LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 72
hr
 868 1045 3556 0.2933 0.0918
MDA-MB-231 HG-6-64-01
10
uM
LJP6
 72
hr
 868 526 3556 0.1482 -0.2197
MDA-MB-231 Neratinib
0.04
uM
LJP5
 72
hr
 868 2654 3410 0.7795 0.7618
MDA-MB-231 Neratinib
0.12
uM
LJP5
 72
hr
 868 2454 3410 0.7198 0.6929
MDA-MB-231 Neratinib
0.37
uM
LJP5
 72
hr
 868 2194 3410 0.6441 0.6003
MDA-MB-231 Neratinib
1.11
uM
LJP5
 72
hr
 868 1904 3410 0.5587 0.4877
MDA-MB-231 Neratinib
3.33
uM
LJP5
 72
hr
 868 1563 3410 0.4585 0.3445
MDA-MB-231 Neratinib
10
uM
LJP5
 72
hr
 868 715 3410 0.2099 -0.0938
MDA-MB-231 JW-7-24-1
0.04
uM
LJP6
 72
hr
 868 2560 3556 0.7192 0.6985
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 72
hr
 868 2730 3556 0.7698 0.7579
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 72
hr
 868 2426 3556 0.6821 0.6569
MDA-MB-231 JW-7-24-1
1.11
uM
LJP6
 72
hr
 868 2065 3556 0.5821 0.5322
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 72
hr
 868 1881 3556 0.5293 0.4627
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 72
hr
 868 876 3556 0.2466 0.0044
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 72
hr
 868 1648 3410 0.4845 0.3843
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 72
hr
 868 777 3556 0.2184 -0.0539
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 72
hr
 868 736 3410 0.2158 -0.0810
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 72
hr
 868 581 3556 0.1638 -0.1805
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 72
hr
 868 496 3410 0.1457 -0.2471
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 72
hr
 868 545 3556 0.1535 -0.2051
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 72
hr
 868 497 3410 0.1460 -0.2459
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 72
hr
 868 508 3556 0.1429 -0.2325
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 72
hr
 868 515 3410 0.1510 -0.2329
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 72
hr
 868 460 3556 0.1292 -0.2691
MDA-MB-231 Dasatinib
10
uM
LJP5
 72
hr
 868 633 3410 0.1857 -0.1489