CGP60474 - Small Molecule (ID:10025-101)
| HMS LINCS ID: |
10025-101
|
| Name: | CGP60474 |
| Alternative Names: | MLS000911536; SMR000463552 |
| LINCS ID: | LSM-1025 |
| PubChem CID: | 644215 |
| ChEBI ID: | |
| ChEMBL ID: | 300389 |
| Molecular Mass: | 355.12 |
| InChi: | InChI=1S/C18H18ClN5O/c19-14-3-1-4-15(12-14)23-18-22-9-6-16(24-18)13-5-8-21-17(11-13)20-7-2-10-25/h1,3-6,8-9,11-12,25H,2,7,10H2,(H,20,21)(H,22,23,24) |
| InChi Key: | IYNDTACKOAXKBJ-UHFFFAOYSA-N |
| SMILES: | C1=CC(=CC(=C1)Cl)NC2=NC=CC(=N2)C3=CC(=NC=C3)NCCCO |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
CDK1, CDK2, Dyrk1a | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | CDK5, CDK5R1, MTOR |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MAPT |
10 (confirmed non-binding) |
Batch Information for HMSL10025-101-1:
| HMS LINCS Batch ID: | 10025-101-1 |
| Provider: | Haoyuan chemexpress |
| Provider Batch ID: | HM-088_8-20101230 |
| Salt: | 101 |
| Molecular Formula: | C18H18ClN5O |
| Molecular Weight: | 355.82 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2011-07-15 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10025-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 03/13/2015 | PASS | HMSL10025-101-1_LCMS.pdf |
(Kd <100 nM)