LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Torin1
0.37
uM
LJP6
 72
hr
 868 1519 3556 0.4272 0.3163
MDA-MB-231 Torin1
1.11
uM
LJP6
 72
hr
 868 1323 3556 0.3725 0.2305
MDA-MB-231 Torin1
3.33
uM
LJP6
 72
hr
 868 1210 3556 0.3410 0.1778
MDA-MB-231 Torin1
10
uM
LJP6
 72
hr
 868 1017 3556 0.2864 0.0812
MDA-MB-231 Torin2
0.04
uM
LJP5
 72
hr
 868 1312 3410 0.3850 0.2329
MDA-MB-231 Torin2
0.12
uM
LJP5
 72
hr
 868 1153 3410 0.3380 0.1538
MDA-MB-231 Torin2
0.37
uM
LJP5
 72
hr
 868 1099 3410 0.3222 0.1263
MDA-MB-231 Torin2
1.11
uM
LJP5
 72
hr
 868 1038 3410 0.3043 0.0937
MDA-MB-231 Torin2
3.33
uM
LJP5
 72
hr
 868 1122 3410 0.3295 0.1390
MDA-MB-231 Torin2
10
uM
LJP5
 72
hr
 868 861 3410 0.2523 -0.0051
MDA-MB-231 WZ-4-145
0.04
uM
LJP6
 72
hr
 868 2653 3556 0.7468 0.7326
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 72
hr
 868 2935 3556 0.8263 0.8211
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 72
hr
 868 2918 3556 0.8210 0.8152
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 72
hr
 868 2672 3556 0.7523 0.7390
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 72
hr
 868 2538 3556 0.7150 0.6958
MDA-MB-231 WZ-4-145
10
uM
LJP6
 72
hr
 868 944 3556 0.2664 0.0409
MDA-MB-231 WZ3105
0.04
uM
LJP5
 72
hr
 868 682 3410 0.1996 -0.1176
MDA-MB-231 WZ3105
0.12
uM
LJP5
 72
hr
 868 716 3410 0.2101 -0.0932
MDA-MB-231 WZ3105
0.37
uM
LJP5
 72
hr
 868 735 3410 0.2153 -0.0820
MDA-MB-231 WZ3105
1.11
uM
LJP5
 72
hr
 868 722 3410 0.2118 -0.0893
MDA-MB-231 WZ3105
3.33
uM
LJP5
 72
hr
 868 682 3410 0.1996 -0.1171
MDA-MB-231 WZ3105
10
uM
LJP5
 72
hr
 868 838 3410 0.2453 -0.0197
MDA-MB-231 XMD11-50
0.04
uM
LJP6
 72
hr
 868 3077 3556 0.8636 0.8577
MDA-MB-231 XMD11-50
0.12
uM
LJP6
 72
hr
 868 2910 3556 0.8171 0.8089
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 72
hr
 868 1932 3556 0.5430 0.4809