High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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Hs 578T | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 283 | 97 | 3964 | 10522 | 352.2 | 81.30 | 461.34 | 382.37 | 252 | 288 | 313 | 334 | 354 | 372 | 392 | 416 | 452 | 0.0657 | 691 | 0.753 | 95.27 | 24.08 | 1 | 0.0658 | 261 | 0.0006 | 102.74 | 7.612 | 0.1258 | 130633.0 | 50600000 | 20400000000 | 8530000000000 | 0.4023 | 0.2386 | 0.0008 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0000 | 0.0179 | 0.0014 | 0.0550 | 0.0209 | 0.1072 | 0.0390 | 0.1228 | 0.0329 | 0.1454 | 0.0549 | 0.5458 | 0.8510 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0009 | 0.0000 | 0.0061 | 0.0013 | 0.0223 | 0.0154 | 0.0444 | 0.0260 | 0.0471 | 0.0172 | 0.0640 | 0.0262 | 0.8145 | 0.9139 | 0.0000 | 0.0109 | 0.0100 | 0.0109 | 0.0242 | 0.0217 | 0.0627 | 0.1033 | 0.1296 | 0.1467 | 0.1553 | 0.1413 | 0.1254 | 0.1196 | 0.1538 | 0.1033 | 0.3390 | 0.3424 | 0.0010 | 0.0035 | 0.0049 | 0.0233 | 0.0673 | 0.1054 | 0.1049 | 0.1242 | 0.5656 | 46 | 92 | 175 | 276 | 376 | 494 | 622 | 777 | 1000 | 0.0020 | 93.98 | 7.546 | 0.2428 | 359026.0 | 355000000 | 407000000000 | 521000000000000 | 0.5626 | 0.1363 | 0.0068 | 0.0015 | 0.0542 | 0.0057 | 0.1423 | 0.0121 | 0.1725 | 0.0508 | 0.1725 | 0.1309 | 0.1744 | 0.1967 | 0.1072 | 0.1517 | 0.0930 | 0.1565 | 0.0770 | 0.2940 | 0.0004 | 0.0000 | 0.0039 | 0.0011 | 0.0049 | 0.0030 | 0.0161 | 0.0105 | 0.0447 | 0.0377 | 0.0709 | 0.0692 | 0.0629 | 0.0510 | 0.0765 | 0.0729 | 0.7196 | 0.7546 | 0.0008 | 0.0007 | 0.0027 | 0.0023 | 0.0065 | 0.0073 | 0.0220 | 0.0293 | 0.0578 | 0.0676 | 0.0957 | 0.1119 | 0.0774 | 0.0916 | 0.1013 | 0.1196 | 0.6358 | 0.5696 | 0.0002 | 0.0022 | 0.0038 | 0.0146 | 0.0510 | 0.0864 | 0.0649 | 0.0858 | 0.6910 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 781 | 933 | 4650 | 7671 | 149.2 | 35.80 | 272.55 | 157.57 | 110 | 120 | 127 | 134 | 142 | 151 | 162 | 176 | 198 | 0.0948 | 727 | 1.075 | 97.75 | 27.80 | 1 | 0.0520 | 242 | 0.0020 | 26.81 | 6.558 | 0.2363 | 23531.1 | 3940000 | 699000000 | 132000000000 | 0.4493 | 0.1999 | 0.0003 | 0.0000 | 0.0017 | 0.0000 | 0.0104 | 0.0002 | 0.0338 | 0.0009 | 0.0898 | 0.0243 | 0.1628 | 0.0471 | 0.1597 | 0.0468 | 0.1837 | 0.0695 | 0.3577 | 0.8111 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0027 | 0.0002 | 0.0118 | 0.0004 | 0.0454 | 0.0150 | 0.0668 | 0.0232 | 0.0778 | 0.0163 | 0.1088 | 0.0306 | 0.6864 | 0.9142 | 0.0023 | 0.0030 | 0.0092 | 0.0060 | 0.0358 | 0.0329 | 0.0796 | 0.0928 | 0.1476 | 0.1707 | 0.1857 | 0.2335 | 0.1153 | 0.1138 | 0.1361 | 0.1707 | 0.2884 | 0.1766 | 0.0020 | 0.0035 | 0.0111 | 0.0308 | 0.0968 | 0.1402 | 0.1160 | 0.1452 | 0.4544 | 91 | 134 | 171 | 208 | 247 | 291 | 338 | 395 | 486 | 0.0007 | 96.75 | 7.538 | 0.1758 | 99105.9 | 44100000 | 22800000000 | 13300000000000 | 0.5485 | 0.1214 | 0.0151 | 0.0008 | 0.0764 | 0.0058 | 0.1871 | 0.0233 | 0.1861 | 0.0595 | 0.2027 | 0.1375 | 0.1554 | 0.2135 | 0.0941 | 0.1857 | 0.0520 | 0.1666 | 0.0312 | 0.2074 | 0.0009 | 0.0002 | 0.0030 | 0.0007 | 0.0077 | 0.0036 | 0.0219 | 0.0100 | 0.0743 | 0.0552 | 0.1272 | 0.1019 | 0.1078 | 0.0886 | 0.1429 | 0.1166 | 0.5144 | 0.6232 | 0.0008 | 0.0053 | 0.0106 | 0.0148 | 0.0203 | 0.0373 | 0.0519 | 0.0841 | 0.1339 | 0.1587 | 0.1729 | 0.1829 | 0.1303 | 0.1533 | 0.1652 | 0.1385 | 0.3141 | 0.2250 | 0.0009 | 0.0051 | 0.0146 | 0.0363 | 0.0991 | 0.1479 | 0.1303 | 0.1511 | 0.4148 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 387 | 433 | 5231 | 10050 | 128.6 | 29.95 | 253.02 | 164.61 | 95 | 106 | 112 | 118 | 124 | 131 | 139 | 149 | 167 | 0.0766 | 770 | 1.025 | 94.58 | 21.95 | 1 | 0.0417 | 218 | 0.0027 | 19.06 | 6.270 | 0.2625 | 17434.3 | 2500000 | 381000000 | 61800000000 | 0.4642 | 0.1924 | 0.0009 | 0.0000 | 0.0012 | 0.0004 | 0.0063 | 0.0008 | 0.0155 | 0.0006 | 0.0748 | 0.0204 | 0.1327 | 0.0433 | 0.1376 | 0.0474 | 0.1804 | 0.0775 | 0.4506 | 0.8094 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0025 | 0.0004 | 0.0058 | 0.0004 | 0.0353 | 0.0138 | 0.0679 | 0.0272 | 0.0616 | 0.0216 | 0.0981 | 0.0325 | 0.7281 | 0.9042 | 0.0035 | 0.0236 | 0.0058 | 0.0505 | 0.0256 | 0.0337 | 0.0816 | 0.0741 | 0.1457 | 0.1886 | 0.1620 | 0.1818 | 0.1550 | 0.0976 | 0.1352 | 0.1515 | 0.2855 | 0.1987 | 0.0022 | 0.0065 | 0.0113 | 0.0427 | 0.0946 | 0.1325 | 0.1176 | 0.1451 | 0.4475 | 60 | 102 | 143 | 183 | 224 | 272 | 324 | 390 | 488 | 0.0010 | 93.19 | 7.522 | 0.1835 | 91109.9 | 40300000 | 20400000000 | 11500000000000 | 0.4846 | 0.1715 | 0.0159 | 0.0002 | 0.0785 | 0.0058 | 0.2247 | 0.0267 | 0.1565 | 0.0755 | 0.1770 | 0.1506 | 0.1499 | 0.1952 | 0.0887 | 0.1576 | 0.0612 | 0.1601 | 0.0476 | 0.2282 | 0.0009 | 0.0000 | 0.0011 | 0.0015 | 0.0050 | 0.0019 | 0.0179 | 0.0119 | 0.0651 | 0.0482 | 0.1005 | 0.0787 | 0.0938 | 0.0705 | 0.1206 | 0.1004 | 0.5951 | 0.6868 | 0.0012 | 0.0036 | 0.0041 | 0.0052 | 0.0106 | 0.0203 | 0.0361 | 0.0584 | 0.0993 | 0.1247 | 0.1704 | 0.1918 | 0.1202 | 0.1275 | 0.1539 | 0.1485 | 0.4042 | 0.3201 | 0.0002 | 0.0034 | 0.0073 | 0.0241 | 0.0768 | 0.1375 | 0.1128 | 0.1355 | 0.5024 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 819 | 837 | 4077 | 7402 | 164.0 | 45.49 | 281.51 | 208.60 | 106 | 126 | 139 | 150 | 161 | 172 | 185 | 201 | 225 | 0.0809 | 599 | 0.666 | 68.59 | 22.56 | 2 | 0.0518 | 211 | 0.0013 | 30.19 | 6.879 | 0.2104 | 28976.0 | 5470000 | 1100000000 | 232000000000 | 0.4785 | 0.1795 | 0.0028 | 0.0000 | 0.0032 | 0.0006 | 0.0065 | 0.0020 | 0.0341 | 0.0061 | 0.1138 | 0.0314 | 0.1876 | 0.0802 | 0.1618 | 0.0709 | 0.1834 | 0.0994 | 0.3069 | 0.7095 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0019 | 0.0005 | 0.0081 | 0.0026 | 0.0430 | 0.0195 | 0.0783 | 0.0445 | 0.0608 | 0.0306 | 0.0935 | 0.0458 | 0.7126 | 0.8562 | 0.0043 | 0.0113 | 0.0185 | 0.0226 | 0.0120 | 0.0452 | 0.0663 | 0.1271 | 0.1261 | 0.1582 | 0.1815 | 0.2345 | 0.1239 | 0.1356 | 0.1424 | 0.0989 | 0.3250 | 0.1667 | 0.0015 | 0.0021 | 0.0072 | 0.0355 | 0.0762 | 0.1340 | 0.1061 | 0.1175 | 0.5198 | 41 | 86 | 136 | 190 | 247 | 308 | 370 | 448 | 564 | 0.0018 | 128.90 | 7.431 | 0.1991 | 122752.0 | 67400000 | 43400000000 | 31600000000000 | 0.5494 | 0.1250 | 0.0218 | 0.0004 | 0.1102 | 0.0047 | 0.2408 | 0.0505 | 0.1748 | 0.0920 | 0.1769 | 0.1749 | 0.1363 | 0.2080 | 0.0798 | 0.1531 | 0.0428 | 0.1385 | 0.0167 | 0.1778 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0035 | 0.0011 | 0.0151 | 0.0089 | 0.0627 | 0.0498 | 0.1204 | 0.0924 | 0.0929 | 0.0759 | 0.1327 | 0.1043 | 0.5715 | 0.6676 | 0.0000 | 0.0020 | 0.0042 | 0.0036 | 0.0096 | 0.0137 | 0.0301 | 0.0493 | 0.1131 | 0.1301 | 0.1521 | 0.1876 | 0.1212 | 0.1256 | 0.1613 | 0.1520 | 0.4083 | 0.3360 | 0.0015 | 0.0024 | 0.0049 | 0.0182 | 0.0809 | 0.1469 | 0.1031 | 0.1338 | 0.5082 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 341 | 154 | 3660 | 2741 | 145.1 | 40.32 | 362.39 | 193.78 | 100 | 113 | 122 | 131 | 139 | 148 | 158 | 173 | 199 | 0.1423 | 390 | 0.690 | 91.44 | 18.79 | 1 | 0.0628 | 230 | 0.0017 | 31.24 | 6.666 | 0.2130 | 22685.8 | 3840000 | 708000000 | 142000000000 | 0.4590 | 0.1971 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0099 | 0.0000 | 0.0292 | 0.0034 | 0.0887 | 0.0281 | 0.1651 | 0.0650 | 0.1547 | 0.0625 | 0.1731 | 0.0940 | 0.3774 | 0.7470 | 0.0004 | 0.0000 | 0.0011 | 0.0000 | 0.0018 | 0.0000 | 0.0113 | 0.0020 | 0.0389 | 0.0146 | 0.0752 | 0.0346 | 0.0724 | 0.0242 | 0.0947 | 0.0466 | 0.7043 | 0.8781 | 0.0056 | 0.0031 | 0.0042 | 0.0061 | 0.0225 | 0.0429 | 0.0591 | 0.0982 | 0.1224 | 0.1595 | 0.1758 | 0.2178 | 0.1097 | 0.1012 | 0.1280 | 0.1380 | 0.3727 | 0.2331 | 0.0000 | 0.0056 | 0.0175 | 0.0437 | 0.0936 | 0.1392 | 0.1180 | 0.1311 | 0.4513 | 105 | 176 | 244 | 302 | 359 | 408 | 457 | 521 | 616 | 0.0007 | 113.79 | 7.416 | 0.1244 | 168859.0 | 91300000 | 54900000000 | 35900000000000 | 0.5411 | 0.1415 | 0.0040 | 0.0007 | 0.0464 | 0.0056 | 0.1300 | 0.0190 | 0.1950 | 0.0556 | 0.1963 | 0.0999 | 0.1817 | 0.1955 | 0.1300 | 0.1871 | 0.0756 | 0.1906 | 0.0411 | 0.2461 | 0.0000 | 0.0000 | 0.0029 | 0.0015 | 0.0059 | 0.0049 | 0.0305 | 0.0148 | 0.0610 | 0.0473 | 0.1103 | 0.0976 | 0.1139 | 0.0867 | 0.1144 | 0.1114 | 0.5610 | 0.6358 | 0.0032 | 0.0082 | 0.0095 | 0.0148 | 0.0242 | 0.0346 | 0.0621 | 0.0824 | 0.1137 | 0.1466 | 0.1505 | 0.1928 | 0.1232 | 0.1285 | 0.1568 | 0.1450 | 0.3568 | 0.2471 | 0.0007 | 0.0015 | 0.0154 | 0.0308 | 0.0968 | 0.1357 | 0.1086 | 0.1519 | 0.4585 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 122 | 891 | 5327 | 11696 | 148.0 | 43.59 | 217.70 | 199.22 | 99 | 112 | 123 | 132 | 142 | 151 | 163 | 179 | 203 | 0.0892 | 1043 | 1.215 | 95.34 | 38.64 | 1 | 0.0466 | 248 | 0.0014 | 41.30 | 6.881 | 0.2047 | 23789.2 | 4180000 | 807000000 | 172000000000 | 0.4266 | 0.2289 | 0.0000 | 0.0000 | 0.0056 | 0.0000 | 0.0251 | 0.0013 | 0.0471 | 0.0047 | 0.1157 | 0.0325 | 0.1666 | 0.0629 | 0.1649 | 0.0713 | 0.1997 | 0.1120 | 0.2754 | 0.7151 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0038 | 0.0006 | 0.0121 | 0.0008 | 0.0476 | 0.0188 | 0.0784 | 0.0323 | 0.0758 | 0.0298 | 0.1162 | 0.0531 | 0.6657 | 0.8647 | 0.0082 | 0.0150 | 0.0082 | 0.0107 | 0.0245 | 0.0515 | 0.0927 | 0.1180 | 0.1455 | 0.1888 | 0.1936 | 0.1996 | 0.1264 | 0.1245 | 0.1564 | 0.1352 | 0.2445 | 0.1567 | 0.0017 | 0.0038 | 0.0137 | 0.0384 | 0.0970 | 0.1482 | 0.1179 | 0.1521 | 0.4272 | 20 | 42 | 72 | 110 | 157 | 216 | 283 | 375 | 516 | 0.0025 | 101.46 | 7.379 | 0.2318 | 87079.5 | 45700000 | 28000000000 | 19200000000000 | 0.4833 | 0.1693 | 0.0350 | 0.0024 | 0.1038 | 0.0141 | 0.1931 | 0.0587 | 0.1431 | 0.1069 | 0.1600 | 0.1598 | 0.1213 | 0.1625 | 0.1000 | 0.1305 | 0.0781 | 0.1354 | 0.0656 | 0.2298 | 0.0009 | 0.0005 | 0.0017 | 0.0025 | 0.0061 | 0.0045 | 0.0160 | 0.0176 | 0.0575 | 0.0550 | 0.0955 | 0.0812 | 0.0699 | 0.0655 | 0.1043 | 0.0953 | 0.6482 | 0.6780 | 0.0013 | 0.0012 | 0.0039 | 0.0053 | 0.0078 | 0.0112 | 0.0234 | 0.0287 | 0.0793 | 0.0765 | 0.1139 | 0.1255 | 0.0886 | 0.0921 | 0.1219 | 0.1240 | 0.5599 | 0.5353 | 0.0011 | 0.0013 | 0.0071 | 0.0174 | 0.0656 | 0.1025 | 0.0861 | 0.1177 | 0.6012 | |||
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 816 | 393 | 5950 | 11342 | 117.6 | 33.32 | 249.29 | 173.91 | 81 | 90 | 98 | 105 | 112 | 120 | 129 | 141 | 162 | 0.0886 | 1005 | 0.628 | 179.79 | 48.30 | 1 | 0.0987 | 587 | 0.0027 | 14.82 | 6.257 | 0.2986 | 14935.3 | 2060000 | 307000000 | 49700000000 | 0.4437 | 0.2043 | 0.0009 | 0.0002 | 0.0033 | 0.0000 | 0.0082 | 0.0002 | 0.0331 | 0.0046 | 0.0759 | 0.0228 | 0.1588 | 0.0532 | 0.1527 | 0.0566 | 0.1907 | 0.0777 | 0.3764 | 0.7848 | 0.0005 | 0.0002 | 0.0014 | 0.0000 | 0.0036 | 0.0002 | 0.0167 | 0.0016 | 0.0351 | 0.0130 | 0.0689 | 0.0288 | 0.0680 | 0.0227 | 0.0975 | 0.0363 | 0.7084 | 0.8972 | 0.0052 | 0.0056 | 0.0070 | 0.0056 | 0.0235 | 0.0206 | 0.0506 | 0.0882 | 0.0950 | 0.1689 | 0.1578 | 0.1388 | 0.1046 | 0.1107 | 0.1290 | 0.1370 | 0.4272 | 0.3246 | 0.0020 | 0.0051 | 0.0094 | 0.0279 | 0.0822 | 0.1188 | 0.0917 | 0.1200 | 0.5429 | 40 | 81 | 128 | 176 | 225 | 279 | 333 | 394 | 483 | 0.0016 | 78.48 | 7.365 | 0.2033 | 92387.6 | 42200000 | 22200000000 | 13200000000000 | 0.4848 | 0.1839 | 0.0286 | 0.0012 | 0.1297 | 0.0127 | 0.2654 | 0.0476 | 0.1826 | 0.1174 | 0.1568 | 0.1874 | 0.1170 | 0.2093 | 0.0749 | 0.1488 | 0.0314 | 0.1305 | 0.0136 | 0.1451 | 0.0005 | 0.0000 | 0.0003 | 0.0013 | 0.0040 | 0.0026 | 0.0198 | 0.0140 | 0.0727 | 0.0554 | 0.1270 | 0.1033 | 0.1058 | 0.0836 | 0.1312 | 0.1196 | 0.5388 | 0.6202 | 0.0012 | 0.0026 | 0.0065 | 0.0077 | 0.0102 | 0.0148 | 0.0349 | 0.0586 | 0.1118 | 0.1501 | 0.1780 | 0.1978 | 0.1268 | 0.1369 | 0.1581 | 0.1553 | 0.3725 | 0.2761 | 0.0002 | 0.0031 | 0.0062 | 0.0306 | 0.0849 | 0.1491 | 0.1161 | 0.1500 | 0.4598 | |
MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 445 | 885 | 6720 | 10576 | 145.0 | 36.97 | 295.37 | 234.47 | 104 | 115 | 123 | 131 | 139 | 148 | 158 | 172 | 194 | 0.1029 | 1088 | 0.626 | 198.72 | 50.01 | 1 | 0.0999 | 671 | 0.0017 | 31.55 | 6.712 | 0.2250 | 22380.3 | 3690000 | 653000000 | 124000000000 | 0.4622 | 0.1938 | 0.0005 | 0.0000 | 0.0030 | 0.0002 | 0.0103 | 0.0013 | 0.0323 | 0.0038 | 0.0867 | 0.0230 | 0.1608 | 0.0551 | 0.1817 | 0.0633 | 0.1822 | 0.0935 | 0.3425 | 0.7598 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0023 | 0.0009 | 0.0120 | 0.0021 | 0.0362 | 0.0137 | 0.0734 | 0.0334 | 0.0766 | 0.0241 | 0.1038 | 0.0442 | 0.6935 | 0.8815 | 0.0071 | 0.0081 | 0.0063 | 0.0444 | 0.0205 | 0.0282 | 0.0947 | 0.1290 | 0.1539 | 0.1673 | 0.1902 | 0.1714 | 0.1200 | 0.0968 | 0.1350 | 0.1310 | 0.2723 | 0.2238 | 0.0007 | 0.0044 | 0.0119 | 0.0408 | 0.0983 | 0.1353 | 0.1272 | 0.1452 | 0.4362 | 37 | 76 | 126 | 181 | 247 | 316 | 392 | 484 | 624 | 0.0023 | 85.50 | 7.315 | 0.2151 | 142212.0 | 87400000 | 63000000000 | 51000000000000 | 0.5432 | 0.1364 | 0.0279 | 0.0023 | 0.1381 | 0.0113 | 0.2587 | 0.0476 | 0.1904 | 0.1232 | 0.1774 | 0.1886 | 0.1211 | 0.2083 | 0.0551 | 0.1398 | 0.0244 | 0.1359 | 0.0068 | 0.1429 | 0.0004 | 0.0002 | 0.0022 | 0.0026 | 0.0044 | 0.0034 | 0.0196 | 0.0138 | 0.0714 | 0.0585 | 0.1250 | 0.1079 | 0.1052 | 0.0792 | 0.1248 | 0.1135 | 0.5471 | 0.6207 | 0.0022 | 0.0031 | 0.0054 | 0.0083 | 0.0165 | 0.0211 | 0.0326 | 0.0418 | 0.0979 | 0.1017 | 0.1600 | 0.1663 | 0.1128 | 0.1228 | 0.1279 | 0.1459 | 0.4447 | 0.3890 | 0.0009 | 0.0046 | 0.0110 | 0.0265 | 0.0867 | 0.1423 | 0.1125 | 0.1244 | 0.4912 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1158 | 547 | 3628 | 6182 | 70.1 | 18.21 | 293.38 | 247.61 | 48 | 56 | 61 | 65 | 68 | 73 | 77 | 84 | 93 | 0.1234 | 763 | 0.764 | 96.33 | 26.17 | 2 | 0.0714 | 259 | 0.0063 | 7.41 | 5.408 | 0.3836 | 5245.5 | 419586 | 36100000 | 3360000000 | 0.4909 | 0.1773 | 0.0023 | 0.0000 | 0.0055 | 0.0006 | 0.0137 | 0.0022 | 0.0339 | 0.0099 | 0.0870 | 0.0304 | 0.1612 | 0.0565 | 0.1658 | 0.0624 | 0.1557 | 0.1052 | 0.3750 | 0.7327 | 0.0000 | 0.0000 | 0.0003 | 0.0003 | 0.0021 | 0.0006 | 0.0086 | 0.0049 | 0.0429 | 0.0204 | 0.0689 | 0.0357 | 0.0703 | 0.0319 | 0.0998 | 0.0512 | 0.7071 | 0.8550 | 0.0014 | 0.0156 | 0.0205 | 0.0156 | 0.0533 | 0.1172 | 0.0861 | 0.1367 | 0.1516 | 0.1797 | 0.1954 | 0.1680 | 0.1175 | 0.1016 | 0.1434 | 0.0977 | 0.2309 | 0.1680 | 0.0029 | 0.0041 | 0.0140 | 0.0479 | 0.0918 | 0.1350 | 0.1227 | 0.1508 | 0.4307 | 31 | 70 | 122 | 175 | 230 | 293 | 376 | 483 | 655 | 0.0026 | 110.17 | 7.306 | 0.2160 | 147376.0 | 96400000 | 74100000000 | 63400000000000 | 0.5179 | 0.1541 | 0.0174 | 0.0019 | 0.0872 | 0.0087 | 0.1851 | 0.0367 | 0.1986 | 0.0783 | 0.1928 | 0.1522 | 0.1415 | 0.2011 | 0.0688 | 0.1609 | 0.0736 | 0.1542 | 0.0349 | 0.2059 | 0.0013 | 0.0005 | 0.0023 | 0.0022 | 0.0085 | 0.0027 | 0.0214 | 0.0121 | 0.0628 | 0.0486 | 0.0986 | 0.0955 | 0.0832 | 0.0720 | 0.1216 | 0.1055 | 0.6003 | 0.6608 | 0.0015 | 0.0037 | 0.0040 | 0.0086 | 0.0119 | 0.0165 | 0.0308 | 0.0354 | 0.0826 | 0.0886 | 0.1323 | 0.1405 | 0.0930 | 0.1069 | 0.1264 | 0.1497 | 0.5174 | 0.4502 | 0.0012 | 0.0016 | 0.0113 | 0.0311 | 0.0638 | 0.1179 | 0.0973 | 0.1179 | 0.5579 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 634 | 828 | 6200 | 7303 | 203.7 | 43.18 | 209.83 | 149.65 | 154 | 167 | 178 | 188 | 198 | 208 | 221 | 237 | 262 | 0.1191 | 870 | 1.113 | 92.59 | 26.68 | 1 | 0.0353 | 219 | 0.0012 | 41.78 | 7.014 | 0.1838 | 43340.5 | 9650000 | 2250000000 | 547000000000 | 0.4334 | 0.2122 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0031 | 0.0003 | 0.0157 | 0.0007 | 0.0711 | 0.0174 | 0.1256 | 0.0376 | 0.1517 | 0.0398 | 0.1830 | 0.0615 | 0.4490 | 0.8428 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0019 | 0.0002 | 0.0066 | 0.0000 | 0.0335 | 0.0122 | 0.0534 | 0.0229 | 0.0720 | 0.0143 | 0.0964 | 0.0265 | 0.7359 | 0.9239 | 0.0059 | 0.0102 | 0.0088 | 0.0307 | 0.0137 | 0.0648 | 0.0715 | 0.1160 | 0.1538 | 0.1945 | 0.1851 | 0.1672 | 0.1303 | 0.1297 | 0.1538 | 0.1229 | 0.2772 | 0.1638 | 0.0025 | 0.0040 | 0.0087 | 0.0395 | 0.0938 | 0.1242 | 0.1177 | 0.1409 | 0.4687 | 40 | 70 | 103 | 137 | 177 | 225 | 280 | 343 | 426 | 0.0014 | 93.66 | 7.304 | 0.1920 | 66420.4 | 25900000 | 11500000000 | 5580000000000 | 0.5796 | 0.1202 | 0.0390 | 0.0023 | 0.1851 | 0.0148 | 0.2695 | 0.0760 | 0.1802 | 0.1442 | 0.1420 | 0.1832 | 0.1063 | 0.2186 | 0.0446 | 0.1454 | 0.0219 | 0.1134 | 0.0114 | 0.1021 | 0.0005 | 0.0007 | 0.0029 | 0.0009 | 0.0084 | 0.0050 | 0.0260 | 0.0176 | 0.0825 | 0.0686 | 0.1372 | 0.1114 | 0.1075 | 0.0997 | 0.1319 | 0.1233 | 0.5030 | 0.5729 | 0.0019 | 0.0034 | 0.0051 | 0.0059 | 0.0179 | 0.0206 | 0.0451 | 0.0677 | 0.1147 | 0.1290 | 0.1683 | 0.1986 | 0.1306 | 0.1226 | 0.1446 | 0.1466 | 0.3719 | 0.3055 | 0.0003 | 0.0064 | 0.0121 | 0.0359 | 0.0978 | 0.1547 | 0.1134 | 0.1556 | 0.4239 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 991 | 259 | 6417 | 8793 | 106.8 | 27.20 | 230.17 | 178.27 | 75 | 83 | 90 | 97 | 103 | 111 | 119 | 129 | 143 | 0.0945 | 831 | 1.049 | 86.61 | 32.57 | 1 | 0.0376 | 241 | 0.0029 | 14.53 | 6.155 | 0.2937 | 12146.3 | 1470000 | 189000000 | 26000000000 | 0.4126 | 0.2368 | 0.0008 | 0.0000 | 0.0025 | 0.0003 | 0.0124 | 0.0009 | 0.0395 | 0.0028 | 0.1013 | 0.0232 | 0.1836 | 0.0560 | 0.1626 | 0.0640 | 0.1775 | 0.0993 | 0.3197 | 0.7534 | 0.0006 | 0.0000 | 0.0010 | 0.0003 | 0.0037 | 0.0006 | 0.0134 | 0.0005 | 0.0424 | 0.0139 | 0.0779 | 0.0310 | 0.0647 | 0.0240 | 0.0895 | 0.0392 | 0.7067 | 0.8904 | 0.0023 | 0.0180 | 0.0054 | 0.0315 | 0.0161 | 0.0856 | 0.0889 | 0.1464 | 0.1418 | 0.1937 | 0.1916 | 0.1914 | 0.1448 | 0.0766 | 0.1402 | 0.1126 | 0.2690 | 0.1441 | 0.0020 | 0.0051 | 0.0136 | 0.0322 | 0.0770 | 0.1126 | 0.1079 | 0.1228 | 0.5268 | 22 | 53 | 93 | 153 | 208 | 257 | 312 | 379 | 480 | 0.0024 | 67.01 | 7.297 | 0.2596 | 84755.6 | 38600000 | 20300000000 | 11900000000000 | 0.5009 | 0.1509 | 0.0115 | 0.0013 | 0.0850 | 0.0111 | 0.1797 | 0.0293 | 0.1714 | 0.0723 | 0.2027 | 0.1309 | 0.1675 | 0.1982 | 0.1023 | 0.1576 | 0.0588 | 0.1709 | 0.0211 | 0.2285 | 0.0002 | 0.0000 | 0.0019 | 0.0005 | 0.0042 | 0.0025 | 0.0137 | 0.0090 | 0.0529 | 0.0395 | 0.1047 | 0.0857 | 0.0764 | 0.0623 | 0.1081 | 0.0863 | 0.6379 | 0.7142 | 0.0003 | 0.0016 | 0.0046 | 0.0049 | 0.0083 | 0.0178 | 0.0293 | 0.0348 | 0.0788 | 0.1077 | 0.1569 | 0.1814 | 0.1143 | 0.1174 | 0.1359 | 0.1344 | 0.4716 | 0.4000 | 0.0005 | 0.0023 | 0.0055 | 0.0193 | 0.0660 | 0.1225 | 0.0971 | 0.1207 | 0.5661 | |||
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 933 | 214 | 5101 | 5870 | 110.2 | 27.49 | 259.56 | 186.24 | 81 | 88 | 94 | 100 | 106 | 112 | 119 | 129 | 146 | 0.1181 | 693 | 0.954 | 104.01 | 27.86 | 1 | 0.0514 | 262 | 0.0033 | 15.83 | 6.117 | 0.2885 | 12892.3 | 1610000 | 215000000 | 30600000000 | 0.4365 | 0.2174 | 0.0000 | 0.0000 | 0.0034 | 0.0000 | 0.0103 | 0.0002 | 0.0327 | 0.0041 | 0.0791 | 0.0237 | 0.1405 | 0.0507 | 0.1464 | 0.0487 | 0.1803 | 0.0643 | 0.4074 | 0.8083 | 0.0000 | 0.0000 | 0.0017 | 0.0000 | 0.0027 | 0.0000 | 0.0133 | 0.0010 | 0.0360 | 0.0143 | 0.0691 | 0.0261 | 0.0718 | 0.0191 | 0.1049 | 0.0323 | 0.7006 | 0.9072 | 0.0043 | 0.0000 | 0.0076 | 0.0104 | 0.0205 | 0.0286 | 0.0777 | 0.1042 | 0.1295 | 0.1823 | 0.1672 | 0.2031 | 0.1176 | 0.0964 | 0.1316 | 0.1406 | 0.3441 | 0.2344 | 0.0009 | 0.0045 | 0.0190 | 0.0407 | 0.0945 | 0.1392 | 0.1062 | 0.1456 | 0.4494 | 32 | 73 | 127 | 182 | 237 | 290 | 350 | 422 | 519 | 0.0019 | 77.87 | 7.288 | 0.2207 | 102053.0 | 48600000 | 26200000000 | 15400000000000 | 0.5763 | 0.1260 | 0.0142 | 0.0028 | 0.0809 | 0.0120 | 0.1813 | 0.0384 | 0.2018 | 0.0791 | 0.1947 | 0.1512 | 0.1493 | 0.1883 | 0.1084 | 0.1684 | 0.0516 | 0.1489 | 0.0178 | 0.2109 | 0.0003 | 0.0003 | 0.0018 | 0.0013 | 0.0055 | 0.0029 | 0.0160 | 0.0108 | 0.0674 | 0.0567 | 0.1167 | 0.0966 | 0.0890 | 0.0764 | 0.1290 | 0.1066 | 0.5743 | 0.6484 | 0.0014 | 0.0036 | 0.0019 | 0.0006 | 0.0113 | 0.0164 | 0.0386 | 0.0498 | 0.1050 | 0.1343 | 0.1671 | 0.1926 | 0.1266 | 0.1179 | 0.1558 | 0.1422 | 0.3922 | 0.3426 | 0.0000 | 0.0033 | 0.0052 | 0.0298 | 0.0818 | 0.1369 | 0.1153 | 0.1447 | 0.4829 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 456 | 893 | 7298 | 7323 | 187.1 | 41.22 | 216.83 | 133.57 | 140 | 153 | 163 | 172 | 181 | 191 | 203 | 217 | 241 | 0.1269 | 929 | 1.120 | 100.70 | 34.44 | 2 | 0.0340 | 248 | 0.0013 | 39.38 | 6.942 | 0.1916 | 36690.8 | 7560000 | 1640000000 | 376000000000 | 0.4324 | 0.2088 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0047 | 0.0003 | 0.0179 | 0.0010 | 0.0803 | 0.0227 | 0.1350 | 0.0383 | 0.1477 | 0.0424 | 0.1875 | 0.0685 | 0.4263 | 0.8267 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0059 | 0.0001 | 0.0393 | 0.0136 | 0.0647 | 0.0208 | 0.0718 | 0.0167 | 0.1034 | 0.0300 | 0.7137 | 0.9187 | 0.0101 | 0.0100 | 0.0135 | 0.0376 | 0.0262 | 0.0526 | 0.0760 | 0.1153 | 0.1529 | 0.1980 | 0.1782 | 0.1930 | 0.1275 | 0.1454 | 0.1579 | 0.1103 | 0.2576 | 0.1378 | 0.0021 | 0.0043 | 0.0092 | 0.0374 | 0.0860 | 0.1310 | 0.1127 | 0.1396 | 0.4776 | 63 | 92 | 126 | 158 | 191 | 228 | 275 | 332 | 409 | 0.0011 | 78.81 | 7.283 | 0.1845 | 64856.6 | 23800000 | 10100000000 | 4840000000000 | 0.5256 | 0.1334 | 0.0183 | 0.0013 | 0.0889 | 0.0097 | 0.2296 | 0.0405 | 0.1967 | 0.0866 | 0.1778 | 0.1704 | 0.1364 | 0.2228 | 0.0944 | 0.1556 | 0.0384 | 0.1403 | 0.0195 | 0.1729 | 0.0015 | 0.0002 | 0.0025 | 0.0028 | 0.0091 | 0.0054 | 0.0269 | 0.0191 | 0.0793 | 0.0611 | 0.1299 | 0.1025 | 0.1089 | 0.0860 | 0.1316 | 0.1112 | 0.5104 | 0.6118 | 0.0033 | 0.0033 | 0.0066 | 0.0076 | 0.0166 | 0.0239 | 0.0439 | 0.0631 | 0.1159 | 0.1430 | 0.1718 | 0.1816 | 0.1308 | 0.1294 | 0.1320 | 0.1457 | 0.3791 | 0.3023 | 0.0009 | 0.0060 | 0.0160 | 0.0393 | 0.0978 | 0.1494 | 0.1142 | 0.1324 | 0.4439 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 216 | 528 | 5345 | 6687 | 126.2 | 29.45 | 246.37 | 196.30 | 92 | 102 | 109 | 116 | 122 | 129 | 137 | 148 | 166 | 0.1069 | 715 | 0.821 | 98.35 | 24.08 | 1 | 0.0462 | 247 | 0.0025 | 20.42 | 6.327 | 0.2607 | 16786.6 | 2360000 | 350000000 | 54900000000 | 0.4217 | 0.2280 | 0.0006 | 0.0000 | 0.0020 | 0.0002 | 0.0049 | 0.0002 | 0.0260 | 0.0037 | 0.0795 | 0.0242 | 0.1393 | 0.0480 | 0.1549 | 0.0494 | 0.1980 | 0.0730 | 0.3948 | 0.8015 | 0.0002 | 0.0000 | 0.0014 | 0.0002 | 0.0025 | 0.0000 | 0.0114 | 0.0013 | 0.0377 | 0.0144 | 0.0616 | 0.0276 | 0.0705 | 0.0203 | 0.1045 | 0.0325 | 0.7102 | 0.9036 | 0.0065 | 0.0029 | 0.0043 | 0.0324 | 0.0293 | 0.0412 | 0.0759 | 0.1265 | 0.1605 | 0.1765 | 0.1811 | 0.1882 | 0.1215 | 0.1500 | 0.1443 | 0.1412 | 0.2766 | 0.1412 | 0.0037 | 0.0058 | 0.0146 | 0.0379 | 0.0853 | 0.1328 | 0.1087 | 0.1424 | 0.4688 | 29 | 68 | 108 | 156 | 206 | 258 | 323 | 400 | 511 | 0.0020 | 102.03 | 7.263 | 0.2296 | 99223.3 | 51700000 | 32100000000 | 22600000000000 | 0.4373 | 0.2354 | 0.0192 | 0.0026 | 0.0936 | 0.0096 | 0.1554 | 0.0379 | 0.1930 | 0.0889 | 0.1696 | 0.1612 | 0.1637 | 0.1886 | 0.0952 | 0.1468 | 0.0693 | 0.1476 | 0.0409 | 0.2169 | 0.0003 | 0.0010 | 0.0017 | 0.0010 | 0.0063 | 0.0027 | 0.0199 | 0.0129 | 0.0515 | 0.0493 | 0.1085 | 0.0818 | 0.0863 | 0.0592 | 0.1102 | 0.0896 | 0.6153 | 0.7027 | 0.0000 | 0.0000 | 0.0026 | 0.0055 | 0.0110 | 0.0197 | 0.0408 | 0.0466 | 0.0891 | 0.1102 | 0.1414 | 0.1694 | 0.1137 | 0.1190 | 0.1378 | 0.1464 | 0.4636 | 0.3832 | 0.0007 | 0.0028 | 0.0067 | 0.0245 | 0.0823 | 0.1199 | 0.0986 | 0.1341 | 0.5303 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 764 | 823 | 6160 | 9088 | 204.9 | 44.54 | 210.61 | 171.66 | 152 | 168 | 179 | 190 | 200 | 211 | 223 | 239 | 264 | 0.0980 | 891 | 1.013 | 96.21 | 25.02 | 1 | 0.0381 | 235 | 0.0012 | 43.96 | 7.040 | 0.1905 | 43952.7 | 9880000 | 2330000000 | 576000000000 | 0.4516 | 0.2009 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0032 | 0.0000 | 0.0159 | 0.0009 | 0.0737 | 0.0187 | 0.1409 | 0.0415 | 0.1416 | 0.0468 | 0.1792 | 0.0731 | 0.4452 | 0.8191 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0049 | 0.0002 | 0.0318 | 0.0125 | 0.0631 | 0.0233 | 0.0618 | 0.0189 | 0.0953 | 0.0339 | 0.7420 | 0.9113 | 0.0039 | 0.0160 | 0.0106 | 0.0543 | 0.0299 | 0.0607 | 0.0781 | 0.1182 | 0.1408 | 0.1725 | 0.2064 | 0.2013 | 0.1225 | 0.1182 | 0.1524 | 0.1054 | 0.2555 | 0.1534 | 0.0025 | 0.0032 | 0.0104 | 0.0365 | 0.0879 | 0.1397 | 0.1065 | 0.1415 | 0.4718 | 39 | 68 | 97 | 128 | 165 | 210 | 263 | 332 | 440 | 0.0016 | 92.09 | 7.254 | 0.2167 | 73819.8 | 36000000 | 22600000000 | 17500000000000 | 0.5552 | 0.1172 | 0.0288 | 0.0009 | 0.1403 | 0.0040 | 0.2442 | 0.0581 | 0.1735 | 0.1210 | 0.1653 | 0.1922 | 0.1083 | 0.2065 | 0.0802 | 0.1390 | 0.0401 | 0.1287 | 0.0194 | 0.1496 | 0.0002 | 0.0002 | 0.0018 | 0.0009 | 0.0043 | 0.0038 | 0.0235 | 0.0144 | 0.0801 | 0.0642 | 0.1300 | 0.1163 | 0.1023 | 0.0810 | 0.1381 | 0.1164 | 0.5198 | 0.6028 | 0.0014 | 0.0031 | 0.0038 | 0.0031 | 0.0153 | 0.0206 | 0.0400 | 0.0601 | 0.1247 | 0.1250 | 0.1626 | 0.1737 | 0.1107 | 0.1123 | 0.1393 | 0.1368 | 0.4022 | 0.3654 | 0.0003 | 0.0006 | 0.0075 | 0.0304 | 0.1033 | 0.1536 | 0.1133 | 0.1467 | 0.4445 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 359 | 542 | 4621 | 10762 | 146.2 | 33.43 | 222.69 | 177.49 | 107 | 118 | 125 | 134 | 142 | 151 | 161 | 172 | 191 | 0.0783 | 843 | 0.885 | 76.16 | 18.03 | 1 | 0.0390 | 180 | 0.0019 | 23.24 | 6.525 | 0.2373 | 22484.2 | 3640000 | 620000000 | 111000000000 | 0.4346 | 0.2115 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0058 | 0.0002 | 0.0194 | 0.0023 | 0.0890 | 0.0207 | 0.1549 | 0.0458 | 0.1876 | 0.0490 | 0.2146 | 0.0759 | 0.3279 | 0.8061 | 0.0000 | 0.0000 | 0.0005 | 0.0000 | 0.0024 | 0.0002 | 0.0059 | 0.0009 | 0.0386 | 0.0147 | 0.0709 | 0.0249 | 0.0768 | 0.0190 | 0.1183 | 0.0332 | 0.6866 | 0.9071 | 0.0061 | 0.0150 | 0.0207 | 0.0187 | 0.0292 | 0.0487 | 0.0901 | 0.1423 | 0.1681 | 0.1723 | 0.1791 | 0.2247 | 0.1108 | 0.1086 | 0.1462 | 0.1236 | 0.2497 | 0.1461 | 0.0009 | 0.0043 | 0.0080 | 0.0326 | 0.0913 | 0.1456 | 0.1210 | 0.1504 | 0.4459 | 44 | 73 | 105 | 144 | 183 | 226 | 275 | 342 | 445 | 0.0015 | 74.52 | 7.246 | 0.2302 | 81090.3 | 40900000 | 26000000000 | 19500000000000 | 0.4630 | 0.1957 | 0.0142 | 0.0014 | 0.0752 | 0.0062 | 0.1565 | 0.0283 | 0.1896 | 0.0627 | 0.1844 | 0.1479 | 0.1697 | 0.2060 | 0.1092 | 0.1512 | 0.0700 | 0.1579 | 0.0312 | 0.2384 | 0.0009 | 0.0003 | 0.0020 | 0.0012 | 0.0062 | 0.0036 | 0.0222 | 0.0121 | 0.0621 | 0.0464 | 0.1076 | 0.0967 | 0.0994 | 0.0695 | 0.1261 | 0.1058 | 0.5735 | 0.6645 | 0.0015 | 0.0019 | 0.0047 | 0.0070 | 0.0174 | 0.0174 | 0.0375 | 0.0557 | 0.0962 | 0.1161 | 0.1535 | 0.1663 | 0.1125 | 0.1199 | 0.1367 | 0.1389 | 0.4401 | 0.3768 | 0.0007 | 0.0043 | 0.0107 | 0.0285 | 0.0859 | 0.1281 | 0.1071 | 0.1381 | 0.4965 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1207 | 372 | 6747 | 8059 | 84.9 | 22.08 | 226.14 | 174.03 | 59 | 67 | 72 | 77 | 82 | 87 | 94 | 102 | 115 | 0.0973 | 784 | 0.311 | 92.65 | 22.47 | 1 | 0.0539 | 364 | 0.0045 | 9.29 | 5.773 | 0.3415 | 7693.6 | 743325 | 76400000 | 8330000000 | 0.4601 | 0.1955 | 0.0008 | 0.0000 | 0.0035 | 0.0002 | 0.0171 | 0.0032 | 0.0403 | 0.0059 | 0.0875 | 0.0285 | 0.1381 | 0.0496 | 0.1482 | 0.0593 | 0.1825 | 0.0963 | 0.3819 | 0.7571 | 0.0002 | 0.0000 | 0.0006 | 0.0002 | 0.0047 | 0.0008 | 0.0110 | 0.0014 | 0.0359 | 0.0141 | 0.0685 | 0.0318 | 0.0726 | 0.0278 | 0.1047 | 0.0507 | 0.7019 | 0.8732 | 0.0043 | 0.0187 | 0.0100 | 0.0280 | 0.0278 | 0.0392 | 0.0563 | 0.1157 | 0.1069 | 0.1530 | 0.1732 | 0.1549 | 0.1354 | 0.1194 | 0.1468 | 0.1269 | 0.3393 | 0.2444 | 0.0013 | 0.0070 | 0.0152 | 0.0394 | 0.0795 | 0.1166 | 0.0994 | 0.1259 | 0.5157 | 30 | 54 | 86 | 130 | 191 | 253 | 322 | 398 | 487 | 0.0018 | 56.22 | 7.234 | 0.2526 | 81419.7 | 35200000 | 16800000000 | 8580000000000 | 0.4421 | 0.1940 | 0.0106 | 0.0013 | 0.0478 | 0.0071 | 0.1354 | 0.0260 | 0.1726 | 0.0586 | 0.2159 | 0.1525 | 0.1850 | 0.2115 | 0.1062 | 0.1406 | 0.0770 | 0.1560 | 0.0496 | 0.2464 | 0.0002 | 0.0000 | 0.0002 | 0.0011 | 0.0022 | 0.0025 | 0.0077 | 0.0053 | 0.0453 | 0.0374 | 0.0716 | 0.0706 | 0.0573 | 0.0443 | 0.0759 | 0.0693 | 0.7395 | 0.7695 | 0.0000 | 0.0000 | 0.0023 | 0.0032 | 0.0043 | 0.0056 | 0.0149 | 0.0269 | 0.0503 | 0.0622 | 0.0897 | 0.1060 | 0.0659 | 0.0779 | 0.1007 | 0.1212 | 0.6719 | 0.5969 | 0.0003 | 0.0017 | 0.0031 | 0.0136 | 0.0454 | 0.0838 | 0.0532 | 0.0830 | 0.7160 | |||
Hs 578T | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 559 | 386 | 734 | 10113 | 39.1 | 16.71 | 545.35 | 386.84 | 28 | 29 | 30 | 31 | 32 | 34 | 37 | 45 | 64 | 0.0518 | 524 | 0.593 | 209.07 | 60.01 | 2 | 0.9973 | 732 | 0.0308 | 4.90 | 4.259 | 0.5054 | 1809.2 | 103002 | 7120000 | 567000000 | 0.4029 | 0.2328 | 0.0252 | 0.0000 | 0.0540 | 0.0000 | 0.0755 | 0.0000 | 0.1295 | 0.0174 | 0.1403 | 0.0616 | 0.1799 | 0.0585 | 0.1403 | 0.0932 | 0.1475 | 0.0853 | 0.1079 | 0.6840 | 0.0170 | 0.0000 | 0.0365 | 0.0000 | 0.0462 | 0.0000 | 0.0754 | 0.0136 | 0.0730 | 0.0409 | 0.0900 | 0.0368 | 0.0681 | 0.0587 | 0.1095 | 0.0559 | 0.4842 | 0.7940 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0376 | 0.0200 | 0.0752 | 0.1500 | 0.0827 | 0.0400 | 0.0977 | 0.1100 | 0.0752 | 0.1200 | 0.6316 | 0.5600 | 0.0000 | 0.0052 | 0.0103 | 0.0155 | 0.0619 | 0.0825 | 0.0825 | 0.0928 | 0.6495 | 110 | 186 | 267 | 361 | 473 | 591 | 720 | 874 | 1078 | 0.0014 | 42.72 | 7.230 | 0.2482 | 447031.0 | 456000000 | 536000000000 | 698000000000000 | 0.4409 | 0.2151 | 0.0049 | 0.0008 | 0.0213 | 0.0030 | 0.1079 | 0.0134 | 0.1706 | 0.0422 | 0.2262 | 0.1218 | 0.2011 | 0.1874 | 0.1226 | 0.1487 | 0.0823 | 0.1769 | 0.0632 | 0.3059 | 0.0004 | 0.0003 | 0.0013 | 0.0006 | 0.0037 | 0.0034 | 0.0144 | 0.0101 | 0.0397 | 0.0346 | 0.0744 | 0.0570 | 0.0498 | 0.0461 | 0.0699 | 0.0684 | 0.7464 | 0.7795 | 0.0017 | 0.0015 | 0.0017 | 0.0015 | 0.0043 | 0.0070 | 0.0218 | 0.0278 | 0.0519 | 0.0725 | 0.0930 | 0.1147 | 0.0904 | 0.1118 | 0.1106 | 0.1336 | 0.6246 | 0.5296 | 0.0007 | 0.0052 | 0.0059 | 0.0197 | 0.0437 | 0.0749 | 0.0656 | 0.0837 | 0.7007 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 1098 | 245 | 11985 | 25048 | 84.9 | 24.68 | 210.46 | 174.39 | 57 | 66 | 72 | 78 | 83 | 89 | 96 | 104 | 117 | 0.0493 | 1235 | 1.212 | 170.77 | 60.46 | 3 | 0.0339 | 406 | 0.0035 | 11.99 | 6.022 | 0.3238 | 7822.1 | 773291 | 81600000 | 9180000000 | 0.4646 | 0.2016 | 0.0015 | 0.0001 | 0.0035 | 0.0002 | 0.0189 | 0.0013 | 0.0497 | 0.0060 | 0.0986 | 0.0268 | 0.1577 | 0.0599 | 0.1701 | 0.0693 | 0.1916 | 0.1035 | 0.3083 | 0.7329 | 0.0005 | 0.0000 | 0.0011 | 0.0001 | 0.0039 | 0.0001 | 0.0150 | 0.0019 | 0.0339 | 0.0136 | 0.0662 | 0.0303 | 0.0676 | 0.0255 | 0.0968 | 0.0435 | 0.7150 | 0.8851 | 0.0033 | 0.0121 | 0.0080 | 0.0260 | 0.0256 | 0.0419 | 0.0756 | 0.1200 | 0.1388 | 0.1842 | 0.1465 | 0.1777 | 0.1385 | 0.1284 | 0.1600 | 0.1265 | 0.3036 | 0.1833 | 0.0009 | 0.0050 | 0.0135 | 0.0414 | 0.0740 | 0.1119 | 0.1069 | 0.1367 | 0.5097 | 27 | 50 | 85 | 129 | 174 | 220 | 274 | 342 | 444 | 0.0030 | 74.43 | 7.191 | 0.2347 | 74701.9 | 35300000 | 20500000000 | 14000000000000 | 0.4914 | 0.1942 | 0.0341 | 0.0005 | 0.1480 | 0.0067 | 0.2568 | 0.0741 | 0.1712 | 0.1263 | 0.1455 | 0.1772 | 0.1169 | 0.1937 | 0.0654 | 0.1449 | 0.0389 | 0.1300 | 0.0232 | 0.1465 | 0.0003 | 0.0001 | 0.0016 | 0.0005 | 0.0037 | 0.0012 | 0.0153 | 0.0094 | 0.0721 | 0.0542 | 0.1302 | 0.1070 | 0.0998 | 0.0805 | 0.1378 | 0.1181 | 0.5392 | 0.6290 | 0.0009 | 0.0021 | 0.0040 | 0.0065 | 0.0122 | 0.0178 | 0.0377 | 0.0512 | 0.1055 | 0.1206 | 0.1719 | 0.1793 | 0.1135 | 0.1149 | 0.1437 | 0.1477 | 0.4105 | 0.3599 | 0.0007 | 0.0020 | 0.0080 | 0.0239 | 0.0873 | 0.1563 | 0.1162 | 0.1382 | 0.4675 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 799 | 497 | 16816 | 24748 | 122.3 | 34.96 | 236.76 | 206.30 | 82 | 94 | 102 | 110 | 118 | 126 | 136 | 149 | 168 | 0.0650 | 1609 | 1.118 | 72.20 | 25.02 | 3 | 0.0108 | 181 | 0.0021 | 18.82 | 6.539 | 0.2763 | 16190.9 | 2320000 | 358000000 | 60000000000 | 0.4389 | 0.2098 | 0.0010 | 0.0001 | 0.0025 | 0.0003 | 0.0091 | 0.0014 | 0.0328 | 0.0040 | 0.0891 | 0.0250 | 0.1521 | 0.0565 | 0.1545 | 0.0597 | 0.1758 | 0.0901 | 0.3831 | 0.7630 | 0.0004 | 0.0001 | 0.0005 | 0.0000 | 0.0026 | 0.0002 | 0.0095 | 0.0013 | 0.0356 | 0.0130 | 0.0650 | 0.0262 | 0.0618 | 0.0238 | 0.0849 | 0.0395 | 0.7396 | 0.8959 | 0.0031 | 0.0096 | 0.0075 | 0.0071 | 0.0173 | 0.0199 | 0.0537 | 0.1065 | 0.1221 | 0.1508 | 0.1553 | 0.2060 | 0.1205 | 0.1232 | 0.1477 | 0.1521 | 0.3728 | 0.2246 | 0.0013 | 0.0031 | 0.0088 | 0.0298 | 0.0749 | 0.1135 | 0.0977 | 0.1296 | 0.5413 | 21 | 45 | 86 | 134 | 187 | 246 | 312 | 397 | 532 | 0.0053 | 78.87 | 7.190 | 0.2785 | 98609.0 | 53500000 | 34300000000 | 24800000000000 | 0.5106 | 0.1669 | 0.0256 | 0.0012 | 0.1110 | 0.0083 | 0.2322 | 0.0422 | 0.1927 | 0.1005 | 0.1604 | 0.1805 | 0.1290 | 0.2104 | 0.0825 | 0.1584 | 0.0439 | 0.1366 | 0.0227 | 0.1620 | 0.0004 | 0.0002 | 0.0009 | 0.0012 | 0.0050 | 0.0019 | 0.0154 | 0.0099 | 0.0609 | 0.0492 | 0.1064 | 0.0949 | 0.0889 | 0.0752 | 0.1192 | 0.1063 | 0.6028 | 0.6612 | 0.0004 | 0.0013 | 0.0032 | 0.0039 | 0.0100 | 0.0142 | 0.0294 | 0.0412 | 0.0896 | 0.1025 | 0.1454 | 0.1529 | 0.1084 | 0.1139 | 0.1346 | 0.1366 | 0.4791 | 0.4335 | 0.0001 | 0.0020 | 0.0079 | 0.0209 | 0.0743 | 0.1266 | 0.1001 | 0.1318 | 0.5361 | |
MCF 10A | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 933 | 123 | 15895 | 25256 | 160.6 | 49.99 | 222.36 | 201.78 | 108 | 123 | 135 | 145 | 155 | 167 | 180 | 197 | 224 | 0.0522 | 1319 | 1.013 | 68.60 | 26.63 | 1 | 0.0118 | 188 | 0.0011 | 38.56 | 7.182 | 0.2007 | 28277.2 | 5410000 | 1120000000 | 250000000000 | 0.4469 | 0.2019 | 0.0004 | 0.0000 | 0.0020 | 0.0000 | 0.0077 | 0.0004 | 0.0316 | 0.0036 | 0.1026 | 0.0245 | 0.1744 | 0.0573 | 0.1683 | 0.0626 | 0.1924 | 0.0950 | 0.3207 | 0.7567 | 0.0002 | 0.0000 | 0.0008 | 0.0000 | 0.0020 | 0.0001 | 0.0095 | 0.0013 | 0.0356 | 0.0107 | 0.0680 | 0.0249 | 0.0660 | 0.0239 | 0.0986 | 0.0414 | 0.7192 | 0.8976 | 0.0038 | 0.0039 | 0.0105 | 0.0143 | 0.0212 | 0.0306 | 0.0646 | 0.0971 | 0.1280 | 0.1519 | 0.1664 | 0.1956 | 0.1271 | 0.1167 | 0.1414 | 0.1402 | 0.3371 | 0.2497 | 0.0010 | 0.0033 | 0.0088 | 0.0321 | 0.0763 | 0.1269 | 0.1097 | 0.1304 | 0.5115 | 26 | 46 | 75 | 111 | 161 | 221 | 294 | 379 | 507 | 0.0037 | 85.09 | 7.177 | 0.2606 | 90156.2 | 49000000 | 32300000000 | 24700000000000 | 0.5277 | 0.1518 | 0.0405 | 0.0017 | 0.1859 | 0.0114 | 0.2913 | 0.0812 | 0.1595 | 0.1431 | 0.1289 | 0.2051 | 0.0931 | 0.1986 | 0.0540 | 0.1320 | 0.0300 | 0.1078 | 0.0167 | 0.1190 | 0.0003 | 0.0003 | 0.0017 | 0.0005 | 0.0033 | 0.0024 | 0.0137 | 0.0100 | 0.0734 | 0.0561 | 0.1231 | 0.1010 | 0.0947 | 0.0796 | 0.1369 | 0.1199 | 0.5529 | 0.6302 | 0.0009 | 0.0011 | 0.0033 | 0.0060 | 0.0084 | 0.0108 | 0.0290 | 0.0412 | 0.1013 | 0.1114 | 0.1586 | 0.1680 | 0.1119 | 0.1173 | 0.1427 | 0.1435 | 0.4438 | 0.4007 | 0.0005 | 0.0008 | 0.0048 | 0.0220 | 0.0840 | 0.1483 | 0.1014 | 0.1428 | 0.4955 | |
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 203 | 497 | 8616 | 14575 | 174.6 | 44.13 | 171.91 | 149.45 | 122 | 138 | 150 | 161 | 171 | 181 | 192 | 207 | 232 | 0.0673 | 981 | 1.044 | 125.32 | 34.48 | 1 | 0.0331 | 285 | 0.0012 | 38.52 | 7.056 | 0.1977 | 32427.2 | 6400000 | 1340000000 | 300000000000 | 0.4569 | 0.1989 | 0.0000 | 0.0000 | 0.0017 | 0.0001 | 0.0078 | 0.0003 | 0.0287 | 0.0031 | 0.0888 | 0.0227 | 0.1586 | 0.0483 | 0.1617 | 0.0556 | 0.1808 | 0.0817 | 0.3720 | 0.7881 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0011 | 0.0383 | 0.0140 | 0.0683 | 0.0253 | 0.0693 | 0.0240 | 0.0973 | 0.0396 | 0.7154 | 0.8960 | 0.0043 | 0.0068 | 0.0129 | 0.0307 | 0.0302 | 0.0341 | 0.0851 | 0.1022 | 0.1424 | 0.1959 | 0.1763 | 0.1959 | 0.1128 | 0.1141 | 0.1375 | 0.1210 | 0.2984 | 0.1993 | 0.0015 | 0.0050 | 0.0118 | 0.0350 | 0.0866 | 0.1316 | 0.1178 | 0.1480 | 0.4626 | 22 | 43 | 68 | 99 | 135 | 170 | 218 | 279 | 376 | 0.0026 | 76.94 | 7.156 | 0.2520 | 51884.8 | 21400000 | 11000000000 | 6610000000000 | 0.4445 | 0.1894 | 0.0210 | 0.0006 | 0.0998 | 0.0058 | 0.1884 | 0.0378 | 0.1768 | 0.0812 | 0.1748 | 0.1518 | 0.1509 | 0.1963 | 0.0944 | 0.1541 | 0.0536 | 0.1491 | 0.0404 | 0.2232 | 0.0008 | 0.0002 | 0.0013 | 0.0005 | 0.0043 | 0.0019 | 0.0145 | 0.0096 | 0.0545 | 0.0413 | 0.1088 | 0.0813 | 0.0850 | 0.0660 | 0.1138 | 0.0944 | 0.6169 | 0.7048 | 0.0008 | 0.0011 | 0.0042 | 0.0066 | 0.0085 | 0.0130 | 0.0307 | 0.0414 | 0.0827 | 0.0900 | 0.1433 | 0.1572 | 0.1056 | 0.1118 | 0.1272 | 0.1359 | 0.4970 | 0.4431 | 0.0005 | 0.0029 | 0.0095 | 0.0225 | 0.0731 | 0.1165 | 0.1001 | 0.1229 | 0.5519 | |||
MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 293 | 609 | 8337 | 19608 | 101.9 | 24.16 | 175.88 | 142.47 | 73 | 81 | 88 | 94 | 100 | 105 | 112 | 120 | 133 | 0.0523 | 1025 | 1.074 | 109.56 | 38.12 | 1 | 0.0356 | 297 | 0.0033 | 13.03 | 6.018 | 0.3011 | 10963.8 | 1250000 | 150000000 | 19200000000 | 0.4490 | 0.2070 | 0.0004 | 0.0001 | 0.0023 | 0.0001 | 0.0097 | 0.0004 | 0.0284 | 0.0036 | 0.0817 | 0.0181 | 0.1470 | 0.0410 | 0.1702 | 0.0513 | 0.1762 | 0.0783 | 0.3842 | 0.8070 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0032 | 0.0002 | 0.0086 | 0.0011 | 0.0365 | 0.0115 | 0.0679 | 0.0245 | 0.0709 | 0.0208 | 0.1034 | 0.0398 | 0.7091 | 0.9020 | 0.0034 | 0.0064 | 0.0135 | 0.0451 | 0.0310 | 0.0579 | 0.1018 | 0.1373 | 0.1415 | 0.1803 | 0.1894 | 0.1717 | 0.1240 | 0.0880 | 0.1388 | 0.1652 | 0.2567 | 0.1481 | 0.0010 | 0.0026 | 0.0126 | 0.0419 | 0.0856 | 0.1309 | 0.1186 | 0.1404 | 0.4663 | 19 | 44 | 74 | 106 | 143 | 186 | 235 | 291 | 376 | 0.0029 | 66.47 | 7.155 | 0.2685 | 51228.7 | 19100000 | 8380000000 | 4150000000000 | 0.4441 | 0.1782 | 0.0134 | 0.0030 | 0.0694 | 0.0074 | 0.1927 | 0.0268 | 0.1717 | 0.0701 | 0.1818 | 0.1554 | 0.1490 | 0.1966 | 0.0920 | 0.1467 | 0.0742 | 0.1533 | 0.0557 | 0.2406 | 0.0008 | 0.0005 | 0.0013 | 0.0013 | 0.0030 | 0.0031 | 0.0128 | 0.0102 | 0.0442 | 0.0384 | 0.0810 | 0.0621 | 0.0713 | 0.0562 | 0.1002 | 0.0808 | 0.6853 | 0.7475 | 0.0015 | 0.0011 | 0.0021 | 0.0051 | 0.0067 | 0.0130 | 0.0204 | 0.0276 | 0.0725 | 0.0848 | 0.1212 | 0.1448 | 0.1025 | 0.1133 | 0.1303 | 0.1466 | 0.5429 | 0.4637 | 0.0005 | 0.0020 | 0.0054 | 0.0154 | 0.0553 | 0.1015 | 0.0850 | 0.1150 | 0.6199 | |||
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 320 | 667 | 5012 | 4003 | 144.6 | 31.00 | 256.96 | 210.61 | 110 | 119 | 126 | 133 | 139 | 146 | 155 | 168 | 187 | 0.1699 | 680 | 1.061 | 130.67 | 36.72 | 1 | 0.0599 | 300 | 0.0023 | 22.41 | 6.404 | 0.2450 | 21873.6 | 3470000 | 577000000 | 101000000000 | 0.4357 | 0.2084 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0059 | 0.0000 | 0.0223 | 0.0013 | 0.0711 | 0.0189 | 0.1355 | 0.0456 | 0.1443 | 0.0439 | 0.1875 | 0.0634 | 0.4320 | 0.8269 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0028 | 0.0000 | 0.0083 | 0.0004 | 0.0355 | 0.0130 | 0.0649 | 0.0252 | 0.0675 | 0.0144 | 0.0966 | 0.0244 | 0.7237 | 0.9225 | 0.0073 | 0.0036 | 0.0158 | 0.0144 | 0.0280 | 0.0758 | 0.0767 | 0.1516 | 0.1571 | 0.1913 | 0.1705 | 0.1733 | 0.1255 | 0.1264 | 0.1437 | 0.1155 | 0.2753 | 0.1480 | 0.0038 | 0.0080 | 0.0127 | 0.0363 | 0.0930 | 0.1303 | 0.1085 | 0.1567 | 0.4507 | 33 | 63 | 100 | 155 | 208 | 265 | 333 | 424 | 568 | 0.0020 | 118.54 | 7.148 | 0.2176 | 110371.0 | 60900000 | 39200000000 | 28100000000000 | 0.4840 | 0.1833 | 0.0323 | 0.0038 | 0.1232 | 0.0212 | 0.2097 | 0.0613 | 0.2097 | 0.1272 | 0.1730 | 0.1779 | 0.1510 | 0.2059 | 0.0587 | 0.1476 | 0.0293 | 0.1272 | 0.0132 | 0.1279 | 0.0005 | 0.0000 | 0.0055 | 0.0033 | 0.0099 | 0.0087 | 0.0307 | 0.0229 | 0.0823 | 0.0715 | 0.1368 | 0.1227 | 0.1011 | 0.0932 | 0.1293 | 0.1165 | 0.5040 | 0.5611 | 0.0007 | 0.0055 | 0.0045 | 0.0028 | 0.0112 | 0.0148 | 0.0389 | 0.0572 | 0.1243 | 0.1210 | 0.1534 | 0.1681 | 0.1213 | 0.1385 | 0.1445 | 0.1376 | 0.4012 | 0.3546 | 0.0030 | 0.0066 | 0.0156 | 0.0361 | 0.0968 | 0.1437 | 0.1203 | 0.1371 | 0.4408 | |
MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 659 | 414 | 3454 | 6251 | 174.4 | 39.87 | 242.89 | 154.32 | 131 | 143 | 152 | 159 | 167 | 177 | 189 | 204 | 226 | 0.1125 | 703 | 1.107 | 91.24 | 26.63 | 1 | 0.0617 | 213 | 0.0019 | 25.62 | 6.561 | 0.2385 | 32018.5 | 6210000 | 1280000000 | 278000000000 | 0.4520 | 0.2052 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0088 | 0.0006 | 0.0206 | 0.0022 | 0.0697 | 0.0235 | 0.1434 | 0.0423 | 0.1298 | 0.0346 | 0.1684 | 0.0676 | 0.4579 | 0.8289 | 0.0003 | 0.0000 | 0.0000 | 0.0000 | 0.0017 | 0.0003 | 0.0052 | 0.0003 | 0.0351 | 0.0160 | 0.0762 | 0.0274 | 0.0616 | 0.0189 | 0.1043 | 0.0335 | 0.7155 | 0.9036 | 0.0017 | 0.0154 | 0.0134 | 0.0205 | 0.0185 | 0.0308 | 0.0487 | 0.1026 | 0.1546 | 0.1231 | 0.1748 | 0.1846 | 0.1294 | 0.1538 | 0.1429 | 0.0923 | 0.3160 | 0.2769 | 0.0007 | 0.0033 | 0.0080 | 0.0361 | 0.0916 | 0.1424 | 0.0989 | 0.1404 | 0.4786 | 79 | 111 | 142 | 170 | 206 | 251 | 299 | 360 | 457 | 0.0013 | 68.96 | 7.135 | 0.2323 | 82803.2 | 35900000 | 18500000000 | 10900000000000 | 0.5283 | 0.1292 | 0.0088 | 0.0007 | 0.0739 | 0.0045 | 0.1684 | 0.0182 | 0.1611 | 0.0636 | 0.1859 | 0.1374 | 0.1720 | 0.2049 | 0.1061 | 0.1528 | 0.0820 | 0.1545 | 0.0417 | 0.2633 | 0.0003 | 0.0002 | 0.0027 | 0.0005 | 0.0066 | 0.0040 | 0.0217 | 0.0160 | 0.0714 | 0.0488 | 0.1042 | 0.0905 | 0.0819 | 0.0726 | 0.1153 | 0.1014 | 0.5959 | 0.6660 | 0.0041 | 0.0042 | 0.0051 | 0.0035 | 0.0128 | 0.0229 | 0.0389 | 0.0660 | 0.1064 | 0.1313 | 0.1529 | 0.1771 | 0.1233 | 0.1188 | 0.1483 | 0.1465 | 0.4082 | 0.3299 | 0.0004 | 0.0031 | 0.0100 | 0.0268 | 0.0824 | 0.1234 | 0.1031 | 0.1388 | 0.5121 |