LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Dasatinib
10
uM
LJP6
 72
hr
 868 456 3556 0.1281 -0.2730
MDA-MB-231 Tozasertib
0.04
uM
LJP5
 72
hr
 868 1053 3410 0.3092 0.1029
MDA-MB-231 Tozasertib
0.12
uM
LJP5
 72
hr
 868 1063 3410 0.3120 0.1074
MDA-MB-231 Tozasertib
0.37
uM
LJP5
 72
hr
 868 1107 3410 0.3251 0.1315
MDA-MB-231 Tozasertib
1.11
uM
LJP5
 72
hr
 868 1078 3410 0.3165 0.1158
MDA-MB-231 Tozasertib
3.33
uM
LJP5
 72
hr
 868 1128 3410 0.3314 0.1423
MDA-MB-231 Tozasertib
10
uM
LJP5
 72
hr
 868 1349 3410 0.3960 0.2505
MDA-MB-231 Imatinib
0.04
uM
LJP6
 72
hr
 868 3834 3556 1.0783 1.0756
MDA-MB-231 Imatinib
0.12
uM
LJP6
 72
hr
 868 3686 3556 1.0371 1.0364
MDA-MB-231 Imatinib
0.37
uM
LJP6
 72
hr
 868 3778 3556 1.0628 1.0609
MDA-MB-231 Imatinib
1.11
uM
LJP6
 72
hr
 868 3756 3556 1.0557 1.0533
MDA-MB-231 Imatinib
3.33
uM
LJP6
 72
hr
 868 3697 3556 1.0396 1.0385
MDA-MB-231 Imatinib
10
uM
LJP6
 72
hr
 868 3233 3556 0.9098 0.9094
MDA-MB-231 NVP-TAE684
0.04
uM
LJP6
 72
hr
 868 3248 3556 0.9146 0.9144
MDA-MB-231 NVP-TAE684
0.12
uM
LJP6
 72
hr
 868 2310 3556 0.6493 0.6168
MDA-MB-231 NVP-TAE684
0.37
uM
LJP6
 72
hr
 868 2590 3556 0.7288 0.7119
MDA-MB-231 NVP-TAE684
1.11
uM
LJP6
 72
hr
 868 1817 3556 0.5110 0.4376
MDA-MB-231 NVP-TAE684
3.33
uM
LJP6
 72
hr
 868 1419 3556 0.3990 0.2727
MDA-MB-231 NVP-TAE684
10
uM
LJP6
 72
hr
 868 698 3556 0.1964 -0.1017
MDA-MB-231 CGP60474
0.04
uM
LJP5
 72
hr
 868 2398 3410 0.7036 0.6732
MDA-MB-231 CGP60474
0.04
uM
LJP6
 72
hr
 868 870 3556 0.2448 0.0010
MDA-MB-231 CGP60474
0.12
uM
LJP5
 72
hr
 868 946 3410 0.2778 0.0447
MDA-MB-231 CGP60474
0.12
uM
LJP6
 72
hr
 868 830 3556 0.2333 -0.0225
MDA-MB-231 CGP60474
0.37
uM
LJP5
 72
hr
 868 695 3410 0.2044 -0.1065
MDA-MB-231 CGP60474
0.37
uM
LJP6
 72
hr
 868 808 3556 0.2274 -0.0348