LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | 180703_BG_11 | 2317 | 0.6493 | 728 | 1249 | 13 | 5 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 1977 | 0.4604 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.42861 | 0.1383 |
| Taxol | 180703_BG_11 | 1739 | 0.7248 | 677 | 1074 | 5 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 1751 | 0.5017 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.46992 | 0.0587 |
| Taxol | 180703_BG_10 | 2069 | 0.6300 | 493 | 1121 | 3 | 9 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 1614 | 0.4382 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.40643 | 0.1062 |
| Taxol | 180703_BG_12 | 2901 | 0.4723 | 457 | 1129 | 14 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 1586 | 0.3535 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.32167 | 0.2048 |
| Taxol | 180703_BG_12 | 2585 | 0.5196 | 421 | 1141 | 3 | 14 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 1562 | 0.3767 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.34486 | 0.1702 |
| Taxol | 180703_BG_12 | 3131 | 0.4436 | 381 | 1177 | 12 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 1558 | 0.3323 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.30047 | 0.2282 |
| Taxol | 180703_BG_11 | 2233 | 0.5700 | 467 | 1072 | 11 | 11 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 1539 | 0.4080 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.37621 | 0.1277 |
| Taxol | 180703_BG_11 | 10048 | 0.1286 | 377 | 964 | 9 | 9 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_4 | 1341 | 0.1177 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.08595 | 0.6490 |
| Taxol | 180703_BG_11 | 649 | 1.0786 | 522 | 741 | 11 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_5 | 1263 | 0.6606 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.62877 | -0.1747 |
| Taxol | 180703_BG_10 | 1898 | 0.5739 | 287 | 967 | 4 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 1254 | 0.3978 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.36604 | 0.0823 |
| Taxol | 180703_BG_10 | 7939 | 0.1506 | 373 | 879 | 5 | 21 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_1 | 1252 | 0.1362 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.10442 | 0.5537 |
| Taxol | 180703_BG_10 | 1845 | 0.5696 | 290 | 926 | 4 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 1216 | 0.3973 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.36546 | 0.0746 |
| Taxol | 180703_BG_12 | 894 | 0.8965 | 372 | 763 | 11 | 18 | Paclitaxel | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_9 | 1135 | 0.5594 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.52759 | -0.1052 |
| Taxol | 180703_BG_10 | 7458 | 0.1455 | 296 | 832 | 7 | 16 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_2 | 1128 | 0.1314 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.09958 | 0.5294 |
| Taxol | 180703_BG_11 | 701 | 0.9199 | 523 | 603 | 13 | 9 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_6 | 1126 | 0.6163 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.58451 | -0.1585 |
| Taxol | 180622_BG_6 | 4185 | 0.2463 | 382 | 743 | 7 | 22 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_3 | 1125 | 0.2119 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.18574 | 0.4220 |
| Taxol | 180703_BG_12 | 972 | 0.8560 | 306 | 788 | 4 | 20 | Paclitaxel | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_7 | 1094 | 0.5295 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.49773 | -0.0861 |
| Taxol | 180703_BG_10 | 1140 | 0.7336 | 343 | 745 | 11 | 7 | Paclitaxel | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_2 | 1088 | 0.4883 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.45653 | -0.0485 |
| Taxol | 180614_BG_04 | 5486 | 0.1841 | 417 | 670 | 13 | 11 | Paclitaxel | 0.002994 | treatment | 72 | 1 | MCF10A-GM_9 | 1087 | 0.1654 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.14538 | 0.5327 |
| Taxol | 180703_BG_11 | 10196 | 0.1030 | 310 | 772 | 14 | 6 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_6 | 1082 | 0.0959 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.06414 | 0.6551 |
| Taxol | 180703_BG_10 | 8562 | 0.1216 | 259 | 814 | 7 | 22 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_3 | 1073 | 0.1114 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.07957 | 0.5837 |
| Taxol | 180622_BG_8 | 6214 | 0.1624 | 351 | 715 | 13 | 11 | Paclitaxel | 0.002994 | treatment | 72 | 2 | MCF10A-GM_9 | 1066 | 0.1464 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.12030 | 0.5499 |
| Taxol | 180703_BG_12 | 684 | 0.9991 | 374 | 683 | 3 | 20 | Paclitaxel | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_7 | 1057 | 0.6071 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.57532 | -0.1637 |
| Taxol | 180703_BG_12 | 689 | 0.9814 | 385 | 669 | 9 | 13 | Paclitaxel | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_8 | 1054 | 0.6047 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.57291 | -0.1622 |
| Taxol | 180703_BG_11 | 920 | 0.8201 | 364 | 689 | 9 | 10 | Paclitaxel | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_5 | 1053 | 0.5337 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.50191 | -0.0987 |