Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
MCF7 RO-3306
6.254157687
 0.0869 0.0697 10.7929 -1.0000 2.0134 0.8978
4.13e-13
MCF7 Rucaparib
20.52571528
 0.5466 0.0691 95.2231 -1.0000 0.7159 0.5083
0.000140012
MCF7 Senexin B
13.10460323
 0.4652 0.2569 1000.0000 -0.6830 0.1987 0.6278
4.31e-06
MCF7 SHP099
inf
 0.8331 0.0289 0.0000 0.9643 0.0100 0.0000
0.073472433
MCF7 THZ1
0.022830734
 -0.4455 0.4917 0.0384 -0.4128 1.1568 0.9820
1.11e-16
MCF7 THZ531
0.061536132
 -0.3360 0.3371 0.0797 -0.2528 1.5809 0.9654
1.11e-16
MDA-MB-134-VI MK 1775
0.087205685
 -0.3434 0.5624 3.0209 -1.0000 0.3099 0.7289
8.21e-08
MDA-MB-134-VI AZD2014
-inf
 -0.7122
MDA-MB-134-VI AZD5363
-inf
 0.3909
MDA-MB-134-VI AZD6738
-inf
 0.1117
MDA-MB-134-VI BMS-265246
-inf
 0.0268
MDA-MB-134-VI Ulixertinib
-inf
 -0.2948
MDA-MB-134-VI Alvocidib
-inf
 -0.4621
MDA-MB-134-VI GSK2334470
-inf
 0.1440
MDA-MB-134-VI Ribociclib
-inf
 0.2592 0.7185 0.0000 0.3047 0.0100 0.0000
0.311703691
MDA-MB-134-VI LY3023414
2.28e-05
 -0.9131 1.4118 0.0019 -1.0000 0.2471 0.8907
9.62e-13
MDA-MB-134-VI RO-3306
-inf
 0.0360
MDA-MB-134-VI Rucaparib
#NAME?
 0.6274
MDA-MB-134-VI Senexin B
-inf
 0.2609
MDA-MB-134-VI SHP099
-inf
 0.8081
MDA-MB-134-VI THZ1
0.006632255
 -0.4554 0.6285 0.0190 -0.5267 0.6824 0.8938
6.71e-13
MDA-MB-134-VI THZ531
0.02115469
 -0.6052 0.6989 0.0314 -0.7400 2.3004 0.9310
3e-15
MDA-MB-157 MK 1775
-inf
 -0.8758
MDA-MB-157 AZD2014
0.179038009
 0.0326 0.4811 86.6841 -1.0000 0.1777 0.5582
3.68e-05
MDA-MB-157 AZD5363
inf
 0.6671 0.0508 0.0000 0.9480 0.0100 0.0000
0.135243927