LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 R406
0.37
uM
LJP6
 72
hr
 868 3030 3556 0.8543 0.8501
MDA-MB-231 R406
1.11
uM
LJP6
 72
hr
 868 2794 3556 0.7876 0.7775
MDA-MB-231 R406
3.33
uM
LJP6
 72
hr
 868 2438 3556 0.6866 0.6624
MDA-MB-231 R406
10
uM
LJP6
 72
hr
 868 1692 3556 0.4769 0.3888
MDA-MB-231 BI-2536
0.04
uM
LJP6
 72
hr
 868 1171 3556 0.3296 0.1587
MDA-MB-231 BI-2536
0.12
uM
LJP6
 72
hr
 868 1099 3556 0.3100 0.1235
MDA-MB-231 BI-2536
0.37
uM
LJP6
 72
hr
 868 1170 3556 0.3303 0.1580
MDA-MB-231 BI-2536
1.11
uM
LJP6
 72
hr
 868 1219 3556 0.3436 0.1818
MDA-MB-231 BI-2536
3.33
uM
LJP6
 72
hr
 868 1170 3556 0.3303 0.1580
MDA-MB-231 BI-2536
10
uM
LJP6
 72
hr
 868 1222 3556 0.3438 0.1831
MDA-MB-231 A443654
0.04
uM
LJP6
 72
hr
 868 1292 3556 0.3641 0.2160
MDA-MB-231 A443654
0.12
uM
LJP6
 72
hr
 868 1018 3556 0.2860 0.0802
MDA-MB-231 A443654
0.37
uM
LJP6
 72
hr
 868 859 3556 0.2418 -0.0052
MDA-MB-231 A443654
1.11
uM
LJP6
 72
hr
 868 633 3556 0.1787 -0.1449
MDA-MB-231 A443654
3.33
uM
LJP6
 72
hr
 868 572 3556 0.1608 -0.1881
MDA-MB-231 A443654
10
uM
LJP6
 72
hr
 868 661 3556 0.1860 -0.1254
MDA-MB-231 SB590885
0.04
uM
LJP5
 72
hr
 868 3452 3410 1.0107 1.0090
MDA-MB-231 SB590885
0.12
uM
LJP5
 72
hr
 868 3269 3410 0.9577 0.9553
MDA-MB-231 SB590885
0.37
uM
LJP5
 72
hr
 868 2772 3410 0.8117 0.7978
MDA-MB-231 SB590885
1.11
uM
LJP5
 72
hr
 868 2293 3410 0.6715 0.6333
MDA-MB-231 SB590885
3.33
uM
LJP5
 72
hr
 868 1920 3410 0.5630 0.4944
MDA-MB-231 SB590885
10
uM
LJP5
 72
hr
 868 706 3410 0.2069 -0.1008
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 72
hr
 868 2501 3556 0.7036 0.6825
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 72
hr
 868 2611 3556 0.7345 0.7184
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 72
hr
 868 2611 3556 0.7346 0.7185