LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 XMD11-50
1.11
uM
LJP6
 72
hr
 868 1436 3556 0.4038 0.2804
MDA-MB-231 XMD11-50
3.33
uM
LJP6
 72
hr
 868 1252 3556 0.3513 0.1944
MDA-MB-231 XMD11-50
10
uM
LJP6
 72
hr
 868 1306 3556 0.3665 0.2193
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 72
hr
 868 2646 3556 0.7451 0.7292
MDA-MB-231 XMD11-85h
0.12
uM
LJP6
 72
hr
 868 2892 3556 0.8141 0.8078
MDA-MB-231 XMD11-85h
0.37
uM
LJP6
 72
hr
 868 2817 3556 0.7929 0.7844
MDA-MB-231 XMD11-85h
1.11
uM
LJP6
 72
hr
 868 2718 3556 0.7645 0.7525
MDA-MB-231 XMD11-85h
3.33
uM
LJP6
 72
hr
 868 2457 3556 0.6910 0.6676
MDA-MB-231 XMD11-85h
10
uM
LJP6
 72
hr
 868 1495 3556 0.4204 0.3060
MDA-MB-231 XMD16-144
0.04
uM
LJP5
 72
hr
 868 1714 3410 0.5025 0.4107
MDA-MB-231 XMD16-144
0.12
uM
LJP5
 72
hr
 868 1291 3410 0.3792 0.2232
MDA-MB-231 XMD16-144
0.37
uM
LJP5
 72
hr
 868 1224 3410 0.3590 0.1898
MDA-MB-231 XMD16-144
1.11
uM
LJP5
 72
hr
 868 1310 3410 0.3843 0.2318
MDA-MB-231 XMD16-144
3.33
uM
LJP5
 72
hr
 868 1251 3410 0.3667 0.2024
MDA-MB-231 XMD16-144
10
uM
LJP5
 72
hr
 868 924 3410 0.2707 0.0307
MDA-MB-231 Erlotinib
0.04
uM
LJP5
 72
hr
 868 2901 3410 0.8495 0.8396
MDA-MB-231 Erlotinib
0.12
uM
LJP5
 72
hr
 868 3174 3410 0.9316 0.9299
MDA-MB-231 Erlotinib
0.37
uM
LJP5
 72
hr
 868 3259 3410 0.9550 0.9531
MDA-MB-231 Erlotinib
1.11
uM
LJP5
 72
hr
 868 3338 3410 0.9792 0.9786
MDA-MB-231 Erlotinib
3.33
uM
LJP5
 72
hr
 868 3356 3410 0.9837 0.9830
MDA-MB-231 Erlotinib
10
uM
LJP5
 72
hr
 868 2108 3410 0.6177 0.5659
MDA-MB-231 Gefitinib
0.04
uM
LJP6
 72
hr
 868 4066 3556 1.1438 1.1368
MDA-MB-231 Gefitinib
0.12
uM
LJP6
 72
hr
 868 3934 3556 1.1056 1.1004
MDA-MB-231 Gefitinib
0.37
uM
LJP6
 72
hr
 868 3668 3556 1.0314 1.0305
MDA-MB-231 Gefitinib
1.11
uM
LJP6
 72
hr
 868 3791 3556 1.0660 1.0636