LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trametinib | 180614_BG_04 | 15430 | 0.0190 | 88 | 207 | 12 | 19 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_9 | 295 | 0.0188 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00124 | 0.9536 |
| Taxol | 180622_BG_7 | 20507 | 0.0237 | 71 | 417 | 8 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_5 | 488 | 0.0232 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00288 | 1.0106 |
| Trametinib | 180614_BG_04 | 15907 | 0.0293 | 202 | 270 | 7 | 11 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_8 | 472 | 0.0288 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00882 | 0.9676 |
| Trametinib | 180614_BG_03 | 16284 | 0.0153 | 39 | 210 | 3 | 19 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_4 | 249 | 0.0151 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00493 | 0.9784 |
| Taxol | 180622_BG_6 | 19186 | 0.0223 | 78 | 352 | 12 | 5 | Paclitaxel | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_2 | 430 | 0.0219 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00420 | 0.9816 |
| Taxol | 180622_BG_7 | 19820 | 0.0240 | 62 | 416 | 6 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_4 | 478 | 0.0235 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00258 | 0.9957 |
| Trametinib | 180614_BG_03 | 15977 | 0.0189 | 86 | 217 | 4 | 17 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_5 | 303 | 0.0186 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00138 | 0.9696 |
| Trametinib | 180614_BG_04 | 15582 | 0.0234 | 133 | 234 | 5 | 16 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_7 | 367 | 0.0230 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00302 | 0.9581 |
| Trametinib | 180614_BG_02 | 16460 | 0.0169 | 28 | 250 | 11 | 11 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_3 | 278 | 0.0166 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00339 | 0.9834 |
| Taxol | 180614_BG_03 | 17286 | 0.0205 | 72 | 284 | 6 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_4 | 356 | 0.0202 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00018 | 1.0063 |
| Taxol | 180622_BG_6 | 19176 | 0.0246 | 139 | 336 | 7 | 15 | Paclitaxel | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_1 | 475 | 0.0242 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00195 | 0.9814 |
| Taxol | 180614_BG_04 | 17284 | 0.0174 | 61 | 241 | 13 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_9 | 302 | 0.0172 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00282 | 1.0063 |
| Taxol | 180614_BG_04 | 17665 | 0.0223 | 93 | 303 | 10 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_8 | 396 | 0.0219 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00193 | 1.0166 |
| Taxol | 180622_BG_6 | 20268 | 0.0327 | 150 | 518 | 13 | 7 | Paclitaxel | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_3 | 668 | 0.0319 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.00578 | 1.0055 |
| Taxol | 180614_BG_03 | 17225 | 0.0205 | 97 | 258 | 13 | 17 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_6 | 355 | 0.0202 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00020 | 1.0047 |
| Trametinib | 180614_BG_02 | 16908 | 0.0187 | 50 | 267 | 10 | 4 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_2 | 317 | 0.0184 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00159 | 0.9960 |
| Trametinib | 180614_BG_02 | 16814 | 0.0194 | 28 | 298 | 9 | 20 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_1 | 326 | 0.0190 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00098 | 0.9934 |
| Trametinib | 180614_BG_03 | 15593 | 0.0198 | 86 | 225 | 14 | 19 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_6 | 311 | 0.0196 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00044 | 0.9584 |
| Taxol | 180614_BG_02 | 17244 | 0.0174 | 26 | 274 | 7 | 15 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_1 | 300 | 0.0171 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00290 | 1.0052 |
| Taxol | 180614_BG_03 | 17719 | 0.0215 | 70 | 312 | 8 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_5 | 382 | 0.0211 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00111 | 1.0180 |
| Taxol | 180614_BG_02 | 17049 | 0.0180 | 35 | 273 | 12 | 5 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_2 | 308 | 0.0177 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00225 | 0.9999 |
| Taxol | 180614_BG_02 | 16768 | 0.0226 | 39 | 340 | 13 | 7 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_3 | 379 | 0.0221 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00211 | 0.9921 |
| Taxol | 180614_BG_04 | 18063 | 0.0199 | 70 | 290 | 9 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_7 | 360 | 0.0195 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00045 | 1.0272 |
| Taxol | 180622_BG_8 | 20588 | 0.0248 | 57 | 455 | 9 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_7 | 512 | 0.0243 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00186 | 1.0123 |
| Taxol | 180622_BG_7 | 19664 | 0.0204 | 31 | 370 | 13 | 17 | Paclitaxel | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_6 | 401 | 0.0200 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00614 | 0.9923 |