LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Pictilisib
1.11
uM
LJP6
 72
hr
 868 2542 3556 0.7144 0.6946
MDA-MB-231 Pictilisib
3.33
uM
LJP6
 72
hr
 868 2550 3556 0.7180 0.6992
MDA-MB-231 Pictilisib
10
uM
LJP6
 72
hr
 868 1806 3556 0.5087 0.4343
MDA-MB-231 PD184352
0.04
uM
LJP5
 72
hr
 868 3587 3410 1.0514 1.0513
MDA-MB-231 PD184352
0.12
uM
LJP5
 72
hr
 868 2957 3410 0.8667 0.8593
MDA-MB-231 PD184352
0.37
uM
LJP5
 72
hr
 868 2608 3410 0.7646 0.7450
MDA-MB-231 PD184352
1.11
uM
LJP5
 72
hr
 868 2132 3410 0.6244 0.5739
MDA-MB-231 PD184352
3.33
uM
LJP5
 72
hr
 868 1861 3410 0.5455 0.4703
MDA-MB-231 PD184352
10
uM
LJP5
 72
hr
 868 1359 3410 0.3991 0.2555
MDA-MB-231 PLX-4720
0.04
uM
LJP5
 72
hr
 868 3516 3410 1.0307 1.0301
MDA-MB-231 PLX-4720
0.12
uM
LJP5
 72
hr
 868 3613 3410 1.0591 1.0585
MDA-MB-231 PLX-4720
0.37
uM
LJP5
 72
hr
 868 3495 3410 1.0252 1.0248
MDA-MB-231 PLX-4720
1.11
uM
LJP5
 72
hr
 868 3032 3410 0.8890 0.8837
MDA-MB-231 PLX-4720
3.33
uM
LJP5
 72
hr
 868 2602 3410 0.7611 0.7380
MDA-MB-231 PLX-4720
10
uM
LJP5
 72
hr
 868 1683 3410 0.4931 0.3947
MDA-MB-231 Lapatinib
0.04
uM
LJP6
 72
hr
 868 3009 3556 0.8457 0.8414
MDA-MB-231 Lapatinib
0.12
uM
LJP6
 72
hr
 868 3327 3556 0.9362 0.9364
MDA-MB-231 Lapatinib
0.37
uM
LJP6
 72
hr
 868 3351 3556 0.9429 0.9429
MDA-MB-231 Lapatinib
1.11
uM
LJP6
 72
hr
 868 3474 3556 0.9770 0.9773
MDA-MB-231 Lapatinib
3.33
uM
LJP6
 72
hr
 868 3373 3556 0.9480 0.9475
MDA-MB-231 Lapatinib
10
uM
LJP6
 72
hr
 868 2607 3556 0.7340 0.7180
MDA-MB-231 Sirolimus
0.04
uM
LJP6
 72
hr
 868 2868 3556 0.8076 0.8006
MDA-MB-231 Sirolimus
0.12
uM
LJP6
 72
hr
 868 2728 3556 0.7672 0.7556
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 72
hr
 868 2974 3556 0.8356 0.8300
MDA-MB-231 Sirolimus
1.11
uM
LJP6
 72
hr
 868 2714 3556 0.7631 0.7508