High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 603 | 882 | | 1319 | 7737 | 66.4 | 71.59 | 51.64 | 108.03 | 33 | 34 | 36 | 37 | 38 | 40 | 42 | 54 | 179 | 0.0778 | 602 | 1.235 | 41.48 | 16.64 | 4 | 0.0819 | 108 | 0.0362 | 35.18 | 4.239 | 0.5039 | 9528.0 | 2260000 | 632000000 | 189000000000 | 0.3313 | 0.2814 | 0.0000 | 0.0369 | 0.0984 | 0.0938 | 0.3770 | 0.0966 | 0.2295 | 0.0966 | 0.2623 | 0.0909 | 0.0328 | 0.1790 | 0.0000 | 0.1932 | 0.0000 | 0.1364 | 0.0000 | 0.0767 | 0.0000 | 0.0236 | 0.0036 | 0.0599 | 0.0036 | 0.0617 | 0.0073 | 0.0617 | 0.0584 | 0.0399 | 0.0730 | 0.0690 | 0.0474 | 0.0853 | 0.0766 | 0.0853 | 0.7299 | 0.5136 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0094 | 0.0101 | 0.0657 | 0.0653 | 0.0892 | 0.1005 | 0.0469 | 0.0503 | 0.0892 | 0.0804 | 0.6995 | 0.6935 | 0.0000 | 0.0000 | 0.0000 | 0.0170 | 0.0468 | 0.0979 | 0.0511 | 0.0638 | 0.7234 | 9 | 10 | 11 | 12 | 13 | 15 | 17 | 26 | 172 | 0.2813 | 8.15 | 2.652 | 0.7496 | 14334.9 | 6050000 | 2920000000 | 1530000000000 | 0.6889 | 0.0590 | 0.0938 | 0.0063 | 0.2313 | 0.0472 | 0.2375 | 0.1824 | 0.1813 | 0.1981 | 0.1000 | 0.2390 | 0.0938 | 0.1447 | 0.0250 | 0.0755 | 0.0313 | 0.0503 | 0.0063 | 0.0566 | 0.0000 | 0.0014 | 0.0008 | 0.0007 | 0.0031 | 0.0021 | 0.0178 | 0.0192 | 0.0666 | 0.0655 | 0.0860 | 0.0734 | 0.0713 | 0.0734 | 0.0953 | 0.0962 | 0.6592 | 0.6681 | 0.0000 | 0.0000 | 0.0009 | 0.0018 | 0.0035 | 0.0018 | 0.0221 | 0.0230 | 0.0716 | 0.0718 | 0.0902 | 0.0948 | 0.0875 | 0.0902 | 0.1043 | 0.0976 | 0.6198 | 0.6188 | 0.0008 | 0.0000 | 0.0017 | 0.0215 | 0.0710 | 0.0834 | 0.0859 | 0.0983 | 0.6375 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 125 | 887 | | 914 | 10249 | 57.4 | 40.69 | 232.85 | 304.99 | 28 | 31 | 33 | 35 | 38 | 42 | 56 | 82 | 127 | 0.0631 | 647 | 1.229 | 27.66 | 9.43 | 1 | 0.0722 | 66 | 0.0076 | 22.99 | 5.445 | 0.3165 | 4951.9 | 588247 | 83100000 | 12800000000 | 0.3258 | 0.3035 | 0.0088 | 0.0152 | 0.0000 | 0.0127 | 0.0531 | 0.0482 | 0.1239 | 0.0736 | 0.3451 | 0.1624 | 0.2832 | 0.1574 | 0.1416 | 0.1650 | 0.0354 | 0.1421 | 0.0088 | 0.2234 | 0.0000 | 0.0103 | 0.0000 | 0.0086 | 0.0091 | 0.0325 | 0.0151 | 0.0462 | 0.0393 | 0.0856 | 0.0665 | 0.0805 | 0.0665 | 0.0702 | 0.0634 | 0.0771 | 0.7402 | 0.5890 | 0.0000 | 0.0053 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0211 | 0.0826 | 0.0842 | 0.0872 | 0.0579 | 0.0459 | 0.0737 | 0.1101 | 0.0895 | 0.6697 | 0.6684 | 0.0000 | 0.0000 | 0.0037 | 0.0297 | 0.0409 | 0.0632 | 0.0743 | 0.0706 | 0.7175 | 22 | 26 | 32 | 50 | 83 | 141 | 256 | 424 | 686 | 0.0356 | 29.95 | 5.321 | 0.4926 | 147227.0 | 131000000 | 137000000000 | 161000000000000 | 0.6516 | 0.0660 | 0.0697 | 0.0026 | 0.1780 | 0.0222 | 0.2107 | 0.0941 | 0.1395 | 0.1359 | 0.1543 | 0.1737 | 0.1157 | 0.1966 | 0.0772 | 0.1261 | 0.0356 | 0.1261 | 0.0193 | 0.1228 | 0.0008 | 0.0002 | 0.0011 | 0.0012 | 0.0025 | 0.0051 | 0.0195 | 0.0177 | 0.0641 | 0.0572 | 0.0786 | 0.0824 | 0.0675 | 0.0545 | 0.0853 | 0.0863 | 0.6804 | 0.6953 | 0.0010 | 0.0015 | 0.0031 | 0.0035 | 0.0062 | 0.0073 | 0.0244 | 0.0289 | 0.0714 | 0.0763 | 0.0975 | 0.0960 | 0.0752 | 0.0867 | 0.0962 | 0.1044 | 0.6250 | 0.5954 | 0.0006 | 0.0012 | 0.0046 | 0.0178 | 0.0705 | 0.0911 | 0.0644 | 0.0929 | 0.6569 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1103 | 521 | | 38572 | 41531 | 83.7 | 70.09 | 7.10 | 2.74 | 45 | 48 | 50 | 53 | 56 | 62 | 73 | 98 | 152 | 0.0457 | 1898 | 0.782 | 128.16 | 45.34 | 3 | 0.0101 | 390 | 0.0492 | 1.50 | 4.084 | 0.6882 | 11919.8 | 2870000 | 920000000 | 334000000000 | 0.4510 | 0.1895 | 0.0109 | 0.0089 | 0.0164 | 0.0172 | 0.0246 | 0.0246 | 0.0351 | 0.0389 | 0.0605 | 0.0504 | 0.0801 | 0.0590 | 0.0958 | 0.0673 | 0.1409 | 0.0885 | 0.5357 | 0.6452 | 0.0040 | 0.0067 | 0.0055 | 0.0130 | 0.0089 | 0.0188 | 0.0105 | 0.0286 | 0.0183 | 0.0354 | 0.0237 | 0.0412 | 0.0271 | 0.0468 | 0.0418 | 0.0594 | 0.8604 | 0.7500 | 0.0015 | 0.0009 | 0.0027 | 0.0019 | 0.0047 | 0.0041 | 0.0104 | 0.0090 | 0.0173 | 0.0159 | 0.0259 | 0.0282 | 0.0314 | 0.0309 | 0.0401 | 0.0398 | 0.8660 | 0.8695 | 0.0020 | 0.0024 | 0.0056 | 0.0088 | 0.0174 | 0.0214 | 0.0294 | 0.0366 | 0.8764 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 9 | 11 | 0.4747 | 0.33 | 1.180 | 0.8414 | 57.9 | 527.37 | 5295.83 | 58155.7 | 0.4995 | 0.1829 | 0.0184 | 0.0024 | 0.0723 | 0.0096 | 0.1551 | 0.0301 | 0.2242 | 0.0749 | 0.2394 | 0.1555 | 0.1742 | 0.2423 | 0.0889 | 0.2556 | 0.0251 | 0.1713 | 0.0024 | 0.0583 | 0.0022 | 0.0001 | 0.0106 | 0.0010 | 0.0291 | 0.0053 | 0.0623 | 0.0178 | 0.1060 | 0.0556 | 0.1606 | 0.1162 | 0.2066 | 0.1940 | 0.2316 | 0.2914 | 0.1910 | 0.3187 | 0.0905 | 0.1632 | 0.1612 | 0.2060 | 0.1796 | 0.1882 | 0.1754 | 0.1469 | 0.1412 | 0.1102 | 0.1007 | 0.0685 | 0.0624 | 0.0461 | 0.0489 | 0.0412 | 0.0401 | 0.0296 | 0.0110 | 0.0392 | 0.0830 | 0.1233 | 0.1517 | 0.1724 | 0.1677 | 0.1502 | 0.1015 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 524 | 311 | | 7833 | 16316 | 159.4 | 129.05 | 84.65 | 174.06 | 65 | 76 | 86 | 97 | 114 | 131 | 150 | 185 | 382 | 0.0834 | 1360 | 1.188 | 60.96 | 23.71 | 5 | 0.0200 | 157 | 0.0057 | 7.18 | 5.903 | 0.4831 | 42052.4 | 16100000 | 7440000000 | 3750000000000 | 0.4134 | 0.2024 | 0.0022 | 0.0044 | 0.0039 | 0.0032 | 0.0061 | 0.0041 | 0.0335 | 0.0116 | 0.0754 | 0.0367 | 0.0972 | 0.0576 | 0.0972 | 0.0547 | 0.1056 | 0.0789 | 0.5788 | 0.7488 | 0.0012 | 0.0031 | 0.0021 | 0.0023 | 0.0027 | 0.0029 | 0.0140 | 0.0079 | 0.0273 | 0.0211 | 0.0334 | 0.0280 | 0.0404 | 0.0320 | 0.0507 | 0.0445 | 0.8282 | 0.8580 | 0.0007 | 0.0000 | 0.0007 | 0.0000 | 0.0033 | 0.0000 | 0.0086 | 0.0022 | 0.0213 | 0.0230 | 0.0452 | 0.0445 | 0.0219 | 0.0208 | 0.0359 | 0.0408 | 0.8625 | 0.8687 | 0.0005 | 0.0039 | 0.0043 | 0.0096 | 0.0294 | 0.0487 | 0.0352 | 0.0545 | 0.8140 | 8 | 10 | 12 | 15 | 18 | 24 | 39 | 87 | 242 | 0.1992 | 8.64 | 2.988 | 0.7068 | 37461.6 | 26400000 | 22100000000 | 20600000000000 | 0.5330 | 0.1352 | 0.0090 | 0.0029 | 0.0336 | 0.0070 | 0.0493 | 0.0187 | 0.1087 | 0.0531 | 0.1659 | 0.0904 | 0.1839 | 0.1376 | 0.1390 | 0.1405 | 0.1312 | 0.1359 | 0.1794 | 0.4140 | 0.0005 | 0.0009 | 0.0029 | 0.0023 | 0.0029 | 0.0042 | 0.0098 | 0.0168 | 0.0383 | 0.0349 | 0.0554 | 0.0519 | 0.0449 | 0.0496 | 0.0660 | 0.0575 | 0.7794 | 0.7817 | 0.0021 | 0.0004 | 0.0017 | 0.0035 | 0.0045 | 0.0047 | 0.0141 | 0.0116 | 0.0497 | 0.0520 | 0.0783 | 0.0849 | 0.0583 | 0.0621 | 0.0852 | 0.0791 | 0.7060 | 0.7017 | 0.0009 | 0.0033 | 0.0045 | 0.0117 | 0.0415 | 0.0667 | 0.0505 | 0.0739 | 0.7471 |
| MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1201 | 147 | | 25401 | 21792 | 80.3 | 36.47 | 7.79 | 3.16 | 47 | 51 | 55 | 60 | 67 | 79 | 95 | 111 | 130 | 0.0646 | 1407 | 0.643 | 109.48 | 22.02 | 3 | 0.0122 | 311 | 0.0238 | 1.54 | 4.339 | 0.6433 | 7784.7 | 930349 | 141000000 | 27400000000 | 0.3746 | 0.2574 | 0.0183 | 0.0041 | 0.0285 | 0.0101 | 0.0332 | 0.0165 | 0.0445 | 0.0216 | 0.0579 | 0.0307 | 0.0760 | 0.0454 | 0.0991 | 0.0645 | 0.1547 | 0.1011 | 0.4878 | 0.7059 | 0.0063 | 0.0025 | 0.0088 | 0.0051 | 0.0101 | 0.0093 | 0.0128 | 0.0127 | 0.0158 | 0.0171 | 0.0202 | 0.0254 | 0.0263 | 0.0353 | 0.0450 | 0.0545 | 0.8547 | 0.8381 | 0.0029 | 0.0096 | 0.0051 | 0.0076 | 0.0087 | 0.0135 | 0.0154 | 0.0237 | 0.0181 | 0.0317 | 0.0252 | 0.0416 | 0.0356 | 0.0590 | 0.0614 | 0.0833 | 0.8277 | 0.7300 | 0.0039 | 0.0045 | 0.0066 | 0.0106 | 0.0121 | 0.0194 | 0.0250 | 0.0402 | 0.8777 | 4 | 5 | 6 | 7 | 8 | 9 | 9 | 10 | 12 | 0.3288 | 0.54 | 1.489 | 0.7679 | 70.7 | 710.738 | 7758.34 | 90867.1 | 0.5651 | 0.1468 | 0.0276 | 0.0002 | 0.1012 | 0.0027 | 0.1830 | 0.0162 | 0.2395 | 0.0448 | 0.2232 | 0.1065 | 0.1440 | 0.1983 | 0.0622 | 0.2724 | 0.0175 | 0.2494 | 0.0018 | 0.1095 | 0.0011 | 0.0001 | 0.0095 | 0.0007 | 0.0313 | 0.0047 | 0.0743 | 0.0148 | 0.1392 | 0.0405 | 0.2209 | 0.1002 | 0.2544 | 0.1989 | 0.1985 | 0.3291 | 0.0707 | 0.3109 | 0.0837 | 0.3817 | 0.2220 | 0.3524 | 0.2715 | 0.1695 | 0.2102 | 0.0699 | 0.1317 | 0.0232 | 0.0547 | 0.0028 | 0.0218 | 0.0004 | 0.0035 | 0.0000 | 0.0010 | 0.0000 | 0.0061 | 0.0422 | 0.1149 | 0.1974 | 0.2403 | 0.2128 | 0.1308 | 0.0484 | 0.0072 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 372 | 139 | | 4417 | 11190 | 35.9 | 14.42 | 6.81 | 2.68 | 18 | 23 | 27 | 31 | 35 | 38 | 42 | 47 | 55 | 0.1108 | 1240 | 0.972 | 96.52 | 27.73 | 0 | 0.0541 | 239 | 0.0016 | 19.80 | 6.657 | 0.2399 | 1496.0 | 70708.7 | 3720000 | 215000000 | 0.3566 | 0.2612 | 0.0074 | 0.0033 | 0.0138 | 0.0046 | 0.0275 | 0.0100 | 0.0401 | 0.0219 | 0.0682 | 0.0306 | 0.1181 | 0.0604 | 0.1456 | 0.0764 | 0.2189 | 0.1249 | 0.3605 | 0.6679 | 0.0027 | 0.0016 | 0.0044 | 0.0025 | 0.0061 | 0.0041 | 0.0123 | 0.0106 | 0.0194 | 0.0144 | 0.0310 | 0.0289 | 0.0358 | 0.0324 | 0.0607 | 0.0501 | 0.8275 | 0.8554 | 0.0135 | 0.0136 | 0.0143 | 0.0303 | 0.0236 | 0.0394 | 0.0412 | 0.0455 | 0.0648 | 0.0636 | 0.0732 | 0.0924 | 0.0875 | 0.1030 | 0.1052 | 0.1288 | 0.5766 | 0.4833 | 0.0024 | 0.0118 | 0.0142 | 0.0217 | 0.0307 | 0.0558 | 0.0728 | 0.1281 | 0.6626 | 3 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0130 | 14.88 | 4.690 | 0.2835 | 53.5 | 466.389 | 4418.91 | 44994.1 | 0.5386 | 0.1220 | 0.0193 | 0.0018 | 0.0771 | 0.0147 | 0.1782 | 0.0531 | 0.2352 | 0.1151 | 0.2415 | 0.1932 | 0.1553 | 0.2539 | 0.0676 | 0.2164 | 0.0219 | 0.1202 | 0.0039 | 0.0316 | 0.0009 | 0.0001 | 0.0099 | 0.0021 | 0.0376 | 0.0123 | 0.0944 | 0.0380 | 0.1707 | 0.0873 | 0.2304 | 0.1689 | 0.2167 | 0.2533 | 0.1681 | 0.2793 | 0.0711 | 0.1586 | 0.1499 | 0.2801 | 0.2687 | 0.3198 | 0.2320 | 0.2121 | 0.1617 | 0.1088 | 0.0909 | 0.0480 | 0.0568 | 0.0201 | 0.0279 | 0.0084 | 0.0099 | 0.0022 | 0.0022 | 0.0006 | 0.0072 | 0.0437 | 0.1150 | 0.1799 | 0.2208 | 0.1990 | 0.1331 | 0.0731 | 0.0283 |
| Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 862 | 60 | | 536 | 8372 | 94.9 | 38.62 | 150.81 | 294.15 | 38 | 55 | 70 | 85 | 97 | 109 | 121 | 135 | 146 | 0.0688 | 576 | 0.456 | 105.65 | 21.93 | 2 | 0.7705 | 413 | 0.0025 | 45.30 | 6.078 | 0.1747 | 10500.4 | 1270000 | 163000000 | 21700000000 | 0.3490 | 0.2577 | 0.0000 | 0.0032 | 0.0057 | 0.0000 | 0.0345 | 0.0000 | 0.1149 | 0.0097 | 0.1782 | 0.0968 | 0.1782 | 0.1452 | 0.1322 | 0.1161 | 0.1379 | 0.1613 | 0.2184 | 0.4677 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0137 | 0.0024 | 0.0521 | 0.0471 | 0.0493 | 0.0659 | 0.0548 | 0.0329 | 0.0740 | 0.0776 | 0.7562 | 0.7741 | 0.0000 | 0.0000 | 0.0052 | 0.0000 | 0.0052 | 0.0087 | 0.0209 | 0.0435 | 0.0995 | 0.1130 | 0.0785 | 0.1130 | 0.1099 | 0.1217 | 0.1152 | 0.1739 | 0.5654 | 0.4261 | 0.0000 | 0.0000 | 0.0035 | 0.0142 | 0.0745 | 0.0816 | 0.0780 | 0.0957 | 0.6525 | 15 | 18 | 20 | 22 | 25 | 32 | 64 | 197 | 482 | 0.1543 | 30.36 | 3.816 | 0.6306 | 109258.0 | 124000000 | 171000000000 | 266000000000000 | 0.6017 | 0.0867 | 0.1678 | 0.0032 | 0.3557 | 0.0852 | 0.2550 | 0.2981 | 0.1040 | 0.2618 | 0.0570 | 0.1467 | 0.0336 | 0.1073 | 0.0201 | 0.0442 | 0.0067 | 0.0331 | 0.0000 | 0.0205 | 0.0010 | 0.0004 | 0.0025 | 0.0018 | 0.0029 | 0.0031 | 0.0152 | 0.0161 | 0.0678 | 0.0629 | 0.1130 | 0.0915 | 0.0683 | 0.0683 | 0.1170 | 0.1071 | 0.6123 | 0.6488 | 0.0006 | 0.0006 | 0.0012 | 0.0006 | 0.0069 | 0.0056 | 0.0242 | 0.0311 | 0.0806 | 0.0840 | 0.1163 | 0.1319 | 0.0996 | 0.0989 | 0.1232 | 0.1319 | 0.5475 | 0.5152 | 0.0011 | 0.0021 | 0.0037 | 0.0144 | 0.0880 | 0.1077 | 0.0859 | 0.1189 | 0.5781 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1133 | 155 | | 893 | 1399 | 15.3 | 5.59 | 6.05 | 2.57 | 9 | 11 | 12 | 13 | 14 | 15 | 17 | 19 | 23 | 0.2437 | 341 | 0.631 | 86.21 | 19.03 | 0 | 0.2520 | 225 | 0.0063 | 15.00 | 5.353 | 0.2862 | 266.3 | 5252.12 | 117067 | 2910000 | 0.3793 | 0.2519 | 0.0048 | 0.0028 | 0.0333 | 0.0000 | 0.0643 | 0.0127 | 0.1452 | 0.0325 | 0.1786 | 0.0734 | 0.2262 | 0.0805 | 0.1762 | 0.1427 | 0.1143 | 0.2260 | 0.0571 | 0.4294 | 0.0000 | 0.0000 | 0.0120 | 0.0000 | 0.0240 | 0.0059 | 0.0314 | 0.0202 | 0.0569 | 0.0308 | 0.0883 | 0.0403 | 0.1033 | 0.0664 | 0.1856 | 0.1151 | 0.4985 | 0.7212 | 0.0282 | 0.0444 | 0.0726 | 0.0667 | 0.0565 | 0.0963 | 0.0645 | 0.1037 | 0.1089 | 0.0889 | 0.1089 | 0.0963 | 0.1089 | 0.1185 | 0.1573 | 0.1481 | 0.2944 | 0.2370 | 0.0070 | 0.0282 | 0.0446 | 0.0845 | 0.1009 | 0.1056 | 0.1502 | 0.1291 | 0.3498 | 2 | 4 | 4 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0207 | 14.14 | 4.219 | 0.3005 | 43.2 | 342.525 | 2947.43 | 27112.9 | 0.5136 | 0.1528 | 0.0287 | 0.0010 | 0.1396 | 0.0117 | 0.2199 | 0.0321 | 0.2581 | 0.0884 | 0.1893 | 0.1574 | 0.1090 | 0.2235 | 0.0402 | 0.2673 | 0.0134 | 0.1720 | 0.0019 | 0.0466 | 0.0022 | 0.0000 | 0.0151 | 0.0048 | 0.0635 | 0.0032 | 0.1389 | 0.0415 | 0.2099 | 0.0909 | 0.2196 | 0.1085 | 0.2056 | 0.1699 | 0.1044 | 0.2759 | 0.0409 | 0.3054 | 0.1010 | 0.3289 | 0.2241 | 0.3156 | 0.1946 | 0.2089 | 0.1749 | 0.0800 | 0.1626 | 0.0444 | 0.0788 | 0.0222 | 0.0542 | 0.0000 | 0.0099 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0320 | 0.0959 | 0.1337 | 0.2024 | 0.2237 | 0.1787 | 0.0959 | 0.0296 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 695 | 131 | | 413 | 5107 | 82.1 | 20.31 | 279.73 | 253.72 | 58 | 64 | 69 | 74 | 79 | 84 | 91 | 98 | 113 | 0.0832 | 425 | 0.434 | 131.03 | 25.55 | 1 | 1.0266 | 424 | 0.0060 | 18.02 | 5.295 | 0.2565 | 7150.1 | 660661 | 64600000 | 6650000000 | 0.4371 | 0.1916 | 0.0042 | 0.0027 | 0.0042 | 0.0000 | 0.0333 | 0.0027 | 0.0667 | 0.0239 | 0.2042 | 0.0557 | 0.1708 | 0.1326 | 0.1708 | 0.0849 | 0.1667 | 0.1618 | 0.1792 | 0.5358 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0219 | 0.0121 | 0.0909 | 0.0388 | 0.1285 | 0.1068 | 0.1003 | 0.0485 | 0.1317 | 0.0801 | 0.5235 | 0.7136 | 0.0127 | 0.0000 | 0.0506 | 0.0571 | 0.0253 | 0.0286 | 0.1266 | 0.3143 | 0.2025 | 0.1429 | 0.1772 | 0.2571 | 0.1392 | 0.2000 | 0.1266 | 0.0000 | 0.1392 | 0.0000 | 0.0000 | 0.0000 | 0.0108 | 0.0914 | 0.1452 | 0.1935 | 0.1774 | 0.1452 | 0.2366 | 25 | 49 | 96 | 153 | 212 | 275 | 354 | 477 | 655 | 0.0063 | 78.62 | 6.665 | 0.3190 | 142608.0 | 95700000 | 75600000000 | 66600000000000 | 0.5065 | 0.1700 | 0.0221 | 0.0019 | 0.0858 | 0.0044 | 0.1495 | 0.0386 | 0.1507 | 0.0880 | 0.1667 | 0.1381 | 0.1507 | 0.1837 | 0.1164 | 0.1343 | 0.0931 | 0.1279 | 0.0650 | 0.2831 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0045 | 0.0010 | 0.0179 | 0.0102 | 0.0595 | 0.0459 | 0.0965 | 0.0856 | 0.0892 | 0.0652 | 0.1071 | 0.0883 | 0.6244 | 0.7037 | 0.0018 | 0.0007 | 0.0031 | 0.0044 | 0.0067 | 0.0095 | 0.0329 | 0.0352 | 0.0940 | 0.1232 | 0.1416 | 0.1576 | 0.1159 | 0.1188 | 0.1495 | 0.1503 | 0.4545 | 0.4003 | 0.0010 | 0.0015 | 0.0050 | 0.0223 | 0.0819 | 0.1166 | 0.1052 | 0.1454 | 0.5211 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 785 | 881 | | 3192 | 11680 | 293.5 | 228.83 | 175.43 | 253.66 | 121 | 132 | 141 | 152 | 168 | 234 | 343 | 454 | 665 | 0.0779 | 910 | 0.548 | 96.01 | 23.41 | 1 | 0.0883 | 282 | 0.0123 | 12.19 | 5.534 | 0.4708 | 138508.0 | 89800000 | 68800000000 | 57800000000000 | 0.3485 | 0.2740 | 0.0000 | 0.0026 | 0.0088 | 0.0040 | 0.0234 | 0.0026 | 0.0848 | 0.0145 | 0.2193 | 0.0818 | 0.2339 | 0.1385 | 0.0994 | 0.0989 | 0.1053 | 0.1280 | 0.2251 | 0.5290 | 0.0000 | 0.0013 | 0.0000 | 0.0020 | 0.0000 | 0.0013 | 0.0039 | 0.0040 | 0.0308 | 0.0246 | 0.0394 | 0.0378 | 0.0308 | 0.0252 | 0.0450 | 0.0358 | 0.8502 | 0.8680 | 0.0011 | 0.0000 | 0.0000 | 0.0000 | 0.0022 | 0.0013 | 0.0043 | 0.0053 | 0.0335 | 0.0427 | 0.0475 | 0.0521 | 0.0367 | 0.0427 | 0.0583 | 0.0681 | 0.8164 | 0.7877 | 0.0000 | 0.0000 | 0.0000 | 0.0046 | 0.0316 | 0.0418 | 0.0316 | 0.0501 | 0.8403 | 8 | 11 | 13 | 16 | 30 | 86 | 182 | 350 | 586 | 0.1317 | 8.32 | 4.290 | 0.5950 | 95114.7 | 66900000 | 53100000000 | 45800000000000 | 0.4601 | 0.1966 | 0.0174 | 0.0027 | 0.1172 | 0.0096 | 0.2084 | 0.0541 | 0.1852 | 0.1021 | 0.1881 | 0.1568 | 0.1389 | 0.1637 | 0.0767 | 0.1301 | 0.0449 | 0.1548 | 0.0232 | 0.2260 | 0.0003 | 0.0000 | 0.0003 | 0.0005 | 0.0025 | 0.0018 | 0.0104 | 0.0100 | 0.0440 | 0.0382 | 0.0552 | 0.0567 | 0.0575 | 0.0473 | 0.0699 | 0.0678 | 0.7600 | 0.7777 | 0.0000 | 0.0007 | 0.0022 | 0.0027 | 0.0040 | 0.0065 | 0.0160 | 0.0143 | 0.0413 | 0.0419 | 0.0703 | 0.0671 | 0.0518 | 0.0504 | 0.0679 | 0.0740 | 0.7465 | 0.7423 | 0.0000 | 0.0020 | 0.0031 | 0.0134 | 0.0431 | 0.0641 | 0.0532 | 0.0661 | 0.7549 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 953 | 241 | | 4452 | 16651 | 514.3 | 202.79 | 16.75 | 22.48 | 264 | 314 | 365 | 425 | 496 | 574 | 650 | 721 | 776 | 0.0610 | 1016 | 0.831 | 150.81 | 30.46 | 9 | 0.0806 | 359 | 0.0007 | 46.67 | 7.524 | 0.1977 | 305620.0 | 203000000 | 146000000000 | 112000000000000 | 0.3891 | 0.2375 | 0.0008 | 0.0022 | 0.0000 | 0.0000 | 0.0142 | 0.0022 | 0.0334 | 0.0103 | 0.0943 | 0.0357 | 0.1060 | 0.0600 | 0.1018 | 0.0527 | 0.1277 | 0.0681 | 0.5217 | 0.7688 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0015 | 0.0003 | 0.0036 | 0.0052 | 0.0259 | 0.0196 | 0.0353 | 0.0304 | 0.0230 | 0.0232 | 0.0383 | 0.0312 | 0.8724 | 0.8898 | 0.0000 | 0.0000 | 0.0000 | 0.0044 | 0.0019 | 0.0044 | 0.0045 | 0.0166 | 0.0408 | 0.0376 | 0.0388 | 0.0564 | 0.0323 | 0.0431 | 0.0511 | 0.0818 | 0.8305 | 0.7558 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0262 | 0.0419 | 0.0295 | 0.0409 | 0.8548 | 6 | 7 | 8 | 9 | 11 | 14 | 17 | 22 | 30 | 0.1712 | 0.40 | 1.575 | 0.6158 | 785.9 | 143855 | 50100000 | 21000000000 | 0.6171 | 0.0868 | 0.0605 | 0.0488 | 0.0678 | 0.0590 | 0.0946 | 0.0585 | 0.1398 | 0.0738 | 0.1565 | 0.0814 | 0.1773 | 0.0904 | 0.1603 | 0.1323 | 0.1067 | 0.1903 | 0.0365 | 0.2655 | 0.0178 | 0.0287 | 0.0157 | 0.0319 | 0.0185 | 0.0277 | 0.0267 | 0.0319 | 0.0491 | 0.0406 | 0.0697 | 0.0463 | 0.0717 | 0.0582 | 0.1168 | 0.0921 | 0.6140 | 0.6425 | 0.0160 | 0.0168 | 0.0214 | 0.0291 | 0.0295 | 0.0412 | 0.0447 | 0.0496 | 0.0736 | 0.0814 | 0.0894 | 0.0941 | 0.1054 | 0.1129 | 0.1416 | 0.1313 | 0.4783 | 0.4436 | 0.0152 | 0.0164 | 0.0269 | 0.0290 | 0.0574 | 0.0696 | 0.0884 | 0.1384 | 0.5589 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 632 | 365 | | 4889 | 13256 | 383.0 | 256.14 | 34.30 | 57.66 | 183 | 197 | 211 | 228 | 257 | 316 | 420 | 590 | 842 | 0.0671 | 890 | 0.504 | 95.59 | 26.87 | 10 | 0.0714 | 349 | 0.0027 | 26.56 | 6.768 | 0.3301 | 212277.0 | 153000000 | 126000000000 | 111000000000000 | 0.4295 | 0.1988 | 0.0014 | 0.0022 | 0.0000 | 0.0011 | 0.0177 | 0.0092 | 0.0477 | 0.0152 | 0.1376 | 0.0656 | 0.2030 | 0.1062 | 0.1444 | 0.0846 | 0.1253 | 0.1084 | 0.3229 | 0.6076 | 0.0000 | 0.0014 | 0.0000 | 0.0007 | 0.0010 | 0.0058 | 0.0030 | 0.0093 | 0.0272 | 0.0319 | 0.0495 | 0.0436 | 0.0302 | 0.0367 | 0.0475 | 0.0480 | 0.8417 | 0.8226 | 0.0000 | 0.0019 | 0.0000 | 0.0000 | 0.0039 | 0.0000 | 0.0070 | 0.0056 | 0.0396 | 0.0318 | 0.0591 | 0.0589 | 0.0311 | 0.0308 | 0.0521 | 0.0421 | 0.8073 | 0.8290 | 0.0000 | 0.0000 | 0.0000 | 0.0055 | 0.0325 | 0.0644 | 0.0319 | 0.0576 | 0.8081 | 6 | 7 | 9 | 11 | 13 | 17 | 25 | 40 | 85 | 0.1143 | 7.18 | 3.518 | 0.6992 | 4501.5 | 1130000 | 367000000 | 138000000000 | 0.5010 | 0.1794 | 0.0284 | 0.0102 | 0.0869 | 0.0191 | 0.1446 | 0.0339 | 0.1683 | 0.0750 | 0.1629 | 0.1280 | 0.1299 | 0.1522 | 0.1034 | 0.1314 | 0.1052 | 0.1526 | 0.0704 | 0.2976 | 0.0040 | 0.0039 | 0.0059 | 0.0071 | 0.0075 | 0.0092 | 0.0215 | 0.0184 | 0.0557 | 0.0417 | 0.0796 | 0.0708 | 0.0632 | 0.0565 | 0.0866 | 0.0877 | 0.6759 | 0.7047 | 0.0019 | 0.0022 | 0.0019 | 0.0013 | 0.0095 | 0.0056 | 0.0175 | 0.0233 | 0.0712 | 0.0739 | 0.1086 | 0.1188 | 0.0712 | 0.0774 | 0.1036 | 0.1059 | 0.6145 | 0.5916 | 0.0032 | 0.0064 | 0.0051 | 0.0185 | 0.0543 | 0.1006 | 0.0716 | 0.1016 | 0.6387 |
| SK-BR-3 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 770 | 194 | | 4106 | 14842 | 217.4 | 110.14 | 102.63 | 168.85 | 87 | 104 | 124 | 149 | 193 | 255 | 309 | 338 | 368 | 0.0595 | 883 | 0.734 | 130.10 | 25.02 | 4 | 0.0774 | 318 | 0.0016 | 20.13 | 6.862 | 0.2708 | 59394.7 | 18600000 | 6250000000 | 2190000000000 | 0.3003 | 0.3143 | 0.0017 | 0.0020 | 0.0017 | 0.0047 | 0.0050 | 0.0027 | 0.0199 | 0.0182 | 0.1393 | 0.0532 | 0.2703 | 0.1097 | 0.1294 | 0.0787 | 0.1592 | 0.1016 | 0.2736 | 0.6292 | 0.0000 | 0.0004 | 0.0000 | 0.0011 | 0.0005 | 0.0007 | 0.0014 | 0.0043 | 0.0199 | 0.0180 | 0.0398 | 0.0371 | 0.0172 | 0.0213 | 0.0330 | 0.0317 | 0.8883 | 0.8853 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0019 | 0.0023 | 0.0025 | 0.0070 | 0.0243 | 0.0319 | 0.0473 | 0.0474 | 0.0230 | 0.0365 | 0.0398 | 0.0629 | 0.8613 | 0.8096 | 0.0000 | 0.0000 | 0.0010 | 0.0047 | 0.0210 | 0.0367 | 0.0257 | 0.0352 | 0.8756 | 12 | 15 | 18 | 23 | 35 | 53 | 82 | 137 | 279 | 0.0621 | 16.73 | 4.450 | 0.6158 | 39039.8 | 25800000 | 21500000000 | 20400000000000 | 0.5806 | 0.1178 | 0.0142 | 0.0012 | 0.0745 | 0.0050 | 0.1347 | 0.0255 | 0.1665 | 0.0751 | 0.1808 | 0.1211 | 0.1548 | 0.1645 | 0.1163 | 0.1413 | 0.0879 | 0.1463 | 0.0703 | 0.3200 | 0.0004 | 0.0002 | 0.0022 | 0.0006 | 0.0034 | 0.0017 | 0.0117 | 0.0140 | 0.0549 | 0.0436 | 0.0904 | 0.0624 | 0.0616 | 0.0618 | 0.0940 | 0.0822 | 0.6814 | 0.7336 | 0.0000 | 0.0000 | 0.0015 | 0.0028 | 0.0065 | 0.0070 | 0.0175 | 0.0228 | 0.0713 | 0.0831 | 0.1208 | 0.1189 | 0.0799 | 0.0856 | 0.1097 | 0.1140 | 0.5927 | 0.5658 | 0.0008 | 0.0024 | 0.0040 | 0.0129 | 0.0630 | 0.1018 | 0.0691 | 0.1036 | 0.6424 |
| Hs 578T | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 653 | 516 | | 909 | 892 | 22.8 | 11.51 | 5.20 | 1.87 | 10 | 12 | 15 | 18 | 21 | 23 | 27 | 31 | 38 | 0.3509 | 313 | 1.192 | 32.02 | 13.34 | 0 | 0.0957 | 87 | 0.0035 | 17.77 | 5.844 | 0.2797 | 651.5 | 22448.7 | 894003 | 39700000 | 0.3319 | 0.2816 | 0.0000 | 0.0019 | 0.0202 | 0.0000 | 0.0847 | 0.0133 | 0.0605 | 0.0475 | 0.1613 | 0.0665 | 0.2016 | 0.1141 | 0.1855 | 0.1255 | 0.1935 | 0.1464 | 0.0927 | 0.4848 | 0.0000 | 0.0015 | 0.0019 | 0.0000 | 0.0135 | 0.0073 | 0.0250 | 0.0219 | 0.0442 | 0.0335 | 0.0673 | 0.0510 | 0.0635 | 0.0496 | 0.0865 | 0.0700 | 0.6981 | 0.7653 | 0.0000 | 0.0063 | 0.0000 | 0.0063 | 0.0000 | 0.0313 | 0.0478 | 0.0750 | 0.0772 | 0.0938 | 0.1103 | 0.1313 | 0.0809 | 0.1125 | 0.0846 | 0.0875 | 0.5993 | 0.4563 | 0.0051 | 0.0077 | 0.0077 | 0.0281 | 0.0537 | 0.0793 | 0.0793 | 0.0997 | 0.6394 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.0223 | 7.70 | 4.011 | 0.3535 | 30.5 | 195.177 | 1334.83 | 9619.86 | 0.5452 | 0.1074 | 0.0732 | 0.0034 | 0.1616 | 0.0358 | 0.2500 | 0.0903 | 0.2348 | 0.1652 | 0.1372 | 0.2129 | 0.1067 | 0.2215 | 0.0244 | 0.1567 | 0.0091 | 0.0716 | 0.0030 | 0.0426 | 0.0000 | 0.0000 | 0.0070 | 0.0000 | 0.0377 | 0.0061 | 0.0934 | 0.0547 | 0.1506 | 0.1106 | 0.2218 | 0.1385 | 0.1869 | 0.1823 | 0.2050 | 0.2272 | 0.0976 | 0.2807 | 0.0334 | 0.1483 | 0.1517 | 0.3347 | 0.2699 | 0.3051 | 0.2416 | 0.1525 | 0.1645 | 0.0551 | 0.0848 | 0.0042 | 0.0437 | 0.0000 | 0.0103 | 0.0000 | 0.0000 | 0.0000 | 0.0071 | 0.0321 | 0.1214 | 0.1821 | 0.2304 | 0.2054 | 0.1232 | 0.0804 | 0.0179 |
| MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 481 | 100 | | 7950 | 9207 | 278.6 | 129.42 | 10.26 | 12.06 | 144 | 163 | 187 | 215 | 241 | 273 | 314 | 413 | 495 | 0.0924 | 851 | 0.695 | 94.53 | 15.03 | 6 | 0.0267 | 212 | 0.0018 | 9.35 | 6.724 | 0.3596 | 94338.5 | 37400000 | 16500000000 | 7810000000000 | 0.4212 | 0.2162 | 0.0009 | 0.0016 | 0.0013 | 0.0016 | 0.0068 | 0.0043 | 0.0175 | 0.0086 | 0.0554 | 0.0374 | 0.0967 | 0.0491 | 0.0797 | 0.0423 | 0.1121 | 0.0623 | 0.6297 | 0.7930 | 0.0004 | 0.0011 | 0.0007 | 0.0010 | 0.0027 | 0.0027 | 0.0064 | 0.0047 | 0.0202 | 0.0199 | 0.0282 | 0.0236 | 0.0285 | 0.0216 | 0.0407 | 0.0308 | 0.8721 | 0.8946 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0028 | 0.0017 | 0.0070 | 0.0091 | 0.0167 | 0.0205 | 0.0423 | 0.0400 | 0.0265 | 0.0377 | 0.0307 | 0.0354 | 0.8721 | 0.8556 | 0.0010 | 0.0016 | 0.0049 | 0.0092 | 0.0191 | 0.0384 | 0.0309 | 0.0427 | 0.8521 | 3 | 5 | 5 | 6 | 7 | 8 | 9 | 11 | 19 | 0.1322 | 0.45 | 1.509 | 0.5124 | 250.6 | 12213 | 813301 | 62700000 | 0.5153 | 0.1526 | 0.0886 | 0.0079 | 0.2162 | 0.0407 | 0.2503 | 0.0797 | 0.2088 | 0.1421 | 0.1362 | 0.1824 | 0.0696 | 0.1959 | 0.0225 | 0.1743 | 0.0078 | 0.1275 | 0.0000 | 0.0493 | 0.0425 | 0.0045 | 0.1012 | 0.0274 | 0.1320 | 0.0540 | 0.1129 | 0.0995 | 0.0975 | 0.1431 | 0.0935 | 0.1554 | 0.0649 | 0.1304 | 0.0728 | 0.1196 | 0.2827 | 0.2662 | 0.0790 | 0.0376 | 0.0515 | 0.0295 | 0.0334 | 0.0302 | 0.0322 | 0.0376 | 0.0632 | 0.0604 | 0.0971 | 0.1150 | 0.0872 | 0.0825 | 0.0989 | 0.1098 | 0.4576 | 0.4974 | 0.1005 | 0.0895 | 0.0781 | 0.0561 | 0.0570 | 0.0875 | 0.0557 | 0.0858 | 0.3897 | ||
| SK-BR-3 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1220 | 451 | | 11232 | 18145 | 198.9 | 80.62 | 6.13 | 2.92 | 96 | 118 | 138 | 163 | 190 | 224 | 254 | 281 | 308 | 0.0881 | 1598 | 0.402 | 135.09 | 20.03 | 6 | 0.0363 | 408 | 0.0017 | 7.54 | 6.630 | 0.3605 | 46068.3 | 11900000 | 3280000000 | 953000000000 | 0.4257 | 0.1921 | 0.0034 | 0.0015 | 0.0058 | 0.0030 | 0.0089 | 0.0074 | 0.0294 | 0.0164 | 0.0684 | 0.0406 | 0.1042 | 0.0619 | 0.1097 | 0.0584 | 0.1415 | 0.0780 | 0.5287 | 0.7328 | 0.0006 | 0.0003 | 0.0010 | 0.0001 | 0.0022 | 0.0029 | 0.0064 | 0.0067 | 0.0146 | 0.0168 | 0.0254 | 0.0283 | 0.0235 | 0.0230 | 0.0296 | 0.0320 | 0.8967 | 0.8898 | 0.0005 | 0.0025 | 0.0033 | 0.0051 | 0.0060 | 0.0132 | 0.0098 | 0.0229 | 0.0280 | 0.0467 | 0.0282 | 0.0642 | 0.0358 | 0.0778 | 0.0499 | 0.0999 | 0.8385 | 0.6677 | 0.0009 | 0.0007 | 0.0024 | 0.0073 | 0.0189 | 0.0239 | 0.0284 | 0.0375 | 0.8799 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.1305 | 0.44 | 1.002 | 0.4054 | 46.1 | 458.785 | 7687.85 | 234458 | 0.5483 | 0.1268 | 0.0123 | 0.0015 | 0.0555 | 0.0107 | 0.1399 | 0.0297 | 0.2151 | 0.0734 | 0.2476 | 0.1533 | 0.1919 | 0.2308 | 0.1031 | 0.2579 | 0.0306 | 0.1797 | 0.0042 | 0.0631 | 0.0008 | 0.0001 | 0.0083 | 0.0014 | 0.0270 | 0.0074 | 0.0633 | 0.0263 | 0.1189 | 0.0658 | 0.1643 | 0.1156 | 0.2017 | 0.2003 | 0.2201 | 0.2840 | 0.1956 | 0.2992 | 0.1197 | 0.2233 | 0.1816 | 0.2100 | 0.1733 | 0.1903 | 0.1579 | 0.1256 | 0.1231 | 0.0803 | 0.0916 | 0.0538 | 0.0625 | 0.0439 | 0.0525 | 0.0381 | 0.0379 | 0.0347 | 0.0066 | 0.0454 | 0.0962 | 0.1383 | 0.1787 | 0.1873 | 0.1512 | 0.1164 | 0.0797 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 927 | 887 | | 3637 | 16754 | 208.9 | 92.53 | 65.01 | 116.76 | 121 | 135 | 144 | 158 | 179 | 205 | 235 | 270 | 358 | 0.0556 | 932 | 0.834 | 150.33 | 54.74 | 2 | 0.1270 | 462 | 0.0037 | 12.92 | 6.141 | 0.3836 | 52205.7 | 15500000 | 5250000000 | 1970000000000 | 0.4763 | 0.1819 | 0.0019 | 0.0015 | 0.0029 | 0.0023 | 0.0229 | 0.0034 | 0.0381 | 0.0138 | 0.0705 | 0.0356 | 0.0896 | 0.0521 | 0.0925 | 0.0502 | 0.1211 | 0.0705 | 0.5605 | 0.7705 | 0.0010 | 0.0013 | 0.0010 | 0.0016 | 0.0050 | 0.0022 | 0.0076 | 0.0094 | 0.0222 | 0.0216 | 0.0443 | 0.0388 | 0.0267 | 0.0297 | 0.0489 | 0.0503 | 0.8433 | 0.8452 | 0.0021 | 0.0000 | 0.0011 | 0.0068 | 0.0064 | 0.0034 | 0.0139 | 0.0051 | 0.0502 | 0.0425 | 0.0694 | 0.0969 | 0.0491 | 0.0459 | 0.0780 | 0.0986 | 0.7297 | 0.7007 | 0.0014 | 0.0021 | 0.0014 | 0.0057 | 0.0291 | 0.0704 | 0.0455 | 0.0824 | 0.7619 | 5 | 7 | 8 | 10 | 13 | 21 | 44 | 90 | 198 | 0.1255 | 5.70 | 3.389 | 0.6022 | 17857.4 | 7770000 | 4140000000 | 2500000000000 | 0.4976 | 0.1519 | 0.0344 | 0.0046 | 0.1527 | 0.0207 | 0.2796 | 0.0718 | 0.1989 | 0.1314 | 0.1452 | 0.1840 | 0.0882 | 0.2058 | 0.0527 | 0.1436 | 0.0312 | 0.1193 | 0.0172 | 0.1188 | 0.0002 | 0.0009 | 0.0019 | 0.0019 | 0.0043 | 0.0024 | 0.0143 | 0.0145 | 0.0517 | 0.0443 | 0.0853 | 0.0765 | 0.0530 | 0.0575 | 0.0866 | 0.0815 | 0.7027 | 0.7204 | 0.0003 | 0.0012 | 0.0024 | 0.0039 | 0.0053 | 0.0051 | 0.0173 | 0.0170 | 0.0587 | 0.0670 | 0.1025 | 0.1053 | 0.0672 | 0.0804 | 0.1014 | 0.1071 | 0.6449 | 0.6130 | 0.0012 | 0.0022 | 0.0050 | 0.0146 | 0.0566 | 0.0853 | 0.0609 | 0.1035 | 0.6707 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 332 | 897 | | 4130 | 6420 | 525.0 | 190.33 | 45.50 | 77.20 | 256 | 314 | 388 | 474 | 542 | 599 | 659 | 716 | 767 | 0.1092 | 701 | 0.638 | 84.10 | 14.14 | 5 | 0.0482 | 199 | 0.0007 | 53.48 | 7.439 | 0.1929 | 311857.0 | 201000000 | 138000000000 | 98300000000000 | 0.3906 | 0.2301 | 0.0000 | 0.0015 | 0.0031 | 0.0011 | 0.0168 | 0.0011 | 0.0291 | 0.0083 | 0.1034 | 0.0496 | 0.1516 | 0.0931 | 0.1309 | 0.0644 | 0.1072 | 0.0966 | 0.4579 | 0.6842 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0033 | 0.0018 | 0.0328 | 0.0255 | 0.0470 | 0.0436 | 0.0303 | 0.0252 | 0.0445 | 0.0370 | 0.8418 | 0.8670 | 0.0000 | 0.0015 | 0.0000 | 0.0046 | 0.0021 | 0.0167 | 0.0104 | 0.0410 | 0.0494 | 0.0819 | 0.0626 | 0.1335 | 0.0494 | 0.1108 | 0.0745 | 0.1457 | 0.7516 | 0.4643 | 0.0000 | 0.0005 | 0.0005 | 0.0045 | 0.0352 | 0.0587 | 0.0352 | 0.0564 | 0.8090 | 8 | 10 | 13 | 15 | 17 | 22 | 31 | 60 | 119 | 0.0622 | 10.67 | 3.904 | 0.6364 | 8028.7 | 3400000 | 2280000000 | 1870000000000 | 0.5362 | 0.1440 | 0.0369 | 0.0169 | 0.0844 | 0.0226 | 0.1082 | 0.0463 | 0.1504 | 0.0993 | 0.1847 | 0.1366 | 0.1821 | 0.1061 | 0.1372 | 0.1163 | 0.0976 | 0.1558 | 0.0185 | 0.3002 | 0.0017 | 0.0057 | 0.0034 | 0.0076 | 0.0040 | 0.0086 | 0.0115 | 0.0195 | 0.0453 | 0.0437 | 0.0539 | 0.0518 | 0.0441 | 0.0456 | 0.0648 | 0.0699 | 0.7713 | 0.7476 | 0.0007 | 0.0025 | 0.0029 | 0.0016 | 0.0102 | 0.0074 | 0.0154 | 0.0164 | 0.0469 | 0.0402 | 0.0608 | 0.0731 | 0.0490 | 0.0484 | 0.0791 | 0.0649 | 0.7350 | 0.7455 | 0.0006 | 0.0051 | 0.0058 | 0.0135 | 0.0398 | 0.0630 | 0.0424 | 0.0694 | 0.7603 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 382 | 482 | | 6733 | 6438 | 43.2 | 12.21 | 112.41 | 165.59 | 28 | 32 | 35 | 39 | 42 | 46 | 50 | 54 | 60 | 0.1785 | 1149 | 1.039 | 54.34 | 16.16 | 3 | 0.0192 | 129 | 0.0360 | 0.84 | 3.592 | 0.6983 | 2014.6 | 100311 | 5270000 | 290000000 | 0.3887 | 0.2344 | 0.0060 | 0.0014 | 0.0139 | 0.0039 | 0.0220 | 0.0043 | 0.0460 | 0.0107 | 0.0794 | 0.0318 | 0.1389 | 0.0469 | 0.1480 | 0.0529 | 0.1880 | 0.0959 | 0.3578 | 0.7522 | 0.0027 | 0.0005 | 0.0041 | 0.0010 | 0.0078 | 0.0010 | 0.0188 | 0.0052 | 0.0347 | 0.0229 | 0.0580 | 0.0316 | 0.0586 | 0.0321 | 0.0858 | 0.0495 | 0.7295 | 0.8563 | 0.0070 | 0.0313 | 0.0186 | 0.0224 | 0.0256 | 0.0328 | 0.0413 | 0.0627 | 0.0721 | 0.0687 | 0.0809 | 0.1224 | 0.0878 | 0.1328 | 0.1268 | 0.1597 | 0.5398 | 0.3672 | 0.0033 | 0.0090 | 0.0189 | 0.0269 | 0.0452 | 0.0619 | 0.0736 | 0.0984 | 0.6628 | 7 | 8 | 10 | 12 | 19 | 48 | 124 | 221 | 345 | 0.0718 | 6.66 | 3.779 | 0.5031 | 40050.5 | 19600000 | 11300000000 | 7260000000000 | 0.4549 | 0.1859 | 0.0359 | 0.0046 | 0.1257 | 0.0170 | 0.2036 | 0.0880 | 0.1916 | 0.1173 | 0.1796 | 0.1867 | 0.1168 | 0.1929 | 0.0778 | 0.1312 | 0.0539 | 0.1281 | 0.0150 | 0.1343 | 0.0005 | 0.0008 | 0.0014 | 0.0021 | 0.0023 | 0.0008 | 0.0087 | 0.0068 | 0.0407 | 0.0343 | 0.0535 | 0.0525 | 0.0512 | 0.0423 | 0.0699 | 0.0728 | 0.7719 | 0.7875 | 0.0005 | 0.0000 | 0.0000 | 0.0012 | 0.0022 | 0.0041 | 0.0097 | 0.0146 | 0.0529 | 0.0578 | 0.0707 | 0.0776 | 0.0723 | 0.0712 | 0.0960 | 0.0968 | 0.6958 | 0.6768 | 0.0000 | 0.0010 | 0.0035 | 0.0144 | 0.0416 | 0.0575 | 0.0615 | 0.0878 | 0.7328 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1017 | 174 | | 1248 | 1851 | 214.5 | 155.04 | 45.32 | 44.12 | 105 | 122 | 135 | 145 | 159 | 175 | 196 | 246 | 453 | 0.2150 | 398 | 0.886 | 138.05 | 45.25 | 2 | 0.3045 | 380 | 0.0030 | 54.71 | 6.166 | 0.2695 | 70037.8 | 33300000 | 19600000000 | 12700000000000 | 0.3408 | 0.2642 | 0.0000 | 0.0014 | 0.0105 | 0.0000 | 0.0592 | 0.0027 | 0.0941 | 0.0095 | 0.2056 | 0.0846 | 0.1638 | 0.1419 | 0.0906 | 0.1132 | 0.1289 | 0.1050 | 0.2474 | 0.5416 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0076 | 0.0011 | 0.0191 | 0.0085 | 0.0841 | 0.0512 | 0.1071 | 0.0800 | 0.0650 | 0.0597 | 0.1071 | 0.0778 | 0.6099 | 0.7207 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0169 | 0.0098 | 0.0805 | 0.1073 | 0.1059 | 0.1024 | 0.0551 | 0.0488 | 0.0975 | 0.1024 | 0.6441 | 0.6293 | 0.0032 | 0.0097 | 0.0097 | 0.0130 | 0.0909 | 0.0942 | 0.0390 | 0.1039 | 0.6364 | 20 | 22 | 25 | 27 | 30 | 34 | 39 | 51 | 87 | 0.1634 | 0.96 | 2.528 | 0.7872 | 4000.0 | 623754 | 127000000 | 29000000000 | 0.5672 | 0.0956 | 0.0344 | 0.0145 | 0.0875 | 0.0190 | 0.1375 | 0.0335 | 0.1313 | 0.0760 | 0.1906 | 0.1229 | 0.2000 | 0.1508 | 0.1156 | 0.1620 | 0.0688 | 0.1721 | 0.0344 | 0.2492 | 0.0106 | 0.0111 | 0.0257 | 0.0146 | 0.0287 | 0.0231 | 0.0332 | 0.0446 | 0.0861 | 0.0788 | 0.1344 | 0.0925 | 0.1239 | 0.1071 | 0.1360 | 0.1500 | 0.4215 | 0.4781 | 0.0029 | 0.0037 | 0.0088 | 0.0368 | 0.0205 | 0.0404 | 0.0526 | 0.0772 | 0.1404 | 0.0919 | 0.1725 | 0.1287 | 0.1023 | 0.1213 | 0.1287 | 0.1103 | 0.3713 | 0.3897 | 0.0022 | 0.0155 | 0.0310 | 0.0376 | 0.1062 | 0.1372 | 0.1261 | 0.1482 | 0.3960 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 958 | 125 | | 2932 | 10604 | 196.6 | 65.96 | 9.01 | 4.41 | 127 | 138 | 150 | 164 | 179 | 198 | 223 | 249 | 301 | 0.0658 | 698 | 0.614 | 76.01 | 21.95 | 1 | 0.0836 | 245 | 0.0079 | 2.74 | 5.180 | 0.5006 | 42980.6 | 10400000 | 2760000000 | 788000000000 | 0.4076 | 0.2304 | 0.0043 | 0.0013 | 0.0035 | 0.0013 | 0.0112 | 0.0042 | 0.0371 | 0.0097 | 0.0569 | 0.0295 | 0.1320 | 0.0687 | 0.1217 | 0.0442 | 0.1639 | 0.0720 | 0.4694 | 0.7692 | 0.0021 | 0.0011 | 0.0021 | 0.0007 | 0.0053 | 0.0032 | 0.0137 | 0.0064 | 0.0217 | 0.0207 | 0.0455 | 0.0454 | 0.0418 | 0.0264 | 0.0561 | 0.0482 | 0.8117 | 0.8477 | 0.0014 | 0.0000 | 0.0014 | 0.0000 | 0.0109 | 0.0047 | 0.0301 | 0.0165 | 0.0342 | 0.0425 | 0.0861 | 0.0778 | 0.0697 | 0.0472 | 0.0765 | 0.0802 | 0.6899 | 0.7311 | 0.0017 | 0.0025 | 0.0042 | 0.0151 | 0.0260 | 0.0519 | 0.0511 | 0.0611 | 0.7864 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 14 | 0.0111 | 13.72 | 5.076 | 0.3038 | 100.7 | 1416.1 | 25055.2 | 539238 | 0.4587 | 0.1802 | 0.0400 | 0.0040 | 0.1247 | 0.0070 | 0.2092 | 0.0206 | 0.2582 | 0.0465 | 0.1991 | 0.1010 | 0.1141 | 0.1792 | 0.0447 | 0.2550 | 0.0098 | 0.2595 | 0.0003 | 0.1273 | 0.0087 | 0.0002 | 0.0392 | 0.0012 | 0.0841 | 0.0078 | 0.1282 | 0.0233 | 0.1444 | 0.0654 | 0.1470 | 0.1201 | 0.1169 | 0.1781 | 0.1209 | 0.2377 | 0.2107 | 0.3662 | 0.1147 | 0.1071 | 0.0900 | 0.0750 | 0.0862 | 0.0679 | 0.0718 | 0.0968 | 0.0938 | 0.0859 | 0.1045 | 0.1000 | 0.0836 | 0.1019 | 0.0957 | 0.1167 | 0.2595 | 0.2487 | 0.0483 | 0.0956 | 0.1102 | 0.1089 | 0.1085 | 0.0986 | 0.0902 | 0.1128 | 0.2269 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 176 | 439 | | 2149 | 10252 | 192.6 | 59.91 | 8.87 | 3.44 | 120 | 133 | 148 | 165 | 184 | 205 | 228 | 254 | 283 | 0.0694 | 712 | 0.822 | 57.98 | 20.03 | 1 | 0.0814 | 175 | 0.0084 | 2.12 | 4.986 | 0.5414 | 40700.9 | 9310000 | 2270000000 | 578000000000 | 0.3740 | 0.2645 | 0.0013 | 0.0012 | 0.0076 | 0.0030 | 0.0076 | 0.0041 | 0.0278 | 0.0100 | 0.0682 | 0.0349 | 0.1174 | 0.0573 | 0.1023 | 0.0473 | 0.1452 | 0.0810 | 0.5227 | 0.7612 | 0.0000 | 0.0010 | 0.0043 | 0.0020 | 0.0021 | 0.0030 | 0.0100 | 0.0070 | 0.0242 | 0.0214 | 0.0356 | 0.0349 | 0.0342 | 0.0244 | 0.0456 | 0.0449 | 0.8439 | 0.8614 | 0.0000 | 0.0064 | 0.0000 | 0.0032 | 0.0065 | 0.0127 | 0.0196 | 0.0255 | 0.0344 | 0.0541 | 0.0687 | 0.0637 | 0.0507 | 0.0732 | 0.0589 | 0.0669 | 0.7610 | 0.6943 | 0.0000 | 0.0000 | 0.0072 | 0.0196 | 0.0319 | 0.0330 | 0.0484 | 0.0649 | 0.7951 | 5 | 6 | 7 | 8 | 8 | 9 | 10 | 11 | 13 | 0.0123 | 12.27 | 4.870 | 0.3144 | 90.5 | 1065.26 | 14510.9 | 227463 | 0.4586 | 0.1831 | 0.0295 | 0.0009 | 0.1028 | 0.0024 | 0.1962 | 0.0094 | 0.2565 | 0.0319 | 0.2244 | 0.0719 | 0.1268 | 0.1660 | 0.0511 | 0.2677 | 0.0112 | 0.2954 | 0.0016 | 0.1543 | 0.0050 | 0.0000 | 0.0247 | 0.0004 | 0.0691 | 0.0026 | 0.1247 | 0.0146 | 0.1520 | 0.0414 | 0.1628 | 0.1000 | 0.1487 | 0.1803 | 0.1348 | 0.2780 | 0.1782 | 0.3828 | 0.1256 | 0.1981 | 0.1426 | 0.1338 | 0.1343 | 0.1060 | 0.1181 | 0.0730 | 0.1121 | 0.0782 | 0.0895 | 0.0773 | 0.0642 | 0.0695 | 0.0701 | 0.0712 | 0.1434 | 0.1929 | 0.0242 | 0.0702 | 0.1099 | 0.1423 | 0.1381 | 0.1306 | 0.1204 | 0.1069 | 0.1574 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 162 | 234 | | 7241 | 33553 | 311.8 | 96.47 | 118.63 | 162.69 | 187 | 201 | 237 | 287 | 318 | 345 | 372 | 400 | 436 | 0.0350 | 1175 | 0.651 | 97.19 | 15.30 | 2 | 0.0305 | 221 | 0.0011 | 37.81 | 7.274 | 0.2128 | 106500.0 | 39100000 | 15200000000 | 6200000000000 | 0.4774 | 0.1776 | 0.0004 | 0.0012 | 0.0025 | 0.0024 | 0.0078 | 0.0057 | 0.0252 | 0.0134 | 0.0900 | 0.0431 | 0.1460 | 0.0745 | 0.1488 | 0.0709 | 0.1729 | 0.1150 | 0.4064 | 0.6737 | 0.0000 | 0.0011 | 0.0000 | 0.0020 | 0.0012 | 0.0045 | 0.0020 | 0.0085 | 0.0163 | 0.0263 | 0.0285 | 0.0387 | 0.0281 | 0.0343 | 0.0386 | 0.0461 | 0.8853 | 0.8385 | 0.0024 | 0.0155 | 0.0043 | 0.0127 | 0.0119 | 0.0325 | 0.0396 | 0.0876 | 0.0835 | 0.1441 | 0.1098 | 0.1935 | 0.1150 | 0.1483 | 0.1394 | 0.1384 | 0.4940 | 0.2274 | 0.0000 | 0.0011 | 0.0029 | 0.0135 | 0.0296 | 0.0630 | 0.0643 | 0.0849 | 0.7407 | 9 | 11 | 14 | 19 | 34 | 73 | 138 | 222 | 342 | 0.1019 | 11.63 | 4.467 | 0.5909 | 40541.7 | 20200000 | 12600000000 | 9300000000000 | 0.3536 | 0.3217 | 0.0195 | 0.0035 | 0.1006 | 0.0081 | 0.1840 | 0.0477 | 0.1733 | 0.1043 | 0.1800 | 0.1722 | 0.1418 | 0.1779 | 0.1082 | 0.1344 | 0.0594 | 0.1368 | 0.0332 | 0.2151 | 0.0001 | 0.0006 | 0.0006 | 0.0005 | 0.0020 | 0.0011 | 0.0085 | 0.0076 | 0.0341 | 0.0295 | 0.0563 | 0.0485 | 0.0428 | 0.0362 | 0.0619 | 0.0541 | 0.7937 | 0.8219 | 0.0001 | 0.0002 | 0.0013 | 0.0015 | 0.0028 | 0.0035 | 0.0110 | 0.0135 | 0.0448 | 0.0478 | 0.0745 | 0.0869 | 0.0567 | 0.0645 | 0.0842 | 0.0980 | 0.7246 | 0.6843 | 0.0002 | 0.0009 | 0.0028 | 0.0099 | 0.0385 | 0.0629 | 0.0519 | 0.0705 | 0.7623 |
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 645 | 729 | | 1042 | 10329 | 562.4 | 153.48 | 8.59 | 2.99 | 395 | 423 | 449 | 479 | 518 | 570 | 632 | 713 | 801 | 0.0578 | 597 | 0.406 | 38.95 | 6.00 | 1 | 0.1344 | 140 | 0.0020 | 28.18 | 6.374 | 0.1954 | 339826.0 | 220000000 | 152000000000 | 110000000000000 | 0.4086 | 0.2249 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0212 | 0.0033 | 0.1017 | 0.0499 | 0.1737 | 0.0684 | 0.1504 | 0.0543 | 0.1822 | 0.0934 | 0.3708 | 0.7296 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0010 | 0.0412 | 0.0345 | 0.0686 | 0.0432 | 0.0521 | 0.0288 | 0.0782 | 0.0518 | 0.7476 | 0.8407 | 0.0000 | 0.0083 | 0.0000 | 0.0000 | 0.0000 | 0.0248 | 0.0311 | 0.0496 | 0.0778 | 0.0992 | 0.1051 | 0.1157 | 0.0856 | 0.1074 | 0.0895 | 0.0992 | 0.6109 | 0.4959 | 0.0000 | 0.0000 | 0.0000 | 0.0094 | 0.0587 | 0.0915 | 0.0493 | 0.0822 | 0.7089 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 13 | 0.0126 | 8.42 | 4.763 | 0.3488 | 82.8 | 880.135 | 10198.1 | 127270 | 0.4495 | 0.1810 | 0.0600 | 0.0013 | 0.1168 | 0.0074 | 0.1774 | 0.0227 | 0.2182 | 0.0459 | 0.2039 | 0.0693 | 0.1400 | 0.1259 | 0.0611 | 0.1879 | 0.0197 | 0.2819 | 0.0029 | 0.2578 | 0.0209 | 0.0001 | 0.0384 | 0.0037 | 0.0525 | 0.0120 | 0.0714 | 0.0250 | 0.0846 | 0.0391 | 0.1058 | 0.0659 | 0.1247 | 0.1005 | 0.1743 | 0.1835 | 0.3273 | 0.5701 | 0.0655 | 0.0973 | 0.0800 | 0.1227 | 0.0883 | 0.1578 | 0.1065 | 0.1446 | 0.1242 | 0.1437 | 0.1356 | 0.1420 | 0.1479 | 0.1060 | 0.1487 | 0.0640 | 0.1033 | 0.0219 | 0.0340 | 0.0642 | 0.0722 | 0.0754 | 0.0867 | 0.1099 | 0.1315 | 0.1726 | 0.2535 |
| SK-BR-3 | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 328 | 685 | | 3310 | 17319 | 115.5 | 44.52 | 5.43 | 1.99 | 62 | 70 | 80 | 93 | 109 | 124 | 140 | 161 | 181 | 0.0577 | 999 | 0.991 | 31.40 | 10.77 | 2 | 0.0266 | 88 | 0.0050 | 4.21 | 5.619 | 0.4414 | 15310.3 | 2260000 | 362000000 | 61100000000 | 0.3498 | 0.2779 | 0.0021 | 0.0010 | 0.0072 | 0.0039 | 0.0123 | 0.0093 | 0.0349 | 0.0181 | 0.0739 | 0.0366 | 0.1242 | 0.0439 | 0.1232 | 0.0649 | 0.1828 | 0.0825 | 0.4394 | 0.7399 | 0.0005 | 0.0007 | 0.0015 | 0.0026 | 0.0035 | 0.0048 | 0.0089 | 0.0096 | 0.0212 | 0.0177 | 0.0227 | 0.0184 | 0.0257 | 0.0302 | 0.0420 | 0.0350 | 0.8741 | 0.8809 | 0.0010 | 0.0000 | 0.0019 | 0.0045 | 0.0086 | 0.0106 | 0.0209 | 0.0151 | 0.0409 | 0.0452 | 0.0571 | 0.0603 | 0.0523 | 0.0724 | 0.0647 | 0.0799 | 0.7526 | 0.7119 | 0.0013 | 0.0000 | 0.0013 | 0.0097 | 0.0232 | 0.0387 | 0.0290 | 0.0574 | 0.8395 | 3 | 4 | 4 | 5 | 5 | 6 | 6 | 7 | 8 | 0.2714 | 0.47 | 1.049 | 0.6358 | 33.5 | 227.156 | 1669.44 | 13153.9 | 0.4485 | 0.2089 | 0.0313 | 0.0023 | 0.0940 | 0.0125 | 0.1602 | 0.0406 | 0.2077 | 0.0829 | 0.2080 | 0.1416 | 0.1737 | 0.2164 | 0.0888 | 0.2463 | 0.0321 | 0.1826 | 0.0043 | 0.0747 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0030 | 0.0008 | 0.0099 | 0.0050 | 0.0301 | 0.0153 | 0.0780 | 0.0258 | 0.2017 | 0.0630 | 0.3485 | 0.2345 | 0.3287 | 0.6554 | 0.0177 | 0.0768 | 0.0775 | 0.1643 | 0.1302 | 0.2136 | 0.1742 | 0.2130 | 0.1942 | 0.1573 | 0.1860 | 0.0951 | 0.1327 | 0.0548 | 0.0683 | 0.0195 | 0.0192 | 0.0057 | 0.0007 | 0.0109 | 0.0459 | 0.1123 | 0.1876 | 0.2387 | 0.2118 | 0.1393 | 0.0528 |