LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180703_BG_11 | 21433 | 0.0293 | 76 | 555 | 12 | 5 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 631 | 0.0286 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00320 | 0.9969 |
| Alpelisib | 180703_BG_11 | 20509 | 0.0293 | 99 | 504 | 6 | 7 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_5 | 603 | 0.0286 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00324 | 0.9748 |
| Alpelisib | 180703_BG_12 | 21504 | 0.0307 | 79 | 583 | 9 | 21 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 662 | 0.0299 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00193 | 0.9986 |
| Alpelisib | 180703_BG_11 | 21322 | 0.0301 | 117 | 529 | 10 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 646 | 0.0294 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00239 | 0.9943 |
| Alpelisib | 180703_BG_10 | 20891 | 0.0207 | 65 | 368 | 13 | 4 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_1 | 433 | 0.0203 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01149 | 0.9840 |
| Alpelisib | 180703_BG_11 | 21264 | 0.0273 | 195 | 390 | 3 | 18 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_4 | 585 | 0.0268 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00502 | 0.9929 |
| Alpelisib | 180703_BG_10 | 21342 | 0.0259 | 35 | 518 | 12 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 553 | 0.0253 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00654 | 0.9948 |
| Alpelisib | 180703_BG_11 | 21161 | 0.0363 | 120 | 652 | 13 | 15 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_6 | 772 | 0.0352 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00340 | 0.9905 |
| Alpelisib | 180703_BG_10 | 21952 | 0.0290 | 45 | 594 | 3 | 12 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 639 | 0.0283 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00351 | 1.0090 |
| Alpelisib | 180703_BG_11 | 21168 | 0.0360 | 131 | 636 | 5 | 4 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 767 | 0.0350 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00317 | 0.9906 |
| Alpelisib | 180703_BG_12 | 21518 | 0.0366 | 44 | 745 | 14 | 4 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 789 | 0.0354 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00357 | 0.9989 |
| Alpelisib | 180703_BG_12 | 22004 | 0.0359 | 56 | 737 | 14 | 10 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 793 | 0.0348 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00299 | 1.0102 |
| Alpelisib | 180703_BG_10 | 21247 | 0.0295 | 54 | 575 | 13 | 13 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_2 | 629 | 0.0288 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00305 | 0.9925 |
| Alpelisib | 180703_BG_10 | 20811 | 0.0261 | 54 | 490 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_3 | 544 | 0.0255 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00632 | 0.9821 |
| Alpelisib | 180703_BG_10 | 21555 | 0.0242 | 61 | 463 | 7 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 524 | 0.0237 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00807 | 0.9998 |
| Alpelisib | 180703_BG_10 | 21511 | 0.0279 | 49 | 552 | 8 | 11 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 601 | 0.0272 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00462 | 0.9987 |
| Alpelisib | 180703_BG_11 | 21795 | 0.0345 | 187 | 572 | 3 | 13 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_4 | 759 | 0.0337 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00185 | 1.0054 |
| Alpelisib | 180703_BG_11 | 21507 | 0.0339 | 123 | 611 | 8 | 17 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_5 | 734 | 0.0330 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00120 | 0.9986 |
| Alpelisib | 180703_BG_12 | 21706 | 0.0371 | 74 | 734 | 11 | 6 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 808 | 0.0359 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00409 | 1.0033 |
| Alpelisib | 180703_BG_12 | 21437 | 0.0315 | 58 | 619 | 13 | 22 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 677 | 0.0306 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00119 | 0.9970 |
| Alpelisib | 180703_BG_10 | 21207 | 0.0284 | 46 | 557 | 13 | 15 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 603 | 0.0276 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00415 | 0.9916 |
| Alpelisib | 180703_BG_10 | 21490 | 0.0237 | 36 | 474 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 510 | 0.0232 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00862 | 0.9982 |
| Alpelisib | 180703_BG_12 | 21460 | 0.0306 | 67 | 591 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 658 | 0.0297 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00205 | 0.9975 |
| Alpelisib | 180703_BG_12 | 21491 | 0.0353 | 72 | 690 | 5 | 18 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_7 | 762 | 0.0342 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00244 | 0.9983 |
| Alpelisib | 180703_BG_11 | 21021 | 0.0297 | 117 | 511 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_6 | 628 | 0.0290 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00279 | 0.9871 |