LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 11 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 1. - Dataset (ID:20248)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MDA-MB-231 | MK2206 | 10 | uM | LJP6 | 72 | hr | 868 | 1139 | 3556 | 0.3207 | 0.1419 |
MDA-MB-231 | AZD-6482 | 0.04 | uM | LJP5 | 72 | hr | 868 | 3178 | 3410 | 0.9307 | 0.9270 |
MDA-MB-231 | AZD-6482 | 0.12 | uM | LJP5 | 72 | hr | 868 | 3065 | 3410 | 0.8992 | 0.8955 |
MDA-MB-231 | AZD-6482 | 0.37 | uM | LJP5 | 72 | hr | 868 | 3027 | 3410 | 0.8877 | 0.8827 |
MDA-MB-231 | AZD-6482 | 1.11 | uM | LJP5 | 72 | hr | 868 | 2355 | 3410 | 0.6906 | 0.6573 |
MDA-MB-231 | AZD-6482 | 3.33 | uM | LJP5 | 72 | hr | 868 | 1993 | 3410 | 0.5836 | 0.5195 |
MDA-MB-231 | AZD-6482 | 10 | uM | LJP5 | 72 | hr | 868 | 1260 | 3410 | 0.3692 | 0.2053 |
MDA-MB-231 | NU7441 | 0.04 | uM | LJP5 | 72 | hr | 868 | 3623 | 3410 | 1.0613 | 1.0599 |
MDA-MB-231 | NU7441 | 0.12 | uM | LJP5 | 72 | hr | 868 | 3276 | 3410 | 0.9621 | 0.9604 |
MDA-MB-231 | NU7441 | 0.37 | uM | LJP5 | 72 | hr | 868 | 2800 | 3410 | 0.8220 | 0.8098 |
MDA-MB-231 | NU7441 | 1.11 | uM | LJP5 | 72 | hr | 868 | 2642 | 3410 | 0.7756 | 0.7585 |
MDA-MB-231 | NU7441 | 3.33 | uM | LJP5 | 72 | hr | 868 | 1978 | 3410 | 0.5812 | 0.5183 |
MDA-MB-231 | NU7441 | 10 | uM | LJP5 | 72 | hr | 868 | 1159 | 3410 | 0.3402 | 0.1580 |
MDA-MB-231 | OSI-027 | 0.04 | uM | LJP6 | 72 | hr | 868 | 3680 | 3556 | 1.0362 | 1.0355 |
MDA-MB-231 | OSI-027 | 0.12 | uM | LJP6 | 72 | hr | 868 | 3222 | 3556 | 0.9072 | 0.9065 |
MDA-MB-231 | OSI-027 | 0.37 | uM | LJP6 | 72 | hr | 868 | 2835 | 3556 | 0.7991 | 0.7899 |
MDA-MB-231 | OSI-027 | 1.11 | uM | LJP6 | 72 | hr | 868 | 2527 | 3556 | 0.7115 | 0.6919 |
MDA-MB-231 | OSI-027 | 3.33 | uM | LJP6 | 72 | hr | 868 | 2262 | 3556 | 0.6365 | 0.6013 |
MDA-MB-231 | OSI-027 | 10 | uM | LJP6 | 72 | hr | 868 | 1656 | 3556 | 0.4656 | 0.3730 |
MDA-MB-231 | WYE-125132 | 0.04 | uM | LJP6 | 72 | hr | 868 | 2273 | 3556 | 0.6400 | 0.6059 |
MDA-MB-231 | WYE-125132 | 0.12 | uM | LJP6 | 72 | hr | 868 | 2075 | 3556 | 0.5828 | 0.5326 |
MDA-MB-231 | WYE-125132 | 0.37 | uM | LJP6 | 72 | hr | 868 | 1873 | 3556 | 0.5265 | 0.4586 |
MDA-MB-231 | WYE-125132 | 1.11 | uM | LJP6 | 72 | hr | 868 | 1776 | 3556 | 0.4994 | 0.4209 |
MDA-MB-231 | WYE-125132 | 3.33 | uM | LJP6 | 72 | hr | 868 | 1617 | 3556 | 0.4545 | 0.3568 |
MDA-MB-231 | WYE-125132 | 10 | uM | LJP6 | 72 | hr | 868 | 1386 | 3556 | 0.3895 | 0.2575 |