LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | Seliciclib | 0.04 | uM | LJP5 | 72 | hr | 1235 | 4831 | 4267 | 1.1327 | 1.1447 |
MCF7 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1235 | 4452 | 4267 | 1.0429 | 1.0455 |
MCF7 | Seliciclib | 0.37 | uM | LJP5 | 72 | hr | 1235 | 3789 | 4267 | 0.8882 | 0.8715 |
MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1235 | 3527 | 4267 | 0.8263 | 0.7970 |
MCF7 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1235 | 3101 | 4267 | 0.7256 | 0.6698 |
MCF7 | Seliciclib | 10 | uM | LJP5 | 72 | hr | 1235 | 706 | 4267 | 0.1657 | -0.2687 |
MCF7 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3560 | 4056 | 0.8771 | 0.8520 |
MCF7 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1396 | 4056 | 0.3443 | 0.0741 |
MCF7 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 834 | 4056 | 0.2059 | -0.2046 |
MCF7 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 861 | 4056 | 0.2124 | -0.1898 |
MCF7 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 893 | 4056 | 0.2202 | -0.1723 |
MCF7 | AT-7519 | 10 | uM | LJP6 | 72 | hr | 1235 | 735 | 4056 | 0.1810 | -0.2625 |
MCF7 | AZD7762 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1904 | 4056 | 0.4696 | 0.2871 |
MCF7 | AZD7762 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1706 | 4056 | 0.4209 | 0.2074 |
MCF7 | AZD7762 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1544 | 4056 | 0.3810 | 0.1390 |
MCF7 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1310 | 4056 | 0.3230 | 0.0347 |
MCF7 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1057 | 4056 | 0.2607 | -0.0870 |
MCF7 | AZD7762 | 10 | uM | LJP6 | 72 | hr | 1235 | 765 | 4056 | 0.1887 | -0.2437 |
MCF7 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1235 | 1307 | 4056 | 0.3227 | 0.0327 |
MCF7 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1235 | 1319 | 4056 | 0.3253 | 0.0390 |
MCF7 | AZD8055 | 0.37 | uM | LJP6 | 72 | hr | 1235 | 1289 | 4056 | 0.3181 | 0.0251 |
MCF7 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 1291 | 4056 | 0.3187 | 0.0263 |
MCF7 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 1242 | 4056 | 0.3066 | 0.0029 |
MCF7 | AZD8055 | 10 | uM | LJP6 | 72 | hr | 1235 | 1116 | 4056 | 0.2755 | -0.0574 |
MCF7 | Sorafenib | 0.04 | uM | LJP6 | 72 | hr | 1235 | 3940 | 4056 | 0.9719 | 0.9672 |