LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 72
hr
 868 3249 3556 0.9159 0.9151
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 72
hr
 868 3030 3556 0.8549 0.8502
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 72
hr
 868 3156 3556 0.8875 0.8853
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 72
hr
 868 3346 3556 0.9416 0.9416
MDA-MB-231 KIN001-043
10
uM
LJP6
 72
hr
 868 1857 3556 0.5217 0.4516
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 72
hr
 868 3338 3556 0.9401 0.9403
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 72
hr
 868 2848 3556 0.8034 0.7941
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 72
hr
 868 2384 3556 0.6720 0.6445
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 72
hr
 868 2114 3556 0.5956 0.5498
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 72
hr
 868 2238 3556 0.6310 0.5940
MDA-MB-231 Saracatinib
10
uM
LJP6
 72
hr
 868 1895 3556 0.5338 0.4686
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 72
hr
 868 2738 3410 0.8020 0.7868
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 72
hr
 868 2747 3410 0.8054 0.7920
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 72
hr
 868 2971 3410 0.8716 0.8656
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 72
hr
 868 2611 3410 0.7657 0.7467
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 72
hr
 868 2960 3410 0.8681 0.8618
MDA-MB-231 Sigma A6730
10
uM
LJP5
 72
hr
 868 1912 3410 0.5620 0.4930
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 72
hr
 868 2822 3410 0.8274 0.8168
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 72
hr
 868 1629 3410 0.4774 0.3742
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 72
hr
 868 1345 3410 0.3941 0.2473
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 72
hr
 868 770 3410 0.2256 -0.0608
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 72
hr
 868 811 3410 0.2380 -0.0339
MDA-MB-231 WH-4-025
10
uM
LJP5
 72
hr
 868 756 3410 0.2218 -0.0681
MDA-MB-231 R406
0.04
uM
LJP6
 72
hr
 868 3428 3556 0.9661 0.9662
MDA-MB-231 R406
0.12
uM
LJP6
 72
hr
 868 3202 3556 0.9014 0.9008