SU11274 - Small Molecule (ID:10119-101)
| HMS LINCS ID: |
10119-101
|
| Name: | SU11274 |
| Alternative Names: | PKI-SU11274 |
| LINCS ID: | LSM-42791 |
| PubChem CID: | 53396327 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 567.17 |
| InChi: | InChI=1S/C28H30ClN5O4S/c1-17-25(30-18(2)26(17)28(36)34-12-10-32(3)11-13-34)16-23-22-15-21(8-9-24(22)31-27(23)35)39(37,38)33(4)20-7-5-6-19(29)14-20/h5-9,14-16,30H,10-13H2,1-4H3,(H,31,35) |
| InChi Key: | FPYJSJDOHRDAMT-UHFFFAOYSA-N |
| SMILES: | CC1=C(NC(=C1C(=O)N2CCN(CC2)C)C)C=C3C4=C(C=CC(=C4)S(=O)(=O)N(C)C5=CC(=CC=C5)Cl)NC3=O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2018-03-30 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
MET, PTK2B | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | CCNE1, CDK2 |
10 (confirmed non-binding) |
Batch Information for HMSL10119-101-1:
| HMS LINCS Batch ID: | 10119-101-1 |
| Provider: | Haoyuan chemexpress |
| Provider Batch ID: | HW-010-20110701 |
| Salt: | 101 |
| Molecular Formula: | C28H30ClN5O4S |
| Molecular Weight: | 568.09 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2011-07-15 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10119-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 04/13/2015 | PASS | HMSL10119-101-1_LCMS.pdf | |
| 11/14/2011 | PASS | None |
(Kd <100 nM)