LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 CHIR-99021
0.37
uM
LJP6
 72
hr
 868 2913 3556 0.8189 0.8123
MDA-MB-231 CHIR-99021
1.11
uM
LJP6
 72
hr
 868 2901 3556 0.8154 0.8086
MDA-MB-231 CHIR-99021
3.33
uM
LJP6
 72
hr
 868 2911 3556 0.8184 0.8119
MDA-MB-231 CHIR-99021
10
uM
LJP6
 72
hr
 868 2866 3556 0.8052 0.7967
MDA-MB-231 Linifanib
0.04
uM
LJP6
 72
hr
 868 3905 3556 1.0987 1.0950
MDA-MB-231 Linifanib
0.12
uM
LJP6
 72
hr
 868 4002 3556 1.1263 1.1205
MDA-MB-231 Linifanib
0.37
uM
LJP6
 72
hr
 868 4037 3556 1.1352 1.1282
MDA-MB-231 Linifanib
1.11
uM
LJP6
 72
hr
 868 3871 3556 1.0879 1.0835
MDA-MB-231 Linifanib
3.33
uM
LJP6
 72
hr
 868 3880 3556 1.0909 1.0872
MDA-MB-231 Linifanib
10
uM
LJP6
 72
hr
 868 1371 3556 0.3851 0.2502
MDA-MB-231 PIK-93
0.04
uM
LJP5
 72
hr
 868 3598 3410 1.0547 1.0539
MDA-MB-231 PIK-93
0.12
uM
LJP5
 72
hr
 868 3631 3410 1.0630 1.0605
MDA-MB-231 PIK-93
0.37
uM
LJP5
 72
hr
 868 3735 3410 1.0944 1.0909
MDA-MB-231 PIK-93
1.11
uM
LJP5
 72
hr
 868 3305 3410 0.9690 0.9682
MDA-MB-231 PIK-93
3.33
uM
LJP5
 72
hr
 868 2602 3410 0.7618 0.7407
MDA-MB-231 PIK-93
10
uM
LJP5
 72
hr
 868 1450 3410 0.4253 0.2963
MDA-MB-231 Dactolisib
0.04
uM
LJP5
 72
hr
 868 2027 3410 0.5943 0.5362
MDA-MB-231 Dactolisib
0.12
uM
LJP5
 72
hr
 868 1811 3410 0.5308 0.4504
MDA-MB-231 Dactolisib
0.37
uM
LJP5
 72
hr
 868 1589 3410 0.4654 0.3565
MDA-MB-231 Dactolisib
1.11
uM
LJP5
 72
hr
 868 1539 3410 0.4512 0.3362
MDA-MB-231 Dactolisib
3.33
uM
LJP5
 72
hr
 868 1479 3410 0.4339 0.3097
MDA-MB-231 Dactolisib
10
uM
LJP5
 72
hr
 868 1555 3410 0.4562 0.3437
MDA-MB-231 Alpelisib
0.04
uM
LJP5
 72
hr
 868 3540 3410 1.0391 1.0395
MDA-MB-231 Alpelisib
0.12
uM
LJP5
 72
hr
 868 3390 3410 0.9929 0.9916
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 72
hr
 868 3413 3410 0.9998 0.9987