LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Dasatinib | 180614_BG_04 | 811 | 0.5853 | 127 | 422 | 11 | 16 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_9 | 549 | 0.4037 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.38368 | -0.0213 |
| Etoposide | 180614_BG_03 | 933 | 0.1292 | 81 | 50 | 7 | 17 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 131 | 0.1231 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.10312 | 0.0114 |
| Dasatinib | 180614_BG_03 | 768 | 0.5763 | 77 | 410 | 6 | 4 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 487 | 0.3880 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.36805 | -0.0337 |
| Dasatinib | 180614_BG_04 | 691 | 0.6431 | 172 | 383 | 7 | 16 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_8 | 555 | 0.4454 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.42543 | -0.0574 |
| Etoposide | 180614_BG_02 | 1004 | 0.0740 | 37 | 40 | 10 | 7 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 77 | 0.0712 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.05123 | 0.0290 |
| Etoposide | 180614_BG_03 | 955 | 0.1212 | 85 | 41 | 4 | 13 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 126 | 0.1166 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.09656 | 0.0170 |
| Dasatinib | 180614_BG_02 | 684 | 0.6242 | 77 | 398 | 4 | 13 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 475 | 0.4098 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.38984 | -0.0596 |
| Dasatinib | 180614_BG_02 | 735 | 0.5538 | 65 | 378 | 8 | 19 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 443 | 0.3761 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.35607 | -0.0436 |
| Dasatinib | 180614_BG_03 | 696 | 0.5938 | 77 | 382 | 12 | 19 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 459 | 0.3974 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.37741 | -0.0558 |
| Dasatinib | 180614_BG_04 | 750 | 0.5615 | 144 | 358 | 5 | 8 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 502 | 0.4010 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.38096 | -0.0391 |
| Etoposide | 180614_BG_02 | 888 | 0.0722 | 26 | 40 | 6 | 22 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 66 | 0.0692 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04919 | -0.0003 |
| Alpelisib | 180614_BG_03 | 5617 | 0.0136 | 26 | 51 | 5 | 22 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 77 | 0.0135 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00647 | 0.5412 |
| Alpelisib | 180614_BG_03 | 5521 | 0.0329 | 104 | 81 | 3 | 11 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 185 | 0.0324 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01243 | 0.5350 |
| Alpelisib | 180614_BG_02 | 5488 | 0.0212 | 27 | 90 | 12 | 19 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 117 | 0.0209 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00088 | 0.5328 |
| Alpelisib | 180614_BG_02 | 5565 | 0.0221 | 45 | 79 | 9 | 4 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 124 | 0.0218 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00180 | 0.5378 |
| Alpelisib | 180614_BG_04 | 7371 | 0.0251 | 90 | 97 | 9 | 22 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 187 | 0.0247 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00475 | 0.6427 |
| Alpelisib | 180614_BG_03 | 5511 | 0.0245 | 70 | 67 | 6 | 16 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 137 | 0.0243 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00426 | 0.5343 |
| Dasatinib | 180614_BG_02 | 685 | 0.6173 | 65 | 398 | 7 | 11 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 463 | 0.4033 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.38331 | -0.0593 |
| Alpelisib | 180614_BG_02 | 5374 | 0.0236 | 46 | 82 | 8 | 17 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 128 | 0.0233 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00327 | 0.5253 |
| Dasatinib | 180614_BG_03 | 769 | 0.5421 | 98 | 372 | 7 | 19 | Dasatinib | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 470 | 0.3793 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.35934 | -0.0334 |
| Alpelisib | 180614_BG_04 | 6752 | 0.0288 | 113 | 85 | 10 | 14 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_8 | 198 | 0.0285 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00849 | 0.6092 |
| Alpelisib | 180614_BG_04 | 6841 | 0.0354 | 169 | 79 | 14 | 14 | Alpelisib | 9.98 | treatment | 72 | 1 | MCF10A-GM_9 | 248 | 0.0350 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01499 | 0.6142 |
| Etoposide | 180614_BG_02 | 1013 | 0.0862 | 54 | 38 | 4 | 15 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 92 | 0.0833 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.06326 | 0.0311 |
| Etoposide | 180614_BG_04 | 1173 | 0.1443 | 95 | 88 | 9 | 8 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 183 | 0.1350 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.11496 | 0.0672 |
| Etoposide | 180614_BG_03 | 1029 | 0.0982 | 61 | 46 | 14 | 16 | Etoposide | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 107 | 0.0942 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07419 | 0.0349 |