LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 TGX221
0.12
uM
LJP5
 72
hr
 868 2538 3410 0.7442 0.7213
MDA-MB-231 TGX221
0.37
uM
LJP5
 72
hr
 868 2555 3410 0.7490 0.7272
MDA-MB-231 TGX221
1.11
uM
LJP5
 72
hr
 868 2919 3410 0.8562 0.8489
MDA-MB-231 TGX221
3.33
uM
LJP5
 72
hr
 868 2001 3410 0.5868 0.5261
MDA-MB-231 TGX221
10
uM
LJP5
 72
hr
 868 2894 3410 0.8488 0.8406
MDA-MB-231 GSK1059615
0.04
uM
LJP5
 72
hr
 868 3825 3410 1.1220 1.1204
MDA-MB-231 GSK1059615
0.04
uM
LJP6
 72
hr
 868 3909 3556 1.1007 1.0969
MDA-MB-231 GSK1059615
0.12
uM
LJP5
 72
hr
 868 3699 3410 1.0848 1.0843
MDA-MB-231 GSK1059615
0.12
uM
LJP6
 72
hr
 868 3571 3556 1.0056 1.0057
MDA-MB-231 GSK1059615
0.37
uM
LJP5
 72
hr
 868 3113 3410 0.9132 0.9103
MDA-MB-231 GSK1059615
0.37
uM
LJP6
 72
hr
 868 3102 3556 0.8743 0.8718
MDA-MB-231 GSK1059615
1.11
uM
LJP5
 72
hr
 868 1671 3410 0.4903 0.3935
MDA-MB-231 GSK1059615
1.11
uM
LJP6
 72
hr
 868 1919 3556 0.5397 0.4766
MDA-MB-231 GSK1059615
3.33
uM
LJP5
 72
hr
 868 781 3410 0.2288 -0.0542
MDA-MB-231 GSK1059615
3.33
uM
LJP6
 72
hr
 868 1178 3556 0.3310 0.1595
MDA-MB-231 GSK1059615
10
uM
LJP5
 72
hr
 868 586 3410 0.1717 -0.1825
MDA-MB-231 GSK1059615
10
uM
LJP6
 72
hr
 868 660 3556 0.1856 -0.1283
MDA-MB-231 Brivanib
0.04
uM
LJP5
 72
hr
 868 2841 3410 0.8315 0.8193
MDA-MB-231 Brivanib
0.12
uM
LJP5
 72
hr
 868 2804 3410 0.8232 0.8118
MDA-MB-231 Brivanib
0.37
uM
LJP5
 72
hr
 868 2967 3410 0.8695 0.8622
MDA-MB-231 Brivanib
1.11
uM
LJP5
 72
hr
 868 2996 3410 0.8785 0.8728
MDA-MB-231 Brivanib
3.33
uM
LJP5
 72
hr
 868 2782 3410 0.8136 0.7970
MDA-MB-231 Brivanib
10
uM
LJP5
 72
hr
 868 2241 3410 0.6564 0.6149
MDA-MB-231 CHIR-99021
0.04
uM
LJP6
 72
hr
 868 3091 3556 0.8691 0.8665
MDA-MB-231 CHIR-99021
0.12
uM
LJP6
 72
hr
 868 2799 3556 0.7880 0.7791