LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 PI103
0.37
uM
LJP6
 72
hr
 868 2226 3556 0.6264 0.5891
MDA-MB-231 PI103
1.11
uM
LJP6
 72
hr
 868 1950 3556 0.5482 0.4878
MDA-MB-231 PI103
3.33
uM
LJP6
 72
hr
 868 1987 3556 0.5592 0.5024
MDA-MB-231 PI103
10
uM
LJP6
 72
hr
 868 1482 3556 0.4174 0.3008
MDA-MB-231 Dovitinib
0.04
uM
LJP5
 72
hr
 868 2712 3410 0.7947 0.7792
MDA-MB-231 Dovitinib
0.12
uM
LJP5
 72
hr
 868 2408 3410 0.7065 0.6772
MDA-MB-231 Dovitinib
0.37
uM
LJP5
 72
hr
 868 1891 3410 0.5541 0.4822
MDA-MB-231 Dovitinib
1.11
uM
LJP5
 72
hr
 868 1755 3410 0.5151 0.4290
MDA-MB-231 Dovitinib
3.33
uM
LJP5
 72
hr
 868 1649 3410 0.4844 0.3848
MDA-MB-231 Dovitinib
10
uM
LJP5
 72
hr
 868 1494 3410 0.4390 0.3174
MDA-MB-231 GSK 690693
0.04
uM
LJP5
 72
hr
 868 2658 3410 0.7794 0.7627
MDA-MB-231 GSK 690693
0.12
uM
LJP5
 72
hr
 868 3040 3410 0.8911 0.8861
MDA-MB-231 GSK 690693
0.37
uM
LJP5
 72
hr
 868 3036 3410 0.8899 0.8847
MDA-MB-231 GSK 690693
1.11
uM
LJP5
 72
hr
 868 3209 3410 0.9404 0.9375
MDA-MB-231 GSK 690693
3.33
uM
LJP5
 72
hr
 868 3459 3410 1.0139 1.0134
MDA-MB-231 GSK 690693
10
uM
LJP5
 72
hr
 868 3140 3410 0.9213 0.9189
MDA-MB-231 SNS-032
0.04
uM
LJP6
 72
hr
 868 1240 3556 0.3487 0.1910
MDA-MB-231 SNS-032
0.12
uM
LJP6
 72
hr
 868 821 3556 0.2309 -0.0273
MDA-MB-231 SNS-032
0.37
uM
LJP6
 72
hr
 868 771 3556 0.2172 -0.0562
MDA-MB-231 SNS-032
1.11
uM
LJP6
 72
hr
 868 748 3556 0.2105 -0.0706
MDA-MB-231 SNS-032
3.33
uM
LJP6
 72
hr
 868 847 3556 0.2382 -0.0128
MDA-MB-231 SNS-032
10
uM
LJP6
 72
hr
 868 782 3556 0.2196 -0.0517
MDA-MB-231 Afatinib
0.04
uM
LJP6
 72
hr
 868 2549 3556 0.7165 0.6971
MDA-MB-231 Afatinib
0.12
uM
LJP6
 72
hr
 868 2948 3556 0.8290 0.8237
MDA-MB-231 Afatinib
0.37
uM
LJP6
 72
hr
 868 2774 3556 0.7803 0.7690