LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 SU11274
0.12
uM
LJP5
 72
hr
 868 3561 3410 1.0434 1.0425
MDA-MB-231 SU11274
0.37
uM
LJP5
 72
hr
 868 3611 3410 1.0585 1.0583
MDA-MB-231 SU11274
1.11
uM
LJP5
 72
hr
 868 3394 3410 0.9946 0.9940
MDA-MB-231 SU11274
3.33
uM
LJP5
 72
hr
 868 3127 3410 0.9165 0.9132
MDA-MB-231 SU11274
10
uM
LJP5
 72
hr
 868 1257 3410 0.3686 0.2059
MDA-MB-231 Canertinib
0.04
uM
LJP6
 72
hr
 868 3831 3556 1.0766 1.0730
MDA-MB-231 Canertinib
0.12
uM
LJP6
 72
hr
 868 3383 3556 0.9504 0.9493
MDA-MB-231 Canertinib
0.37
uM
LJP6
 72
hr
 868 3162 3556 0.8885 0.8863
MDA-MB-231 Canertinib
1.11
uM
LJP6
 72
hr
 868 2820 3556 0.7914 0.7800
MDA-MB-231 Canertinib
3.33
uM
LJP6
 72
hr
 868 2305 3556 0.6467 0.6117
MDA-MB-231 Canertinib
10
uM
LJP6
 72
hr
 868 617 3556 0.1728 -0.1616
MDA-MB-231 NVP-AEW541
0.04
uM
LJP5
 72
hr
 868 3531 3410 1.0372 1.0376
MDA-MB-231 NVP-AEW541
0.12
uM
LJP5
 72
hr
 868 3503 3410 1.0286 1.0289
MDA-MB-231 NVP-AEW541
0.37
uM
LJP5
 72
hr
 868 3583 3410 1.0521 1.0514
MDA-MB-231 NVP-AEW541
1.11
uM
LJP5
 72
hr
 868 3410 3410 1.0013 1.0015
MDA-MB-231 NVP-AEW541
3.33
uM
LJP5
 72
hr
 868 3380 3410 0.9920 0.9922
MDA-MB-231 NVP-AEW541
10
uM
LJP5
 72
hr
 868 1340 3410 0.3941 0.2460
MDA-MB-231 PHA-665752
0.04
uM
LJP5
 72
hr
 868 3586 3410 1.0523 1.0523
MDA-MB-231 PHA-665752
0.12
uM
LJP5
 72
hr
 868 3754 3410 1.1029 1.1016
MDA-MB-231 PHA-665752
0.37
uM
LJP5
 72
hr
 868 3640 3410 1.0679 1.0679
MDA-MB-231 PHA-665752
1.11
uM
LJP5
 72
hr
 868 3577 3410 1.0503 1.0495
MDA-MB-231 PHA-665752
3.33
uM
LJP5
 72
hr
 868 3294 3410 0.9668 0.9659
MDA-MB-231 PHA-665752
10
uM
LJP5
 72
hr
 868 653 3410 0.1922 -0.1350
MDA-MB-231 PI103
0.04
uM
LJP6
 72
hr
 868 2869 3556 0.8062 0.7982
MDA-MB-231 PI103
0.12
uM
LJP6
 72
hr
 868 2455 3556 0.6911 0.6673