LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Buparlisib
10
uM
LJP5
 72
hr
 868 661 3410 0.1935 -0.1307
MDA-MB-231 XL147
0.04
uM
LJP5
 72
hr
 868 3749 3410 1.1007 1.0998
MDA-MB-231 XL147
0.12
uM
LJP5
 72
hr
 868 3671 3410 1.0766 1.0764
MDA-MB-231 XL147
0.37
uM
LJP5
 72
hr
 868 3659 3410 1.0735 1.0735
MDA-MB-231 XL147
1.11
uM
LJP5
 72
hr
 868 3805 3410 1.1168 1.1156
MDA-MB-231 XL147
3.33
uM
LJP5
 72
hr
 868 3611 3410 1.0594 1.0596
MDA-MB-231 XL147
10
uM
LJP5
 72
hr
 868 3316 3410 0.9734 0.9732
MDA-MB-231 Y39983
0.04
uM
LJP6
 72
hr
 868 3238 3556 0.9081 0.9028
MDA-MB-231 Y39983
0.12
uM
LJP6
 72
hr
 868 3097 3556 0.8692 0.8642
MDA-MB-231 Y39983
0.37
uM
LJP6
 72
hr
 868 2848 3556 0.7992 0.7883
MDA-MB-231 Y39983
1.11
uM
LJP6
 72
hr
 868 2552 3556 0.7169 0.6969
MDA-MB-231 Y39983
3.33
uM
LJP6
 72
hr
 868 2074 3556 0.5822 0.5308
MDA-MB-231 Y39983
10
uM
LJP6
 72
hr
 868 573 3556 0.1611 -0.1852
MDA-MB-231 Nintedanib
0.04
uM
LJP6
 72
hr
 868 3852 3556 1.0802 1.0721
MDA-MB-231 Nintedanib
0.12
uM
LJP6
 72
hr
 868 3640 3556 1.0224 1.0203
MDA-MB-231 Nintedanib
0.37
uM
LJP6
 72
hr
 868 3503 3556 0.9838 0.9824
MDA-MB-231 Nintedanib
1.11
uM
LJP6
 72
hr
 868 3044 3556 0.8555 0.8516
MDA-MB-231 Nintedanib
3.33
uM
LJP6
 72
hr
 868 2488 3556 0.6989 0.6757
MDA-MB-231 Nintedanib
10
uM
LJP6
 72
hr
 868 641 3556 0.1802 -0.1394
MDA-MB-231 Foretinib
0.04
uM
LJP5
 72
hr
 868 3236 3410 0.9490 0.9474
MDA-MB-231 Foretinib
0.12
uM
LJP5
 72
hr
 868 2270 3410 0.6661 0.6279
MDA-MB-231 Foretinib
0.37
uM
LJP5
 72
hr
 868 1463 3410 0.4291 0.3026
MDA-MB-231 Foretinib
1.11
uM
LJP5
 72
hr
 868 1337 3410 0.3923 0.2448
MDA-MB-231 Foretinib
3.33
uM
LJP5
 72
hr
 868 1389 3410 0.4072 0.2682
MDA-MB-231 Foretinib
10
uM
LJP5
 72
hr
 868 635 3410 0.1864 -0.1471