LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF 10A | Radicicol | 3.33 | uM | LJP6 | 72 | hr | 513 | 616 | 10473 | 0.0589 | 0.0419 |
MCF 10A | Radicicol | 10 | uM | LJP5 | 72 | hr | 513 | 347 | 10362 | 0.0336 | -0.0877 |
MCF 10A | Radicicol | 10 | uM | LJP6 | 72 | hr | 513 | 419 | 10473 | 0.0400 | -0.0461 |
MCF 10A | Withaferin A | 0.04 | uM | LJP5 | 72 | hr | 513 | 10161 | 10362 | 0.9806 | 0.9910 |
MCF 10A | Withaferin A | 0.04 | uM | LJP6 | 72 | hr | 513 | 10502 | 10473 | 1.0029 | 1.0010 |
MCF 10A | Withaferin A | 0.12 | uM | LJP5 | 72 | hr | 513 | 9932 | 10362 | 0.9581 | 0.9799 |
MCF 10A | Withaferin A | 0.12 | uM | LJP6 | 72 | hr | 513 | 9535 | 10473 | 0.9104 | 0.9568 |
MCF 10A | Withaferin A | 0.37 | uM | LJP5 | 72 | hr | 513 | 7214 | 10362 | 0.6960 | 0.8395 |
MCF 10A | Withaferin A | 0.37 | uM | LJP6 | 72 | hr | 513 | 6298 | 10473 | 0.6015 | 0.7791 |
MCF 10A | Withaferin A | 1.11 | uM | LJP5 | 72 | hr | 513 | 446 | 10362 | 0.0431 | -0.0317 |
MCF 10A | Withaferin A | 1.11 | uM | LJP6 | 72 | hr | 513 | 502 | 10473 | 0.0480 | -0.0082 |
MCF 10A | Withaferin A | 3.33 | uM | LJP5 | 72 | hr | 513 | 374 | 10362 | 0.0362 | -0.0703 |
MCF 10A | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 513 | 345 | 10473 | 0.0330 | -0.0882 |
MCF 10A | Withaferin A | 10 | uM | LJP5 | 72 | hr | 513 | 321 | 10362 | 0.0310 | -0.1046 |
MCF 10A | Withaferin A | 10 | uM | LJP6 | 72 | hr | 513 | 325 | 10473 | 0.0310 | -0.1050 |