LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Palbociclib | 180703_BG_10 | 7774 | 0.0109 | 39 | 46 | 12 | 13 | Palbociclib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_3 | 85 | 0.0108 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.02098 | 0.5455 |
| Palbociclib | 180703_BG_10 | 7560 | 0.0111 | 37 | 47 | 4 | 21 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_2 | 84 | 0.0110 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.02081 | 0.5347 |
| Trametinib | 180614_BG_02 | 12915 | 0.0120 | 18 | 137 | 10 | 19 | Trametinib | 0.000998 | treatment | 72 | 1 | MCF10A-GM_2 | 155 | 0.0119 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00814 | 0.8737 |
| Trametinib | 180703_BG_10 | 14550 | 0.0125 | 57 | 125 | 10 | 19 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_2 | 182 | 0.0124 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01945 | 0.8107 |
| Palbociclib | 180614_BG_02 | 17421 | 0.0127 | 25 | 196 | 10 | 12 | Palbociclib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_1 | 221 | 0.0125 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00747 | 1.0100 |
| Neratinib | 180703_BG_10 | 14443 | 0.0129 | 30 | 157 | 11 | 14 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_1 | 187 | 0.0128 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01902 | 0.8074 |
| Neratinib | 180703_BG_10 | 14578 | 0.0129 | 38 | 151 | 14 | 18 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_3 | 189 | 0.0128 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01900 | 0.8116 |
| Trametinib | 180614_BG_03 | 12337 | 0.0130 | 46 | 115 | 7 | 15 | Trametinib | 0.000998 | treatment | 72 | 1 | MCF10A-GM_5 | 161 | 0.0129 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00711 | 0.8537 |
| Trametinib | 180703_BG_12 | 11390 | 0.0132 | 48 | 103 | 14 | 12 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 151 | 0.0131 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01872 | 0.7021 |
| Trametinib | 180703_BG_10 | 14205 | 0.0133 | 46 | 144 | 6 | 8 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_1 | 190 | 0.0132 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01860 | 0.7998 |
| Neratinib | 180614_BG_02 | 16720 | 0.0134 | 11 | 213 | 7 | 21 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 224 | 0.0132 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00678 | 0.9907 |
| Dasatinib | 180614_BG_03 | 16537 | 0.0134 | 64 | 159 | 9 | 15 | Dasatinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 223 | 0.0133 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00669 | 0.9856 |
| Etoposide | 180614_BG_02 | 14897 | 0.0135 | 20 | 181 | 11 | 21 | Etoposide | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_2 | 201 | 0.0133 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00668 | 0.9375 |
| Alpelisib | 180703_BG_10 | 10077 | 0.0135 | 44 | 93 | 8 | 7 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_2 | 137 | 0.0134 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01839 | 0.6502 |
| Alpelisib | 180614_BG_03 | 5617 | 0.0136 | 26 | 51 | 5 | 22 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 77 | 0.0135 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00647 | 0.5412 |
| Alpelisib | 180703_BG_10 | 7647 | 0.0137 | 32 | 73 | 12 | 19 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_3 | 105 | 0.0135 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01825 | 0.5391 |
| Alpelisib | 180614_BG_02 | 16954 | 0.0137 | 33 | 199 | 13 | 15 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 232 | 0.0135 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00650 | 0.9972 |
| Etoposide | 180703_BG_10 | 13559 | 0.0136 | 48 | 137 | 9 | 13 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_2 | 185 | 0.0135 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01834 | 0.7787 |
| Alpelisib | 180703_BG_10 | 14895 | 0.0138 | 47 | 159 | 12 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_3 | 206 | 0.0136 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01816 | 0.8215 |
| Neratinib | 180614_BG_03 | 16626 | 0.0137 | 59 | 170 | 14 | 11 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_6 | 229 | 0.0136 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00641 | 0.9881 |
| Trametinib | 180703_BG_10 | 9284 | 0.0140 | 50 | 81 | 12 | 21 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 131 | 0.0139 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01789 | 0.6164 |
| Palbociclib | 180703_BG_10 | 17887 | 0.0142 | 38 | 216 | 9 | 7 | Palbociclib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_1 | 254 | 0.0140 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01780 | 0.9077 |
| Dasatinib | 180703_BG_10 | 18337 | 0.0142 | 51 | 210 | 12 | 18 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_3 | 261 | 0.0140 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01777 | 0.9197 |
| Alpelisib | 180614_BG_02 | 12302 | 0.0143 | 23 | 153 | 5 | 3 | Alpelisib | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_1 | 176 | 0.0141 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00589 | 0.8524 |
| Alpelisib | 180622_BG_8 | 12474 | 0.0143 | 37 | 142 | 10 | 10 | Alpelisib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_8 | 179 | 0.0141 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.01198 | 0.8041 |