LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpelisib | 180614_BG_02 | 17542 | 0.0211 | 36 | 335 | 7 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 371 | 0.0207 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00072 | 1.0133 |
Alpelisib | 180614_BG_02 | 17762 | 0.0225 | 55 | 346 | 8 | 11 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 401 | 0.0221 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00208 | 1.0192 |
Alpelisib | 180614_BG_02 | 16850 | 0.0166 | 37 | 243 | 12 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 280 | 0.0163 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00365 | 0.9944 |
Alpelisib | 180614_BG_03 | 16253 | 0.0172 | 65 | 216 | 3 | 13 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 281 | 0.0170 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00300 | 0.9775 |
Alpelisib | 180614_BG_03 | 17388 | 0.0184 | 67 | 254 | 8 | 17 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_5 | 321 | 0.0181 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00187 | 1.0091 |
Alpelisib | 180614_BG_03 | 17461 | 0.0174 | 55 | 249 | 13 | 15 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_6 | 304 | 0.0171 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00288 | 1.0111 |
Alpelisib | 180614_BG_04 | 17826 | 0.0232 | 118 | 298 | 9 | 21 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_7 | 416 | 0.0228 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00281 | 1.0209 |
Alpelisib | 180614_BG_04 | 17109 | 0.0219 | 125 | 253 | 11 | 6 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_8 | 378 | 0.0216 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00162 | 1.0015 |
Alpelisib | 180614_BG_04 | 16461 | 0.0158 | 45 | 215 | 13 | 22 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_9 | 260 | 0.0155 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00445 | 0.9835 |
Alpelisib | 180614_BG_02 | 16563 | 0.0198 | 43 | 285 | 3 | 12 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 328 | 0.0194 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00058 | 0.9863 |
Alpelisib | 180614_BG_02 | 16954 | 0.0137 | 33 | 199 | 13 | 15 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 232 | 0.0135 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00650 | 0.9972 |
Alpelisib | 180614_BG_02 | 16621 | 0.0177 | 25 | 270 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 295 | 0.0174 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00256 | 0.9880 |
Alpelisib | 180614_BG_03 | 17024 | 0.0176 | 71 | 230 | 5 | 4 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 301 | 0.0174 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00262 | 0.9992 |
Alpelisib | 180614_BG_03 | 16550 | 0.0151 | 53 | 198 | 10 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 251 | 0.0149 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00506 | 0.9860 |
Alpelisib | 180614_BG_03 | 16896 | 0.0172 | 51 | 241 | 12 | 5 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 292 | 0.0170 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00301 | 0.9956 |
Alpelisib | 180614_BG_04 | 16866 | 0.0150 | 64 | 190 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 254 | 0.0148 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00516 | 0.9948 |
Alpelisib | 180614_BG_04 | 17433 | 0.0197 | 108 | 238 | 14 | 4 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_8 | 346 | 0.0195 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00053 | 1.0103 |
Alpelisib | 180614_BG_04 | 16325 | 0.0255 | 114 | 305 | 14 | 10 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_9 | 419 | 0.0250 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00503 | 0.9796 |
Alpelisib | 180614_BG_02 | 16925 | 0.0228 | 77 | 311 | 13 | 4 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_1 | 388 | 0.0224 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00242 | 0.9964 |
Alpelisib | 180614_BG_02 | 17099 | 0.0205 | 34 | 317 | 13 | 13 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_2 | 351 | 0.0201 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00012 | 1.0012 |
Alpelisib | 180614_BG_02 | 16699 | 0.0169 | 46 | 237 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_3 | 283 | 0.0167 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00333 | 0.9901 |
Alpelisib | 180614_BG_03 | 16778 | 0.0235 | 79 | 317 | 3 | 18 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_4 | 396 | 0.0231 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00306 | 0.9924 |
Alpelisib | 180614_BG_03 | 16397 | 0.0156 | 59 | 198 | 6 | 7 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_5 | 257 | 0.0154 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00456 | 0.9816 |
Alpelisib | 180614_BG_03 | 16992 | 0.0167 | 38 | 247 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_6 | 285 | 0.0165 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00350 | 0.9983 |
Alpelisib | 180614_BG_04 | 16235 | 0.0264 | 125 | 307 | 5 | 18 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_7 | 432 | 0.0259 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00592 | 0.9770 |