Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)
Data Columns
Download: Excel (XLSX), Comma-separated (CSV)
- 10 Data Columns
| Name | Description | Display Name | Data Type | Unit | Precision | Readout Type | Replicate | Comments |
|---|---|---|---|---|---|---|---|---|
| cell | Cell reagent | Cell | cell | |||||
| smallMolecule | Small molecule perturbagen | Small Molecule | small_molecule | |||||
| gR50 | Small molecule concentration in uM at which GR(c)=0.5 | GR50 | Text | |||||
| gRmax | Normalized growth inhibition rate at the highest tested concentration | GRmax | Numeric | 4 | ||||
| gRAOC | Integral of GR(c) over the range of concentrations tested | GR_AOC | Numeric | 4 | ||||
| gEC50 | Small molecule concentration in uM that results in 50% efficacy | GEC50 | Numeric | 4 | ||||
| gRinf | Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the dose-response data | GRinf | Numeric | 4 | ||||
| gRHillCoefficient | Maximal slope of the dose-response curve | GR Hill Coefficient | Numeric | 4 | ||||
| gRR2 | r^2 for the sigmoidal curve fit to the dose-response data | GR r2 | Numeric | 4 | ||||
| pvalGR | Result of F-test for significance of fit | pval_GR | Text |
- 10 Data Columns