LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 CGP60474
1.11
uM
LJP5
 72
hr
 868 662 3410 0.1945 -0.1284
MDA-MB-231 CGP60474
1.11
uM
LJP6
 72
hr
 868 621 3556 0.1750 -0.1523
MDA-MB-231 CGP60474
3.33
uM
LJP5
 72
hr
 868 631 3410 0.1851 -0.1497
MDA-MB-231 CGP60474
3.33
uM
LJP6
 72
hr
 868 527 3556 0.1482 -0.2187
MDA-MB-231 CGP60474
10
uM
LJP5
 72
hr
 868 586 3410 0.1720 -0.1804
MDA-MB-231 CGP60474
10
uM
LJP6
 72
hr
 868 469 3556 0.1316 -0.2652
MDA-MB-231 PD173074
0.04
uM
LJP6
 72
hr
 868 4084 3556 1.1488 1.1413
MDA-MB-231 PD173074
0.12
uM
LJP6
 72
hr
 868 3919 3556 1.1027 1.0988
MDA-MB-231 PD173074
0.37
uM
LJP6
 72
hr
 868 3593 3556 1.0112 1.0113
MDA-MB-231 PD173074
1.11
uM
LJP6
 72
hr
 868 3645 3556 1.0232 1.0205
MDA-MB-231 PD173074
3.33
uM
LJP6
 72
hr
 868 3652 3556 1.0272 1.0266
MDA-MB-231 PD173074
10
uM
LJP6
 72
hr
 868 1273 3556 0.3578 0.2062
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 72
hr
 868 2483 3410 0.7277 0.7015
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 72
hr
 868 2779 3410 0.8150 0.8031
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 72
hr
 868 2400 3410 0.7039 0.6738
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 72
hr
 868 1788 3410 0.5248 0.4426
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 72
hr
 868 1133 3410 0.3325 0.1445
MDA-MB-231 Crizotinib
10
uM
LJP5
 72
hr
 868 1086 3410 0.3188 0.1205
MDA-MB-231 BMS345541
0.04
uM
LJP6
 72
hr
 868 3554 3556 1.0011 1.0013
MDA-MB-231 BMS345541
0.12
uM
LJP6
 72
hr
 868 3667 3556 1.0338 1.0320
MDA-MB-231 BMS345541
0.37
uM
LJP6
 72
hr
 868 3262 3556 0.9188 0.9185
MDA-MB-231 BMS345541
1.11
uM
LJP6
 72
hr
 868 2372 3556 0.6673 0.6392
MDA-MB-231 BMS345541
3.33
uM
LJP6
 72
hr
 868 1189 3556 0.3351 0.1679
MDA-MB-231 BMS345541
10
uM
LJP6
 72
hr
 868 758 3556 0.2131 -0.0650
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 72
hr
 868 3394 3556 0.9563 0.9563