High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 350 | 768 | | 2148 | 7377 | 649.8 | 190.42 | 59.61 | 108.11 | 361 | 467 | 544 | 624 | 689 | 729 | 767 | 811 | 863 | 0.0729 | 538 | 0.439 | 61.06 | 9.22 | 3 | 0.0791 | 170 | 0.0009 | 72.75 | 7.161 | 0.1651 | 458473.0 | 344000000 | 270000000000 | 221000000000000 | 0.4160 | 0.2058 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0050 | 0.0006 | 0.0291 | 0.0023 | 0.0824 | 0.0283 | 0.1568 | 0.0702 | 0.1075 | 0.0385 | 0.1397 | 0.0645 | 0.4794 | 0.7957 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0045 | 0.0016 | 0.0293 | 0.0240 | 0.0560 | 0.0464 | 0.0350 | 0.0235 | 0.0592 | 0.0427 | 0.8160 | 0.8617 | 0.0000 | 0.0094 | 0.0000 | 0.0283 | 0.0035 | 0.0189 | 0.0260 | 0.0566 | 0.0781 | 0.1415 | 0.1163 | 0.2264 | 0.0885 | 0.0472 | 0.1250 | 0.1038 | 0.5625 | 0.3679 | 0.0000 | 0.0000 | 0.0000 | 0.0091 | 0.0432 | 0.0639 | 0.0490 | 0.0763 | 0.7585 | 7 | 9 | 11 | 13 | 16 | 21 | 32 | 64 | 203 | 0.0746 | 10.49 | 3.983 | 0.6307 | 15239.4 | 6560000 | 3660000000 | 2420000000000 | 0.2920 | 0.3302 | 0.0000 | 0.0050 | 0.0655 | 0.0113 | 0.2143 | 0.0239 | 0.2292 | 0.0642 | 0.2054 | 0.1597 | 0.1429 | 0.2013 | 0.0774 | 0.1660 | 0.0506 | 0.1698 | 0.0149 | 0.1987 | 0.0000 | 0.0019 | 0.0017 | 0.0043 | 0.0040 | 0.0038 | 0.0115 | 0.0125 | 0.0340 | 0.0355 | 0.0530 | 0.0485 | 0.0363 | 0.0384 | 0.0594 | 0.0677 | 0.8000 | 0.7872 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0043 | 0.0031 | 0.0129 | 0.0109 | 0.0372 | 0.0427 | 0.0558 | 0.0637 | 0.0393 | 0.0365 | 0.0629 | 0.0637 | 0.7877 | 0.7793 | 0.0000 | 0.0000 | 0.0007 | 0.0170 | 0.0352 | 0.0483 | 0.0463 | 0.0614 | 0.7911 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 927 | 522 | | 3614 | 6289 | 297.5 | 144.28 | 59.44 | 77.60 | 127 | 157 | 192 | 233 | 266 | 305 | 406 | 465 | 511 | 0.1040 | 654 | 1.229 | 109.25 | 47.52 | 2 | 0.0819 | 296 | 0.0028 | 6.07 | 6.131 | 0.4083 | 109347.0 | 45800000 | 20700000000 | 9820000000000 | 0.3640 | 0.2549 | 0.0012 | 0.0000 | 0.0012 | 0.0006 | 0.0036 | 0.0025 | 0.0324 | 0.0086 | 0.1032 | 0.0531 | 0.1429 | 0.0834 | 0.1273 | 0.0562 | 0.1020 | 0.0828 | 0.4862 | 0.7128 | 0.0005 | 0.0000 | 0.0005 | 0.0004 | 0.0005 | 0.0015 | 0.0076 | 0.0030 | 0.0219 | 0.0203 | 0.0343 | 0.0263 | 0.0281 | 0.0192 | 0.0357 | 0.0312 | 0.8710 | 0.8980 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0039 | 0.0331 | 0.0347 | 0.0410 | 0.0597 | 0.0316 | 0.0414 | 0.0458 | 0.0462 | 0.8469 | 0.8141 | 0.0020 | 0.0013 | 0.0027 | 0.0054 | 0.0229 | 0.0404 | 0.0242 | 0.0310 | 0.8700 | 8 | 11 | 14 | 19 | 26 | 38 | 58 | 92 | 162 | 0.0962 | 2.42 | 3.459 | 0.6933 | 9553.8 | 2410000 | 755000000 | 271000000000 | 0.5400 | 0.1318 | 0.0018 | 0.0033 | 0.0126 | 0.0122 | 0.0650 | 0.0236 | 0.1733 | 0.0447 | 0.2365 | 0.0943 | 0.2166 | 0.1561 | 0.1480 | 0.1423 | 0.1137 | 0.1740 | 0.0325 | 0.3496 | 0.0000 | 0.0015 | 0.0005 | 0.0034 | 0.0032 | 0.0076 | 0.0142 | 0.0125 | 0.0500 | 0.0386 | 0.0866 | 0.0773 | 0.0596 | 0.0583 | 0.0830 | 0.0735 | 0.7030 | 0.7273 | 0.0000 | 0.0000 | 0.0012 | 0.0014 | 0.0037 | 0.0064 | 0.0197 | 0.0227 | 0.0614 | 0.0716 | 0.1020 | 0.1106 | 0.0694 | 0.0738 | 0.0860 | 0.0865 | 0.6566 | 0.6270 | 0.0011 | 0.0027 | 0.0043 | 0.0160 | 0.0543 | 0.1005 | 0.0660 | 0.0787 | 0.6766 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 765 | 448 | | 1036 | 4704 | 600.2 | 210.48 | 6.20 | 1.84 | 332 | 391 | 444 | 509 | 577 | 659 | 743 | 818 | 904 | 0.0897 | 422 | 1.225 | 53.31 | 21.95 | 1 | 0.1332 | 138 | 0.0016 | 24.08 | 6.554 | 0.2404 | 404516.0 | 298000000 | 234000000000 | 192000000000000 | 0.3419 | 0.2894 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0031 | 0.0043 | 0.1242 | 0.0558 | 0.2329 | 0.1016 | 0.1304 | 0.0629 | 0.1739 | 0.0801 | 0.3354 | 0.6938 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0392 | 0.0339 | 0.0633 | 0.0532 | 0.0271 | 0.0271 | 0.0542 | 0.0407 | 0.8163 | 0.8439 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0324 | 0.0585 | 0.0649 | 0.0848 | 0.1135 | 0.0409 | 0.0757 | 0.0673 | 0.0811 | 0.7427 | 0.6324 | 0.0000 | 0.0000 | 0.0021 | 0.0062 | 0.0374 | 0.0811 | 0.0395 | 0.0457 | 0.7879 | 4 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 0.0274 | 6.20 | 3.980 | 0.3875 | 41.8 | 302.145 | 2320.55 | 18932.6 | 0.4537 | 0.1856 | 0.0023 | 0.0005 | 0.0113 | 0.0013 | 0.0441 | 0.0090 | 0.1027 | 0.0249 | 0.1782 | 0.0542 | 0.2398 | 0.1111 | 0.2262 | 0.2325 | 0.1613 | 0.3262 | 0.0341 | 0.2402 | 0.0000 | 0.0000 | 0.0017 | 0.0005 | 0.0047 | 0.0016 | 0.0231 | 0.0099 | 0.0540 | 0.0309 | 0.1005 | 0.0574 | 0.1816 | 0.1030 | 0.3028 | 0.2870 | 0.3314 | 0.5097 | 0.1740 | 0.3416 | 0.2290 | 0.2805 | 0.1980 | 0.1584 | 0.1530 | 0.1041 | 0.1140 | 0.0679 | 0.0770 | 0.0181 | 0.0260 | 0.0158 | 0.0230 | 0.0090 | 0.0060 | 0.0045 | 0.0029 | 0.0141 | 0.0417 | 0.0959 | 0.1617 | 0.2172 | 0.2159 | 0.1543 | 0.0962 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 477 | 785 | | 2057 | 7126 | 15.8 | 5.35 | 5.58 | 1.94 | 10 | 11 | 13 | 14 | 15 | 16 | 18 | 20 | 22 | 0.1343 | 957 | 1.077 | 39.62 | 14.00 | 0 | 0.0501 | 103 | 0.0083 | 6.76 | 5.098 | 0.3940 | 278.8 | 5536.95 | 125712 | 3300000 | 0.3803 | 0.2578 | 0.0068 | 0.0000 | 0.0241 | 0.0017 | 0.0395 | 0.0081 | 0.0656 | 0.0237 | 0.1070 | 0.0317 | 0.1466 | 0.0531 | 0.1688 | 0.1073 | 0.2054 | 0.1604 | 0.2363 | 0.6140 | 0.0048 | 0.0000 | 0.0131 | 0.0010 | 0.0220 | 0.0068 | 0.0275 | 0.0167 | 0.0440 | 0.0256 | 0.0557 | 0.0329 | 0.0688 | 0.0605 | 0.0922 | 0.0924 | 0.6717 | 0.7641 | 0.0168 | 0.0437 | 0.0216 | 0.0437 | 0.0481 | 0.0328 | 0.0793 | 0.0656 | 0.0865 | 0.1038 | 0.1346 | 0.1093 | 0.1298 | 0.0710 | 0.1394 | 0.1749 | 0.3438 | 0.3552 | 0.0178 | 0.0231 | 0.0241 | 0.0409 | 0.0409 | 0.0682 | 0.0860 | 0.1091 | 0.5897 | 3 | 4 | 5 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0254 | 8.33 | 4.093 | 0.3635 | 34.9 | 237.89 | 1743 | 13611.8 | 0.5441 | 0.1416 | 0.0029 | 0.0002 | 0.0262 | 0.0017 | 0.0867 | 0.0113 | 0.1633 | 0.0354 | 0.2318 | 0.0789 | 0.2315 | 0.1447 | 0.1584 | 0.2575 | 0.0821 | 0.2968 | 0.0170 | 0.1734 | 0.0004 | 0.0002 | 0.0045 | 0.0006 | 0.0189 | 0.0043 | 0.0680 | 0.0220 | 0.1231 | 0.0509 | 0.2194 | 0.0876 | 0.2719 | 0.1709 | 0.2172 | 0.3403 | 0.0767 | 0.3232 | 0.2384 | 0.4990 | 0.3216 | 0.3638 | 0.2659 | 0.1113 | 0.1235 | 0.0258 | 0.0369 | 0.0000 | 0.0129 | 0.0000 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0115 | 0.0662 | 0.1649 | 0.2477 | 0.2359 | 0.1587 | 0.0825 | 0.0266 | 0.0059 |
| Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 992 | 554 | | 458 | 453 | 58.6 | 18.24 | 15.98 | 3.18 | 38 | 42 | 46 | 52 | 56 | 61 | 66 | 72 | 84 | 0.4040 | 183 | 0.735 | 110.07 | 27.07 | 1 | 0.6135 | 281 | 0.0119 | 5.25 | 4.713 | 0.4351 | 3769.0 | 265175 | 20300000 | 1680000000 | 0.3546 | 0.2594 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0448 | 0.0000 | 0.0597 | 0.0052 | 0.1294 | 0.0735 | 0.2139 | 0.1417 | 0.1791 | 0.0761 | 0.1343 | 0.1155 | 0.2189 | 0.5879 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0164 | 0.0046 | 0.0656 | 0.0371 | 0.1049 | 0.0928 | 0.0721 | 0.0278 | 0.0951 | 0.0603 | 0.6459 | 0.7773 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0096 | 0.0600 | 0.0673 | 0.1800 | 0.2019 | 0.1000 | 0.1731 | 0.2800 | 0.0865 | 0.1400 | 0.1635 | 0.0600 | 0.2885 | 0.1800 | 0.0000 | 0.0000 | 0.0048 | 0.0335 | 0.1435 | 0.1483 | 0.1100 | 0.1627 | 0.3971 | 12 | 13 | 14 | 15 | 16 | 17 | 17 | 18 | 20 | 0.8738 | 0.06 | 0.306 | 0.9702 | 265.5 | 4574.87 | 81636.7 | 1510000 | 0.5349 | 0.1049 | 0.0031 | 0.0000 | 0.0217 | 0.0000 | 0.0683 | 0.0046 | 0.1211 | 0.0207 | 0.2050 | 0.1359 | 0.1739 | 0.1544 | 0.1739 | 0.1613 | 0.1801 | 0.1521 | 0.0528 | 0.3710 | 0.0026 | 0.0000 | 0.0078 | 0.0000 | 0.0284 | 0.0045 | 0.0413 | 0.0089 | 0.1835 | 0.1250 | 0.1550 | 0.1473 | 0.1576 | 0.1518 | 0.1938 | 0.1384 | 0.2300 | 0.4241 | 0.2923 | 0.5000 | 0.1846 | 0.2143 | 0.1385 | 0.2143 | 0.1846 | 0.0714 | 0.1077 | 0.0000 | 0.0615 | 0.0000 | 0.0308 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0586 | 0.1328 | 0.1445 | 0.1758 | 0.1680 | 0.1367 | 0.1055 | 0.0586 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1140 | 501 | | 2795 | 5688 | 534.4 | 104.94 | 43.08 | 68.58 | 388 | 442 | 474 | 506 | 538 | 572 | 599 | 634 | 676 | 0.0939 | 534 | 0.836 | 78.23 | 21.02 | 2 | 0.0733 | 205 | 0.0014 | 24.71 | 6.757 | 0.2480 | 296615.0 | 170000000 | 100000000000 | 60500000000000 | 0.4327 | 0.2031 | 0.0000 | 0.0000 | 0.0022 | 0.0004 | 0.0017 | 0.0000 | 0.0094 | 0.0007 | 0.0409 | 0.0211 | 0.0819 | 0.0324 | 0.0658 | 0.0200 | 0.0946 | 0.0328 | 0.7035 | 0.8926 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0004 | 0.0000 | 0.0039 | 0.0007 | 0.0215 | 0.0211 | 0.0369 | 0.0324 | 0.0292 | 0.0200 | 0.0442 | 0.0298 | 0.8638 | 0.8956 | 0.0019 | 1.0000 | 0.0058 | 0.0000 | 0.0154 | 0.0000 | 0.0288 | 0.0000 | 0.0538 | 0.0000 | 0.1019 | 0.0000 | 0.0596 | 0.0000 | 0.0904 | 0.0000 | 0.6423 | 0.0000 | 0.0021 | 0.0014 | 0.0035 | 0.0174 | 0.0306 | 0.0542 | 0.0480 | 0.0618 | 0.7811 | 3 | 4 | 6 | 7 | 9 | 16 | 32 | 74 | 139 | 0.1144 | 4.30 | 3.672 | 0.6245 | 6558.9 | 1480000 | 411000000 | 131000000000 | 0.3466 | 0.2662 | 0.0039 | 0.0100 | 0.0656 | 0.0116 | 0.1467 | 0.0282 | 0.2625 | 0.0664 | 0.2625 | 0.1678 | 0.1931 | 0.1860 | 0.0618 | 0.1794 | 0.0039 | 0.1910 | 0.0000 | 0.1595 | 0.0006 | 0.0026 | 0.0012 | 0.0037 | 0.0000 | 0.0053 | 0.0078 | 0.0100 | 0.0246 | 0.0238 | 0.0414 | 0.0365 | 0.0402 | 0.0396 | 0.0618 | 0.0497 | 0.8224 | 0.8288 | 0.0000 | 0.0000 | 0.0007 | 0.0015 | 0.0007 | 0.0008 | 0.0092 | 0.0124 | 0.0348 | 0.0372 | 0.0540 | 0.0581 | 0.0511 | 0.0550 | 0.0724 | 0.0790 | 0.7770 | 0.7560 | 0.0000 | 0.0000 | 0.0026 | 0.0059 | 0.0315 | 0.0538 | 0.0446 | 0.0649 | 0.7967 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 946 | 911 | | 326 | 5218 | 83.2 | 12.55 | 6.61 | 2.23 | 66 | 72 | 76 | 80 | 84 | 87 | 90 | 94 | 100 | 0.0922 | 481 | 0.870 | 40.79 | 10.82 | 5 | 0.2883 | 94 | 0.0484 | 1.29 | 3.265 | 0.6193 | 7072.0 | 613833 | 54300000 | 4880000000 | 0.3970 | 0.2342 | 0.0039 | 0.0000 | 0.0039 | 0.0000 | 0.0078 | 0.0000 | 0.0310 | 0.0153 | 0.0698 | 0.0429 | 0.1512 | 0.0798 | 0.1163 | 0.0583 | 0.1860 | 0.0828 | 0.4302 | 0.7209 | 0.0034 | 0.0000 | 0.0000 | 0.0000 | 0.0069 | 0.0000 | 0.0206 | 0.0153 | 0.0309 | 0.0429 | 0.0997 | 0.0798 | 0.0550 | 0.0583 | 0.0928 | 0.0828 | 0.6907 | 0.7209 | 0.0303 | 0.0000 | 0.0909 | 0.0000 | 0.0909 | 0.0000 | 0.1818 | 0.0000 | 0.1818 | 0.0000 | 0.2121 | 0.0000 | 0.1212 | 0.0000 | 0.0606 | 0.0000 | 0.0303 | 0.0000 | 0.0055 | 0.0000 | 0.0110 | 0.0440 | 0.0714 | 0.1484 | 0.1154 | 0.2033 | 0.4011 | 4 | 5 | 6 | 6 | 6 | 7 | 7 | 9 | 9 | 0.0270 | 9.36 | 4.124 | 0.3431 | 48.6 | 391.422 | 3419.3 | 32319.8 | 0.5324 | 0.1461 | 0.0043 | 0.0011 | 0.0274 | 0.0040 | 0.0990 | 0.0214 | 0.1877 | 0.0631 | 0.2444 | 0.1213 | 0.2369 | 0.2069 | 0.1372 | 0.2618 | 0.0545 | 0.2256 | 0.0086 | 0.0948 | 0.0005 | 0.0002 | 0.0028 | 0.0019 | 0.0165 | 0.0091 | 0.0505 | 0.0369 | 0.1170 | 0.0831 | 0.1931 | 0.1470 | 0.2540 | 0.2323 | 0.2307 | 0.2820 | 0.1350 | 0.2075 | 0.1429 | 0.4528 | 0.2778 | 0.2397 | 0.2169 | 0.0896 | 0.1614 | 0.0557 | 0.0750 | 0.0436 | 0.0547 | 0.0533 | 0.0335 | 0.0412 | 0.0247 | 0.0194 | 0.0132 | 0.0048 | 0.0201 | 0.0768 | 0.1695 | 0.2209 | 0.1962 | 0.1531 | 0.0866 | 0.0497 | 0.0271 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 701 | 708 | | 3960 | 7704 | 112.0 | 31.81 | 223.51 | 163.62 | 75 | 85 | 93 | 101 | 108 | 116 | 126 | 138 | 157 | 0.0803 | 619 | 0.927 | 110.80 | 33.29 | 1 | 0.0717 | 284 | 0.0027 | 16.60 | 6.248 | 0.2945 | 13565.0 | 1760000 | 244000000 | 35800000000 | 0.4753 | 0.1844 | 0.0014 | 0.0003 | 0.0024 | 0.0003 | 0.0125 | 0.0015 | 0.0313 | 0.0063 | 0.1020 | 0.0328 | 0.1607 | 0.0671 | 0.1526 | 0.0632 | 0.1877 | 0.0933 | 0.3494 | 0.7353 | 0.0000 | 0.0000 | 0.0007 | 0.0003 | 0.0027 | 0.0008 | 0.0115 | 0.0032 | 0.0395 | 0.0171 | 0.0691 | 0.0338 | 0.0634 | 0.0261 | 0.0874 | 0.0389 | 0.7258 | 0.8798 | 0.0034 | 0.0025 | 0.0079 | 0.0101 | 0.0259 | 0.0226 | 0.0462 | 0.0955 | 0.1082 | 0.1583 | 0.1556 | 0.1935 | 0.1071 | 0.1332 | 0.1545 | 0.1734 | 0.3912 | 0.2111 | 0.0017 | 0.0022 | 0.0089 | 0.0279 | 0.0674 | 0.1070 | 0.0903 | 0.1260 | 0.5686 | 33 | 70 | 113 | 156 | 195 | 237 | 287 | 353 | 455 | 0.0025 | 36.71 | 6.898 | 0.2678 | 76724.5 | 33200000 | 16700000000 | 9360000000000 | 0.5297 | 0.1425 | 0.0044 | 0.0007 | 0.0481 | 0.0046 | 0.1665 | 0.0118 | 0.1506 | 0.0358 | 0.1715 | 0.1340 | 0.1696 | 0.1741 | 0.1247 | 0.1485 | 0.0873 | 0.1656 | 0.0772 | 0.3249 | 0.0002 | 0.0002 | 0.0022 | 0.0012 | 0.0038 | 0.0024 | 0.0134 | 0.0064 | 0.0475 | 0.0395 | 0.0913 | 0.0621 | 0.0726 | 0.0627 | 0.1012 | 0.0881 | 0.6677 | 0.7374 | 0.0019 | 0.0015 | 0.0039 | 0.0005 | 0.0085 | 0.0071 | 0.0324 | 0.0341 | 0.0772 | 0.0896 | 0.1127 | 0.1197 | 0.0888 | 0.1064 | 0.1011 | 0.1253 | 0.5735 | 0.5158 | 0.0003 | 0.0021 | 0.0063 | 0.0174 | 0.0683 | 0.1061 | 0.0920 | 0.1102 | 0.5974 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1301 | 922 | | 1366 | 2845 | 88.3 | 15.42 | 119.74 | 63.45 | 71 | 75 | 79 | 82 | 86 | 89 | 94 | 101 | 110 | 0.1547 | 440 | 0.932 | 89.36 | 30.02 | 1 | 0.1808 | 247 | 0.0068 | 9.05 | 5.271 | 0.3306 | 8028.3 | 753530 | 73100000 | 7320000000 | 0.4490 | 0.1982 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0058 | 0.0000 | 0.0164 | 0.0023 | 0.0733 | 0.0233 | 0.1485 | 0.0593 | 0.1736 | 0.0360 | 0.2343 | 0.0765 | 0.3481 | 0.8027 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0081 | 0.0022 | 0.0422 | 0.0205 | 0.0755 | 0.0490 | 0.0739 | 0.0190 | 0.1226 | 0.0381 | 0.6761 | 0.8712 | 0.0256 | 0.0303 | 0.0615 | 0.1515 | 0.0308 | 0.1515 | 0.1538 | 0.1212 | 0.1538 | 0.1515 | 0.1590 | 0.2121 | 0.1385 | 0.0909 | 0.1590 | 0.0606 | 0.1179 | 0.0303 | 0.0065 | 0.0114 | 0.0244 | 0.0603 | 0.0945 | 0.1222 | 0.1596 | 0.1417 | 0.3795 | 46 | 63 | 81 | 98 | 113 | 127 | 144 | 167 | 202 | 0.0075 | 7.31 | 5.265 | 0.4258 | 18362.3 | 3410000 | 742000000 | 186000000000 | 0.5900 | 0.1093 | 0.0045 | 0.0032 | 0.0465 | 0.0127 | 0.1213 | 0.0222 | 0.1122 | 0.0565 | 0.1655 | 0.1016 | 0.1565 | 0.1479 | 0.1565 | 0.1384 | 0.1168 | 0.1625 | 0.1202 | 0.3549 | 0.0000 | 0.0019 | 0.0063 | 0.0042 | 0.0091 | 0.0070 | 0.0223 | 0.0164 | 0.0566 | 0.0529 | 0.1189 | 0.0791 | 0.0840 | 0.0669 | 0.1309 | 0.0993 | 0.5720 | 0.6723 | 0.0046 | 0.0107 | 0.0092 | 0.0143 | 0.0288 | 0.0481 | 0.0714 | 0.1016 | 0.1429 | 0.1373 | 0.1705 | 0.1836 | 0.1244 | 0.1390 | 0.1244 | 0.1622 | 0.3237 | 0.2032 | 0.0000 | 0.0101 | 0.0155 | 0.0364 | 0.1006 | 0.1509 | 0.1223 | 0.1409 | 0.4234 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 305 | | 577 | 1224 | 107.4 | 19.71 | 5.63 | 1.94 | 82 | 89 | 96 | 101 | 108 | 113 | 118 | 125 | 133 | 0.2230 | 273 | 1.197 | 35.36 | 14.21 | 1 | 0.1664 | 96 | 0.0277 | 1.58 | 3.824 | 0.5880 | 11913.2 | 1360000 | 161000000 | 19400000000 | 0.3940 | 0.2372 | 0.0000 | 0.0000 | 0.0025 | 0.0000 | 0.0051 | 0.0000 | 0.0304 | 0.0018 | 0.0658 | 0.0406 | 0.1392 | 0.0689 | 0.1342 | 0.0548 | 0.1519 | 0.0707 | 0.4709 | 0.7633 | 0.0000 | 0.0000 | 0.0020 | 0.0000 | 0.0000 | 0.0000 | 0.0143 | 0.0017 | 0.0369 | 0.0399 | 0.0656 | 0.0624 | 0.0615 | 0.0295 | 0.0820 | 0.0503 | 0.7377 | 0.8163 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0968 | 0.6364 | 0.1290 | 0.1818 | 0.2796 | 0.0909 | 0.1075 | 0.0909 | 0.1398 | 0.0000 | 0.2473 | 0.0000 | 0.0034 | 0.0068 | 0.0169 | 0.0203 | 0.0811 | 0.0980 | 0.0743 | 0.0845 | 0.6149 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0263 | 7.62 | 3.939 | 0.3680 | 35.5 | 244.168 | 1810.28 | 14316.1 | 0.5714 | 0.1153 | 0.0047 | 0.0000 | 0.0712 | 0.0040 | 0.1377 | 0.0160 | 0.2389 | 0.0419 | 0.2358 | 0.1028 | 0.2294 | 0.1766 | 0.0585 | 0.2535 | 0.0190 | 0.2685 | 0.0047 | 0.1367 | 0.0000 | 0.0000 | 0.0154 | 0.0019 | 0.0475 | 0.0065 | 0.1342 | 0.0260 | 0.1853 | 0.0854 | 0.2601 | 0.1365 | 0.1936 | 0.2201 | 0.1211 | 0.2934 | 0.0428 | 0.2303 | 0.3190 | 0.5467 | 0.3667 | 0.3333 | 0.1571 | 0.1067 | 0.1238 | 0.0133 | 0.0286 | 0.0000 | 0.0048 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0280 | 0.1226 | 0.1559 | 0.1961 | 0.2259 | 0.1471 | 0.0753 | 0.0350 | 0.0140 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 516 | 891 | | 618 | 739 | 106.8 | 15.78 | 5.93 | 2.23 | 82 | 92 | 99 | 105 | 109 | 114 | 118 | 121 | 125 | 0.3234 | 239 | 1.055 | 76.24 | 24.70 | 1 | 0.3026 | 187 | 0.0261 | 2.24 | 3.925 | 0.5232 | 11645.2 | 1290000 | 146000000 | 16700000000 | 0.3863 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0358 | 0.0405 | 0.0875 | 0.0631 | 0.1093 | 0.0275 | 0.1590 | 0.0469 | 0.5885 | 0.8220 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0188 | 0.0000 | 0.0282 | 0.0405 | 0.0545 | 0.0631 | 0.0545 | 0.0275 | 0.0395 | 0.0469 | 0.8045 | 0.8220 | 0.1034 | 0.0000 | 0.2414 | 0.0000 | 0.2414 | 0.0000 | 0.2414 | 0.0000 | 0.1034 | 0.0000 | 0.0690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0277 | 0.0360 | 0.0305 | 0.0637 | 0.0665 | 0.1108 | 0.6648 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.5158 | 0.30 | 0.942 | 0.8384 | 40.2 | 298.797 | 2399.87 | 20613.1 | 0.4399 | 0.1643 | 0.0054 | 0.0000 | 0.0863 | 0.0054 | 0.1563 | 0.0342 | 0.3100 | 0.1081 | 0.2022 | 0.1856 | 0.1725 | 0.2270 | 0.0566 | 0.2378 | 0.0108 | 0.1640 | 0.0000 | 0.0378 | 0.0000 | 0.0000 | 0.0186 | 0.0016 | 0.0557 | 0.0188 | 0.1002 | 0.0518 | 0.1670 | 0.1256 | 0.2041 | 0.1680 | 0.2059 | 0.2135 | 0.1837 | 0.2370 | 0.0649 | 0.1837 | 0.1845 | 0.4878 | 0.2917 | 0.2195 | 0.2440 | 0.2195 | 0.2024 | 0.0732 | 0.0476 | 0.0000 | 0.0298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0213 | 0.0520 | 0.1348 | 0.1442 | 0.1891 | 0.1915 | 0.1277 | 0.1040 | 0.0355 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 919 | 900 | | 2948 | 8244 | 666.3 | 129.72 | 46.17 | 98.68 | 485 | 545 | 590 | 628 | 667 | 705 | 744 | 787 | 840 | 0.0761 | 627 | 1.113 | 69.64 | 24.02 | 1 | 0.0580 | 171 | 0.0007 | 51.40 | 7.349 | 0.1601 | 460748.0 | 329000000 | 243000000000 | 184000000000000 | 0.3935 | 0.2423 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0016 | 0.0000 | 0.0110 | 0.0014 | 0.0460 | 0.0183 | 0.0826 | 0.0341 | 0.0727 | 0.0251 | 0.1130 | 0.0389 | 0.6715 | 0.8822 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0000 | 0.0000 | 0.0041 | 0.0007 | 0.0202 | 0.0156 | 0.0326 | 0.0302 | 0.0223 | 0.0156 | 0.0396 | 0.0282 | 0.8808 | 0.9097 | 0.0019 | 0.0000 | 0.0039 | 0.0476 | 0.0273 | 0.0476 | 0.0253 | 0.1905 | 0.0916 | 0.2857 | 0.1443 | 0.1190 | 0.1033 | 0.2381 | 0.1618 | 0.0714 | 0.4405 | 0.0000 | 0.0007 | 0.0007 | 0.0027 | 0.0115 | 0.0392 | 0.0635 | 0.0581 | 0.0878 | 0.7360 | 9 | 11 | 12 | 14 | 16 | 21 | 28 | 43 | 87 | 0.1378 | 4.69 | 3.060 | 0.7458 | 11867.4 | 6550000 | 4590000000 | 3630000000000 | 0.6519 | 0.0809 | 0.0058 | 0.0114 | 0.0378 | 0.0178 | 0.0683 | 0.0242 | 0.1541 | 0.0604 | 0.1788 | 0.0768 | 0.1788 | 0.1230 | 0.1541 | 0.1393 | 0.1424 | 0.1628 | 0.0799 | 0.3845 | 0.0010 | 0.0064 | 0.0066 | 0.0092 | 0.0082 | 0.0104 | 0.0255 | 0.0249 | 0.0541 | 0.0385 | 0.0745 | 0.0686 | 0.0760 | 0.0735 | 0.1102 | 0.0951 | 0.6439 | 0.6732 | 0.0008 | 0.0018 | 0.0063 | 0.0055 | 0.0181 | 0.0101 | 0.0291 | 0.0194 | 0.0708 | 0.0738 | 0.0904 | 0.1042 | 0.0818 | 0.0821 | 0.1344 | 0.1245 | 0.5684 | 0.5784 | 0.0032 | 0.0051 | 0.0154 | 0.0199 | 0.0656 | 0.0836 | 0.0855 | 0.1215 | 0.6000 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 287 | 523 | | 301 | 5124 | 89.9 | 7.90 | 7.40 | 2.14 | 79 | 82 | 86 | 88 | 90 | 93 | 95 | 97 | 100 | 0.0720 | 369 | 0.946 | 37.36 | 10.77 | 0 | 0.3223 | 97 | 0.1482 | 0.45 | 2.153 | 0.7860 | 8141.3 | 742840 | 68300000 | 6310000000 | 0.3690 | 0.2667 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0066 | 0.0567 | 0.0532 | 0.0767 | 0.0831 | 0.0467 | 0.0432 | 0.0567 | 0.0565 | 0.7567 | 0.7575 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0120 | 0.0120 | 0.0542 | 0.0482 | 0.0783 | 0.1205 | 0.1084 | 0.5663 | 5 | 6 | 6 | 7 | 7 | 8 | 8 | 9 | 10 | 0.1708 | 0.51 | 1.021 | 0.4581 | 59.3 | 508.117 | 4604.6 | 43888.8 | 0.4666 | 0.2005 | 0.0058 | 0.0003 | 0.0341 | 0.0016 | 0.0942 | 0.0123 | 0.1790 | 0.0503 | 0.2344 | 0.1168 | 0.2308 | 0.1953 | 0.1477 | 0.2794 | 0.0651 | 0.2535 | 0.0090 | 0.0906 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0070 | 0.0015 | 0.0224 | 0.0088 | 0.0627 | 0.0354 | 0.1193 | 0.0626 | 0.1833 | 0.1375 | 0.3291 | 0.3390 | 0.2756 | 0.4152 | 0.0900 | 0.2589 | 0.1985 | 0.3018 | 0.2363 | 0.2417 | 0.2038 | 0.1227 | 0.1456 | 0.0577 | 0.0887 | 0.0135 | 0.0278 | 0.0025 | 0.0093 | 0.0012 | 0.0000 | 0.0000 | 0.0003 | 0.0097 | 0.0436 | 0.0951 | 0.1730 | 0.2360 | 0.2304 | 0.1642 | 0.0477 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 340 | 406 | | 471 | 6514 | 857.4 | 228.67 | 9.61 | 2.99 | 549 | 627 | 690 | 770 | 842 | 920 | 1002 | 1103 | 1189 | 0.0711 | 463 | 1.310 | 25.32 | 10.63 | 1 | 0.1423 | 67 | 0.0025 | 78.35 | 6.025 | 0.1012 | 787377.0 | 767000000 | 784000000000 | 832000000000000 | 0.3659 | 0.2545 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0099 | 0.0024 | 0.1034 | 0.0622 | 0.2512 | 0.0909 | 0.1281 | 0.0646 | 0.1823 | 0.0933 | 0.3251 | 0.6866 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0061 | 0.0022 | 0.0515 | 0.0500 | 0.0879 | 0.0609 | 0.0424 | 0.0391 | 0.0515 | 0.0543 | 0.7606 | 0.7935 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0079 | 0.0476 | 0.0787 | 0.1667 | 0.1496 | 0.1667 | 0.0315 | 0.0952 | 0.1260 | 0.1667 | 0.6063 | 0.3571 | 0.0000 | 0.0000 | 0.0000 | 0.0089 | 0.0536 | 0.1161 | 0.0402 | 0.0714 | 0.7098 | 6 | 7 | 8 | 9 | 9 | 10 | 11 | 12 | 13 | 0.0120 | 10.83 | 4.800 | 0.3191 | 101.2 | 1165.12 | 14657.4 | 201923 | 0.4760 | 0.1625 | 0.0062 | 0.0009 | 0.0309 | 0.0025 | 0.0752 | 0.0063 | 0.1498 | 0.0201 | 0.2096 | 0.0366 | 0.2372 | 0.0807 | 0.1938 | 0.1532 | 0.0783 | 0.3133 | 0.0190 | 0.3862 | 0.0016 | 0.0000 | 0.0096 | 0.0007 | 0.0200 | 0.0031 | 0.0446 | 0.0111 | 0.0824 | 0.0214 | 0.1177 | 0.0415 | 0.1815 | 0.0663 | 0.2235 | 0.1853 | 0.3192 | 0.6707 | 0.1143 | 0.2295 | 0.1414 | 0.1525 | 0.1455 | 0.1311 | 0.1299 | 0.0803 | 0.1225 | 0.0738 | 0.1049 | 0.0754 | 0.0683 | 0.0623 | 0.0751 | 0.1049 | 0.0981 | 0.0902 | 0.0313 | 0.0568 | 0.1064 | 0.1471 | 0.1279 | 0.1328 | 0.1432 | 0.1233 | 0.1312 |
| MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 791 | 738 | | 2836 | 2758 | 119.5 | 28.32 | 225.10 | 172.38 | 89 | 99 | 105 | 111 | 115 | 121 | 128 | 137 | 155 | 0.1653 | 456 | 0.603 | 236.69 | 51.26 | 1 | 0.2341 | 664 | 0.0036 | 15.13 | 5.972 | 0.2993 | 15085.0 | 2020000 | 291000000 | 45400000000 | 0.4422 | 0.2144 | 0.0000 | 0.0000 | 0.0005 | 0.0004 | 0.0021 | 0.0000 | 0.0185 | 0.0042 | 0.0723 | 0.0261 | 0.1083 | 0.0465 | 0.1591 | 0.0519 | 0.1657 | 0.0711 | 0.4736 | 0.7998 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0008 | 0.0000 | 0.0067 | 0.0011 | 0.0387 | 0.0176 | 0.0627 | 0.0269 | 0.0753 | 0.0298 | 0.0867 | 0.0384 | 0.7285 | 0.8863 | 0.0070 | 0.0054 | 0.0234 | 0.0163 | 0.0422 | 0.0217 | 0.0749 | 0.0761 | 0.1218 | 0.1848 | 0.1124 | 0.1902 | 0.1101 | 0.1196 | 0.1077 | 0.1413 | 0.4005 | 0.2446 | 0.0041 | 0.0033 | 0.0231 | 0.0430 | 0.1017 | 0.1479 | 0.1083 | 0.1380 | 0.4306 | 20 | 53 | 93 | 143 | 203 | 256 | 310 | 368 | 462 | 0.0047 | 47.42 | 6.617 | 0.2813 | 80370.2 | 35100000 | 17400000000 | 9480000000000 | 0.5310 | 0.1251 | 0.0062 | 0.0011 | 0.1040 | 0.0067 | 0.1996 | 0.0540 | 0.2100 | 0.1012 | 0.1580 | 0.1609 | 0.1393 | 0.2014 | 0.1123 | 0.1620 | 0.0499 | 0.1215 | 0.0208 | 0.1912 | 0.0000 | 0.0000 | 0.0007 | 0.0012 | 0.0033 | 0.0024 | 0.0127 | 0.0135 | 0.0560 | 0.0483 | 0.1133 | 0.0889 | 0.0833 | 0.0700 | 0.1227 | 0.0948 | 0.6080 | 0.6810 | 0.0000 | 0.0025 | 0.0010 | 0.0074 | 0.0059 | 0.0086 | 0.0285 | 0.0395 | 0.1050 | 0.1210 | 0.1501 | 0.1444 | 0.0991 | 0.1222 | 0.1511 | 0.1543 | 0.4593 | 0.4000 | 0.0008 | 0.0008 | 0.0032 | 0.0244 | 0.0630 | 0.1198 | 0.1072 | 0.1308 | 0.5500 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 409 | 280 | | 1210 | 12705 | 136.9 | 47.47 | 7.00 | 2.25 | 94 | 99 | 105 | 113 | 125 | 135 | 147 | 166 | 194 | 0.0692 | 879 | 1.125 | 43.57 | 14.76 | 1 | 0.0917 | 111 | 0.0334 | 1.77 | 3.937 | 0.6591 | 21001.6 | 3690000 | 750000000 | 175000000000 | 0.3856 | 0.2421 | 0.0019 | 0.0000 | 0.0038 | 0.0009 | 0.0076 | 0.0037 | 0.0284 | 0.0037 | 0.0739 | 0.0435 | 0.1155 | 0.0694 | 0.1098 | 0.0527 | 0.1553 | 0.0722 | 0.5038 | 0.7539 | 0.0000 | 0.0000 | 0.0026 | 0.0000 | 0.0039 | 0.0017 | 0.0116 | 0.0033 | 0.0374 | 0.0315 | 0.0452 | 0.0497 | 0.0477 | 0.0339 | 0.0671 | 0.0464 | 0.7845 | 0.8336 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0040 | 0.0157 | 0.0202 | 0.0315 | 0.0769 | 0.0945 | 0.1012 | 0.0945 | 0.0526 | 0.0945 | 0.1053 | 0.1102 | 0.6397 | 0.5591 | 0.0000 | 0.0021 | 0.0021 | 0.0170 | 0.0574 | 0.0894 | 0.0553 | 0.0830 | 0.6936 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 10 | 0.1326 | 0.46 | 0.972 | 0.3927 | 54.0 | 451.734 | 4043.45 | 38474.4 | 0.5298 | 0.1304 | 0.0062 | 0.0002 | 0.0387 | 0.0032 | 0.1097 | 0.0167 | 0.2018 | 0.0466 | 0.2471 | 0.1144 | 0.2141 | 0.2065 | 0.1330 | 0.2787 | 0.0443 | 0.2384 | 0.0050 | 0.0952 | 0.0003 | 0.0001 | 0.0037 | 0.0005 | 0.0155 | 0.0037 | 0.0453 | 0.0137 | 0.0937 | 0.0398 | 0.1649 | 0.1009 | 0.2199 | 0.1973 | 0.2501 | 0.3137 | 0.2066 | 0.3304 | 0.1155 | 0.2819 | 0.2058 | 0.2713 | 0.2077 | 0.1960 | 0.1816 | 0.1282 | 0.1344 | 0.0765 | 0.0859 | 0.0348 | 0.0478 | 0.0106 | 0.0186 | 0.0006 | 0.0028 | 0.0000 | 0.0087 | 0.0317 | 0.0841 | 0.1455 | 0.1982 | 0.2028 | 0.1646 | 0.1124 | 0.0521 |
| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 866 | 124 | | 7868 | 18298 | 509.3 | 103.27 | 71.24 | 63.85 | 380 | 418 | 450 | 475 | 502 | 530 | 561 | 596 | 645 | 0.0624 | 1141 | 1.024 | 98.60 | 36.00 | 1 | 0.0336 | 264 | 0.0007 | 43.87 | 7.460 | 0.1703 | 270039.0 | 149000000 | 85000000000 | 50300000000000 | 0.4294 | 0.2140 | 0.0004 | 0.0000 | 0.0011 | 0.0001 | 0.0029 | 0.0005 | 0.0116 | 0.0009 | 0.0506 | 0.0141 | 0.0958 | 0.0303 | 0.1076 | 0.0255 | 0.1326 | 0.0412 | 0.5975 | 0.8874 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0014 | 0.0001 | 0.0044 | 0.0005 | 0.0218 | 0.0097 | 0.0421 | 0.0212 | 0.0456 | 0.0141 | 0.0611 | 0.0214 | 0.8231 | 0.9329 | 0.0015 | 0.0151 | 0.0115 | 0.0075 | 0.0137 | 0.0491 | 0.0634 | 0.0943 | 0.0977 | 0.1698 | 0.1504 | 0.1698 | 0.1107 | 0.1132 | 0.1427 | 0.1208 | 0.4084 | 0.2604 | 0.0005 | 0.0021 | 0.0061 | 0.0192 | 0.0541 | 0.0908 | 0.0842 | 0.1111 | 0.6320 | 12 | 20 | 32 | 44 | 56 | 67 | 82 | 103 | 155 | 0.0160 | 5.43 | 4.946 | 0.5259 | 9151.3 | 1720000 | 410000000 | 113000000000 | 0.3977 | 0.2161 | 0.0063 | 0.0014 | 0.0287 | 0.0034 | 0.0848 | 0.0127 | 0.1175 | 0.0402 | 0.1734 | 0.0962 | 0.1759 | 0.1181 | 0.1582 | 0.1348 | 0.1455 | 0.1664 | 0.1097 | 0.4269 | 0.0011 | 0.0006 | 0.0036 | 0.0013 | 0.0059 | 0.0046 | 0.0190 | 0.0127 | 0.0462 | 0.0332 | 0.0641 | 0.0471 | 0.0697 | 0.0516 | 0.0984 | 0.0760 | 0.6920 | 0.7730 | 0.0018 | 0.0028 | 0.0049 | 0.0062 | 0.0101 | 0.0130 | 0.0352 | 0.0370 | 0.0677 | 0.0795 | 0.0948 | 0.0956 | 0.0883 | 0.0857 | 0.1176 | 0.1134 | 0.5795 | 0.5667 | 0.0029 | 0.0063 | 0.0092 | 0.0245 | 0.0550 | 0.0789 | 0.0782 | 0.1114 | 0.6337 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 145 | 220 | | 5756 | 11661 | 118.5 | 36.39 | 167.20 | 124.25 | 81 | 90 | 98 | 104 | 111 | 118 | 128 | 143 | 165 | 0.0846 | 986 | 0.856 | 102.96 | 27.00 | 1 | 0.0480 | 276 | 0.0023 | 23.04 | 6.430 | 0.2521 | 15367.1 | 2200000 | 352000000 | 62600000000 | 0.4200 | 0.2279 | 0.0020 | 0.0000 | 0.0029 | 0.0002 | 0.0150 | 0.0010 | 0.0444 | 0.0056 | 0.1120 | 0.0292 | 0.1639 | 0.0606 | 0.1681 | 0.0606 | 0.2099 | 0.0964 | 0.2818 | 0.7463 | 0.0014 | 0.0000 | 0.0009 | 0.0000 | 0.0050 | 0.0007 | 0.0159 | 0.0020 | 0.0515 | 0.0182 | 0.0735 | 0.0309 | 0.0871 | 0.0309 | 0.1288 | 0.0545 | 0.6358 | 0.8628 | 0.0043 | 0.0018 | 0.0130 | 0.0107 | 0.0260 | 0.0178 | 0.0582 | 0.0516 | 0.1094 | 0.1335 | 0.1432 | 0.2046 | 0.1102 | 0.1174 | 0.1363 | 0.1459 | 0.3993 | 0.3167 | 0.0030 | 0.0057 | 0.0174 | 0.0449 | 0.0858 | 0.1233 | 0.1054 | 0.1337 | 0.4808 | 25 | 50 | 81 | 110 | 144 | 177 | 218 | 274 | 343 | 0.0021 | 46.18 | 7.043 | 0.2601 | 43391.7 | 14100000 | 5330000000 | 2240000000000 | 0.5309 | 0.1392 | 0.0066 | 0.0007 | 0.0509 | 0.0066 | 0.1329 | 0.0201 | 0.1554 | 0.0531 | 0.1718 | 0.1357 | 0.1718 | 0.1713 | 0.1337 | 0.1501 | 0.1001 | 0.1692 | 0.0766 | 0.2933 | 0.0002 | 0.0003 | 0.0019 | 0.0009 | 0.0047 | 0.0031 | 0.0146 | 0.0122 | 0.0480 | 0.0427 | 0.0812 | 0.0603 | 0.0796 | 0.0606 | 0.1017 | 0.0883 | 0.6681 | 0.7316 | 0.0018 | 0.0022 | 0.0028 | 0.0073 | 0.0117 | 0.0105 | 0.0273 | 0.0350 | 0.0734 | 0.0815 | 0.1175 | 0.1238 | 0.0948 | 0.0986 | 0.1233 | 0.1371 | 0.5474 | 0.5040 | 0.0018 | 0.0034 | 0.0086 | 0.0243 | 0.0633 | 0.0955 | 0.0865 | 0.1196 | 0.5971 | ||
| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 283 | 97 | | 3964 | 10522 | 352.2 | 81.30 | 461.34 | 382.37 | 252 | 288 | 313 | 334 | 354 | 372 | 392 | 416 | 452 | 0.0657 | 691 | 0.753 | 95.27 | 24.08 | 1 | 0.0658 | 261 | 0.0006 | 102.74 | 7.612 | 0.1258 | 130633.0 | 50600000 | 20400000000 | 8530000000000 | 0.4023 | 0.2386 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0000 | 0.0179 | 0.0014 | 0.0550 | 0.0209 | 0.1072 | 0.0390 | 0.1228 | 0.0329 | 0.1454 | 0.0549 | 0.5458 | 0.8510 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0061 | 0.0013 | 0.0223 | 0.0154 | 0.0444 | 0.0260 | 0.0471 | 0.0172 | 0.0640 | 0.0262 | 0.8145 | 0.9139 | 0.0000 | 0.0109 | 0.0100 | 0.0109 | 0.0242 | 0.0217 | 0.0627 | 0.1033 | 0.1296 | 0.1467 | 0.1553 | 0.1413 | 0.1254 | 0.1196 | 0.1538 | 0.1033 | 0.3390 | 0.3424 | 0.0010 | 0.0035 | 0.0049 | 0.0233 | 0.0673 | 0.1054 | 0.1049 | 0.1242 | 0.5656 | 46 | 92 | 175 | 276 | 376 | 494 | 622 | 777 | 1000 | 0.0020 | 93.98 | 7.546 | 0.2428 | 359026.0 | 355000000 | 407000000000 | 521000000000000 | 0.5626 | 0.1363 | 0.0068 | 0.0015 | 0.0542 | 0.0057 | 0.1423 | 0.0121 | 0.1725 | 0.0508 | 0.1725 | 0.1309 | 0.1744 | 0.1967 | 0.1072 | 0.1517 | 0.0930 | 0.1565 | 0.0770 | 0.2940 | 0.0004 | 0.0000 | 0.0039 | 0.0011 | 0.0049 | 0.0030 | 0.0161 | 0.0105 | 0.0447 | 0.0377 | 0.0709 | 0.0692 | 0.0629 | 0.0510 | 0.0765 | 0.0729 | 0.7196 | 0.7546 | 0.0008 | 0.0007 | 0.0027 | 0.0023 | 0.0065 | 0.0073 | 0.0220 | 0.0293 | 0.0578 | 0.0676 | 0.0957 | 0.1119 | 0.0774 | 0.0916 | 0.1013 | 0.1196 | 0.6358 | 0.5696 | 0.0002 | 0.0022 | 0.0038 | 0.0146 | 0.0510 | 0.0864 | 0.0649 | 0.0858 | 0.6910 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 395 | 909 | | 589 | 5786 | 12.0 | 2.37 | 6.24 | 2.23 | 9 | 10 | 11 | 11 | 12 | 12 | 13 | 14 | 15 | 0.0990 | 573 | 0.731 | 73.43 | 17.00 | 0 | 0.3192 | 188 | 0.0185 | 6.32 | 4.289 | 0.3960 | 150.6 | 1953.66 | 26252.6 | 364792 | 0.3695 | 0.2656 | 0.0046 | 0.0000 | 0.0069 | 0.0018 | 0.0324 | 0.0036 | 0.0694 | 0.0164 | 0.1019 | 0.0455 | 0.1343 | 0.0764 | 0.1898 | 0.1218 | 0.1736 | 0.1818 | 0.2870 | 0.5527 | 0.0000 | 0.0000 | 0.0077 | 0.0000 | 0.0174 | 0.0017 | 0.0367 | 0.0156 | 0.0405 | 0.0363 | 0.0656 | 0.0554 | 0.1158 | 0.0606 | 0.1409 | 0.1125 | 0.5753 | 0.7180 | 0.0581 | 0.2857 | 0.0930 | 0.2500 | 0.1860 | 0.1071 | 0.1163 | 0.1786 | 0.1744 | 0.1071 | 0.1163 | 0.0714 | 0.0814 | 0.0000 | 0.1163 | 0.0000 | 0.0581 | 0.0000 | 0.0153 | 0.0337 | 0.0706 | 0.0982 | 0.1135 | 0.1350 | 0.1380 | 0.1503 | 0.2454 | 3 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0198 | 11.10 | 4.314 | 0.3248 | 43.9 | 336.777 | 2778.03 | 24382.5 | 0.5530 | 0.1191 | 0.0068 | 0.0000 | 0.0407 | 0.0041 | 0.1143 | 0.0182 | 0.2166 | 0.0597 | 0.2673 | 0.1261 | 0.2088 | 0.2311 | 0.1023 | 0.2725 | 0.0370 | 0.2133 | 0.0062 | 0.0750 | 0.0000 | 0.0000 | 0.0016 | 0.0006 | 0.0121 | 0.0032 | 0.0364 | 0.0132 | 0.0907 | 0.0355 | 0.1684 | 0.0778 | 0.2678 | 0.1906 | 0.2778 | 0.3647 | 0.1454 | 0.3144 | 0.1144 | 0.2816 | 0.2397 | 0.3609 | 0.2950 | 0.2346 | 0.1896 | 0.0927 | 0.1073 | 0.0268 | 0.0392 | 0.0034 | 0.0141 | 0.0000 | 0.0006 | 0.0000 | 0.0000 | 0.0000 | 0.0018 | 0.0090 | 0.0356 | 0.0844 | 0.1569 | 0.2511 | 0.2490 | 0.1644 | 0.0477 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 555 | 532 | | 3465 | 14759 | 319.8 | 107.54 | 6.73 | 2.27 | 198 | 221 | 243 | 273 | 310 | 350 | 374 | 394 | 435 | 0.0700 | 1033 | 1.221 | 77.39 | 27.66 | 2 | 0.0543 | 188 | 0.0057 | 5.18 | 5.576 | 0.4523 | 113808.0 | 45100000 | 19800000000 | 9650000000000 | 0.4430 | 0.1901 | 0.0028 | 0.0000 | 0.0063 | 0.0000 | 0.0042 | 0.0017 | 0.0245 | 0.0068 | 0.0756 | 0.0345 | 0.1436 | 0.0519 | 0.1289 | 0.0420 | 0.1646 | 0.0615 | 0.4496 | 0.8016 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0004 | 0.0012 | 0.0105 | 0.0031 | 0.0285 | 0.0271 | 0.0558 | 0.0389 | 0.0378 | 0.0249 | 0.0470 | 0.0408 | 0.8187 | 0.8639 | 0.0106 | 0.0000 | 0.0153 | 0.0071 | 0.0188 | 0.0035 | 0.0259 | 0.0390 | 0.0506 | 0.0887 | 0.0576 | 0.0957 | 0.0682 | 0.0780 | 0.0988 | 0.0993 | 0.6541 | 0.5887 | 0.0000 | 0.0024 | 0.0018 | 0.0152 | 0.0328 | 0.0425 | 0.0334 | 0.0468 | 0.8251 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0844 | 0.35 | 0.898 | 0.3300 | 50.5 | 413.246 | 3661.4 | 35082.4 | 0.5392 | 0.1292 | 0.0068 | 0.0003 | 0.0451 | 0.0042 | 0.1067 | 0.0171 | 0.1894 | 0.0476 | 0.2341 | 0.0957 | 0.2205 | 0.1698 | 0.1356 | 0.2507 | 0.0525 | 0.2678 | 0.0093 | 0.1466 | 0.0014 | 0.0002 | 0.0128 | 0.0021 | 0.0344 | 0.0077 | 0.0739 | 0.0219 | 0.1043 | 0.0520 | 0.1474 | 0.0981 | 0.1623 | 0.1436 | 0.2138 | 0.2421 | 0.2497 | 0.4324 | 0.1133 | 0.1976 | 0.1372 | 0.2142 | 0.1664 | 0.1783 | 0.1654 | 0.1636 | 0.1518 | 0.1123 | 0.1186 | 0.0744 | 0.0801 | 0.0372 | 0.0458 | 0.0160 | 0.0213 | 0.0064 | 0.0167 | 0.0531 | 0.0922 | 0.1109 | 0.1310 | 0.1500 | 0.1506 | 0.1588 | 0.1366 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 1039 | 381 | | 3800 | 9893 | 128.9 | 35.24 | 177.58 | 105.97 | 91 | 99 | 107 | 113 | 121 | 131 | 142 | 156 | 177 | 0.0668 | 661 | 1.078 | 92.18 | 30.89 | 1 | 0.0611 | 232 | 0.0025 | 19.96 | 6.337 | 0.2693 | 17862.2 | 2670000 | 431000000 | 74800000000 | 0.4064 | 0.2310 | 0.0020 | 0.0000 | 0.0049 | 0.0000 | 0.0133 | 0.0003 | 0.0405 | 0.0023 | 0.0968 | 0.0290 | 0.1532 | 0.0582 | 0.1502 | 0.0603 | 0.1789 | 0.0892 | 0.3602 | 0.7607 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0032 | 0.0000 | 0.0142 | 0.0011 | 0.0383 | 0.0165 | 0.0663 | 0.0315 | 0.0670 | 0.0221 | 0.1018 | 0.0464 | 0.7057 | 0.8824 | 0.0013 | 0.0000 | 0.0025 | 0.0150 | 0.0226 | 0.0240 | 0.0477 | 0.1201 | 0.1206 | 0.1592 | 0.1520 | 0.1742 | 0.1244 | 0.1171 | 0.1595 | 0.1411 | 0.3693 | 0.2492 | 0.0019 | 0.0038 | 0.0107 | 0.0239 | 0.0704 | 0.1157 | 0.0855 | 0.1157 | 0.5723 | 56 | 84 | 110 | 137 | 161 | 189 | 217 | 254 | 321 | 0.0018 | 32.40 | 6.743 | 0.2735 | 42762.9 | 12800000 | 4530000000 | 1830000000000 | 0.5224 | 0.1428 | 0.0069 | 0.0004 | 0.0360 | 0.0032 | 0.1033 | 0.0123 | 0.1645 | 0.0379 | 0.1920 | 0.0917 | 0.1882 | 0.1453 | 0.1446 | 0.1523 | 0.1037 | 0.1707 | 0.0608 | 0.3863 | 0.0007 | 0.0000 | 0.0011 | 0.0007 | 0.0051 | 0.0014 | 0.0161 | 0.0074 | 0.0562 | 0.0314 | 0.0904 | 0.0636 | 0.0907 | 0.0624 | 0.1212 | 0.0865 | 0.6186 | 0.7466 | 0.0019 | 0.0053 | 0.0061 | 0.0144 | 0.0200 | 0.0202 | 0.0517 | 0.0554 | 0.0950 | 0.1391 | 0.1363 | 0.1464 | 0.1266 | 0.1165 | 0.1315 | 0.1310 | 0.4309 | 0.3717 | 0.0011 | 0.0046 | 0.0090 | 0.0264 | 0.0790 | 0.1152 | 0.1061 | 0.1299 | 0.5287 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1173 | 230 | | 893 | 1587 | 58.0 | 13.43 | 491.67 | 350.26 | 39 | 45 | 50 | 54 | 59 | 63 | 67 | 71 | 75 | 0.1878 | 298 | 1.216 | 22.85 | 8.25 | 1 | 0.0694 | 62 | 0.0063 | 5.77 | 5.275 | 0.3973 | 3548.7 | 226676 | 15000000 | 1020000000 | 0.4245 | 0.2042 | 0.0041 | 0.0000 | 0.0104 | 0.0000 | 0.0228 | 0.0012 | 0.0352 | 0.0119 | 0.1056 | 0.0380 | 0.1201 | 0.0403 | 0.1677 | 0.0712 | 0.1822 | 0.0830 | 0.3520 | 0.7544 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0058 | 0.0012 | 0.0159 | 0.0116 | 0.0418 | 0.0359 | 0.0390 | 0.0348 | 0.0592 | 0.0475 | 0.0649 | 0.0487 | 0.7706 | 0.8204 | 0.0095 | 0.0500 | 0.0143 | 0.1000 | 0.0190 | 0.0500 | 0.0476 | 0.2000 | 0.1381 | 0.3000 | 0.1095 | 0.1000 | 0.1810 | 0.0000 | 0.1905 | 0.2000 | 0.2905 | 0.0000 | 0.0043 | 0.0151 | 0.0151 | 0.0129 | 0.0430 | 0.0688 | 0.0860 | 0.1011 | 0.6538 | 107 | 162 | 233 | 315 | 418 | 517 | 636 | 803 | 998 | 0.0021 | 39.34 | 6.548 | 0.2363 | 364349.0 | 335000000 | 350000000000 | 398000000000000 | 0.5161 | 0.1411 | 0.0070 | 0.0000 | 0.0702 | 0.0035 | 0.1579 | 0.0228 | 0.2316 | 0.0683 | 0.2140 | 0.1278 | 0.1789 | 0.2277 | 0.0877 | 0.1611 | 0.0386 | 0.1664 | 0.0140 | 0.2224 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0061 | 0.0020 | 0.0255 | 0.0201 | 0.0522 | 0.0413 | 0.0765 | 0.0554 | 0.0667 | 0.0564 | 0.1129 | 0.0816 | 0.6590 | 0.7432 | 0.0019 | 0.0000 | 0.0000 | 0.0047 | 0.0111 | 0.0213 | 0.0390 | 0.0332 | 0.0686 | 0.0900 | 0.1317 | 0.1232 | 0.0891 | 0.0853 | 0.1132 | 0.1422 | 0.5455 | 0.5000 | 0.0000 | 0.0059 | 0.0089 | 0.0341 | 0.0548 | 0.0904 | 0.0919 | 0.1407 | 0.5733 |