High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1205 | 176 | 372 | 2800 | 40.2 | 10.05 | 84.88 | 173.91 | 28 | 30 | 34 | 37 | 39 | 41 | 45 | 49 | 53 | 0.1139 | 319 | 0.581 | 191.64 | 52.00 | 2 | 1.5618 | 581 | 0.0086 | 8.20 | 4.933 | 0.3440 | 1713.9 | 77670.5 | 3730000 | 189000000 | 0.3953 | 0.2248 | 0.0051 | 0.0000 | 0.0154 | 0.0000 | 0.0359 | 0.0000 | 0.1333 | 0.0088 | 0.1744 | 0.0821 | 0.1897 | 0.0645 | 0.2154 | 0.1026 | 0.1333 | 0.1378 | 0.0974 | 0.6041 | 0.0036 | 0.0000 | 0.0108 | 0.0000 | 0.0108 | 0.0000 | 0.0502 | 0.0054 | 0.0681 | 0.0622 | 0.0681 | 0.0514 | 0.0968 | 0.0514 | 0.1147 | 0.0784 | 0.5771 | 0.7514 | 0.0000 | 0.0000 | 0.0357 | 0.0345 | 0.1190 | 0.0690 | 0.0238 | 0.2069 | 0.1786 | 0.1379 | 0.1667 | 0.0345 | 0.0952 | 0.2069 | 0.1548 | 0.1379 | 0.2262 | 0.1724 | 0.0056 | 0.0056 | 0.0222 | 0.0444 | 0.0778 | 0.0944 | 0.0889 | 0.1778 | 0.4833 | 15 | 17 | 19 | 21 | 23 | 27 | 32 | 79 | 241 | 0.2089 | 3.35 | 2.782 | 0.7521 | 37440.5 | 29600000 | 28700000000 | 30700000000000 | 0.7152 | 0.0493 | 0.0130 | 0.0061 | 0.1299 | 0.0242 | 0.2987 | 0.0242 | 0.1948 | 0.0848 | 0.1429 | 0.2061 | 0.0779 | 0.2485 | 0.0649 | 0.1333 | 0.0260 | 0.1455 | 0.0519 | 0.1273 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0047 | 0.0120 | 0.0126 | 0.0342 | 0.0346 | 0.0496 | 0.0362 | 0.0479 | 0.0472 | 0.0803 | 0.0849 | 0.7761 | 0.7799 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0039 | 0.0021 | 0.0138 | 0.0085 | 0.0472 | 0.0446 | 0.0591 | 0.0807 | 0.0571 | 0.0573 | 0.1004 | 0.1083 | 0.7185 | 0.6985 | 0.0000 | 0.0000 | 0.0018 | 0.0091 | 0.0453 | 0.0507 | 0.0562 | 0.0888 | 0.7482 | |
MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 779 | 704 | 5803 | 19960 | 372.2 | 94.00 | 225.74 | 412.23 | 264 | 293 | 318 | 338 | 360 | 380 | 408 | 444 | 501 | 0.0479 | 957 | 1.184 | 131.46 | 56.92 | 1 | 0.0622 | 361 | 0.0010 | 43.53 | 7.206 | 0.1938 | 147377.0 | 62100000 | 27800000000 | 13200000000000 | 0.4343 | 0.2158 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0085 | 0.0004 | 0.0188 | 0.0023 | 0.0689 | 0.0252 | 0.1544 | 0.0502 | 0.1354 | 0.0473 | 0.1582 | 0.0622 | 0.4544 | 0.8124 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0015 | 0.0000 | 0.0071 | 0.0011 | 0.0331 | 0.0145 | 0.0767 | 0.0294 | 0.0663 | 0.0230 | 0.0802 | 0.0308 | 0.7347 | 0.9013 | 0.0000 | 0.0044 | 0.0062 | 0.0066 | 0.0213 | 0.0022 | 0.0364 | 0.0744 | 0.1058 | 0.1510 | 0.1538 | 0.1707 | 0.0809 | 0.1204 | 0.1200 | 0.1554 | 0.4756 | 0.3151 | 0.0020 | 0.0016 | 0.0110 | 0.0292 | 0.0817 | 0.1310 | 0.0781 | 0.1097 | 0.5558 | 8 | 10 | 11 | 13 | 15 | 26 | 121 | 400 | 845 | 0.2506 | 60.02 | 4.037 | 0.6340 | 220884.0 | 291000000 | 452000000000 | 796000000000000 | 0.4139 | 0.2037 | 0.0722 | 0.0028 | 0.2071 | 0.0270 | 0.2425 | 0.1555 | 0.1403 | 0.1634 | 0.1104 | 0.1811 | 0.0872 | 0.1783 | 0.0490 | 0.0909 | 0.0504 | 0.0831 | 0.0409 | 0.1179 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0007 | 0.0062 | 0.0044 | 0.0375 | 0.0329 | 0.0543 | 0.0543 | 0.0439 | 0.0317 | 0.0639 | 0.0529 | 0.7941 | 0.8231 | 0.0002 | 0.0000 | 0.0008 | 0.0011 | 0.0008 | 0.0013 | 0.0057 | 0.0067 | 0.0481 | 0.0528 | 0.0740 | 0.0799 | 0.0481 | 0.0528 | 0.0838 | 0.0860 | 0.7384 | 0.7192 | 0.0000 | 0.0004 | 0.0002 | 0.0082 | 0.0430 | 0.0638 | 0.0522 | 0.0724 | 0.7598 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1217 | 492 | 4158 | 8748 | 478.3 | 77.87 | 112.81 | 236.09 | 376 | 414 | 441 | 464 | 483 | 499 | 516 | 535 | 574 | 0.0725 | 634 | 0.983 | 79.31 | 27.31 | 1 | 0.0536 | 223 | 0.0016 | 22.49 | 6.757 | 0.2408 | 234837.0 | 118000000 | 60800000000 | 31900000000000 | 0.3975 | 0.2479 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0000 | 0.0070 | 0.0005 | 0.0263 | 0.0161 | 0.0444 | 0.0266 | 0.0456 | 0.0159 | 0.0702 | 0.0242 | 0.8058 | 0.9168 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0002 | 0.0174 | 0.0145 | 0.0277 | 0.0252 | 0.0261 | 0.0128 | 0.0397 | 0.0206 | 0.8859 | 0.9267 | 0.0048 | 0.0000 | 0.0048 | 0.0000 | 0.0096 | 0.0556 | 0.0264 | 0.0833 | 0.0769 | 0.1667 | 0.0817 | 0.1389 | 0.1082 | 0.1667 | 0.1034 | 0.1111 | 0.5841 | 0.2778 | 0.0014 | 0.0018 | 0.0063 | 0.0136 | 0.0407 | 0.0678 | 0.0691 | 0.0985 | 0.7010 | 5 | 7 | 8 | 9 | 10 | 12 | 22 | 146 | 413 | 0.1638 | 17.76 | 3.315 | 0.5824 | 68457.9 | 58700000 | 59900000000 | 68200000000000 | 0.3262 | 0.2943 | 0.0588 | 0.0025 | 0.2888 | 0.0296 | 0.2513 | 0.1605 | 0.1016 | 0.1951 | 0.1123 | 0.1975 | 0.0695 | 0.1383 | 0.1016 | 0.0864 | 0.0107 | 0.0963 | 0.0053 | 0.0938 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0005 | 0.0081 | 0.0076 | 0.0389 | 0.0360 | 0.0567 | 0.0536 | 0.0354 | 0.0337 | 0.0445 | 0.0469 | 0.8164 | 0.8208 | 0.0006 | 0.0006 | 0.0000 | 0.0012 | 0.0045 | 0.0041 | 0.0078 | 0.0088 | 0.0380 | 0.0364 | 0.0553 | 0.0634 | 0.0330 | 0.0346 | 0.0508 | 0.0511 | 0.8101 | 0.7999 | 0.0000 | 0.0000 | 0.0005 | 0.0123 | 0.0410 | 0.0511 | 0.0373 | 0.0453 | 0.8125 | |||
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1215 | 861 | 3007 | 9908 | 716.7 | 136.15 | 119.32 | 267.01 | 537 | 590 | 633 | 674 | 713 | 750 | 795 | 845 | 901 | 0.0779 | 772 | 1.131 | 79.76 | 31.58 | 2 | 0.0725 | 218 | 0.0010 | 52.74 | 7.117 | 0.1610 | 532255.0 | 408000000 | 323000000000 | 262000000000000 | 0.4330 | 0.2090 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0000 | 0.0000 | 0.0125 | 0.0007 | 0.0651 | 0.0200 | 0.1481 | 0.0312 | 0.1456 | 0.0346 | 0.1792 | 0.0481 | 0.4484 | 0.8654 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0007 | 0.0316 | 0.0198 | 0.0643 | 0.0271 | 0.0583 | 0.0218 | 0.0671 | 0.0305 | 0.7723 | 0.9001 | 0.0040 | 0.0588 | 0.0059 | 0.0588 | 0.0198 | 0.0882 | 0.0931 | 0.3529 | 0.1802 | 0.2941 | 0.1842 | 0.0588 | 0.0911 | 0.0294 | 0.1564 | 0.0588 | 0.2653 | 0.0000 | 0.0000 | 0.0007 | 0.0041 | 0.0244 | 0.0807 | 0.1404 | 0.1065 | 0.1303 | 0.5129 | 7 | 9 | 10 | 11 | 13 | 16 | 31 | 132 | 393 | 0.2663 | 40.82 | 3.458 | 0.6732 | 85524.5 | 93100000 | 121000000000 | 174000000000000 | 0.6043 | 0.0864 | 0.1806 | 0.0164 | 0.2843 | 0.1228 | 0.2274 | 0.2439 | 0.1237 | 0.1735 | 0.1304 | 0.1571 | 0.0201 | 0.1489 | 0.0201 | 0.0687 | 0.0134 | 0.0491 | 0.0000 | 0.0196 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0063 | 0.0059 | 0.0680 | 0.0675 | 0.1151 | 0.0990 | 0.0657 | 0.0671 | 0.1024 | 0.0998 | 0.6425 | 0.6607 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0115 | 0.0085 | 0.0781 | 0.0846 | 0.1289 | 0.1455 | 0.0849 | 0.0795 | 0.1226 | 0.1286 | 0.5734 | 0.5516 | 0.0000 | 0.0000 | 0.0010 | 0.0097 | 0.0711 | 0.1178 | 0.0808 | 0.1168 | 0.6027 | |
MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1140 | 501 | 2795 | 5688 | 534.4 | 104.94 | 43.08 | 68.58 | 388 | 442 | 474 | 506 | 538 | 572 | 599 | 634 | 676 | 0.0939 | 534 | 0.836 | 78.23 | 21.02 | 2 | 0.0733 | 205 | 0.0014 | 24.71 | 6.757 | 0.2480 | 296615.0 | 170000000 | 100000000000 | 60500000000000 | 0.4327 | 0.2031 | 0.0000 | 0.0000 | 0.0022 | 0.0004 | 0.0017 | 0.0000 | 0.0094 | 0.0007 | 0.0409 | 0.0211 | 0.0819 | 0.0324 | 0.0658 | 0.0200 | 0.0946 | 0.0328 | 0.7035 | 0.8926 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0000 | 0.0039 | 0.0007 | 0.0215 | 0.0211 | 0.0369 | 0.0324 | 0.0292 | 0.0200 | 0.0442 | 0.0298 | 0.8638 | 0.8956 | 0.0019 | 1.0000 | 0.0058 | 0.0000 | 0.0154 | 0.0000 | 0.0288 | 0.0000 | 0.0538 | 0.0000 | 0.1019 | 0.0000 | 0.0596 | 0.0000 | 0.0904 | 0.0000 | 0.6423 | 0.0000 | 0.0021 | 0.0014 | 0.0035 | 0.0174 | 0.0306 | 0.0542 | 0.0480 | 0.0618 | 0.7811 | 3 | 4 | 6 | 7 | 9 | 16 | 32 | 74 | 139 | 0.1144 | 4.30 | 3.672 | 0.6245 | 6558.9 | 1480000 | 411000000 | 131000000000 | 0.3466 | 0.2662 | 0.0039 | 0.0100 | 0.0656 | 0.0116 | 0.1467 | 0.0282 | 0.2625 | 0.0664 | 0.2625 | 0.1678 | 0.1931 | 0.1860 | 0.0618 | 0.1794 | 0.0039 | 0.1910 | 0.0000 | 0.1595 | 0.0006 | 0.0026 | 0.0012 | 0.0037 | 0.0000 | 0.0053 | 0.0078 | 0.0100 | 0.0246 | 0.0238 | 0.0414 | 0.0365 | 0.0402 | 0.0396 | 0.0618 | 0.0497 | 0.8224 | 0.8288 | 0.0000 | 0.0000 | 0.0007 | 0.0015 | 0.0007 | 0.0008 | 0.0092 | 0.0124 | 0.0348 | 0.0372 | 0.0540 | 0.0581 | 0.0511 | 0.0550 | 0.0724 | 0.0790 | 0.7770 | 0.7560 | 0.0000 | 0.0000 | 0.0026 | 0.0059 | 0.0315 | 0.0538 | 0.0446 | 0.0649 | 0.7967 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1164 | 748 | 6717 | 22463 | 231.2 | 47.47 | 136.57 | 200.73 | 173 | 191 | 204 | 215 | 227 | 239 | 252 | 268 | 296 | 0.0526 | 1181 | 0.934 | 159.62 | 41.01 | 1 | 0.0582 | 391 | 0.0009 | 55.53 | 7.264 | 0.1600 | 55703.1 | 14000000 | 3650000000 | 990000000000 | 0.4604 | 0.1920 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0003 | 0.0127 | 0.0008 | 0.0689 | 0.0184 | 0.1261 | 0.0348 | 0.1510 | 0.0342 | 0.1834 | 0.0606 | 0.4552 | 0.8508 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0001 | 0.0050 | 0.0003 | 0.0314 | 0.0132 | 0.0557 | 0.0204 | 0.0683 | 0.0150 | 0.0944 | 0.0288 | 0.7437 | 0.9222 | 0.0094 | 0.0220 | 0.0122 | 0.0293 | 0.0300 | 0.0549 | 0.0880 | 0.1172 | 0.1451 | 0.2125 | 0.1751 | 0.1978 | 0.1170 | 0.1026 | 0.1517 | 0.1172 | 0.2715 | 0.1465 | 0.0006 | 0.0029 | 0.0095 | 0.0350 | 0.1008 | 0.1316 | 0.1272 | 0.1459 | 0.4464 | 8 | 10 | 11 | 13 | 17 | 50 | 153 | 289 | 440 | 0.1678 | 32.49 | 4.522 | 0.5734 | 58941.1 | 34500000 | 24900000000 | 22000000000000 | 0.4912 | 0.1551 | 0.1222 | 0.0039 | 0.3163 | 0.0380 | 0.3182 | 0.2866 | 0.1251 | 0.2349 | 0.0660 | 0.1696 | 0.0394 | 0.1194 | 0.0089 | 0.0653 | 0.0039 | 0.0443 | 0.0000 | 0.0380 | 0.0000 | 0.0000 | 0.0005 | 0.0001 | 0.0001 | 0.0002 | 0.0044 | 0.0063 | 0.0495 | 0.0387 | 0.0788 | 0.0683 | 0.0580 | 0.0512 | 0.1014 | 0.0836 | 0.7073 | 0.7515 | 0.0000 | 0.0003 | 0.0003 | 0.0005 | 0.0002 | 0.0016 | 0.0104 | 0.0097 | 0.0555 | 0.0675 | 0.1057 | 0.1099 | 0.0760 | 0.0890 | 0.1243 | 0.1280 | 0.6276 | 0.5934 | 0.0000 | 0.0006 | 0.0006 | 0.0083 | 0.0528 | 0.0884 | 0.0720 | 0.1141 | 0.6632 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 936 | 824 | 6449 | 21481 | 423.4 | 94.11 | 65.04 | 80.19 | 317 | 342 | 363 | 384 | 406 | 430 | 462 | 503 | 558 | 0.0487 | 1047 | 0.994 | 112.45 | 43.42 | 1 | 0.0482 | 311 | 0.0009 | 45.87 | 7.285 | 0.1707 | 188113.0 | 87800000 | 42900000000 | 22000000000000 | 0.4226 | 0.2238 | 0.0002 | 0.0000 | 0.0005 | 0.0002 | 0.0027 | 0.0002 | 0.0178 | 0.0020 | 0.0677 | 0.0179 | 0.1322 | 0.0358 | 0.1404 | 0.0349 | 0.1777 | 0.0545 | 0.4607 | 0.8547 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0066 | 0.0000 | 0.0301 | 0.0114 | 0.0587 | 0.0202 | 0.0584 | 0.0129 | 0.0904 | 0.0227 | 0.7539 | 0.9328 | 0.0032 | 0.0026 | 0.0097 | 0.0129 | 0.0130 | 0.0206 | 0.0536 | 0.0851 | 0.1218 | 0.2010 | 0.1404 | 0.1469 | 0.1055 | 0.1392 | 0.1502 | 0.1624 | 0.4026 | 0.2294 | 0.0011 | 0.0054 | 0.0058 | 0.0307 | 0.0719 | 0.1135 | 0.0973 | 0.1135 | 0.5607 | 6 | 8 | 10 | 14 | 26 | 50 | 85 | 121 | 172 | 0.0959 | 7.90 | 4.467 | 0.5774 | 10661.1 | 2560000 | 795000000 | 304000000000 | 0.4718 | 0.1706 | 0.0377 | 0.0018 | 0.1636 | 0.0076 | 0.2796 | 0.0566 | 0.1975 | 0.1401 | 0.1494 | 0.2175 | 0.0821 | 0.2166 | 0.0488 | 0.1351 | 0.0309 | 0.1061 | 0.0105 | 0.1187 | 0.0006 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0077 | 0.0074 | 0.0426 | 0.0363 | 0.0686 | 0.0582 | 0.0524 | 0.0451 | 0.0781 | 0.0670 | 0.7499 | 0.7845 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0019 | 0.0030 | 0.0108 | 0.0165 | 0.0583 | 0.0629 | 0.0853 | 0.0985 | 0.0701 | 0.0795 | 0.1004 | 0.1112 | 0.6732 | 0.6271 | 0.0000 | 0.0001 | 0.0014 | 0.0094 | 0.0487 | 0.0799 | 0.0555 | 0.0843 | 0.7206 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1069 | 181 | 1596 | 20629 | 124.5 | 28.67 | 72.87 | 146.49 | 98 | 102 | 107 | 111 | 116 | 122 | 130 | 143 | 162 | 0.0438 | 904 | 0.809 | 207.96 | 60.42 | 1 | 0.3440 | 549 | 0.0093 | 6.72 | 5.134 | 0.4357 | 16321.0 | 2270000 | 339000000 | 54100000000 | 0.4382 | 0.2050 | 0.0064 | 0.0000 | 0.0064 | 0.0000 | 0.0091 | 0.0000 | 0.0246 | 0.0027 | 0.0665 | 0.0317 | 0.0938 | 0.0661 | 0.1084 | 0.0465 | 0.1321 | 0.0715 | 0.5528 | 0.7815 | 0.0051 | 0.0000 | 0.0044 | 0.0000 | 0.0066 | 0.0000 | 0.0139 | 0.0025 | 0.0285 | 0.0257 | 0.0446 | 0.0426 | 0.0599 | 0.0238 | 0.0833 | 0.0401 | 0.7538 | 0.8653 | 0.0000 | 0.0000 | 0.0037 | 0.0000 | 0.0111 | 0.0000 | 0.0406 | 0.0000 | 0.1144 | 0.0000 | 0.1476 | 0.0000 | 0.1144 | 0.0000 | 0.1255 | 0.0000 | 0.4428 | 0.0000 | 0.0016 | 0.0081 | 0.0049 | 0.0357 | 0.0535 | 0.1086 | 0.0729 | 0.1135 | 0.6013 | 7 | 9 | 11 | 12 | 13 | 15 | 19 | 61 | 281 | 0.2995 | 21.07 | 3.063 | 0.7088 | 26767.6 | 14200000 | 8950000000 | 6390000000000 | 0.3754 | 0.2426 | 0.1380 | 0.0048 | 0.3646 | 0.0530 | 0.2760 | 0.2133 | 0.1250 | 0.2337 | 0.0781 | 0.2422 | 0.0156 | 0.1627 | 0.0026 | 0.0590 | 0.0000 | 0.0217 | 0.0000 | 0.0096 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0002 | 0.0005 | 0.0062 | 0.0050 | 0.0345 | 0.0311 | 0.0536 | 0.0493 | 0.0409 | 0.0369 | 0.0551 | 0.0516 | 0.8092 | 0.8256 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0018 | 0.0030 | 0.0082 | 0.0075 | 0.0356 | 0.0413 | 0.0757 | 0.0865 | 0.0522 | 0.0543 | 0.0707 | 0.0848 | 0.7559 | 0.7221 | 0.0000 | 0.0003 | 0.0008 | 0.0058 | 0.0340 | 0.0678 | 0.0421 | 0.0646 | 0.7846 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 948 | 602 | 5482 | 6626 | 431.8 | 96.54 | 133.95 | 147.02 | 321 | 351 | 372 | 394 | 415 | 441 | 472 | 515 | 567 | 0.1180 | 782 | 1.222 | 113.85 | 42.45 | 1 | 0.0520 | 285 | 0.0009 | 43.04 | 7.265 | 0.1744 | 195782.0 | 93200000 | 46500000000 | 24300000000000 | 0.4072 | 0.2460 | 0.0012 | 0.0000 | 0.0006 | 0.0000 | 0.0035 | 0.0000 | 0.0145 | 0.0012 | 0.0707 | 0.0208 | 0.1385 | 0.0387 | 0.1405 | 0.0363 | 0.1657 | 0.0562 | 0.4649 | 0.8469 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0056 | 0.0004 | 0.0357 | 0.0158 | 0.0655 | 0.0214 | 0.0748 | 0.0204 | 0.0919 | 0.0339 | 0.7240 | 0.9081 | 0.0029 | 0.0035 | 0.0029 | 0.0035 | 0.0095 | 0.0141 | 0.0475 | 0.0742 | 0.0846 | 0.1696 | 0.1454 | 0.2155 | 0.1055 | 0.1060 | 0.1084 | 0.1095 | 0.4933 | 0.3039 | 0.0021 | 0.0008 | 0.0119 | 0.0296 | 0.0716 | 0.1067 | 0.0809 | 0.0949 | 0.6014 | 11 | 15 | 23 | 44 | 79 | 120 | 169 | 238 | 356 | 0.0197 | 24.70 | 5.729 | 0.4245 | 39552.5 | 16000000 | 7850000000 | 4460000000000 | 0.4462 | 0.1848 | 0.0329 | 0.0007 | 0.1368 | 0.0059 | 0.2053 | 0.0553 | 0.2026 | 0.1211 | 0.1539 | 0.1895 | 0.1250 | 0.1914 | 0.0645 | 0.1303 | 0.0500 | 0.1375 | 0.0289 | 0.1684 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0012 | 0.0119 | 0.0055 | 0.0633 | 0.0525 | 0.0857 | 0.0756 | 0.0689 | 0.0619 | 0.1147 | 0.1026 | 0.6548 | 0.7008 | 0.0010 | 0.0017 | 0.0010 | 0.0017 | 0.0048 | 0.0039 | 0.0162 | 0.0231 | 0.0796 | 0.0732 | 0.0977 | 0.1082 | 0.0881 | 0.0890 | 0.1148 | 0.1104 | 0.5970 | 0.5887 | 0.0004 | 0.0000 | 0.0029 | 0.0139 | 0.0644 | 0.1076 | 0.0770 | 0.1129 | 0.6209 | |||
MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1052 | 727 | 435 | 10158 | 216.6 | 37.95 | 134.54 | 228.49 | 169 | 184 | 193 | 205 | 215 | 223 | 235 | 249 | 268 | 0.0475 | 483 | 1.039 | 156.49 | 50.48 | 1 | 0.9218 | 401 | 0.0052 | 14.90 | 5.415 | 0.3014 | 48369.5 | 11100000 | 2630000000 | 636000000000 | 0.4349 | 0.2080 | 0.0000 | 0.0000 | 0.0096 | 0.0000 | 0.0096 | 0.0000 | 0.0382 | 0.0047 | 0.1019 | 0.0606 | 0.1656 | 0.0629 | 0.1624 | 0.0606 | 0.1943 | 0.0956 | 0.3185 | 0.7156 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0186 | 0.0023 | 0.0849 | 0.0621 | 0.1088 | 0.0552 | 0.0928 | 0.0437 | 0.1432 | 0.0759 | 0.5517 | 0.7609 | 0.0000 | 0.1667 | 0.0000 | 0.0000 | 0.0635 | 0.1667 | 0.1905 | 0.3333 | 0.1429 | 0.3333 | 0.2540 | 0.0000 | 0.1270 | 0.0000 | 0.0635 | 0.0000 | 0.1587 | 0.0000 | 0.0000 | 0.0095 | 0.0237 | 0.0616 | 0.1754 | 0.1469 | 0.1280 | 0.1801 | 0.2749 | 5 | 7 | 8 | 9 | 11 | 16 | 98 | 264 | 495 | 0.1308 | 20.25 | 3.815 | 0.5357 | 70302.5 | 49000000 | 40900000000 | 40000000000000 | 0.5326 | 0.1283 | 0.0600 | 0.0028 | 0.2086 | 0.0308 | 0.2229 | 0.1413 | 0.2086 | 0.1636 | 0.1400 | 0.2070 | 0.0686 | 0.1930 | 0.0514 | 0.1035 | 0.0371 | 0.0867 | 0.0029 | 0.0713 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0037 | 0.0047 | 0.0269 | 0.0233 | 0.0561 | 0.0472 | 0.0326 | 0.0315 | 0.0668 | 0.0585 | 0.8136 | 0.8348 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0011 | 0.0020 | 0.0049 | 0.0053 | 0.0377 | 0.0422 | 0.0681 | 0.0763 | 0.0518 | 0.0666 | 0.0883 | 0.0849 | 0.7477 | 0.7223 | 0.0000 | 0.0000 | 0.0011 | 0.0029 | 0.0350 | 0.0622 | 0.0404 | 0.0733 | 0.7851 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1030 | 654 | 4733 | 10425 | 467.9 | 107.24 | 95.77 | 122.81 | 345 | 379 | 404 | 428 | 451 | 479 | 509 | 550 | 613 | 0.0706 | 736 | 0.617 | 150.66 | 41.15 | 1 | 0.0909 | 430 | 0.0008 | 55.01 | 7.358 | 0.1623 | 230448.0 | 120000000 | 65300000000 | 37500000000000 | 0.3787 | 0.2634 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0010 | 0.0007 | 0.0134 | 0.0009 | 0.0647 | 0.0210 | 0.1390 | 0.0495 | 0.1451 | 0.0401 | 0.1678 | 0.0472 | 0.4677 | 0.8406 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0008 | 0.0006 | 0.0057 | 0.0004 | 0.0302 | 0.0145 | 0.0629 | 0.0288 | 0.0577 | 0.0177 | 0.0847 | 0.0228 | 0.7570 | 0.9150 | 0.0023 | 0.0000 | 0.0070 | 0.0000 | 0.0151 | 0.0201 | 0.0568 | 0.0936 | 0.1230 | 0.1472 | 0.1647 | 0.2107 | 0.0974 | 0.1037 | 0.1334 | 0.1171 | 0.4002 | 0.3077 | 0.0005 | 0.0024 | 0.0063 | 0.0250 | 0.0794 | 0.1414 | 0.1034 | 0.1255 | 0.5161 | 8 | 10 | 12 | 16 | 31 | 66 | 119 | 187 | 269 | 0.0567 | 15.85 | 4.921 | 0.5294 | 24254.7 | 8620000 | 3790000000 | 1970000000000 | 0.5285 | 0.1189 | 0.0542 | 0.0020 | 0.2045 | 0.0127 | 0.3074 | 0.1029 | 0.1864 | 0.1470 | 0.1140 | 0.2238 | 0.0695 | 0.2285 | 0.0320 | 0.1142 | 0.0209 | 0.0788 | 0.0111 | 0.0902 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0003 | 0.0011 | 0.0095 | 0.0066 | 0.0504 | 0.0403 | 0.0831 | 0.0816 | 0.0652 | 0.0504 | 0.0967 | 0.0809 | 0.6944 | 0.7391 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0019 | 0.0021 | 0.0107 | 0.0164 | 0.0630 | 0.0649 | 0.1047 | 0.1238 | 0.0740 | 0.0795 | 0.1160 | 0.1196 | 0.6286 | 0.5934 | 0.0000 | 0.0003 | 0.0014 | 0.0107 | 0.0546 | 0.0976 | 0.0658 | 0.1029 | 0.6668 | |||
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 835 | 668 | 9436 | 26949 | 509.0 | 119.52 | 167.87 | 203.60 | 373 | 412 | 441 | 467 | 495 | 522 | 555 | 598 | 668 | 0.0413 | 1112 | 0.662 | 166.43 | 45.61 | 1 | 0.0520 | 491 | 0.0006 | 62.28 | 7.676 | 0.1552 | 273329.0 | 155000000 | 92900000000 | 58900000000000 | 0.4414 | 0.2158 | 0.0005 | 0.0000 | 0.0010 | 0.0001 | 0.0045 | 0.0001 | 0.0160 | 0.0016 | 0.0599 | 0.0173 | 0.1253 | 0.0382 | 0.1333 | 0.0410 | 0.1696 | 0.0533 | 0.4898 | 0.8484 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0056 | 0.0004 | 0.0284 | 0.0114 | 0.0665 | 0.0214 | 0.0584 | 0.0205 | 0.0867 | 0.0273 | 0.7535 | 0.9190 | 0.0030 | 0.0000 | 0.0095 | 0.0141 | 0.0233 | 0.0194 | 0.0531 | 0.0952 | 0.1103 | 0.1411 | 0.1455 | 0.1711 | 0.0960 | 0.0935 | 0.1306 | 0.1323 | 0.4287 | 0.3333 | 0.0002 | 0.0045 | 0.0079 | 0.0271 | 0.0857 | 0.1202 | 0.0911 | 0.1114 | 0.5519 | 8 | 11 | 17 | 36 | 77 | 141 | 218 | 316 | 466 | 0.0551 | 40.07 | 5.701 | 0.4557 | 69631.7 | 39300000 | 26800000000 | 21000000000000 | 0.4485 | 0.1832 | 0.0434 | 0.0008 | 0.1902 | 0.0126 | 0.2802 | 0.1166 | 0.1517 | 0.1613 | 0.1292 | 0.2019 | 0.0888 | 0.1955 | 0.0589 | 0.1175 | 0.0323 | 0.0958 | 0.0254 | 0.0979 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0002 | 0.0093 | 0.0067 | 0.0549 | 0.0483 | 0.1006 | 0.0833 | 0.0610 | 0.0527 | 0.0967 | 0.0874 | 0.6773 | 0.7214 | 0.0002 | 0.0004 | 0.0009 | 0.0003 | 0.0012 | 0.0017 | 0.0175 | 0.0227 | 0.0800 | 0.0909 | 0.1203 | 0.1382 | 0.0793 | 0.0819 | 0.1150 | 0.1299 | 0.5857 | 0.5341 | 0.0000 | 0.0002 | 0.0021 | 0.0123 | 0.0723 | 0.1039 | 0.0750 | 0.1098 | 0.6245 | |
SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 837 | 568 | 3810 | 7691 | 452.3 | 131.47 | 221.21 | 376.57 | 230 | 356 | 426 | 457 | 480 | 503 | 528 | 553 | 586 | 0.0787 | 605 | 1.031 | 95.27 | 22.00 | 2 | 0.0559 | 213 | 0.0026 | 14.07 | 6.352 | 0.2995 | 221894.0 | 114000000 | 60800000000 | 33200000000000 | 0.3620 | 0.2645 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0029 | 0.0000 | 0.0119 | 0.0016 | 0.0530 | 0.0188 | 0.0759 | 0.0350 | 0.0740 | 0.0220 | 0.1050 | 0.0373 | 0.6765 | 0.8854 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0145 | 0.0142 | 0.0290 | 0.0275 | 0.0145 | 0.0133 | 0.0244 | 0.0245 | 0.9162 | 0.9198 | 0.0021 | 0.0000 | 0.0054 | 0.0122 | 0.0171 | 0.0000 | 0.0289 | 0.0427 | 0.0567 | 0.1037 | 0.0739 | 0.0732 | 0.1017 | 0.1220 | 0.1210 | 0.0793 | 0.5931 | 0.5671 | 0.0004 | 0.0017 | 0.0021 | 0.0084 | 0.0261 | 0.0433 | 0.0517 | 0.0685 | 0.7977 | 9 | 14 | 18 | 23 | 32 | 56 | 165 | 387 | 734 | 0.0801 | 36.23 | 4.662 | 0.5714 | 190720.0 | 231000000 | 326000000000 | 505000000000000 | 0.5310 | 0.1283 | 0.0284 | 0.0000 | 0.2074 | 0.0058 | 0.3466 | 0.0902 | 0.1307 | 0.1645 | 0.1392 | 0.2082 | 0.0881 | 0.2475 | 0.0256 | 0.1092 | 0.0227 | 0.0975 | 0.0114 | 0.0771 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0008 | 0.0089 | 0.0041 | 0.0491 | 0.0454 | 0.0930 | 0.0827 | 0.0637 | 0.0458 | 0.0885 | 0.0827 | 0.6963 | 0.7387 | 0.0000 | 0.0006 | 0.0005 | 0.0011 | 0.0052 | 0.0017 | 0.0063 | 0.0112 | 0.0645 | 0.0730 | 0.1096 | 0.1162 | 0.0739 | 0.0691 | 0.1070 | 0.1072 | 0.6329 | 0.6199 | 0.0000 | 0.0005 | 0.0029 | 0.0082 | 0.0629 | 0.0936 | 0.0739 | 0.0975 | 0.6606 | |||
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 420 | 742 | 10935 | 36965 | 570.5 | 116.52 | 204.39 | 357.85 | 434 | 472 | 502 | 530 | 557 | 586 | 619 | 663 | 727 | 0.0445 | 1646 | 1.010 | 102.55 | 38.05 | 2 | 0.0258 | 282 | 0.0006 | 81.76 | 7.769 | 0.1488 | 339006.0 | 210000000 | 136000000000 | 92000000000000 | 0.4191 | 0.2288 | 0.0003 | 0.0000 | 0.0004 | 0.0000 | 0.0035 | 0.0003 | 0.0113 | 0.0011 | 0.0543 | 0.0126 | 0.1116 | 0.0285 | 0.1155 | 0.0282 | 0.1447 | 0.0456 | 0.5584 | 0.8837 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0011 | 0.0000 | 0.0039 | 0.0003 | 0.0256 | 0.0086 | 0.0516 | 0.0165 | 0.0554 | 0.0121 | 0.0712 | 0.0199 | 0.7907 | 0.9426 | 0.0034 | 0.0123 | 0.0069 | 0.0369 | 0.0195 | 0.0541 | 0.0653 | 0.1253 | 0.1146 | 0.1695 | 0.1725 | 0.1892 | 0.1135 | 0.0983 | 0.1358 | 0.1007 | 0.3685 | 0.2138 | 0.0006 | 0.0044 | 0.0105 | 0.0277 | 0.0720 | 0.1148 | 0.0938 | 0.1191 | 0.5571 | 6 | 8 | 9 | 11 | 14 | 35 | 134 | 381 | 754 | 0.1781 | 65.60 | 4.468 | 0.5873 | 169829.0 | 188000000 | 243000000000 | 352000000000000 | 0.4094 | 0.2312 | 0.1194 | 0.0037 | 0.3132 | 0.0514 | 0.3248 | 0.2365 | 0.1171 | 0.2139 | 0.0620 | 0.1913 | 0.0302 | 0.1403 | 0.0225 | 0.0740 | 0.0078 | 0.0503 | 0.0031 | 0.0385 | 0.0000 | 0.0000 | 0.0001 | 0.0002 | 0.0004 | 0.0009 | 0.0066 | 0.0033 | 0.0399 | 0.0364 | 0.0767 | 0.0693 | 0.0521 | 0.0427 | 0.0787 | 0.0708 | 0.7456 | 0.7764 | 0.0000 | 0.0000 | 0.0001 | 0.0003 | 0.0010 | 0.0015 | 0.0075 | 0.0101 | 0.0502 | 0.0538 | 0.0946 | 0.1037 | 0.0644 | 0.0702 | 0.0978 | 0.1071 | 0.6844 | 0.6533 | 0.0000 | 0.0002 | 0.0006 | 0.0068 | 0.0462 | 0.0827 | 0.0597 | 0.0911 | 0.7127 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 828 | 486 | 14994 | 31048 | 470.7 | 84.93 | 145.23 | 202.56 | 364 | 398 | 424 | 447 | 469 | 490 | 513 | 542 | 583 | 0.0407 | 1265 | 1.143 | 89.20 | 33.84 | 2 | 0.0156 | 234 | 0.0008 | 39.09 | 7.354 | 0.1815 | 228773.0 | 115000000 | 59000000000 | 31200000000000 | 0.4389 | 0.2085 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0020 | 0.0001 | 0.0111 | 0.0005 | 0.0411 | 0.0092 | 0.0890 | 0.0204 | 0.0990 | 0.0211 | 0.1268 | 0.0342 | 0.6308 | 0.9146 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0049 | 0.0001 | 0.0183 | 0.0077 | 0.0417 | 0.0152 | 0.0417 | 0.0114 | 0.0544 | 0.0195 | 0.8381 | 0.9459 | 0.0048 | 0.0278 | 0.0077 | 0.0556 | 0.0191 | 0.1065 | 0.0689 | 0.1991 | 0.1411 | 0.2083 | 0.1689 | 0.1435 | 0.1325 | 0.0694 | 0.1536 | 0.1019 | 0.3033 | 0.0880 | 0.0004 | 0.0009 | 0.0068 | 0.0261 | 0.0682 | 0.1054 | 0.0961 | 0.1216 | 0.5745 | 6 | 8 | 10 | 13 | 30 | 83 | 171 | 296 | 457 | 0.1239 | 27.73 | 4.902 | 0.5414 | 62118.6 | 35000000 | 22900000000 | 16700000000000 | 0.4409 | 0.1994 | 0.0472 | 0.0018 | 0.1760 | 0.0086 | 0.2720 | 0.1069 | 0.1840 | 0.1494 | 0.1220 | 0.1901 | 0.0838 | 0.2070 | 0.0520 | 0.1123 | 0.0355 | 0.0968 | 0.0276 | 0.1271 | 0.0004 | 0.0000 | 0.0002 | 0.0003 | 0.0004 | 0.0005 | 0.0104 | 0.0070 | 0.0419 | 0.0383 | 0.0677 | 0.0587 | 0.0504 | 0.0418 | 0.0695 | 0.0619 | 0.7590 | 0.7915 | 0.0002 | 0.0002 | 0.0013 | 0.0006 | 0.0008 | 0.0007 | 0.0105 | 0.0168 | 0.0580 | 0.0609 | 0.0871 | 0.0932 | 0.0560 | 0.0646 | 0.0902 | 0.0922 | 0.6960 | 0.6707 | 0.0000 | 0.0003 | 0.0015 | 0.0114 | 0.0475 | 0.0781 | 0.0516 | 0.0805 | 0.7292 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 141 | 279 | 6550 | 28560 | 325.2 | 76.94 | 118.00 | 205.38 | 229 | 259 | 281 | 299 | 318 | 339 | 361 | 391 | 431 | 0.0380 | 1086 | 1.019 | 88.10 | 26.68 | 3 | 0.0337 | 221 | 0.0007 | 63.80 | 7.487 | 0.1467 | 111704.0 | 40400000 | 15300000000 | 6070000000000 | 0.4422 | 0.2121 | 0.0000 | 0.0000 | 0.0015 | 0.0002 | 0.0067 | 0.0012 | 0.0248 | 0.0030 | 0.0781 | 0.0206 | 0.1554 | 0.0495 | 0.1682 | 0.0513 | 0.1992 | 0.0834 | 0.3659 | 0.7909 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0006 | 0.0003 | 0.0069 | 0.0006 | 0.0339 | 0.0127 | 0.0714 | 0.0286 | 0.0678 | 0.0219 | 0.0992 | 0.0413 | 0.7200 | 0.8945 | 0.0053 | 0.0096 | 0.0114 | 0.0288 | 0.0220 | 0.0745 | 0.0676 | 0.0962 | 0.1277 | 0.1923 | 0.1634 | 0.1635 | 0.1087 | 0.1130 | 0.1664 | 0.1394 | 0.3275 | 0.1827 | 0.0010 | 0.0043 | 0.0085 | 0.0299 | 0.0768 | 0.1404 | 0.1063 | 0.1358 | 0.4970 | 7 | 9 | 10 | 12 | 16 | 29 | 83 | 200 | 398 | 0.1579 | 24.15 | 4.168 | 0.5959 | 56105.0 | 38900000 | 32800000000 | 31500000000000 | 0.4719 | 0.1982 | 0.0778 | 0.0031 | 0.2645 | 0.0291 | 0.3497 | 0.1507 | 0.1482 | 0.1884 | 0.0819 | 0.2342 | 0.0426 | 0.1740 | 0.0180 | 0.0983 | 0.0098 | 0.0746 | 0.0074 | 0.0478 | 0.0000 | 0.0001 | 0.0004 | 0.0002 | 0.0004 | 0.0003 | 0.0067 | 0.0067 | 0.0467 | 0.0397 | 0.0880 | 0.0720 | 0.0536 | 0.0512 | 0.0899 | 0.0787 | 0.7143 | 0.7511 | 0.0001 | 0.0003 | 0.0004 | 0.0012 | 0.0016 | 0.0016 | 0.0092 | 0.0145 | 0.0557 | 0.0597 | 0.1096 | 0.1123 | 0.0663 | 0.0794 | 0.1060 | 0.1115 | 0.6510 | 0.6194 | 0.0000 | 0.0001 | 0.0019 | 0.0094 | 0.0525 | 0.0917 | 0.0654 | 0.0947 | 0.6842 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 489 | 834 | 12111 | 18609 | 541.6 | 118.52 | 168.67 | 182.80 | 399 | 441 | 476 | 505 | 532 | 559 | 589 | 628 | 690 | 0.0564 | 1049 | 1.226 | 127.68 | 55.00 | 1 | 0.0283 | 343 | 0.0010 | 25.57 | 7.191 | 0.2311 | 307350.0 | 183000000 | 114000000000 | 74500000000000 | 0.4223 | 0.2210 | 0.0002 | 0.0001 | 0.0011 | 0.0003 | 0.0035 | 0.0002 | 0.0121 | 0.0018 | 0.0351 | 0.0123 | 0.0639 | 0.0223 | 0.0770 | 0.0188 | 0.1064 | 0.0282 | 0.7006 | 0.9161 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0017 | 0.0002 | 0.0050 | 0.0010 | 0.0150 | 0.0084 | 0.0268 | 0.0140 | 0.0306 | 0.0093 | 0.0434 | 0.0135 | 0.8767 | 0.9536 | 0.0032 | 0.0045 | 0.0053 | 0.0061 | 0.0150 | 0.0151 | 0.0513 | 0.0363 | 0.0898 | 0.0802 | 0.1165 | 0.1104 | 0.1010 | 0.0726 | 0.1112 | 0.1104 | 0.5067 | 0.5643 | 0.0016 | 0.0023 | 0.0060 | 0.0213 | 0.0499 | 0.0789 | 0.0809 | 0.1040 | 0.6550 | 8 | 14 | 27 | 56 | 102 | 159 | 227 | 312 | 435 | 0.0253 | 65.01 | 6.264 | 0.3576 | 61863.3 | 30100000 | 17400000000 | 11500000000000 | 0.4777 | 0.1891 | 0.0835 | 0.0023 | 0.2306 | 0.0249 | 0.2838 | 0.1678 | 0.1513 | 0.1698 | 0.1153 | 0.1751 | 0.0782 | 0.1769 | 0.0402 | 0.1114 | 0.0146 | 0.0964 | 0.0026 | 0.0755 | 0.0004 | 0.0001 | 0.0000 | 0.0000 | 0.0005 | 0.0009 | 0.0147 | 0.0085 | 0.0655 | 0.0544 | 0.1197 | 0.0976 | 0.0848 | 0.0670 | 0.1186 | 0.1038 | 0.5959 | 0.6678 | 0.0000 | 0.0007 | 0.0011 | 0.0021 | 0.0057 | 0.0062 | 0.0239 | 0.0327 | 0.0959 | 0.1092 | 0.1534 | 0.1697 | 0.1026 | 0.1133 | 0.1390 | 0.1561 | 0.4782 | 0.4101 | 0.0001 | 0.0000 | 0.0024 | 0.0177 | 0.0832 | 0.1361 | 0.0944 | 0.1341 | 0.5320 | |||
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 592 | 492 | 4236 | 12697 | 651.9 | 140.09 | 147.12 | 254.46 | 443 | 556 | 603 | 639 | 676 | 704 | 732 | 763 | 805 | 0.0784 | 995 | 1.202 | 120.07 | 45.18 | 3 | 0.0708 | 300 | 0.0015 | 22.93 | 6.808 | 0.2599 | 444572.0 | 313000000 | 227000000000 | 168000000000000 | 0.4044 | 0.2398 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0034 | 0.0003 | 0.0058 | 0.0021 | 0.0378 | 0.0206 | 0.0903 | 0.0398 | 0.0701 | 0.0247 | 0.1192 | 0.0367 | 0.6731 | 0.8759 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0003 | 0.0006 | 0.0013 | 0.0152 | 0.0187 | 0.0336 | 0.0329 | 0.0175 | 0.0152 | 0.0336 | 0.0255 | 0.8987 | 0.9062 | 0.0079 | 0.0000 | 0.0111 | 0.0154 | 0.0300 | 0.1385 | 0.0679 | 0.1385 | 0.1153 | 0.2308 | 0.1801 | 0.1846 | 0.1153 | 0.1385 | 0.1485 | 0.1231 | 0.3239 | 0.0308 | 0.0000 | 0.0017 | 0.0033 | 0.0079 | 0.0426 | 0.0857 | 0.0662 | 0.0919 | 0.7007 | 8 | 9 | 11 | 14 | 20 | 38 | 105 | 241 | 506 | 0.1619 | 33.70 | 4.314 | 0.6111 | 86390.9 | 71500000 | 69700000000 | 75500000000000 | 0.6018 | 0.0757 | 0.0644 | 0.0043 | 0.2356 | 0.0325 | 0.2932 | 0.1702 | 0.1458 | 0.1856 | 0.1136 | 0.2002 | 0.0661 | 0.1856 | 0.0373 | 0.0821 | 0.0305 | 0.0736 | 0.0136 | 0.0659 | 0.0000 | 0.0003 | 0.0014 | 0.0000 | 0.0005 | 0.0025 | 0.0096 | 0.0093 | 0.0536 | 0.0496 | 0.1026 | 0.0981 | 0.0517 | 0.0496 | 0.0780 | 0.0733 | 0.7027 | 0.7174 | 0.0003 | 0.0007 | 0.0013 | 0.0004 | 0.0023 | 0.0011 | 0.0134 | 0.0173 | 0.0623 | 0.0665 | 0.1086 | 0.1122 | 0.0633 | 0.0725 | 0.0939 | 0.0952 | 0.6546 | 0.6341 | 0.0000 | 0.0012 | 0.0024 | 0.0150 | 0.0559 | 0.1057 | 0.0574 | 0.0811 | 0.6813 | |
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 603 | 689 | 7600 | 15811 | 210.9 | 43.78 | 142.17 | 171.25 | 159 | 173 | 185 | 196 | 207 | 218 | 230 | 245 | 269 | 0.0623 | 985 | 1.140 | 88.32 | 39.01 | 1 | 0.0330 | 251 | 0.0011 | 39.63 | 7.083 | 0.1887 | 46382.0 | 10600000 | 2540000000 | 632000000000 | 0.4649 | 0.1876 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0031 | 0.0000 | 0.0156 | 0.0013 | 0.0581 | 0.0167 | 0.1363 | 0.0365 | 0.1516 | 0.0327 | 0.1761 | 0.0584 | 0.4584 | 0.8545 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0074 | 0.0004 | 0.0307 | 0.0110 | 0.0643 | 0.0228 | 0.0646 | 0.0137 | 0.0939 | 0.0247 | 0.7375 | 0.9274 | 0.0050 | 0.0238 | 0.0058 | 0.0149 | 0.0284 | 0.0387 | 0.0984 | 0.1310 | 0.1418 | 0.1786 | 0.1818 | 0.1994 | 0.0992 | 0.1012 | 0.1276 | 0.1250 | 0.3119 | 0.1875 | 0.0009 | 0.0020 | 0.0111 | 0.0386 | 0.0873 | 0.1384 | 0.1199 | 0.1335 | 0.4684 | 11 | 13 | 15 | 21 | 53 | 120 | 192 | 279 | 392 | 0.0646 | 26.36 | 5.217 | 0.4922 | 49534.8 | 23000000 | 12600000000 | 7870000000000 | 0.5544 | 0.1062 | 0.0575 | 0.0021 | 0.2553 | 0.0185 | 0.3274 | 0.1627 | 0.1596 | 0.1906 | 0.0883 | 0.1964 | 0.0624 | 0.1886 | 0.0300 | 0.1011 | 0.0130 | 0.0719 | 0.0065 | 0.0682 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0005 | 0.0010 | 0.0079 | 0.0052 | 0.0517 | 0.0451 | 0.0963 | 0.0833 | 0.0703 | 0.0593 | 0.0991 | 0.0835 | 0.6739 | 0.7223 | 0.0002 | 0.0004 | 0.0013 | 0.0015 | 0.0029 | 0.0043 | 0.0140 | 0.0201 | 0.0689 | 0.0788 | 0.1235 | 0.1391 | 0.0936 | 0.0936 | 0.1214 | 0.1176 | 0.5743 | 0.5445 | 0.0000 | 0.0003 | 0.0017 | 0.0095 | 0.0610 | 0.1104 | 0.0758 | 0.1149 | 0.6263 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 312 | 733 | 7233 | 20217 | 523.9 | 88.32 | 192.73 | 354.08 | 412 | 444 | 470 | 496 | 519 | 544 | 571 | 604 | 641 | 0.0504 | 1018 | 1.154 | 114.98 | 42.58 | 1 | 0.0408 | 295 | 0.0018 | 19.88 | 6.575 | 0.2459 | 282245.0 | 156000000 | 88600000000 | 51500000000000 | 0.4172 | 0.2311 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0003 | 0.0114 | 0.0004 | 0.0461 | 0.0113 | 0.0920 | 0.0228 | 0.1143 | 0.0150 | 0.1514 | 0.0291 | 0.5824 | 0.9210 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0046 | 0.0001 | 0.0219 | 0.0096 | 0.0442 | 0.0195 | 0.0517 | 0.0096 | 0.0720 | 0.0186 | 0.8052 | 0.9427 | 0.0032 | 0.0494 | 0.0085 | 0.0247 | 0.0481 | 0.0617 | 0.1068 | 0.2099 | 0.1474 | 0.1481 | 0.1699 | 0.1728 | 0.1453 | 0.1605 | 0.1271 | 0.1111 | 0.2436 | 0.0617 | 0.0014 | 0.0026 | 0.0072 | 0.0203 | 0.0629 | 0.1090 | 0.0973 | 0.1296 | 0.5697 | 10 | 12 | 14 | 16 | 19 | 32 | 110 | 339 | 644 | 0.1456 | 63.21 | 4.433 | 0.6015 | 162507.0 | 200000000 | 303000000000 | 525000000000000 | 0.5064 | 0.1533 | 0.1318 | 0.0049 | 0.3100 | 0.0323 | 0.3324 | 0.2391 | 0.1234 | 0.2742 | 0.0561 | 0.2167 | 0.0351 | 0.1220 | 0.0042 | 0.0617 | 0.0056 | 0.0358 | 0.0014 | 0.0133 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0005 | 0.0003 | 0.0070 | 0.0065 | 0.0491 | 0.0410 | 0.0772 | 0.0740 | 0.0498 | 0.0478 | 0.0813 | 0.0702 | 0.7351 | 0.7600 | 0.0000 | 0.0000 | 0.0002 | 0.0002 | 0.0004 | 0.0017 | 0.0119 | 0.0114 | 0.0544 | 0.0623 | 0.0908 | 0.0925 | 0.0634 | 0.0717 | 0.0934 | 0.1071 | 0.6854 | 0.6531 | 0.0000 | 0.0002 | 0.0008 | 0.0084 | 0.0511 | 0.0851 | 0.0532 | 0.0876 | 0.7136 | |
MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1078 | 523 | 14942 | 30535 | 213.6 | 65.41 | 182.99 | 225.98 | 137 | 159 | 176 | 193 | 208 | 224 | 242 | 265 | 299 | 0.0495 | 1511 | 0.501 | 139.13 | 33.29 | 9 | 0.0285 | 426 | 0.0011 | 32.46 | 7.146 | 0.2116 | 49882.5 | 12600000 | 3430000000 | 996000000000 | 0.4707 | 0.1872 | 0.0008 | 0.0000 | 0.0026 | 0.0002 | 0.0114 | 0.0010 | 0.0396 | 0.0054 | 0.1050 | 0.0284 | 0.1755 | 0.0659 | 0.1723 | 0.0644 | 0.1742 | 0.0921 | 0.3187 | 0.7427 | 0.0005 | 0.0000 | 0.0007 | 0.0001 | 0.0015 | 0.0002 | 0.0105 | 0.0022 | 0.0389 | 0.0148 | 0.0680 | 0.0352 | 0.0666 | 0.0291 | 0.0852 | 0.0452 | 0.7281 | 0.8731 | 0.0023 | 0.0054 | 0.0057 | 0.0075 | 0.0154 | 0.0299 | 0.0570 | 0.0680 | 0.1115 | 0.1497 | 0.1591 | 0.1844 | 0.1081 | 0.1163 | 0.1420 | 0.1306 | 0.3989 | 0.3082 | 0.0007 | 0.0032 | 0.0068 | 0.0241 | 0.0727 | 0.1106 | 0.0894 | 0.1272 | 0.5653 | 7 | 9 | 13 | 25 | 64 | 146 | 254 | 375 | 525 | 0.0542 | 24.53 | 5.282 | 0.4416 | 84546.7 | 50200000 | 34700000000 | 26800000000000 | 0.4917 | 0.1628 | 0.0917 | 0.0009 | 0.2762 | 0.0235 | 0.3457 | 0.2055 | 0.1342 | 0.1964 | 0.0753 | 0.2196 | 0.0473 | 0.1648 | 0.0208 | 0.0975 | 0.0068 | 0.0592 | 0.0019 | 0.0325 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0005 | 0.0007 | 0.0084 | 0.0060 | 0.0544 | 0.0468 | 0.0935 | 0.0840 | 0.0596 | 0.0515 | 0.0953 | 0.0815 | 0.6877 | 0.7291 | 0.0001 | 0.0001 | 0.0001 | 0.0004 | 0.0013 | 0.0016 | 0.0121 | 0.0199 | 0.0750 | 0.0811 | 0.1193 | 0.1295 | 0.0741 | 0.0859 | 0.1155 | 0.1244 | 0.6026 | 0.5571 | 0.0002 | 0.0002 | 0.0006 | 0.0101 | 0.0639 | 0.1058 | 0.0698 | 0.1080 | 0.6414 | |
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 735 | 770 | 6091 | 18694 | 277.5 | 59.08 | 146.13 | 189.54 | 207 | 227 | 242 | 257 | 270 | 286 | 303 | 325 | 360 | 0.0517 | 966 | 1.132 | 134.38 | 47.43 | 1 | 0.0545 | 332 | 0.0007 | 64.70 | 7.464 | 0.1528 | 80490.5 | 24400000 | 7720000000 | 2550000000000 | 0.4323 | 0.2199 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0027 | 0.0000 | 0.0154 | 0.0014 | 0.0654 | 0.0175 | 0.1429 | 0.0415 | 0.1509 | 0.0382 | 0.1728 | 0.0693 | 0.4499 | 0.8321 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0079 | 0.0003 | 0.0304 | 0.0134 | 0.0630 | 0.0205 | 0.0642 | 0.0152 | 0.0902 | 0.0304 | 0.7430 | 0.9203 | 0.0019 | 0.0132 | 0.0096 | 0.0166 | 0.0182 | 0.0795 | 0.0738 | 0.1358 | 0.1381 | 0.1821 | 0.1937 | 0.2318 | 0.1035 | 0.0762 | 0.1505 | 0.1126 | 0.3106 | 0.1523 | 0.0018 | 0.0033 | 0.0109 | 0.0301 | 0.0733 | 0.1309 | 0.1099 | 0.1193 | 0.5205 | 9 | 11 | 12 | 15 | 30 | 105 | 203 | 301 | 416 | 0.1325 | 29.91 | 4.805 | 0.5468 | 57276.7 | 29800000 | 18600000000 | 13400000000000 | 0.5440 | 0.1256 | 0.0714 | 0.0031 | 0.2395 | 0.0243 | 0.3145 | 0.1494 | 0.1559 | 0.2050 | 0.1263 | 0.2205 | 0.0462 | 0.1803 | 0.0314 | 0.0985 | 0.0096 | 0.0681 | 0.0052 | 0.0508 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0006 | 0.0059 | 0.0032 | 0.0420 | 0.0353 | 0.0761 | 0.0653 | 0.0627 | 0.0511 | 0.0960 | 0.0756 | 0.7167 | 0.7688 | 0.0002 | 0.0000 | 0.0007 | 0.0009 | 0.0015 | 0.0021 | 0.0100 | 0.0122 | 0.0607 | 0.0697 | 0.1088 | 0.1264 | 0.0830 | 0.0840 | 0.1178 | 0.1284 | 0.6173 | 0.5762 | 0.0000 | 0.0004 | 0.0006 | 0.0073 | 0.0536 | 0.0927 | 0.0730 | 0.1036 | 0.6688 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1215 | 337 | 5299 | 15208 | 314.6 | 49.18 | 289.78 | 445.68 | 258 | 273 | 285 | 295 | 306 | 318 | 334 | 356 | 383 | 0.0592 | 900 | 0.916 | 116.83 | 42.76 | 1 | 0.0670 | 355 | 0.0017 | 23.16 | 6.655 | 0.2317 | 101403.0 | 33500000 | 11400000000 | 3950000000000 | 0.3986 | 0.2511 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0000 | 0.0093 | 0.0002 | 0.0305 | 0.0140 | 0.0753 | 0.0305 | 0.0827 | 0.0190 | 0.1286 | 0.0295 | 0.6705 | 0.9068 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0000 | 0.0158 | 0.0117 | 0.0404 | 0.0247 | 0.0404 | 0.0102 | 0.0640 | 0.0160 | 0.8348 | 0.9373 | 0.0063 | 0.0000 | 0.0158 | 0.0000 | 0.0412 | 0.0000 | 0.0824 | 0.0000 | 0.1173 | 0.0000 | 0.1347 | 0.0000 | 0.1094 | 0.0000 | 0.1410 | 0.0000 | 0.3518 | 0.0000 | 0.0022 | 0.0083 | 0.0188 | 0.0419 | 0.0777 | 0.1104 | 0.0877 | 0.1144 | 0.5386 | 14 | 17 | 20 | 24 | 37 | 96 | 310 | 568 | 955 | 0.0512 | 92.27 | 5.412 | 0.4889 | 282587.0 | 374000000 | 589000000000 | 1.04E+15 | 0.4260 | 0.2078 | 0.0678 | 0.0021 | 0.2554 | 0.0310 | 0.2713 | 0.1590 | 0.1515 | 0.1654 | 0.1154 | 0.1977 | 0.0736 | 0.1668 | 0.0375 | 0.0880 | 0.0202 | 0.0992 | 0.0072 | 0.0908 | 0.0000 | 0.0000 | 0.0002 | 0.0006 | 0.0006 | 0.0002 | 0.0058 | 0.0039 | 0.0392 | 0.0362 | 0.0676 | 0.0614 | 0.0464 | 0.0369 | 0.0642 | 0.0614 | 0.7760 | 0.7994 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0016 | 0.0038 | 0.0107 | 0.0111 | 0.0513 | 0.0494 | 0.0801 | 0.0970 | 0.0632 | 0.0688 | 0.0880 | 0.0932 | 0.7051 | 0.6762 | 0.0000 | 0.0000 | 0.0009 | 0.0068 | 0.0458 | 0.0717 | 0.0503 | 0.0824 | 0.7421 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 442 | 641 | 7990 | 25118 | 501.3 | 88.04 | 166.84 | 265.28 | 388 | 427 | 453 | 476 | 498 | 523 | 548 | 577 | 617 | 0.0471 | 1183 | 1.180 | 95.02 | 43.97 | 2 | 0.0333 | 266 | 0.0018 | 18.67 | 6.558 | 0.2470 | 259095.0 | 138000000 | 75200000000 | 42100000000000 | 0.4349 | 0.2174 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0022 | 0.0004 | 0.0081 | 0.0004 | 0.0446 | 0.0106 | 0.0956 | 0.0227 | 0.1034 | 0.0182 | 0.1448 | 0.0317 | 0.6006 | 0.9161 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0009 | 0.0003 | 0.0024 | 0.0004 | 0.0209 | 0.0097 | 0.0427 | 0.0195 | 0.0421 | 0.0112 | 0.0628 | 0.0166 | 0.8279 | 0.9424 | 0.0064 | 0.0682 | 0.0091 | 0.0455 | 0.0320 | 0.0795 | 0.0970 | 0.1591 | 0.1473 | 0.2045 | 0.1802 | 0.1591 | 0.1180 | 0.0795 | 0.1455 | 0.0909 | 0.2644 | 0.1136 | 0.0005 | 0.0038 | 0.0054 | 0.0222 | 0.0749 | 0.1073 | 0.1055 | 0.1318 | 0.5485 | 10 | 11 | 14 | 16 | 23 | 59 | 162 | 310 | 534 | 0.1363 | 42.26 | 4.688 | 0.5832 | 98205.2 | 84400000 | 91600000000 | 119000000000000 | 0.4503 | 0.1832 | 0.0986 | 0.0041 | 0.2120 | 0.0293 | 0.2896 | 0.1678 | 0.1638 | 0.1659 | 0.1033 | 0.2136 | 0.0800 | 0.1794 | 0.0287 | 0.0875 | 0.0194 | 0.0736 | 0.0047 | 0.0788 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0006 | 0.0008 | 0.0081 | 0.0047 | 0.0452 | 0.0417 | 0.0840 | 0.0727 | 0.0594 | 0.0422 | 0.0840 | 0.0743 | 0.7185 | 0.7635 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0024 | 0.0121 | 0.0159 | 0.0604 | 0.0675 | 0.1040 | 0.1154 | 0.0752 | 0.0819 | 0.1097 | 0.1185 | 0.6378 | 0.5984 | 0.0000 | 0.0001 | 0.0012 | 0.0086 | 0.0549 | 0.0904 | 0.0693 | 0.0991 | 0.6764 |