Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 2 of 2: GR metrics. - Dataset - HMS LINCS Database

Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 2 of 2: GR metrics. - Dataset (ID:20367)

Download: Excel (XLSX), Comma-separated (CSV)

Filter results: >>>>

<
<<
Previous
Page 1 of 3
Next
>>
>
1 to 25 of 71 records
per page:

Cell line	Drug name	Experimental replicate	Curve type (GR values)	Curve type (relative cell counts)	Experiment name	Number of concentrations	Cell doublings (DMSO control)	GR50	GRmax	GR_AOC	GEC50	GRinf	Hill slope (GR values)	R-squared curve fit (GR values)	P-value curve fit (GR values)	IC50	Emax	AUC	EC50	Einf	Hill slope (relative cell counts)	R-squared curve fit (relative cell counts)	P-value curve fit (relative cell counts)
HCC70	AZD8055	2	sigmoid	sigmoid	HCC70 AZD8055 0 2	9	1.573	0.029	-0.0375	0.612	0.0272	0.0241	0.792	0.972	3.37e-27	0.0959	0.317	0.576	0.0216	0.35	0.808	0.974	9.92e-28
HCC70	QL-XII-108	2	sigmoid	sigmoid	HCC70 QL-XII-108 0 2	9	1.573	1.64	0.0651	0.189	1.78	-0.0491	1.11	0.948	1.42e-22	3.36	0.371	0.867	1.34	0.336	1.2	0.936	4.76e-21
HCC1806	QL-XII-108	2	sigmoid	sigmoid	HCC1806 QL-XII-108 0 2	9	2.714	6.59	0.385	0.105	5.93	0.0605	1.22	0.87	9.22e-16	5.58	0.369	0.88	4.06	0.163	1.24	0.847	1.36e-14
HCC70	Torin1	3	sigmoid	sigmoid	HCC70 Torin1 0 3	9	1.750	0.0678	-0.133	0.547	0.0833	-0.0781	0.706	0.967	3.43e-25	0.133	0.232	0.596	0.0487	0.284	0.833	0.971	4.17e-26
HCC70	AZD8055	1	sigmoid	sigmoid	HCC70 AZD8055 0 1	9	1.598	0.0382	0.0624	0.564	0.0292	0.0882	0.722	0.969	1.75e-26	0.158	0.364	0.601	0.0229	0.379	0.734	0.965	1.44e-25
HCC70	AZD8055	3	sigmoid	sigmoid	HCC70 AZD8055 0 3	9	1.750	0.0456	0.0533	0.54	0.0343	0.105	0.837	0.979	2.64e-29	0.109	0.326	0.593	0.026	0.359	0.885	0.98	1.62e-29
HCC70	QL-XII-108	1	sigmoid	sigmoid	HCC70 QL-XII-108 0 1	9	1.598	1.64	0.0903	0.226	2.06	-0.115	0.914	0.963	5.57e-25	3.65	0.379	0.836	1.5	0.287	0.962	0.954	1.98e-23
HCC1806	Torin1	2	sigmoid	sigmoid	HCC1806 Torin1 0 2	9	2.714	0.669	0.197	0.315	0.434	0.115	0.604	0.978	7.13e-29	0.411	0.249	0.661	0.161	0.243	0.708	0.978	9.2e-29
HCC70	QL-XII-108	3	sigmoid	sigmoid	HCC70 QL-XII-108 0 3	9	1.750	1.72	0.15	0.238	2.29	-0.122	0.763	0.951	5.13e-23	3.53	0.38	0.813	1.52	0.245	0.796	0.937	3.73e-21
HCC70	Torin1	1	sigmoid	sigmoid	HCC70 Torin1 0 1	9	1.598	0.061	-0.147	0.573	0.0884	-0.134	0.64	0.954	1.68e-23	0.182	0.256	0.601	0.057	0.275	0.684	0.957	6.27e-24
HCC1806	Torin1	3	sigmoid	sigmoid	HCC1806 Torin1 0 3	9	2.697	0.393	0.144	0.339	0.25	0.145	0.753	0.972	4.9e-27	0.243	0.222	0.648	0.112	0.264	0.964	0.972	5.22e-27
HCC1806	Torin1	1	sigmoid	sigmoid	HCC1806 Torin1 0 1	9	2.619	0.515	0.179	0.326	0.302	0.148	0.662	0.971	9.22e-27	0.347	0.251	0.66	0.129	0.272	0.796	0.975	8.08e-28
HCC1806	QL-XII-108	3	sigmoid	sigmoid	HCC1806 QL-XII-108 0 3	9	2.697	4.76	0.208	0.11	5.85	-0.166	1.39	0.964	2.49e-25	4.23	0.262	0.882	3.69	0.0906	1.46	0.97	1.09e-26
HCC70	QL-XII-61	2	sigmoid	sigmoid	HCC70 QL-XII-61 0 2	9	1.573	4.5	0.179	0.0498	4.14	0.169	5.0	0.928	3.35e-20	5.98	0.436	0.967	4.03	0.43	5.0	0.913	1.01e-18
HCC1806	QL-XII-61	3	sigmoid	sigmoid	HCC1806 QL-XII-61 0 3	9	2.697	5.77	0.315	0.0462	4.81	0.298	5.0	0.976	3.4e-28	5.48	0.324	0.954	4.51	0.311	5.0	0.961	1.27e-24
HCC1806	QL-IV-100	2	sigmoid	sigmoid	HCC1806 QL-IV-100 0 2	9	2.714	0.334	-0.269	0.453	0.46	-0.309	1.51	0.992	8.44e-37	0.292	0.065	0.615	0.28	0.0247	1.22	0.99	8.24e-35
HCC1806	QL-IV-100	1	sigmoid	sigmoid	HCC1806 QL-IV-100 0 1	9	2.619	0.303	-0.286	0.47	0.414	-0.317	1.57	0.992	4.02e-36	0.274	0.0675	0.611	0.259	0.0348	1.29	0.99	8.31e-35
HCC70	Torin1	2	sigmoid	sigmoid	HCC70 Torin1 0 2	9	1.573	0.0399	-0.322	0.653	0.107	-0.343	0.53	0.962	7.04e-25	0.123	0.183	0.557	0.0522	0.201	0.6	0.964	3.46e-25
HCC1806	QL-IV-100	3	sigmoid	sigmoid	HCC1806 QL-IV-100 0 3	9	2.697	0.287	-0.301	0.472	0.412	-0.344	1.45	0.995	2.12e-39	0.252	0.0588	0.608	0.24	0.0305	1.31	0.992	2.13e-36
HCC1806	QL-XII-61	2	sigmoid	sigmoid	HCC1806 QL-XII-61 0 2	9	2.714	5.89	0.373	0.0452	4.56	0.36	5.0	0.979	1.48e-27	5.48	0.361	0.953	4.3	0.352	5.0	0.971	2.71e-25
HCC1806	QL-VI-86	1	sigmoid	sigmoid	HCC1806 QL-VI-86 0 1	9	2.619	1.41	-0.214	0.244	2.16	-0.376	1.31	0.997	1.33e-44	1.28	0.0866	0.776	1.21	0.0401	1.42	0.995	1.89e-39
HCC1806	AZD8055	3	sigmoid	sigmoid	HCC1806 AZD8055 0 3	9	2.697	0.249	0.382	0.325	0.0778	0.383	1.25	0.992	1.75e-36	0.177	0.369	0.652	0.061	0.37	1.26	0.992	2.49e-36
HCC1806	QL-XII-61	1	sigmoid	sigmoid	HCC1806 QL-XII-61 0 1	9	2.619	6.9	0.407	0.0291	5.14	0.386	5.0	0.962	5.78e-25	6.52	0.4	0.974	4.87	0.384	5.0	0.956	8.68e-24
HCC1806	Torin2	1	sigmoid	sigmoid	HCC1806 Torin2 0 1	9	2.619	0.0655	-0.43	0.683	0.107	-0.389	1.17	0.994	7.49e-39	0.0584	0.0375	0.456	0.0546	0.0391	1.2	0.997	3.89e-44
HCC1806	Torin2	2	sigmoid	sigmoid	HCC1806 Torin2 0 2	9	2.714	0.0767	-0.467	0.658	0.13	-0.401	1.12	0.99	2.21e-34	0.0654	0.0278	0.465	0.062	0.0296	1.13	0.994	4.16e-38

<
<<
Previous
Page 1 of 3
Next
>>
>
1 to 25 of 71 records
per page:

HMS LINCS Project

Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 2 of 2: GR metrics. - Dataset (ID:20367)