LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 72
hr
 868 659 3556 0.1856 -0.1268
MDA-MB-231 Alvocidib
3.33
uM
LJP6
 72
hr
 868 612 3556 0.1726 -0.1584
MDA-MB-231 Alvocidib
10
uM
LJP6
 72
hr
 868 667 3556 0.1882 -0.1215
MDA-MB-231 GW843682X
0.04
uM
LJP6
 72
hr
 868 2934 3556 0.8270 0.8211
MDA-MB-231 GW843682X
0.12
uM
LJP6
 72
hr
 868 2574 3556 0.7248 0.7070
MDA-MB-231 GW843682X
0.37
uM
LJP6
 72
hr
 868 1558 3556 0.4389 0.3338
MDA-MB-231 GW843682X
1.11
uM
LJP6
 72
hr
 868 1052 3556 0.2968 0.0988
MDA-MB-231 GW843682X
3.33
uM
LJP6
 72
hr
 868 1029 3556 0.2901 0.0878
MDA-MB-231 GW843682X
10
uM
LJP6
 72
hr
 868 1218 3556 0.3430 0.1806
MDA-MB-231 HG-5-113-01
0.04
uM
LJP5
 72
hr
 868 3097 3410 0.9098 0.9064
MDA-MB-231 HG-5-113-01
0.12
uM
LJP5
 72
hr
 868 2837 3410 0.8331 0.8227
MDA-MB-231 HG-5-113-01
0.37
uM
LJP5
 72
hr
 868 2123 3410 0.6238 0.5741
MDA-MB-231 HG-5-113-01
1.11
uM
LJP5
 72
hr
 868 1673 3410 0.4912 0.3950
MDA-MB-231 HG-5-113-01
3.33
uM
LJP5
 72
hr
 868 1179 3410 0.3459 0.1675
MDA-MB-231 HG-5-113-01
10
uM
LJP5
 72
hr
 868 948 3410 0.2782 0.0456
MDA-MB-231 HG-5-88-01
0.04
uM
LJP6
 72
hr
 868 2470 3556 0.6936 0.6693
MDA-MB-231 HG-5-88-01
0.12
uM
LJP6
 72
hr
 868 2640 3556 0.7427 0.7279
MDA-MB-231 HG-5-88-01
0.37
uM
LJP6
 72
hr
 868 2445 3556 0.6874 0.6628
MDA-MB-231 HG-5-88-01
1.11
uM
LJP6
 72
hr
 868 2385 3556 0.6701 0.6418
MDA-MB-231 HG-5-88-01
3.33
uM
LJP6
 72
hr
 868 2204 3556 0.6207 0.5819
MDA-MB-231 HG-5-88-01
10
uM
LJP6
 72
hr
 868 1605 3556 0.4523 0.3530
MDA-MB-231 HG-6-64-01
0.04
uM
LJP6
 72
hr
 868 3755 3556 1.0560 1.0543
MDA-MB-231 HG-6-64-01
0.12
uM
LJP6
 72
hr
 868 3636 3556 1.0233 1.0231
MDA-MB-231 HG-6-64-01
0.37
uM
LJP6
 72
hr
 868 2755 3556 0.7752 0.7647
MDA-MB-231 HG-6-64-01
1.11
uM
LJP6
 72
hr
 868 1682 3556 0.4734 0.3846