High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 382 | 482 | | 6733 | 6438 | 43.2 | 12.21 | 112.41 | 165.59 | 28 | 32 | 35 | 39 | 42 | 46 | 50 | 54 | 60 | 0.1785 | 1149 | 1.039 | 54.34 | 16.16 | 3 | 0.0192 | 129 | 0.0360 | 0.84 | 3.592 | 0.6983 | 2014.6 | 100311 | 5270000 | 290000000 | 0.3887 | 0.2344 | 0.0060 | 0.0014 | 0.0139 | 0.0039 | 0.0220 | 0.0043 | 0.0460 | 0.0107 | 0.0794 | 0.0318 | 0.1389 | 0.0469 | 0.1480 | 0.0529 | 0.1880 | 0.0959 | 0.3578 | 0.7522 | 0.0027 | 0.0005 | 0.0041 | 0.0010 | 0.0078 | 0.0010 | 0.0188 | 0.0052 | 0.0347 | 0.0229 | 0.0580 | 0.0316 | 0.0586 | 0.0321 | 0.0858 | 0.0495 | 0.7295 | 0.8563 | 0.0070 | 0.0313 | 0.0186 | 0.0224 | 0.0256 | 0.0328 | 0.0413 | 0.0627 | 0.0721 | 0.0687 | 0.0809 | 0.1224 | 0.0878 | 0.1328 | 0.1268 | 0.1597 | 0.5398 | 0.3672 | 0.0033 | 0.0090 | 0.0189 | 0.0269 | 0.0452 | 0.0619 | 0.0736 | 0.0984 | 0.6628 | 7 | 8 | 10 | 12 | 19 | 48 | 124 | 221 | 345 | 0.0718 | 6.66 | 3.779 | 0.5031 | 40050.5 | 19600000 | 11300000000 | 7260000000000 | 0.4549 | 0.1859 | 0.0359 | 0.0046 | 0.1257 | 0.0170 | 0.2036 | 0.0880 | 0.1916 | 0.1173 | 0.1796 | 0.1867 | 0.1168 | 0.1929 | 0.0778 | 0.1312 | 0.0539 | 0.1281 | 0.0150 | 0.1343 | 0.0005 | 0.0008 | 0.0014 | 0.0021 | 0.0023 | 0.0008 | 0.0087 | 0.0068 | 0.0407 | 0.0343 | 0.0535 | 0.0525 | 0.0512 | 0.0423 | 0.0699 | 0.0728 | 0.7719 | 0.7875 | 0.0005 | 0.0000 | 0.0000 | 0.0012 | 0.0022 | 0.0041 | 0.0097 | 0.0146 | 0.0529 | 0.0578 | 0.0707 | 0.0776 | 0.0723 | 0.0712 | 0.0960 | 0.0968 | 0.6958 | 0.6768 | 0.0000 | 0.0010 | 0.0035 | 0.0144 | 0.0416 | 0.0575 | 0.0615 | 0.0878 | 0.7328 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 355 | 693 | | 1758 | 9747 | 194.5 | 65.03 | 7.39 | 2.56 | 126 | 140 | 153 | 164 | 173 | 189 | 216 | 254 | 297 | 0.0806 | 786 | 1.223 | 29.83 | 11.66 | 2 | 0.0438 | 77 | 0.0089 | 2.56 | 5.059 | 0.5219 | 42048.1 | 10100000 | 2640000000 | 742000000000 | 0.3576 | 0.2730 | 0.0013 | 0.0000 | 0.0053 | 0.0007 | 0.0093 | 0.0043 | 0.0200 | 0.0100 | 0.0787 | 0.0400 | 0.1267 | 0.0557 | 0.1067 | 0.0550 | 0.1440 | 0.0764 | 0.5080 | 0.7580 | 0.0008 | 0.0000 | 0.0034 | 0.0006 | 0.0050 | 0.0024 | 0.0101 | 0.0078 | 0.0378 | 0.0269 | 0.0512 | 0.0305 | 0.0419 | 0.0335 | 0.0680 | 0.0449 | 0.7819 | 0.8533 | 0.0023 | 0.0037 | 0.0000 | 0.0037 | 0.0000 | 0.0000 | 0.0090 | 0.0186 | 0.0498 | 0.0520 | 0.0611 | 0.0892 | 0.0452 | 0.0520 | 0.0656 | 0.0743 | 0.7670 | 0.7063 | 0.0000 | 0.0000 | 0.0030 | 0.0076 | 0.0318 | 0.0636 | 0.0394 | 0.0561 | 0.7985 | 4 | 5 | 6 | 7 | 7 | 8 | 8 | 9 | 11 | 0.0172 | 8.20 | 4.461 | 0.3585 | 61.1 | 562.508 | 5723.84 | 64032.1 | 0.4837 | 0.1687 | 0.0143 | 0.0020 | 0.0491 | 0.0072 | 0.1154 | 0.0186 | 0.1968 | 0.0459 | 0.2244 | 0.0938 | 0.2015 | 0.1724 | 0.1356 | 0.2637 | 0.0542 | 0.2652 | 0.0087 | 0.1312 | 0.0012 | 0.0000 | 0.0093 | 0.0006 | 0.0270 | 0.0038 | 0.0627 | 0.0130 | 0.1007 | 0.0342 | 0.1357 | 0.0750 | 0.1749 | 0.1500 | 0.2022 | 0.2720 | 0.2862 | 0.4515 | 0.1173 | 0.1778 | 0.1454 | 0.1541 | 0.1396 | 0.1171 | 0.1150 | 0.1141 | 0.1015 | 0.0801 | 0.0904 | 0.0898 | 0.0869 | 0.0746 | 0.0800 | 0.0728 | 0.1238 | 0.1195 | 0.0077 | 0.0301 | 0.0649 | 0.1143 | 0.1463 | 0.1559 | 0.1546 | 0.1313 | 0.1950 |
| Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 369 | 897 | | 508 | 2542 | 168.7 | 101.76 | 78.27 | 159.27 | 36 | 52 | 79 | 122 | 170 | 212 | 254 | 284 | 304 | 0.1326 | 337 | 0.963 | 124.46 | 46.23 | 1 | 0.6909 | 351 | 0.0029 | 78.06 | 5.974 | 0.1808 | 38792.0 | 10100000 | 2760000000 | 778000000000 | 0.2699 | 0.3263 | 0.0000 | 0.0000 | 0.0278 | 0.0000 | 0.2917 | 0.0000 | 0.3889 | 0.0065 | 0.1528 | 0.1883 | 0.0556 | 0.3701 | 0.0556 | 0.2013 | 0.0278 | 0.0909 | 0.0000 | 0.1429 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0104 | 0.0000 | 0.0519 | 0.0604 | 0.0900 | 0.0876 | 0.0484 | 0.0363 | 0.0727 | 0.0695 | 0.7266 | 0.7462 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0092 | 0.0113 | 0.0553 | 0.0791 | 0.1244 | 0.1017 | 0.0369 | 0.0508 | 0.0691 | 0.0904 | 0.7051 | 0.6667 | 0.0000 | 0.0000 | 0.0039 | 0.0039 | 0.0547 | 0.1094 | 0.0352 | 0.0742 | 0.7188 | 14 | 16 | 18 | 20 | 22 | 28 | 42 | 75 | 198 | 0.0967 | 17.71 | 3.564 | 0.6230 | 31483.0 | 24000000 | 22900000000 | 24100000000000 | 0.5318 | 0.1158 | 0.1119 | 0.0000 | 0.3731 | 0.0552 | 0.2836 | 0.1595 | 0.0970 | 0.2209 | 0.0672 | 0.2331 | 0.0299 | 0.1626 | 0.0299 | 0.0890 | 0.0075 | 0.0491 | 0.0000 | 0.0307 | 0.0000 | 0.0000 | 0.0035 | 0.0014 | 0.0086 | 0.0043 | 0.0276 | 0.0340 | 0.1261 | 0.1007 | 0.1572 | 0.1277 | 0.0950 | 0.0879 | 0.1295 | 0.1433 | 0.4525 | 0.5007 | 0.0000 | 0.0026 | 0.0112 | 0.0026 | 0.0067 | 0.0211 | 0.0315 | 0.0554 | 0.1393 | 0.1135 | 0.1685 | 0.1821 | 0.0921 | 0.1055 | 0.1573 | 0.1293 | 0.3933 | 0.3879 | 0.0000 | 0.0040 | 0.0140 | 0.0460 | 0.1180 | 0.1560 | 0.0960 | 0.1540 | 0.4120 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 854 | 416 | | 11131 | 15417 | 454.3 | 71.88 | 90.38 | 157.98 | 358 | 393 | 418 | 438 | 454 | 468 | 484 | 508 | 549 | 0.0688 | 1061 | 1.159 | 147.22 | 49.48 | 2 | 0.0314 | 350 | 0.0013 | 17.13 | 6.964 | 0.2615 | 211570.0 | 101000000 | 49300000000 | 24600000000000 | 0.4019 | 0.2435 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0025 | 0.0005 | 0.0056 | 0.0007 | 0.0198 | 0.0107 | 0.0364 | 0.0188 | 0.0370 | 0.0124 | 0.0542 | 0.0178 | 0.8429 | 0.9388 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0000 | 0.0023 | 0.0002 | 0.0110 | 0.0093 | 0.0213 | 0.0169 | 0.0198 | 0.0089 | 0.0278 | 0.0138 | 0.9153 | 0.9509 | 0.0058 | 0.0159 | 0.0075 | 0.0397 | 0.0100 | 0.0556 | 0.0325 | 0.1270 | 0.0600 | 0.0873 | 0.0783 | 0.1349 | 0.0666 | 0.1111 | 0.0966 | 0.0952 | 0.6428 | 0.3333 | 0.0012 | 0.0023 | 0.0068 | 0.0178 | 0.0371 | 0.0570 | 0.0697 | 0.0892 | 0.7189 | 7 | 9 | 10 | 11 | 14 | 23 | 53 | 139 | 311 | 0.2296 | 12.11 | 3.590 | 0.7091 | 33126.6 | 17600000 | 11100000000 | 7920000000000 | 0.5835 | 0.1060 | 0.0228 | 0.0066 | 0.0791 | 0.0185 | 0.1263 | 0.0524 | 0.1948 | 0.0739 | 0.1933 | 0.1344 | 0.1522 | 0.1839 | 0.0898 | 0.1440 | 0.0883 | 0.1322 | 0.0533 | 0.2541 | 0.0000 | 0.0006 | 0.0012 | 0.0017 | 0.0021 | 0.0039 | 0.0062 | 0.0067 | 0.0321 | 0.0323 | 0.0482 | 0.0424 | 0.0349 | 0.0336 | 0.0634 | 0.0528 | 0.8120 | 0.8259 | 0.0011 | 0.0003 | 0.0031 | 0.0018 | 0.0025 | 0.0028 | 0.0098 | 0.0104 | 0.0419 | 0.0429 | 0.0613 | 0.0726 | 0.0526 | 0.0643 | 0.0793 | 0.0867 | 0.7482 | 0.7182 | 0.0003 | 0.0013 | 0.0028 | 0.0103 | 0.0339 | 0.0573 | 0.0419 | 0.0637 | 0.7885 |
| SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 532 | 476 | | 5219 | 14862 | 435.3 | 124.40 | 337.57 | 481.74 | 232 | 330 | 406 | 440 | 463 | 485 | 504 | 529 | 568 | 0.0615 | 914 | 1.000 | 128.22 | 48.33 | 2 | 0.0674 | 352 | 0.0008 | 45.97 | 7.490 | 0.1610 | 204925.0 | 101000000 | 51900000000 | 27400000000000 | 0.3800 | 0.2460 | 0.0003 | 0.0000 | 0.0010 | 0.0000 | 0.0028 | 0.0002 | 0.0186 | 0.0019 | 0.0502 | 0.0190 | 0.0908 | 0.0389 | 0.0881 | 0.0283 | 0.1132 | 0.0482 | 0.6350 | 0.8635 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0009 | 0.0137 | 0.0123 | 0.0238 | 0.0237 | 0.0137 | 0.0121 | 0.0218 | 0.0185 | 0.9249 | 0.9326 | 0.0043 | 0.0084 | 0.0077 | 0.0422 | 0.0163 | 0.0253 | 0.0463 | 0.0633 | 0.0891 | 0.1266 | 0.1380 | 0.2194 | 0.1157 | 0.1181 | 0.1302 | 0.1646 | 0.4524 | 0.2321 | 0.0000 | 0.0000 | 0.0015 | 0.0080 | 0.0250 | 0.0367 | 0.0598 | 0.0712 | 0.7979 | 11 | 14 | 20 | 38 | 87 | 185 | 377 | 650 | 1059 | 0.0509 | 117.91 | 5.882 | 0.4621 | 346014.0 | 476000000 | 763000000000 | 1.34E+15 | 0.4474 | 0.1983 | 0.0233 | 0.0011 | 0.1329 | 0.0091 | 0.3034 | 0.0582 | 0.1982 | 0.0988 | 0.1639 | 0.2045 | 0.0941 | 0.2654 | 0.0532 | 0.1442 | 0.0199 | 0.1116 | 0.0111 | 0.1073 | 0.0000 | 0.0003 | 0.0002 | 0.0009 | 0.0017 | 0.0007 | 0.0048 | 0.0049 | 0.0457 | 0.0381 | 0.0817 | 0.0764 | 0.0489 | 0.0433 | 0.0740 | 0.0659 | 0.7430 | 0.7695 | 0.0002 | 0.0003 | 0.0007 | 0.0008 | 0.0019 | 0.0033 | 0.0107 | 0.0121 | 0.0534 | 0.0598 | 0.0963 | 0.1052 | 0.0590 | 0.0678 | 0.0919 | 0.0965 | 0.6858 | 0.6543 | 0.0000 | 0.0008 | 0.0017 | 0.0079 | 0.0480 | 0.0926 | 0.0499 | 0.0801 | 0.7189 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 994 | 366 | | 5578 | 9502 | 439.0 | 109.23 | 7.27 | 7.81 | 292 | 342 | 380 | 410 | 440 | 471 | 499 | 532 | 577 | 0.0764 | 726 | 0.939 | 87.10 | 28.18 | 1 | 0.0446 | 249 | 0.0007 | 54.37 | 7.463 | 0.1610 | 204683.0 | 101000000 | 51800000000 | 27900000000000 | 0.4190 | 0.2212 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0035 | 0.0004 | 0.0227 | 0.0026 | 0.0796 | 0.0200 | 0.1332 | 0.0381 | 0.1486 | 0.0495 | 0.1674 | 0.0707 | 0.4438 | 0.8187 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0009 | 0.0004 | 0.0055 | 0.0021 | 0.0249 | 0.0145 | 0.0386 | 0.0203 | 0.0420 | 0.0202 | 0.0598 | 0.0259 | 0.8277 | 0.9167 | 0.0025 | 0.0150 | 0.0083 | 0.0300 | 0.0108 | 0.0936 | 0.0717 | 0.1685 | 0.1350 | 0.1648 | 0.1983 | 0.1985 | 0.1250 | 0.0749 | 0.1433 | 0.0599 | 0.3050 | 0.1948 | 0.0011 | 0.0014 | 0.0018 | 0.0164 | 0.0513 | 0.0969 | 0.0840 | 0.1033 | 0.6439 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 10 | 0.3430 | 0.51 | 1.198 | 0.7294 | 113.9 | 6884.51 | 785459 | 106000000 | 0.5832 | 0.1225 | 0.0192 | 0.0019 | 0.0770 | 0.0156 | 0.1579 | 0.0462 | 0.2263 | 0.1039 | 0.2280 | 0.1979 | 0.1695 | 0.2473 | 0.0885 | 0.2176 | 0.0290 | 0.1308 | 0.0047 | 0.0389 | 0.0061 | 0.0001 | 0.0245 | 0.0052 | 0.0678 | 0.0214 | 0.1121 | 0.0524 | 0.1595 | 0.1246 | 0.1671 | 0.1799 | 0.1649 | 0.2137 | 0.1572 | 0.2103 | 0.1408 | 0.1925 | 0.1745 | 0.1950 | 0.1707 | 0.1376 | 0.1329 | 0.1217 | 0.1097 | 0.1088 | 0.0929 | 0.0945 | 0.0843 | 0.0801 | 0.0659 | 0.0748 | 0.0751 | 0.0786 | 0.0940 | 0.1088 | 0.0231 | 0.0695 | 0.1299 | 0.1560 | 0.1619 | 0.1493 | 0.1157 | 0.0965 | 0.0981 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 209 | 570 | | 4703 | 11257 | 455.0 | 77.10 | 137.18 | 277.92 | 340 | 398 | 427 | 444 | 459 | 475 | 493 | 516 | 549 | 0.0636 | 716 | 0.833 | 89.36 | 25.02 | 3 | 0.0515 | 242 | 0.0019 | 16.09 | 6.616 | 0.2886 | 212933.0 | 102000000 | 50100000000 | 25100000000000 | 0.4498 | 0.1891 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0011 | 0.0002 | 0.0053 | 0.0006 | 0.0283 | 0.0153 | 0.0415 | 0.0267 | 0.0404 | 0.0162 | 0.0569 | 0.0265 | 0.8258 | 0.9144 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0006 | 0.0175 | 0.0150 | 0.0253 | 0.0249 | 0.0212 | 0.0146 | 0.0305 | 0.0226 | 0.9033 | 0.9222 | 0.0040 | 0.0000 | 0.0120 | 0.1429 | 0.0080 | 0.2143 | 0.0300 | 0.1429 | 0.0580 | 0.2857 | 0.0920 | 0.1429 | 0.0820 | 0.0714 | 0.0900 | 0.0000 | 0.6240 | 0.0000 | 0.0032 | 0.0069 | 0.0105 | 0.0242 | 0.0395 | 0.0492 | 0.0629 | 0.0786 | 0.7251 | 9 | 11 | 13 | 15 | 18 | 27 | 60 | 180 | 452 | 0.1894 | 29.54 | 3.820 | 0.6610 | 96051.8 | 107000000 | 152000000000 | 257000000000000 | 0.3706 | 0.2754 | 0.0734 | 0.0034 | 0.1353 | 0.0339 | 0.2638 | 0.1141 | 0.1789 | 0.1548 | 0.1628 | 0.1390 | 0.0757 | 0.1921 | 0.0436 | 0.1209 | 0.0367 | 0.1028 | 0.0298 | 0.1390 | 0.0004 | 0.0000 | 0.0007 | 0.0010 | 0.0032 | 0.0010 | 0.0140 | 0.0094 | 0.0415 | 0.0439 | 0.0727 | 0.0638 | 0.0466 | 0.0449 | 0.0659 | 0.0651 | 0.7550 | 0.7708 | 0.0000 | 0.0000 | 0.0034 | 0.0014 | 0.0038 | 0.0027 | 0.0089 | 0.0119 | 0.0539 | 0.0562 | 0.0883 | 0.0965 | 0.0526 | 0.0562 | 0.0870 | 0.0942 | 0.7020 | 0.6808 | 0.0004 | 0.0012 | 0.0019 | 0.0105 | 0.0487 | 0.0790 | 0.0487 | 0.0821 | 0.7275 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1092 | 85 | | 5449 | 11450 | 95.0 | 23.16 | 86.45 | 60.42 | 71 | 77 | 81 | 86 | 91 | 95 | 101 | 110 | 125 | 0.0779 | 892 | 0.747 | 88.84 | 18.03 | 1 | 0.0376 | 205 | 0.0045 | 11.97 | 5.782 | 0.3166 | 9560.2 | 1030000 | 119000000 | 14900000000 | 0.4517 | 0.1982 | 0.0017 | 0.0000 | 0.0031 | 0.0000 | 0.0068 | 0.0002 | 0.0214 | 0.0018 | 0.0749 | 0.0225 | 0.1219 | 0.0393 | 0.1611 | 0.0466 | 0.2022 | 0.0826 | 0.4069 | 0.8069 | 0.0013 | 0.0000 | 0.0016 | 0.0000 | 0.0029 | 0.0000 | 0.0120 | 0.0006 | 0.0334 | 0.0144 | 0.0484 | 0.0215 | 0.0776 | 0.0164 | 0.1074 | 0.0354 | 0.7154 | 0.9118 | 0.0096 | 0.0216 | 0.0160 | 0.0377 | 0.0310 | 0.0377 | 0.0652 | 0.0970 | 0.1485 | 0.1375 | 0.1485 | 0.1563 | 0.1239 | 0.1186 | 0.1528 | 0.1456 | 0.3045 | 0.2480 | 0.0022 | 0.0066 | 0.0254 | 0.0521 | 0.0902 | 0.1139 | 0.1248 | 0.1323 | 0.4525 | 21 | 33 | 45 | 59 | 73 | 90 | 110 | 133 | 169 | 0.0064 | 12.20 | 5.702 | 0.3894 | 11125.0 | 1840000 | 360000000 | 80100000000 | 0.5551 | 0.1175 | 0.0169 | 0.0024 | 0.0852 | 0.0089 | 0.1933 | 0.0316 | 0.2046 | 0.0842 | 0.1860 | 0.1444 | 0.1445 | 0.1944 | 0.0848 | 0.1671 | 0.0580 | 0.1675 | 0.0268 | 0.1994 | 0.0005 | 0.0011 | 0.0025 | 0.0020 | 0.0062 | 0.0051 | 0.0237 | 0.0164 | 0.0697 | 0.0496 | 0.1043 | 0.0775 | 0.0994 | 0.0776 | 0.1410 | 0.1147 | 0.5528 | 0.6561 | 0.0008 | 0.0052 | 0.0066 | 0.0098 | 0.0138 | 0.0265 | 0.0517 | 0.0622 | 0.1115 | 0.1306 | 0.1502 | 0.1614 | 0.1351 | 0.1383 | 0.1523 | 0.1453 | 0.3780 | 0.3206 | 0.0019 | 0.0031 | 0.0080 | 0.0331 | 0.0932 | 0.1245 | 0.1171 | 0.1566 | 0.4623 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1120 | 374 | | 1013 | 7639 | 932.9 | 280.82 | 18.77 | 68.99 | 520 | 632 | 745 | 866 | 972 | 1068 | 1154 | 1217 | 1274 | 0.0730 | 558 | 0.951 | 63.01 | 16.64 | 2 | 0.1382 | 140 | 0.0016 | 66.58 | 6.568 | 0.1620 | 949022.0 | 1030000000 | 1160000000000 | 1.34E+15 | 0.2997 | 0.3332 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0028 | 0.0013 | 0.0141 | 0.0025 | 0.1155 | 0.0401 | 0.2197 | 0.0877 | 0.1380 | 0.0401 | 0.1662 | 0.0677 | 0.3437 | 0.7607 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0042 | 0.0000 | 0.0368 | 0.0311 | 0.0637 | 0.0681 | 0.0326 | 0.0219 | 0.0425 | 0.0381 | 0.8201 | 0.8408 | 0.0000 | 0.0000 | 0.0000 | 0.0145 | 0.0000 | 0.0000 | 0.0171 | 0.0580 | 0.0484 | 0.1449 | 0.0883 | 0.1014 | 0.0570 | 0.1014 | 0.0712 | 0.2029 | 0.7179 | 0.3768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0427 | 0.0816 | 0.0278 | 0.0594 | 0.7885 | 4 | 5 | 6 | 6 | 8 | 8 | 9 | 11 | 13 | 0.1323 | 2.99 | 1.460 | 0.4553 | 5111.7 | 3110000 | 2280000000 | 1870000000000 | 0.4103 | 0.1711 | 0.2687 | 0.1623 | 0.2463 | 0.1455 | 0.2015 | 0.1545 | 0.2612 | 0.1636 | 0.0224 | 0.1325 | 0.0000 | 0.1273 | 0.0000 | 0.0688 | 0.0000 | 0.0416 | 0.0000 | 0.0039 | 0.0357 | 0.1050 | 0.0187 | 0.0915 | 0.0221 | 0.0882 | 0.0306 | 0.0747 | 0.0629 | 0.0571 | 0.0510 | 0.0756 | 0.0952 | 0.0655 | 0.0799 | 0.0756 | 0.6037 | 0.3669 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0066 | 0.0000 | 0.0176 | 0.0143 | 0.0683 | 0.0903 | 0.1101 | 0.1021 | 0.0551 | 0.0570 | 0.0991 | 0.1069 | 0.6410 | 0.6295 | 0.0100 | 0.0060 | 0.0040 | 0.0260 | 0.0680 | 0.0820 | 0.0740 | 0.0900 | 0.6400 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 402 | 136 | | 3297 | 12148 | 98.0 | 18.33 | 8.19 | 2.60 | 74 | 80 | 85 | 92 | 97 | 103 | 108 | 114 | 123 | 0.0740 | 899 | 0.685 | 83.76 | 26.42 | 1 | 0.0746 | 246 | 0.0399 | 0.86 | 3.490 | 0.6974 | 9940.2 | 1040000 | 113000000 | 12600000000 | 0.4461 | 0.1984 | 0.0050 | 0.0003 | 0.0077 | 0.0000 | 0.0149 | 0.0019 | 0.0398 | 0.0046 | 0.0430 | 0.0207 | 0.0742 | 0.0377 | 0.0972 | 0.0303 | 0.1470 | 0.0585 | 0.5712 | 0.8460 | 0.0026 | 0.0000 | 0.0018 | 0.0000 | 0.0048 | 0.0015 | 0.0183 | 0.0033 | 0.0202 | 0.0176 | 0.0352 | 0.0303 | 0.0421 | 0.0218 | 0.0546 | 0.0331 | 0.8204 | 0.8923 | 0.0251 | 0.0625 | 0.0309 | 0.0625 | 0.0502 | 0.1719 | 0.0598 | 0.1563 | 0.0927 | 0.1875 | 0.1544 | 0.1406 | 0.1216 | 0.0938 | 0.1564 | 0.0781 | 0.3089 | 0.0469 | 0.0024 | 0.0036 | 0.0134 | 0.0243 | 0.0389 | 0.0584 | 0.0833 | 0.1217 | 0.6539 | 5 | 6 | 7 | 7 | 8 | 9 | 9 | 10 | 12 | 0.0144 | 12.37 | 4.643 | 0.3155 | 73.9 | 721.847 | 7566.38 | 84525.8 | 0.5238 | 0.1413 | 0.0153 | 0.0002 | 0.0771 | 0.0016 | 0.1639 | 0.0070 | 0.2274 | 0.0223 | 0.2309 | 0.0551 | 0.1655 | 0.1102 | 0.0864 | 0.1993 | 0.0283 | 0.3127 | 0.0052 | 0.2916 | 0.0011 | 0.0000 | 0.0072 | 0.0003 | 0.0296 | 0.0015 | 0.0604 | 0.0068 | 0.1020 | 0.0189 | 0.1625 | 0.0400 | 0.2241 | 0.0871 | 0.2509 | 0.2788 | 0.1621 | 0.5666 | 0.0905 | 0.3211 | 0.1651 | 0.2629 | 0.2052 | 0.1761 | 0.1949 | 0.1076 | 0.1565 | 0.0717 | 0.0987 | 0.0351 | 0.0583 | 0.0215 | 0.0222 | 0.0032 | 0.0085 | 0.0008 | 0.0051 | 0.0284 | 0.0735 | 0.1320 | 0.1649 | 0.1938 | 0.1874 | 0.1443 | 0.0706 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 958 | 125 | | 2932 | 10604 | 196.6 | 65.96 | 9.01 | 4.41 | 127 | 138 | 150 | 164 | 179 | 198 | 223 | 249 | 301 | 0.0658 | 698 | 0.614 | 76.01 | 21.95 | 1 | 0.0836 | 245 | 0.0079 | 2.74 | 5.180 | 0.5006 | 42980.6 | 10400000 | 2760000000 | 788000000000 | 0.4076 | 0.2304 | 0.0043 | 0.0013 | 0.0035 | 0.0013 | 0.0112 | 0.0042 | 0.0371 | 0.0097 | 0.0569 | 0.0295 | 0.1320 | 0.0687 | 0.1217 | 0.0442 | 0.1639 | 0.0720 | 0.4694 | 0.7692 | 0.0021 | 0.0011 | 0.0021 | 0.0007 | 0.0053 | 0.0032 | 0.0137 | 0.0064 | 0.0217 | 0.0207 | 0.0455 | 0.0454 | 0.0418 | 0.0264 | 0.0561 | 0.0482 | 0.8117 | 0.8477 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0109 | 0.0047 | 0.0301 | 0.0165 | 0.0342 | 0.0425 | 0.0861 | 0.0778 | 0.0697 | 0.0472 | 0.0765 | 0.0802 | 0.6899 | 0.7311 | 0.0017 | 0.0025 | 0.0042 | 0.0151 | 0.0260 | 0.0519 | 0.0511 | 0.0611 | 0.7864 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 14 | 0.0111 | 13.72 | 5.076 | 0.3038 | 100.7 | 1416.1 | 25055.2 | 539238 | 0.4587 | 0.1802 | 0.0400 | 0.0040 | 0.1247 | 0.0070 | 0.2092 | 0.0206 | 0.2582 | 0.0465 | 0.1991 | 0.1010 | 0.1141 | 0.1792 | 0.0447 | 0.2550 | 0.0098 | 0.2595 | 0.0003 | 0.1273 | 0.0087 | 0.0002 | 0.0392 | 0.0012 | 0.0841 | 0.0078 | 0.1282 | 0.0233 | 0.1444 | 0.0654 | 0.1470 | 0.1201 | 0.1169 | 0.1781 | 0.1209 | 0.2377 | 0.2107 | 0.3662 | 0.1147 | 0.1071 | 0.0900 | 0.0750 | 0.0862 | 0.0679 | 0.0718 | 0.0968 | 0.0938 | 0.0859 | 0.1045 | 0.1000 | 0.0836 | 0.1019 | 0.0957 | 0.1167 | 0.2595 | 0.2487 | 0.0483 | 0.0956 | 0.1102 | 0.1089 | 0.1085 | 0.0986 | 0.0902 | 0.1128 | 0.2269 |
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1104 | 606 | | 7792 | 17317 | 455.1 | 84.64 | 91.04 | 159.85 | 350 | 380 | 405 | 428 | 449 | 472 | 497 | 528 | 568 | 0.0587 | 1017 | 0.843 | 136.49 | 39.96 | 1 | 0.0508 | 396 | 0.0009 | 41.02 | 7.256 | 0.1774 | 214248.0 | 104000000 | 52400000000 | 27200000000000 | 0.4390 | 0.2040 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0038 | 0.0000 | 0.0136 | 0.0005 | 0.0498 | 0.0107 | 0.1097 | 0.0237 | 0.1108 | 0.0193 | 0.1486 | 0.0344 | 0.5627 | 0.9113 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0024 | 0.0000 | 0.0058 | 0.0004 | 0.0229 | 0.0095 | 0.0478 | 0.0189 | 0.0484 | 0.0112 | 0.0635 | 0.0227 | 0.8089 | 0.9373 | 0.0050 | 0.0153 | 0.0059 | 0.0153 | 0.0243 | 0.0458 | 0.0703 | 0.1756 | 0.1456 | 0.1221 | 0.1816 | 0.1603 | 0.1364 | 0.0916 | 0.1356 | 0.1069 | 0.2954 | 0.2672 | 0.0019 | 0.0038 | 0.0059 | 0.0261 | 0.0676 | 0.1051 | 0.0997 | 0.1070 | 0.5829 | 5 | 6 | 7 | 9 | 11 | 25 | 76 | 148 | 295 | 0.1599 | 22.17 | 4.036 | 0.5973 | 33837.1 | 18800000 | 12800000000 | 9900000000000 | 0.6360 | 0.0673 | 0.0357 | 0.0021 | 0.1417 | 0.0167 | 0.2200 | 0.0889 | 0.1536 | 0.1271 | 0.1497 | 0.1836 | 0.1249 | 0.1857 | 0.0694 | 0.1130 | 0.0565 | 0.1130 | 0.0486 | 0.1700 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0006 | 0.0003 | 0.0113 | 0.0062 | 0.0430 | 0.0382 | 0.0708 | 0.0689 | 0.0549 | 0.0430 | 0.0815 | 0.0753 | 0.7371 | 0.7679 | 0.0002 | 0.0000 | 0.0005 | 0.0010 | 0.0049 | 0.0052 | 0.0117 | 0.0160 | 0.0608 | 0.0640 | 0.0963 | 0.1006 | 0.0629 | 0.0694 | 0.0974 | 0.1091 | 0.6653 | 0.6349 | 0.0002 | 0.0006 | 0.0023 | 0.0121 | 0.0489 | 0.0886 | 0.0606 | 0.0917 | 0.6949 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 935 | 650 | | 4467 | 9610 | 94.8 | 24.92 | 207.00 | 159.98 | 69 | 75 | 80 | 84 | 89 | 95 | 102 | 111 | 128 | 0.0728 | 700 | 0.935 | 58.80 | 21.38 | 2 | 0.0374 | 167 | 0.0023 | 22.65 | 6.438 | 0.2515 | 9610.2 | 1050000 | 124000000 | 15700000000 | 0.4444 | 0.2134 | 0.0007 | 0.0000 | 0.0055 | 0.0010 | 0.0092 | 0.0005 | 0.0283 | 0.0039 | 0.0881 | 0.0217 | 0.1418 | 0.0440 | 0.1686 | 0.0426 | 0.1851 | 0.0733 | 0.3728 | 0.8130 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0048 | 0.0000 | 0.0127 | 0.0016 | 0.0469 | 0.0122 | 0.0720 | 0.0228 | 0.0813 | 0.0176 | 0.1042 | 0.0375 | 0.6764 | 0.9083 | 0.0098 | 0.0137 | 0.0147 | 0.0000 | 0.0244 | 0.0192 | 0.0452 | 0.0658 | 0.1345 | 0.1699 | 0.1516 | 0.2000 | 0.1186 | 0.1151 | 0.1528 | 0.1699 | 0.3484 | 0.2466 | 0.0039 | 0.0055 | 0.0171 | 0.0473 | 0.0892 | 0.1244 | 0.1007 | 0.1172 | 0.4948 | 54 | 84 | 111 | 137 | 168 | 203 | 242 | 303 | 400 | 0.0032 | 28.25 | 6.373 | 0.3196 | 68440.7 | 32700000 | 20600000000 | 15800000000000 | 0.5401 | 0.1476 | 0.0155 | 0.0007 | 0.0447 | 0.0007 | 0.1182 | 0.0190 | 0.1771 | 0.0542 | 0.2087 | 0.1259 | 0.1908 | 0.1667 | 0.1258 | 0.1621 | 0.0810 | 0.1828 | 0.0382 | 0.2878 | 0.0008 | 0.0002 | 0.0010 | 0.0003 | 0.0045 | 0.0026 | 0.0207 | 0.0082 | 0.0649 | 0.0465 | 0.1107 | 0.0798 | 0.0944 | 0.0796 | 0.1265 | 0.1118 | 0.5765 | 0.6712 | 0.0018 | 0.0019 | 0.0080 | 0.0062 | 0.0123 | 0.0162 | 0.0355 | 0.0380 | 0.0952 | 0.1102 | 0.1509 | 0.1501 | 0.0955 | 0.1083 | 0.1404 | 0.1406 | 0.4604 | 0.4285 | 0.0005 | 0.0013 | 0.0099 | 0.0259 | 0.0863 | 0.1255 | 0.0978 | 0.1408 | 0.5120 |
| BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1011 | 503 | | 8099 | 27715 | 207.4 | 49.29 | 90.32 | 133.45 | 151 | 164 | 175 | 187 | 199 | 212 | 228 | 248 | 276 | 0.0437 | 1212 | 1.109 | 152.01 | 45.19 | 2 | 0.0436 | 353 | 0.0011 | 36.08 | 7.089 | 0.1990 | 45423.4 | 10500000 | 2560000000 | 657000000000 | 0.4089 | 0.2364 | 0.0004 | 0.0000 | 0.0023 | 0.0001 | 0.0071 | 0.0004 | 0.0235 | 0.0021 | 0.0760 | 0.0188 | 0.1336 | 0.0422 | 0.1525 | 0.0391 | 0.1806 | 0.0611 | 0.4239 | 0.8362 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0033 | 0.0001 | 0.0108 | 0.0006 | 0.0290 | 0.0107 | 0.0546 | 0.0216 | 0.0625 | 0.0137 | 0.0784 | 0.0235 | 0.7599 | 0.9297 | 0.0031 | 0.0101 | 0.0081 | 0.0067 | 0.0219 | 0.0236 | 0.0663 | 0.0809 | 0.1006 | 0.1720 | 0.1644 | 0.1585 | 0.1294 | 0.1282 | 0.1413 | 0.1619 | 0.3650 | 0.2580 | 0.0019 | 0.0022 | 0.0111 | 0.0259 | 0.0674 | 0.1078 | 0.1033 | 0.1236 | 0.5567 | 7 | 8 | 10 | 11 | 15 | 35 | 93 | 181 | 284 | 0.1964 | 12.37 | 4.050 | 0.6366 | 25966.7 | 10500000 | 5130000000 | 2920000000000 | 0.4760 | 0.1582 | 0.0839 | 0.0025 | 0.2737 | 0.0194 | 0.3606 | 0.1699 | 0.1380 | 0.2452 | 0.0745 | 0.2308 | 0.0467 | 0.1602 | 0.0182 | 0.0849 | 0.0044 | 0.0541 | 0.0000 | 0.0330 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0003 | 0.0003 | 0.0065 | 0.0072 | 0.0442 | 0.0379 | 0.0776 | 0.0649 | 0.0515 | 0.0468 | 0.0806 | 0.0673 | 0.7388 | 0.7756 | 0.0000 | 0.0001 | 0.0003 | 0.0006 | 0.0004 | 0.0007 | 0.0094 | 0.0113 | 0.0554 | 0.0601 | 0.1006 | 0.1144 | 0.0720 | 0.0756 | 0.1022 | 0.1029 | 0.6597 | 0.6343 | 0.0001 | 0.0000 | 0.0006 | 0.0064 | 0.0501 | 0.0888 | 0.0621 | 0.0936 | 0.6982 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 260 | 906 | | 6741 | 5810 | 457.5 | 85.03 | 189.24 | 346.87 | 354 | 397 | 434 | 457 | 471 | 484 | 497 | 515 | 542 | 0.1139 | 662 | 0.726 | 107.34 | 27.78 | 4 | 0.0481 | 324 | 0.0013 | 28.66 | 7.062 | 0.2336 | 216541.0 | 105000000 | 52100000000 | 26300000000000 | 0.4404 | 0.2127 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0038 | 0.0000 | 0.0072 | 0.0011 | 0.0244 | 0.0142 | 0.0415 | 0.0371 | 0.0385 | 0.0169 | 0.0651 | 0.0290 | 0.8182 | 0.9017 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0026 | 0.0000 | 0.0044 | 0.0005 | 0.0175 | 0.0138 | 0.0303 | 0.0338 | 0.0218 | 0.0135 | 0.0322 | 0.0208 | 0.8903 | 0.9176 | 0.0174 | 0.0000 | 0.0209 | 0.0000 | 0.0192 | 0.0000 | 0.0314 | 0.0000 | 0.0401 | 0.0000 | 0.0627 | 0.0000 | 0.0592 | 0.0000 | 0.0941 | 0.0000 | 0.6551 | 0.0000 | 0.0007 | 0.0045 | 0.0057 | 0.0172 | 0.0314 | 0.0528 | 0.0617 | 0.0889 | 0.7372 | 15 | 17 | 18 | 21 | 27 | 55 | 114 | 280 | 602 | 0.2435 | 18.42 | 3.549 | 0.6966 | 156109.0 | 197000000 | 310000000000 | 567000000000000 | 0.6374 | 0.0658 | 0.0763 | 0.0000 | 0.1968 | 0.0329 | 0.2129 | 0.1024 | 0.1566 | 0.1225 | 0.1406 | 0.1846 | 0.1245 | 0.1554 | 0.0482 | 0.1280 | 0.0361 | 0.1188 | 0.0080 | 0.1554 | 0.0013 | 0.0000 | 0.0019 | 0.0006 | 0.0039 | 0.0023 | 0.0142 | 0.0138 | 0.0685 | 0.0619 | 0.0931 | 0.0865 | 0.0672 | 0.0613 | 0.1002 | 0.0980 | 0.6496 | 0.6756 | 0.0008 | 0.0000 | 0.0031 | 0.0025 | 0.0046 | 0.0067 | 0.0208 | 0.0200 | 0.0701 | 0.0835 | 0.1017 | 0.0943 | 0.0770 | 0.0760 | 0.1063 | 0.1077 | 0.6156 | 0.6093 | 0.0000 | 0.0014 | 0.0043 | 0.0157 | 0.0686 | 0.1029 | 0.0657 | 0.1064 | 0.6350 |
| BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 603 | 689 | | 7600 | 15811 | 210.9 | 43.78 | 142.17 | 171.25 | 159 | 173 | 185 | 196 | 207 | 218 | 230 | 245 | 269 | 0.0623 | 985 | 1.140 | 88.32 | 39.01 | 1 | 0.0330 | 251 | 0.0011 | 39.63 | 7.083 | 0.1887 | 46382.0 | 10600000 | 2540000000 | 632000000000 | 0.4649 | 0.1876 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0031 | 0.0000 | 0.0156 | 0.0013 | 0.0581 | 0.0167 | 0.1363 | 0.0365 | 0.1516 | 0.0327 | 0.1761 | 0.0584 | 0.4584 | 0.8545 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0074 | 0.0004 | 0.0307 | 0.0110 | 0.0643 | 0.0228 | 0.0646 | 0.0137 | 0.0939 | 0.0247 | 0.7375 | 0.9274 | 0.0050 | 0.0238 | 0.0058 | 0.0149 | 0.0284 | 0.0387 | 0.0984 | 0.1310 | 0.1418 | 0.1786 | 0.1818 | 0.1994 | 0.0992 | 0.1012 | 0.1276 | 0.1250 | 0.3119 | 0.1875 | 0.0009 | 0.0020 | 0.0111 | 0.0386 | 0.0873 | 0.1384 | 0.1199 | 0.1335 | 0.4684 | 11 | 13 | 15 | 21 | 53 | 120 | 192 | 279 | 392 | 0.0646 | 26.36 | 5.217 | 0.4922 | 49534.8 | 23000000 | 12600000000 | 7870000000000 | 0.5544 | 0.1062 | 0.0575 | 0.0021 | 0.2553 | 0.0185 | 0.3274 | 0.1627 | 0.1596 | 0.1906 | 0.0883 | 0.1964 | 0.0624 | 0.1886 | 0.0300 | 0.1011 | 0.0130 | 0.0719 | 0.0065 | 0.0682 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0005 | 0.0010 | 0.0079 | 0.0052 | 0.0517 | 0.0451 | 0.0963 | 0.0833 | 0.0703 | 0.0593 | 0.0991 | 0.0835 | 0.6739 | 0.7223 | 0.0002 | 0.0004 | 0.0013 | 0.0015 | 0.0029 | 0.0043 | 0.0140 | 0.0201 | 0.0689 | 0.0788 | 0.1235 | 0.1391 | 0.0936 | 0.0936 | 0.1214 | 0.1176 | 0.5743 | 0.5445 | 0.0000 | 0.0003 | 0.0017 | 0.0095 | 0.0610 | 0.1104 | 0.0758 | 0.1149 | 0.6263 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1033 | 712 | | 5129 | 6293 | 97.3 | 21.87 | 101.52 | 63.35 | 73 | 79 | 84 | 89 | 94 | 99 | 105 | 113 | 127 | 0.1198 | 754 | 1.045 | 82.39 | 32.89 | 1 | 0.0454 | 233 | 0.0050 | 8.89 | 5.676 | 0.3565 | 9951.5 | 1070000 | 122000000 | 14600000000 | 0.4238 | 0.2335 | 0.0015 | 0.0002 | 0.0027 | 0.0006 | 0.0094 | 0.0006 | 0.0277 | 0.0027 | 0.0690 | 0.0239 | 0.1298 | 0.0420 | 0.1351 | 0.0409 | 0.1808 | 0.0709 | 0.4441 | 0.8180 | 0.0009 | 0.0000 | 0.0014 | 0.0002 | 0.0042 | 0.0004 | 0.0117 | 0.0006 | 0.0391 | 0.0163 | 0.0615 | 0.0248 | 0.0667 | 0.0163 | 0.1036 | 0.0330 | 0.7109 | 0.9084 | 0.0057 | 0.0123 | 0.0181 | 0.0370 | 0.0294 | 0.0216 | 0.0611 | 0.0957 | 0.1041 | 0.1698 | 0.1561 | 0.1698 | 0.1210 | 0.1327 | 0.1493 | 0.1481 | 0.3552 | 0.2130 | 0.0022 | 0.0075 | 0.0141 | 0.0435 | 0.0804 | 0.1094 | 0.1094 | 0.1313 | 0.5024 | 30 | 47 | 61 | 73 | 88 | 104 | 126 | 153 | 191 | 0.0033 | 26.60 | 6.249 | 0.2945 | 14318.5 | 2510000 | 508000000 | 114000000000 | 0.5313 | 0.1551 | 0.0099 | 0.0024 | 0.0992 | 0.0097 | 0.1686 | 0.0286 | 0.1523 | 0.0721 | 0.1856 | 0.1352 | 0.1664 | 0.1776 | 0.1126 | 0.1579 | 0.0729 | 0.1655 | 0.0326 | 0.2510 | 0.0006 | 0.0002 | 0.0044 | 0.0016 | 0.0050 | 0.0032 | 0.0174 | 0.0114 | 0.0636 | 0.0473 | 0.1271 | 0.0905 | 0.1043 | 0.0864 | 0.1315 | 0.1093 | 0.5460 | 0.6500 | 0.0010 | 0.0014 | 0.0051 | 0.0095 | 0.0112 | 0.0265 | 0.0446 | 0.0522 | 0.1076 | 0.1255 | 0.1862 | 0.2171 | 0.1476 | 0.1452 | 0.1558 | 0.1567 | 0.3409 | 0.2659 | 0.0019 | 0.0023 | 0.0096 | 0.0266 | 0.0914 | 0.1450 | 0.1226 | 0.1546 | 0.4458 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1152 | 223 | | 1691 | 12352 | 99.2 | 17.11 | 46.92 | 69.30 | 79 | 84 | 88 | 92 | 96 | 101 | 107 | 114 | 124 | 0.0508 | 627 | 1.190 | 91.98 | 34.23 | 1 | 0.1366 | 231 | 0.0065 | 7.72 | 5.324 | 0.3702 | 10134.8 | 1070000 | 116000000 | 12900000000 | 0.3875 | 0.2575 | 0.0008 | 0.0000 | 0.0040 | 0.0000 | 0.0127 | 0.0000 | 0.0343 | 0.0024 | 0.0741 | 0.0253 | 0.1076 | 0.0519 | 0.1139 | 0.0404 | 0.1777 | 0.0821 | 0.4749 | 0.7978 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0047 | 0.0000 | 0.0206 | 0.0018 | 0.0419 | 0.0231 | 0.0599 | 0.0420 | 0.0573 | 0.0213 | 0.0879 | 0.0390 | 0.7264 | 0.8729 | 0.0121 | 0.1176 | 0.0040 | 0.1765 | 0.0526 | 0.2353 | 0.0931 | 0.2941 | 0.1336 | 0.1176 | 0.1903 | 0.0588 | 0.1579 | 0.0000 | 0.1741 | 0.0000 | 0.1822 | 0.0000 | 0.0039 | 0.0065 | 0.0310 | 0.0233 | 0.0802 | 0.1125 | 0.1035 | 0.1475 | 0.4916 | 7 | 10 | 13 | 17 | 23 | 32 | 44 | 64 | 112 | 0.0318 | 9.40 | 4.580 | 0.5581 | 7003.8 | 2350000 | 1290000000 | 919000000000 | 0.6011 | 0.1309 | 0.0239 | 0.0061 | 0.0710 | 0.0163 | 0.1253 | 0.0476 | 0.1857 | 0.0850 | 0.1744 | 0.1282 | 0.1459 | 0.1473 | 0.1187 | 0.1486 | 0.1054 | 0.1514 | 0.0497 | 0.2694 | 0.0028 | 0.0028 | 0.0058 | 0.0052 | 0.0106 | 0.0099 | 0.0311 | 0.0268 | 0.0659 | 0.0579 | 0.0954 | 0.0806 | 0.0809 | 0.0798 | 0.1143 | 0.1059 | 0.5934 | 0.6311 | 0.0056 | 0.0063 | 0.0141 | 0.0117 | 0.0159 | 0.0184 | 0.0286 | 0.0284 | 0.0766 | 0.0755 | 0.1048 | 0.1172 | 0.0886 | 0.0893 | 0.1172 | 0.1247 | 0.5485 | 0.5286 | 0.0026 | 0.0105 | 0.0228 | 0.0324 | 0.0762 | 0.0964 | 0.0836 | 0.1155 | 0.5599 | ||
| MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 517 | 209 | | 10942 | 35449 | 447.3 | 110.82 | 142.08 | 205.96 | 312 | 350 | 381 | 410 | 439 | 469 | 501 | 538 | 598 | 0.0363 | 1286 | 0.903 | 94.01 | 21.02 | 3 | 0.0206 | 225 | 0.0006 | 67.31 | 7.714 | 0.1503 | 212393.0 | 107000000 | 56200000000 | 31100000000000 | 0.4346 | 0.2214 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0003 | 0.0220 | 0.0020 | 0.0807 | 0.0222 | 0.1586 | 0.0494 | 0.1521 | 0.0568 | 0.1699 | 0.0831 | 0.4104 | 0.7861 | 0.0001 | 0.0000 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0069 | 0.0010 | 0.0331 | 0.0142 | 0.0664 | 0.0263 | 0.0584 | 0.0248 | 0.0766 | 0.0387 | 0.7570 | 0.8948 | 0.0022 | 0.0069 | 0.0081 | 0.0139 | 0.0103 | 0.0416 | 0.0550 | 0.1150 | 0.1279 | 0.1967 | 0.1699 | 0.1884 | 0.1225 | 0.1177 | 0.1516 | 0.1399 | 0.3524 | 0.1801 | 0.0008 | 0.0008 | 0.0065 | 0.0223 | 0.0687 | 0.1106 | 0.0929 | 0.1244 | 0.5730 | 7 | 10 | 12 | 15 | 24 | 71 | 163 | 276 | 443 | 0.1042 | 31.77 | 4.906 | 0.5483 | 62607.4 | 38100000 | 28100000000 | 23900000000000 | 0.4712 | 0.1726 | 0.0362 | 0.0022 | 0.1614 | 0.0112 | 0.2304 | 0.0744 | 0.1585 | 0.1487 | 0.1473 | 0.1922 | 0.1121 | 0.1786 | 0.0662 | 0.1198 | 0.0498 | 0.1135 | 0.0382 | 0.1594 | 0.0002 | 0.0001 | 0.0002 | 0.0002 | 0.0007 | 0.0005 | 0.0067 | 0.0061 | 0.0345 | 0.0311 | 0.0658 | 0.0530 | 0.0462 | 0.0389 | 0.0718 | 0.0600 | 0.7738 | 0.8102 | 0.0000 | 0.0005 | 0.0006 | 0.0007 | 0.0010 | 0.0021 | 0.0102 | 0.0107 | 0.0492 | 0.0560 | 0.0855 | 0.0946 | 0.0637 | 0.0738 | 0.0966 | 0.1019 | 0.6933 | 0.6595 | 0.0002 | 0.0003 | 0.0018 | 0.0074 | 0.0431 | 0.0740 | 0.0560 | 0.0876 | 0.7297 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 561 | 247 | | 4445 | 15033 | 466.1 | 65.09 | 63.62 | 138.06 | 379 | 413 | 433 | 450 | 466 | 481 | 499 | 521 | 551 | 0.0559 | 840 | 1.186 | 46.40 | 17.49 | 1 | 0.0270 | 120 | 0.0015 | 34.76 | 6.820 | 0.2169 | 221513.0 | 107000000 | 52800000000 | 26400000000000 | 0.4116 | 0.2311 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0035 | 0.0002 | 0.0355 | 0.0137 | 0.0646 | 0.0248 | 0.0635 | 0.0142 | 0.0910 | 0.0205 | 0.7407 | 0.9266 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0020 | 0.0002 | 0.0221 | 0.0137 | 0.0368 | 0.0248 | 0.0314 | 0.0142 | 0.0456 | 0.0187 | 0.8620 | 0.9284 | 0.0110 | 1.0000 | 0.0192 | 0.0000 | 0.0219 | 0.0000 | 0.0959 | 0.0000 | 0.1479 | 0.0000 | 0.1726 | 0.0000 | 0.1397 | 0.0000 | 0.1288 | 0.0000 | 0.2630 | 0.0000 | 0.0004 | 0.0036 | 0.0085 | 0.0278 | 0.0732 | 0.0996 | 0.0961 | 0.1302 | 0.5606 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 57 | 200 | 0.2619 | 11.61 | 3.053 | 0.7574 | 23105.5 | 14100000 | 11000000000 | 10100000000000 | 0.4691 | 0.1844 | 0.0363 | 0.0081 | 0.0726 | 0.0208 | 0.0726 | 0.0728 | 0.1501 | 0.0786 | 0.1622 | 0.1110 | 0.1671 | 0.1260 | 0.1574 | 0.1191 | 0.1090 | 0.1445 | 0.0726 | 0.3191 | 0.0003 | 0.0012 | 0.0013 | 0.0030 | 0.0023 | 0.0044 | 0.0077 | 0.0094 | 0.0229 | 0.0195 | 0.0265 | 0.0301 | 0.0245 | 0.0248 | 0.0368 | 0.0387 | 0.8777 | 0.8689 | 0.0011 | 0.0000 | 0.0011 | 0.0004 | 0.0022 | 0.0024 | 0.0108 | 0.0091 | 0.0238 | 0.0234 | 0.0309 | 0.0313 | 0.0313 | 0.0317 | 0.0395 | 0.0527 | 0.8593 | 0.8490 | 0.0003 | 0.0007 | 0.0048 | 0.0104 | 0.0214 | 0.0308 | 0.0235 | 0.0443 | 0.8637 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1074 | 767 | | 4851 | 8558 | 206.5 | 55.00 | 108.27 | 109.37 | 139 | 160 | 174 | 187 | 202 | 217 | 232 | 251 | 282 | 0.1187 | 1016 | 0.484 | 105.59 | 20.81 | 4 | 0.0662 | 321 | 0.0008 | 57.36 | 7.309 | 0.1587 | 45680.7 | 10800000 | 2680000000 | 703000000000 | 0.4637 | 0.1868 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0086 | 0.0009 | 0.0413 | 0.0069 | 0.0994 | 0.0313 | 0.1640 | 0.0778 | 0.1659 | 0.0680 | 0.1872 | 0.1041 | 0.3321 | 0.7110 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0019 | 0.0006 | 0.0119 | 0.0039 | 0.0380 | 0.0199 | 0.0697 | 0.0448 | 0.0629 | 0.0307 | 0.0941 | 0.0474 | 0.7209 | 0.8527 | 0.0078 | 0.0123 | 0.0059 | 0.0123 | 0.0157 | 0.0567 | 0.0793 | 0.0961 | 0.1360 | 0.1995 | 0.1634 | 0.1847 | 0.1164 | 0.1059 | 0.1585 | 0.1256 | 0.3170 | 0.2069 | 0.0000 | 0.0013 | 0.0048 | 0.0255 | 0.0867 | 0.1175 | 0.1122 | 0.1373 | 0.5147 | 12 | 18 | 29 | 47 | 69 | 99 | 134 | 187 | 268 | 0.0244 | 13.32 | 5.257 | 0.4878 | 23683.4 | 7140000 | 2580000000 | 1050000000000 | 0.5580 | 0.1201 | 0.0405 | 0.0014 | 0.1364 | 0.0151 | 0.1957 | 0.0713 | 0.2286 | 0.1138 | 0.1722 | 0.1731 | 0.1091 | 0.2097 | 0.0640 | 0.1398 | 0.0301 | 0.1316 | 0.0235 | 0.1444 | 0.0008 | 0.0007 | 0.0029 | 0.0009 | 0.0080 | 0.0059 | 0.0252 | 0.0204 | 0.0707 | 0.0557 | 0.1162 | 0.1042 | 0.0849 | 0.0847 | 0.1154 | 0.1074 | 0.5760 | 0.6202 | 0.0007 | 0.0027 | 0.0045 | 0.0063 | 0.0142 | 0.0144 | 0.0359 | 0.0395 | 0.0864 | 0.0997 | 0.1253 | 0.1307 | 0.1029 | 0.1150 | 0.1377 | 0.1370 | 0.4923 | 0.4546 | 0.0019 | 0.0031 | 0.0084 | 0.0273 | 0.0769 | 0.1256 | 0.0924 | 0.1293 | 0.5352 |
| MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 771 | 431 | | 4723 | 9875 | 420.9 | 161.67 | 55.15 | 99.89 | 200 | 251 | 303 | 365 | 431 | 482 | 522 | 568 | 629 | 0.0788 | 778 | 0.731 | 105.48 | 21.21 | 6 | 0.0565 | 267 | 0.0006 | 80.85 | 7.710 | 0.1749 | 203288.0 | 108000000 | 61500000000 | 36800000000000 | 0.4984 | 0.1471 | 0.0007 | 0.0003 | 0.0007 | 0.0010 | 0.0216 | 0.0033 | 0.0404 | 0.0080 | 0.1246 | 0.0501 | 0.1865 | 0.0951 | 0.1461 | 0.0607 | 0.1538 | 0.0921 | 0.3257 | 0.6894 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0046 | 0.0034 | 0.0355 | 0.0308 | 0.0624 | 0.0490 | 0.0309 | 0.0300 | 0.0558 | 0.0477 | 0.8106 | 0.8391 | 0.0012 | 0.0000 | 0.0025 | 0.0000 | 0.0037 | 0.0000 | 0.0211 | 0.0000 | 0.0460 | 0.0000 | 0.0814 | 0.0000 | 0.0534 | 0.0000 | 0.0764 | 0.0000 | 0.7141 | 1.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0061 | 0.0442 | 0.0626 | 0.0421 | 0.0646 | 0.7799 | 10 | 11 | 12 | 13 | 15 | 20 | 30 | 66 | 151 | 0.2033 | 1.45 | 2.515 | 0.7047 | 13017.7 | 5530000 | 3000000000 | 1870000000000 | 0.6272 | 0.0766 | 0.0281 | 0.0028 | 0.0884 | 0.0139 | 0.1165 | 0.0558 | 0.1908 | 0.0883 | 0.2028 | 0.1403 | 0.1767 | 0.1589 | 0.1145 | 0.1608 | 0.0643 | 0.1673 | 0.0181 | 0.2119 | 0.0004 | 0.0007 | 0.0008 | 0.0010 | 0.0012 | 0.0042 | 0.0132 | 0.0178 | 0.0474 | 0.0437 | 0.0783 | 0.0615 | 0.0602 | 0.0612 | 0.0799 | 0.0829 | 0.7186 | 0.7269 | 0.0000 | 0.0000 | 0.0010 | 0.0011 | 0.0055 | 0.0056 | 0.0146 | 0.0202 | 0.0592 | 0.0633 | 0.0933 | 0.0959 | 0.0607 | 0.0774 | 0.0933 | 0.0970 | 0.6724 | 0.6396 | 0.0005 | 0.0000 | 0.0027 | 0.0140 | 0.0564 | 0.0794 | 0.0609 | 0.0947 | 0.6916 |
| MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 290 | 147 | | 6040 | 9656 | 458.9 | 90.94 | 116.43 | 141.69 | 320 | 377 | 416 | 448 | 476 | 496 | 516 | 535 | 564 | 0.0814 | 786 | 0.959 | 113.89 | 38.05 | 3 | 0.0513 | 310 | 0.0010 | 25.64 | 7.209 | 0.2429 | 218861.0 | 108000000 | 54400000000 | 28000000000000 | 0.4152 | 0.2180 | 0.0005 | 0.0000 | 0.0019 | 0.0003 | 0.0044 | 0.0003 | 0.0102 | 0.0015 | 0.0333 | 0.0148 | 0.0643 | 0.0297 | 0.0578 | 0.0191 | 0.0881 | 0.0275 | 0.7395 | 0.9067 | 0.0000 | 0.0000 | 0.0000 | 0.0003 | 0.0012 | 0.0002 | 0.0026 | 0.0009 | 0.0174 | 0.0138 | 0.0319 | 0.0281 | 0.0218 | 0.0148 | 0.0325 | 0.0215 | 0.8926 | 0.9203 | 0.0108 | 0.0476 | 0.0084 | 0.0476 | 0.0251 | 0.1190 | 0.0514 | 0.0952 | 0.0825 | 0.2381 | 0.1172 | 0.0952 | 0.0921 | 0.1905 | 0.1077 | 0.0952 | 0.5048 | 0.0714 | 0.0003 | 0.0018 | 0.0041 | 0.0097 | 0.0264 | 0.0364 | 0.0416 | 0.0630 | 0.8168 | 13 | 18 | 27 | 38 | 53 | 77 | 124 | 203 | 323 | 0.0304 | 16.12 | 5.130 | 0.4988 | 33628.8 | 14200000 | 7210000000 | 4150000000000 | 0.4981 | 0.1590 | 0.0724 | 0.0035 | 0.2453 | 0.0225 | 0.2909 | 0.1207 | 0.1890 | 0.1819 | 0.1206 | 0.2159 | 0.0456 | 0.1813 | 0.0214 | 0.1207 | 0.0107 | 0.0924 | 0.0040 | 0.0612 | 0.0006 | 0.0007 | 0.0032 | 0.0022 | 0.0044 | 0.0063 | 0.0247 | 0.0243 | 0.0831 | 0.0762 | 0.1064 | 0.0919 | 0.0657 | 0.0672 | 0.1041 | 0.1014 | 0.6078 | 0.6299 | 0.0011 | 0.0000 | 0.0045 | 0.0059 | 0.0074 | 0.0121 | 0.0364 | 0.0422 | 0.0961 | 0.0945 | 0.1088 | 0.1225 | 0.0831 | 0.0895 | 0.1184 | 0.1171 | 0.5442 | 0.5161 | 0.0013 | 0.0016 | 0.0069 | 0.0310 | 0.0844 | 0.1105 | 0.0719 | 0.1049 | 0.5874 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 271 | 847 | | 908 | 1431 | 91.8 | 33.70 | 687.44 | 391.20 | 43 | 63 | 77 | 87 | 93 | 101 | 107 | 116 | 134 | 0.2628 | 376 | 0.421 | 172.41 | 28.64 | 1 | 0.6244 | 567 | 0.0021 | 37.97 | 6.338 | 0.1970 | 9567.4 | 1090000 | 135000000 | 17800000000 | 0.3571 | 0.2522 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0114 | 0.0030 | 0.0571 | 0.0091 | 0.1393 | 0.0619 | 0.1963 | 0.0937 | 0.1667 | 0.0967 | 0.1758 | 0.1450 | 0.2534 | 0.5906 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0060 | 0.0064 | 0.0538 | 0.0412 | 0.0837 | 0.0528 | 0.0658 | 0.0528 | 0.1046 | 0.0670 | 0.6861 | 0.7796 | 0.0087 | 0.0175 | 0.0000 | 0.0000 | 0.0087 | 0.0263 | 0.0563 | 0.0614 | 0.1255 | 0.1228 | 0.1558 | 0.1228 | 0.1169 | 0.0877 | 0.1169 | 0.1667 | 0.4113 | 0.3947 | 0.0000 | 0.0000 | 0.0083 | 0.0188 | 0.0708 | 0.1188 | 0.0792 | 0.1125 | 0.5917 | 182 | 286 | 422 | 565 | 661 | 778 | 882 | 1021 | 1232 | 0.0013 | 104.63 | 6.818 | 0.1663 | 625506.0 | 665000000 | 783000000000 | 994000000000000 | 0.4941 | 0.1384 | 0.0138 | 0.0030 | 0.0801 | 0.0120 | 0.1713 | 0.0360 | 0.1685 | 0.0810 | 0.2293 | 0.1589 | 0.1547 | 0.1799 | 0.1105 | 0.1664 | 0.0497 | 0.1709 | 0.0221 | 0.1919 | 0.0000 | 0.0000 | 0.0023 | 0.0000 | 0.0148 | 0.0050 | 0.0319 | 0.0308 | 0.1105 | 0.0876 | 0.1390 | 0.1194 | 0.1378 | 0.1095 | 0.1412 | 0.1443 | 0.4226 | 0.5035 | 0.0019 | 0.0030 | 0.0233 | 0.0296 | 0.0233 | 0.0266 | 0.0698 | 0.1272 | 0.1550 | 0.1775 | 0.1609 | 0.2160 | 0.1453 | 0.1183 | 0.1221 | 0.1124 | 0.2985 | 0.1893 | 0.0000 | 0.0116 | 0.0217 | 0.0564 | 0.1302 | 0.1664 | 0.1230 | 0.1302 | 0.3603 |