High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 199 | 260 | 10686 | 24087 | 343.1 | 42.34 | 218.62 | 243.80 | 294 | 309 | 319 | 329 | 339 | 349 | 361 | 376 | 398 | 0.0560 | 1348 | 1.108 | 80.65 | 27.02 | 2 | 0.0188 | 201 | 0.0020 | 20.94 | 6.553 | 0.2495 | 119532.0 | 42300000 | 15200000000 | 5550000000000 | 0.4430 | 0.2105 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0032 | 0.0005 | 0.0194 | 0.0089 | 0.0355 | 0.0176 | 0.0461 | 0.0113 | 0.0755 | 0.0211 | 0.8188 | 0.9407 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0015 | 0.0000 | 0.0114 | 0.0086 | 0.0212 | 0.0159 | 0.0232 | 0.0077 | 0.0352 | 0.0146 | 0.9074 | 0.9532 | 0.0199 | 0.0000 | 0.0385 | 0.0000 | 0.0442 | 0.0000 | 0.0855 | 0.0000 | 0.0954 | 0.0000 | 0.1311 | 0.0000 | 0.1197 | 0.0000 | 0.1211 | 0.0000 | 0.3447 | 0.0000 | 0.0047 | 0.0098 | 0.0155 | 0.0422 | 0.0674 | 0.0986 | 0.1131 | 0.1277 | 0.5211 | 18 | 23 | 29 | 46 | 110 | 198 | 297 | 422 | 589 | 0.0307 | 46.12 | 5.951 | 0.4302 | 107227.0 | 68300000 | 50200000000 | 40800000000000 | 0.5298 | 0.1259 | 0.0245 | 0.0018 | 0.1127 | 0.0149 | 0.2277 | 0.0610 | 0.1750 | 0.0972 | 0.1550 | 0.1809 | 0.1245 | 0.2068 | 0.0732 | 0.1277 | 0.0609 | 0.1204 | 0.0464 | 0.1894 | 0.0000 | 0.0000 | 0.0005 | 0.0002 | 0.0017 | 0.0016 | 0.0077 | 0.0073 | 0.0415 | 0.0338 | 0.0707 | 0.0588 | 0.0495 | 0.0417 | 0.0772 | 0.0625 | 0.7513 | 0.7941 | 0.0004 | 0.0004 | 0.0010 | 0.0016 | 0.0029 | 0.0041 | 0.0139 | 0.0205 | 0.0578 | 0.0653 | 0.0903 | 0.1105 | 0.0763 | 0.0890 | 0.1087 | 0.1110 | 0.6487 | 0.5975 | 0.0001 | 0.0011 | 0.0034 | 0.0105 | 0.0471 | 0.0826 | 0.0615 | 0.0887 | 0.7050 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 402 | 281 | 5163 | 11094 | 132.9 | 31.75 | 204.40 | 192.72 | 98 | 107 | 114 | 120 | 127 | 135 | 144 | 156 | 174 | 0.0753 | 835 | 1.001 | 90.14 | 24.74 | 1 | 0.0424 | 219 | 0.0024 | 20.29 | 6.351 | 0.2592 | 18683.1 | 2790000 | 443000000 | 75300000000 | 0.4578 | 0.1909 | 0.0003 | 0.0000 | 0.0025 | 0.0000 | 0.0034 | 0.0002 | 0.0224 | 0.0012 | 0.0771 | 0.0208 | 0.1572 | 0.0445 | 0.1683 | 0.0420 | 0.1981 | 0.0794 | 0.3707 | 0.8120 | 0.0002 | 0.0000 | 0.0019 | 0.0000 | 0.0019 | 0.0000 | 0.0091 | 0.0000 | 0.0343 | 0.0121 | 0.0698 | 0.0263 | 0.0770 | 0.0152 | 0.1062 | 0.0349 | 0.6996 | 0.9115 | 0.0044 | 0.0126 | 0.0142 | 0.0158 | 0.0230 | 0.0536 | 0.0678 | 0.1073 | 0.1497 | 0.1956 | 0.1913 | 0.1546 | 0.1049 | 0.1577 | 0.1355 | 0.1325 | 0.3093 | 0.1703 | 0.0031 | 0.0040 | 0.0108 | 0.0333 | 0.0787 | 0.1393 | 0.1016 | 0.1326 | 0.4966 | 20 | 34 | 61 | 100 | 147 | 198 | 262 | 353 | 492 | 0.0054 | 71.93 | 6.900 | 0.2998 | 78916.5 | 40300000 | 24100000000 | 16000000000000 | 0.4531 | 0.1995 | 0.0210 | 0.0003 | 0.1004 | 0.0108 | 0.2033 | 0.0378 | 0.1881 | 0.0917 | 0.1512 | 0.1677 | 0.1595 | 0.2108 | 0.0921 | 0.1540 | 0.0508 | 0.1423 | 0.0337 | 0.1847 | 0.0004 | 0.0002 | 0.0012 | 0.0020 | 0.0031 | 0.0030 | 0.0172 | 0.0109 | 0.0545 | 0.0442 | 0.0980 | 0.0771 | 0.0764 | 0.0584 | 0.1021 | 0.0867 | 0.6471 | 0.7176 | 0.0011 | 0.0020 | 0.0011 | 0.0023 | 0.0078 | 0.0106 | 0.0300 | 0.0381 | 0.0728 | 0.0866 | 0.1296 | 0.1333 | 0.0923 | 0.0899 | 0.1143 | 0.1148 | 0.5510 | 0.5224 | 0.0007 | 0.0014 | 0.0067 | 0.0219 | 0.0631 | 0.1112 | 0.0841 | 0.1170 | 0.5940 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1211 | 757 | 6987 | 17413 | 330.1 | 42.49 | 131.75 | 174.14 | 277 | 295 | 309 | 320 | 331 | 341 | 352 | 366 | 384 | 0.0637 | 1110 | 0.875 | 72.84 | 16.16 | 1 | 0.0238 | 166 | 0.0022 | 16.55 | 6.447 | 0.2611 | 110777.0 | 37800000 | 13100000000 | 4580000000000 | 0.4400 | 0.2087 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0010 | 0.0000 | 0.0062 | 0.0000 | 0.0213 | 0.0109 | 0.0321 | 0.0178 | 0.0485 | 0.0100 | 0.0745 | 0.0186 | 0.8160 | 0.9427 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0000 | 0.0128 | 0.0109 | 0.0169 | 0.0178 | 0.0198 | 0.0095 | 0.0305 | 0.0166 | 0.9167 | 0.9453 | 0.0122 | 0.0000 | 0.0389 | 1.0000 | 0.0681 | 0.0000 | 0.1387 | 0.0000 | 0.1363 | 0.0000 | 0.1533 | 0.0000 | 0.1314 | 0.0000 | 0.1265 | 0.0000 | 0.1946 | 0.0000 | 0.0017 | 0.0047 | 0.0111 | 0.0255 | 0.0505 | 0.0813 | 0.0921 | 0.1160 | 0.6171 | 11 | 14 | 16 | 20 | 45 | 85 | 148 | 242 | 391 | 0.0761 | 18.56 | 4.883 | 0.5466 | 47679.7 | 24000000 | 14300000000 | 9510000000000 | 0.5710 | 0.1004 | 0.0354 | 0.0022 | 0.1286 | 0.0170 | 0.1973 | 0.0815 | 0.1517 | 0.1130 | 0.1402 | 0.1735 | 0.1156 | 0.1590 | 0.0860 | 0.1101 | 0.0744 | 0.1093 | 0.0708 | 0.2342 | 0.0002 | 0.0003 | 0.0005 | 0.0013 | 0.0017 | 0.0015 | 0.0103 | 0.0083 | 0.0444 | 0.0392 | 0.0713 | 0.0616 | 0.0547 | 0.0447 | 0.0799 | 0.0686 | 0.7370 | 0.7746 | 0.0002 | 0.0007 | 0.0022 | 0.0016 | 0.0044 | 0.0034 | 0.0156 | 0.0158 | 0.0577 | 0.0657 | 0.0944 | 0.1062 | 0.0716 | 0.0725 | 0.0954 | 0.1069 | 0.6586 | 0.6274 | 0.0004 | 0.0009 | 0.0034 | 0.0130 | 0.0497 | 0.0852 | 0.0639 | 0.0887 | 0.6949 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 705 | 883 | 6676 | 9244 | 499.2 | 67.15 | 152.67 | 174.40 | 413 | 445 | 465 | 483 | 499 | 516 | 533 | 554 | 585 | 0.0900 | 832 | 1.232 | 101.42 | 42.43 | 1 | 0.0400 | 267 | 0.0009 | 54.50 | 7.284 | 0.1641 | 253716.0 | 131000000 | 68900000000 | 36800000000000 | 0.4286 | 0.2213 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0014 | 0.0000 | 0.0060 | 0.0000 | 0.0214 | 0.0109 | 0.0488 | 0.0210 | 0.0590 | 0.0100 | 0.0846 | 0.0168 | 0.7780 | 0.9412 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0027 | 0.0000 | 0.0136 | 0.0106 | 0.0283 | 0.0205 | 0.0247 | 0.0094 | 0.0369 | 0.0151 | 0.8931 | 0.9443 | 0.0165 | 0.0000 | 0.0412 | 0.0000 | 0.0576 | 0.0000 | 0.0864 | 0.0000 | 0.1358 | 0.0000 | 0.1296 | 0.0000 | 0.1276 | 0.0000 | 0.1379 | 0.0000 | 0.2675 | 0.0000 | 0.0018 | 0.0036 | 0.0083 | 0.0283 | 0.0676 | 0.1221 | 0.1140 | 0.1355 | 0.5189 | 19 | 26 | 37 | 53 | 74 | 110 | 169 | 273 | 415 | 0.0207 | 24.07 | 5.517 | 0.4810 | 53719.9 | 26700000 | 15900000000 | 10600000000000 | 0.4686 | 0.1593 | 0.0797 | 0.0005 | 0.2210 | 0.0235 | 0.2295 | 0.1208 | 0.1292 | 0.1504 | 0.1075 | 0.1711 | 0.0821 | 0.1602 | 0.0483 | 0.1022 | 0.0628 | 0.1203 | 0.0399 | 0.1509 | 0.0003 | 0.0002 | 0.0015 | 0.0005 | 0.0038 | 0.0027 | 0.0145 | 0.0131 | 0.0737 | 0.0515 | 0.1088 | 0.1038 | 0.0748 | 0.0620 | 0.1129 | 0.1048 | 0.6098 | 0.6614 | 0.0000 | 0.0000 | 0.0008 | 0.0035 | 0.0050 | 0.0039 | 0.0218 | 0.0226 | 0.0916 | 0.0960 | 0.1439 | 0.1633 | 0.0871 | 0.0886 | 0.1226 | 0.1363 | 0.5273 | 0.4859 | 0.0003 | 0.0003 | 0.0037 | 0.0141 | 0.0844 | 0.1335 | 0.0820 | 0.1187 | 0.5629 | |
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 686 | 625 | 6653 | 21616 | 335.3 | 63.66 | 169.19 | 212.41 | 264 | 281 | 295 | 309 | 325 | 342 | 362 | 385 | 425 | 0.0403 | 871 | 1.098 | 108.24 | 36.69 | 1 | 0.0412 | 274 | 0.0007 | 66.56 | 7.535 | 0.1518 | 116505.0 | 42000000 | 15700000000 | 6090000000000 | 0.4550 | 0.1972 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0023 | 0.0002 | 0.0068 | 0.0011 | 0.0474 | 0.0135 | 0.1064 | 0.0297 | 0.1104 | 0.0278 | 0.1437 | 0.0363 | 0.5825 | 0.8914 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0029 | 0.0000 | 0.0239 | 0.0090 | 0.0529 | 0.0155 | 0.0543 | 0.0084 | 0.0731 | 0.0141 | 0.7917 | 0.9529 | 0.0030 | 0.0000 | 0.0120 | 0.0243 | 0.0200 | 0.0208 | 0.0430 | 0.1250 | 0.1289 | 0.1736 | 0.1548 | 0.2153 | 0.1009 | 0.1215 | 0.1419 | 0.1458 | 0.3956 | 0.1736 | 0.0017 | 0.0010 | 0.0113 | 0.0284 | 0.0825 | 0.1140 | 0.1062 | 0.1308 | 0.5240 | 11 | 13 | 15 | 21 | 59 | 135 | 223 | 332 | 480 | 0.0461 | 55.65 | 5.697 | 0.4308 | 73741.6 | 43100000 | 29900000000 | 23400000000000 | 0.4089 | 0.2338 | 0.0463 | 0.0015 | 0.1935 | 0.0167 | 0.2745 | 0.1152 | 0.1777 | 0.1388 | 0.1357 | 0.1962 | 0.0901 | 0.1912 | 0.0542 | 0.1307 | 0.0213 | 0.1096 | 0.0067 | 0.1001 | 0.0001 | 0.0001 | 0.0014 | 0.0005 | 0.0035 | 0.0017 | 0.0088 | 0.0064 | 0.0446 | 0.0382 | 0.0850 | 0.0684 | 0.0604 | 0.0514 | 0.0846 | 0.0704 | 0.7116 | 0.7629 | 0.0009 | 0.0006 | 0.0029 | 0.0029 | 0.0063 | 0.0060 | 0.0129 | 0.0147 | 0.0599 | 0.0658 | 0.1035 | 0.1203 | 0.0786 | 0.0886 | 0.1056 | 0.1095 | 0.6295 | 0.5914 | 0.0001 | 0.0022 | 0.0036 | 0.0127 | 0.0496 | 0.0976 | 0.0729 | 0.0936 | 0.6678 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1078 | 76 | 3929 | 6047 | 161.4 | 44.19 | 132.87 | 179.68 | 115 | 126 | 135 | 144 | 153 | 164 | 177 | 192 | 220 | 0.1057 | 639 | 1.011 | 168.43 | 62.07 | 1 | 0.1168 | 459 | 0.0015 | 39.33 | 6.819 | 0.1959 | 28002.9 | 5250000 | 1070000000 | 240000000000 | 0.4412 | 0.2076 | 0.0013 | 0.0000 | 0.0035 | 0.0003 | 0.0083 | 0.0017 | 0.0372 | 0.0034 | 0.0959 | 0.0278 | 0.1713 | 0.0613 | 0.1827 | 0.0573 | 0.1866 | 0.0994 | 0.3132 | 0.7487 | 0.0010 | 0.0000 | 0.0007 | 0.0003 | 0.0023 | 0.0003 | 0.0128 | 0.0000 | 0.0437 | 0.0177 | 0.0801 | 0.0303 | 0.0782 | 0.0230 | 0.1120 | 0.0483 | 0.6693 | 0.8803 | 0.0066 | 0.0058 | 0.0092 | 0.0203 | 0.0328 | 0.0407 | 0.0814 | 0.0872 | 0.1273 | 0.1802 | 0.1654 | 0.2122 | 0.1247 | 0.1105 | 0.1535 | 0.1337 | 0.2992 | 0.2093 | 0.0035 | 0.0035 | 0.0106 | 0.0388 | 0.1052 | 0.1240 | 0.1217 | 0.1499 | 0.4427 | 9 | 12 | 16 | 25 | 49 | 95 | 150 | 233 | 366 | 0.0201 | 68.11 | 5.908 | 0.3842 | 49932.6 | 27200000 | 17800000000 | 13000000000000 | 0.5438 | 0.1149 | 0.0657 | 0.0029 | 0.2044 | 0.0115 | 0.2117 | 0.1319 | 0.1387 | 0.1616 | 0.1515 | 0.2122 | 0.0985 | 0.1539 | 0.0511 | 0.1023 | 0.0547 | 0.0918 | 0.0237 | 0.1319 | 0.0004 | 0.0000 | 0.0018 | 0.0004 | 0.0009 | 0.0031 | 0.0234 | 0.0147 | 0.0661 | 0.0570 | 0.0974 | 0.0892 | 0.0793 | 0.0694 | 0.1058 | 0.0927 | 0.6249 | 0.6735 | 0.0017 | 0.0007 | 0.0006 | 0.0000 | 0.0076 | 0.0046 | 0.0285 | 0.0359 | 0.0802 | 0.0894 | 0.1197 | 0.1305 | 0.0953 | 0.0868 | 0.1104 | 0.1194 | 0.5561 | 0.5329 | 0.0010 | 0.0030 | 0.0081 | 0.0186 | 0.0756 | 0.1149 | 0.0832 | 0.1144 | 0.5811 | |||
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 634 | 836 | 6694 | 23123 | 220.1 | 45.92 | 161.99 | 175.74 | 165 | 181 | 193 | 204 | 215 | 227 | 240 | 256 | 280 | 0.0480 | 1111 | 1.210 | 102.65 | 44.29 | 1 | 0.0420 | 281 | 0.0011 | 40.91 | 7.097 | 0.1838 | 50535.0 | 12100000 | 3040000000 | 797000000000 | 0.4401 | 0.2135 | 0.0002 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0002 | 0.0159 | 0.0003 | 0.0615 | 0.0172 | 0.1197 | 0.0311 | 0.1488 | 0.0369 | 0.1834 | 0.0515 | 0.4669 | 0.8628 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0062 | 0.0000 | 0.0277 | 0.0126 | 0.0551 | 0.0171 | 0.0627 | 0.0163 | 0.0885 | 0.0249 | 0.7582 | 0.9291 | 0.0046 | 0.0108 | 0.0147 | 0.0179 | 0.0394 | 0.0502 | 0.0879 | 0.1613 | 0.1319 | 0.1613 | 0.1712 | 0.1864 | 0.1071 | 0.1111 | 0.1328 | 0.0932 | 0.3104 | 0.2079 | 0.0013 | 0.0016 | 0.0090 | 0.0303 | 0.0940 | 0.1211 | 0.1137 | 0.1523 | 0.4767 | 11 | 13 | 18 | 38 | 92 | 162 | 235 | 308 | 417 | 0.0450 | 24.09 | 5.615 | 0.4490 | 57122.6 | 25900000 | 13700000000 | 8060000000000 | 0.4415 | 0.1960 | 0.0450 | 0.0017 | 0.1921 | 0.0096 | 0.3192 | 0.0939 | 0.1711 | 0.1707 | 0.1124 | 0.2071 | 0.0816 | 0.1996 | 0.0401 | 0.1194 | 0.0308 | 0.1084 | 0.0078 | 0.0896 | 0.0005 | 0.0001 | 0.0009 | 0.0005 | 0.0008 | 0.0016 | 0.0092 | 0.0074 | 0.0453 | 0.0386 | 0.0833 | 0.0715 | 0.0621 | 0.0516 | 0.0918 | 0.0767 | 0.7061 | 0.7520 | 0.0001 | 0.0007 | 0.0010 | 0.0017 | 0.0034 | 0.0074 | 0.0198 | 0.0214 | 0.0603 | 0.0717 | 0.1056 | 0.1113 | 0.0810 | 0.0864 | 0.1068 | 0.1131 | 0.6220 | 0.5862 | 0.0001 | 0.0006 | 0.0018 | 0.0130 | 0.0555 | 0.0911 | 0.0731 | 0.1019 | 0.6628 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 422 | 387 | 8367 | 21686 | 338.6 | 51.23 | 216.62 | 253.93 | 275 | 292 | 307 | 321 | 337 | 351 | 367 | 383 | 406 | 0.0592 | 1284 | 1.224 | 118.07 | 44.69 | 1 | 0.0354 | 296 | 0.0016 | 21.25 | 6.715 | 0.2518 | 117279.0 | 41500000 | 15000000000 | 5540000000000 | 0.4429 | 0.2078 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0080 | 0.0001 | 0.0305 | 0.0112 | 0.0543 | 0.0192 | 0.0664 | 0.0146 | 0.1150 | 0.0208 | 0.7238 | 0.9341 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0005 | 0.0000 | 0.0034 | 0.0000 | 0.0155 | 0.0105 | 0.0264 | 0.0169 | 0.0305 | 0.0096 | 0.0535 | 0.0147 | 0.8698 | 0.9484 | 0.0147 | 0.0000 | 0.0209 | 0.0000 | 0.0466 | 0.0000 | 0.0798 | 0.0000 | 0.1325 | 0.0000 | 0.1509 | 0.0000 | 0.1166 | 0.0000 | 0.1387 | 0.0000 | 0.2994 | 0.0000 | 0.0029 | 0.0037 | 0.0079 | 0.0179 | 0.0489 | 0.0872 | 0.0769 | 0.1138 | 0.6407 | 23 | 31 | 44 | 65 | 97 | 158 | 256 | 389 | 599 | 0.0168 | 30.30 | 6.006 | 0.4494 | 111401.0 | 80200000 | 68700000000 | 66100000000000 | 0.5043 | 0.1472 | 0.0237 | 0.0026 | 0.1369 | 0.0072 | 0.2565 | 0.0574 | 0.1751 | 0.1186 | 0.1568 | 0.1945 | 0.1196 | 0.2092 | 0.0501 | 0.1261 | 0.0356 | 0.1132 | 0.0458 | 0.1711 | 0.0002 | 0.0003 | 0.0005 | 0.0006 | 0.0022 | 0.0014 | 0.0105 | 0.0091 | 0.0514 | 0.0447 | 0.0911 | 0.0790 | 0.0565 | 0.0498 | 0.0825 | 0.0754 | 0.7050 | 0.7396 | 0.0003 | 0.0002 | 0.0011 | 0.0016 | 0.0023 | 0.0053 | 0.0156 | 0.0192 | 0.0627 | 0.0685 | 0.1061 | 0.1174 | 0.0749 | 0.0819 | 0.0955 | 0.0997 | 0.6414 | 0.6062 | 0.0001 | 0.0003 | 0.0026 | 0.0142 | 0.0598 | 0.0932 | 0.0668 | 0.0874 | 0.6756 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1060 | 312 | 8531 | 15239 | 406.2 | 51.13 | 226.15 | 245.25 | 342 | 364 | 380 | 392 | 404 | 416 | 431 | 449 | 474 | 0.0668 | 1018 | 0.868 | 57.87 | 17.89 | 1 | 0.0178 | 152 | 0.0013 | 38.37 | 6.954 | 0.1978 | 167626.0 | 70200000 | 29900000000 | 12900000000000 | 0.4561 | 0.1965 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0013 | 0.0000 | 0.0042 | 0.0000 | 0.0191 | 0.0097 | 0.0469 | 0.0162 | 0.0566 | 0.0088 | 0.0892 | 0.0171 | 0.7825 | 0.9482 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0011 | 0.0000 | 0.0126 | 0.0097 | 0.0255 | 0.0162 | 0.0268 | 0.0088 | 0.0439 | 0.0152 | 0.8900 | 0.9501 | 0.0146 | 1.0000 | 0.0419 | 0.0000 | 0.0419 | 0.0000 | 0.1129 | 0.0000 | 0.1548 | 0.0000 | 0.1876 | 0.0000 | 0.1220 | 0.0000 | 0.1275 | 0.0000 | 0.1967 | 0.0000 | 0.0026 | 0.0043 | 0.0115 | 0.0412 | 0.0740 | 0.1178 | 0.1135 | 0.1283 | 0.5068 | 15 | 19 | 31 | 68 | 137 | 220 | 311 | 421 | 569 | 0.0214 | 62.72 | 6.209 | 0.3748 | 111286.0 | 74000000 | 60400000000 | 58100000000000 | 0.5099 | 0.1391 | 0.0526 | 0.0022 | 0.1940 | 0.0114 | 0.2544 | 0.1134 | 0.1674 | 0.1438 | 0.1298 | 0.1878 | 0.1032 | 0.1837 | 0.0545 | 0.1188 | 0.0292 | 0.1096 | 0.0149 | 0.1292 | 0.0000 | 0.0001 | 0.0001 | 0.0004 | 0.0007 | 0.0003 | 0.0079 | 0.0047 | 0.0500 | 0.0399 | 0.0844 | 0.0694 | 0.0697 | 0.0522 | 0.1028 | 0.0844 | 0.6841 | 0.7486 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0027 | 0.0049 | 0.0148 | 0.0281 | 0.0769 | 0.0926 | 0.1317 | 0.1530 | 0.1039 | 0.1070 | 0.1377 | 0.1459 | 0.5322 | 0.4672 | 0.0000 | 0.0000 | 0.0020 | 0.0090 | 0.0602 | 0.1073 | 0.0860 | 0.1254 | 0.6102 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 857 | 519 | 7896 | 25086 | 549.1 | 111.64 | 115.29 | 108.29 | 407 | 452 | 487 | 515 | 543 | 571 | 603 | 640 | 694 | 0.0453 | 1137 | 0.998 | 121.50 | 33.97 | 1 | 0.0384 | 303 | 0.0006 | 71.62 | 7.693 | 0.1462 | 313964.0 | 187000000 | 115000000000 | 73300000000000 | 0.4442 | 0.2062 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0019 | 0.0000 | 0.0110 | 0.0013 | 0.0526 | 0.0162 | 0.1198 | 0.0335 | 0.1264 | 0.0258 | 0.1582 | 0.0429 | 0.5295 | 0.8802 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0040 | 0.0000 | 0.0247 | 0.0109 | 0.0576 | 0.0223 | 0.0544 | 0.0138 | 0.0738 | 0.0246 | 0.7850 | 0.9284 | 0.0055 | 0.0067 | 0.0079 | 0.0134 | 0.0259 | 0.0235 | 0.0715 | 0.0705 | 0.1155 | 0.1779 | 0.1595 | 0.2315 | 0.1147 | 0.1409 | 0.1304 | 0.1342 | 0.3692 | 0.2013 | 0.0003 | 0.0021 | 0.0045 | 0.0279 | 0.0760 | 0.1244 | 0.0942 | 0.1323 | 0.5384 | 14 | 19 | 30 | 51 | 80 | 116 | 158 | 205 | 271 | 0.0163 | 18.42 | 5.849 | 0.4162 | 25016.0 | 7180000 | 2480000000 | 993000000000 | 0.4965 | 0.1507 | 0.0497 | 0.0008 | 0.2062 | 0.0128 | 0.2854 | 0.1255 | 0.1474 | 0.1729 | 0.1169 | 0.1868 | 0.0873 | 0.1793 | 0.0490 | 0.1096 | 0.0336 | 0.0972 | 0.0245 | 0.1151 | 0.0003 | 0.0000 | 0.0008 | 0.0004 | 0.0022 | 0.0018 | 0.0130 | 0.0103 | 0.0633 | 0.0528 | 0.1135 | 0.0937 | 0.0729 | 0.0627 | 0.1138 | 0.0990 | 0.6201 | 0.6793 | 0.0006 | 0.0004 | 0.0013 | 0.0031 | 0.0045 | 0.0078 | 0.0266 | 0.0355 | 0.0880 | 0.1026 | 0.1507 | 0.1609 | 0.0929 | 0.1075 | 0.1339 | 0.1393 | 0.5016 | 0.4429 | 0.0004 | 0.0013 | 0.0028 | 0.0194 | 0.0737 | 0.1338 | 0.0833 | 0.1256 | 0.5598 | |||
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 717 | 772 | 5044 | 13779 | 301.7 | 59.20 | 210.76 | 220.75 | 231 | 249 | 265 | 280 | 295 | 312 | 331 | 354 | 385 | 0.0589 | 812 | 0.776 | 118.60 | 32.65 | 1 | 0.0632 | 319 | 0.0007 | 72.96 | 7.469 | 0.1451 | 94502.0 | 30700000 | 10300000000 | 3580000000000 | 0.4636 | 0.1931 | 0.0000 | 0.0000 | 0.0009 | 0.0000 | 0.0049 | 0.0000 | 0.0145 | 0.0006 | 0.0751 | 0.0121 | 0.1252 | 0.0311 | 0.1304 | 0.0313 | 0.1693 | 0.0459 | 0.4797 | 0.8791 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0044 | 0.0000 | 0.0323 | 0.0096 | 0.0650 | 0.0212 | 0.0617 | 0.0156 | 0.0939 | 0.0258 | 0.7425 | 0.9278 | 0.0060 | 0.0074 | 0.0072 | 0.0148 | 0.0241 | 0.0889 | 0.0869 | 0.1778 | 0.1351 | 0.1926 | 0.1966 | 0.2296 | 0.1230 | 0.1037 | 0.1460 | 0.1185 | 0.2750 | 0.0667 | 0.0004 | 0.0009 | 0.0051 | 0.0381 | 0.0908 | 0.1422 | 0.0934 | 0.1285 | 0.5004 | 12 | 16 | 29 | 71 | 138 | 216 | 302 | 388 | 517 | 0.0184 | 66.02 | 6.381 | 0.3575 | 93147.7 | 54300000 | 38200000000 | 31100000000000 | 0.5593 | 0.0982 | 0.0360 | 0.0028 | 0.1517 | 0.0183 | 0.2992 | 0.0785 | 0.1891 | 0.1391 | 0.1447 | 0.1813 | 0.0976 | 0.2120 | 0.0429 | 0.1411 | 0.0277 | 0.1141 | 0.0111 | 0.1128 | 0.0005 | 0.0000 | 0.0006 | 0.0013 | 0.0024 | 0.0029 | 0.0090 | 0.0067 | 0.0485 | 0.0391 | 0.0883 | 0.0705 | 0.0680 | 0.0561 | 0.1104 | 0.0882 | 0.6724 | 0.7352 | 0.0002 | 0.0007 | 0.0010 | 0.0007 | 0.0043 | 0.0064 | 0.0151 | 0.0203 | 0.0661 | 0.0835 | 0.1350 | 0.1546 | 0.0965 | 0.1018 | 0.1321 | 0.1450 | 0.5497 | 0.4870 | 0.0002 | 0.0009 | 0.0032 | 0.0112 | 0.0580 | 0.1055 | 0.0852 | 0.1259 | 0.6100 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 158 | 814 | 6792 | 9233 | 438.4 | 87.62 | 129.25 | 126.89 | 328 | 360 | 387 | 410 | 432 | 453 | 478 | 510 | 563 | 0.1039 | 959 | 1.120 | 105.12 | 29.02 | 1 | 0.0346 | 235 | 0.0009 | 45.63 | 7.284 | 0.1766 | 199847.0 | 94600000 | 46500000000 | 23600000000000 | 0.4114 | 0.2340 | 0.0002 | 0.0000 | 0.0009 | 0.0002 | 0.0029 | 0.0003 | 0.0152 | 0.0014 | 0.0530 | 0.0166 | 0.1082 | 0.0302 | 0.1148 | 0.0269 | 0.1594 | 0.0440 | 0.5454 | 0.8804 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0064 | 0.0000 | 0.0246 | 0.0109 | 0.0515 | 0.0199 | 0.0494 | 0.0108 | 0.0729 | 0.0223 | 0.7933 | 0.9361 | 0.0091 | 0.0087 | 0.0172 | 0.0435 | 0.0199 | 0.0913 | 0.0661 | 0.1174 | 0.1024 | 0.2261 | 0.1386 | 0.1174 | 0.1232 | 0.1739 | 0.1132 | 0.0870 | 0.4103 | 0.1348 | 0.0006 | 0.0025 | 0.0094 | 0.0253 | 0.0738 | 0.1200 | 0.1088 | 0.1385 | 0.5211 | 15 | 21 | 36 | 60 | 91 | 123 | 163 | 221 | 310 | 0.0144 | 22.41 | 5.893 | 0.4120 | 32805.8 | 11500000 | 4920000000 | 2420000000000 | 0.5918 | 0.1102 | 0.0326 | 0.0008 | 0.0932 | 0.0126 | 0.1546 | 0.0502 | 0.1430 | 0.0942 | 0.1492 | 0.1468 | 0.1430 | 0.1554 | 0.1072 | 0.1181 | 0.1049 | 0.1370 | 0.0723 | 0.2849 | 0.0002 | 0.0000 | 0.0012 | 0.0004 | 0.0062 | 0.0042 | 0.0208 | 0.0156 | 0.0649 | 0.0540 | 0.0900 | 0.0828 | 0.0815 | 0.0608 | 0.1083 | 0.0905 | 0.6269 | 0.6917 | 0.0017 | 0.0008 | 0.0031 | 0.0078 | 0.0133 | 0.0090 | 0.0269 | 0.0377 | 0.0941 | 0.1099 | 0.1339 | 0.1333 | 0.0896 | 0.1005 | 0.1210 | 0.1255 | 0.5164 | 0.4754 | 0.0009 | 0.0028 | 0.0079 | 0.0247 | 0.0791 | 0.1123 | 0.0879 | 0.1140 | 0.5705 | |||
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1177 | 177 | 8873 | 27955 | 248.5 | 47.11 | 109.86 | 157.87 | 191 | 208 | 221 | 233 | 244 | 256 | 271 | 287 | 314 | 0.0469 | 1311 | 0.994 | 127.91 | 39.00 | 1 | 0.0355 | 315 | 0.0008 | 53.04 | 7.325 | 0.1590 | 63995.2 | 17100000 | 4700000000 | 1340000000000 | 0.4343 | 0.2173 | 0.0002 | 0.0000 | 0.0002 | 0.0000 | 0.0027 | 0.0000 | 0.0120 | 0.0007 | 0.0522 | 0.0127 | 0.1214 | 0.0295 | 0.1345 | 0.0288 | 0.1777 | 0.0558 | 0.4991 | 0.8725 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0000 | 0.0244 | 0.0092 | 0.0562 | 0.0202 | 0.0603 | 0.0122 | 0.0912 | 0.0247 | 0.7617 | 0.9337 | 0.0052 | 0.0297 | 0.0140 | 0.0890 | 0.0295 | 0.0932 | 0.0820 | 0.1525 | 0.1462 | 0.2288 | 0.1640 | 0.1610 | 0.1248 | 0.0847 | 0.1388 | 0.0890 | 0.2954 | 0.0720 | 0.0024 | 0.0034 | 0.0098 | 0.0396 | 0.0875 | 0.1325 | 0.1151 | 0.1374 | 0.4723 | 8 | 10 | 12 | 14 | 18 | 43 | 118 | 226 | 348 | 0.1117 | 21.16 | 4.563 | 0.5542 | 36992.6 | 17000000 | 9310000000 | 5870000000000 | 0.4998 | 0.1706 | 0.1052 | 0.0037 | 0.2954 | 0.0329 | 0.2884 | 0.1793 | 0.1348 | 0.2009 | 0.0748 | 0.2214 | 0.0639 | 0.1482 | 0.0257 | 0.0933 | 0.0094 | 0.0743 | 0.0023 | 0.0461 | 0.0004 | 0.0000 | 0.0004 | 0.0006 | 0.0015 | 0.0012 | 0.0091 | 0.0073 | 0.0471 | 0.0423 | 0.0840 | 0.0719 | 0.0564 | 0.0505 | 0.0810 | 0.0788 | 0.7201 | 0.7475 | 0.0006 | 0.0005 | 0.0005 | 0.0015 | 0.0017 | 0.0041 | 0.0127 | 0.0145 | 0.0561 | 0.0526 | 0.0904 | 0.1071 | 0.0670 | 0.0757 | 0.1010 | 0.1065 | 0.6698 | 0.6375 | 0.0003 | 0.0003 | 0.0020 | 0.0116 | 0.0481 | 0.0925 | 0.0604 | 0.0911 | 0.6936 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 329 | 607 | 5771 | 20630 | 529.1 | 107.50 | 83.24 | 139.38 | 401 | 436 | 465 | 492 | 519 | 544 | 572 | 613 | 676 | 0.0490 | 1011 | 1.201 | 99.91 | 40.71 | 1 | 0.0452 | 261 | 0.0007 | 73.75 | 7.558 | 0.1339 | 291461.0 | 167000000 | 99900000000 | 62100000000000 | 0.4158 | 0.2294 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0031 | 0.0002 | 0.0148 | 0.0011 | 0.0604 | 0.0173 | 0.1177 | 0.0353 | 0.1405 | 0.0308 | 0.1599 | 0.0466 | 0.5026 | 0.8687 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0012 | 0.0000 | 0.0062 | 0.0000 | 0.0291 | 0.0118 | 0.0586 | 0.0242 | 0.0637 | 0.0139 | 0.0850 | 0.0235 | 0.7556 | 0.9266 | 0.0032 | 0.0079 | 0.0149 | 0.0277 | 0.0223 | 0.0316 | 0.0617 | 0.1067 | 0.1415 | 0.1225 | 0.1553 | 0.1858 | 0.0904 | 0.1225 | 0.1170 | 0.1304 | 0.3936 | 0.2648 | 0.0011 | 0.0023 | 0.0076 | 0.0345 | 0.0913 | 0.1330 | 0.1080 | 0.1258 | 0.4966 | 8 | 10 | 11 | 13 | 15 | 21 | 52 | 137 | 282 | 0.0906 | 17.39 | 4.254 | 0.5950 | 26353.8 | 12200000 | 6910000000 | 4480000000000 | 0.6077 | 0.0930 | 0.1055 | 0.0041 | 0.2829 | 0.0287 | 0.3598 | 0.1851 | 0.1526 | 0.2168 | 0.0596 | 0.2162 | 0.0335 | 0.1599 | 0.0037 | 0.0949 | 0.0025 | 0.0609 | 0.0000 | 0.0334 | 0.0002 | 0.0000 | 0.0002 | 0.0003 | 0.0019 | 0.0016 | 0.0087 | 0.0077 | 0.0523 | 0.0454 | 0.0796 | 0.0732 | 0.0596 | 0.0497 | 0.0965 | 0.0851 | 0.7010 | 0.7371 | 0.0006 | 0.0002 | 0.0008 | 0.0018 | 0.0020 | 0.0042 | 0.0140 | 0.0178 | 0.0566 | 0.0567 | 0.1052 | 0.1144 | 0.0708 | 0.0696 | 0.1036 | 0.1054 | 0.6462 | 0.6299 | 0.0002 | 0.0004 | 0.0019 | 0.0113 | 0.0550 | 0.0902 | 0.0700 | 0.1005 | 0.6706 | |||
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 742 | 248 | 1325 | 5484 | 955.8 | 428.77 | 8.01 | 2.97 | 481 | 526 | 610 | 705 | 833 | 1020 | 1224 | 1418 | 1627 | 0.0857 | 470 | 0.902 | 36.72 | 12.08 | 1 | 0.0823 | 109 | 0.0016 | 81.60 | 6.699 | 0.1744 | 1100000.0 | 1440000000 | 2060000000000 | 3.12E+15 | 0.3703 | 0.2538 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0110 | 0.0015 | 0.1801 | 0.0682 | 0.2904 | 0.1091 | 0.1360 | 0.0636 | 0.1324 | 0.1197 | 0.2500 | 0.6348 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0000 | 0.0360 | 0.0308 | 0.0596 | 0.0473 | 0.0263 | 0.0226 | 0.0526 | 0.0473 | 0.8241 | 0.8520 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0022 | 0.0128 | 0.0511 | 0.0511 | 0.0644 | 0.0831 | 0.0378 | 0.0511 | 0.0578 | 0.0895 | 0.7867 | 0.7093 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0417 | 0.0609 | 0.0330 | 0.0557 | 0.8070 | 5 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 12 | 0.0134 | 9.32 | 4.700 | 0.3378 | 73.0 | 745.296 | 8414.3 | 103808 | 0.4557 | 0.1834 | 0.0246 | 0.0007 | 0.0780 | 0.0051 | 0.1560 | 0.0156 | 0.2275 | 0.0356 | 0.2236 | 0.0749 | 0.1629 | 0.1318 | 0.0948 | 0.2083 | 0.0289 | 0.2962 | 0.0039 | 0.2318 | 0.0045 | 0.0000 | 0.0206 | 0.0000 | 0.0448 | 0.0044 | 0.0775 | 0.0143 | 0.1104 | 0.0457 | 0.1205 | 0.0733 | 0.1415 | 0.1199 | 0.1700 | 0.2262 | 0.3102 | 0.5161 | 0.0910 | 0.1312 | 0.0842 | 0.1131 | 0.0910 | 0.1508 | 0.1045 | 0.1146 | 0.1270 | 0.1071 | 0.1222 | 0.1056 | 0.1283 | 0.1071 | 0.1236 | 0.0920 | 0.1283 | 0.0784 | 0.0246 | 0.0667 | 0.0896 | 0.1051 | 0.0958 | 0.1127 | 0.1221 | 0.1629 | 0.2206 | |
BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 270 | 229 | 650 | 7025 | 1251.1 | 283.87 | 11.58 | 3.56 | 859 | 957 | 1050 | 1150 | 1249 | 1356 | 1450 | 1553 | 1640 | 0.0757 | 532 | 1.003 | 35.47 | 12.37 | 1 | 0.1554 | 101 | 0.0018 | 76.01 | 6.355 | 0.1286 | 1650000.0 | 2260000000 | 3210000000000 | 4.71E+15 | 0.3546 | 0.2714 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0030 | 0.0000 | 0.0861 | 0.0357 | 0.1632 | 0.0683 | 0.0950 | 0.0233 | 0.1424 | 0.0714 | 0.5104 | 0.8012 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0405 | 0.0356 | 0.0729 | 0.0681 | 0.0304 | 0.0232 | 0.0547 | 0.0464 | 0.7996 | 0.8266 | 0.0000 | 1.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0127 | 0.0000 | 0.0828 | 0.0000 | 0.1083 | 0.0000 | 0.0573 | 0.0000 | 0.1083 | 0.0000 | 0.6306 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0093 | 0.0556 | 0.0710 | 0.0525 | 0.0556 | 0.7562 | 7 | 9 | 10 | 11 | 11 | 12 | 13 | 14 | 16 | 0.0081 | 16.06 | 5.190 | 0.2777 | 146.9 | 2017.49 | 29808.4 | 471003 | 0.4942 | 0.1529 | 0.0108 | 0.0007 | 0.0396 | 0.0047 | 0.0930 | 0.0132 | 0.1508 | 0.0346 | 0.2124 | 0.0636 | 0.2362 | 0.1307 | 0.1635 | 0.2187 | 0.0792 | 0.3144 | 0.0144 | 0.2194 | 0.0046 | 0.0002 | 0.0197 | 0.0029 | 0.0427 | 0.0088 | 0.0534 | 0.0212 | 0.0813 | 0.0412 | 0.1242 | 0.0726 | 0.1697 | 0.1078 | 0.2247 | 0.2453 | 0.2797 | 0.5001 | 0.1226 | 0.2147 | 0.1534 | 0.1587 | 0.1534 | 0.1635 | 0.1480 | 0.1346 | 0.1180 | 0.1010 | 0.0987 | 0.0737 | 0.0887 | 0.0561 | 0.0717 | 0.0657 | 0.0455 | 0.0321 | 0.0277 | 0.0639 | 0.0858 | 0.1141 | 0.1354 | 0.1515 | 0.1521 | 0.1263 | 0.1433 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1215 | 337 | 5299 | 15208 | 314.6 | 49.18 | 289.78 | 445.68 | 258 | 273 | 285 | 295 | 306 | 318 | 334 | 356 | 383 | 0.0592 | 900 | 0.916 | 116.83 | 42.76 | 1 | 0.0670 | 355 | 0.0017 | 23.16 | 6.655 | 0.2317 | 101403.0 | 33500000 | 11400000000 | 3950000000000 | 0.3986 | 0.2511 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0023 | 0.0000 | 0.0093 | 0.0002 | 0.0305 | 0.0140 | 0.0753 | 0.0305 | 0.0827 | 0.0190 | 0.1286 | 0.0295 | 0.6705 | 0.9068 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0033 | 0.0000 | 0.0158 | 0.0117 | 0.0404 | 0.0247 | 0.0404 | 0.0102 | 0.0640 | 0.0160 | 0.8348 | 0.9373 | 0.0063 | 0.0000 | 0.0158 | 0.0000 | 0.0412 | 0.0000 | 0.0824 | 0.0000 | 0.1173 | 0.0000 | 0.1347 | 0.0000 | 0.1094 | 0.0000 | 0.1410 | 0.0000 | 0.3518 | 0.0000 | 0.0022 | 0.0083 | 0.0188 | 0.0419 | 0.0777 | 0.1104 | 0.0877 | 0.1144 | 0.5386 | 14 | 17 | 20 | 24 | 37 | 96 | 310 | 568 | 955 | 0.0512 | 92.27 | 5.412 | 0.4889 | 282587.0 | 374000000 | 589000000000 | 1.04E+15 | 0.4260 | 0.2078 | 0.0678 | 0.0021 | 0.2554 | 0.0310 | 0.2713 | 0.1590 | 0.1515 | 0.1654 | 0.1154 | 0.1977 | 0.0736 | 0.1668 | 0.0375 | 0.0880 | 0.0202 | 0.0992 | 0.0072 | 0.0908 | 0.0000 | 0.0000 | 0.0002 | 0.0006 | 0.0006 | 0.0002 | 0.0058 | 0.0039 | 0.0392 | 0.0362 | 0.0676 | 0.0614 | 0.0464 | 0.0369 | 0.0642 | 0.0614 | 0.7760 | 0.7994 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0016 | 0.0038 | 0.0107 | 0.0111 | 0.0513 | 0.0494 | 0.0801 | 0.0970 | 0.0632 | 0.0688 | 0.0880 | 0.0932 | 0.7051 | 0.6762 | 0.0000 | 0.0000 | 0.0009 | 0.0068 | 0.0458 | 0.0717 | 0.0503 | 0.0824 | 0.7421 | |
BT-20 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 376 | 455 | 8612 | 19511 | 469.8 | 86.38 | 153.43 | 207.66 | 366 | 398 | 421 | 442 | 462 | 481 | 504 | 535 | 586 | 0.0560 | 1092 | 1.054 | 96.75 | 36.14 | 2 | 0.0303 | 261 | 0.0021 | 17.56 | 6.482 | 0.2579 | 228217.0 | 115000000 | 59600000000 | 32000000000000 | 0.4229 | 0.2282 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0013 | 0.0001 | 0.0076 | 0.0005 | 0.0416 | 0.0131 | 0.0841 | 0.0274 | 0.0978 | 0.0207 | 0.1278 | 0.0313 | 0.6396 | 0.9068 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0041 | 0.0000 | 0.0211 | 0.0100 | 0.0414 | 0.0175 | 0.0481 | 0.0110 | 0.0610 | 0.0179 | 0.8237 | 0.9436 | 0.0043 | 0.0036 | 0.0120 | 0.0109 | 0.0197 | 0.0217 | 0.0557 | 0.0833 | 0.1259 | 0.1304 | 0.1430 | 0.2319 | 0.1062 | 0.1196 | 0.1233 | 0.1159 | 0.4101 | 0.2826 | 0.0015 | 0.0043 | 0.0089 | 0.0317 | 0.0735 | 0.1259 | 0.1036 | 0.1315 | 0.5193 | 11 | 13 | 18 | 30 | 60 | 112 | 179 | 264 | 423 | 0.0683 | 25.53 | 5.187 | 0.5116 | 66658.4 | 44800000 | 39000000000 | 40100000000000 | 0.5736 | 0.1127 | 0.0353 | 0.0020 | 0.1686 | 0.0088 | 0.3001 | 0.0775 | 0.1811 | 0.1460 | 0.1407 | 0.2098 | 0.0974 | 0.2095 | 0.0444 | 0.1320 | 0.0256 | 0.1163 | 0.0068 | 0.0981 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0009 | 0.0008 | 0.0093 | 0.0073 | 0.0635 | 0.0515 | 0.0934 | 0.0789 | 0.0696 | 0.0596 | 0.1069 | 0.0928 | 0.6562 | 0.7087 | 0.0009 | 0.0006 | 0.0016 | 0.0028 | 0.0024 | 0.0028 | 0.0164 | 0.0188 | 0.0739 | 0.0858 | 0.1294 | 0.1377 | 0.0880 | 0.0928 | 0.1272 | 0.1341 | 0.5603 | 0.5246 | 0.0002 | 0.0006 | 0.0021 | 0.0135 | 0.0685 | 0.1068 | 0.0784 | 0.1212 | 0.6087 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 509 | 507 | 7824 | 25276 | 555.9 | 107.56 | 87.69 | 105.95 | 423 | 462 | 493 | 518 | 545 | 575 | 609 | 649 | 706 | 0.0436 | 1102 | 1.007 | 126.85 | 35.51 | 1 | 0.0387 | 303 | 0.0006 | 69.54 | 7.651 | 0.1417 | 320582.0 | 192000000 | 118000000000 | 75400000000000 | 0.3901 | 0.2585 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0078 | 0.0004 | 0.0495 | 0.0148 | 0.1105 | 0.0312 | 0.1156 | 0.0262 | 0.1566 | 0.0356 | 0.5585 | 0.8919 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0027 | 0.0000 | 0.0235 | 0.0112 | 0.0491 | 0.0226 | 0.0541 | 0.0132 | 0.0699 | 0.0177 | 0.7998 | 0.9352 | 0.0031 | 0.0092 | 0.0086 | 0.0323 | 0.0163 | 0.0276 | 0.0467 | 0.1198 | 0.1346 | 0.1935 | 0.1486 | 0.2166 | 0.1121 | 0.1106 | 0.1307 | 0.1290 | 0.3992 | 0.1613 | 0.0008 | 0.0025 | 0.0044 | 0.0227 | 0.0729 | 0.1111 | 0.1003 | 0.1279 | 0.5575 | 8 | 10 | 12 | 19 | 41 | 74 | 111 | 159 | 230 | 0.0557 | 17.43 | 5.062 | 0.4981 | 18913.8 | 5940000 | 2360000000 | 1110000000000 | 0.5214 | 0.1569 | 0.0217 | 0.0010 | 0.1318 | 0.0082 | 0.2484 | 0.0573 | 0.1624 | 0.1006 | 0.1628 | 0.1863 | 0.1092 | 0.2103 | 0.0691 | 0.1325 | 0.0507 | 0.1178 | 0.0438 | 0.1859 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0013 | 0.0003 | 0.0090 | 0.0059 | 0.0434 | 0.0366 | 0.0864 | 0.0707 | 0.0600 | 0.0485 | 0.0853 | 0.0637 | 0.7144 | 0.7741 | 0.0004 | 0.0001 | 0.0010 | 0.0009 | 0.0023 | 0.0038 | 0.0153 | 0.0204 | 0.0611 | 0.0695 | 0.1126 | 0.1258 | 0.0774 | 0.0886 | 0.1029 | 0.1191 | 0.6271 | 0.5718 | 0.0000 | 0.0001 | 0.0020 | 0.0125 | 0.0561 | 0.0967 | 0.0714 | 0.0968 | 0.6644 | |||
BT-20 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1048 | 708 | 5142 | 24738 | 301.9 | 68.07 | 109.84 | 172.01 | 222 | 242 | 260 | 277 | 294 | 311 | 331 | 357 | 392 | 0.0388 | 959 | 0.968 | 116.28 | 25.18 | 1 | 0.0492 | 253 | 0.0006 | 71.96 | 7.550 | 0.1408 | 95756.4 | 31900000 | 11200000000 | 4100000000000 | 0.4570 | 0.1935 | 0.0003 | 0.0000 | 0.0013 | 0.0000 | 0.0047 | 0.0000 | 0.0216 | 0.0019 | 0.0748 | 0.0214 | 0.1430 | 0.0387 | 0.1596 | 0.0406 | 0.1790 | 0.0601 | 0.4156 | 0.8373 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0082 | 0.0000 | 0.0378 | 0.0149 | 0.0692 | 0.0253 | 0.0736 | 0.0188 | 0.0862 | 0.0339 | 0.7226 | 0.9070 | 0.0043 | 0.0069 | 0.0096 | 0.0069 | 0.0246 | 0.0138 | 0.0769 | 0.0897 | 0.1143 | 0.1655 | 0.1357 | 0.1483 | 0.1026 | 0.1621 | 0.1303 | 0.1345 | 0.4017 | 0.2724 | 0.0009 | 0.0009 | 0.0082 | 0.0359 | 0.0848 | 0.1107 | 0.1086 | 0.1302 | 0.5199 | 8 | 9 | 10 | 12 | 15 | 23 | 92 | 222 | 376 | 0.2071 | 21.28 | 4.079 | 0.6284 | 41652.0 | 21000000 | 12200000000 | 7930000000000 | 0.5079 | 0.1266 | 0.0955 | 0.0067 | 0.2888 | 0.0516 | 0.2966 | 0.2331 | 0.1382 | 0.1992 | 0.0843 | 0.1815 | 0.0618 | 0.1415 | 0.0247 | 0.0705 | 0.0079 | 0.0494 | 0.0022 | 0.0666 | 0.0000 | 0.0001 | 0.0005 | 0.0000 | 0.0009 | 0.0007 | 0.0081 | 0.0081 | 0.0426 | 0.0385 | 0.0742 | 0.0621 | 0.0481 | 0.0470 | 0.0763 | 0.0643 | 0.7492 | 0.7792 | 0.0003 | 0.0005 | 0.0011 | 0.0016 | 0.0032 | 0.0042 | 0.0113 | 0.0130 | 0.0493 | 0.0504 | 0.0852 | 0.0895 | 0.0569 | 0.0606 | 0.0833 | 0.0935 | 0.7095 | 0.6868 | 0.0003 | 0.0007 | 0.0018 | 0.0119 | 0.0426 | 0.0802 | 0.0555 | 0.0798 | 0.7272 | |
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 936 | 824 | 6449 | 21481 | 423.4 | 94.11 | 65.04 | 80.19 | 317 | 342 | 363 | 384 | 406 | 430 | 462 | 503 | 558 | 0.0487 | 1047 | 0.994 | 112.45 | 43.42 | 1 | 0.0482 | 311 | 0.0009 | 45.87 | 7.285 | 0.1707 | 188113.0 | 87800000 | 42900000000 | 22000000000000 | 0.4226 | 0.2238 | 0.0002 | 0.0000 | 0.0005 | 0.0002 | 0.0027 | 0.0002 | 0.0178 | 0.0020 | 0.0677 | 0.0179 | 0.1322 | 0.0358 | 0.1404 | 0.0349 | 0.1777 | 0.0545 | 0.4607 | 0.8547 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0013 | 0.0000 | 0.0066 | 0.0000 | 0.0301 | 0.0114 | 0.0587 | 0.0202 | 0.0584 | 0.0129 | 0.0904 | 0.0227 | 0.7539 | 0.9328 | 0.0032 | 0.0026 | 0.0097 | 0.0129 | 0.0130 | 0.0206 | 0.0536 | 0.0851 | 0.1218 | 0.2010 | 0.1404 | 0.1469 | 0.1055 | 0.1392 | 0.1502 | 0.1624 | 0.4026 | 0.2294 | 0.0011 | 0.0054 | 0.0058 | 0.0307 | 0.0719 | 0.1135 | 0.0973 | 0.1135 | 0.5607 | 6 | 8 | 10 | 14 | 26 | 50 | 85 | 121 | 172 | 0.0959 | 7.90 | 4.467 | 0.5774 | 10661.1 | 2560000 | 795000000 | 304000000000 | 0.4718 | 0.1706 | 0.0377 | 0.0018 | 0.1636 | 0.0076 | 0.2796 | 0.0566 | 0.1975 | 0.1401 | 0.1494 | 0.2175 | 0.0821 | 0.2166 | 0.0488 | 0.1351 | 0.0309 | 0.1061 | 0.0105 | 0.1187 | 0.0006 | 0.0002 | 0.0000 | 0.0004 | 0.0002 | 0.0009 | 0.0077 | 0.0074 | 0.0426 | 0.0363 | 0.0686 | 0.0582 | 0.0524 | 0.0451 | 0.0781 | 0.0670 | 0.7499 | 0.7845 | 0.0000 | 0.0000 | 0.0000 | 0.0013 | 0.0019 | 0.0030 | 0.0108 | 0.0165 | 0.0583 | 0.0629 | 0.0853 | 0.0985 | 0.0701 | 0.0795 | 0.1004 | 0.1112 | 0.6732 | 0.6271 | 0.0000 | 0.0001 | 0.0014 | 0.0094 | 0.0487 | 0.0799 | 0.0555 | 0.0843 | 0.7206 | |||
BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 376 | 815 | 6277 | 23826 | 431.4 | 82.01 | 114.95 | 189.20 | 331 | 361 | 383 | 403 | 426 | 447 | 473 | 503 | 544 | 0.0434 | 1033 | 0.842 | 82.28 | 28.16 | 1 | 0.0394 | 247 | 0.0009 | 43.90 | 7.226 | 0.1745 | 192840.0 | 89200000 | 42600000000 | 20900000000000 | 0.4504 | 0.2050 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0030 | 0.0000 | 0.0159 | 0.0007 | 0.0597 | 0.0143 | 0.1101 | 0.0347 | 0.1238 | 0.0286 | 0.1574 | 0.0475 | 0.5295 | 0.8742 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0071 | 0.0000 | 0.0301 | 0.0117 | 0.0512 | 0.0268 | 0.0508 | 0.0136 | 0.0737 | 0.0265 | 0.7865 | 0.9214 | 0.0030 | 0.0329 | 0.0071 | 0.0197 | 0.0243 | 0.0526 | 0.0943 | 0.1645 | 0.1400 | 0.2368 | 0.1684 | 0.1711 | 0.1197 | 0.1184 | 0.1379 | 0.1184 | 0.3053 | 0.0855 | 0.0007 | 0.0023 | 0.0119 | 0.0250 | 0.0781 | 0.1153 | 0.0982 | 0.1255 | 0.5430 | 9 | 11 | 14 | 17 | 24 | 44 | 100 | 202 | 343 | 0.0536 | 32.28 | 4.983 | 0.5358 | 49009.5 | 35200000 | 34900000000 | 42600000000000 | 0.5156 | 0.1405 | 0.0766 | 0.0042 | 0.1959 | 0.0170 | 0.2844 | 0.1298 | 0.1485 | 0.1714 | 0.1248 | 0.1956 | 0.0821 | 0.1646 | 0.0450 | 0.0980 | 0.0269 | 0.1018 | 0.0158 | 0.1177 | 0.0000 | 0.0004 | 0.0003 | 0.0002 | 0.0023 | 0.0016 | 0.0088 | 0.0101 | 0.0504 | 0.0422 | 0.0802 | 0.0661 | 0.0538 | 0.0498 | 0.0854 | 0.0812 | 0.7189 | 0.7485 | 0.0003 | 0.0005 | 0.0008 | 0.0009 | 0.0041 | 0.0030 | 0.0112 | 0.0163 | 0.0573 | 0.0598 | 0.0870 | 0.0918 | 0.0671 | 0.0702 | 0.0950 | 0.1061 | 0.6771 | 0.6513 | 0.0006 | 0.0010 | 0.0016 | 0.0108 | 0.0544 | 0.0823 | 0.0603 | 0.0952 | 0.6936 | |||
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1039 | 222 | 8267 | 22106 | 288.0 | 59.05 | 151.11 | 185.59 | 216 | 238 | 254 | 269 | 282 | 298 | 314 | 336 | 366 | 0.0470 | 1038 | 1.207 | 123.17 | 44.29 | 1 | 0.0368 | 304 | 0.0006 | 72.43 | 7.591 | 0.1414 | 86440.9 | 27000000 | 8770000000 | 2960000000000 | 0.4619 | 0.1920 | 0.0002 | 0.0000 | 0.0011 | 0.0000 | 0.0049 | 0.0001 | 0.0163 | 0.0014 | 0.0611 | 0.0158 | 0.1248 | 0.0327 | 0.1394 | 0.0332 | 0.1689 | 0.0503 | 0.4834 | 0.8666 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0049 | 0.0000 | 0.0290 | 0.0113 | 0.0560 | 0.0195 | 0.0638 | 0.0161 | 0.0864 | 0.0281 | 0.7592 | 0.9250 | 0.0044 | 0.0122 | 0.0059 | 0.0122 | 0.0344 | 0.0459 | 0.0659 | 0.0979 | 0.1553 | 0.2049 | 0.1919 | 0.2141 | 0.1114 | 0.1070 | 0.1495 | 0.1346 | 0.2813 | 0.1713 | 0.0026 | 0.0018 | 0.0099 | 0.0342 | 0.0861 | 0.1315 | 0.1084 | 0.1380 | 0.4874 | 12 | 15 | 17 | 24 | 55 | 118 | 196 | 294 | 424 | 0.0394 | 36.87 | 5.514 | 0.4378 | 57275.2 | 29300000 | 17900000000 | 12400000000000 | 0.4786 | 0.1762 | 0.0641 | 0.0023 | 0.1929 | 0.0255 | 0.2734 | 0.1224 | 0.1781 | 0.1756 | 0.1168 | 0.1948 | 0.0851 | 0.1693 | 0.0556 | 0.1219 | 0.0221 | 0.0910 | 0.0119 | 0.0973 | 0.0001 | 0.0000 | 0.0005 | 0.0005 | 0.0019 | 0.0008 | 0.0100 | 0.0091 | 0.0516 | 0.0439 | 0.0899 | 0.0793 | 0.0692 | 0.0605 | 0.0927 | 0.0806 | 0.6841 | 0.7253 | 0.0014 | 0.0005 | 0.0020 | 0.0011 | 0.0047 | 0.0047 | 0.0137 | 0.0179 | 0.0676 | 0.0722 | 0.1069 | 0.1192 | 0.0847 | 0.0896 | 0.1139 | 0.1168 | 0.6051 | 0.5781 | 0.0001 | 0.0011 | 0.0038 | 0.0118 | 0.0592 | 0.1021 | 0.0731 | 0.1069 | 0.6419 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 898 | 503 | 7597 | 15942 | 143.4 | 27.73 | 173.50 | 120.68 | 110 | 119 | 126 | 132 | 140 | 148 | 157 | 168 | 183 | 0.0661 | 1053 | 1.190 | 84.90 | 37.16 | 1 | 0.0309 | 235 | 0.0025 | 15.67 | 6.274 | 0.2752 | 21329.9 | 3290000 | 525000000 | 86500000000 | 0.4372 | 0.2078 | 0.0006 | 0.0000 | 0.0010 | 0.0000 | 0.0046 | 0.0001 | 0.0191 | 0.0007 | 0.0570 | 0.0136 | 0.1188 | 0.0324 | 0.1394 | 0.0300 | 0.1797 | 0.0527 | 0.4799 | 0.8705 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0096 | 0.0000 | 0.0278 | 0.0107 | 0.0488 | 0.0198 | 0.0578 | 0.0112 | 0.0842 | 0.0195 | 0.7694 | 0.9388 | 0.0070 | 0.0409 | 0.0141 | 0.0591 | 0.0273 | 0.0955 | 0.0703 | 0.1955 | 0.1453 | 0.2727 | 0.1641 | 0.1500 | 0.1258 | 0.0545 | 0.1516 | 0.0864 | 0.2945 | 0.0455 | 0.0017 | 0.0034 | 0.0095 | 0.0337 | 0.0685 | 0.1129 | 0.1067 | 0.1314 | 0.5322 | 41 | 69 | 95 | 120 | 148 | 179 | 215 | 264 | 340 | 0.0019 | 36.17 | 6.887 | 0.2809 | 44665.2 | 14900000 | 5940000000 | 2730000000000 | 0.4612 | 0.1723 | 0.0167 | 0.0012 | 0.0841 | 0.0062 | 0.1709 | 0.0303 | 0.1727 | 0.0682 | 0.1885 | 0.1425 | 0.1471 | 0.1913 | 0.0984 | 0.1576 | 0.0707 | 0.1542 | 0.0507 | 0.2485 | 0.0012 | 0.0005 | 0.0036 | 0.0018 | 0.0077 | 0.0047 | 0.0185 | 0.0109 | 0.0606 | 0.0516 | 0.1144 | 0.0972 | 0.0887 | 0.0746 | 0.1158 | 0.0983 | 0.5895 | 0.6604 | 0.0006 | 0.0021 | 0.0065 | 0.0130 | 0.0156 | 0.0199 | 0.0449 | 0.0483 | 0.1050 | 0.1174 | 0.1463 | 0.1612 | 0.1156 | 0.1174 | 0.1360 | 0.1333 | 0.4295 | 0.3874 | 0.0013 | 0.0034 | 0.0091 | 0.0235 | 0.0795 | 0.1362 | 0.1016 | 0.1281 | 0.5171 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 219 | 287 | 7728 | 17407 | 156.2 | 33.25 | 151.14 | 137.62 | 117 | 127 | 135 | 144 | 153 | 161 | 171 | 184 | 201 | 0.0567 | 987 | 1.201 | 93.64 | 34.53 | 3 | 0.0299 | 231 | 0.0018 | 24.55 | 6.611 | 0.2248 | 25514.2 | 4360000 | 778000000 | 145000000000 | 0.3633 | 0.2904 | 0.0006 | 0.0000 | 0.0024 | 0.0001 | 0.0054 | 0.0000 | 0.0261 | 0.0015 | 0.0755 | 0.0144 | 0.1309 | 0.0416 | 0.1551 | 0.0359 | 0.1992 | 0.0585 | 0.4049 | 0.8479 | 0.0002 | 0.0000 | 0.0014 | 0.0000 | 0.0028 | 0.0000 | 0.0126 | 0.0000 | 0.0327 | 0.0093 | 0.0547 | 0.0253 | 0.0662 | 0.0117 | 0.0973 | 0.0232 | 0.7321 | 0.9304 | 0.0082 | 0.0229 | 0.0202 | 0.0229 | 0.0306 | 0.0430 | 0.0866 | 0.1891 | 0.1262 | 0.1834 | 0.1688 | 0.2092 | 0.1494 | 0.1117 | 0.1501 | 0.1060 | 0.2599 | 0.1117 | 0.0017 | 0.0053 | 0.0122 | 0.0344 | 0.0780 | 0.1005 | 0.1089 | 0.1414 | 0.5176 | 25 | 37 | 53 | 75 | 105 | 143 | 192 | 255 | 344 | 0.0048 | 46.59 | 6.610 | 0.3171 | 41782.2 | 15900000 | 7490000000 | 4110000000000 | 0.4349 | 0.1994 | 0.0438 | 0.0012 | 0.1710 | 0.0129 | 0.2590 | 0.0915 | 0.1689 | 0.1419 | 0.1480 | 0.1792 | 0.0966 | 0.1929 | 0.0651 | 0.1402 | 0.0336 | 0.1134 | 0.0140 | 0.1269 | 0.0006 | 0.0000 | 0.0016 | 0.0011 | 0.0035 | 0.0031 | 0.0209 | 0.0133 | 0.0660 | 0.0570 | 0.1224 | 0.0997 | 0.0905 | 0.0754 | 0.1165 | 0.0996 | 0.5779 | 0.6509 | 0.0004 | 0.0013 | 0.0043 | 0.0044 | 0.0077 | 0.0109 | 0.0342 | 0.0455 | 0.0992 | 0.1166 | 0.1564 | 0.1705 | 0.1123 | 0.1236 | 0.1422 | 0.1484 | 0.4433 | 0.3789 | 0.0009 | 0.0019 | 0.0058 | 0.0251 | 0.0859 | 0.1396 | 0.1007 | 0.1336 | 0.5064 |