553 | 0.1023 | 0.0677 | 0.1395 | 0.0619 | 0.1302 | 0.0958 | 0.1535 | 0.6664 | 0.2744 | 0.0003 | 0.0024 | 0.0069 | 0.0180 | 0.0340 | 0.0506 | 0.0544 | 0.0634 | 0.7698 | 9 | 12 | 16 | 59 | 118 | 196 | 330 | 523 | 797 | 0.0654 | 101.98 | 5.746 | 0.4428 | 210404.0 | 226000000 | 301000000000 | 467000000000000 | 0.4431 | 0.2080 | 0.0250 | 0.0028 | 0.1591 | 0.0106 | 0.2872 | 0.0700 | 0.1944 | 0.1272 | 0.1399 | 0.1965 | 0.1046 | 0.2367 | 0.0442 | 0.1357 | 0.0339 | 0.1074 | 0.0118 | 0.1131 | 0.0000 | 0.0000 | 0.0006 | 0.0011 | 0.0028 | 0.0030 | 0.0130 | 0.0116 | 0.0551 | 0.0462 | 0.0740 | 0.0648 | 0.0688 | 0.0562 | 0.0988 | 0.0759 | 0.6869 | 0.7413 | 0.0008 | 0.0004 | 0.0016 | 0.0026 | 0.0035 | 0.0044 | 0.0208 | 0.0219 | 0.0631 | 0.0804 | 0.1145 | 0.1307 | 0.0922 | 0.0979 | 0.1196 | 0.1281 | 0.5839 | 0.5337 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0601 | 0.0984 | 0.0766 | 0.1131 | 0.6325 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 655 | 519 | | 12431 | 24620 | 390.0 | 70.08 | 73.02 | 145.52 | 287 | 322 | 350 | 376 | 398 | 418 | 437 | 454 | 476 | 0.0531 | 1307 | 0.717 | 116.71 | 35.11 | 3 | 0.0323 | 401 | 0.0014 | 13.24 | 6.814 | 0.3028 | 157023.0 | 65000000 | 27500000000 | 11900000000000 | 0.4378 | 0.1981 | 0.0007 | 0.0000 | 0.0029 | 0.0000 | 0.0055 | 0.0000 | 0.0115 | 0.0009 | 0.0276 | 0.0098 | 0.0447 | 0.0175 | 0.0492 | 0.0111 | 0.0732 | 0.0171 | 0.7847 | 0.9436 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0000 | 0.0037 | 0.0009 | 0.0122 | 0.0098 | 0.0195 | 0.0175 | 0.0178 | 0.0105 | 0.0271 | 0.0152 | 0.9168 | 0.9461 | 0.0102 | 1.0000 | 0.0215 | 0.0000 | 0.0269 | 0.0000 | 0.0449 | 0.0000 | 0.0682 | 0.0000 | 0.0922 | 0.0000 | 0.0999 | 0.0000 | 0.1191 | 0.0000 | 0.5171 | 0.0000 | 0.0007 | 0.0036 | 0.0042 | 0.0104 | 0.0227 | 0.0348 | 0.0407 | 0.0547 | 0.8282 | 8 | 10 | 11 | 13 | 15 | 20 | 33 | 82 | 218 | 0.1379 | 2.58 | 2.741 | 0.6004 | 26508.4 | 16200000 | 12600000000 | 11400000000000 | 0.6289 | 0.0769 | 0.0413 | 0.0027 | 0.1013 | 0.0182 | 0.1888 | 0.0633 | 0.1750 | 0.0919 | 0.1721 | 0.1461 | 0.1327 | 0.1875 | 0.1013 | 0.1379 | 0.0560 | 0.1347 | 0.0315 | 0.2176 | 0.0002 | 0.0005 | 0.0007 | 0.0006 | 0.0016 | 0.0015 | 0.0123 | 0.0101 | 0.0446 | 0.0428 | 0.0768 | 0.0683 | 0.0519 | 0.0466 | 0.0718 | 0.0703 | 0.7402 | 0.7592 | 0.0004 | 0.0009 | 0.0008 | 0.0018 | 0.0023 | 0.0018 | 0.0159 | 0.0140 | 0.0529 | 0.0605 | 0.0898 | 0.0918 | 0.0567 | 0.0628 | 0.0814 | 0.0868 | 0.6997 | 0.6794 | 0.0004 | 0.0000 | 0.0015 | 0.0114 | 0.0529 | 0.0806 | 0.0550 | 0.0825 | 0.7157 |
| SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1207 | 207 | | 6980 | 19624 | 335.7 | 74.32 | 299.24 | 411.18 | 218 | 282 | 315 | 337 | 355 | 370 | 382 | 395 | 412 | 0.0495 | 972 | 0.878 | 105.01 | 22.67 | 2 | 0.0338 | 236 | 0.0016 | 18.87 | 6.802 | 0.2595 | 118201.0 | 43000000 | 16000000000 | 6030000000000 | 0.3992 | 0.2312 | 0.0008 | 0.0000 | 0.0019 | 0.0000 | 0.0057 | 0.0000 | 0.0151 | 0.0005 | 0.0362 | 0.0109 | 0.0496 | 0.0198 | 0.0603 | 0.0114 | 0.1042 | 0.0181 | 0.7262 | 0.9392 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0033 | 0.0005 | 0.0117 | 0.0106 | 0.0200 | 0.0197 | 0.0164 | 0.0105 | 0.0219 | 0.0154 | 0.9264 | 0.9434 | 0.0234 | 0.1429 | 0.0263 | 0.0000 | 0.0536 | 0.4286 | 0.0623 | 0.2857 | 0.0837 | 0.1429 | 0.1003 | 0.0000 | 0.1120 | 0.0000 | 0.1324 | 0.0000 | 0.4060 | 0.0000 | 0.0007 | 0.0016 | 0.0028 | 0.0094 | 0.0211 | 0.0392 | 0.0446 | 0.0634 | 0.8170 | 12 | 16 | 20 | 28 | 78 | 180 | 350 | 599 | 943 | 0.0721 | 64.70 | 5.520 | 0.4930 | 258610.0 | 294000000 | 385000000000 | 559000000000000 | 0.4020 | 0.2305 | 0.0543 | 0.0023 | 0.2124 | 0.0098 | 0.3077 | 0.0976 | 0.1647 | 0.1574 | 0.1179 | 0.2237 | 0.0828 | 0.2003 | 0.0326 | 0.1140 | 0.0217 | 0.0910 | 0.0059 | 0.1039 | 0.0003 | 0.0000 | 0.0001 | 0.0001 | 0.0013 | 0.0004 | 0.0073 | 0.0059 | 0.0473 | 0.0415 | 0.0872 | 0.0708 | 0.0574 | 0.0514 | 0.0844 | 0.0737 | 0.7147 | 0.7561 | 0.0003 | 0.0002 | 0.0014 | 0.0008 | 0.0026 | 0.0025 | 0.0115 | 0.0140 | 0.0574 | 0.0661 | 0.1058 | 0.1190 | 0.0739 | 0.0814 | 0.1015 | 0.1092 | 0.6456 | 0.6068 | 0.0002 | 0.0005 | 0.0011 | 0.0070 | 0.0580 | 0.0920 | 0.0640 | 0.0926 | 0.6846 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1201 | 147 | | 25401 | 21792 | 80.3 | 36.47 | 7.79 | 3.16 | 47 | 51 | 55 | 60 | 67 | 79 | 95 | 111 | 130 | 0.0646 | 1407 | 0.643 | 109.48 | 22.02 | 3 | 0.0122 | 311 | 0.0238 | 1.54 | 4.339 | 0.6433 | 7784.7 | 930349 | 141000000 | 27400000000 | 0.3746 | 0.2574 | 0.0183 | 0.0041 | 0.0285 | 0.0101 | 0.0332 | 0.0165 | 0.0445 | 0.0216 | 0.0579 | 0.0307 | 0.0760 | 0.0454 | 0.0991 | 0.0645 | 0.1547 | 0.1011 | 0.4878 | 0.7059 | 0.0063 | 0.0025 | 0.0088 | 0.0051 | 0.0101 | 0.0093 | 0.0128 | 0.0127 | 0.0158 | 0.0171 | 0.0202 | 0.0254 | 0.0263 | 0.0353 | 0.0450 | 0.0545 | 0.8547 | 0.8381 | 0.0029 | 0.0096 | 0.0051 | 0.0076 | 0.0087 | 0.0135 | 0.0154 | 0.0237 | 0.0181 | 0.0317 | 0.0252 | 0.0416 | 0.0356 | 0.0590 | 0.0614 | 0.0833 | 0.8277 | 0.7300 | 0.0039 | 0.0045 | 0.0066 | 0.0106 | 0.0121 | 0.0194 | 0.0250 | 0.0402 | 0.8777 | 4 | 5 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.3288 | 0.54 | 1.489 | 0.7679 | 70.7 | 710.738 | 7758.34 | 90867.1 | 0.5651 | 0.1468 | 0.0276 | 0.0002 | 0.1012 | 0.0027 | 0.1830 | 0.0162 | 0.2395 | 0.0448 | 0.2232 | 0.1065 | 0.1440 | 0.1983 | 0.0622 | 0.2724 | 0.0175 | 0.2494 | 0.0018 | 0.1095 | 0.0011 | 0.0001 | 0.0095 | 0.0007 | 0.0313 | 0.0047 | 0.0743 | 0.0148 | 0.1392 | 0.0405 | 0.2209 | 0.1002 | 0.2544 | 0.1989 | 0.1985 | 0.3291 | 0.0707 | 0.3109 | 0.0837 | 0.3817 | 0.2220 | 0.3524 | 0.2715 | 0.1695 | 0.2102 | 0.0699 | 0.1317 | 0.0232 | 0.0547 | 0.0028 | 0.0218 | 0.0004 | 0.0035 | 0.0000 | 0.0010 | 0.0000 | 0.0061 | 0.0422 | 0.1149 | 0.1974 | 0.2403 | 0.2128 | 0.1308 | 0.0484 | 0.0072 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 889 | 579 | | 5344 | 14258 | 479.3 | 73.36 | 59.66 | 126.81 | 384 | 417 | 439 | 460 | 479 | 496 | 514 | 540 | 582 | 0.0560 | 799 | 1.214 | 72.84 | 31.83 | 1 | 0.0378 | 202 | 0.0020 | 11.27 | 6.511 | 0.3208 | 235079.0 | 118000000 | 60300000000 | 31500000000000 | 0.4020 | 0.2453 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0066 | 0.0002 | 0.0216 | 0.0122 | 0.0337 | 0.0213 | 0.0309 | 0.0112 | 0.0475 | 0.0182 | 0.8575 | 0.9369 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0021 | 0.0002 | 0.0127 | 0.0122 | 0.0206 | 0.0213 | 0.0145 | 0.0112 | 0.0247 | 0.0167 | 0.9252 | 0.9384 | 0.0000 | 1.0000 | 0.0232 | 0.0000 | 0.0066 | 0.0000 | 0.0381 | 0.0000 | 0.0381 | 0.0000 | 0.0614 | 0.0000 | 0.0779 | 0.0000 | 0.0962 | 0.0000 | 0.6584 | 0.0000 | 0.0019 | 0.0026 | 0.0071 | 0.0160 | 0.0360 | 0.0527 | 0.0605 | 0.0854 | 0.7379 | 6 | 7 | 8 | 9 | 11 | 14 | 23 | 58 | 184 | 0.1961 | 6.16 | 3.029 | 0.6633 | 19637.6 | 11000000 | 8130000000 | 7350000000000 | 0.5394 | 0.1197 | 0.0721 | 0.0088 | 0.1081 | 0.0431 | 0.2450 | 0.1186 | 0.1766 | 0.0958 | 0.1315 | 0.1511 | 0.1045 | 0.1722 | 0.0829 | 0.1178 | 0.0541 | 0.1283 | 0.0252 | 0.1643 | 0.0010 | 0.0000 | 0.0013 | 0.0011 | 0.0048 | 0.0056 | 0.0166 | 0.0189 | 0.0507 | 0.0498 | 0.0842 | 0.0715 | 0.0555 | 0.0540 | 0.0778 | 0.0791 | 0.7083 | 0.7200 | 0.0008 | 0.0004 | 0.0027 | 0.0029 | 0.0023 | 0.0037 | 0.0139 | 0.0166 | 0.0616 | 0.0605 | 0.0953 | 0.0957 | 0.0581 | 0.0609 | 0.0817 | 0.0787 | 0.6836 | 0.6807 | 0.0007 | 0.0021 | 0.0021 | 0.0220 | 0.0535 | 0.0839 | 0.0676 | 0.0740 | 0.6941 | ||
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 980 | 154 | | 9107 | 15265 | 478.7 | 85.92 | 198.56 | 276.33 | 358 | 401 | 437 | 463 | 485 | 506 | 527 | 552 | 588 | 0.0735 | 1122 | 0.982 | 84.40 | 29.43 | 4 | 0.0254 | 231 | 0.0010 | 22.23 | 7.221 | 0.2396 | 236580.0 | 120000000 | 62600000000 | 33300000000000 | 0.4434 | 0.2060 | 0.0008 | 0.0000 | 0.0015 | 0.0000 | 0.0041 | 0.0001 | 0.0113 | 0.0006 | 0.0270 | 0.0119 | 0.0415 | 0.0194 | 0.0463 | 0.0139 | 0.0694 | 0.0222 | 0.7980 | 0.9319 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0012 | 0.0000 | 0.0040 | 0.0006 | 0.0131 | 0.0117 | 0.0209 | 0.0179 | 0.0208 | 0.0114 | 0.0297 | 0.0180 | 0.9101 | 0.9405 | 0.0083 | 0.0294 | 0.0173 | 0.0588 | 0.0273 | 0.0882 | 0.0380 | 0.2059 | 0.0512 | 0.2353 | 0.0760 | 0.1471 | 0.0950 | 0.1471 | 0.1230 | 0.0588 | 0.5640 | 0.0294 | 0.0010 | 0.0031 | 0.0072 | 0.0149 | 0.0256 | 0.0345 | 0.0450 | 0.0565 | 0.8122 | 11 | 14 | 19 | 34 | 73 | 133 | 224 | 349 | 565 | 0.0491 | 47.73 | 5.568 | 0.4783 | 115779.0 | 101000000 | 112000000000 | 147000000000000 | 0.3844 | 0.2395 | 0.0410 | 0.0015 | 0.1640 | 0.0173 | 0.2243 | 0.0857 | 0.1640 | 0.1357 | 0.1446 | 0.1765 | 0.1106 | 0.1922 | 0.0789 | 0.1361 | 0.0472 | 0.1023 | 0.0255 | 0.1526 | 0.0004 | 0.0003 | 0.0011 | 0.0014 | 0.0023 | 0.0048 | 0.0151 | 0.0114 | 0.0519 | 0.0457 | 0.0774 | 0.0628 | 0.0614 | 0.0517 | 0.0854 | 0.0750 | 0.7052 | 0.7469 | 0.0002 | 0.0005 | 0.0018 | 0.0031 | 0.0067 | 0.0089 | 0.0220 | 0.0270 | 0.0687 | 0.0786 | 0.1061 | 0.1226 | 0.0859 | 0.0881 | 0.1079 | 0.1098 | 0.6006 | 0.5613 | 0.0004 | 0.0012 | 0.0052 | 0.0181 | 0.0596 | 0.0890 | 0.0721 | 0.1031 | 0.6512 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 673 | 661 | | 8356 | 21692 | 629.4 | 88.97 | 157.77 | 200.04 | 505 | 558 | 588 | 612 | 637 | 660 | 678 | 703 | 736 | 0.0423 | 917 | 1.088 | 108.30 | 37.05 | 1 | 0.0333 | 278 | 0.0009 | 30.54 | 7.337 | 0.2196 | 404042.0 | 264000000 | 175000000000 | 118000000000000 | 0.4222 | 0.2219 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0007 | 0.0000 | 0.0036 | 0.0002 | 0.0168 | 0.0091 | 0.0339 | 0.0170 | 0.0309 | 0.0087 | 0.0431 | 0.0141 | 0.8703 | 0.9508 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0017 | 0.0002 | 0.0097 | 0.0091 | 0.0211 | 0.0170 | 0.0174 | 0.0087 | 0.0212 | 0.0141 | 0.9286 | 0.9508 | 0.0052 | 0.0000 | 0.0087 | 0.0000 | 0.0280 | 0.0000 | 0.0332 | 0.0000 | 0.0769 | 0.0000 | 0.1206 | 0.0000 | 0.0962 | 0.0000 | 0.1521 | 0.0000 | 0.4790 | 0.0000 | 0.0011 | 0.0031 | 0.0058 | 0.0105 | 0.0285 | 0.0524 | 0.0515 | 0.0731 | 0.7740 | 10 | 13 | 19 | 33 | 63 | 113 | 189 | 289 | 461 | 0.0633 | 29.43 | 5.277 | 0.5302 | 64906.9 | 36700000 | 24600000000 | 18400000000000 | 0.4278 | 0.2001 | 0.0270 | 0.0020 | 0.1224 | 0.0151 | 0.2282 | 0.0660 | 0.1787 | 0.1115 | 0.1483 | 0.1596 | 0.1201 | 0.2156 | 0.0684 | 0.1388 | 0.0615 | 0.1073 | 0.0454 | 0.1841 | 0.0001 | 0.0003 | 0.0002 | 0.0008 | 0.0015 | 0.0014 | 0.0077 | 0.0098 | 0.0437 | 0.0330 | 0.0678 | 0.0540 | 0.0479 | 0.0450 | 0.0793 | 0.0589 | 0.7519 | 0.7967 | 0.0005 | 0.0000 | 0.0015 | 0.0012 | 0.0026 | 0.0031 | 0.0122 | 0.0151 | 0.0611 | 0.0727 | 0.0953 | 0.1124 | 0.0662 | 0.0769 | 0.1035 | 0.1141 | 0.6570 | 0.6045 | 0.0001 | 0.0010 | 0.0024 | 0.0121 | 0.0486 | 0.0835 | 0.0554 | 0.0881 | 0.7087 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 199 | 260 | | 10686 | 24087 | 343.1 | 42.34 | 218.62 | 243.80 | 294 | 309 | 319 | 329 | 339 | 349 | 361 | 376 | 398 | 0.0560 | 1348 | 1.108 | 80.65 | 27.02 | 2 | 0.0188 | 201 | 0.0020 | 20.94 | 6.553 | 0.2495 | 119532.0 | 42300000 | 15200000000 | 5550000000000 | 0.4430 | 0.2105 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0032 | 0.0005 | 0.0194 | 0.0089 | 0.0355 | 0.0176 | 0.0461 | 0.0113 | 0.0755 | 0.0211 | 0.8188 | 0.9407 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0015 | 0.0000 | 0.0114 | 0.0086 | 0.0212 | 0.0159 | 0.0232 | 0.0077 | 0.0352 | 0.0146 | 0.9074 | 0.9532 | 0.0199 | 0.0000 | 0.0385 | 0.0000 | 0.0442 | 0.0000 | 0.0855 | 0.0000 | 0.0954 | 0.0000 | 0.1311 | 0.0000 | 0.1197 | 0.0000 | 0.1211 | 0.0000 | 0.3447 | 0.0000 | 0.0047 | 0.0098 | 0.0155 | 0.0422 | 0.0674 | 0.0986 | 0.1131 | 0.1277 | 0.5211 | 18 | 23 | 29 | 46 | 110 | 198 | 297 | 422 | 589 | 0.0307 | 46.12 | 5.951 | 0.4302 | 107227.0 | 68300000 | 50200000000 | 40800000000000 | 0.5298 | 0.1259 | 0.0245 | 0.0018 | 0.1127 | 0.0149 | 0.2277 | 0.0610 | 0.1750 | 0.0972 | 0.1550 | 0.1809 | 0.1245 | 0.2068 | 0.0732 | 0.1277 | 0.0609 | 0.1204 | 0.0464 | 0.1894 | 0.0000 | 0.0000 | 0.0005 | 0.0002 | 0.0017 | 0.0016 | 0.0077 | 0.0073 | 0.0415 | 0.0338 | 0.0707 | 0.0588 | 0.0495 | 0.0417 | 0.0772 | 0.0625 | 0.7513 | 0.7941 | 0.0004 | 0.0004 | 0.0010 | 0.0016 | 0.0029 | 0.0041 | 0.0139 | 0.0205 | 0.0578 | 0.0653 | 0.0903 | 0.1105 | 0.0763 | 0.0890 | 0.1087 | 0.1110 | 0.6487 | 0.5975 | 0.0001 | 0.0011 | 0.0034 | 0.0105 | 0.0471 | 0.0826 | 0.0615 | 0.0887 | 0.7050 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 854 | 416 | | 11131 | 15417 | 454.3 | 71.88 | 90.38 | 157.98 | 358 | 393 | 418 | 438 | 454 | 468 | 484 | 508 | 549 | 0.0688 | 1061 | 1.159 | 147.22 | 49.48 | 2 | 0.0314 | 350 | 0.0013 | 17.13 | 6.964 | 0.2615 | 211570.0 | 101000000 | 49300000000 | 24600000000000 | 0.4019 | 0.2435 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0025 | 0.0005 | 0.0056 | 0.0007 | 0.0198 | 0.0107 | 0.0364 | 0.0188 | 0.0370 | 0.0124 | 0.0542 | 0.0178 | 0.8429 | 0.9388 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0023 | 0.0002 | 0.0110 | 0.0093 | 0.0213 | 0.0169 | 0.0198 | 0.0089 | 0.0278 | 0.0138 | 0.9153 | 0.9509 | 0.0058 | 0.0159 | 0.0075 | 0.0397 | 0.0100 | 0.0556 | 0.0325 | 0.1270 | 0.0600 | 0.0873 | 0.0783 | 0.1349 | 0.0666 | 0.1111 | 0.0966 | 0.0952 | 0.6428 | 0.3333 | 0.0012 | 0.0023 | 0.0068 | 0.0178 | 0.0371 | 0.0570 | 0.0697 | 0.0892 | 0.7189 | 7 | 9 | 10 | 11 | 14 | 23 | 53 | 139 | 311 | 0.2296 | 12.11 | 3.590 | 0.7091 | 33126.6 | 17600000 | 11100000000 | 7920000000000 | 0.5835 | 0.1060 | 0.0228 | 0.0066 | 0.0791 | 0.0185 | 0.1263 | 0.0524 | 0.1948 | 0.0739 | 0.1933 | 0.1344 | 0.1522 | 0.1839 | 0.0898 | 0.1440 | 0.0883 | 0.1322 | 0.0533 | 0.2541 | 0.0000 | 0.0006 | 0.0012 | 0.0017 | 0.0021 | 0.0039 | 0.0062 | 0.0067 | 0.0321 | 0.0323 | 0.0482 | 0.0424 | 0.0349 | 0.0336 | 0.0634 | 0.0528 | 0.8120 | 0.8259 | 0.0011 | 0.0003 | 0.0031 | 0.0018 | 0.0025 | 0.0028 | 0.0098 | 0.0104 | 0.0419 | 0.0429 | 0.0613 | 0.0726 | 0.0526 | 0.0643 | 0.0793 | 0.0867 | 0.7482 | 0.7182 | 0.0003 | 0.0013 | 0.0028 | 0.0103 | 0.0339 | 0.0573 | 0.0419 | 0.0637 | 0.7885 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 439 | | 9462 | 17615 | 66.2 | 18.80 | 11.63 | 7.94 | 45 | 48 | 51 | 57 | 63 | 69 | 76 | 85 | 93 | 0.0582 | 1025 | 0.806 | 93.06 | 26.68 | 0 | 0.0260 | 246 | 0.0396 | 0.80 | 3.627 | 0.7208 | 4738.0 | 364637 | 29900000 | 2590000000 | 0.4090 | 0.2322 | 0.0114 | 0.0009 | 0.0137 | 0.0014 | 0.0190 | 0.0032 | 0.0307 | 0.0089 | 0.0497 | 0.0193 | 0.0678 | 0.0417 | 0.0898 | 0.0415 | 0.1269 | 0.0742 | 0.5909 | 0.8088 | 0.0052 | 0.0000 | 0.0064 | 0.0002 | 0.0081 | 0.0003 | 0.0109 | 0.0024 | 0.0165 | 0.0081 | 0.0215 | 0.0205 | 0.0284 | 0.0132 | 0.0370 | 0.0319 | 0.8659 | 0.9234 | 0.0061 | 0.0140 | 0.0065 | 0.0220 | 0.0105 | 0.0451 | 0.0252 | 0.0762 | 0.0304 | 0.1062 | 0.0527 | 0.1333 | 0.0641 | 0.1283 | 0.0933 | 0.1413 | 0.7112 | 0.3337 | 0.0026 | 0.0049 | 0.0086 | 0.0123 | 0.0283 | 0.0339 | 0.0416 | 0.0706 | 0.7972 | 5 | 6 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 0.2867 | 0.33 | 1.922 | 0.8442 | 198.3 | 4862.52 | 154893 | 5820000 | 0.5138 | 0.1400 | 0.0871 | 0.0128 | 0.1401 | 0.0280 | 0.1505 | 0.0586 | 0.1491 | 0.0912 | 0.1521 | 0.1375 | 0.1294 | 0.1665 | 0.1167 | 0.1770 | 0.0606 | 0.1781 | 0.0146 | 0.1503 | 0.0408 | 0.0059 | 0.0668 | 0.0174 | 0.0671 | 0.0381 | 0.0575 | 0.0614 | 0.0582 | 0.0937 | 0.0540 | 0.1156 | 0.0645 | 0.1142 | 0.0925 | 0.1136 | 0.4986 | 0.4402 | 0.0246 | 0.0157 | 0.0222 | 0.0242 | 0.0309 | 0.0310 | 0.0415 | 0.0336 | 0.0492 | 0.0529 | 0.0632 | 0.0663 | 0.0719 | 0.0777 | 0.1169 | 0.1326 | 0.5796 | 0.5660 | 0.0564 | 0.0389 | 0.0353 | 0.0306 | 0.0484 | 0.0603 | 0.0728 | 0.0984 | 0.5589 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 913 | 210 | | 8143 | 27204 | 304.1 | 75.81 | 255.15 | 302.47 | 195 | 245 | 273 | 292 | 310 | 328 | 348 | 371 | 396 | 0.0396 | 1076 | 1.114 | 110.82 | 43.01 | 5 | 0.0373 | 304 | 0.0010 | 29.98 | 7.166 | 0.2157 | 98209.8 | 33200000 | 11600000000 | 4170000000000 | 0.4037 | 0.2325 | 0.0006 | 0.0000 | 0.0017 | 0.0000 | 0.0087 | 0.0001 | 0.0205 | 0.0021 | 0.0499 | 0.0164 | 0.0838 | 0.0287 | 0.0889 | 0.0302 | 0.1235 | 0.0508 | 0.6224 | 0.8717 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0037 | 0.0011 | 0.0125 | 0.0105 | 0.0220 | 0.0168 | 0.0235 | 0.0118 | 0.0341 | 0.0168 | 0.9030 | 0.9431 | 0.0027 | 0.0366 | 0.0038 | 0.0549 | 0.0215 | 0.0623 | 0.0447 | 0.1282 | 0.0910 | 0.2051 | 0.1319 | 0.1722 | 0.1179 | 0.1612 | 0.1524 | 0.0989 | 0.4340 | 0.0806 | 0.0014 | 0.0032 | 0.0069 | 0.0123 | 0.0407 | 0.0638 | 0.0782 | 0.0981 | 0.6954 | 11 | 17 | 29 | 55 | 110 | 207 | 346 | 511 | 718 | 0.0322 | 37.90 | 6.066 | 0.4425 | 156585.0 | 127000000 | 124000000000 | 141000000000000 | 0.4560 | 0.1894 | 0.0158 | 0.0005 | 0.0981 | 0.0072 | 0.2220 | 0.0341 | 0.1823 | 0.1004 | 0.1923 | 0.1873 | 0.1306 | 0.2205 | 0.0775 | 0.1404 | 0.0464 | 0.1380 | 0.0349 | 0.1716 | 0.0002 | 0.0001 | 0.0006 | 0.0008 | 0.0034 | 0.0020 | 0.0077 | 0.0080 | 0.0389 | 0.0364 | 0.0615 | 0.0565 | 0.0439 | 0.0435 | 0.0653 | 0.0602 | 0.7784 | 0.7924 | 0.0005 | 0.0004 | 0.0011 | 0.0013 | 0.0019 | 0.0025 | 0.0109 | 0.0122 | 0.0412 | 0.0488 | 0.0778 | 0.0819 | 0.0567 | 0.0645 | 0.0835 | 0.0869 | 0.7263 | 0.7017 | 0.0003 | 0.0012 | 0.0026 | 0.0088 | 0.0373 | 0.0681 | 0.0507 | 0.0713 | 0.7596 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 349 | 807 | | 6538 | 12626 | 588.0 | 86.69 | 128.31 | 222.66 | 469 | 530 | 562 | 584 | 602 | 620 | 637 | 657 | 683 | 0.0673 | 850 | 0.775 | 146.56 | 30.15 | 1 | 0.0509 | 333 | 0.0010 | 44.42 | 7.238 | 0.1938 | 353259.0 | 216000000 | 134000000000 | 83900000000000 | 0.4229 | 0.2180 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0002 | 0.0197 | 0.0106 | 0.0355 | 0.0173 | 0.0365 | 0.0112 | 0.0673 | 0.0176 | 0.8370 | 0.9433 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0129 | 0.0106 | 0.0221 | 0.0173 | 0.0201 | 0.0112 | 0.0312 | 0.0176 | 0.9121 | 0.9433 | 0.0276 | 0.0000 | 0.0379 | 0.0000 | 0.0379 | 0.0000 | 0.1241 | 0.0000 | 0.1310 | 0.0000 | 0.1586 | 0.0000 | 0.1241 | 0.0000 | 0.0931 | 0.0000 | 0.2655 | 0.0000 | 0.0011 | 0.0034 | 0.0053 | 0.0169 | 0.0344 | 0.0573 | 0.0655 | 0.0922 | 0.7238 | 11 | 13 | 16 | 21 | 29 | 46 | 87 | 188 | 404 | 0.1397 | 11.93 | 3.675 | 0.6149 | 66036.9 | 54600000 | 58200000000 | 74400000000000 | 0.4876 | 0.1751 | 0.0820 | 0.0077 | 0.2182 | 0.0463 | 0.2753 | 0.1683 | 0.1406 | 0.1143 | 0.1083 | 0.1550 | 0.0849 | 0.1907 | 0.0395 | 0.1066 | 0.0249 | 0.0863 | 0.0264 | 0.1248 | 0.0000 | 0.0005 | 0.0009 | 0.0010 | 0.0026 | 0.0022 | 0.0131 | 0.0124 | 0.0707 | 0.0604 | 0.0993 | 0.0897 | 0.0678 | 0.0592 | 0.1013 | 0.0905 | 0.6443 | 0.6841 | 0.0000 | 0.0004 | 0.0004 | 0.0004 | 0.0039 | 0.0019 | 0.0218 | 0.0250 | 0.0761 | 0.0832 | 0.1208 | 0.1271 | 0.0778 | 0.0847 | 0.1127 | 0.1144 | 0.5866 | 0.5630 | 0.0003 | 0.0003 | 0.0029 | 0.0147 | 0.0809 | 0.1055 | 0.0723 | 0.1125 | 0.6106 |
| Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1109 | 467 | | 7728 | 10985 | 187.4 | 61.96 | 106.16 | 170.18 | 109 | 128 | 147 | 169 | 186 | 203 | 220 | 239 | 268 | 0.0861 | 946 | 1.180 | 100.90 | 29.02 | 3 | 0.0294 | 227 | 0.0011 | 27.43 | 7.104 | 0.2644 | 38959.5 | 8810000 | 2140000000 | 549000000000 | 0.4404 | 0.1893 | 0.0019 | 0.0005 | 0.0066 | 0.0013 | 0.0109 | 0.0023 | 0.0241 | 0.0084 | 0.0675 | 0.0240 | 0.0947 | 0.0473 | 0.0944 | 0.0455 | 0.1310 | 0.0624 | 0.5688 | 0.8083 | 0.0006 | 0.0003 | 0.0015 | 0.0009 | 0.0032 | 0.0012 | 0.0043 | 0.0039 | 0.0171 | 0.0115 | 0.0221 | 0.0195 | 0.0225 | 0.0169 | 0.0332 | 0.0232 | 0.8955 | 0.9226 | 0.0028 | 0.0045 | 0.0052 | 0.0034 | 0.0131 | 0.0101 | 0.0197 | 0.0515 | 0.0553 | 0.1074 | 0.0933 | 0.1398 | 0.0778 | 0.1040 | 0.1172 | 0.1275 | 0.6157 | 0.4519 | 0.0003 | 0.0005 | 0.0034 | 0.0120 | 0.0330 | 0.0494 | 0.0546 | 0.0738 | 0.7730 | 10 | 13 | 16 | 20 | 29 | 52 | 97 | 156 | 295 | 0.0735 | 19.46 | 4.540 | 0.5815 | 40229.5 | 25000000 | 19500000000 | 17300000000000 | 0.4726 | 0.1847 | 0.0486 | 0.0029 | 0.0972 | 0.0161 | 0.1627 | 0.0732 | 0.1333 | 0.0992 | 0.1345 | 0.1522 | 0.1390 | 0.1690 | 0.0949 | 0.1107 | 0.0836 | 0.1148 | 0.1062 | 0.2618 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0042 | 0.0027 | 0.0152 | 0.0126 | 0.0576 | 0.0567 | 0.0829 | 0.0680 | 0.0576 | 0.0508 | 0.0880 | 0.0841 | 0.6936 | 0.7242 | 0.0007 | 0.0009 | 0.0045 | 0.0047 | 0.0064 | 0.0108 | 0.0288 | 0.0284 | 0.0804 | 0.0814 | 0.0932 | 0.1063 | 0.0718 | 0.0689 | 0.1044 | 0.1029 | 0.6098 | 0.5958 | 0.0003 | 0.0019 | 0.0055 | 0.0183 | 0.0685 | 0.0985 | 0.0711 | 0.1046 | 0.6313 | ||
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 911 | 863 | | 3384 | 11761 | 420.9 | 86.47 | 4.73 | 2.08 | 302 | 339 | 369 | 396 | 423 | 445 | 469 | 496 | 541 | 0.0709 | 834 | 1.119 | 147.57 | 40.85 | 2 | 0.0999 | 338 | 0.0022 | 9.37 | 6.372 | 0.3153 | 184655.0 | 84100000 | 39600000000 | 19200000000000 | 0.4075 | 0.2262 | 0.0000 | 0.0000 | 0.0009 | 0.0003 | 0.0028 | 0.0009 | 0.0122 | 0.0018 | 0.0380 | 0.0163 | 0.0576 | 0.0317 | 0.0595 | 0.0211 | 0.0792 | 0.0350 | 0.7498 | 0.8928 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0044 | 0.0012 | 0.0176 | 0.0145 | 0.0223 | 0.0252 | 0.0223 | 0.0145 | 0.0318 | 0.0228 | 0.9012 | 0.9217 | 0.0017 | 0.0164 | 0.0067 | 0.0820 | 0.0151 | 0.1148 | 0.0334 | 0.0656 | 0.0552 | 0.1475 | 0.0970 | 0.1967 | 0.0719 | 0.0984 | 0.1070 | 0.1148 | 0.6120 | 0.1639 | 0.0006 | 0.0006 | 0.0041 | 0.0122 | 0.0232 | 0.0313 | 0.0481 | 0.0614 | 0.8188 | 3 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 8 | 0.1884 | 0.49 | 1.040 | 0.5055 | 26.7 | 168.516 | 1167.32 | 8724.82 | 0.5573 | 0.1272 | 0.0310 | 0.0008 | 0.1092 | 0.0058 | 0.1823 | 0.0231 | 0.2315 | 0.0675 | 0.2131 | 0.1372 | 0.1494 | 0.2192 | 0.0658 | 0.2642 | 0.0165 | 0.2065 | 0.0011 | 0.0758 | 0.0004 | 0.0000 | 0.0062 | 0.0001 | 0.0262 | 0.0023 | 0.0677 | 0.0103 | 0.1256 | 0.0273 | 0.1932 | 0.0570 | 0.2350 | 0.1221 | 0.2198 | 0.2928 | 0.1259 | 0.4881 | 0.0687 | 0.1947 | 0.1761 | 0.2643 | 0.2285 | 0.2297 | 0.2191 | 0.1457 | 0.1708 | 0.0988 | 0.0955 | 0.0490 | 0.0325 | 0.0152 | 0.0079 | 0.0021 | 0.0008 | 0.0004 | 0.0121 | 0.0572 | 0.1283 | 0.1756 | 0.2122 | 0.1867 | 0.1313 | 0.0730 | 0.0235 | ||
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1161 | 623 | | 4896 | 12890 | 292.1 | 122.93 | 77.58 | 156.83 | 140 | 170 | 195 | 234 | 275 | 322 | 378 | 426 | 471 | 0.0714 | 920 | 0.771 | 63.56 | 16.03 | 4 | 0.0327 | 160 | 0.0010 | 16.01 | 7.132 | 0.2695 | 100453.0 | 38700000 | 16000000000 | 6940000000000 | 0.3486 | 0.2680 | 0.0008 | 0.0004 | 0.0008 | 0.0015 | 0.0008 | 0.0030 | 0.0194 | 0.0109 | 0.0891 | 0.0449 | 0.1336 | 0.0612 | 0.1263 | 0.0581 | 0.1571 | 0.0849 | 0.4721 | 0.7350 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0003 | 0.0018 | 0.0061 | 0.0047 | 0.0187 | 0.0171 | 0.0224 | 0.0237 | 0.0252 | 0.0179 | 0.0330 | 0.0339 | 0.8936 | 0.9006 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0035 | 0.0053 | 0.0087 | 0.0381 | 0.0582 | 0.0545 | 0.0582 | 0.0393 | 0.0616 | 0.0527 | 0.0851 | 0.8102 | 0.7240 | 0.0000 | 0.0004 | 0.0009 | 0.0035 | 0.0274 | 0.0363 | 0.0314 | 0.0456 | 0.8544 | 7 | 9 | 11 | 13 | 17 | 25 | 42 | 84 | 223 | 0.1061 | 17.09 | 3.929 | 0.6640 | 30613.2 | 21000000 | 18400000000 | 18500000000000 | 0.3956 | 0.2278 | 0.0335 | 0.0066 | 0.0911 | 0.0183 | 0.1580 | 0.0374 | 0.2026 | 0.0682 | 0.2286 | 0.1364 | 0.1283 | 0.1540 | 0.1022 | 0.1393 | 0.0353 | 0.1598 | 0.0204 | 0.2801 | 0.0027 | 0.0025 | 0.0047 | 0.0030 | 0.0047 | 0.0050 | 0.0097 | 0.0116 | 0.0484 | 0.0449 | 0.0684 | 0.0581 | 0.0494 | 0.0512 | 0.0735 | 0.0722 | 0.7386 | 0.7516 | 0.0004 | 0.0009 | 0.0004 | 0.0004 | 0.0033 | 0.0035 | 0.0114 | 0.0097 | 0.0521 | 0.0578 | 0.0720 | 0.0843 | 0.0606 | 0.0618 | 0.0781 | 0.0856 | 0.7216 | 0.6961 | 0.0004 | 0.0011 | 0.0026 | 0.0086 | 0.0474 | 0.0784 | 0.0523 | 0.0732 | 0.7359 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 817 | | 5202 | 13328 | 498.6 | 85.62 | 75.42 | 193.51 | 376 | 424 | 460 | 483 | 503 | 525 | 551 | 573 | 600 | 0.0606 | 808 | 0.924 | 121.38 | 32.28 | 1 | 0.0600 | 312 | 0.0016 | 14.59 | 6.726 | 0.2939 | 255905.0 | 135000000 | 72700000000 | 40000000000000 | 0.4179 | 0.2243 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0023 | 0.0002 | 0.0100 | 0.0010 | 0.0267 | 0.0117 | 0.0460 | 0.0271 | 0.0409 | 0.0125 | 0.0779 | 0.0230 | 0.7949 | 0.9246 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0007 | 0.0000 | 0.0041 | 0.0008 | 0.0129 | 0.0112 | 0.0226 | 0.0247 | 0.0142 | 0.0106 | 0.0293 | 0.0185 | 0.9158 | 0.9342 | 0.0074 | 0.0227 | 0.0185 | 0.0000 | 0.0444 | 0.0455 | 0.0628 | 0.0455 | 0.0795 | 0.1591 | 0.1109 | 0.1364 | 0.1146 | 0.1136 | 0.1109 | 0.1364 | 0.4510 | 0.3409 | 0.0022 | 0.0041 | 0.0081 | 0.0144 | 0.0276 | 0.0398 | 0.0446 | 0.0692 | 0.7901 | 8 | 10 | 11 | 12 | 14 | 17 | 27 | 59 | 186 | 0.2830 | 9.88 | 2.941 | 0.7317 | 43131.2 | 46900000 | 63500000000 | 95400000000000 | 0.3571 | 0.2342 | 0.0717 | 0.0047 | 0.2131 | 0.0292 | 0.2384 | 0.1318 | 0.1751 | 0.1111 | 0.1245 | 0.1770 | 0.0802 | 0.2062 | 0.0422 | 0.1234 | 0.0295 | 0.1036 | 0.0253 | 0.1130 | 0.0008 | 0.0003 | 0.0011 | 0.0036 | 0.0019 | 0.0062 | 0.0121 | 0.0147 | 0.0524 | 0.0421 | 0.0746 | 0.0718 | 0.0543 | 0.0492 | 0.0758 | 0.0744 | 0.7271 | 0.7378 | 0.0000 | 0.0005 | 0.0009 | 0.0010 | 0.0023 | 0.0025 | 0.0138 | 0.0125 | 0.0555 | 0.0609 | 0.0909 | 0.0973 | 0.0564 | 0.0579 | 0.0844 | 0.0868 | 0.6957 | 0.6806 | 0.0004 | 0.0017 | 0.0008 | 0.0138 | 0.0522 | 0.0823 | 0.0547 | 0.0852 | 0.7090 | ||
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 685 | | 3310 | 17319 | 115.5 | 44.52 | 5.43 | 1.99 | 62 | 70 | 80 | 93 | 109 | 124 | 140 | 161 | 181 | 0.0577 | 999 | 0.991 | 31.40 | 10.77 | 2 | 0.0266 | 88 | 0.0050 | 4.21 | 5.619 | 0.4414 | 15310.3 | 2260000 | 362000000 | 61100000000 | 0.3498 | 0.2779 | 0.0021 | 0.0010 | 0.0072 | 0.0039 | 0.0123 | 0.0093 | 0.0349 | 0.0181 | 0.0739 | 0.0366 | 0.1242 | 0.0439 | 0.1232 | 0.0649 | 0.1828 | 0.0825 | 0.4394 | 0.7399 | 0.0005 | 0.0007 | 0.0015 | 0.0026 | 0.0035 | 0.0048 | 0.0089 | 0.0096 | 0.0212 | 0.0177 | 0.0227 | 0.0184 | 0.0257 | 0.0302 | 0.0420 | 0.0350 | 0.8741 | 0.8809 | 0.0010 | 0.0000 | 0.0019 | 0.0045 | 0.0086 | 0.0106 | 0.0209 | 0.0151 | 0.0409 | 0.0452 | 0.0571 | 0.0603 | 0.0523 | 0.0724 | 0.0647 | 0.0799 | 0.7526 | 0.7119 | 0.0013 | 0.0000 | 0.0013 | 0.0097 | 0.0232 | 0.0387 | 0.0290 | 0.0574 | 0.8395 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.2714 | 0.47 | 1.049 | 0.6358 | 33.5 | 227.156 | 1669.44 | 13153.9 | 0.4485 | 0.2089 | 0.0313 | 0.0023 | 0.0940 | 0.0125 | 0.1602 | 0.0406 | 0.2077 | 0.0829 | 0.2080 | 0.1416 | 0.1737 | 0.2164 | 0.0888 | 0.2463 | 0.0321 | 0.1826 | 0.0043 | 0.0747 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0030 | 0.0008 | 0.0099 | 0.0050 | 0.0301 | 0.0153 | 0.0780 | 0.0258 | 0.2017 | 0.0630 | 0.3485 | 0.2345 | 0.3287 | 0.6554 | 0.0177 | 0.0768 | 0.0775 | 0.1643 | 0.1302 | 0.2136 | 0.1742 | 0.2130 | 0.1942 | 0.1573 | 0.1860 | 0.0951 | 0.1327 | 0.0548 | 0.0683 | 0.0195 | 0.0192 | 0.0057 | 0.0007 | 0.0109 | 0.0459 | 0.1123 | 0.1876 | 0.2387 | 0.2118 | 0.1393 | 0.0528 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1097 | 888 | | 12238 | 26075 | 289.7 | 37.50 | 189.36 | 227.04 | 244 | 259 | 270 | 279 | 288 | 297 | 306 | 319 | 339 | 0.0439 | 1145 | 0.830 | 88.09 | 22.20 | 1 | 0.0187 | 229 | 0.0028 | 13.76 | 6.262 | 0.2992 | 85311.3 | 25500000 | 7770000000 | 2410000000000 | 0.4323 | 0.2203 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0020 | 0.0000 | 0.0060 | 0.0003 | 0.0185 | 0.0078 | 0.0396 | 0.0156 | 0.0439 | 0.0098 | 0.0748 | 0.0169 | 0.8146 | 0.9496 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0001 | 0.0111 | 0.0076 | 0.0227 | 0.0147 | 0.0220 | 0.0071 | 0.0372 | 0.0112 | 0.9046 | 0.9593 | 0.0133 | 0.0000 | 0.0200 | 0.0000 | 0.0333 | 0.0000 | 0.0765 | 0.0000 | 0.1109 | 0.0000 | 0.1408 | 0.0000 | 0.1264 | 0.0000 | 0.1574 | 0.0000 | 0.3215 | 0.0000 | 0.0025 | 0.0088 | 0.0142 | 0.0239 | 0.0616 | 0.0902 | 0.0999 | 0.1291 | 0.5696 | 14 | 17 | 21 | 38 | 82 | 149 | 243 | 368 | 535 | 0.0346 | 41.52 | 5.730 | 0.4531 | 87402.9 | 53700000 | 38800000000 | 31400000000000 | 0.4360 | 0.2156 | 0.0618 | 0.0023 | 0.2087 | 0.0236 | 0.2420 | 0.1370 | 0.1346 | 0.1541 | 0.1098 | 0.1754 | 0.0927 | 0.1578 | 0.0590 | 0.0979 | 0.0495 | 0.0906 | 0.0418 | 0.1614 | 0.0001 | 0.0003 | 0.0003 | 0.0006 | 0.0015 | 0.0013 | 0.0103 | 0.0092 | 0.0495 | 0.0407 | 0.0808 | 0.0715 | 0.0648 | 0.0501 | 0.0944 | 0.0787 | 0.6983 | 0.7478 | 0.0000 | 0.0003 | 0.0007 | 0.0015 | 0.0026 | 0.0033 | 0.0159 | 0.0223 | 0.0664 | 0.0710 | 0.1136 | 0.1319 | 0.0845 | 0.0978 | 0.1225 | 0.1311 | 0.5939 | 0.5409 | 0.0004 | 0.0007 | 0.0021 | 0.0134 | 0.0562 | 0.0948 | 0.0755 | 0.1060 | 0.6510 |