LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180614_BG_02 | 12302 | 0.0143 | 23 | 153 | 5 | 3 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_1 | 176 | 0.0141 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00589 | 0.8524 |
| Alpelisib | 180614_BG_02 | 5565 | 0.0221 | 45 | 79 | 9 | 4 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 124 | 0.0218 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00180 | 0.5378 |
| Alpelisib | 180614_BG_02 | 13929 | 0.0157 | 24 | 195 | 5 | 20 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_1 | 219 | 0.0155 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00452 | 0.9072 |
| Alpelisib | 180614_BG_02 | 15179 | 0.0167 | 42 | 212 | 12 | 6 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_3 | 254 | 0.0165 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00354 | 0.9461 |
| Alpelisib | 180614_BG_02 | 9366 | 0.0236 | 56 | 166 | 6 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_1 | 222 | 0.0232 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00316 | 0.7376 |
| Alpelisib | 180614_BG_02 | 5374 | 0.0236 | 46 | 82 | 8 | 17 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 128 | 0.0233 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00327 | 0.5253 |
| Alpelisib | 180614_BG_02 | 16888 | 0.0194 | 31 | 298 | 9 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_2 | 329 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00089 | 0.9954 |
| Alpelisib | 180614_BG_02 | 16850 | 0.0166 | 37 | 243 | 12 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 280 | 0.0163 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00365 | 0.9944 |
| Alpelisib | 180614_BG_02 | 16563 | 0.0198 | 43 | 285 | 3 | 12 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 328 | 0.0194 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00058 | 0.9863 |
| Alpelisib | 180614_BG_02 | 14209 | 0.0190 | 32 | 239 | 11 | 22 | Alpelisib | 0.316033316 | treatment | 72 | 1 | MCF10A-GM_2 | 271 | 0.0187 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00128 | 0.9162 |
| Alpelisib | 180614_BG_02 | 12914 | 0.0165 | 44 | 170 | 12 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_3 | 214 | 0.0163 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00369 | 0.8737 |
| Alpelisib | 180614_BG_02 | 12312 | 0.0199 | 56 | 190 | 6 | 5 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_2 | 246 | 0.0196 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00041 | 0.8528 |
| Alpelisib | 180614_BG_02 | 9989 | 0.0227 | 56 | 172 | 8 | 7 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_2 | 228 | 0.0223 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00232 | 0.7641 |
| Alpelisib | 180614_BG_02 | 9583 | 0.0225 | 50 | 167 | 10 | 5 | Alpelisib | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_3 | 217 | 0.0221 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00215 | 0.7470 |
| Alpelisib | 180614_BG_02 | 17762 | 0.0225 | 55 | 346 | 8 | 11 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 401 | 0.0221 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00208 | 1.0192 |
| Alpelisib | 180614_BG_02 | 15804 | 0.0194 | 71 | 237 | 3 | 7 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_1 | 308 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00088 | 0.9646 |
| Alpelisib | 180614_BG_02 | 15928 | 0.0147 | 16 | 219 | 10 | 18 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_3 | 235 | 0.0145 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00546 | 0.9682 |
| Alpelisib | 180614_BG_02 | 16925 | 0.0228 | 77 | 311 | 13 | 4 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_1 | 388 | 0.0224 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00242 | 0.9964 |
| Alpelisib | 180614_BG_02 | 17099 | 0.0205 | 34 | 317 | 13 | 13 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_2 | 351 | 0.0201 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00012 | 1.0012 |
| Alpelisib | 180614_BG_02 | 16699 | 0.0169 | 46 | 237 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_3 | 283 | 0.0167 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00333 | 0.9901 |
| Alpelisib | 180614_BG_02 | 16954 | 0.0137 | 33 | 199 | 13 | 15 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 232 | 0.0135 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00650 | 0.9972 |
| Alpelisib | 180614_BG_02 | 17542 | 0.0211 | 36 | 335 | 7 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 371 | 0.0207 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00072 | 1.0133 |
| Alpelisib | 180614_BG_02 | 16621 | 0.0177 | 25 | 270 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 295 | 0.0174 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00256 | 0.9880 |
| Dasatinib | 180614_BG_02 | 17360 | 0.0204 | 53 | 303 | 3 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 356 | 0.0201 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00010 | 1.0084 |
| Alpelisib | 180614_BG_02 | 5488 | 0.0212 | 27 | 90 | 12 | 19 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 117 | 0.0209 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00088 | 0.5328 |