LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180703_BG_12 | 11804 | 0.0241 | 86 | 201 | 5 | 19 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_7 | 287 | 0.0237 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00806 | 0.7175 |
| Alpelisib | 180703_BG_12 | 8484 | 0.0196 | 52 | 115 | 10 | 14 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_7 | 167 | 0.0193 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01249 | 0.5800 |
| Alpelisib | 180703_BG_12 | 18572 | 0.0194 | 66 | 296 | 12 | 22 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_9 | 362 | 0.0191 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01268 | 0.9259 |
| Alpelisib | 180703_BG_12 | 14515 | 0.0206 | 90 | 211 | 7 | 18 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_9 | 301 | 0.0203 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01148 | 0.8096 |
| Alpelisib | 180703_BG_12 | 11660 | 0.0184 | 68 | 148 | 14 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_9 | 216 | 0.0182 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01361 | 0.7122 |
| Alpelisib | 180703_BG_12 | 8407 | 0.0239 | 70 | 133 | 9 | 22 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 203 | 0.0236 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00822 | 0.5764 |
| Alpelisib | 180703_BG_12 | 19908 | 0.0208 | 43 | 372 | 6 | 5 | Alpelisib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_9 | 415 | 0.0204 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01138 | 0.9600 |
| Alpelisib | 180703_BG_12 | 17630 | 0.0163 | 44 | 244 | 6 | 12 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_8 | 288 | 0.0161 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01573 | 0.9007 |
| Alpelisib | 180703_BG_12 | 13199 | 0.0158 | 49 | 160 | 4 | 12 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_7 | 209 | 0.0156 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01621 | 0.7667 |
| Alpelisib | 180703_BG_12 | 15689 | 0.0186 | 94 | 199 | 5 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_8 | 293 | 0.0183 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01347 | 0.8455 |
| Alpelisib | 180703_BG_12 | 12063 | 0.0162 | 30 | 166 | 10 | 10 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_8 | 196 | 0.0160 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01581 | 0.7270 |
| Alpelisib | 180703_BG_12 | 22004 | 0.0359 | 56 | 737 | 14 | 10 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 793 | 0.0348 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00299 | 1.0102 |
| Alpelisib | 180703_BG_12 | 21518 | 0.0366 | 44 | 745 | 14 | 4 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 789 | 0.0354 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00357 | 0.9989 |
| Alpelisib | 180703_BG_12 | 21398 | 0.0358 | 83 | 686 | 3 | 15 | Alpelisib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_7 | 769 | 0.0347 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00289 | 0.9961 |
| Alpelisib | 180703_BG_12 | 21504 | 0.0307 | 79 | 583 | 9 | 21 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 662 | 0.0299 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00193 | 0.9986 |
| Alpelisib | 180703_BG_12 | 21491 | 0.0353 | 72 | 690 | 5 | 18 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_7 | 762 | 0.0342 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00244 | 0.9983 |
| Alpelisib | 180703_BG_12 | 20218 | 0.0288 | 86 | 499 | 5 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_8 | 585 | 0.0281 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00368 | 0.9677 |
| Alpelisib | 180703_BG_12 | 19196 | 0.0208 | 53 | 348 | 4 | 14 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_7 | 401 | 0.0205 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01134 | 0.9421 |
| Alpelisib | 180703_BG_12 | 21706 | 0.0371 | 74 | 734 | 11 | 6 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 808 | 0.0359 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00409 | 1.0033 |
| Alpelisib | 180703_BG_12 | 21437 | 0.0315 | 58 | 619 | 13 | 22 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 677 | 0.0306 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00119 | 0.9970 |
| Alpelisib | 180703_BG_12 | 22357 | 0.0406 | 76 | 834 | 9 | 15 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_9 | 910 | 0.0391 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00731 | 1.0183 |
| Alpelisib | 180703_BG_12 | 21075 | 0.0325 | 78 | 609 | 7 | 14 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_8 | 687 | 0.0316 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00023 | 0.9884 |
| Alpelisib | 180703_BG_12 | 21460 | 0.0306 | 67 | 591 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 658 | 0.0297 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00205 | 0.9975 |
| Dasatinib | 180703_BG_12 | 20044 | 0.0203 | 54 | 354 | 6 | 19 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 408 | 0.0199 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01185 | 0.9634 |
| Alpelisib | 180703_BG_12 | 7421 | 0.0235 | 57 | 119 | 14 | 14 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_8 | 176 | 0.0232 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00863 | 0.5275 |