LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 PF562271
0.12
uM
LJP6
 72
hr
 868 3076 3556 0.8675 0.8640
MDA-MB-231 PF562271
0.37
uM
LJP6
 72
hr
 868 2810 3556 0.7914 0.7826
MDA-MB-231 PF562271
1.11
uM
LJP6
 72
hr
 868 2382 3556 0.6704 0.6432
MDA-MB-231 PF562271
3.33
uM
LJP6
 72
hr
 868 1385 3556 0.3899 0.2585
MDA-MB-231 PF562271
10
uM
LJP6
 72
hr
 868 897 3556 0.2525 0.0165
MDA-MB-231 PHA-793887
0.04
uM
LJP6
 72
hr
 868 1112 3556 0.3130 0.1296
MDA-MB-231 PHA-793887
0.12
uM
LJP6
 72
hr
 868 1159 3556 0.3264 0.1528
MDA-MB-231 PHA-793887
0.37
uM
LJP6
 72
hr
 868 985 3556 0.2777 0.0646
MDA-MB-231 PHA-793887
1.11
uM
LJP6
 72
hr
 868 914 3556 0.2576 0.0261
MDA-MB-231 PHA-793887
3.33
uM
LJP6
 72
hr
 868 852 3556 0.2401 -0.0086
MDA-MB-231 PHA-793887
10
uM
LJP6
 72
hr
 868 751 3556 0.2116 -0.0685
MDA-MB-231 QL-X-138
0.04
uM
LJP6
 72
hr
 868 2476 3556 0.6963 0.6736
MDA-MB-231 QL-X-138
0.12
uM
LJP6
 72
hr
 868 2753 3556 0.7741 0.7632
MDA-MB-231 QL-X-138
0.37
uM
LJP6
 72
hr
 868 2661 3556 0.7484 0.7341
MDA-MB-231 QL-X-138
1.11
uM
LJP6
 72
hr
 868 2483 3556 0.6990 0.6770
MDA-MB-231 QL-X-138
3.33
uM
LJP6
 72
hr
 868 1947 3556 0.5484 0.4883
MDA-MB-231 QL-X-138
10
uM
LJP6
 72
hr
 868 849 3556 0.2390 -0.0107
MDA-MB-231 QL-XII-47
0.04
uM
LJP6
 72
hr
 868 2392 3556 0.6728 0.6457
MDA-MB-231 QL-XII-47
0.12
uM
LJP6
 72
hr
 868 2063 3556 0.5807 0.5307
MDA-MB-231 QL-XII-47
0.37
uM
LJP6
 72
hr
 868 1442 3556 0.4052 0.2816
MDA-MB-231 QL-XII-47
1.11
uM
LJP6
 72
hr
 868 1018 3556 0.2863 0.0809
MDA-MB-231 QL-XII-47
3.33
uM
LJP6
 72
hr
 868 899 3556 0.2530 0.0172
MDA-MB-231 QL-XII-47
10
uM
LJP6
 72
hr
 868 810 3556 0.2279 -0.0335
MDA-MB-231 Torin1
0.04
uM
LJP6
 72
hr
 868 1971 3556 0.5545 0.4966
MDA-MB-231 Torin1
0.12
uM
LJP6
 72
hr
 868 1718 3556 0.4830 0.3981