LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Afatinib
1.11
uM
LJP6
 72
hr
 868 2626 3556 0.7383 0.7222
MDA-MB-231 Afatinib
3.33
uM
LJP6
 72
hr
 868 2182 3556 0.6146 0.5740
MDA-MB-231 Afatinib
10
uM
LJP6
 72
hr
 868 732 3556 0.2054 -0.0831
MDA-MB-231 GSK1904529A
0.04
uM
LJP6
 72
hr
 868 2588 3556 0.7271 0.7089
MDA-MB-231 GSK1904529A
0.12
uM
LJP6
 72
hr
 868 2916 3556 0.8193 0.8122
MDA-MB-231 GSK1904529A
0.37
uM
LJP6
 72
hr
 868 3091 3556 0.8700 0.8678
MDA-MB-231 GSK1904529A
1.11
uM
LJP6
 72
hr
 868 3232 3556 0.9098 0.9094
MDA-MB-231 GSK1904529A
3.33
uM
LJP6
 72
hr
 868 3396 3556 0.9543 0.9531
MDA-MB-231 GSK1904529A
10
uM
LJP6
 72
hr
 868 3375 3556 0.9501 0.9506
MDA-MB-231 Linsitinib
0.04
uM
LJP5
 72
hr
 868 2600 3410 0.7628 0.7437
MDA-MB-231 Linsitinib
0.12
uM
LJP5
 72
hr
 868 2755 3410 0.8072 0.7936
MDA-MB-231 Linsitinib
0.37
uM
LJP5
 72
hr
 868 2875 3410 0.8423 0.8325
MDA-MB-231 Linsitinib
1.11
uM
LJP5
 72
hr
 868 2978 3410 0.8715 0.8626
MDA-MB-231 Linsitinib
3.33
uM
LJP5
 72
hr
 868 2739 3410 0.8025 0.7883
MDA-MB-231 Linsitinib
10
uM
LJP5
 72
hr
 868 2212 3410 0.6486 0.6059
MDA-MB-231 Ruxolitinib
0.04
uM
LJP5
 72
hr
 868 3160 3410 0.9262 0.9232
MDA-MB-231 Ruxolitinib
0.12
uM
LJP5
 72
hr
 868 3094 3410 0.9054 0.8985
MDA-MB-231 Ruxolitinib
0.37
uM
LJP5
 72
hr
 868 3106 3410 0.9104 0.9060
MDA-MB-231 Ruxolitinib
1.11
uM
LJP5
 72
hr
 868 3326 3410 0.9741 0.9723
MDA-MB-231 Ruxolitinib
3.33
uM
LJP5
 72
hr
 868 3306 3410 0.9690 0.9679
MDA-MB-231 Ruxolitinib
10
uM
LJP5
 72
hr
 868 2760 3410 0.8086 0.7948
MDA-MB-231 Momelotinib
0.04
uM
LJP5
 72
hr
 868 2772 3410 0.8114 0.7968
MDA-MB-231 Momelotinib
0.12
uM
LJP5
 72
hr
 868 2674 3410 0.7824 0.7628
MDA-MB-231 Momelotinib
0.37
uM
LJP5
 72
hr
 868 2590 3410 0.7592 0.7392
MDA-MB-231 Momelotinib
1.11
uM
LJP5
 72
hr
 868 2273 3410 0.6660 0.6272