LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A PF477736
10
uM
LJP5
 72
hr
 513 600 10362 0.0579 0.0360
MCF 10A LDN-193189
0.04
uM
LJP5
 72
hr
 513 10621 10362 1.0251 1.0113
MCF 10A LDN-193189
0.12
uM
LJP5
 72
hr
 513 9904 10362 0.9560 0.9793
MCF 10A LDN-193189
0.37
uM
LJP5
 72
hr
 513 9654 10362 0.9315 0.9675
MCF 10A LDN-193189
1.11
uM
LJP5
 72
hr
 513 8625 10362 0.8322 0.9170
MCF 10A LDN-193189
3.33
uM
LJP5
 72
hr
 513 5692 10362 0.5493 0.7414
MCF 10A LDN-193189
10
uM
LJP5
 72
hr
 513 132 10362 0.0128 -0.2695
MCF 10A PF431396
0.04
uM
LJP5
 72
hr
 513 6160 10362 0.5944 0.7738
MCF 10A PF431396
0.12
uM
LJP5
 72
hr
 513 2639 10362 0.2544 0.4568
MCF 10A PF431396
0.37
uM
LJP5
 72
hr
 513 1183 10362 0.1143 0.2122
MCF 10A PF431396
1.11
uM
LJP5
 72
hr
 513 853 10362 0.0822 0.1229
MCF 10A PF431396
3.33
uM
LJP5
 72
hr
 513 761 10362 0.0734 0.0942
MCF 10A PF431396
10
uM
LJP5
 72
hr
 513 592 10362 0.0572 0.0322
MCF 10A Celastrol
0.04
uM
LJP6
 72
hr
 513 11579 10473 1.1058 1.0464
MCF 10A Celastrol
0.12
uM
LJP6
 72
hr
 513 11759 10473 1.1230 1.0538
MCF 10A Celastrol
0.37
uM
LJP6
 72
hr
 513 6411 10473 0.6124 0.7862
MCF 10A Celastrol
1.11
uM
LJP6
 72
hr
 513 588 10473 0.0562 0.0315
MCF 10A Celastrol
3.33
uM
LJP6
 72
hr
 513 450 10473 0.0430 -0.0312
MCF 10A Celastrol
10
uM
LJP6
 72
hr
 513 525 10473 0.0502 0.0039
MCF 10A SU11274
0.04
uM
LJP5
 72
hr
 513 10462 10362 1.0098 1.0045
MCF 10A SU11274
0.12
uM
LJP5
 72
hr
 513 10030 10362 0.9679 0.9850
MCF 10A SU11274
0.37
uM
LJP5
 72
hr
 513 9431 10362 0.9102 0.9568
MCF 10A SU11274
1.11
uM
LJP5
 72
hr
 513 7883 10362 0.7609 0.8778
MCF 10A SU11274
3.33
uM
LJP5
 72
hr
 513 5510 10362 0.5320 0.7287
MCF 10A SU11274
10
uM
LJP5
 72
hr
 513 2602 10362 0.2512 0.4540