High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 100 | 607 | | 540 | 5580 | 379.2 | 43.12 | 73.69 | 167.23 | 318 | 337 | 353 | 372 | 384 | 393 | 405 | 418 | 436 | 0.0710 | 396 | 0.750 | 109.88 | 35.01 | 2 | 0.6222 | 336 | 0.0034 | 25.50 | 5.823 | 0.2191 | 145633.0 | 56600000 | 22300000000 | 8850000000000 | 0.3869 | 0.2443 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0080 | 0.0019 | 0.0459 | 0.0426 | 0.0719 | 0.0630 | 0.0599 | 0.0315 | 0.0719 | 0.0537 | 0.7405 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0039 | 0.0019 | 0.0426 | 0.0426 | 0.0638 | 0.0630 | 0.0329 | 0.0315 | 0.0561 | 0.0537 | 0.7988 | 0.8074 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0625 | 0.0000 | 0.1250 | 0.0000 | 0.4375 | 0.0000 | 0.0625 | 0.0000 | 0.2500 | 0.0000 | 0.0625 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0241 | 0.0552 | 0.0897 | 0.0828 | 0.1276 | 0.6138 | 10 | 13 | 15 | 17 | 20 | 25 | 42 | 99 | 162 | 0.2249 | 3.67 | 2.655 | 0.7483 | 33390.0 | 36400000 | 52700000000 | 84800000000000 | 0.5879 | 0.1256 | 0.0385 | 0.0052 | 0.0427 | 0.0174 | 0.1026 | 0.0261 | 0.1880 | 0.0540 | 0.2222 | 0.1237 | 0.1624 | 0.1429 | 0.1496 | 0.1655 | 0.0684 | 0.2003 | 0.0256 | 0.2648 | 0.0007 | 0.0018 | 0.0014 | 0.0043 | 0.0027 | 0.0037 | 0.0075 | 0.0043 | 0.0177 | 0.0178 | 0.0198 | 0.0227 | 0.0355 | 0.0233 | 0.0539 | 0.0491 | 0.8608 | 0.8729 | 0.0000 | 0.0038 | 0.0000 | 0.0028 | 0.0000 | 0.0066 | 0.0154 | 0.0227 | 0.0292 | 0.0360 | 0.0382 | 0.0588 | 0.0544 | 0.0682 | 0.1072 | 0.0986 | 0.7555 | 0.7024 | 0.0007 | 0.0007 | 0.0029 | 0.0059 | 0.0192 | 0.0354 | 0.0347 | 0.0560 | 0.8444 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 307 | 284 | | 4454 | 15705 | 541.8 | 126.10 | 114.66 | 191.51 | 395 | 434 | 463 | 491 | 521 | 551 | 591 | 651 | 728 | 0.0554 | 870 | 1.060 | 102.88 | 27.59 | 2 | 0.0534 | 238 | 0.0008 | 82.33 | 7.369 | 0.1665 | 309466.0 | 186000000 | 118000000000 | 78000000000000 | 0.4066 | 0.2345 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0097 | 0.0005 | 0.0157 | 0.0027 | 0.0737 | 0.0261 | 0.1377 | 0.0438 | 0.1448 | 0.0443 | 0.1534 | 0.0597 | 0.4611 | 0.8229 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0056 | 0.0002 | 0.0407 | 0.0161 | 0.0709 | 0.0258 | 0.0709 | 0.0192 | 0.0895 | 0.0269 | 0.7210 | 0.9117 | 0.0022 | 0.0032 | 0.0000 | 0.0160 | 0.0078 | 0.0415 | 0.0526 | 0.0927 | 0.0973 | 0.1629 | 0.1353 | 0.1502 | 0.0839 | 0.1086 | 0.1074 | 0.1438 | 0.5134 | 0.2812 | 0.0000 | 0.0031 | 0.0062 | 0.0333 | 0.0868 | 0.1149 | 0.1004 | 0.1108 | 0.5445 | 5 | 7 | 8 | 10 | 11 | 17 | 98 | 220 | 400 | 0.1818 | 28.75 | 4.115 | 0.6043 | 49820.4 | 29100000 | 19900000000 | 15300000000000 | 0.3528 | 0.2965 | 0.0222 | 0.0027 | 0.0974 | 0.0054 | 0.2530 | 0.0467 | 0.2085 | 0.0916 | 0.1880 | 0.2163 | 0.1333 | 0.2720 | 0.0496 | 0.1517 | 0.0222 | 0.1086 | 0.0256 | 0.1050 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0010 | 0.0002 | 0.0025 | 0.0028 | 0.0223 | 0.0206 | 0.0377 | 0.0307 | 0.0289 | 0.0256 | 0.0466 | 0.0365 | 0.8607 | 0.8834 | 0.0005 | 0.0003 | 0.0002 | 0.0005 | 0.0002 | 0.0005 | 0.0059 | 0.0071 | 0.0334 | 0.0374 | 0.0541 | 0.0695 | 0.0498 | 0.0450 | 0.0636 | 0.0730 | 0.7923 | 0.7666 | 0.0002 | 0.0000 | 0.0004 | 0.0042 | 0.0271 | 0.0491 | 0.0391 | 0.0560 | 0.8237 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 710 | 226 | | 10638 | 31624 | 385.7 | 96.25 | 128.74 | 201.92 | 261 | 301 | 330 | 358 | 383 | 410 | 437 | 468 | 511 | 0.0395 | 1248 | 1.125 | 80.96 | 32.70 | 1 | 0.0205 | 218 | 0.0007 | 46.96 | 7.474 | 0.1736 | 158052.0 | 68300000 | 30900000000 | 14600000000000 | 0.4592 | 0.1972 | 0.0007 | 0.0000 | 0.0012 | 0.0000 | 0.0092 | 0.0002 | 0.0215 | 0.0023 | 0.0807 | 0.0217 | 0.1548 | 0.0477 | 0.1521 | 0.0530 | 0.1775 | 0.0756 | 0.4023 | 0.7994 | 0.0004 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0071 | 0.0011 | 0.0308 | 0.0141 | 0.0563 | 0.0286 | 0.0517 | 0.0248 | 0.0718 | 0.0362 | 0.7784 | 0.8951 | 0.0031 | 0.0050 | 0.0093 | 0.0268 | 0.0194 | 0.0385 | 0.0552 | 0.1122 | 0.1254 | 0.2111 | 0.1762 | 0.1960 | 0.1219 | 0.1122 | 0.1524 | 0.1374 | 0.3370 | 0.1608 | 0.0006 | 0.0025 | 0.0046 | 0.0208 | 0.0594 | 0.1029 | 0.0892 | 0.1124 | 0.6077 | 6 | 7 | 8 | 10 | 13 | 26 | 121 | 273 | 445 | 0.1884 | 22.33 | 4.262 | 0.6114 | 57343.9 | 33100000 | 22000000000 | 16300000000000 | 0.4979 | 0.1312 | 0.0634 | 0.0031 | 0.2215 | 0.0274 | 0.3281 | 0.1449 | 0.1801 | 0.1860 | 0.1167 | 0.2111 | 0.0542 | 0.1939 | 0.0193 | 0.0950 | 0.0119 | 0.0923 | 0.0046 | 0.0464 | 0.0001 | 0.0002 | 0.0001 | 0.0007 | 0.0014 | 0.0009 | 0.0035 | 0.0033 | 0.0325 | 0.0296 | 0.0490 | 0.0435 | 0.0394 | 0.0311 | 0.0566 | 0.0537 | 0.8173 | 0.8370 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0002 | 0.0006 | 0.0049 | 0.0057 | 0.0367 | 0.0435 | 0.0707 | 0.0771 | 0.0468 | 0.0543 | 0.0747 | 0.0844 | 0.7660 | 0.7341 | 0.0000 | 0.0002 | 0.0005 | 0.0052 | 0.0314 | 0.0597 | 0.0456 | 0.0609 | 0.7964 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1164 | 748 | | 6717 | 22463 | 231.2 | 47.47 | 136.57 | 200.73 | 173 | 191 | 204 | 215 | 227 | 239 | 252 | 268 | 296 | 0.0526 | 1181 | 0.934 | 159.62 | 41.01 | 1 | 0.0582 | 391 | 0.0009 | 55.53 | 7.264 | 0.1600 | 55703.1 | 14000000 | 3650000000 | 990000000000 | 0.4604 | 0.1920 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0003 | 0.0127 | 0.0008 | 0.0689 | 0.0184 | 0.1261 | 0.0348 | 0.1510 | 0.0342 | 0.1834 | 0.0606 | 0.4552 | 0.8508 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0001 | 0.0050 | 0.0003 | 0.0314 | 0.0132 | 0.0557 | 0.0204 | 0.0683 | 0.0150 | 0.0944 | 0.0288 | 0.7437 | 0.9222 | 0.0094 | 0.0220 | 0.0122 | 0.0293 | 0.0300 | 0.0549 | 0.0880 | 0.1172 | 0.1451 | 0.2125 | 0.1751 | 0.1978 | 0.1170 | 0.1026 | 0.1517 | 0.1172 | 0.2715 | 0.1465 | 0.0006 | 0.0029 | 0.0095 | 0.0350 | 0.1008 | 0.1316 | 0.1272 | 0.1459 | 0.4464 | 8 | 10 | 11 | 13 | 17 | 50 | 153 | 289 | 440 | 0.1678 | 32.49 | 4.522 | 0.5734 | 58941.1 | 34500000 | 24900000000 | 22000000000000 | 0.4912 | 0.1551 | 0.1222 | 0.0039 | 0.3163 | 0.0380 | 0.3182 | 0.2866 | 0.1251 | 0.2349 | 0.0660 | 0.1696 | 0.0394 | 0.1194 | 0.0089 | 0.0653 | 0.0039 | 0.0443 | 0.0000 | 0.0380 | 0.0000 | 0.0000 | 0.0005 | 0.0001 | 0.0001 | 0.0002 | 0.0044 | 0.0063 | 0.0495 | 0.0387 | 0.0788 | 0.0683 | 0.0580 | 0.0512 | 0.1014 | 0.0836 | 0.7073 | 0.7515 | 0.0000 | 0.0003 | 0.0003 | 0.0005 | 0.0002 | 0.0016 | 0.0104 | 0.0097 | 0.0555 | 0.0675 | 0.1057 | 0.1099 | 0.0760 | 0.0890 | 0.1243 | 0.1280 | 0.6276 | 0.5934 | 0.0000 | 0.0006 | 0.0006 | 0.0083 | 0.0528 | 0.0884 | 0.0720 | 0.1141 | 0.6632 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 708 | 397 | | 15447 | 27394 | 562.4 | 113.78 | 118.30 | 212.73 | 394 | 458 | 507 | 542 | 576 | 606 | 636 | 667 | 703 | 0.0495 | 1356 | 0.896 | 108.19 | 30.00 | 3 | 0.0188 | 291 | 0.0006 | 29.72 | 7.605 | 0.2191 | 329218.0 | 199000000 | 124000000000 | 78600000000000 | 0.3988 | 0.2308 | 0.0014 | 0.0000 | 0.0019 | 0.0001 | 0.0040 | 0.0004 | 0.0105 | 0.0011 | 0.0269 | 0.0087 | 0.0473 | 0.0169 | 0.0485 | 0.0102 | 0.0672 | 0.0157 | 0.7922 | 0.9469 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0001 | 0.0023 | 0.0010 | 0.0107 | 0.0080 | 0.0188 | 0.0166 | 0.0160 | 0.0091 | 0.0204 | 0.0143 | 0.9310 | 0.9510 | 0.0029 | 0.0000 | 0.0095 | 0.0179 | 0.0147 | 0.0536 | 0.0297 | 0.1607 | 0.0612 | 0.1250 | 0.0718 | 0.1071 | 0.0872 | 0.2500 | 0.1213 | 0.1071 | 0.6015 | 0.1786 | 0.0008 | 0.0010 | 0.0032 | 0.0069 | 0.0226 | 0.0401 | 0.0411 | 0.0534 | 0.8309 | 7 | 9 | 10 | 11 | 12 | 15 | 40 | 206 | 467 | 0.3132 | 20.18 | 3.462 | 0.7115 | 59247.2 | 38200000 | 27600000000 | 21600000000000 | 0.5023 | 0.1444 | 0.0436 | 0.0036 | 0.1336 | 0.0128 | 0.2377 | 0.1026 | 0.1744 | 0.1354 | 0.1547 | 0.1810 | 0.1069 | 0.1882 | 0.0675 | 0.1055 | 0.0520 | 0.1119 | 0.0295 | 0.1589 | 0.0000 | 0.0003 | 0.0003 | 0.0004 | 0.0010 | 0.0004 | 0.0058 | 0.0038 | 0.0203 | 0.0189 | 0.0418 | 0.0353 | 0.0301 | 0.0220 | 0.0517 | 0.0418 | 0.8491 | 0.8771 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0058 | 0.0079 | 0.0263 | 0.0302 | 0.0558 | 0.0631 | 0.0452 | 0.0492 | 0.0622 | 0.0705 | 0.8037 | 0.7782 | 0.0000 | 0.0000 | 0.0006 | 0.0049 | 0.0263 | 0.0486 | 0.0405 | 0.0571 | 0.8221 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 841 | 100 | | 7377 | 24941 | 386.3 | 96.75 | 88.88 | 190.82 | 262 | 298 | 330 | 360 | 385 | 408 | 433 | 466 | 515 | 0.0500 | 1246 | 0.563 | 94.76 | 26.17 | 2 | 0.0409 | 302 | 0.0008 | 47.55 | 7.415 | 0.1751 | 158588.0 | 68800000 | 31400000000 | 15000000000000 | 0.4311 | 0.2177 | 0.0002 | 0.0000 | 0.0031 | 0.0005 | 0.0070 | 0.0012 | 0.0283 | 0.0041 | 0.0813 | 0.0252 | 0.1505 | 0.0529 | 0.1401 | 0.0558 | 0.1607 | 0.0799 | 0.4286 | 0.7805 | 0.0000 | 0.0000 | 0.0011 | 0.0001 | 0.0023 | 0.0003 | 0.0099 | 0.0018 | 0.0340 | 0.0163 | 0.0593 | 0.0332 | 0.0508 | 0.0272 | 0.0661 | 0.0402 | 0.7764 | 0.8808 | 0.0040 | 0.0130 | 0.0066 | 0.0238 | 0.0139 | 0.0563 | 0.0615 | 0.0909 | 0.1315 | 0.1970 | 0.1606 | 0.1710 | 0.1269 | 0.1255 | 0.1401 | 0.1299 | 0.3549 | 0.1926 | 0.0005 | 0.0014 | 0.0043 | 0.0220 | 0.0674 | 0.1016 | 0.1003 | 0.1272 | 0.5753 | 4 | 5 | 7 | 8 | 10 | 12 | 18 | 103 | 322 | 0.1971 | 13.23 | 3.393 | 0.6457 | 44309.3 | 31100000 | 25500000000 | 23000000000000 | 0.4510 | 0.1554 | 0.0309 | 0.0028 | 0.1373 | 0.0130 | 0.2921 | 0.0763 | 0.2205 | 0.1516 | 0.1431 | 0.2140 | 0.0986 | 0.1898 | 0.0271 | 0.1395 | 0.0213 | 0.1116 | 0.0290 | 0.1014 | 0.0000 | 0.0003 | 0.0009 | 0.0005 | 0.0007 | 0.0016 | 0.0037 | 0.0063 | 0.0213 | 0.0191 | 0.0374 | 0.0318 | 0.0250 | 0.0278 | 0.0407 | 0.0377 | 0.8703 | 0.8748 | 0.0000 | 0.0002 | 0.0008 | 0.0004 | 0.0004 | 0.0019 | 0.0063 | 0.0064 | 0.0259 | 0.0282 | 0.0468 | 0.0526 | 0.0377 | 0.0404 | 0.0539 | 0.0614 | 0.8281 | 0.8084 | 0.0000 | 0.0004 | 0.0008 | 0.0042 | 0.0213 | 0.0423 | 0.0293 | 0.0477 | 0.8540 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 312 | 733 | | 7233 | 20217 | 523.9 | 88.32 | 192.73 | 354.08 | 412 | 444 | 470 | 496 | 519 | 544 | 571 | 604 | 641 | 0.0504 | 1018 | 1.154 | 114.98 | 42.58 | 1 | 0.0408 | 295 | 0.0018 | 19.88 | 6.575 | 0.2459 | 282245.0 | 156000000 | 88600000000 | 51500000000000 | 0.4172 | 0.2311 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0003 | 0.0114 | 0.0004 | 0.0461 | 0.0113 | 0.0920 | 0.0228 | 0.1143 | 0.0150 | 0.1514 | 0.0291 | 0.5824 | 0.9210 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0046 | 0.0001 | 0.0219 | 0.0096 | 0.0442 | 0.0195 | 0.0517 | 0.0096 | 0.0720 | 0.0186 | 0.8052 | 0.9427 | 0.0032 | 0.0494 | 0.0085 | 0.0247 | 0.0481 | 0.0617 | 0.1068 | 0.2099 | 0.1474 | 0.1481 | 0.1699 | 0.1728 | 0.1453 | 0.1605 | 0.1271 | 0.1111 | 0.2436 | 0.0617 | 0.0014 | 0.0026 | 0.0072 | 0.0203 | 0.0629 | 0.1090 | 0.0973 | 0.1296 | 0.5697 | 10 | 12 | 14 | 16 | 19 | 32 | 110 | 339 | 644 | 0.1456 | 63.21 | 4.433 | 0.6015 | 162507.0 | 200000000 | 303000000000 | 525000000000000 | 0.5064 | 0.1533 | 0.1318 | 0.0049 | 0.3100 | 0.0323 | 0.3324 | 0.2391 | 0.1234 | 0.2742 | 0.0561 | 0.2167 | 0.0351 | 0.1220 | 0.0042 | 0.0617 | 0.0056 | 0.0358 | 0.0014 | 0.0133 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0005 | 0.0003 | 0.0070 | 0.0065 | 0.0491 | 0.0410 | 0.0772 | 0.0740 | 0.0498 | 0.0478 | 0.0813 | 0.0702 | 0.7351 | 0.7600 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0004 | 0.0017 | 0.0119 | 0.0114 | 0.0544 | 0.0623 | 0.0908 | 0.0925 | 0.0634 | 0.0717 | 0.0934 | 0.1071 | 0.6854 | 0.6531 | 0.0000 | 0.0002 | 0.0008 | 0.0084 | 0.0511 | 0.0851 | 0.0532 | 0.0876 | 0.7136 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1215 | 861 | | 3007 | 9908 | 716.7 | 136.15 | 119.32 | 267.01 | 537 | 590 | 633 | 674 | 713 | 750 | 795 | 845 | 901 | 0.0779 | 772 | 1.131 | 79.76 | 31.58 | 2 | 0.0725 | 218 | 0.0010 | 52.74 | 7.117 | 0.1610 | 532255.0 | 408000000 | 323000000000 | 262000000000000 | 0.4330 | 0.2090 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0007 | 0.0651 | 0.0200 | 0.1481 | 0.0312 | 0.1456 | 0.0346 | 0.1792 | 0.0481 | 0.4484 | 0.8654 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0007 | 0.0316 | 0.0198 | 0.0643 | 0.0271 | 0.0583 | 0.0218 | 0.0671 | 0.0305 | 0.7723 | 0.9001 | 0.0040 | 0.0588 | 0.0059 | 0.0588 | 0.0198 | 0.0882 | 0.0931 | 0.3529 | 0.1802 | 0.2941 | 0.1842 | 0.0588 | 0.0911 | 0.0294 | 0.1564 | 0.0588 | 0.2653 | 0.0000 | 0.0000 | 0.0007 | 0.0041 | 0.0244 | 0.0807 | 0.1404 | 0.1065 | 0.1303 | 0.5129 | 7 | 9 | 10 | 11 | 13 | 16 | 31 | 132 | 393 | 0.2663 | 40.82 | 3.458 | 0.6732 | 85524.5 | 93100000 | 121000000000 | 174000000000000 | 0.6043 | 0.0864 | 0.1806 | 0.0164 | 0.2843 | 0.1228 | 0.2274 | 0.2439 | 0.1237 | 0.1735 | 0.1304 | 0.1571 | 0.0201 | 0.1489 | 0.0201 | 0.0687 | 0.0134 | 0.0491 | 0.0000 | 0.0196 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0059 | 0.0680 | 0.0675 | 0.1151 | 0.0990 | 0.0657 | 0.0671 | 0.1024 | 0.0998 | 0.6425 | 0.6607 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0115 | 0.0085 | 0.0781 | 0.0846 | 0.1289 | 0.1455 | 0.0849 | 0.0795 | 0.1226 | 0.1286 | 0.5734 | 0.5516 | 0.0000 | 0.0000 | 0.0010 | 0.0097 | 0.0711 | 0.1178 | 0.0808 | 0.1168 | 0.6027 |
| MDA-MB-231 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 986 | 375 | | 3412 | 6862 | 481.9 | 117.20 | 93.02 | 146.48 | 305 | 387 | 443 | 490 | 520 | 538 | 554 | 572 | 596 | 0.0851 | 584 | 0.932 | 72.01 | 24.21 | 1 | 0.0592 | 202 | 0.0011 | 37.12 | 7.131 | 0.2177 | 245995.0 | 130000000 | 70600000000 | 39000000000000 | 0.3975 | 0.2313 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0023 | 0.0000 | 0.0153 | 0.0006 | 0.0384 | 0.0161 | 0.0685 | 0.0274 | 0.0782 | 0.0187 | 0.1319 | 0.0332 | 0.6645 | 0.9040 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0179 | 0.0160 | 0.0285 | 0.0249 | 0.0223 | 0.0150 | 0.0347 | 0.0278 | 0.8936 | 0.9159 | 0.0209 | 0.0435 | 0.0104 | 0.0000 | 0.0330 | 0.0000 | 0.0557 | 0.0435 | 0.0783 | 0.3478 | 0.0870 | 0.1739 | 0.0991 | 0.0000 | 0.1113 | 0.3043 | 0.5043 | 0.0870 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0247 | 0.0451 | 0.0400 | 0.0679 | 0.8162 | 10 | 13 | 16 | 21 | 27 | 40 | 68 | 138 | 287 | 0.0426 | 28.93 | 4.699 | 0.5709 | 30108.0 | 15300000 | 9600000000 | 6980000000000 | 0.4972 | 0.1660 | 0.0636 | 0.0056 | 0.1051 | 0.0237 | 0.0954 | 0.0847 | 0.1345 | 0.0790 | 0.1614 | 0.0926 | 0.1809 | 0.1400 | 0.1394 | 0.1264 | 0.0831 | 0.1072 | 0.0367 | 0.3409 | 0.0005 | 0.0013 | 0.0005 | 0.0017 | 0.0036 | 0.0031 | 0.0180 | 0.0144 | 0.0598 | 0.0423 | 0.0721 | 0.0737 | 0.0562 | 0.0471 | 0.0814 | 0.0702 | 0.7079 | 0.7462 | 0.0013 | 0.0000 | 0.0020 | 0.0007 | 0.0007 | 0.0000 | 0.0196 | 0.0156 | 0.0607 | 0.0675 | 0.0881 | 0.0896 | 0.0529 | 0.0490 | 0.0783 | 0.0888 | 0.6965 | 0.6887 | 0.0012 | 0.0012 | 0.0029 | 0.0175 | 0.0544 | 0.0807 | 0.0526 | 0.0807 | 0.7089 |
| BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 442 | 641 | | 7990 | 25118 | 501.3 | 88.04 | 166.84 | 265.28 | 388 | 427 | 453 | 476 | 498 | 523 | 548 | 577 | 617 | 0.0471 | 1183 | 1.180 | 95.02 | 43.97 | 2 | 0.0333 | 266 | 0.0018 | 18.67 | 6.558 | 0.2470 | 259095.0 | 138000000 | 75200000000 | 42100000000000 | 0.4349 | 0.2174 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0004 | 0.0081 | 0.0004 | 0.0446 | 0.0106 | 0.0956 | 0.0227 | 0.1034 | 0.0182 | 0.1448 | 0.0317 | 0.6006 | 0.9161 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0003 | 0.0024 | 0.0004 | 0.0209 | 0.0097 | 0.0427 | 0.0195 | 0.0421 | 0.0112 | 0.0628 | 0.0166 | 0.8279 | 0.9424 | 0.0064 | 0.0682 | 0.0091 | 0.0455 | 0.0320 | 0.0795 | 0.0970 | 0.1591 | 0.1473 | 0.2045 | 0.1802 | 0.1591 | 0.1180 | 0.0795 | 0.1455 | 0.0909 | 0.2644 | 0.1136 | 0.0005 | 0.0038 | 0.0054 | 0.0222 | 0.0749 | 0.1073 | 0.1055 | 0.1318 | 0.5485 | 10 | 11 | 14 | 16 | 23 | 59 | 162 | 310 | 534 | 0.1363 | 42.26 | 4.688 | 0.5832 | 98205.2 | 84400000 | 91600000000 | 119000000000000 | 0.4503 | 0.1832 | 0.0986 | 0.0041 | 0.2120 | 0.0293 | 0.2896 | 0.1678 | 0.1638 | 0.1659 | 0.1033 | 0.2136 | 0.0800 | 0.1794 | 0.0287 | 0.0875 | 0.0194 | 0.0736 | 0.0047 | 0.0788 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0008 | 0.0081 | 0.0047 | 0.0452 | 0.0417 | 0.0840 | 0.0727 | 0.0594 | 0.0422 | 0.0840 | 0.0743 | 0.7185 | 0.7635 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0024 | 0.0121 | 0.0159 | 0.0604 | 0.0675 | 0.1040 | 0.1154 | 0.0752 | 0.0819 | 0.1097 | 0.1185 | 0.6378 | 0.5984 | 0.0000 | 0.0001 | 0.0012 | 0.0086 | 0.0549 | 0.0904 | 0.0693 | 0.0991 | 0.6764 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1140 | 501 | | 2795 | 5688 | 534.4 | 104.94 | 43.08 | 68.58 | 388 | 442 | 474 | 506 | 538 | 572 | 599 | 634 | 676 | 0.0939 | 534 | 0.836 | 78.23 | 21.02 | 2 | 0.0733 | 205 | 0.0014 | 24.71 | 6.757 | 0.2480 | 296615.0 | 170000000 | 100000000000 | 60500000000000 | 0.4327 | 0.2031 | 0.0000 | 0.0000 | 0.0022 | 0.0004 | 0.0017 | 0.0000 | 0.0094 | 0.0007 | 0.0409 | 0.0211 | 0.0819 | 0.0324 | 0.0658 | 0.0200 | 0.0946 | 0.0328 | 0.7035 | 0.8926 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0000 | 0.0039 | 0.0007 | 0.0215 | 0.0211 | 0.0369 | 0.0324 | 0.0292 | 0.0200 | 0.0442 | 0.0298 | 0.8638 | 0.8956 | 0.0019 | 1.0000 | 0.0058 | 0.0000 | 0.0154 | 0.0000 | 0.0288 | 0.0000 | 0.0538 | 0.0000 | 0.1019 | 0.0000 | 0.0596 | 0.0000 | 0.0904 | 0.0000 | 0.6423 | 0.0000 | 0.0021 | 0.0014 | 0.0035 | 0.0174 | 0.0306 | 0.0542 | 0.0480 | 0.0618 | 0.7811 | 3 | 4 | 6 | 7 | 9 | 16 | 32 | 74 | 139 | 0.1144 | 4.30 | 3.672 | 0.6245 | 6558.9 | 1480000 | 411000000 | 131000000000 | 0.3466 | 0.2662 | 0.0039 | 0.0100 | 0.0656 | 0.0116 | 0.1467 | 0.0282 | 0.2625 | 0.0664 | 0.2625 | 0.1678 | 0.1931 | 0.1860 | 0.0618 | 0.1794 | 0.0039 | 0.1910 | 0.0000 | 0.1595 | 0.0006 | 0.0026 | 0.0012 | 0.0037 | 0.0000 | 0.0053 | 0.0078 | 0.0100 | 0.0246 | 0.0238 | 0.0414 | 0.0365 | 0.0402 | 0.0396 | 0.0618 | 0.0497 | 0.8224 | 0.8288 | 0.0000 | 0.0000 | 0.0007 | 0.0015 | 0.0007 | 0.0008 | 0.0092 | 0.0124 | 0.0348 | 0.0372 | 0.0540 | 0.0581 | 0.0511 | 0.0550 | 0.0724 | 0.0790 | 0.7770 | 0.7560 | 0.0000 | 0.0000 | 0.0026 | 0.0059 | 0.0315 | 0.0538 | 0.0446 | 0.0649 | 0.7967 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 477 | 426 | | 5377 | 19317 | 581.1 | 160.29 | 136.17 | 209.41 | 425 | 459 | 484 | 509 | 534 | 566 | 617 | 705 | 822 | 0.0467 | 902 | 1.031 | 97.32 | 27.29 | 2 | 0.0433 | 233 | 0.0008 | 63.73 | 7.412 | 0.1708 | 363397.0 | 246000000 | 181000000000 | 144000000000000 | 0.3855 | 0.2619 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0029 | 0.0002 | 0.0165 | 0.0025 | 0.0836 | 0.0253 | 0.1454 | 0.0498 | 0.1535 | 0.0451 | 0.1707 | 0.0641 | 0.4266 | 0.8129 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0048 | 0.0002 | 0.0452 | 0.0152 | 0.0767 | 0.0238 | 0.0829 | 0.0208 | 0.1093 | 0.0315 | 0.6802 | 0.9084 | 0.0018 | 0.0000 | 0.0018 | 0.0068 | 0.0063 | 0.0068 | 0.0288 | 0.0342 | 0.0728 | 0.1182 | 0.1150 | 0.1541 | 0.0584 | 0.0908 | 0.0988 | 0.1404 | 0.6164 | 0.4486 | 0.0015 | 0.0026 | 0.0128 | 0.0271 | 0.0767 | 0.1048 | 0.0772 | 0.0905 | 0.6069 | 6 | 8 | 9 | 12 | 19 | 59 | 148 | 254 | 436 | 0.1238 | 34.07 | 4.718 | 0.5673 | 62391.7 | 40700000 | 33200000000 | 32300000000000 | 0.4255 | 0.1972 | 0.0345 | 0.0023 | 0.1373 | 0.0110 | 0.2596 | 0.0799 | 0.2092 | 0.1106 | 0.1690 | 0.2037 | 0.1018 | 0.1992 | 0.0495 | 0.1293 | 0.0271 | 0.1275 | 0.0121 | 0.1366 | 0.0003 | 0.0000 | 0.0005 | 0.0001 | 0.0009 | 0.0000 | 0.0059 | 0.0038 | 0.0367 | 0.0320 | 0.0589 | 0.0488 | 0.0443 | 0.0411 | 0.0677 | 0.0553 | 0.7847 | 0.8190 | 0.0002 | 0.0002 | 0.0002 | 0.0014 | 0.0007 | 0.0008 | 0.0100 | 0.0122 | 0.0407 | 0.0531 | 0.0851 | 0.0882 | 0.0557 | 0.0635 | 0.0838 | 0.0904 | 0.7235 | 0.6902 | 0.0000 | 0.0000 | 0.0005 | 0.0065 | 0.0403 | 0.0668 | 0.0522 | 0.0737 | 0.7600 | ||
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 779 | 704 | | 5803 | 19960 | 372.2 | 94.00 | 225.74 | 412.23 | 264 | 293 | 318 | 338 | 360 | 380 | 408 | 444 | 501 | 0.0479 | 957 | 1.184 | 131.46 | 56.92 | 1 | 0.0622 | 361 | 0.0010 | 43.53 | 7.206 | 0.1938 | 147377.0 | 62100000 | 27800000000 | 13200000000000 | 0.4343 | 0.2158 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0085 | 0.0004 | 0.0188 | 0.0023 | 0.0689 | 0.0252 | 0.1544 | 0.0502 | 0.1354 | 0.0473 | 0.1582 | 0.0622 | 0.4544 | 0.8124 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0071 | 0.0011 | 0.0331 | 0.0145 | 0.0767 | 0.0294 | 0.0663 | 0.0230 | 0.0802 | 0.0308 | 0.7347 | 0.9013 | 0.0000 | 0.0044 | 0.0062 | 0.0066 | 0.0213 | 0.0022 | 0.0364 | 0.0744 | 0.1058 | 0.1510 | 0.1538 | 0.1707 | 0.0809 | 0.1204 | 0.1200 | 0.1554 | 0.4756 | 0.3151 | 0.0020 | 0.0016 | 0.0110 | 0.0292 | 0.0817 | 0.1310 | 0.0781 | 0.1097 | 0.5558 | 8 | 10 | 11 | 13 | 15 | 26 | 121 | 400 | 845 | 0.2506 | 60.02 | 4.037 | 0.6340 | 220884.0 | 291000000 | 452000000000 | 796000000000000 | 0.4139 | 0.2037 | 0.0722 | 0.0028 | 0.2071 | 0.0270 | 0.2425 | 0.1555 | 0.1403 | 0.1634 | 0.1104 | 0.1811 | 0.0872 | 0.1783 | 0.0490 | 0.0909 | 0.0504 | 0.0831 | 0.0409 | 0.1179 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0007 | 0.0062 | 0.0044 | 0.0375 | 0.0329 | 0.0543 | 0.0543 | 0.0439 | 0.0317 | 0.0639 | 0.0529 | 0.7941 | 0.8231 | 0.0002 | 0.0000 | 0.0008 | 0.0011 | 0.0008 | 0.0013 | 0.0057 | 0.0067 | 0.0481 | 0.0528 | 0.0740 | 0.0799 | 0.0481 | 0.0528 | 0.0838 | 0.0860 | 0.7384 | 0.7192 | 0.0000 | 0.0004 | 0.0002 | 0.0082 | 0.0430 | 0.0638 | 0.0522 | 0.0724 | 0.7598 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 828 | 486 | | 14994 | 31048 | 470.7 | 84.93 | 145.23 | 202.56 | 364 | 398 | 424 | 447 | 469 | 490 | 513 | 542 | 583 | 0.0407 | 1265 | 1.143 | 89.20 | 33.84 | 2 | 0.0156 | 234 | 0.0008 | 39.09 | 7.354 | 0.1815 | 228773.0 | 115000000 | 59000000000 | 31200000000000 | 0.4389 | 0.2085 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0020 | 0.0001 | 0.0111 | 0.0005 | 0.0411 | 0.0092 | 0.0890 | 0.0204 | 0.0990 | 0.0211 | 0.1268 | 0.0342 | 0.6308 | 0.9146 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0049 | 0.0001 | 0.0183 | 0.0077 | 0.0417 | 0.0152 | 0.0417 | 0.0114 | 0.0544 | 0.0195 | 0.8381 | 0.9459 | 0.0048 | 0.0278 | 0.0077 | 0.0556 | 0.0191 | 0.1065 | 0.0689 | 0.1991 | 0.1411 | 0.2083 | 0.1689 | 0.1435 | 0.1325 | 0.0694 | 0.1536 | 0.1019 | 0.3033 | 0.0880 | 0.0004 | 0.0009 | 0.0068 | 0.0261 | 0.0682 | 0.1054 | 0.0961 | 0.1216 | 0.5745 | 6 | 8 | 10 | 13 | 30 | 83 | 171 | 296 | 457 | 0.1239 | 27.73 | 4.902 | 0.5414 | 62118.6 | 35000000 | 22900000000 | 16700000000000 | 0.4409 | 0.1994 | 0.0472 | 0.0018 | 0.1760 | 0.0086 | 0.2720 | 0.1069 | 0.1840 | 0.1494 | 0.1220 | 0.1901 | 0.0838 | 0.2070 | 0.0520 | 0.1123 | 0.0355 | 0.0968 | 0.0276 | 0.1271 | 0.0004 | 0.0000 | 0.0002 | 0.0003 | 0.0004 | 0.0005 | 0.0104 | 0.0070 | 0.0419 | 0.0383 | 0.0677 | 0.0587 | 0.0504 | 0.0418 | 0.0695 | 0.0619 | 0.7590 | 0.7915 | 0.0002 | 0.0002 | 0.0013 | 0.0006 | 0.0008 | 0.0007 | 0.0105 | 0.0168 | 0.0580 | 0.0609 | 0.0871 | 0.0932 | 0.0560 | 0.0646 | 0.0902 | 0.0922 | 0.6960 | 0.6707 | 0.0000 | 0.0003 | 0.0015 | 0.0114 | 0.0475 | 0.0781 | 0.0516 | 0.0805 | 0.7292 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 438 | 338 | | 5309 | 17377 | 254.0 | 51.30 | 154.44 | 205.30 | 192 | 208 | 222 | 236 | 250 | 263 | 278 | 296 | 323 | 0.0642 | 1116 | 0.650 | 145.45 | 37.54 | 1 | 0.0868 | 461 | 0.0009 | 54.07 | 7.276 | 0.1615 | 67165.6 | 18500000 | 5270000000 | 1560000000000 | 0.4223 | 0.2163 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0065 | 0.0004 | 0.0185 | 0.0008 | 0.0648 | 0.0167 | 0.1339 | 0.0415 | 0.1444 | 0.0348 | 0.1632 | 0.0518 | 0.4682 | 0.8540 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0000 | 0.0094 | 0.0004 | 0.0315 | 0.0125 | 0.0602 | 0.0262 | 0.0616 | 0.0142 | 0.0778 | 0.0232 | 0.7567 | 0.9236 | 0.0092 | 0.0185 | 0.0150 | 0.0139 | 0.0242 | 0.0509 | 0.0715 | 0.1667 | 0.1349 | 0.1944 | 0.1915 | 0.1944 | 0.1165 | 0.0972 | 0.1442 | 0.1065 | 0.2930 | 0.1574 | 0.0016 | 0.0032 | 0.0068 | 0.0275 | 0.0749 | 0.1247 | 0.1064 | 0.1466 | 0.5084 | 13 | 15 | 18 | 23 | 36 | 81 | 184 | 315 | 474 | 0.0496 | 33.73 | 5.257 | 0.4918 | 65995.6 | 37600000 | 25100000000 | 18900000000000 | 0.5553 | 0.1158 | 0.0613 | 0.0005 | 0.2441 | 0.0274 | 0.3613 | 0.1747 | 0.1129 | 0.1642 | 0.0914 | 0.2211 | 0.0581 | 0.1832 | 0.0280 | 0.0932 | 0.0258 | 0.0658 | 0.0172 | 0.0700 | 0.0000 | 0.0000 | 0.0005 | 0.0001 | 0.0008 | 0.0007 | 0.0082 | 0.0069 | 0.0483 | 0.0458 | 0.0858 | 0.0729 | 0.0508 | 0.0451 | 0.0837 | 0.0765 | 0.7219 | 0.7519 | 0.0002 | 0.0000 | 0.0004 | 0.0004 | 0.0008 | 0.0017 | 0.0152 | 0.0196 | 0.0552 | 0.0582 | 0.1050 | 0.1163 | 0.0616 | 0.0694 | 0.0952 | 0.0936 | 0.6664 | 0.6407 | 0.0000 | 0.0007 | 0.0011 | 0.0112 | 0.0520 | 0.0947 | 0.0605 | 0.0867 | 0.6931 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 665 | 315 | | 3881 | 7921 | 606.2 | 94.41 | 68.43 | 170.19 | 472 | 541 | 568 | 588 | 606 | 629 | 660 | 694 | 726 | 0.0917 | 726 | 0.976 | 112.07 | 42.38 | 2 | 0.0825 | 320 | 0.0014 | 32.18 | 6.910 | 0.2353 | 376420.0 | 239000000 | 154000000000 | 101000000000000 | 0.4392 | 0.1933 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0052 | 0.0005 | 0.0345 | 0.0169 | 0.0495 | 0.0301 | 0.0505 | 0.0161 | 0.0697 | 0.0270 | 0.7890 | 0.9095 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0020 | 0.0005 | 0.0212 | 0.0169 | 0.0256 | 0.0301 | 0.0206 | 0.0161 | 0.0317 | 0.0270 | 0.8986 | 0.9095 | 0.0054 | 0.0000 | 0.0161 | 0.0000 | 0.0215 | 0.0000 | 0.0538 | 0.0000 | 0.1048 | 0.0000 | 0.1532 | 0.0000 | 0.1183 | 0.0000 | 0.1263 | 0.0000 | 0.4005 | 0.0000 | 0.0031 | 0.0031 | 0.0097 | 0.0219 | 0.0429 | 0.0566 | 0.0536 | 0.0929 | 0.7163 | 5 | 6 | 7 | 9 | 10 | 11 | 14 | 30 | 209 | 0.1903 | 6.63 | 2.602 | 0.6219 | 33642.3 | 23500000 | 18600000000 | 16100000000000 | 0.5469 | 0.1234 | 0.0143 | 0.0118 | 0.2071 | 0.0059 | 0.2500 | 0.0710 | 0.2357 | 0.1154 | 0.2571 | 0.2308 | 0.0286 | 0.2337 | 0.0071 | 0.1834 | 0.0000 | 0.1065 | 0.0000 | 0.0414 | 0.0000 | 0.0021 | 0.0000 | 0.0014 | 0.0008 | 0.0050 | 0.0119 | 0.0114 | 0.0500 | 0.0456 | 0.0738 | 0.0777 | 0.0484 | 0.0428 | 0.0745 | 0.0720 | 0.7407 | 0.7418 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0009 | 0.0089 | 0.0132 | 0.0526 | 0.0545 | 0.0847 | 0.0771 | 0.0455 | 0.0526 | 0.0794 | 0.0808 | 0.7279 | 0.7209 | 0.0000 | 0.0000 | 0.0017 | 0.0093 | 0.0499 | 0.0854 | 0.0448 | 0.0761 | 0.7327 | ||
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 173 | 580 | | 3314 | 11955 | 517.2 | 91.88 | 119.57 | 243.85 | 373 | 433 | 487 | 512 | 531 | 550 | 573 | 598 | 624 | 0.0613 | 733 | 0.446 | 104.39 | 23.32 | 3 | 0.0993 | 329 | 0.0010 | 41.90 | 7.124 | 0.2030 | 275939.0 | 151000000 | 84400000000 | 48000000000000 | 0.4375 | 0.1965 | 0.0000 | 0.0000 | 0.0029 | 0.0003 | 0.0017 | 0.0003 | 0.0071 | 0.0009 | 0.0384 | 0.0163 | 0.0744 | 0.0359 | 0.0660 | 0.0157 | 0.0994 | 0.0273 | 0.7101 | 0.9033 | 0.0000 | 0.0000 | 0.0011 | 0.0003 | 0.0000 | 0.0003 | 0.0014 | 0.0009 | 0.0206 | 0.0163 | 0.0343 | 0.0359 | 0.0220 | 0.0157 | 0.0354 | 0.0273 | 0.8851 | 0.9033 | 0.0134 | 0.0000 | 0.0160 | 0.0000 | 0.0428 | 0.0000 | 0.0856 | 0.0000 | 0.1096 | 0.0000 | 0.1791 | 0.0000 | 0.1123 | 0.0000 | 0.1417 | 0.0000 | 0.2995 | 0.0000 | 0.0005 | 0.0042 | 0.0094 | 0.0141 | 0.0381 | 0.0522 | 0.0637 | 0.0914 | 0.7262 | 9 | 12 | 14 | 16 | 21 | 31 | 57 | 130 | 371 | 0.1465 | 4.98 | 3.299 | 0.6421 | 73753.8 | 72700000 | 87000000000 | 116000000000000 | 0.4905 | 0.1557 | 0.0398 | 0.0000 | 0.1155 | 0.0121 | 0.1474 | 0.0864 | 0.1932 | 0.1021 | 0.1972 | 0.1690 | 0.1554 | 0.1820 | 0.0777 | 0.1328 | 0.0498 | 0.1235 | 0.0239 | 0.1922 | 0.0000 | 0.0000 | 0.0025 | 0.0012 | 0.0051 | 0.0044 | 0.0108 | 0.0097 | 0.0375 | 0.0400 | 0.0563 | 0.0512 | 0.0512 | 0.0465 | 0.0776 | 0.0787 | 0.7589 | 0.7684 | 0.0000 | 0.0000 | 0.0004 | 0.0009 | 0.0009 | 0.0028 | 0.0119 | 0.0127 | 0.0419 | 0.0409 | 0.0608 | 0.0682 | 0.0591 | 0.0564 | 0.0784 | 0.0804 | 0.7466 | 0.7377 | 0.0008 | 0.0008 | 0.0028 | 0.0097 | 0.0399 | 0.0565 | 0.0480 | 0.0871 | 0.7543 |
| MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 420 | 742 | | 10935 | 36965 | 570.5 | 116.52 | 204.39 | 357.85 | 434 | 472 | 502 | 530 | 557 | 586 | 619 | 663 | 727 | 0.0445 | 1646 | 1.010 | 102.55 | 38.05 | 2 | 0.0258 | 282 | 0.0006 | 81.76 | 7.769 | 0.1488 | 339006.0 | 210000000 | 136000000000 | 92000000000000 | 0.4191 | 0.2288 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0035 | 0.0003 | 0.0113 | 0.0011 | 0.0543 | 0.0126 | 0.1116 | 0.0285 | 0.1155 | 0.0282 | 0.1447 | 0.0456 | 0.5584 | 0.8837 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0039 | 0.0003 | 0.0256 | 0.0086 | 0.0516 | 0.0165 | 0.0554 | 0.0121 | 0.0712 | 0.0199 | 0.7907 | 0.9426 | 0.0034 | 0.0123 | 0.0069 | 0.0369 | 0.0195 | 0.0541 | 0.0653 | 0.1253 | 0.1146 | 0.1695 | 0.1725 | 0.1892 | 0.1135 | 0.0983 | 0.1358 | 0.1007 | 0.3685 | 0.2138 | 0.0006 | 0.0044 | 0.0105 | 0.0277 | 0.0720 | 0.1148 | 0.0938 | 0.1191 | 0.5571 | 6 | 8 | 9 | 11 | 14 | 35 | 134 | 381 | 754 | 0.1781 | 65.60 | 4.468 | 0.5873 | 169829.0 | 188000000 | 243000000000 | 352000000000000 | 0.4094 | 0.2312 | 0.1194 | 0.0037 | 0.3132 | 0.0514 | 0.3248 | 0.2365 | 0.1171 | 0.2139 | 0.0620 | 0.1913 | 0.0302 | 0.1403 | 0.0225 | 0.0740 | 0.0078 | 0.0503 | 0.0031 | 0.0385 | 0.0000 | 0.0000 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0066 | 0.0033 | 0.0399 | 0.0364 | 0.0767 | 0.0693 | 0.0521 | 0.0427 | 0.0787 | 0.0708 | 0.7456 | 0.7764 | 0.0000 | 0.0000 | 0.0001 | 0.0003 | 0.0010 | 0.0015 | 0.0075 | 0.0101 | 0.0502 | 0.0538 | 0.0946 | 0.1037 | 0.0644 | 0.0702 | 0.0978 | 0.1071 | 0.6844 | 0.6533 | 0.0000 | 0.0002 | 0.0006 | 0.0068 | 0.0462 | 0.0827 | 0.0597 | 0.0911 | 0.7127 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 517 | 209 | | 10942 | 35449 | 447.3 | 110.82 | 142.08 | 205.96 | 312 | 350 | 381 | 410 | 439 | 469 | 501 | 538 | 598 | 0.0363 | 1286 | 0.903 | 94.01 | 21.02 | 3 | 0.0206 | 225 | 0.0006 | 67.31 | 7.714 | 0.1503 | 212393.0 | 107000000 | 56200000000 | 31100000000000 | 0.4346 | 0.2214 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0003 | 0.0220 | 0.0020 | 0.0807 | 0.0222 | 0.1586 | 0.0494 | 0.1521 | 0.0568 | 0.1699 | 0.0831 | 0.4104 | 0.7861 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0069 | 0.0010 | 0.0331 | 0.0142 | 0.0664 | 0.0263 | 0.0584 | 0.0248 | 0.0766 | 0.0387 | 0.7570 | 0.8948 | 0.0022 | 0.0069 | 0.0081 | 0.0139 | 0.0103 | 0.0416 | 0.0550 | 0.1150 | 0.1279 | 0.1967 | 0.1699 | 0.1884 | 0.1225 | 0.1177 | 0.1516 | 0.1399 | 0.3524 | 0.1801 | 0.0008 | 0.0008 | 0.0065 | 0.0223 | 0.0687 | 0.1106 | 0.0929 | 0.1244 | 0.5730 | 7 | 10 | 12 | 15 | 24 | 71 | 163 | 276 | 443 | 0.1042 | 31.77 | 4.906 | 0.5483 | 62607.4 | 38100000 | 28100000000 | 23900000000000 | 0.4712 | 0.1726 | 0.0362 | 0.0022 | 0.1614 | 0.0112 | 0.2304 | 0.0744 | 0.1585 | 0.1487 | 0.1473 | 0.1922 | 0.1121 | 0.1786 | 0.0662 | 0.1198 | 0.0498 | 0.1135 | 0.0382 | 0.1594 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0067 | 0.0061 | 0.0345 | 0.0311 | 0.0658 | 0.0530 | 0.0462 | 0.0389 | 0.0718 | 0.0600 | 0.7738 | 0.8102 | 0.0000 | 0.0005 | 0.0006 | 0.0007 | 0.0010 | 0.0021 | 0.0102 | 0.0107 | 0.0492 | 0.0560 | 0.0855 | 0.0946 | 0.0637 | 0.0738 | 0.0966 | 0.1019 | 0.6933 | 0.6595 | 0.0002 | 0.0003 | 0.0018 | 0.0074 | 0.0431 | 0.0740 | 0.0560 | 0.0876 | 0.7297 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1044 | 317 | | 12277 | 27737 | 337.8 | 80.82 | 126.25 | 196.68 | 245 | 268 | 287 | 306 | 326 | 349 | 374 | 406 | 447 | 0.0408 | 1133 | 1.055 | 137.89 | 53.26 | 1 | 0.0307 | 377 | 0.0011 | 31.32 | 7.089 | 0.2146 | 120627.0 | 45500000 | 18100000000 | 7610000000000 | 0.4436 | 0.2108 | 0.0003 | 0.0000 | 0.0014 | 0.0000 | 0.0075 | 0.0005 | 0.0193 | 0.0028 | 0.0768 | 0.0156 | 0.1399 | 0.0382 | 0.1395 | 0.0401 | 0.1655 | 0.0606 | 0.4499 | 0.8421 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0066 | 0.0003 | 0.0331 | 0.0088 | 0.0616 | 0.0201 | 0.0593 | 0.0159 | 0.0849 | 0.0256 | 0.7518 | 0.9293 | 0.0008 | 0.0082 | 0.0036 | 0.0192 | 0.0097 | 0.0549 | 0.0449 | 0.1152 | 0.1237 | 0.1578 | 0.1556 | 0.1852 | 0.1144 | 0.1221 | 0.1516 | 0.1221 | 0.3957 | 0.2154 | 0.0007 | 0.0024 | 0.0049 | 0.0284 | 0.0649 | 0.1105 | 0.0822 | 0.1107 | 0.5952 | 5 | 7 | 8 | 10 | 13 | 46 | 142 | 252 | 404 | 0.0900 | 13.02 | 4.139 | 0.4903 | 54618.6 | 33500000 | 26000000000 | 23800000000000 | 0.3964 | 0.2554 | 0.0519 | 0.0030 | 0.2024 | 0.0144 | 0.3281 | 0.0926 | 0.1490 | 0.1590 | 0.1211 | 0.2328 | 0.0760 | 0.2176 | 0.0384 | 0.1206 | 0.0256 | 0.0893 | 0.0075 | 0.0708 | 0.0000 | 0.0000 | 0.0002 | 0.0003 | 0.0009 | 0.0006 | 0.0045 | 0.0028 | 0.0333 | 0.0259 | 0.0610 | 0.0514 | 0.0479 | 0.0383 | 0.0731 | 0.0617 | 0.7792 | 0.8190 | 0.0002 | 0.0001 | 0.0001 | 0.0012 | 0.0011 | 0.0016 | 0.0074 | 0.0108 | 0.0452 | 0.0500 | 0.0802 | 0.0994 | 0.0683 | 0.0688 | 0.0954 | 0.1041 | 0.7019 | 0.6639 | 0.0001 | 0.0001 | 0.0005 | 0.0061 | 0.0373 | 0.0712 | 0.0564 | 0.0847 | 0.7437 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 727 | | 435 | 10158 | 216.6 | 37.95 | 134.54 | 228.49 | 169 | 184 | 193 | 205 | 215 | 223 | 235 | 249 | 268 | 0.0475 | 483 | 1.039 | 156.49 | 50.48 | 1 | 0.9218 | 401 | 0.0052 | 14.90 | 5.415 | 0.3014 | 48369.5 | 11100000 | 2630000000 | 636000000000 | 0.4349 | 0.2080 | 0.0000 | 0.0000 | 0.0096 | 0.0000 | 0.0096 | 0.0000 | 0.0382 | 0.0047 | 0.1019 | 0.0606 | 0.1656 | 0.0629 | 0.1624 | 0.0606 | 0.1943 | 0.0956 | 0.3185 | 0.7156 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0186 | 0.0023 | 0.0849 | 0.0621 | 0.1088 | 0.0552 | 0.0928 | 0.0437 | 0.1432 | 0.0759 | 0.5517 | 0.7609 | 0.0000 | 0.1667 | 0.0000 | 0.0000 | 0.0635 | 0.1667 | 0.1905 | 0.3333 | 0.1429 | 0.3333 | 0.2540 | 0.0000 | 0.1270 | 0.0000 | 0.0635 | 0.0000 | 0.1587 | 0.0000 | 0.0000 | 0.0095 | 0.0237 | 0.0616 | 0.1754 | 0.1469 | 0.1280 | 0.1801 | 0.2749 | 5 | 7 | 8 | 9 | 11 | 16 | 98 | 264 | 495 | 0.1308 | 20.25 | 3.815 | 0.5357 | 70302.5 | 49000000 | 40900000000 | 40000000000000 | 0.5326 | 0.1283 | 0.0600 | 0.0028 | 0.2086 | 0.0308 | 0.2229 | 0.1413 | 0.2086 | 0.1636 | 0.1400 | 0.2070 | 0.0686 | 0.1930 | 0.0514 | 0.1035 | 0.0371 | 0.0867 | 0.0029 | 0.0713 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0047 | 0.0269 | 0.0233 | 0.0561 | 0.0472 | 0.0326 | 0.0315 | 0.0668 | 0.0585 | 0.8136 | 0.8348 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0011 | 0.0020 | 0.0049 | 0.0053 | 0.0377 | 0.0422 | 0.0681 | 0.0763 | 0.0518 | 0.0666 | 0.0883 | 0.0849 | 0.7477 | 0.7223 | 0.0000 | 0.0000 | 0.0011 | 0.0029 | 0.0350 | 0.0622 | 0.0404 | 0.0733 | 0.7851 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1106 | 397 | | 3909 | 8740 | 289.1 | 95.66 | 91.54 | 172.00 | 154 | 205 | 243 | 269 | 293 | 316 | 338 | 365 | 406 | 0.0800 | 699 | 0.961 | 103.76 | 31.24 | 5 | 0.0686 | 268 | 0.0009 | 36.10 | 7.234 | 0.1915 | 92721.2 | 32200000 | 11900000000 | 4700000000000 | 0.3747 | 0.2534 | 0.0005 | 0.0000 | 0.0022 | 0.0000 | 0.0027 | 0.0020 | 0.0142 | 0.0044 | 0.0650 | 0.0282 | 0.1301 | 0.0493 | 0.1055 | 0.0413 | 0.1301 | 0.0577 | 0.5497 | 0.8172 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0009 | 0.0021 | 0.0024 | 0.0202 | 0.0172 | 0.0401 | 0.0237 | 0.0262 | 0.0181 | 0.0391 | 0.0255 | 0.8713 | 0.9124 | 0.0010 | 0.0050 | 0.0048 | 0.0000 | 0.0096 | 0.0201 | 0.0231 | 0.0352 | 0.0723 | 0.0754 | 0.1070 | 0.1583 | 0.0762 | 0.0829 | 0.1022 | 0.1231 | 0.6037 | 0.5000 | 0.0000 | 0.0005 | 0.0015 | 0.0098 | 0.0403 | 0.0811 | 0.0546 | 0.0728 | 0.7394 | 6 | 7 | 9 | 11 | 15 | 29 | 59 | 122 | 279 | 0.1076 | 18.25 | 4.063 | 0.6042 | 37960.0 | 23800000 | 17700000000 | 14700000000000 | 0.5729 | 0.1131 | 0.0104 | 0.0020 | 0.0849 | 0.0088 | 0.1594 | 0.0344 | 0.1946 | 0.0698 | 0.2070 | 0.1740 | 0.1698 | 0.1878 | 0.0787 | 0.1593 | 0.0600 | 0.1524 | 0.0352 | 0.2114 | 0.0004 | 0.0004 | 0.0026 | 0.0015 | 0.0030 | 0.0037 | 0.0159 | 0.0089 | 0.0434 | 0.0426 | 0.0606 | 0.0600 | 0.0585 | 0.0474 | 0.0912 | 0.0803 | 0.7243 | 0.7553 | 0.0000 | 0.0006 | 0.0038 | 0.0012 | 0.0011 | 0.0036 | 0.0125 | 0.0119 | 0.0554 | 0.0641 | 0.0760 | 0.0766 | 0.0662 | 0.0719 | 0.0928 | 0.1021 | 0.6922 | 0.6681 | 0.0005 | 0.0024 | 0.0049 | 0.0093 | 0.0480 | 0.0720 | 0.0587 | 0.0896 | 0.7146 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 525 | 784 | | 306 | 3162 | 64.0 | 11.66 | 117.65 | 178.73 | 49 | 52 | 58 | 61 | 64 | 67 | 70 | 74 | 79 | 0.1395 | 441 | 1.153 | 68.73 | 23.77 | 1 | 0.5556 | 170 | 0.0077 | 10.17 | 5.047 | 0.3110 | 4226.0 | 287862 | 20200000 | 1450000000 | 0.4562 | 0.1761 | 0.0000 | 0.0000 | 0.0147 | 0.0033 | 0.0196 | 0.0000 | 0.0686 | 0.0133 | 0.1520 | 0.0365 | 0.1765 | 0.1794 | 0.1520 | 0.0332 | 0.1912 | 0.1296 | 0.2255 | 0.6047 | 0.0000 | 0.0000 | 0.0118 | 0.0033 | 0.0039 | 0.0000 | 0.0433 | 0.0131 | 0.0630 | 0.0359 | 0.1299 | 0.1634 | 0.0591 | 0.0327 | 0.1378 | 0.0882 | 0.5512 | 0.6634 | 0.0400 | 0.0000 | 0.0000 | 0.0000 | 0.0800 | 0.0000 | 0.0600 | 0.8000 | 0.2200 | 0.2000 | 0.2000 | 0.0000 | 0.1400 | 0.0000 | 0.1400 | 0.0000 | 0.1200 | 0.0000 | 0.0062 | 0.0124 | 0.0248 | 0.0559 | 0.1242 | 0.0994 | 0.1242 | 0.1180 | 0.4348 | 11 | 12 | 13 | 15 | 18 | 44 | 106 | 220 | 400 | 0.1851 | 37.34 | 4.002 | 0.6018 | 45776.0 | 25200000 | 16900000000 | 13200000000000 | 0.6720 | 0.0567 | 0.1282 | 0.0081 | 0.1949 | 0.0782 | 0.2513 | 0.1240 | 0.1179 | 0.1563 | 0.1128 | 0.1725 | 0.0667 | 0.1590 | 0.0359 | 0.0755 | 0.0359 | 0.0916 | 0.0564 | 0.1348 | 0.0010 | 0.0000 | 0.0010 | 0.0009 | 0.0040 | 0.0027 | 0.0210 | 0.0153 | 0.0791 | 0.0694 | 0.1351 | 0.1127 | 0.1011 | 0.0902 | 0.1592 | 0.1461 | 0.4985 | 0.5627 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0012 | 0.0054 | 0.0348 | 0.0312 | 0.1057 | 0.1098 | 0.1480 | 0.1707 | 0.1294 | 0.1328 | 0.1654 | 0.1667 | 0.4142 | 0.3821 | 0.0011 | 0.0000 | 0.0033 | 0.0255 | 0.0909 | 0.1408 | 0.1098 | 0.1663 | 0.4623 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 835 | 668 | | 9436 | 26949 | 509.0 | 119.52 | 167.87 | 203.60 | 373 | 412 | 441 | 467 | 495 | 522 | 555 | 598 | 668 | 0.0413 | 1112 | 0.662 | 166.43 | 45.61 | 1 | 0.0520 | 491 | 0.0006 | 62.28 | 7.676 | 0.1552 | 273329.0 | 155000000 | 92900000000 | 58900000000000 | 0.4414 | 0.2158 | 0.0005 | 0.0000 | 0.0010 | 0.0001 | 0.0045 | 0.0001 | 0.0160 | 0.0016 | 0.0599 | 0.0173 | 0.1253 | 0.0382 | 0.1333 | 0.0410 | 0.1696 | 0.0533 | 0.4898 | 0.8484 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0056 | 0.0004 | 0.0284 | 0.0114 | 0.0665 | 0.0214 | 0.0584 | 0.0205 | 0.0867 | 0.0273 | 0.7535 | 0.9190 | 0.0030 | 0.0000 | 0.0095 | 0.0141 | 0.0233 | 0.0194 | 0.0531 | 0.0952 | 0.1103 | 0.1411 | 0.1455 | 0.1711 | 0.0960 | 0.0935 | 0.1306 | 0.1323 | 0.4287 | 0.3333 | 0.0002 | 0.0045 | 0.0079 | 0.0271 | 0.0857 | 0.1202 | 0.0911 | 0.1114 | 0.5519 | 8 | 11 | 17 | 36 | 77 | 141 | 218 | 316 | 466 | 0.0551 | 40.07 | 5.701 | 0.4557 | 69631.7 | 39300000 | 26800000000 | 21000000000000 | 0.4485 | 0.1832 | 0.0434 | 0.0008 | 0.1902 | 0.0126 | 0.2802 | 0.1166 | 0.1517 | 0.1613 | 0.1292 | 0.2019 | 0.0888 | 0.1955 | 0.0589 | 0.1175 | 0.0323 | 0.0958 | 0.0254 | 0.0979 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0093 | 0.0067 | 0.0549 | 0.0483 | 0.1006 | 0.0833 | 0.0610 | 0.0527 | 0.0967 | 0.0874 | 0.6773 | 0.7214 | 0.0002 | 0.0004 | 0.0009 | 0.0003 | 0.0012 | 0.0017 | 0.0175 | 0.0227 | 0.0800 | 0.0909 | 0.1203 | 0.1382 | 0.0793 | 0.0819 | 0.1150 | 0.1299 | 0.5857 | 0.5341 | 0.0000 | 0.0002 | 0.0021 | 0.0123 | 0.0723 | 0.1039 | 0.0750 | 0.1098 | 0.6245 |