LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD 5438
0.04
uM
LJP6
 72
hr
 868 3379 3556 0.9500 0.9497
MDA-MB-231 AZD 5438
0.12
uM
LJP6
 72
hr
 868 2534 3556 0.7126 0.6930
MDA-MB-231 AZD 5438
0.37
uM
LJP6
 72
hr
 868 1651 3556 0.4642 0.3710
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 72
hr
 868 886 3556 0.2491 0.0096
MDA-MB-231 AZD 5438
3.33
uM
LJP6
 72
hr
 868 793 3556 0.2234 -0.0435
MDA-MB-231 AZD 5438
10
uM
LJP6
 72
hr
 868 655 3556 0.1843 -0.1293
MDA-MB-231 Pelitinib
0.04
uM
LJP5
 72
hr
 868 3741 3410 1.0982 1.0973
MDA-MB-231 Pelitinib
0.12
uM
LJP5
 72
hr
 868 3662 3410 1.0732 1.0723
MDA-MB-231 Pelitinib
0.37
uM
LJP5
 72
hr
 868 2867 3410 0.8404 0.8309
MDA-MB-231 Pelitinib
1.11
uM
LJP5
 72
hr
 868 2723 3410 0.7981 0.7832
MDA-MB-231 Pelitinib
3.33
uM
LJP5
 72
hr
 868 1535 3410 0.4503 0.3342
MDA-MB-231 Pelitinib
10
uM
LJP5
 72
hr
 868 713 3410 0.2091 -0.0953
MDA-MB-231 Luminespib
0.04
uM
LJP5
 72
hr
 868 1038 3410 0.3049 0.0951
MDA-MB-231 Luminespib
0.12
uM
LJP5
 72
hr
 868 1017 3410 0.2984 0.0834
MDA-MB-231 Luminespib
0.37
uM
LJP5
 72
hr
 868 1067 3410 0.3135 0.1104
MDA-MB-231 Luminespib
1.11
uM
LJP5
 72
hr
 868 1014 3410 0.2974 0.0818
MDA-MB-231 Luminespib
3.33
uM
LJP5
 72
hr
 868 1007 3410 0.2954 0.0780
MDA-MB-231 Luminespib
10
uM
LJP5
 72
hr
 868 951 3410 0.2794 0.0471
MDA-MB-231 AZD8330
0.04
uM
LJP5
 72
hr
 868 939 3410 0.2757 0.0397
MDA-MB-231 AZD8330
0.12
uM
LJP5
 72
hr
 868 981 3410 0.2885 0.0643
MDA-MB-231 AZD8330
0.37
uM
LJP5
 72
hr
 868 919 3410 0.2694 0.0286
MDA-MB-231 AZD8330
1.11
uM
LJP5
 72
hr
 868 1009 3410 0.2962 0.0785
MDA-MB-231 AZD8330
3.33
uM
LJP5
 72
hr
 868 974 3410 0.2855 0.0595
MDA-MB-231 AZD8330
10
uM
LJP5
 72
hr
 868 1031 3410 0.3030 0.0916
MDA-MB-231 TGX221
0.04
uM
LJP5
 72
hr
 868 2426 3410 0.7102 0.6788