Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
MDA-MB-157 Rucaparib
1.111762287
 0.0267 0.3310 48.4687 -1.0000 0.2910 0.5210
0.000101022
HCC1419 AZD5363
51.76366593
 0.5451 0.2255 1.6243 0.3603 0.3683 0.5133
0.000123219
CAL-85-1 RO-3306
6.045627864
 -0.3140 0.2213 9.4578 -1.0000 2.4550 0.5125
0.000125886
MCF7 Rucaparib
20.52571528
 0.5466 0.0691 95.2231 -1.0000 0.7159 0.5083
0.000140012
HCC1937 AZD2014
0.030181855
 0.3561 0.4941 0.0005 0.3576 0.3088 0.5080
0.00014109
CAMA-1 LY3023414
4.27e-05
 -0.5001 0.9375 0.0004 -0.2985 0.2143 0.5057
0.00014946
HCC1143 GSK2334470
438.6004495
 0.6788 0.0824 1000.0000 -0.1385 0.2967 0.5027
0.000161396
MCF 10A GSK2334470
15.0731115613
 0.8830 -0.0129 18.7770 -1.0000 5.0000 0.4636
0.000172093714918
MDA-MB-361 Senexin B
1.759420996
 0.3235 0.2847 157.3873 -1.0000 0.2445 0.4951
0.000194933
HCC1395 LY3023414
0.006658349
 -0.1896 0.6194 2.1680 -0.4984 0.1195 0.4950
0.000195378
HCC1428 AZD2014
2.19e-05
 -0.5555 1.2048 0.0005 -0.5838 0.2503 0.4940
0.000200146
HCC1806 Senexin B
inf
 0.8083 0.1042 0.1453 0.7979 0.4002 0.4857
0.000245355132328
MDA-MB-231 Rucaparib
31.9983825044
 0.5482 0.0971 279.5298 -1.0000 0.5069 0.4838
0.000257239637118
HCC1395 AZD2014
0.010334257
 0.1983 0.5546 0.0017 0.1495 0.1950 0.4827
0.000264203
CAL-120 AZD5363
51.38789856
 0.7988 0.0266 243.4579 -1.0000 0.7063 0.4791
0.0002881
HCC70 Senexin B
16.531300381
 0.4078 0.2194 1000.0000 -0.7732 0.2278 0.4788
0.000290238214042
MDA-MB-361 Ribociclib
0.00037253
 0.1935 0.7764 0.0005 -0.0324 0.2292 0.4761
0.000309356
HCC1428 MK 1775
4.367124658
 -0.4009 0.1027 7.4399 -1.0000 2.0621 0.4706
0.000352941
CAL-51 Ulixertinib
20.08181132
 0.7439 0.0569 48.1868 -0.9997 1.2549 0.4674
0.000380369
HCC38 AZD5363
643.6614856
 0.6677 0.0823 596.8802 0.0105 0.2802 0.4663
0.000390093
HCC1395 Rucaparib
0.937296958
 0.1322 0.4493 681.8335 -1.0000 0.1667 0.4632
0.000419592
HCC1937 AZD6738
7.75547782
 0.2590 -0.1086 19.3707 -0.9926 1.1948 0.4429
0.00046323
CAL-120 GSK2334470
4306.150401
 0.7693 0.0812 1000.0000 0.1525 0.2492 0.4548
0.000509344
MDA-MB-436 Rucaparib
0.828754457
 0.1932 0.4025 792.8667 -0.7731 0.1362 0.4480
0.00059396
MDA-MB-157 AZD6738
8.215702739
 -0.0514 -0.2134 10.2346 -1.0000 5.0000 0.3830
0.000671245
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