High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 969 | 728 | 16378 | 49009 | 195.5 | 37.68 | 203.96 | 331.62 | 151 | 169 | 180 | 189 | 198 | 206 | 215 | 226 | 241 | 0.0278 | 1362 | 1.188 | 93.09 | 34.48 | 1 | 0.0143 | 235 | 0.0032 | 12.80 | 6.161 | 0.3225 | 39638.5 | 8270000 | 1770000000 | 387000000000 | 0.4222 | 0.2262 | 0.0002 | 0.0000 | 0.0012 | 0.0000 | 0.0037 | 0.0000 | 0.0129 | 0.0003 | 0.0346 | 0.0080 | 0.0661 | 0.0181 | 0.0824 | 0.0160 | 0.1152 | 0.0268 | 0.6836 | 0.9309 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0036 | 0.0001 | 0.0120 | 0.0068 | 0.0260 | 0.0139 | 0.0283 | 0.0069 | 0.0418 | 0.0107 | 0.8870 | 0.9616 | 0.0089 | 0.0576 | 0.0166 | 0.0995 | 0.0426 | 0.1047 | 0.0736 | 0.1780 | 0.1192 | 0.1937 | 0.1473 | 0.1675 | 0.1256 | 0.0733 | 0.1456 | 0.0890 | 0.3206 | 0.0366 | 0.0012 | 0.0027 | 0.0072 | 0.0202 | 0.0501 | 0.0834 | 0.0821 | 0.1197 | 0.6333 | 7 | 8 | 10 | 12 | 17 | 54 | 192 | 390 | 701 | 0.1432 | 35.53 | 4.788 | 0.5519 | 151568.0 | 149000000 | 169000000000 | 211000000000000 | 0.4292 | 0.2197 | 0.0529 | 0.0035 | 0.2034 | 0.0131 | 0.2775 | 0.1127 | 0.1544 | 0.1604 | 0.1262 | 0.2014 | 0.0909 | 0.1979 | 0.0516 | 0.1081 | 0.0322 | 0.1003 | 0.0110 | 0.1027 | 0.0001 | 0.0001 | 0.0003 | 0.0001 | 0.0010 | 0.0003 | 0.0081 | 0.0057 | 0.0395 | 0.0371 | 0.0691 | 0.0641 | 0.0487 | 0.0414 | 0.0700 | 0.0648 | 0.7633 | 0.7864 | 0.0004 | 0.0003 | 0.0011 | 0.0011 | 0.0028 | 0.0036 | 0.0129 | 0.0138 | 0.0452 | 0.0466 | 0.0753 | 0.0825 | 0.0565 | 0.0561 | 0.0729 | 0.0789 | 0.7329 | 0.7170 | 0.0001 | 0.0013 | 0.0022 | 0.0102 | 0.0423 | 0.0730 | 0.0512 | 0.0723 | 0.7473 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 923 | 749 | 18485 | 19144 | 337.4 | 48.91 | 148.53 | 162.19 | 268 | 300 | 318 | 331 | 344 | 355 | 367 | 380 | 396 | 0.0705 | 1349 | 1.142 | 100.72 | 39.20 | 2 | 0.0147 | 271 | 0.0025 | 9.90 | 6.327 | 0.3429 | 116234.0 | 40800000 | 14500000000 | 5230000000000 | 0.4218 | 0.2181 | 0.0005 | 0.0000 | 0.0012 | 0.0001 | 0.0027 | 0.0001 | 0.0083 | 0.0008 | 0.0174 | 0.0071 | 0.0285 | 0.0145 | 0.0316 | 0.0074 | 0.0551 | 0.0119 | 0.8546 | 0.9581 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0001 | 0.0022 | 0.0008 | 0.0085 | 0.0071 | 0.0136 | 0.0145 | 0.0122 | 0.0074 | 0.0186 | 0.0119 | 0.9443 | 0.9581 | 0.0326 | 0.0000 | 0.0692 | 0.0000 | 0.0794 | 0.0000 | 0.1090 | 0.0000 | 0.1517 | 0.0000 | 0.1415 | 0.0000 | 0.1395 | 0.0000 | 0.1446 | 0.0000 | 0.1324 | 0.0000 | 0.0028 | 0.0050 | 0.0091 | 0.0138 | 0.0293 | 0.0412 | 0.0457 | 0.0737 | 0.7793 | 23 | 31 | 42 | 57 | 77 | 109 | 167 | 256 | 387 | 0.0183 | 13.36 | 5.441 | 0.5104 | 48364.8 | 22700000 | 12800000000 | 8140000000000 | 0.3890 | 0.2609 | 0.0233 | 0.0013 | 0.0952 | 0.0085 | 0.1700 | 0.0530 | 0.1578 | 0.1011 | 0.1966 | 0.1512 | 0.1445 | 0.1702 | 0.0908 | 0.1386 | 0.0714 | 0.1404 | 0.0504 | 0.2358 | 0.0001 | 0.0003 | 0.0008 | 0.0009 | 0.0026 | 0.0044 | 0.0128 | 0.0124 | 0.0492 | 0.0417 | 0.0708 | 0.0661 | 0.0547 | 0.0448 | 0.0827 | 0.0706 | 0.7262 | 0.7587 | 0.0007 | 0.0006 | 0.0009 | 0.0017 | 0.0035 | 0.0058 | 0.0196 | 0.0235 | 0.0581 | 0.0707 | 0.0989 | 0.0946 | 0.0629 | 0.0773 | 0.0941 | 0.1006 | 0.6612 | 0.6252 | 0.0000 | 0.0010 | 0.0043 | 0.0159 | 0.0522 | 0.0864 | 0.0570 | 0.0870 | 0.6963 | |
Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 800 | 501 | 13792 | 38751 | 266.6 | 61.19 | 169.99 | 277.73 | 192 | 219 | 237 | 253 | 267 | 281 | 297 | 317 | 345 | 0.0391 | 1515 | 0.913 | 98.60 | 27.17 | 6 | 0.0188 | 259 | 0.0012 | 28.43 | 7.043 | 0.2221 | 74836.6 | 21900000 | 6660000000 | 2090000000000 | 0.4163 | 0.2227 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0034 | 0.0004 | 0.0145 | 0.0030 | 0.0508 | 0.0123 | 0.1000 | 0.0294 | 0.1083 | 0.0291 | 0.1428 | 0.0414 | 0.5789 | 0.8845 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0002 | 0.0051 | 0.0012 | 0.0181 | 0.0073 | 0.0381 | 0.0171 | 0.0415 | 0.0105 | 0.0570 | 0.0160 | 0.8387 | 0.9478 | 0.0032 | 0.0074 | 0.0083 | 0.0315 | 0.0221 | 0.0612 | 0.0437 | 0.1169 | 0.1095 | 0.1818 | 0.1536 | 0.1892 | 0.1312 | 0.1373 | 0.1276 | 0.1150 | 0.4009 | 0.1596 | 0.0001 | 0.0023 | 0.0069 | 0.0225 | 0.0520 | 0.0995 | 0.0920 | 0.1141 | 0.6107 | 11 | 14 | 16 | 21 | 32 | 62 | 139 | 285 | 553 | 0.1524 | 25.56 | 4.437 | 0.6078 | 106029.0 | 97600000 | 110000000000 | 141000000000000 | 0.3354 | 0.3305 | 0.0662 | 0.0027 | 0.2254 | 0.0240 | 0.2667 | 0.1419 | 0.1607 | 0.1818 | 0.1295 | 0.1818 | 0.0830 | 0.1829 | 0.0379 | 0.1071 | 0.0230 | 0.0916 | 0.0077 | 0.0861 | 0.0003 | 0.0003 | 0.0010 | 0.0006 | 0.0035 | 0.0021 | 0.0193 | 0.0153 | 0.0582 | 0.0549 | 0.0728 | 0.0726 | 0.0478 | 0.0442 | 0.0766 | 0.0719 | 0.7205 | 0.7381 | 0.0006 | 0.0007 | 0.0019 | 0.0018 | 0.0059 | 0.0059 | 0.0221 | 0.0258 | 0.0548 | 0.0602 | 0.0841 | 0.0861 | 0.0579 | 0.0644 | 0.0867 | 0.0924 | 0.6859 | 0.6628 | 0.0003 | 0.0015 | 0.0047 | 0.0221 | 0.0559 | 0.0766 | 0.0542 | 0.0790 | 0.7058 | |
SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 518 | 503 | 15648 | 56021 | 320.9 | 59.50 | 142.33 | 181.99 | 244 | 279 | 299 | 315 | 329 | 341 | 354 | 368 | 389 | 0.0239 | 1341 | 0.987 | 126.85 | 36.01 | 1 | 0.0202 | 316 | 0.0015 | 21.65 | 6.855 | 0.2488 | 106538.0 | 36300000 | 12600000000 | 4480000000000 | 0.4413 | 0.2040 | 0.0005 | 0.0000 | 0.0005 | 0.0000 | 0.0020 | 0.0000 | 0.0079 | 0.0003 | 0.0295 | 0.0078 | 0.0562 | 0.0157 | 0.0615 | 0.0104 | 0.0915 | 0.0162 | 0.7503 | 0.9496 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0023 | 0.0003 | 0.0109 | 0.0075 | 0.0242 | 0.0143 | 0.0210 | 0.0081 | 0.0316 | 0.0119 | 0.9098 | 0.9580 | 0.0090 | 0.0536 | 0.0157 | 0.0179 | 0.0336 | 0.1429 | 0.0745 | 0.2143 | 0.1272 | 0.1429 | 0.1557 | 0.1607 | 0.1429 | 0.1071 | 0.1597 | 0.0357 | 0.2818 | 0.1250 | 0.0008 | 0.0025 | 0.0050 | 0.0158 | 0.0410 | 0.0684 | 0.0815 | 0.0977 | 0.6873 | 8 | 10 | 12 | 18 | 51 | 108 | 178 | 269 | 424 | 0.1076 | 16.66 | 4.969 | 0.5393 | 53375.8 | 26600000 | 15300000000 | 9680000000000 | 0.3694 | 0.2725 | 0.0166 | 0.0013 | 0.1012 | 0.0060 | 0.2168 | 0.0361 | 0.1910 | 0.0912 | 0.1770 | 0.1724 | 0.1403 | 0.2115 | 0.0824 | 0.1547 | 0.0457 | 0.1475 | 0.0291 | 0.1792 | 0.0006 | 0.0002 | 0.0006 | 0.0006 | 0.0027 | 0.0015 | 0.0085 | 0.0065 | 0.0354 | 0.0299 | 0.0682 | 0.0565 | 0.0555 | 0.0459 | 0.0719 | 0.0641 | 0.7567 | 0.7947 | 0.0005 | 0.0005 | 0.0022 | 0.0022 | 0.0040 | 0.0048 | 0.0126 | 0.0154 | 0.0463 | 0.0551 | 0.0837 | 0.0934 | 0.0695 | 0.0743 | 0.0862 | 0.0911 | 0.6950 | 0.6633 | 0.0005 | 0.0017 | 0.0041 | 0.0114 | 0.0416 | 0.0737 | 0.0613 | 0.0797 | 0.7260 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 987 | 380 | 12791 | 25828 | 244.0 | 56.67 | 95.18 | 198.31 | 177 | 201 | 217 | 230 | 243 | 256 | 271 | 289 | 316 | 0.0428 | 1106 | 0.611 | 50.00 | 6.08 | 2 | 0.0081 | 104 | 0.0009 | 41.29 | 7.385 | 0.1837 | 62748.8 | 16900000 | 4720000000 | 1370000000000 | 0.4150 | 0.2225 | 0.0007 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0139 | 0.0020 | 0.0437 | 0.0128 | 0.0935 | 0.0267 | 0.1037 | 0.0271 | 0.1485 | 0.0436 | 0.5911 | 0.8877 | 0.0004 | 0.0000 | 0.0005 | 0.0000 | 0.0012 | 0.0000 | 0.0051 | 0.0007 | 0.0167 | 0.0075 | 0.0370 | 0.0142 | 0.0370 | 0.0105 | 0.0578 | 0.0186 | 0.8443 | 0.9484 | 0.0051 | 0.0074 | 0.0136 | 0.0297 | 0.0230 | 0.0408 | 0.0519 | 0.1169 | 0.0928 | 0.1447 | 0.1328 | 0.1855 | 0.0992 | 0.1039 | 0.1507 | 0.1169 | 0.4308 | 0.2542 | 0.0013 | 0.0041 | 0.0084 | 0.0209 | 0.0523 | 0.0900 | 0.0917 | 0.1156 | 0.6157 | 10 | 11 | 13 | 16 | 19 | 30 | 61 | 128 | 252 | 0.1445 | 34.06 | 4.024 | 0.6355 | 48384.8 | 50100000 | 70500000000 | 115000000000000 | 0.4211 | 0.2561 | 0.0753 | 0.0013 | 0.2507 | 0.0276 | 0.3011 | 0.1619 | 0.1172 | 0.1639 | 0.1051 | 0.2101 | 0.0717 | 0.1905 | 0.0362 | 0.0921 | 0.0291 | 0.0768 | 0.0135 | 0.0758 | 0.0001 | 0.0002 | 0.0003 | 0.0001 | 0.0021 | 0.0012 | 0.0147 | 0.0116 | 0.0679 | 0.0616 | 0.1162 | 0.1005 | 0.0657 | 0.0596 | 0.1024 | 0.0930 | 0.6306 | 0.6721 | 0.0002 | 0.0012 | 0.0012 | 0.0028 | 0.0041 | 0.0058 | 0.0225 | 0.0271 | 0.0797 | 0.0776 | 0.1234 | 0.1387 | 0.0808 | 0.0856 | 0.1154 | 0.1264 | 0.5727 | 0.5349 | 0.0002 | 0.0013 | 0.0034 | 0.0168 | 0.0750 | 0.1186 | 0.0738 | 0.1066 | 0.6045 | |||
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1097 | 888 | 12238 | 26075 | 289.7 | 37.50 | 189.36 | 227.04 | 244 | 259 | 270 | 279 | 288 | 297 | 306 | 319 | 339 | 0.0439 | 1145 | 0.830 | 88.09 | 22.20 | 1 | 0.0187 | 229 | 0.0028 | 13.76 | 6.262 | 0.2992 | 85311.3 | 25500000 | 7770000000 | 2410000000000 | 0.4323 | 0.2203 | 0.0001 | 0.0000 | 0.0006 | 0.0000 | 0.0020 | 0.0000 | 0.0060 | 0.0003 | 0.0185 | 0.0078 | 0.0396 | 0.0156 | 0.0439 | 0.0098 | 0.0748 | 0.0169 | 0.8146 | 0.9496 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0001 | 0.0111 | 0.0076 | 0.0227 | 0.0147 | 0.0220 | 0.0071 | 0.0372 | 0.0112 | 0.9046 | 0.9593 | 0.0133 | 0.0000 | 0.0200 | 0.0000 | 0.0333 | 0.0000 | 0.0765 | 0.0000 | 0.1109 | 0.0000 | 0.1408 | 0.0000 | 0.1264 | 0.0000 | 0.1574 | 0.0000 | 0.3215 | 0.0000 | 0.0025 | 0.0088 | 0.0142 | 0.0239 | 0.0616 | 0.0902 | 0.0999 | 0.1291 | 0.5696 | 14 | 17 | 21 | 38 | 82 | 149 | 243 | 368 | 535 | 0.0346 | 41.52 | 5.730 | 0.4531 | 87402.9 | 53700000 | 38800000000 | 31400000000000 | 0.4360 | 0.2156 | 0.0618 | 0.0023 | 0.2087 | 0.0236 | 0.2420 | 0.1370 | 0.1346 | 0.1541 | 0.1098 | 0.1754 | 0.0927 | 0.1578 | 0.0590 | 0.0979 | 0.0495 | 0.0906 | 0.0418 | 0.1614 | 0.0001 | 0.0003 | 0.0003 | 0.0006 | 0.0015 | 0.0013 | 0.0103 | 0.0092 | 0.0495 | 0.0407 | 0.0808 | 0.0715 | 0.0648 | 0.0501 | 0.0944 | 0.0787 | 0.6983 | 0.7478 | 0.0000 | 0.0003 | 0.0007 | 0.0015 | 0.0026 | 0.0033 | 0.0159 | 0.0223 | 0.0664 | 0.0710 | 0.1136 | 0.1319 | 0.0845 | 0.0978 | 0.1225 | 0.1311 | 0.5939 | 0.5409 | 0.0004 | 0.0007 | 0.0021 | 0.0134 | 0.0562 | 0.0948 | 0.0755 | 0.1060 | 0.6510 | |
Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 709 | 307 | 13145 | 33263 | 215.6 | 52.79 | 151.28 | 220.31 | 149 | 174 | 189 | 203 | 216 | 228 | 242 | 259 | 283 | 0.0407 | 1355 | 1.265 | 23.41 | 8.25 | 1 | 0.0043 | 57 | 0.0010 | 34.06 | 7.246 | 0.2053 | 49257.3 | 11800000 | 2960000000 | 769000000000 | 0.3831 | 0.2579 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0040 | 0.0005 | 0.0168 | 0.0025 | 0.0464 | 0.0130 | 0.0932 | 0.0319 | 0.1084 | 0.0316 | 0.1447 | 0.0480 | 0.5842 | 0.8725 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0014 | 0.0001 | 0.0053 | 0.0012 | 0.0169 | 0.0077 | 0.0331 | 0.0189 | 0.0378 | 0.0116 | 0.0514 | 0.0186 | 0.8537 | 0.9419 | 0.0054 | 0.0148 | 0.0050 | 0.0411 | 0.0204 | 0.0542 | 0.0549 | 0.1117 | 0.0976 | 0.1215 | 0.1187 | 0.1560 | 0.1145 | 0.1034 | 0.1287 | 0.1051 | 0.4549 | 0.2923 | 0.0014 | 0.0017 | 0.0065 | 0.0214 | 0.0510 | 0.0797 | 0.0892 | 0.1055 | 0.6436 | 12 | 15 | 20 | 31 | 50 | 92 | 148 | 246 | 442 | 0.0346 | 37.24 | 5.501 | 0.4820 | 71418.1 | 52500000 | 49100000000 | 54400000000000 | 0.4267 | 0.2463 | 0.0312 | 0.0012 | 0.1250 | 0.0165 | 0.2039 | 0.0728 | 0.1419 | 0.0958 | 0.1495 | 0.1578 | 0.1419 | 0.1887 | 0.0914 | 0.1192 | 0.0623 | 0.1242 | 0.0530 | 0.2238 | 0.0005 | 0.0003 | 0.0020 | 0.0009 | 0.0057 | 0.0031 | 0.0160 | 0.0110 | 0.0513 | 0.0476 | 0.0861 | 0.0794 | 0.0620 | 0.0504 | 0.0781 | 0.0712 | 0.6982 | 0.7362 | 0.0005 | 0.0004 | 0.0014 | 0.0037 | 0.0064 | 0.0063 | 0.0183 | 0.0174 | 0.0625 | 0.0699 | 0.1084 | 0.1182 | 0.0749 | 0.0836 | 0.1034 | 0.1020 | 0.6243 | 0.5984 | 0.0008 | 0.0015 | 0.0050 | 0.0158 | 0.0576 | 0.0968 | 0.0701 | 0.0894 | 0.6629 | |
MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 305 | 753 | 14531 | 31502 | 446.4 | 61.03 | 117.13 | 162.48 | 365 | 402 | 424 | 439 | 452 | 464 | 476 | 491 | 515 | 0.0488 | 1538 | 0.844 | 110.02 | 27.80 | 4 | 0.0189 | 274 | 0.0017 | 18.96 | 6.823 | 0.2707 | 202963.0 | 93800000 | 44000000000 | 21000000000000 | 0.4307 | 0.2135 | 0.0003 | 0.0001 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0036 | 0.0001 | 0.0149 | 0.0077 | 0.0284 | 0.0166 | 0.0253 | 0.0080 | 0.0383 | 0.0128 | 0.8882 | 0.9547 | 0.0001 | 0.0001 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0001 | 0.0098 | 0.0077 | 0.0186 | 0.0166 | 0.0149 | 0.0080 | 0.0188 | 0.0117 | 0.9360 | 0.9558 | 0.0148 | 1.0000 | 0.0239 | 0.0000 | 0.0091 | 0.0000 | 0.0262 | 0.0000 | 0.0809 | 0.0000 | 0.0945 | 0.0000 | 0.0809 | 0.0000 | 0.1173 | 0.0000 | 0.5524 | 0.0000 | 0.0022 | 0.0070 | 0.0123 | 0.0187 | 0.0346 | 0.0523 | 0.0642 | 0.0921 | 0.7167 | 13 | 16 | 21 | 33 | 52 | 79 | 118 | 180 | 305 | 0.0400 | 19.55 | 4.937 | 0.5597 | 40119.5 | 22800000 | 16800000000 | 14600000000000 | 0.4801 | 0.1897 | 0.0180 | 0.0019 | 0.0684 | 0.0102 | 0.1417 | 0.0304 | 0.1389 | 0.0605 | 0.1660 | 0.1385 | 0.1648 | 0.1775 | 0.1107 | 0.1263 | 0.1041 | 0.1394 | 0.0873 | 0.3154 | 0.0012 | 0.0003 | 0.0022 | 0.0020 | 0.0034 | 0.0030 | 0.0115 | 0.0124 | 0.0463 | 0.0387 | 0.0745 | 0.0614 | 0.0495 | 0.0472 | 0.0766 | 0.0656 | 0.7348 | 0.7694 | 0.0005 | 0.0007 | 0.0024 | 0.0020 | 0.0066 | 0.0068 | 0.0187 | 0.0217 | 0.0585 | 0.0622 | 0.0953 | 0.1084 | 0.0633 | 0.0699 | 0.0954 | 0.0979 | 0.6595 | 0.6304 | 0.0004 | 0.0017 | 0.0044 | 0.0151 | 0.0498 | 0.0888 | 0.0599 | 0.0831 | 0.6968 | |
MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 200 | 513 | 11296 | 11224 | 660.4 | 94.02 | 95.02 | 136.71 | 543 | 587 | 617 | 640 | 661 | 683 | 708 | 735 | 774 | 0.1009 | 1133 | 0.918 | 133.74 | 44.91 | 2 | 0.0313 | 353 | 0.0006 | 79.90 | 7.739 | 0.1635 | 444990.0 | 305000000 | 213000000000 | 152000000000000 | 0.4251 | 0.2228 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0017 | 0.0000 | 0.0042 | 0.0006 | 0.0187 | 0.0081 | 0.0399 | 0.0182 | 0.0436 | 0.0113 | 0.0656 | 0.0181 | 0.8257 | 0.9436 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0006 | 0.0000 | 0.0022 | 0.0004 | 0.0107 | 0.0077 | 0.0240 | 0.0167 | 0.0219 | 0.0084 | 0.0314 | 0.0139 | 0.9090 | 0.9530 | 0.0074 | 0.0816 | 0.0173 | 0.0204 | 0.0222 | 0.0408 | 0.0937 | 0.2245 | 0.0912 | 0.2245 | 0.1307 | 0.2041 | 0.1097 | 0.0816 | 0.1233 | 0.1224 | 0.4044 | 0.0000 | 0.0016 | 0.0026 | 0.0092 | 0.0209 | 0.0527 | 0.0772 | 0.0800 | 0.1071 | 0.6486 | 12 | 16 | 20 | 27 | 38 | 53 | 81 | 138 | 272 | 0.0564 | 8.94 | 4.344 | 0.6275 | 27717.6 | 13300000 | 8080000000 | 5720000000000 | 0.4886 | 0.1747 | 0.0110 | 0.0020 | 0.0386 | 0.0109 | 0.0684 | 0.0288 | 0.1323 | 0.0387 | 0.2183 | 0.1107 | 0.1940 | 0.1846 | 0.1147 | 0.1166 | 0.1422 | 0.1509 | 0.0805 | 0.3568 | 0.0009 | 0.0007 | 0.0031 | 0.0037 | 0.0037 | 0.0072 | 0.0119 | 0.0120 | 0.0417 | 0.0400 | 0.0716 | 0.0744 | 0.0409 | 0.0423 | 0.0707 | 0.0596 | 0.7555 | 0.7601 | 0.0008 | 0.0004 | 0.0011 | 0.0022 | 0.0042 | 0.0043 | 0.0168 | 0.0173 | 0.0348 | 0.0381 | 0.0880 | 0.0934 | 0.0513 | 0.0510 | 0.0677 | 0.0636 | 0.7353 | 0.7297 | 0.0007 | 0.0010 | 0.0036 | 0.0116 | 0.0416 | 0.0819 | 0.0459 | 0.0714 | 0.7423 | |
MCF7 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 828 | 486 | 14994 | 31048 | 470.7 | 84.93 | 145.23 | 202.56 | 364 | 398 | 424 | 447 | 469 | 490 | 513 | 542 | 583 | 0.0407 | 1265 | 1.143 | 89.20 | 33.84 | 2 | 0.0156 | 234 | 0.0008 | 39.09 | 7.354 | 0.1815 | 228773.0 | 115000000 | 59000000000 | 31200000000000 | 0.4389 | 0.2085 | 0.0001 | 0.0000 | 0.0001 | 0.0000 | 0.0020 | 0.0001 | 0.0111 | 0.0005 | 0.0411 | 0.0092 | 0.0890 | 0.0204 | 0.0990 | 0.0211 | 0.1268 | 0.0342 | 0.6308 | 0.9146 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0001 | 0.0049 | 0.0001 | 0.0183 | 0.0077 | 0.0417 | 0.0152 | 0.0417 | 0.0114 | 0.0544 | 0.0195 | 0.8381 | 0.9459 | 0.0048 | 0.0278 | 0.0077 | 0.0556 | 0.0191 | 0.1065 | 0.0689 | 0.1991 | 0.1411 | 0.2083 | 0.1689 | 0.1435 | 0.1325 | 0.0694 | 0.1536 | 0.1019 | 0.3033 | 0.0880 | 0.0004 | 0.0009 | 0.0068 | 0.0261 | 0.0682 | 0.1054 | 0.0961 | 0.1216 | 0.5745 | 6 | 8 | 10 | 13 | 30 | 83 | 171 | 296 | 457 | 0.1239 | 27.73 | 4.902 | 0.5414 | 62118.6 | 35000000 | 22900000000 | 16700000000000 | 0.4409 | 0.1994 | 0.0472 | 0.0018 | 0.1760 | 0.0086 | 0.2720 | 0.1069 | 0.1840 | 0.1494 | 0.1220 | 0.1901 | 0.0838 | 0.2070 | 0.0520 | 0.1123 | 0.0355 | 0.0968 | 0.0276 | 0.1271 | 0.0004 | 0.0000 | 0.0002 | 0.0003 | 0.0004 | 0.0005 | 0.0104 | 0.0070 | 0.0419 | 0.0383 | 0.0677 | 0.0587 | 0.0504 | 0.0418 | 0.0695 | 0.0619 | 0.7590 | 0.7915 | 0.0002 | 0.0002 | 0.0013 | 0.0006 | 0.0008 | 0.0007 | 0.0105 | 0.0168 | 0.0580 | 0.0609 | 0.0871 | 0.0932 | 0.0560 | 0.0646 | 0.0902 | 0.0922 | 0.6960 | 0.6707 | 0.0000 | 0.0003 | 0.0015 | 0.0114 | 0.0475 | 0.0781 | 0.0516 | 0.0805 | 0.7292 | |
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 472 | 365 | 10152 | 16333 | 306.6 | 57.54 | 224.30 | 196.37 | 237 | 256 | 271 | 285 | 301 | 317 | 336 | 357 | 386 | 0.0678 | 1107 | 0.822 | 136.62 | 44.05 | 1 | 0.0396 | 402 | 0.0006 | 77.66 | 7.651 | 0.1416 | 97320.9 | 31900000 | 10800000000 | 3780000000000 | 0.4559 | 0.2016 | 0.0007 | 0.0000 | 0.0006 | 0.0000 | 0.0038 | 0.0001 | 0.0147 | 0.0006 | 0.0559 | 0.0105 | 0.1218 | 0.0272 | 0.1337 | 0.0260 | 0.1584 | 0.0428 | 0.5103 | 0.8928 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0036 | 0.0001 | 0.0257 | 0.0079 | 0.0578 | 0.0184 | 0.0582 | 0.0109 | 0.0841 | 0.0197 | 0.7693 | 0.9430 | 0.0025 | 0.0159 | 0.0101 | 0.0518 | 0.0297 | 0.0876 | 0.0802 | 0.2072 | 0.1723 | 0.1952 | 0.1799 | 0.1474 | 0.1187 | 0.1036 | 0.1503 | 0.0558 | 0.2563 | 0.1355 | 0.0008 | 0.0025 | 0.0127 | 0.0317 | 0.0909 | 0.1254 | 0.1094 | 0.1379 | 0.4885 | 22 | 46 | 83 | 125 | 173 | 229 | 295 | 376 | 500 | 0.0068 | 69.26 | 6.886 | 0.2834 | 88869.9 | 46400000 | 29000000000 | 20500000000000 | 0.5451 | 0.1262 | 0.0275 | 0.0020 | 0.1405 | 0.0066 | 0.2540 | 0.0553 | 0.1753 | 0.1106 | 0.1531 | 0.1890 | 0.1086 | 0.2034 | 0.0715 | 0.1379 | 0.0376 | 0.1361 | 0.0319 | 0.1591 | 0.0004 | 0.0006 | 0.0004 | 0.0007 | 0.0035 | 0.0023 | 0.0163 | 0.0094 | 0.0680 | 0.0540 | 0.1119 | 0.0867 | 0.0864 | 0.0698 | 0.1192 | 0.1056 | 0.5940 | 0.6708 | 0.0002 | 0.0013 | 0.0020 | 0.0036 | 0.0087 | 0.0107 | 0.0296 | 0.0330 | 0.1018 | 0.1162 | 0.1498 | 0.1759 | 0.1073 | 0.1119 | 0.1433 | 0.1478 | 0.4572 | 0.3996 | 0.0004 | 0.0016 | 0.0045 | 0.0181 | 0.0879 | 0.1310 | 0.0994 | 0.1385 | 0.5186 | |
MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1123 | 700 | 12030 | 35050 | 359.5 | 76.99 | 172.29 | 212.34 | 266 | 289 | 311 | 331 | 350 | 372 | 398 | 428 | 469 | 0.0370 | 1298 | 1.080 | 120.07 | 37.70 | 1 | 0.0246 | 296 | 0.0007 | 42.37 | 7.437 | 0.1770 | 135186.0 | 53100000 | 21700000000 | 9200000000000 | 0.4257 | 0.2254 | 0.0007 | 0.0000 | 0.0024 | 0.0001 | 0.0047 | 0.0001 | 0.0166 | 0.0019 | 0.0578 | 0.0130 | 0.1117 | 0.0286 | 0.1278 | 0.0293 | 0.1729 | 0.0489 | 0.5054 | 0.8782 | 0.0001 | 0.0000 | 0.0007 | 0.0000 | 0.0021 | 0.0000 | 0.0074 | 0.0004 | 0.0263 | 0.0079 | 0.0509 | 0.0166 | 0.0541 | 0.0114 | 0.0771 | 0.0203 | 0.7814 | 0.9434 | 0.0031 | 0.0144 | 0.0096 | 0.0431 | 0.0206 | 0.0431 | 0.0477 | 0.1150 | 0.0984 | 0.1889 | 0.1164 | 0.1725 | 0.1067 | 0.1376 | 0.1474 | 0.1212 | 0.4501 | 0.1643 | 0.0022 | 0.0027 | 0.0087 | 0.0265 | 0.0634 | 0.0961 | 0.0890 | 0.1053 | 0.6061 | 8 | 10 | 16 | 35 | 74 | 134 | 219 | 336 | 490 | 0.0515 | 30.59 | 5.525 | 0.4509 | 74768.6 | 43400000 | 30000000000 | 23500000000000 | 0.4088 | 0.2228 | 0.0812 | 0.0029 | 0.2274 | 0.0275 | 0.2491 | 0.1801 | 0.1201 | 0.1627 | 0.1228 | 0.1764 | 0.0750 | 0.1525 | 0.0533 | 0.1018 | 0.0392 | 0.0801 | 0.0320 | 0.1161 | 0.0001 | 0.0001 | 0.0002 | 0.0004 | 0.0010 | 0.0009 | 0.0095 | 0.0074 | 0.0610 | 0.0504 | 0.1018 | 0.0884 | 0.0671 | 0.0617 | 0.1083 | 0.0895 | 0.6509 | 0.7012 | 0.0002 | 0.0002 | 0.0005 | 0.0005 | 0.0022 | 0.0037 | 0.0162 | 0.0203 | 0.0769 | 0.0888 | 0.1277 | 0.1338 | 0.0832 | 0.0898 | 0.1251 | 0.1318 | 0.5682 | 0.5312 | 0.0003 | 0.0002 | 0.0015 | 0.0144 | 0.0678 | 0.1109 | 0.0804 | 0.1157 | 0.6087 | |
MDA-MB-231 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 708 | 397 | 15447 | 27394 | 562.4 | 113.78 | 118.30 | 212.73 | 394 | 458 | 507 | 542 | 576 | 606 | 636 | 667 | 703 | 0.0495 | 1356 | 0.896 | 108.19 | 30.00 | 3 | 0.0188 | 291 | 0.0006 | 29.72 | 7.605 | 0.2191 | 329218.0 | 199000000 | 124000000000 | 78600000000000 | 0.3988 | 0.2308 | 0.0014 | 0.0000 | 0.0019 | 0.0001 | 0.0040 | 0.0004 | 0.0105 | 0.0011 | 0.0269 | 0.0087 | 0.0473 | 0.0169 | 0.0485 | 0.0102 | 0.0672 | 0.0157 | 0.7922 | 0.9469 | 0.0001 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0001 | 0.0023 | 0.0010 | 0.0107 | 0.0080 | 0.0188 | 0.0166 | 0.0160 | 0.0091 | 0.0204 | 0.0143 | 0.9310 | 0.9510 | 0.0029 | 0.0000 | 0.0095 | 0.0179 | 0.0147 | 0.0536 | 0.0297 | 0.1607 | 0.0612 | 0.1250 | 0.0718 | 0.1071 | 0.0872 | 0.2500 | 0.1213 | 0.1071 | 0.6015 | 0.1786 | 0.0008 | 0.0010 | 0.0032 | 0.0069 | 0.0226 | 0.0401 | 0.0411 | 0.0534 | 0.8309 | 7 | 9 | 10 | 11 | 12 | 15 | 40 | 206 | 467 | 0.3132 | 20.18 | 3.462 | 0.7115 | 59247.2 | 38200000 | 27600000000 | 21600000000000 | 0.5023 | 0.1444 | 0.0436 | 0.0036 | 0.1336 | 0.0128 | 0.2377 | 0.1026 | 0.1744 | 0.1354 | 0.1547 | 0.1810 | 0.1069 | 0.1882 | 0.0675 | 0.1055 | 0.0520 | 0.1119 | 0.0295 | 0.1589 | 0.0000 | 0.0003 | 0.0003 | 0.0004 | 0.0010 | 0.0004 | 0.0058 | 0.0038 | 0.0203 | 0.0189 | 0.0418 | 0.0353 | 0.0301 | 0.0220 | 0.0517 | 0.0418 | 0.8491 | 0.8771 | 0.0000 | 0.0000 | 0.0006 | 0.0005 | 0.0003 | 0.0005 | 0.0058 | 0.0079 | 0.0263 | 0.0302 | 0.0558 | 0.0631 | 0.0452 | 0.0492 | 0.0622 | 0.0705 | 0.8037 | 0.7782 | 0.0000 | 0.0000 | 0.0006 | 0.0049 | 0.0263 | 0.0486 | 0.0405 | 0.0571 | 0.8221 | |
MCF7 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 1162 | 577 | 13856 | 32218 | 412.2 | 88.94 | 164.83 | 232.07 | 304 | 336 | 360 | 380 | 402 | 425 | 452 | 487 | 537 | 0.0416 | 1339 | 1.120 | 120.08 | 40.36 | 1 | 0.0211 | 292 | 0.0008 | 47.91 | 7.432 | 0.1705 | 177845.0 | 80200000 | 37700000000 | 18400000000000 | 0.4301 | 0.2191 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0005 | 0.0112 | 0.0023 | 0.0595 | 0.0147 | 0.1409 | 0.0309 | 0.1350 | 0.0320 | 0.1666 | 0.0506 | 0.4830 | 0.8691 | 0.0002 | 0.0000 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0001 | 0.0264 | 0.0081 | 0.0665 | 0.0180 | 0.0589 | 0.0144 | 0.0831 | 0.0249 | 0.7596 | 0.9345 | 0.0043 | 0.0042 | 0.0036 | 0.0198 | 0.0213 | 0.0353 | 0.0588 | 0.0791 | 0.1113 | 0.1638 | 0.1552 | 0.1751 | 0.0991 | 0.1455 | 0.1204 | 0.1780 | 0.4260 | 0.1992 | 0.0009 | 0.0044 | 0.0096 | 0.0313 | 0.0768 | 0.1126 | 0.0944 | 0.1160 | 0.5540 | 7 | 9 | 11 | 18 | 43 | 99 | 192 | 328 | 498 | 0.0842 | 39.05 | 5.161 | 0.4769 | 81023.3 | 55900000 | 47700000000 | 47900000000000 | 0.4243 | 0.2283 | 0.1052 | 0.0021 | 0.2776 | 0.0324 | 0.3170 | 0.2034 | 0.1311 | 0.2094 | 0.0802 | 0.1990 | 0.0495 | 0.1459 | 0.0226 | 0.0876 | 0.0101 | 0.0631 | 0.0067 | 0.0571 | 0.0001 | 0.0001 | 0.0002 | 0.0002 | 0.0022 | 0.0012 | 0.0101 | 0.0092 | 0.0575 | 0.0513 | 0.1002 | 0.0842 | 0.0707 | 0.0637 | 0.1083 | 0.0944 | 0.6508 | 0.6958 | 0.0003 | 0.0007 | 0.0013 | 0.0009 | 0.0029 | 0.0034 | 0.0145 | 0.0165 | 0.0744 | 0.0808 | 0.1140 | 0.1269 | 0.0875 | 0.0901 | 0.1225 | 0.1277 | 0.5827 | 0.5529 | 0.0002 | 0.0008 | 0.0020 | 0.0126 | 0.0667 | 0.1066 | 0.0805 | 0.1167 | 0.6140 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 439 | 9462 | 17615 | 66.2 | 18.80 | 11.63 | 7.94 | 45 | 48 | 51 | 57 | 63 | 69 | 76 | 85 | 93 | 0.0582 | 1025 | 0.806 | 93.06 | 26.68 | 0 | 0.0260 | 246 | 0.0396 | 0.80 | 3.627 | 0.7208 | 4738.0 | 364637 | 29900000 | 2590000000 | 0.4090 | 0.2322 | 0.0114 | 0.0009 | 0.0137 | 0.0014 | 0.0190 | 0.0032 | 0.0307 | 0.0089 | 0.0497 | 0.0193 | 0.0678 | 0.0417 | 0.0898 | 0.0415 | 0.1269 | 0.0742 | 0.5909 | 0.8088 | 0.0052 | 0.0000 | 0.0064 | 0.0002 | 0.0081 | 0.0003 | 0.0109 | 0.0024 | 0.0165 | 0.0081 | 0.0215 | 0.0205 | 0.0284 | 0.0132 | 0.0370 | 0.0319 | 0.8659 | 0.9234 | 0.0061 | 0.0140 | 0.0065 | 0.0220 | 0.0105 | 0.0451 | 0.0252 | 0.0762 | 0.0304 | 0.1062 | 0.0527 | 0.1333 | 0.0641 | 0.1283 | 0.0933 | 0.1413 | 0.7112 | 0.3337 | 0.0026 | 0.0049 | 0.0086 | 0.0123 | 0.0283 | 0.0339 | 0.0416 | 0.0706 | 0.7972 | 5 | 6 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 0.2867 | 0.33 | 1.922 | 0.8442 | 198.3 | 4862.52 | 154893 | 5820000 | 0.5138 | 0.1400 | 0.0871 | 0.0128 | 0.1401 | 0.0280 | 0.1505 | 0.0586 | 0.1491 | 0.0912 | 0.1521 | 0.1375 | 0.1294 | 0.1665 | 0.1167 | 0.1770 | 0.0606 | 0.1781 | 0.0146 | 0.1503 | 0.0408 | 0.0059 | 0.0668 | 0.0174 | 0.0671 | 0.0381 | 0.0575 | 0.0614 | 0.0582 | 0.0937 | 0.0540 | 0.1156 | 0.0645 | 0.1142 | 0.0925 | 0.1136 | 0.4986 | 0.4402 | 0.0246 | 0.0157 | 0.0222 | 0.0242 | 0.0309 | 0.0310 | 0.0415 | 0.0336 | 0.0492 | 0.0529 | 0.0632 | 0.0663 | 0.0719 | 0.0777 | 0.1169 | 0.1326 | 0.5796 | 0.5660 | 0.0564 | 0.0389 | 0.0353 | 0.0306 | 0.0484 | 0.0603 | 0.0728 | 0.0984 | 0.5589 | |
Hs 578T | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 334 | 363 | 15302 | 41714 | 244.9 | 60.87 | 131.95 | 179.42 | 171 | 196 | 213 | 227 | 242 | 257 | 273 | 292 | 320 | 0.0338 | 1411 | 0.710 | 67.01 | 10.63 | 1 | 0.0092 | 141 | 0.0009 | 32.33 | 7.369 | 0.2155 | 63663.8 | 17500000 | 5040000000 | 1520000000000 | 0.3811 | 0.2520 | 0.0003 | 0.0001 | 0.0018 | 0.0001 | 0.0054 | 0.0012 | 0.0129 | 0.0025 | 0.0443 | 0.0131 | 0.0775 | 0.0277 | 0.0883 | 0.0259 | 0.1303 | 0.0318 | 0.6391 | 0.8975 | 0.0001 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0005 | 0.0043 | 0.0006 | 0.0157 | 0.0082 | 0.0271 | 0.0149 | 0.0311 | 0.0107 | 0.0502 | 0.0147 | 0.8688 | 0.9504 | 0.0040 | 0.0021 | 0.0074 | 0.0094 | 0.0148 | 0.0178 | 0.0415 | 0.0545 | 0.0820 | 0.1027 | 0.1180 | 0.1394 | 0.0981 | 0.1038 | 0.1164 | 0.1153 | 0.5177 | 0.4549 | 0.0010 | 0.0043 | 0.0084 | 0.0193 | 0.0357 | 0.0673 | 0.0704 | 0.0887 | 0.7048 | 13 | 17 | 21 | 29 | 47 | 80 | 136 | 229 | 381 | 0.0427 | 30.07 | 5.192 | 0.5095 | 49598.6 | 28100000 | 20000000000 | 16800000000000 | 0.3211 | 0.3337 | 0.0612 | 0.0021 | 0.1948 | 0.0183 | 0.2759 | 0.1123 | 0.1692 | 0.1501 | 0.1266 | 0.2025 | 0.0897 | 0.1912 | 0.0381 | 0.1170 | 0.0295 | 0.0975 | 0.0151 | 0.1089 | 0.0001 | 0.0001 | 0.0003 | 0.0005 | 0.0017 | 0.0013 | 0.0140 | 0.0104 | 0.0568 | 0.0497 | 0.0959 | 0.0827 | 0.0647 | 0.0548 | 0.0965 | 0.0855 | 0.6699 | 0.7149 | 0.0002 | 0.0004 | 0.0005 | 0.0012 | 0.0029 | 0.0045 | 0.0170 | 0.0211 | 0.0778 | 0.0843 | 0.1185 | 0.1332 | 0.0800 | 0.0874 | 0.1208 | 0.1226 | 0.5822 | 0.5453 | 0.0002 | 0.0013 | 0.0024 | 0.0139 | 0.0650 | 0.1091 | 0.0726 | 0.1074 | 0.6281 | |||
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 454 | 777 | 7409 | 17484 | 322.3 | 67.54 | 205.37 | 234.69 | 243 | 264 | 279 | 296 | 313 | 331 | 353 | 381 | 419 | 0.0565 | 988 | 1.214 | 100.09 | 46.32 | 1 | 0.0378 | 280 | 0.0005 | 88.54 | 7.749 | 0.1264 | 108444.0 | 38100000 | 13900000000 | 5270000000000 | 0.4118 | 0.2358 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0027 | 0.0000 | 0.0126 | 0.0013 | 0.0653 | 0.0133 | 0.1407 | 0.0324 | 0.1465 | 0.0319 | 0.1766 | 0.0542 | 0.4551 | 0.8669 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0010 | 0.0000 | 0.0040 | 0.0001 | 0.0306 | 0.0082 | 0.0657 | 0.0178 | 0.0679 | 0.0118 | 0.0977 | 0.0245 | 0.7329 | 0.9376 | 0.0029 | 0.0057 | 0.0029 | 0.0172 | 0.0155 | 0.0602 | 0.0472 | 0.0888 | 0.1282 | 0.1977 | 0.1643 | 0.1748 | 0.1157 | 0.1175 | 0.1400 | 0.1547 | 0.3832 | 0.1834 | 0.0024 | 0.0027 | 0.0054 | 0.0338 | 0.0764 | 0.1255 | 0.0940 | 0.1234 | 0.5364 | 11 | 14 | 17 | 31 | 88 | 192 | 303 | 420 | 566 | 0.0364 | 50.81 | 5.936 | 0.4194 | 97252.5 | 57300000 | 38200000000 | 27900000000000 | 0.4410 | 0.1792 | 0.0679 | 0.0012 | 0.2334 | 0.0148 | 0.3166 | 0.1561 | 0.1663 | 0.2149 | 0.0900 | 0.2129 | 0.0748 | 0.1752 | 0.0282 | 0.0907 | 0.0175 | 0.0767 | 0.0053 | 0.0576 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0013 | 0.0006 | 0.0070 | 0.0062 | 0.0449 | 0.0360 | 0.0791 | 0.0719 | 0.0574 | 0.0536 | 0.0936 | 0.0726 | 0.7161 | 0.7591 | 0.0000 | 0.0007 | 0.0007 | 0.0016 | 0.0023 | 0.0042 | 0.0126 | 0.0140 | 0.0555 | 0.0663 | 0.0963 | 0.1117 | 0.0864 | 0.0871 | 0.1164 | 0.1189 | 0.6299 | 0.5955 | 0.0003 | 0.0013 | 0.0012 | 0.0113 | 0.0518 | 0.0818 | 0.0742 | 0.1052 | 0.6728 | |
SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 406 | 653 | 9716 | 23603 | 431.9 | 88.96 | 349.44 | 405.84 | 326 | 380 | 406 | 425 | 442 | 459 | 475 | 495 | 525 | 0.0445 | 1051 | 1.155 | 114.98 | 44.01 | 1 | 0.0310 | 301 | 0.0009 | 57.02 | 7.395 | 0.1756 | 194415.0 | 90200000 | 42900000000 | 20900000000000 | 0.4256 | 0.2144 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0024 | 0.0002 | 0.0073 | 0.0009 | 0.0306 | 0.0101 | 0.0644 | 0.0220 | 0.0617 | 0.0172 | 0.1018 | 0.0289 | 0.7315 | 0.9207 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0014 | 0.0003 | 0.0115 | 0.0083 | 0.0248 | 0.0165 | 0.0200 | 0.0081 | 0.0331 | 0.0149 | 0.9091 | 0.9519 | 0.0122 | 0.0252 | 0.0157 | 0.0692 | 0.0332 | 0.0503 | 0.0752 | 0.1195 | 0.1461 | 0.2201 | 0.1785 | 0.1698 | 0.1400 | 0.0943 | 0.1417 | 0.1321 | 0.2572 | 0.1195 | 0.0002 | 0.0018 | 0.0031 | 0.0201 | 0.0458 | 0.0885 | 0.0915 | 0.1196 | 0.6294 | 11 | 15 | 26 | 74 | 177 | 311 | 477 | 692 | 979 | 0.0386 | 101.07 | 6.457 | 0.3962 | 286810.0 | 301000000 | 364000000000 | 491000000000000 | 0.5288 | 0.1335 | 0.0292 | 0.0023 | 0.1390 | 0.0075 | 0.2010 | 0.0674 | 0.1542 | 0.1168 | 0.1584 | 0.1632 | 0.1246 | 0.1791 | 0.0806 | 0.1344 | 0.0556 | 0.1290 | 0.0574 | 0.2002 | 0.0001 | 0.0001 | 0.0006 | 0.0003 | 0.0019 | 0.0007 | 0.0085 | 0.0046 | 0.0443 | 0.0358 | 0.0839 | 0.0706 | 0.0599 | 0.0519 | 0.0888 | 0.0796 | 0.7120 | 0.7564 | 0.0001 | 0.0003 | 0.0008 | 0.0014 | 0.0045 | 0.0043 | 0.0123 | 0.0170 | 0.0555 | 0.0621 | 0.1009 | 0.1122 | 0.0725 | 0.0814 | 0.1086 | 0.1185 | 0.6449 | 0.6027 | 0.0005 | 0.0014 | 0.0034 | 0.0121 | 0.0467 | 0.0905 | 0.0701 | 0.0917 | 0.6837 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 376 | 670 | 11475 | 30585 | 465.6 | 100.42 | 131.66 | 237.18 | 350 | 378 | 401 | 424 | 447 | 473 | 505 | 551 | 622 | 0.0430 | 1316 | 1.157 | 137.30 | 49.41 | 1 | 0.0297 | 341 | 0.0015 | 21.13 | 6.886 | 0.2666 | 226895.0 | 116000000 | 61700000000 | 34300000000000 | 0.4225 | 0.2239 | 0.0007 | 0.0000 | 0.0015 | 0.0002 | 0.0037 | 0.0005 | 0.0127 | 0.0019 | 0.0414 | 0.0147 | 0.0727 | 0.0296 | 0.0882 | 0.0265 | 0.1258 | 0.0409 | 0.6532 | 0.8857 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0014 | 0.0000 | 0.0059 | 0.0002 | 0.0182 | 0.0083 | 0.0338 | 0.0145 | 0.0420 | 0.0091 | 0.0610 | 0.0147 | 0.8365 | 0.9533 | 0.0028 | 0.0121 | 0.0080 | 0.0151 | 0.0099 | 0.0302 | 0.0274 | 0.0710 | 0.0690 | 0.1480 | 0.0922 | 0.1631 | 0.0813 | 0.1329 | 0.1068 | 0.1647 | 0.6026 | 0.2628 | 0.0008 | 0.0026 | 0.0051 | 0.0240 | 0.0431 | 0.0825 | 0.0785 | 0.0990 | 0.6644 | 5 | 6 | 8 | 9 | 12 | 26 | 86 | 218 | 471 | 0.1403 | 63.23 | 4.504 | 0.5576 | 73585.6 | 57500000 | 53700000000 | 56800000000000 | 0.4673 | 0.1625 | 0.0887 | 0.0045 | 0.2607 | 0.0499 | 0.2554 | 0.2123 | 0.1210 | 0.1544 | 0.1082 | 0.1653 | 0.0736 | 0.1423 | 0.0413 | 0.0927 | 0.0316 | 0.0855 | 0.0195 | 0.0931 | 0.0001 | 0.0000 | 0.0005 | 0.0003 | 0.0014 | 0.0003 | 0.0066 | 0.0066 | 0.0477 | 0.0419 | 0.0761 | 0.0690 | 0.0508 | 0.0460 | 0.0878 | 0.0763 | 0.7290 | 0.7595 | 0.0001 | 0.0001 | 0.0001 | 0.0010 | 0.0019 | 0.0016 | 0.0087 | 0.0121 | 0.0598 | 0.0631 | 0.0938 | 0.0985 | 0.0624 | 0.0744 | 0.1049 | 0.1107 | 0.6681 | 0.6384 | 0.0003 | 0.0003 | 0.0015 | 0.0081 | 0.0555 | 0.0813 | 0.0601 | 0.0971 | 0.6958 | |||
BT-20 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 826 | 707 | 7372 | 21148 | 252.5 | 53.79 | 169.89 | 208.84 | 187 | 203 | 217 | 232 | 247 | 263 | 279 | 299 | 324 | 0.0440 | 931 | 0.980 | 86.83 | 30.02 | 1 | 0.0311 | 229 | 0.0008 | 53.24 | 7.330 | 0.1651 | 66652.7 | 18400000 | 5290000000 | 1590000000000 | 0.4618 | 0.1983 | 0.0000 | 0.0000 | 0.0015 | 0.0001 | 0.0048 | 0.0000 | 0.0231 | 0.0016 | 0.0808 | 0.0131 | 0.1549 | 0.0265 | 0.1579 | 0.0260 | 0.1862 | 0.0450 | 0.3908 | 0.8876 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0017 | 0.0000 | 0.0101 | 0.0005 | 0.0353 | 0.0083 | 0.0679 | 0.0166 | 0.0713 | 0.0101 | 0.0901 | 0.0194 | 0.7234 | 0.9451 | 0.0023 | 0.0073 | 0.0083 | 0.0366 | 0.0264 | 0.0623 | 0.0746 | 0.1282 | 0.1432 | 0.1758 | 0.1907 | 0.1319 | 0.1311 | 0.1575 | 0.1409 | 0.0989 | 0.2826 | 0.2015 | 0.0003 | 0.0044 | 0.0075 | 0.0232 | 0.0786 | 0.1193 | 0.0987 | 0.1425 | 0.5255 | 10 | 12 | 15 | 27 | 67 | 141 | 237 | 331 | 459 | 0.0738 | 28.37 | 5.373 | 0.4963 | 72475.9 | 42400000 | 31000000000 | 26900000000000 | 0.4734 | 0.1923 | 0.0494 | 0.0029 | 0.2224 | 0.0070 | 0.3468 | 0.1140 | 0.1622 | 0.2051 | 0.0962 | 0.2533 | 0.0622 | 0.2019 | 0.0327 | 0.0889 | 0.0186 | 0.0625 | 0.0096 | 0.0644 | 0.0001 | 0.0001 | 0.0000 | 0.0000 | 0.0013 | 0.0007 | 0.0070 | 0.0057 | 0.0424 | 0.0396 | 0.0866 | 0.0755 | 0.0557 | 0.0466 | 0.0794 | 0.0711 | 0.7274 | 0.7607 | 0.0001 | 0.0000 | 0.0007 | 0.0005 | 0.0014 | 0.0028 | 0.0130 | 0.0161 | 0.0580 | 0.0627 | 0.1058 | 0.1260 | 0.0772 | 0.0841 | 0.1033 | 0.1156 | 0.6404 | 0.5922 | 0.0000 | 0.0009 | 0.0017 | 0.0096 | 0.0496 | 0.0965 | 0.0657 | 0.0897 | 0.6863 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 692 | 185 | 19415 | 44441 | 368.7 | 56.02 | 244.04 | 276.54 | 299 | 324 | 341 | 357 | 370 | 384 | 398 | 414 | 438 | 0.0403 | 1792 | 0.714 | 124.33 | 24.70 | 1 | 0.0157 | 305 | 0.0014 | 22.18 | 6.923 | 0.2357 | 139081.0 | 53500000 | 21000000000 | 8390000000000 | 0.4311 | 0.2269 | 0.0001 | 0.0000 | 0.0008 | 0.0001 | 0.0028 | 0.0001 | 0.0066 | 0.0002 | 0.0259 | 0.0087 | 0.0530 | 0.0182 | 0.0576 | 0.0109 | 0.0865 | 0.0176 | 0.7667 | 0.9443 | 0.0001 | 0.0000 | 0.0004 | 0.0001 | 0.0011 | 0.0001 | 0.0033 | 0.0002 | 0.0141 | 0.0084 | 0.0282 | 0.0172 | 0.0273 | 0.0090 | 0.0375 | 0.0134 | 0.8880 | 0.9517 | 0.0119 | 0.0000 | 0.0209 | 0.0000 | 0.0346 | 0.0000 | 0.0930 | 0.0000 | 0.1169 | 0.0000 | 0.1574 | 0.0000 | 0.1199 | 0.0000 | 0.1306 | 0.0000 | 0.3148 | 0.0000 | 0.0012 | 0.0035 | 0.0100 | 0.0254 | 0.0509 | 0.0848 | 0.0988 | 0.1192 | 0.6061 | 17 | 22 | 30 | 54 | 118 | 220 | 341 | 473 | 647 | 0.0281 | 44.65 | 6.124 | 0.4266 | 136024.0 | 100000000 | 87800000000 | 88300000000000 | 0.4534 | 0.1804 | 0.0700 | 0.0020 | 0.2411 | 0.0134 | 0.3304 | 0.1499 | 0.1469 | 0.1951 | 0.0898 | 0.2149 | 0.0610 | 0.1886 | 0.0354 | 0.0976 | 0.0173 | 0.0724 | 0.0080 | 0.0662 | 0.0003 | 0.0002 | 0.0010 | 0.0004 | 0.0018 | 0.0013 | 0.0092 | 0.0076 | 0.0506 | 0.0416 | 0.1014 | 0.0881 | 0.0667 | 0.0543 | 0.0944 | 0.0803 | 0.6746 | 0.7262 | 0.0007 | 0.0004 | 0.0014 | 0.0017 | 0.0031 | 0.0043 | 0.0147 | 0.0194 | 0.0670 | 0.0789 | 0.1259 | 0.1392 | 0.0883 | 0.0943 | 0.1136 | 0.1275 | 0.5852 | 0.5343 | 0.0001 | 0.0007 | 0.0030 | 0.0105 | 0.0587 | 0.1131 | 0.0775 | 0.1049 | 0.6315 | |
Hs 578T | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 960 | 785 | 14324 | 30146 | 220.1 | 48.30 | 124.97 | 184.42 | 157 | 180 | 197 | 210 | 222 | 234 | 246 | 262 | 280 | 0.0506 | 1525 | 1.218 | 105.55 | 39.82 | 5 | 0.0186 | 266 | 0.0010 | 36.62 | 7.236 | 0.1928 | 50767.5 | 12200000 | 3020000000 | 771000000000 | 0.3776 | 0.2614 | 0.0006 | 0.0000 | 0.0007 | 0.0000 | 0.0054 | 0.0001 | 0.0194 | 0.0010 | 0.0554 | 0.0114 | 0.1099 | 0.0262 | 0.1289 | 0.0281 | 0.1632 | 0.0425 | 0.5166 | 0.8907 | 0.0003 | 0.0000 | 0.0001 | 0.0000 | 0.0019 | 0.0000 | 0.0064 | 0.0003 | 0.0181 | 0.0084 | 0.0357 | 0.0167 | 0.0450 | 0.0127 | 0.0607 | 0.0189 | 0.8318 | 0.9430 | 0.0040 | 0.0182 | 0.0081 | 0.0286 | 0.0316 | 0.0909 | 0.0683 | 0.1506 | 0.1278 | 0.2052 | 0.1725 | 0.1740 | 0.1366 | 0.1117 | 0.1490 | 0.1039 | 0.3021 | 0.1169 | 0.0009 | 0.0031 | 0.0069 | 0.0208 | 0.0550 | 0.0930 | 0.1034 | 0.1315 | 0.5854 | 12 | 15 | 19 | 26 | 43 | 72 | 121 | 198 | 355 | 0.0673 | 18.66 | 4.787 | 0.5693 | 49625.5 | 32400000 | 28000000000 | 29100000000000 | 0.5089 | 0.1429 | 0.0634 | 0.0024 | 0.1947 | 0.0244 | 0.2245 | 0.1272 | 0.1694 | 0.1268 | 0.1346 | 0.1704 | 0.0969 | 0.1796 | 0.0580 | 0.1221 | 0.0414 | 0.1040 | 0.0170 | 0.1433 | 0.0006 | 0.0003 | 0.0017 | 0.0012 | 0.0033 | 0.0024 | 0.0152 | 0.0164 | 0.0709 | 0.0583 | 0.1015 | 0.0909 | 0.0701 | 0.0625 | 0.1026 | 0.0863 | 0.6341 | 0.6818 | 0.0001 | 0.0007 | 0.0023 | 0.0034 | 0.0068 | 0.0081 | 0.0275 | 0.0324 | 0.0863 | 0.0889 | 0.1257 | 0.1296 | 0.0840 | 0.0940 | 0.1076 | 0.1098 | 0.5596 | 0.5331 | 0.0005 | 0.0014 | 0.0043 | 0.0212 | 0.0766 | 0.1127 | 0.0825 | 0.1069 | 0.5940 | |
BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 | |
MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 489 | 834 | 12111 | 18609 | 541.6 | 118.52 | 168.67 | 182.80 | 399 | 441 | 476 | 505 | 532 | 559 | 589 | 628 | 690 | 0.0564 | 1049 | 1.226 | 127.68 | 55.00 | 1 | 0.0283 | 343 | 0.0010 | 25.57 | 7.191 | 0.2311 | 307350.0 | 183000000 | 114000000000 | 74500000000000 | 0.4223 | 0.2210 | 0.0002 | 0.0001 | 0.0011 | 0.0003 | 0.0035 | 0.0002 | 0.0121 | 0.0018 | 0.0351 | 0.0123 | 0.0639 | 0.0223 | 0.0770 | 0.0188 | 0.1064 | 0.0282 | 0.7006 | 0.9161 | 0.0002 | 0.0000 | 0.0007 | 0.0001 | 0.0017 | 0.0002 | 0.0050 | 0.0010 | 0.0150 | 0.0084 | 0.0268 | 0.0140 | 0.0306 | 0.0093 | 0.0434 | 0.0135 | 0.8767 | 0.9536 | 0.0032 | 0.0045 | 0.0053 | 0.0061 | 0.0150 | 0.0151 | 0.0513 | 0.0363 | 0.0898 | 0.0802 | 0.1165 | 0.1104 | 0.1010 | 0.0726 | 0.1112 | 0.1104 | 0.5067 | 0.5643 | 0.0016 | 0.0023 | 0.0060 | 0.0213 | 0.0499 | 0.0789 | 0.0809 | 0.1040 | 0.6550 | 8 | 14 | 27 | 56 | 102 | 159 | 227 | 312 | 435 | 0.0253 | 65.01 | 6.264 | 0.3576 | 61863.3 | 30100000 | 17400000000 | 11500000000000 | 0.4777 | 0.1891 | 0.0835 | 0.0023 | 0.2306 | 0.0249 | 0.2838 | 0.1678 | 0.1513 | 0.1698 | 0.1153 | 0.1751 | 0.0782 | 0.1769 | 0.0402 | 0.1114 | 0.0146 | 0.0964 | 0.0026 | 0.0755 | 0.0004 | 0.0001 | 0.0000 | 0.0000 | 0.0005 | 0.0009 | 0.0147 | 0.0085 | 0.0655 | 0.0544 | 0.1197 | 0.0976 | 0.0848 | 0.0670 | 0.1186 | 0.1038 | 0.5959 | 0.6678 | 0.0000 | 0.0007 | 0.0011 | 0.0021 | 0.0057 | 0.0062 | 0.0239 | 0.0327 | 0.0959 | 0.1092 | 0.1534 | 0.1697 | 0.1026 | 0.1133 | 0.1390 | 0.1561 | 0.4782 | 0.4101 | 0.0001 | 0.0000 | 0.0024 | 0.0177 | 0.0832 | 0.1361 | 0.0944 | 0.1341 | 0.5320 | |||
BT-20 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 267 | 437 | 13592 | 31269 | 301.0 | 63.57 | 169.76 | 203.21 | 225 | 246 | 263 | 279 | 295 | 313 | 331 | 353 | 386 | 0.0450 | 1407 | 0.991 | 116.62 | 32.28 | 1 | 0.0211 | 287 | 0.0005 | 80.82 | 7.811 | 0.1322 | 94652.1 | 31000000 | 10600000000 | 3760000000000 | 0.4501 | 0.1998 | 0.0000 | 0.0000 | 0.0006 | 0.0002 | 0.0033 | 0.0002 | 0.0168 | 0.0009 | 0.0656 | 0.0133 | 0.1325 | 0.0320 | 0.1576 | 0.0360 | 0.1861 | 0.0572 | 0.4376 | 0.8603 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0016 | 0.0001 | 0.0063 | 0.0004 | 0.0276 | 0.0084 | 0.0557 | 0.0188 | 0.0701 | 0.0154 | 0.0900 | 0.0249 | 0.7485 | 0.9321 | 0.0051 | 0.0171 | 0.0085 | 0.0240 | 0.0315 | 0.0719 | 0.0817 | 0.1199 | 0.1430 | 0.1747 | 0.1750 | 0.1695 | 0.1222 | 0.0925 | 0.1384 | 0.1318 | 0.2946 | 0.1986 | 0.0011 | 0.0024 | 0.0080 | 0.0318 | 0.0799 | 0.1235 | 0.1033 | 0.1392 | 0.5107 | 16 | 20 | 25 | 36 | 65 | 122 | 216 | 331 | 478 | 0.0295 | 54.42 | 5.957 | 0.4239 | 70109.3 | 38900000 | 25400000000 | 18600000000000 | 0.4659 | 0.1579 | 0.1220 | 0.0013 | 0.3239 | 0.0267 | 0.3147 | 0.2497 | 0.1092 | 0.2318 | 0.0683 | 0.1799 | 0.0358 | 0.1321 | 0.0147 | 0.0764 | 0.0073 | 0.0559 | 0.0041 | 0.0461 | 0.0003 | 0.0001 | 0.0008 | 0.0004 | 0.0024 | 0.0013 | 0.0139 | 0.0099 | 0.0651 | 0.0580 | 0.1046 | 0.0910 | 0.0733 | 0.0686 | 0.1102 | 0.1024 | 0.6295 | 0.6682 | 0.0002 | 0.0003 | 0.0011 | 0.0020 | 0.0039 | 0.0045 | 0.0192 | 0.0256 | 0.0810 | 0.0887 | 0.1246 | 0.1262 | 0.0858 | 0.0977 | 0.1320 | 0.1374 | 0.5522 | 0.5175 | 0.0001 | 0.0012 | 0.0027 | 0.0147 | 0.0721 | 0.1162 | 0.0811 | 0.1158 | 0.5962 |