LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 AZD8055
0.37
uM
LJP6
 72
hr
 868 1365 3556 0.3852 0.2472
MDA-MB-231 AZD8055
1.11
uM
LJP6
 72
hr
 868 1340 3556 0.3772 0.2381
MDA-MB-231 AZD8055
3.33
uM
LJP6
 72
hr
 868 1260 3556 0.3550 0.2013
MDA-MB-231 AZD8055
10
uM
LJP6
 72
hr
 868 980 3556 0.2765 0.0615
MDA-MB-231 Sorafenib
0.04
uM
LJP6
 72
hr
 868 3447 3556 0.9711 0.9714
MDA-MB-231 Sorafenib
0.12
uM
LJP6
 72
hr
 868 2798 3556 0.7880 0.7786
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 72
hr
 868 2860 3556 0.8057 0.7984
MDA-MB-231 Sorafenib
1.11
uM
LJP6
 72
hr
 868 2640 3556 0.7424 0.7275
MDA-MB-231 Sorafenib
3.33
uM
LJP6
 72
hr
 868 2760 3556 0.7769 0.7667
MDA-MB-231 Sorafenib
10
uM
LJP6
 72
hr
 868 2448 3556 0.6884 0.6645
MDA-MB-231 CP466722
0.04
uM
LJP5
 72
hr
 868 3815 3410 1.1190 1.1172
MDA-MB-231 CP466722
0.12
uM
LJP5
 72
hr
 868 3685 3410 1.0811 1.0807
MDA-MB-231 CP466722
0.37
uM
LJP5
 72
hr
 868 3509 3410 1.0290 1.0292
MDA-MB-231 CP466722
1.11
uM
LJP5
 72
hr
 868 3252 3410 0.9536 0.9517
MDA-MB-231 CP466722
3.33
uM
LJP5
 72
hr
 868 3398 3410 0.9960 0.9952
MDA-MB-231 CP466722
10
uM
LJP5
 72
hr
 868 1730 3410 0.5070 0.4168
MDA-MB-231 CP724714
0.04
uM
LJP5
 72
hr
 868 2656 3410 0.7801 0.7628
MDA-MB-231 CP724714
0.12
uM
LJP5
 72
hr
 868 2625 3410 0.7714 0.7524
MDA-MB-231 CP724714
0.37
uM
LJP5
 72
hr
 868 2643 3410 0.7754 0.7578
MDA-MB-231 CP724714
1.11
uM
LJP5
 72
hr
 868 2825 3410 0.8294 0.8192
MDA-MB-231 CP724714
3.33
uM
LJP5
 72
hr
 868 2362 3410 0.6926 0.6567
MDA-MB-231 CP724714
10
uM
LJP5
 72
hr
 868 2329 3410 0.6843 0.6492
MDA-MB-231 Alvocidib
0.04
uM
LJP6
 72
hr
 868 1237 3556 0.3481 0.1902
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 72
hr
 868 635 3556 0.1789 -0.1423
MDA-MB-231 Alvocidib
0.37
uM
LJP6
 72
hr
 868 611 3556 0.1720 -0.1586