LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 MK2206
10
uM
LJP6
72
hr
868 1139 3556 0.3207 0.1419
MDA-MB-231 AZD-6482
0.04
uM
LJP5
72
hr
868 3178 3410 0.9307 0.9270
MDA-MB-231 AZD-6482
0.12
uM
LJP5
72
hr
868 3065 3410 0.8992 0.8955
MDA-MB-231 AZD-6482
0.37
uM
LJP5
72
hr
868 3027 3410 0.8877 0.8827
MDA-MB-231 AZD-6482
1.11
uM
LJP5
72
hr
868 2355 3410 0.6906 0.6573
MDA-MB-231 AZD-6482
3.33
uM
LJP5
72
hr
868 1993 3410 0.5836 0.5195
MDA-MB-231 AZD-6482
10
uM
LJP5
72
hr
868 1260 3410 0.3692 0.2053
MDA-MB-231 NU7441
0.04
uM
LJP5
72
hr
868 3623 3410 1.0613 1.0599
MDA-MB-231 NU7441
0.12
uM
LJP5
72
hr
868 3276 3410 0.9621 0.9604
MDA-MB-231 NU7441
0.37
uM
LJP5
72
hr
868 2800 3410 0.8220 0.8098
MDA-MB-231 NU7441
1.11
uM
LJP5
72
hr
868 2642 3410 0.7756 0.7585
MDA-MB-231 NU7441
3.33
uM
LJP5
72
hr
868 1978 3410 0.5812 0.5183
MDA-MB-231 NU7441
10
uM
LJP5
72
hr
868 1159 3410 0.3402 0.1580
MDA-MB-231 OSI-027
0.04
uM
LJP6
72
hr
868 3680 3556 1.0362 1.0355
MDA-MB-231 OSI-027
0.12
uM
LJP6
72
hr
868 3222 3556 0.9072 0.9065
MDA-MB-231 OSI-027
0.37
uM
LJP6
72
hr
868 2835 3556 0.7991 0.7899
MDA-MB-231 OSI-027
1.11
uM
LJP6
72
hr
868 2527 3556 0.7115 0.6919
MDA-MB-231 OSI-027
3.33
uM
LJP6
72
hr
868 2262 3556 0.6365 0.6013
MDA-MB-231 OSI-027
10
uM
LJP6
72
hr
868 1656 3556 0.4656 0.3730
MDA-MB-231 WYE-125132
0.04
uM
LJP6
72
hr
868 2273 3556 0.6400 0.6059
MDA-MB-231 WYE-125132
0.12
uM
LJP6
72
hr
868 2075 3556 0.5828 0.5326
MDA-MB-231 WYE-125132
0.37
uM
LJP6
72
hr
868 1873 3556 0.5265 0.4586
MDA-MB-231 WYE-125132
1.11
uM
LJP6
72
hr
868 1776 3556 0.4994 0.4209
MDA-MB-231 WYE-125132
3.33
uM
LJP6
72
hr
868 1617 3556 0.4545 0.3568
MDA-MB-231 WYE-125132
10
uM
LJP6
72
hr
868 1386 3556 0.3895 0.2575