Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)
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| Cell | Small Molecule | GR50 | GRmax | GR_AOC | GEC50 | GRinf | GR Hill Coefficient | GR r2 | pval_GR |
|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | AZD5363 | inf | 1.8797 | -0.1143 | 0.0000 | 1.0000 | 0.0100 | -0.2534 | 1.0 |
| HCC70 | Rucaparib | inf | 1.1144 | -0.0414 | 0.0000 | 1.0000 | 0.0100 | -0.1078 | 1.0 |
| MDA-MB-231 | SHP099 | inf | 0.9470 | -0.0146 | 0.0000 | 1.0000 | 0.0100 | -0.0002 | 0.198394332856 |
| HCC1806 | SHP099 | inf | 0.9525 | -0.0087 | 0.0000 | 1.0000 | 0.0100 | -0.0671 | 0.950463130981 |
| MDA-MB-436 | Ribociclib | inf | 0.9493 | -0.0090 | 0.0000 | 1.0000 | 0.0100 | -0.0149 | 0.928505437 |
| CAL-120 | AZD6738 | inf | 0.7588 | -0.1771 | 0.0000 | 1.0000 | 0.0100 | -1.1414 | 0.170552683 |
| MDA-MB-231 | AZD5363 | inf | 1.0802 | -0.0194 | 0.0000 | 1.0000 | 0.0100 | -0.2298 | 1.0 |
| HCC1428 | AZD6738 | inf | 0.5583 | -0.2743 | 0.0000 | 1.0000 | 0.0100 | -0.1317 | 0.820290357 |
| T47D | AZD6738 | inf | 0.6619 | -0.2131 | 0.0000 | 1.0000 | 0.0100 | -0.9822 | 0.211726496 |
| HCC70 | Ribociclib | inf | 1.0564 | -0.0040 | 0.0000 | 1.0000 | 0.0100 | -0.1699 | 1.0 |
| MDA-MB-436 | SHP099 | inf | 0.8419 | -0.0182 | 0.0000 | 0.9962 | 0.0100 | 0.0000 | 0.527646554 |
| CAMA-1 | GSK2334470 | inf | 0.6437 | -0.0125 | 0.0000 | 0.9959 | 0.0100 | 0.0000 | 0.05607765 |
| HCC1937 | Ribociclib | inf | 0.9905 | -0.0141 | 0.0000 | 0.9898 | 0.0100 | 0.0000 | 1.0 |
| BT-549 | Ribociclib | inf | 0.9258 | 0.0097 | 0.0000 | 0.9885 | 0.0100 | 0.0000 | 0.489440623384 |
| SK-BR-3 | SHP099 | inf | 0.9987 | 0.0260 | 0.0000 | 0.9879 | 0.0100 | 0.0000 | 1.0 |
| BT-20 | SHP099 | inf | 0.8790 | 0.0132 | 0.0000 | 0.9876 | 0.0100 | 0.0000 | 0.0930371400466 |
| T47D | SHP099 | inf | 0.6931 | -0.0080 | 0.0000 | 0.9839 | 0.0100 | 0.0000 | 0.180531821 |
| MDA-MB-468 | Ribociclib | inf | 0.7972 | 0.0091 | 0.0000 | 0.9779 | 0.0100 | 0.0000 | 1.0 |
| CAL-51 | SHP099 | inf | 0.8600 | 0.0220 | 0.0000 | 0.9665 | 0.0100 | 0.0000 | 1.0 |
| MCF7 | SHP099 | inf | 0.8331 | 0.0289 | 0.0000 | 0.9643 | 0.0100 | 0.0000 | 0.073472433 |
| AU565 | SHP099 | inf | 0.9751 | 0.0242 | 0.0000 | 0.9633 | 0.0100 | 0.0000 | 1.0 |
| BT-549 | Rucaparib | inf | 0.8808 | 0.0404 | 0.0000 | 0.9550 | 0.0100 | 0.0000 | 1.0 |
| HCC1419 | SHP099 | inf | 0.7338 | 0.0420 | 0.0000 | 0.9489 | 0.0100 | 0.0000 | 0.203508371 |
| HCC1419 | Rucaparib | inf | 0.8069 | 0.0539 | 0.0000 | 0.9485 | 0.0100 | 0.0000 | 0.337916631 |
| MDA-MB-157 | AZD5363 | inf | 0.6671 | 0.0508 | 0.0000 | 0.9480 | 0.0100 | 0.0000 | 0.135243927 |